Year |
Citation |
Score |
2024 |
Raghuwanshi S, Zhang X, Arbieva Z, Khan I, Mohammed H, Wang Z, Domling A, Camacho CJ, Gartel AL. Novel FOXM1 inhibitor STL001 sensitizes human cancers to a broad-spectrum of cancer therapies. Cell Death Discovery. 10: 211. PMID 38697979 DOI: 10.1038/s41420-024-01929-0 |
0.443 |
|
2023 |
Raghuwanshi S, Gartel AL. Small-molecule inhibitors targeting FOXM1: Current challenges and future perspectives in cancer treatments. Biochimica Et Biophysica Acta. Reviews On Cancer. 1878: 189015. PMID 37913940 DOI: 10.1016/j.bbcan.2023.189015 |
0.428 |
|
2021 |
Chesnokov MS, Borhani S, Halasi M, Arbieva Z, Khan I, Gartel AL. FOXM1-AKT Positive Regulation Loop Provides Venetoclax Resistance in AML. Frontiers in Oncology. 11: 696532. PMID 34381718 DOI: 10.3389/fonc.2021.696532 |
0.753 |
|
2021 |
Chesnokov MS, Halasi M, Borhani S, Arbieva Z, Shah BN, Oerlemans R, Khan I, Camacho CJ, Gartel AL. Novel FOXM1 inhibitor identified via gene network analysis induces autophagic FOXM1 degradation to overcome chemoresistance of human cancer cells. Cell Death & Disease. 12: 704. PMID 34262016 DOI: 10.1038/s41419-021-03978-0 |
0.774 |
|
2020 |
Borhani S, Gartel AL. FOXM1: a potential therapeutic target in human solid cancers. Expert Opinion On Therapeutic Targets. 1-13. PMID 32067537 DOI: 10.1080/14728222.2020.1727888 |
0.425 |
|
2018 |
Khan I, Halasi M, Patel A, Schultz R, Kalakota N, Chen YH, Aardsma N, Liu L, Crispino JD, Mahmud N, Frankfurt O, Gartel AL. FOXM1 contributes to treatment failure in acute myeloid leukemia. Jci Insight. 3. PMID 30089730 DOI: 10.1172/Jci.Insight.121583 |
0.727 |
|
2018 |
Halasi M, Hitchinson B, Shah BN, Váraljai R, Khan I, Benevolenskaya EV, Gaponenko V, Arbiser JL, Gartel AL. Honokiol is a FOXM1 antagonist. Cell Death & Disease. 9: 84. PMID 29367668 DOI: 10.1038/S41419-017-0156-7 |
0.755 |
|
2017 |
Gartel AL. FOXM1 in Cancer: Interactions and Vulnerabilities. Cancer Research. PMID 28584182 DOI: 10.1158/0008-5472.CAN-16-3566 |
0.419 |
|
2016 |
Khan I, Halasi M, Zia MF, Gann P, Gaitonde S, Mahmud N, Gartel AL. Nuclear FOXM1 drives chemoresistance in AML. Leukemia. PMID 27694928 DOI: 10.1038/Leu.2016.270 |
0.652 |
|
2016 |
Halasi M, Váraljai R, Benevolenskaya E, Gartel AL. A Novel Function of Molecular Chaperone HSP70: SUPPRESSION OF ONCOGENIC FOXM1 AFTER PROTEOTOXIC STRESS. The Journal of Biological Chemistry. 291: 142-8. PMID 26559972 DOI: 10.1074/Jbc.M115.678227 |
0.75 |
|
2016 |
Khan I, Gartel A, Halasi M. Inhibition of FOXM1 By Ixazomib Confers Chemosensitivity in NPM1-Wild Type Acute Myeloid Leukemia Blood. 128: 1577-1577. DOI: 10.1182/Blood.V128.22.1577.1577 |
0.773 |
|
2015 |
Pandit B, Gartel AL. Mutual Regulation of FOXM1, NPM and ARF Proteins. Journal of Cancer. 6: 538-41. PMID 26000045 DOI: 10.7150/Jca.11766 |
0.379 |
|
2015 |
Gartel AL. Targeting FOXM1 auto-regulation in cancer. Cancer Biology & Therapy. 16: 185-6. PMID 25603426 DOI: 10.4161/15384047.2014.987566 |
