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Aaron C. Hinken, Ph.D. - Publications

Affiliations: 
2005 University of Missouri - Columbia, Columbia, MO, United States 
Area:
Animal Physiology Biology, Recreation, Medicine and Surgery
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Cheng AJ, Hwee DT, Kim LH, Durham N, Yang HT, Hinken AC, Kennedy AR, Terjung RL, Jasper JR, Malik FI, Westerblad H. Fast skeletal muscle troponin activator CK-2066260 increases fatigue resistance by reducing the energetic cost of muscle contraction. The Journal of Physiology. PMID 31246276 DOI: 10.1113/Jp278235  0.445
2018 Collibee SE, Bergnes G, Muci A, Browne WF, Garard M, Hinken AC, Russell AJ, Suehiro I, Hartman J, Kawas R, Lu PP, Lee KH, Marquez D, Tomlinson M, Xu D, et al. Discovery of , the First Direct Fast Skeletal Muscle Troponin Activator. Acs Medicinal Chemistry Letters. 9: 354-358. PMID 29670700 DOI: 10.1021/Acsmedchemlett.7B00546  0.309
2016 Hwee DT, Cheng AJ, Hartman JJ, Hinken AC, Lee K, Durham N, Russell AJ, Malik FI, Westerblad H, Jasper JR. The Ca(2+) sensitizer CK-2066260 increases myofibrillar Ca(2+) sensitivity and submaximal force selectively in fast skeletal muscle. The Journal of Physiology. PMID 27869319 DOI: 10.1113/Jp273248  0.465
2014 Hwee DT, Kennedy A, Ryans J, Russell AJ, Jia Z, Hinken AC, Morgans DJ, Malik FI, Jasper JR. Fast skeletal muscle troponin activator tirasemtiv increases muscle function and performance in the B6SJL-SOD1G93A ALS mouse model. Plos One. 9: e96921. PMID 24805850 DOI: 10.1371/Journal.Pone.0096921  0.393
2014 Alves ML, Dias FA, Gaffin RD, Simon JN, Montminy EM, Biesiadecki BJ, Hinken AC, Warren CM, Utter MS, Davis RT, Sadayappan S, Robbins J, Wieczorek DF, Solaro RJ, Wolska BM. Desensitization of myofilaments to Ca2+ as a therapeutic target for hypertrophic cardiomyopathy with mutations in thin filament proteins. Circulation. Cardiovascular Genetics. 7: 132-43. PMID 24585742 DOI: 10.1161/Circgenetics.113.000324  0.339
2014 Fornaro M, Hinken AC, Needle S, Hu E, Trendelenburg AU, Mayer A, Rosenstiel A, Chang C, Meier V, Billin AN, Becherer JD, Brace AD, Evans WJ, Glass DJ, Russell AJ. Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells. American Journal of Physiology. Endocrinology and Metabolism. 306: E150-6. PMID 24253050 DOI: 10.1152/Ajpendo.00408.2013  0.32
2013 Henze M, Patrick SE, Hinken A, Scruggs SB, Goldspink P, de Tombe PP, Kobayashi M, Ping P, Kobayashi T, Solaro RJ. New insights into the functional significance of the acidic region of the unique N-terminal extension of cardiac troponin I. Biochimica Et Biophysica Acta. 1833: 823-32. PMID 22940544 DOI: 10.1016/J.Bbamcr.2012.08.012  0.431
2012 Hinken AC, Hanft LM, Scruggs SB, Sadayappan S, Robbins J, Solaro RJ, McDonald KS. Protein kinase C depresses cardiac myocyte power output and attenuates myofilament responses induced by protein kinase A. Journal of Muscle Research and Cell Motility. 33: 439-48. PMID 22527640 DOI: 10.1007/S10974-012-9294-9  0.626
2012 Russell AJ, Hartman JJ, Hinken AC, Muci AR, Kawas R, Driscoll L, Godinez G, Lee KH, Marquez D, Browne WF, Chen MM, Clarke D, Collibee SE, Garard M, Hansen R, et al. Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases. Nature Medicine. 18: 452-5. PMID 22344294 DOI: 10.1038/Nm.2618  0.386
2012 Malik F, Russell A, Pannirselvam M, Hinken A, Thomsen K, Ardiana A, Godinez G, Jia Z, Saikali K, Chen M, Morgans D, Jasper J. The Fast Skeletal Troponin Activator, CK-2017357, Increases Muscle Function and Survival in SOD1 (G93A) Mice; a Model of ALS (P05.169) Neurology. 78. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P05.169  0.334
