| Year |
Citation |
Score |
| 2020 |
Diffenderfer ES, Verginadis II, Kim MM, Shoniyozov K, Velalopoulou A, Goia D, Putt M, Hagan S, Avery S, Teo K, Zou W, Lin A, Swisher-McClure S, Koch C, Kennedy AR, et al. Design, Implementation, and in Vivo Validation of a Novel Proton FLASH Radiation Therapy System. International Journal of Radiation Oncology, Biology, Physics. 106: 440-448. PMID 31928642 DOI: 10.1016/J.Ijrobp.2019.10.049 |
0.362 |
|
| 2018 |
Koch CJ. A Two-Component Assay for Hypoxia Incorporating Long-Term Nitroreduction and Short-Term DNA-Damage Allows Differentiation of the Three Hypoxia Sub-types. Radiation Research. PMID 29746214 DOI: 10.1667/Rr15029.1 |
0.413 |
|
| 2016 |
Pietrofesa RA, Velalopoulou A, Lehman SL, Arguiri E, Solomides P, Koch CJ, Mishra OP, Koumenis C, Goodwin TJ, Christofidou-Solomidou M. Novel Double-Hit Model of Radiation and Hyperoxia-Induced Oxidative Cell Damage Relevant to Space Travel. International Journal of Molecular Sciences. 17. PMID 27322243 DOI: 10.3390/Ijms17060953 |
0.354 |
|
| 2015 |
Lao Z, Kelly CJ, Yang XY, Jenkins WT, Toorens E, Ganguly T, Evans SM, Koch CJ. Improved Methods to Generate Spheroid Cultures from Tumor Cells, Tumor Cells & Fibroblasts or Tumor-Fragments: Microenvironment, Microvesicles and MiRNA. Plos One. 10: e0133895. PMID 26208323 DOI: 10.1371/Journal.Pone.0133895 |
0.379 |
|
| 2015 |
Koch CJ, Evans SM. Optimizing hypoxia detection and treatment strategies. Seminars in Nuclear Medicine. 45: 163-76. PMID 25704388 DOI: 10.1053/J.Semnuclmed.2014.10.004 |
0.391 |
|
| 2015 |
Chang Q, Ornatsky OI, Koch CJ, Chaudary N, Marie-Egyptienne DT, Hill RP, Tanner SD, Hedley DW. Single-cell measurement of the uptake, intratumoral distribution and cell cycle effects of cisplatin using mass cytometry. International Journal of Cancer. Journal International Du Cancer. 136: 1202-9. PMID 25042623 DOI: 10.1002/Ijc.29074 |
0.372 |
|
| 2014 |
Koch CJ, Lustig RA, Yang XY, Jenkins WT, Wolf RL, Martinez-Lage M, Desai A, Williams D, Evans SM. Microvesicles as a Biomarker for Tumor Progression versus Treatment Effect in Radiation/Temozolomide-Treated Glioblastoma Patients. Translational Oncology. 7: 752-8. PMID 25500085 DOI: 10.1016/J.Tranon.2014.10.004 |
0.336 |
|
| 2014 |
Regter S, Hedayati M, Zhang Y, Zhou H, Dalrymple S, Koch CJ, Isaacs JT, DeWeese TL. Androgen withdrawal fails to induce detectable tissue hypoxia in the rat prostate. The Prostate. 74: 805-10. PMID 24677180 DOI: 10.1002/Pros.22803 |
0.321 |
|
| 2013 |
Cerniglia GJ, Daurio N, Gallagher-Colombo SM, Busch TM, Tuttle SW, Koch CJ, Lin A, Koumenis C, Maity A. Abstract 1037: Agents that target the PI3K/mTOR pathway decrease oxygen consumption, reduce tumor hypoxia and improve radiation response in solid tumors. Cancer Research. 73: 1037-1037. DOI: 10.1158/1538-7445.Am2013-1037 |
0.415 |
|
| 2013 |
Maity A, Cerniglia G, Daurio N, Gallagher-Colombo S, Busch T, Tuttle S, Koch C, Lin A, Koumenis C. Targeting the PI3K/mTOR Pathway Reduces Tumor Hypoxia and Decreases Oxygen Consumption International Journal of Radiation Oncology*Biology*Physics. 87: S170. DOI: 10.1016/J.Ijrobp.2013.06.439 |
0.353 |
|
| 2011 |
Williams JR, Zhang Y, Zhou H, Gridley DS, Koch CJ, Slater JM, Dicello JF, Little JB. Sequentially-induced responses define tumour cell radiosensitivity. International Journal of Radiation Biology. 87: 628-43. PMID 21501033 DOI: 10.3109/09553002.2011.568573 |
0.32 |
|
| 2011 |