0.349 |
|
2015 |
Khan I, Zia M, Halasi M, Gann P, Gaitonde S, Gartel A. FOXM1 Binds Nucleophosmin in AML and Confers Resistance to Chemotherapy Blood. 126: 2467-2467. DOI: 10.1182/Blood.V126.23.2467.2467 |
0.753 |
|
2014 |
Halasi M, Pandit B, Gartel AL. Proteasome inhibitors suppress the protein expression of mutant p53. Cell Cycle (Georgetown, Tex.). 13: 3202-6. PMID 25485499 DOI: 10.4161/15384101.2014.950132 |
0.728 |
|
2014 |
Gartel AL. Suppression of the Oncogenic Transcription Factor FOXM1 by Proteasome Inhibitors. Scientifica. 2014: 596528. PMID 25093142 DOI: 10.1155/2014/596528 |
0.52 |
|
2014 |
Halasi M, Gartel AL. Sa1376 FOXM1 As a Potential Target in Pancreatic Cancer Gastroenterology. 146: S-277. DOI: 10.1016/S0016-5085(14)60978-1 |
0.713 |
|
2013 |
Halasi M, Wang M, Chavan TS, Gaponenko V, Hay N, Gartel AL. ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors. The Biochemical Journal. 454: 201-8. PMID 23772801 DOI: 10.1042/Bj20130282 |
0.721 |
|
2013 |
Halasi M, Pandit B, Wang M, Nogueira V, Hay N, Gartel AL. Combination of oxidative stress and FOXM1 inhibitors induces apoptosis in cancer cells and inhibits xenograft tumor growth. The American Journal of Pathology. 183: 257-65. PMID 23665201 DOI: 10.1016/J.Ajpath.2013.03.012 |
0.777 |
|
2013 |
Halasi M, Gartel AL. FOX(M1) news--it is cancer. Molecular Cancer Therapeutics. 12: 245-54. PMID 23443798 DOI: 10.1158/1535-7163.Mct-12-0712 |
0.771 |
|
2013 |
Halasi M, Gartel AL. Targeting FOXM1 in cancer. Biochemical Pharmacology. 85: 644-52. PMID 23103567 DOI: 10.1016/J.Bcp.2012.10.013 |
0.767 |
|
2012 |
Gartel AL. Paradoxical inhibition of cellular protein expression by proteasome inhibitors. Biomolecular Concepts. 3: 593-5. PMID 25436560 DOI: 10.1515/bmc-2012-0029 |
0.36 |
|
2012 |
Wang M, Halasi M, Kabirov K, Banerjee A, Landolfi J, Lyubimov AV, Gartel AL. Combination treatment with bortezomib and thiostrepton is effective against tumor formation in mouse models of DEN/PB-induced liver carcinogenesis. Cell Cycle (Georgetown, Tex.). 11: 3370-2. PMID 22894930 DOI: 10.4161/Cc.21290 |
0.731 |
|
2012 |
Halasi M, Gartel AL. Suppression of FOXM1 sensitizes human cancer cells to cell death induced by DNA-damage. Plos One. 7: e31761. PMID 22393369 DOI: 10.1371/Journal.Pone.0031761 |
0.75 |
|
2012 |
Wang M, Gartel AL. Combination with bortezomib enhances the antitumor effects of nanoparticle-encapsulated thiostrepton. Cancer Biology & Therapy. 13: 184-9. PMID 22353937 DOI: 10.4161/cbt.13.3.18875 |
0.395 |
|
2012 |
Gartel AL. Mechanisms of apoptosis induced by anticancer compounds in melanoma cells. Current Topics in Medicinal Chemistry. 12: 50-2. PMID 22280162 DOI: 10.2174/156802612798919196 |
0.406 |
|
2012 |
Wang M, Gartel A. Abstract LB-356: Micelle-encapsulated thiostrepton: an effective nanomedicine for inhibiting tumor growth Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-356 |