2011 Sheehan KA, Arteaga GM, Hinken AC, Dias FA, Ribeiro C, Wieczorek DF, Solaro RJ, Wolska BM. Functional effects of a tropomyosin mutation linked to FHC contribute to maladaptation during acidosis. Journal of Molecular and Cellular Cardiology. 50: 442-50. PMID 21047515 DOI: 10.1016/J.Yjmcc.2010.10.032  0.446
2010 Avner BS, Hinken AC, Yuan C, Solaro RJ. H2O2 alters rat cardiac sarcomere function and protein phosphorylation through redox signaling. American Journal of Physiology. Heart and Circulatory Physiology. 299: H723-30. PMID 20562337 DOI: 10.1152/Ajpheart.00050.2010  0.387
2010 Lu QW, Hinken AC, Patrick SE, Solaro RJ, Kobayashi T. Phosphorylation of cardiac troponin I at protein kinase C site threonine 144 depresses cooperative activation of thin filaments. The Journal of Biological Chemistry. 285: 11810-7. PMID 20164197 DOI: 10.1074/Jbc.M109.055657  0.439
2010 Hinken A, Driscoll L, Lee K, Hartman JJ, Marquez D, Hansen R, Muci A, Morgan B, Malik F, Russell AJ. The Fast Skeletal Troponin Activator, CK-1909178 Reduces Muscle Fatigue in a Model of Peripheral Artery Disease in Situ Biophysical Journal. 98: 543a. DOI: 10.1016/J.Bpj.2009.12.2945  0.413
2009 Engel PL, Hinken A, Solaro RJ. Differential effects of phosphorylation of regions of troponin I in modifying cooperative activation of cardiac thin filaments. Journal of Molecular and Cellular Cardiology. 47: 359-64. PMID 19426736 DOI: 10.1016/J.Yjmcc.2009.04.016  0.431
2009 Scruggs SB, Hinken AC, Thawornkaiwong A, Robbins J, Walker LA, de Tombe PP, Geenen DL, Buttrick PM, Solaro RJ. Ablation of ventricular myosin regulatory light chain phosphorylation in mice causes cardiac dysfunction in situ and affects neighboring myofilament protein phosphorylation. The Journal of Biological Chemistry. 284: 5097-106. PMID 19106098 DOI: 10.1074/Jbc.M807414200  0.463
2009 Wilder T, Hinken AC, Solaro RJ. Altered Myofilament Targeting with Differential PKCδ Activation Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.2582  0.405
2008 Sumandea MP, Rybin VO, Hinken AC, Wang C, Kobayashi T, Harleton E, Sievert G, Balke CW, Feinmark SJ, Solaro RJ, Steinberg SF. Tyrosine phosphorylation modifies protein kinase C δ-dependent phosphorylation of cardiac troponin I Journal of Biological Chemistry. 283: 22680-22689. PMID 18550549 DOI: 10.1074/Jbc.M802396200  0.38
2007 Hinken AC, Solaro RJ. A dominant role of cardiac molecular motors in the intrinsic regulation of ventricular ejection and relaxation. Physiology (Bethesda, Md.). 22: 73-80. PMID 17420299 DOI: 10.1152/Physiol.00043.2006  0.319
2006 Hinken AC, Korte FS, McDonald KS. Porcine cardiac myocyte power output is increased after chronic exercise training. Journal of Applied Physiology (Bethesda, Md. : 1985). 101: 40-6. PMID 16565350 DOI: 10.1152/Japplphysiol.00798.2005  0.596
2006 Hinken AC, McDonald KS. Beta-myosin heavy chain myocytes are more resistant to changes in power output induced by ischemic conditions. American Journal of Physiology. Heart and Circulatory Physiology. 290: H869-77. PMID 16172167 DOI: 10.1152/Ajpheart.00221.2005  0.571
2004 Hinken AC, McDonald KS. Inorganic phosphate speeds loaded shortening in rat skinned cardiac myocytes. American Journal of Physiology. Cell Physiology. 287: C500-7. PMID 15084471 DOI: 10.1152/Ajpcell.00049.2004  0.596
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