Marotta D, Karar J, Jenkins WT, Kumanova M, Jenkins KW, Tobias JW, Baldwin D, Hatzigeorgiou A, Alexiou P, Evans SM, Alarcon R, Maity A, Koch C, Koumenis C. In vivo profiling of hypoxic gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection. Cancer Research. 71: 779-89. PMID 21266355 DOI: 10.1158/0008-5472.Can-10-3061 |
0.37 |
|
| 2011 |
Karar J, Marotta D, Jenkins WT, Kumanova M, Jenkins K, Tobias JW, Baldwin D, Hatzigeorgiou A, Alexiou P, Evans SM, Alarcon R, Koch C, Maity A, Koumenis C. Abstract 5004:In vivoprofiling of hypoxic mRNA and miRNA expression in gliomas and head and neck tumors Cancer Research. 71: 5004-5004. DOI: 10.1158/1538-7445.Am2011-5004 |
0.344 |
|
| 2010 |
Williams JR, Zhang Y, Zhou H, Gridley DS, Koch CJ, Dicello JF, Slater JM, Little JB. Tumor response to radiotherapy is dependent on genotype-associated mechanisms in vitro and in vivo. Radiation Oncology (London, England). 5: 71. PMID 20704711 DOI: 10.1186/1748-717X-5-71 |
0.374 |
|
| 2010 |
Lee SC, Poptani H, Pickup S, Jenkins WT, Kim S, Koch CJ, Delikatny EJ, Glickson JD. Early detection of radiation therapy response in non-Hodgkin's lymphoma xenografts by in vivo 1H magnetic resonance spectroscopy and imaging. Nmr in Biomedicine. 23: 624-32. PMID 20661875 DOI: 10.1002/Nbm.1505 |
0.314 |
|
| 2010 |
Koch CJ, Scheuermann JS, Divgi C, Judy KD, Kachur AV, Freifelder R, Reddin JS, Karp J, Stubbs JB, Hahn SM, Driesbaugh J, Smith D, Prendergast S, Evans SM. Biodistribution and dosimetry of (18)F-EF5 in cancer patients with preliminary comparison of (18)F-EF5 uptake versus EF5 binding in human glioblastoma. European Journal of Nuclear Medicine and Molecular Imaging. 37: 2048-59. PMID 20585774 DOI: 10.1007/S00259-010-1517-Y |
0.316 |
|
| 2010 |
Evans SM, Jenkins KW, Chen HI, Jenkins WT, Judy KD, Hwang WT, Lustig RA, Judkins AR, Grady MS, Hahn SM, Koch CJ. The Relationship among Hypoxia, Proliferation, and Outcome in Patients with De Novo Glioblastoma: A Pilot Study. Translational Oncology. 3: 160-9. PMID 20563257 DOI: 10.1593/Tlo.09265 |
0.341 |
|
| 2010 |
Koch CJ. Abstract SY34-04: Do we need to know what pO2 hypoxia is Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Sy34-04 |
0.387 |
|
| 2010 |
Wang J, Patel R, Ferry D, Hay MP, Koch CJ, Wilson WR. Abstract 2272: Comparison of bioreductive metabolism of tirapazamine, its second generation analogue SN 30000 and hypoxia imaging agent EF5 in human tumor cell lines Cancer Research. 70: 2272-2272. DOI: 10.1158/1538-7445.Am10-2272 |
0.364 |
|
| 2009 |
Koch CJ, Shuman AL, Jenkins WT, Kachur AV, Karp JS, Freifelder R, Dolbier WR, Evans SM. The radiation response of cells from 9L gliosarcoma tumours is correlated with [F18]-EF5 uptake. International Journal of Radiation Biology. 85: 1137-47. PMID 19995239 DOI: 10.3109/09553000903242172 |
0.324 |
|
| 2009 |
Cerniglia GJ, Pore N, Tsai JH, Schultz S, Mick R, Choe R, Xing X, Durduran T, Yodh AG, Evans SM, Koch CJ, Hahn SM, Quon H, Sehgal CM, Lee WM, et al. Epidermal growth factor receptor inhibition modulates the microenvironment by vascular normalization to improve chemotherapy and radiotherapy efficacy. Plos One. 4: e6539. PMID 19657384 DOI: 10.1371/Journal.Pone.0006539 |
0.383 |
|
| 2009 |
Chan N, Koch CJ, Bristow RG. Tumor hypoxia as a modifier of DNA strand break and cross-link repair. Current Molecular Medicine. 9: 401-10. PMID 19519397 DOI: 10.2174/156652409788167050 |
0.328 |
|
| 2008 |
Evans SM, Jenkins KW, Jenkins WT, Dilling T, Judy KD, Schrlau A, Judkins A, Hahn SM, Koch CJ. Imaging and analytical methods as applied to the evaluation of vasculature and hypoxia in human brain tumors Radiation Research. 170: 677-690. PMID 19138031 DOI: 10.1667/Rr1207.1 |