0.49 |
|
2012 |
Gartel AL. Skin cancer: Apoptosis mechanisms induced by antineoplastic compounds in melanoma cells Haut. 23: 152. |
0.341 |
|
2011 |
Wang M, Gartel AL. The suppression of FOXM1 and its targets in breast cancer xenograft tumors by siRNA. Oncotarget. 2: 1218-26. PMID 22203467 DOI: 10.18632/oncotarget.359 |
0.394 |
|
2011 |
Bhat UG, Jagadeeswaran R, Halasi M, Gartel AL. Nucleophosmin interacts with FOXM1 and modulates the level and localization of FOXM1 in human cancer cells. The Journal of Biological Chemistry. 286: 41425-33. PMID 21979956 DOI: 10.1074/Jbc.M111.270843 |
0.761 |
|
2011 |
Pandit B, Gartel AL. FoxM1 knockdown sensitizes human cancer cells to proteasome inhibitor-induced apoptosis but not to autophagy. Cell Cycle (Georgetown, Tex.). 10: 3269-73. PMID 21941087 DOI: 10.4161/Cc.10.19.17735 |
0.45 |
|
2011 |
Wang M, Gartel AL. Micelle-encapsulated thiostrepton as an effective nanomedicine for inhibiting tumor growth and for suppressing FOXM1 in human xenografts. Molecular Cancer Therapeutics. 10: 2287-97. PMID 21903609 DOI: 10.1158/1535-7163.MCT-11-0536 |
0.391 |
|
2011 |
Pandit B, Gartel AL. Thiazole antibiotic thiostrepton synergize with bortezomib to induce apoptosis in cancer cells. Plos One. 6: e17110. PMID 21365012 DOI: 10.1371/Journal.Pone.0017110 |
0.455 |
|
2011 |
Pandit B, Gartel AL. Proteasome inhibitors induce p53-independent apoptosis in human cancer cells. The American Journal of Pathology. 178: 355-60. PMID 21224072 DOI: 10.1016/J.Ajpath.2010.11.010 |
0.484 |
|
2010 |
Bhat UG, Pandit B, Gartel AL. ARC synergizes with ABT-737 to induce apoptosis in human cancer cells. Molecular Cancer Therapeutics. 9: 1688-96. PMID 20515947 DOI: 10.1158/1535-7163.Mct-09-0919 |
0.474 |
|
2010 |
Halasi M, Zhao H, Dahari H, Bhat UG, Gonzalez EB, Lyubimo AV, Tonetti DA, Gartel AL. Thiazole antibiotics against breast cancer. Cell Cycle (Georgetown, Tex.). 9: 1214-7. PMID 20410687 DOI: 10.4161/Cc.9.6.10955 |
0.758 |
|
2010 |
Bhat UG, Gartel AL. Nucleoside analog ARC targets Mcl-1 to induce apoptosis in leukemia cells Leukemia. 24: 851-855. PMID 20164850 DOI: 10.1038/leu.2010.3 |
0.342 |
|
2010 |
Gartel AL. A new target for proteasome inhibitors: FoxM1. Expert Opinion On Investigational Drugs. 19: 235-42. PMID 20074015 DOI: 10.1517/13543780903563364 |
0.479 |
|
2010 |
Pandit B, Gartel AL. New potential anti-cancer agents synergize with bortezomib and ABT-737 against prostate cancer. The Prostate. 70: 825-33. PMID 20058240 DOI: 10.1002/Pros.21116 |
0.417 |
|
2009 |
Pandit B, Halasi M, Gartel AL. p53 negatively regulates expression of FoxM1. Cell Cycle (Georgetown, Tex.). 8: 3425-7. PMID 19806025 DOI: 10.4161/Cc.8.20.9628 |
0.747 |
|
2009 |
Bhat UG, Halasi M, Gartel AL. FoxM1 is a general target for proteasome inhibitors. Plos One. 4: e6593. PMID 19672316 DOI: 10.1371/Journal.Pone.0006593 |
