Year |
Citation |
Score |
2016 |
Mathur PS, Gierut JJ, Guzman G, Xie H, Xicola RM, Llor X, Chastkofsky MI, Perekatt AO, Tyner AL. Kinase-Dependent and Independent Roles for PTK6 in Colon Cancer. Molecular Cancer Research : McR. PMID 26983689 DOI: 10.1158/1541-7786.Mcr-15-0450 |
0.781 |
|
2015 |
Gierut JJ, Wood LB, Lau KS, Lin YJ, Genetti C, Samatar AA, Lauffenburger DA, Haigis KM. Network-level effects of kinase inhibitors modulate TNF-α-induced apoptosis in the intestinal epithelium. Science Signaling. 8: ra129. PMID 26671150 DOI: 10.1126/Scisignal.Aac7235 |
0.303 |
|
2012 |
Zheng Y, Gierut J, Wang Z, Miao J, Asara JM, Tyner AL. Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT. Oncogene. 32: 4304-12. PMID 23027128 DOI: 10.1038/Onc.2012.427 |
0.745 |
|
2012 |
Gierut JJ, Mathur PS, Bie W, Han J, Tyner AL. Targeting protein tyrosine kinase 6 enhances apoptosis of colon cancer cells following DNA damage. Molecular Cancer Therapeutics. 11: 2311-20. PMID 22989419 DOI: 10.1158/1535-7163.Mct-12-0009 |
0.746 |
|
2012 |
Gierut J, Zheng Y, Tyner AL. Su1833 Identification and Characterization of Novel Protein Tyrosine Kinase 6 Substrates and Associated Proteins in Intestinal Cells Gastroenterology. 142: S-515. DOI: 10.1016/S0016-5085(12)61974-X |
0.717 |
|
2011 |
Gierut J, Zheng Y, Bie W, Carroll RE, Ball-Kell S, Haegebarth A, Tyner AL. Disruption of the mouse protein tyrosine kinase 6 gene prevents STAT3 activation and confers resistance to azoxymethane. Gastroenterology. 141: 1371-80, 1380.e1-2. PMID 21741923 DOI: 10.1053/J.Gastro.2011.06.071 |
0.762 |
|
2011 |
Gierut J, Zheng Y, Bie W, Tyner AL. Protein Tyrosine Kinase 6 Promotes STAT3 Activation and Colon Tumorigenesis In Vivo Gastroenterology. 140: S-821. DOI: 10.1016/S0016-5085(11)63401-X |
0.739 |
|
2011 |
Gierut J, Perekatt AO, Tyner AL. Protein Tyrosine Kinase 6 Expression is Regulated by p53-Dependent and Independent Mechanisms in Response to DNA-Damage Gastroenterology. 140: S-144. DOI: 10.1016/S0016-5085(11)60586-6 |
0.774 |
|
2010 |
Palka-Hamblin HL, Gierut JJ, Bie W, Brauer PM, Zheng Y, Asara JM, Tyner AL. Identification of beta-catenin as a target of the intracellular tyrosine kinase PTK6. Journal of Cell Science. 123: 236-45. PMID 20026641 DOI: 10.1242/Jcs.053264 |
0.742 |
|
2010 |
Gierut J, Perekatt AO, Han J, Tyner AL. W1748 Protein Tyrosine Kinase 6 Promotes Apoptosis of p53−/− Human Colon Cancer Cells After DNA-Damage Gastroenterology. 138: S-732. DOI: 10.1016/S0016-5085(10)63368-9 |
0.786 |
|
2009 |
Haegebarth A, Perekatt AO, Bie W, Gierut JJ, Tyner AL. Induction of protein tyrosine kinase 6 in mouse intestinal crypt epithelial cells promotes DNA damage-induced apoptosis. Gastroenterology. 137: 945-54. PMID 19501589 DOI: 10.1053/J.Gastro.2009.05.054 |
0.79 |
|
2009 |
Gierut J, Bie W, Zheng Y, Tyner AL. W1935 The Intracellular Tyrosine Kinase PTK6 Is Induced in Select Crypt Cells in the Colon After Azoxymethane Treatment Gastroenterology. 136: A-757. DOI: 10.1016/S0016-5085(09)63494-6 |
0.723 |
|
2009 |
Gierut J, Perekatt AO, Tyner AL. M1611 The Intracellular Tyrosine Kinase PTK6 Regulates Protein Phosphatase 2a in Intestinal Epithelial Cells Gastroenterology. 136: A-394. DOI: 10.1016/S0016-5085(09)61811-4 |
0.774 |
|
2009 |
Perekatt AO, Gierut J, Zheng Y, Tyner AL. S1994 The Intracellular Tyrosine Kinase PTK6 Plays Distinct Roles in Colon and Breast Cancer Cell Lines Gastroenterology. 136: A-309. DOI: 10.1016/S0016-5085(09)61410-4 |
0.76 |
|
2008 |
PALKAHAMBLIN H, GIERUT J, BRAUER P, ZHENG Y, TYNER A. M1646 The Intracellular Tyrosine Kinase PTK6 Phosphorylates Beta-Catenin and Negatively Regulates Beta-Catenin/Tcf Transcription Gastroenterology. 134: A-389-A-389. DOI: 10.1016/S0016-5085(08)61816-8 |
0.759 |
|
2008 |
Gierut J, Bie W, Haegebarth A, Carroll RE, Tyner AL. M1629 The Role of the Intracellular Tyrosine Kinase PTK6 in Azoxymethane-Induced Colorectal Carcinogenesis Gastroenterology. 134: A-385. DOI: 10.1016/S0016-5085(08)61799-0 |
0.705 |
|
2006 |
Radhakrishnan SK, Gierut J, Gartel AL. Multiple alternate p21 transcripts are regulated by p53 in human cells Oncogene. 25: 1812-1815. PMID 16261158 DOI: 10.1038/Sj.Onc.1209195 |
0.328 |
|
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