0.368 |
|
| 2008 |
Williams JR, Zhang Y, Zhou H, Gridley DS, Koch CJ, Slater JM, Little JB. Overview of Radiosensitivity of Human Tumor Cells to Low-Dose-Rate Irradiation International Journal of Radiation Oncology Biology Physics. 72: 909-917. PMID 19014780 DOI: 10.1016/J.Ijrobp.2008.06.1928 |
0.351 |
|
| 2008 |
Koch CJ. Importance of antibody concentration in the assessment of cellular hypoxia by flow cytometry: EF5 and pimonidazole. Radiation Research. 169: 677-88. PMID 18494550 DOI: 10.1667/Rr1305.1 |
0.31 |
|
| 2008 |
Boutin AT, Weidemann A, Fu Z, Mesropian L, Gradin K, Jamora C, Wiesener M, Eckardt KU, Koch CJ, Ellies LG, Haddad G, Haase VH, Simon MC, Poellinger L, Powell FL, et al. Epidermal sensing of oxygen is essential for systemic hypoxic response. Cell. 133: 223-34. PMID 18423195 DOI: 10.1016/J.Cell.2008.02.038 |
0.316 |
|
| 2008 |
Williams JR, Zhang Y, Zhou H, Gridley DS, Koch CJ, Russell J, Slater JS, Little JB. A quantitative overview of radiosensitivity of human tumor cells across histological type and TP53 status International Journal of Radiation Biology. 84: 253-264. PMID 18386191 DOI: 10.1080/09553000801953342 |
0.348 |
|
| 2008 |
Williams JR, Zhang Y, Zhou H, Russell J, Gridley DS, Koch CJ, Little JB. Genotype-dependent radiosensitivity: Clonogenic survival, apoptosis and cell-cycle redistribution International Journal of Radiation Biology. 84: 151-164. PMID 18246483 DOI: 10.1080/09553000701797021 |
0.316 |
|
| 2008 |
Pore N, Cerniglia G, Tsai J, Koch C, Evans S, Sehgal C, Lee W, Maity A. Effects of the EGFR Inhibitor Erlotinib on Tumor Microenvironment: Implications for Therapy International Journal of Radiation Oncology Biology Physics. 72. DOI: 10.1016/J.Ijrobp.2008.06.904 |
0.41 |
|
| 2007 |
Evans SM, Du KL, Chalian AA, Mick R, Zhang PJ, Hahn SM, Quon H, Lustig R, Weinstein GS, Koch CJ. Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to patient outcome. International Journal of Radiation Oncology, Biology, Physics. 69: 1024-31. PMID 17967299 DOI: 10.1016/J.Ijrobp.2007.04.067 |
0.379 |
|
| 2007 |
Tuttle SW, Maity A, Oprysko PR, Kachur AV, Ayene IS, Biaglow JE, Koch CJ. Detection of reactive oxygen species via endogenous oxidative pentose phosphate cycle activity in response to oxygen concentration: implications for the mechanism of HIF-1alpha stabilization under moderate hypoxia. The Journal of Biological Chemistry. 282: 36790-6. PMID 17666400 DOI: 10.1074/Jbc.M700327200 |
0.358 |
|
| 2007 |
Wang HW, Finlay JC, Lee K, Zhu TC, Putt ME, Glatstein E, Koch CJ, Evans SM, Hahn SM, Busch TM, Yodh AG. Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis. Journal of Biomedical Optics. 12: 034023. PMID 17614731 DOI: 10.1117/1.2743082 |
0.388 |
|
| 2007 |
Williams JR, Zhang Y, Russell J, Koch C, Little JB. Human tumor cells segregate into radiosensitivity groups that associate with ATM and TP53 status Acta Oncologica. 46: 628-638. PMID 17562439 DOI: 10.1080/02841860601080407 |
0.329 |
|
| 2007 |
Lee DC, Adams CS, Albert TJ, Shapiro IM, Evans SM, Koch CJ. In situ oxygen utilization in the rat intervertebral disc. Journal of Anatomy. 210: 294-303. PMID 17331178 DOI: 10.1111/J.1469-7580.2007.00692.X |
0.367 |
|
| 2006 |
Pore N, Gupta AK, Cerniglia GJ, Jiang Z, Bernhard EJ, Evans SM, Koch CJ, Hahn SM, Maity A. Nelfinavir down-regulates hypoxia-inducible factor 1alpha and VEGF expression and increases tumor oxygenation: implications for radiotherapy. Cancer Research. 66: 9252-9. PMID 16982770 DOI: 10.1158/0008-5472.Can-06-1239 |