0.782 |
|
2009 |
Halasi M, Schraufnagel DP, Gartel AL. Wild-type p53 protects normal cells against apoptosis induced by thiostrepton. Cell Cycle (Georgetown, Tex.). 8: 2850-1. PMID 19652535 DOI: 10.4161/Cc.8.17.9414 |
0.758 |
|
2009 |
Gartel AL. p21(WAF1/CIP1) and cancer: a shifting paradigm? Biofactors (Oxford, England). 35: 161-4. PMID 19449443 DOI: 10.1002/biof.26 |
0.428 |
|
2009 |
Bhat UG, Halasi M, Gartel AL. Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells. Plos One. 4: e5592. PMID 19440351 DOI: 10.1371/Journal.Pone.0005592 |
0.794 |
|
2009 |
Halasi M, Gartel AL. A novel mode of FoxM1 regulation: positive auto-regulatory loop. Cell Cycle (Georgetown, Tex.). 8: 1966-7. PMID 19411834 DOI: 10.4161/Cc.8.12.8708 |
0.736 |
|
2008 |
Gartel AL. [Novel anticancer compounds induce apoptosis in human tumor cells]. Ai Zheng = Aizheng = Chinese Journal of Cancer. 27: 675-6. PMID 18606057 |
0.321 |
|
2008 |
Bhat UG, Zipfel PA, Tyler DS, Gartel AL. Novel anticancer compounds induce apoptosis in melanoma cells. Cell Cycle (Georgetown, Tex.). 7: 1851-5. PMID 18583930 |
0.413 |
|
2008 |
Gartel AL. Transcriptional inhibitors, p53 and apoptoss. Biochimica Et Biophysica Acta. 1786: 83-6. PMID 18503775 DOI: 10.1016/j.bbcan.2008.04.004 |
0.396 |
|
2008 |
Gartel AL. FoxM1 inhibitors as potential anticancer drugs. Expert Opinion On Therapeutic Targets. 12: 663-5. PMID 18479213 DOI: 10.1517/14728222.12.6.663 |
0.345 |
|
2008 |
Radhakrishnan SK, Gartel AL. FOXM1: the Achilles' heel of cancer? Nature Reviews. Cancer. 8: c1; author reply c2. PMID 18297053 DOI: 10.1038/nrc2223-c1 |
0.303 |
|
2008 |
Bhat UG, Gartel AL. Differential sensitivity of human colon cancer cell lines to the nucleoside analogs ARC and DRB. International Journal of Cancer. 122: 1426-9. PMID 17999411 DOI: 10.1002/ijc.23239 |
0.437 |
|
2008 |
Radhakrishnan SK, Halasi M, Bhat UG, Kurmasheva RT, Houghton PJ, Gartel AL. Proapoptotic compound ARC targets Akt and N-myc in neuroblastoma cells. Oncogene. 27: 694-9. PMID 17724478 DOI: 10.1038/Sj.Onc.1210692 |
0.749 |
|
2008 |
Radhakrishnan SK, Bhat UG, Halasi M, Gartel AL. P-TEFb inhibitors interfere with activation of p53 by DNA-damaging agents. Oncogene. 27: 1306-9. PMID 17724473 DOI: 10.1038/Sj.Onc.1210737 |
0.722 |
|
2007 |
Gartel AL. P21(WAF1/CIP1) may be a tumor suppressor after all. Cancer Biology & Therapy. 6: 1171-2. PMID 17726367 |
0.376 |
|
2006 |
Radhakrishnan SK, Bhat UG, Hughes DE, Wang IC, Costa RH, Gartel AL. Identification of a chemical inhibitor of the oncogenic transcription factor forkhead box M1. Cancer Research. 66: 9731-5. PMID 17018632 DOI: 10.1158/0008-5472.CAN-06-1576 |
0.449 |
|
2006 |
Radhakrishnan SK, Gartel AL. A novel transcriptional inhibitor induces apoptosis in tumor cells and exhibits antiangiogenic activity. Cancer Research. 66: 3264-70. PMID 16540679 DOI: 10.1158/0008-5472.CAN-05-3940 |