0.383 |
|
| 2006 |
Evans SM, Schrlau AE, Chalian AA, Zhang P, Koch CJ. Oxygen levels in normal and previously irradiated human skin as assessed by EF5 binding. The Journal of Investigative Dermatology. 126: 2596-606. PMID 16810299 DOI: 10.1038/Sj.Jid.5700451 |
0.347 |
|
| 2006 |
Biaglow JE, Ayene IS, Tuttle SW, Koch CJ, Donahue J, Mieyal JJ. Role of vicinal protein thiols in radiation and cytotoxic responses. Radiation Research. 165: 307-17. PMID 16494519 DOI: 10.1667/Rr3505.1 |
0.318 |
|
| 2006 |
Wang HW, Lee K, Yodh AG, Finlay JC, Zhu TC, Busch TM, Koch CJ, Evans SM, Hahn S. Association of in-vivo and ex-vivo measurements of tissue oxygenation and photosensitizer concentration in patients with intraperitoneal caracinomatosis Biosilico. DOI: 10.1364/Bio.2006.Sd3 |
0.315 |
|
| 2006 |
Evans SM, Jenkins K, Dilling T, Jenkins WT, Koch CJ. 190 Microenvironment of brain tumors: Hypoxia, proliferation and vasculature Radiotherapy and Oncology. 78. DOI: 10.1016/S0167-8140(06)80667-5 |
0.321 |
|
| 2006 |
Pore N, Gupta AK, Cerniglia GJ, Jiang Z, Bernhard EJ, Evans SM, Koch CJ, Hahn SM, Maity A. 215 : Nelfinavir Downregulates HIF-1alpha and VEGF expression and Increases Tumor Oxygenation: Implications for Radiotherapy International Journal of Radiation Oncology Biology Physics. 66. DOI: 10.1016/J.Ijrobp.2006.07.248 |
0.35 |
|
| 2005 |
Ayene IS, Ford LP, Koch CJ. Ku protein targeting by Ku70 small interfering RNA enhances human cancer cell response to topoisomerase II inhibitor and gamma radiation. Molecular Cancer Therapeutics. 4: 529-36. PMID 15827325 DOI: 10.1158/1535-7163.Mct-04-0130 |
0.352 |
|
| 2005 |
Shi Y, Lee CS, Wu J, Koch CJ, Thom SR, Maity A, Bernhard EJ. Effects of hyperbaric oxygen exposure on experimental head and neck tumor growth, oxygenation, and vasculature. Head & Neck. 27: 362-9. PMID 15818558 DOI: 10.1002/Hed.20169 |
0.383 |
|
| 2005 |
Grimberg A, Coleman CM, Burns TF, Himelstein BP, Koch CJ, Cohen P, El-Deiry WS. p53-Dependent and p53-independent induction of insulin-like growth factor binding protein-3 by deoxyribonucleic acid damage and hypoxia. The Journal of Clinical Endocrinology and Metabolism. 90: 3568-74. PMID 15769996 DOI: 10.1210/Jc.2004-1213 |
0.356 |
|
| 2005 |
Shi Y, Wu J, Mick R, Cerniglia GJ, Cohen-Jonathan E, Rhim JS, Koch CJ, Bernhard EJ. Farnesyltransferase inhibitor effects on prostate tumor micro-environment and radiation survival. The Prostate. 62: 69-82. PMID 15389805 DOI: 10.1002/Pros.20122 |
0.329 |
|
| 2005 |
Du KL, Chalian AA, Zhang PJ, Hahn SM, Quon H, Weinstein GS, Koch CJ, Evans SM. The Prognostic Role of Hypoxia in Head and Neck Squamous Cell Tumors, as Measured by EF5, is Influenced by EF5 Binding Patterns International Journal of Radiation Oncology Biology Physics. 63. DOI: 10.1016/J.Ijrobp.2005.07.814 |
0.345 |
|
| 2005 |
Pore N, Jiang Z, McGarry M, Gupta A, Cerniglia G, Shulman L, Cash-Mason T, Koch C, Quon H, Evans SM, Maity A. Gefitinib (ZD1839) Decreases Vascular Endothelial Growth Factor (VEGF) Expression by Hypoxia-Inducible Factor (HIF)-1 Independent and Dependent Mechanisms and Increases Tumor Oxygenation International Journal of Radiation Oncology Biology Physics. 63. DOI: 10.1016/J.Ijrobp.2005.07.232 |
0.336 |
|
| 2004 |
Evans SM, Judy KD, Dunphy I, Jenkins WT, Hwang WT, Nelson PT, Lustig RA, Jenkins K, Magarelli DP, Hahn SM, Collins RA, Grady MS, Koch CJ. Hypoxia is important in the biology and aggression of human glial brain tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 8177-84. PMID 15623592 DOI: 10.1158/1078-0432.Ccr-04-1081 |
0.376 |
|
| 2004 |
Acs G, Chen M, Xu X, Acs P, Verma A, Koch CJ. Autocrine erythropoietin signaling inhibits hypoxia-induced apoptosis in human breast carcinoma cells. Cancer Letters. 214: 243-51. PMID 15363551 DOI: 10.1016/J.Canlet.2004.04.027 |
0.379 |
|
| 2004 |
Busch TM, Hahn SM, Wileyto EP, Koch CJ, Fraker DL, Zhang P, Putt M, Gleason K, Shin DB, Emanuele MJ, Jenkins K, Glatstein E, Evans SM. Hypoxia and Photofrin uptake in the intraperitoneal carcinomatosis and sarcomatosis of photodynamic therapy patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 4630-8. PMID 15269134 DOI: 10.1158/1078-0432.Ccr-04-0359 |
0.363 |
|
| 2004 |
Kaufman B, Scharf O, Arbeit J, Ashcroft M, Brown JM, Bruick RK, Chapman JD, Evans SM, Giaccia AJ, Harris AL, Huang E, Johnson R, Kaelin W, Koch CJ, Maxwell P, et al. Proceedings of the Oxygen Homeostasis/Hypoxia Meeting. Cancer Research. 64: 3350-6. PMID 15126380 DOI: 10.1158/0008-5472.Can-03-2611 |
0.322 |
|
| 2004 |
Pan Y, Oprysko PR, Asham AM, Koch CJ, Simon MC. p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment. Oncogene. 23: 4975-83. PMID 15107830 DOI: 10.1038/Sj.Onc.1207657 |
0.332 |
|
| 2004 |
Evans SM, Judy KD, Dunphy I, Jenkins WT, Nelson PT, Collins R, Wileyto EP, Jenkins K, Hahn SM, Stevens CW, Judkins AR, Phillips P, Geoerger B, Koch CJ. Comparative measurements of hypoxia in human brain tumors using needle electrodes and EF5 binding. Cancer Research. 64: 1886-92. PMID 14996753 DOI: 10.1158/0008-5472.Can-03-2424 |
0.388 |
|
| 2003 |
Evans SM, Koch CJ. Prognostic significance of tumor oxygenation in humans. Cancer Letters. 195: 1-16. PMID 12767506 DOI: 10.1016/S0304-3835(03)00012-0 |
0.412 |
|
| 2003 |
Mahy P, De Bast M, Gallez B, Gueulette J, Koch CJ, Scalliet P, Grégoire V. In vivo colocalization of 2-nitroimidazole EF5 fluorescence intensity and electron paramagnetic resonance oximetry in mouse tumors. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 67: 53-61. PMID 12758240 DOI: 10.1016/S0167-8140(03)00028-8 |
0.32 |
|
| 2003 |
Biaglow JE, Ayene IS, Koch CJ, Donahue J, Stamato TD, Mieyal JJ, Tuttle SW. Radiation response of cells during altered protein thiol redox. Radiation Research. 159: 484-94. PMID 12643793 DOI: 10.1667/0033-7587(2003)159[0484:Rrocda]2.0.Co;2 |
0.347 |
|
| 2003 |
Koch CJ, Evans SM. Non-invasive PET and SPECT imaging of tissue hypoxia using isotopically labeled 2-nitroimidazoles. Advances in Experimental Medicine and Biology. 510: 285-92. PMID 12580442 DOI: 10.1007/978-1-4615-0205-0_47 |
0.32 |
|
| 2003 |
Busch TM, Wileyto EP, Evans SM, Koch CJ. Quantitative spatial analysis of hypoxia and vascular perfusion in tumor sections. Advances in Experimental Medicine and Biology. 510: 37-43. PMID 12580402 DOI: 10.1007/978-1-4615-0205-0_7 |
0.394 |
|
| 2002 |
Evans SM, Lew R, Kochman ML, Wileyto EP, Baum E, Safford KM, Koch CJ. Human esophageal cancer is distinguished from adjacent esophageal tissue by tissue cysteine concentrations Digestive Diseases and Sciences. 47: 2743-2750. PMID 12498295 DOI: 10.1023/A:1021009322843 |
0.324 |
|
| 2002 |
Koch CJ, Oprysko PR, Shuman AL, Jenkins WT, Brandt G, Evans SM. Radiosensitization of hypoxic tumor cells by dodecafluoropentane: a gas-phase perfluorochemical emulsion. Cancer Research. 62: 3626-9. PMID 12097264 |
0.313 |
|
| 2002 |
Nadal-Desbarats L, Poptani H, Oprysko P, Jenkins WT, Busch TM, Nelson DS, Glickson JD, Koch CJ, Evans SM. Effects of hyperglycemia on oxygenation, radiosensitivity and bioenergetic status of subcutaneous RIF-1 tumors. International Journal of Oncology. 21: 103-10. PMID 12063556 DOI: 10.3892/Ijo.21.1.103 |