0.433 |
|
2006 |
Radhakrishnan SK, Gierut J, Gartel AL. Multiple alternate p21 transcripts are regulated by p53 in human cells Oncogene. 25: 1812-1815. PMID 16261158 DOI: 10.1038/Sj.Onc.1209195 |
0.303 |
|
2005 |
Gartel AL, Radhakrishnan SK. Lost in transcription: p21 repression, mechanisms, and consequences. Cancer Research. 65: 3980-5. PMID 15899785 DOI: 10.1158/0008-5472.CAN-04-3995 |
0.393 |
|
2005 |
Radhakrishnan SK, Gartel AL. The PPAR-gamma agonist pioglitazone post-transcriptionally induces p21 in PC3 prostate cancer but not in other cell lines. Cell Cycle (Georgetown, Tex.). 4: 582-4. PMID 15738655 |
0.378 |
|
2004 |
Datta A, Nag A, Pan W, Hay N, Gartel AL, Colamonici O, Mori Y, Raychaudhuri P. Myc-ARF (alternate reading frame) interaction inhibits the functions of Myc. The Journal of Biological Chemistry. 279: 36698-707. PMID 15199070 DOI: 10.1074/Jbc.M312305200 |
0.322 |
|
2004 |
Radhakrishnan SK, Feliciano CS, Najmabadi F, Haegebarth A, Kandel ES, Tyner AL, Gartel AL. Constitutive expression of E2F-1 leads to p21-dependent cell cycle arrest in S phase of the cell cycle. Oncogene. 23: 4173-6. PMID 15048076 DOI: 10.1038/sj.onc.1207571 |
0.342 |
|
2003 |
Gartel AL, Feliciano C, Tyner AL. A new method for determining the status of p53 in tumor cell lines of different origin. Oncology Research. 13: 405-8. PMID 12725531 |
0.404 |
|
2002 |
Gartel AL, Tyner AL. The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Molecular Cancer Therapeutics. 1: 639-49. PMID 12479224 |
0.412 |
|
2002 |
Kandel ES, Skeen J, Majewski N, Di Cristofano A, Pandolfi PP, Feliciano CS, Gartel A, Hay N. Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage. Molecular and Cellular Biology. 22: 7831-41. PMID 12391152 DOI: 10.1128/Mcb.22.22.7831-7841.2002 |
0.324 |
|
2001 |
Gartel AL, Ye X, Goufman E, Shianov P, Hay N, Najmabadi F, Tyner AL. Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3. Proceedings of the National Academy of Sciences of the United States of America. 98: 4510-5. PMID 11274368 DOI: 10.1073/Pnas.081074898 |
0.304 |
|
1998 |
Gartel AL, Goufman E, Tevosian SG, Shih H, Yee AS, Tyner AL. Activation and repression of p21(WAF1/CIP1) transcription by RB binding proteins. Oncogene. 17: 3463-9. PMID 10030670 DOI: 10.1038/sj.onc.1202240 |
0.307 |
|
1996 |
Gartel AL, Serfas MS, Tyner AL. p21 - Negative regulator of the cell cycle Proceedings of the Society For Experimental Biology and Medicine. 213: 138-149. PMID 8931660 DOI: 10.3181/00379727-213-44046 |
0.313 |
|
1996 |
Gartel AL, Serfas MS, Gartel M, Goufman E, Wu GS, El-Deiry WS, Tyner AL. p21 (WAF1/CIP1) expression is induced in newly nondividing cells in diverse epithelia and during differentiation of the Caco-2 intestinal cell line Experimental Cell Research. 227: 171-181. PMID 8831553 DOI: 10.1006/Excr.1996.0264 |
0.305 |
|
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