0.381 |
|
| 2002 |
Kajino H, Goldbarg S, Roman C, Liu BM, Mauray F, Chen YQ, Takahashi Y, Koch CJ, Clyman RI. Vasa vasorum hypoperfusion is responsible for medial hypoxia and anatomic remodeling in the newborn lamb ductus arteriosus. Pediatric Research. 51: 228-35. PMID 11809919 DOI: 10.1203/00006450-200202000-00017 |
0.307 |
|
| 2001 |
Ziemer LS, Koch CJ, Maity A, Magarelli DP, Horan AM, Evans SM. Hypoxia and VEGF mRNA expression in human tumors Neoplasia. 3: 500-508. PMID 11774032 DOI: 10.1038/Sj.Neo.7900195 |
0.363 |
|
| 2001 |
Koch CJ, Hahn SM, Rockwell K. J, Covey JM, McKenna WG, Evans SM. Pharmacokinetics of EF5 [2-(2-nitro-1-H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide] in human patients: Implications for hypoxia measurements in vivo by 2-nitroimidazoles Cancer Chemotherapy and Pharmacology. 48: 177-187. PMID 11592338 DOI: 10.1007/S002800100324 |
0.316 |
|
| 2001 |
Evans SM, Hahn SM, Magarelli DP, Koch CJ. Hypoxic heterogeneity in human tumors: EF5 binding, vasculature, necrosis, and proliferation American Journal of Clinical Oncology: Cancer Clinical Trials. 24: 467-472. PMID 11586098 DOI: 10.1097/00000421-200110000-00011 |
0.374 |
|
| 2001 |
Horan AD, Koch CJ. The Km for radiosensitization of human tumor cells by oxygen is much greater than 3 mmHg and is further increased by elevated levels of cysteine Radiation Research. 156: 388-398. PMID 11554850 DOI: 10.1667/0033-7587(2001)156[0388:Tkmfro]2.0.Co;2 |
0.424 |
|
| 2001 |
Maity A, Sall W, Koch CJ, Oprysko PR, Evans SM. Low pO2 and β-estradiol induce VEGF in MCF-7 and MCF-7-5C cells: Relationship to in vivo hypoxia Breast Cancer Research and Treatment. 67: 51-60. PMID 11518466 DOI: 10.1023/A:1010662905549 |
0.377 |
|
| 2001 |
Evans SM, Hahn SM, Magarelli DP, Zhang PJ, Jenkins WT, Fraker DL, Hsi RA, McKenna WG, Koch CJ. Hypoxia in human intraperitoneal and extremity sarcomas International Journal of Radiation Oncology Biology Physics. 49: 587-596. PMID 11173159 DOI: 10.1016/S0360-3016(00)01494-2 |
0.374 |
|
| 2001 |
Evans SM, Magarelli DP, Hahn SE, Koch CJ. Hypoxia and cellular proliferation in human tumors International Journal of Radiation Oncology Biology Physics. 51: 79-80. DOI: 10.1016/S0360-3016(01)01970-8 |
0.355 |
|
| 2000 |
Kajino H, Chen YQ, Chemtob S, Waleh N, Koch CJ, Clyman RI. Tissue hypoxia inhibits prostaglandin and nitric oxide production and prevents ductus arteriosus reopening American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 279. PMID 10896892 DOI: 10.1152/Ajpregu.2000.279.1.R278 |
0.346 |
|
| 2000 |
Ayene IS, Bernhard EJ, McKenna WG, Muschel RJ, Krisch RE, Koch CJ. DNA as an important target in radiation-induced apoptosis of MYC and MYC plus RAS transfected rat embryo fibroblasts International Journal of Radiation Biology. 76: 343-354. PMID 10757314 DOI: 10.1080/095530000138682 |
0.35 |
|
| 2000 |
Lee J, Moran JP, Fenton BM, Koch CJ, Frelinger JG, Keng PC, Lord EM. Alteration of tumour response to radiation by interleukin-2 gene transfer British Journal of Cancer. 82: 937-944. PMID 10732769 DOI: 10.1054/Bjoc.1999.1022 |
0.308 |
|
| 2000 |
Jenkins WT, Evans SM, Koch CJ. Hypoxia and necrosis in rat 9L glioma and Morris 7777 hepatoma tumors: Comparative measurements using EF5 binding and the Eppendorf needle electrode International Journal of Radiation Oncology Biology Physics. 46: 1005-1017. PMID 10705024 DOI: 10.1016/S0360-3016(99)00342-9 |
0.353 |
|
| 2000 |
Lew RJ, Evans SM, Kochman ML, Laughlin KM, Koch CJ. Elevated thiol levels in esophageal tumors: Cause of radiation and chemotherapy resistance? Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)81469-9 |
0.328 |
|
| 1999 |
Kavanagh MC, Tsang V, Chow S, Koch C, Hedley D, Minkin S, Hill RP. A comparison in individual murine tumors of techniques for measuring oxygen levels. International Journal of Radiation Oncology, Biology, Physics. 44: 1137-46. PMID 10421548 DOI: 10.1016/S0360-3016(99)00104-2 |
0.349 |
|
| 1999 |
Horan AD, Giandomenico AR, Koch CJ. Effect of oxygen on radiation-induced DNA damage in isolated nuclei Radiation Research. 152: 144-153. PMID 10409323 DOI: 10.2307/3580087 |
0.34 |
|
| 1999 |
Bergeron M, Evans SM, Sharp FR, Koch CJ, Lord EM, Ferriero DM. Detection of hypoxic cells with the 2-nitroimidazole, EF5, correlates with early redox changes in rat brain after perinatal hypoxia-ischemia. Neuroscience. 89: 1357-66. PMID 10362320 DOI: 10.1016/S0306-4522(98)00377-7 |
0.342 |
|
| 1999 |
Fenton BM, Paoni SF, Lee J, Koch CJ, Lord EM. Quantification of tumour vasculature and hypoxia by immunohistochemical staining and HbO2 saturation measurements. British Journal of Cancer. 79: 464-471. PMID 10027314 DOI: 10.1038/Sj.Bjc.6690072 |
0.34 |
|
| 1999 |
Clyman RI, Chan CY, Mauray F, Chen YQ, Cox W, Seidner SR, Lord EM, Weiss H, Waleh N, Evans SM, Koch CJ. Permanent anatomic closure of the ductus arteriosus in newborn baboons: The roles of postnatal constriction, hypoxia, and gestation Pediatric Research. 45: 19-29. PMID 9890604 DOI: 10.1203/00006450-199901000-00005 |
0.329 |
|
| 1998 |
Fenton BM, Paoni SF, Koch CJ, Lord EM. Effect of local irradiation on tumor oxygenation, perfused vessel density, and development of hypoxia Advances in Experimental Medicine and Biology. 454: 619-628. PMID 9889942 DOI: 10.1007/978-1-4615-4863-8_73 |
0.413 |
|
| 1998 |
Koch CJ, Chasan JE, Timothy Jenkins W, Chan CY, Laughlin KM, Evans SM. Co-localization of hypoxia and apoptosis in irradiated and untreated HCT116 human colon carcinoma xenografts Advances in Experimental Medicine and Biology. 454: 611-618. PMID 9889941 DOI: 10.1007/978-1-4615-4863-8_72 |
0.366 |
|
| 1998 |
Wilson DF, Laughlin KM, Rozanov C, Mokashi A, Vinogradov SA, Lahiri S, Koch CJ, Evans SM. Tissue oxygen sensing and the carotid body. Advances in Experimental Medicine and Biology. 454: 447-54. PMID 9889923 DOI: 10.1007/978-1-4615-4863-8_54 |
0.331 |
|
| 1998 |
Biaglow JE, Koch CJ, Tuttle SW, Manevich Y, Ayene IS, Bernhard EJ, McKenna WG, Kachur AV. The measurement of bioreductive capacity of tumor cells using methylene blue International Journal of Radiation Oncology Biology Physics. 42: 769-773. PMID 9845093 DOI: 10.1016/S0360-3016(98)00313-7 |
0.336 |
|
| 1998 |
Hicks KO, Fleming Y, Siim BG, Koch CJ, Wilson WR. Extravascular diffusion of tirapazamine: Effect of metabolic consumption assessed using the multicellular layer model International Journal of Radiation Oncology Biology Physics. 42: 641-649. PMID 9806526 DOI: 10.1016/S0360-3016(98)00268-5 |
0.325 |
|
| 1998 |
Carmeliet P, Dor Y, Herbert JM, Fukumura D, Brusselmans K, Dewerchin M, Neeman M, Bono F, Abramovitch R, Maxwell P, Koch CJ, Ratcliffe P, Moons L, Jain RK, Collen D, et al. Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature. 394: 485-90. PMID 9697772 DOI: 10.1038/28867 |
0.316 |
|
| 1998 |
Carmeliet P, Dor Y, Herbert J, Fukumura D, Brusselmans K, Dewerchin M, Neeman M, Bono F, Abramovitch R, Maxwell P, Koch CJ, Ratcliffe P, Moons L, Jain RK, Collen D, et al. Erratum: Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis Nature. 395: 525-525. DOI: 10.1038/26791 |
0.311 |
|
| 1997 |
Lo LW, Vinogradov SA, Koch CJ, Wilson DF. A new, water soluble, phosphor for oxygen measurements in vivo. Advances in Experimental Medicine and Biology. 428: 651-6. PMID 9500111 DOI: 10.1007/978-1-4615-5399-1_91 |
0.319 |
|
| 1997 |
Koch CJ, Lord EM, Shapiro IM, Clyman RI, Evans SM. Imaging hypoxia and blood flow in normal tissues Advances in Experimental Medicine and Biology. 428: 585-593. PMID 9500103 DOI: 10.1007/978-1-4615-5399-1_83 |
0.352 |
|
| 1997 |
Insug O, Datar S, Koch CJ, Shapiro IM, Shenker BJ. Mercuric compounds inhibit human monocyte function by inducing apoptosis: Evidence for formation of reactive oxygen species, development of mitochondrial membrane permeability transition and loss of reductive reserve Toxicology. 124: 211-224. PMID 9482123 DOI: 10.1016/S0300-483X(97)00153-4 |
0.338 |
|
| 1997 |
Horan AD, Chan CY, Pletcher CH, Menon C, Evans SM, Moore JS, Koch CJ. Analysis of tumor thiol concentrations: Comparison of flow cytometric with chemical and biochemical techniques Cytometry. 29: 76-82. PMID 9298814 DOI: 10.1002/(Sici)1097-0320(19970901)29:1<76::Aid-Cyto8>3.0.Co;2-B |
0.374 |
|
| 1997 |
Nozue M, Lee I, Yuan F, Teicher BA, Brizel DM, Dewhirst MW, Milross CC, Milas L, Song CW, Thomas CD, Guichard M, Evans SM, Koch CJ, Lord EM, Jain RK, et al. Interlaboratory variation in oxygen tension measurement by Eppendorf 'Histograph' and comparison with hypoxic marker Journal of Surgical Oncology. 66: 30-38. PMID 9290690 DOI: 10.1002/(Sici)1096-9098(199709)66:1<30::Aid-Jso7>3.0.Co;2-O |
0.366 |
|
| 1997 |
Evans SM, Jenkins WT, Shapiro M, Koch CJ. Evaluation of the concept of 'hypoxic fraction' as a descriptor of tumor oxygenation status Advances in Experimental Medicine and Biology. 411: 215-225. PMID 9269430 DOI: 10.1007/978-1-4615-5865-1_26 |
0.441 |
|
| 1997 |
Clyman RI, Evans S, Koch C. Hypoxia initiates Ductus Arteriosus Remodeling. • 101 Pediatric Research. 41: 19-19. DOI: 10.1203/00006450-199704001-00122 |
0.313 |
|
| 1996 |
Woods ML, Koch CJ, Lord EM. Detection of individual hypoxic cells in multicellular spheroids by flow cytometry using the 2-nitroimidazole, EF5, and monoclonal antibodies International Journal of Radiation Oncology Biology Physics. 34: 93-101. PMID 12118570 DOI: 10.1016/0360-3016(95)02006-3 |
0.398 |
|
| 1996 |
Ayene IS, Koch CJ, Krisch RE. Simulation of the cellular oxygen effect with an SV40 DNA model system using DNA strand breaks as an end point Radiation Research. 146: 501-509. PMID 8896576 DOI: 10.2307/3579550 |
0.386 |
|
| 1996 |
Marples B, Adomat H, Koch CJ, Skov KA. Response of V79 cells to low doses of X-rays and negative π-mesons: Clonogenic survival and DNA strand breaks International Journal of Radiation Biology. 70: 429-436. PMID 8862454 DOI: 10.1080/095530096144905 |
0.309 |
|
| 1996 |
Vinogradov SA, Lo LW, Jenkins WT, Evans SM, Koch C, Wilson DF. Noninvasive imaging of the distribution in oxygen in tissue in vivo using near-infrared phosphors Biophysical Journal. 70: 1609-1617. PMID 8785320 DOI: 10.1016/S0006-3495(96)79764-3 |
0.351 |
|
| 1996 |
Koch CJ, Evans SM. Cysteine concentrations in rodent tumors: Unexpectedly high values may cause therapy resistance International Journal of Cancer. 67: 661-667. PMID 8782655 DOI: 10.1002/(Sici)1097-0215(19960904)67:5<661::Aid-Ijc12>3.0.Co;2-8 |
0.432 |
|
| 1996 |
Rajpurohit R, Koch CJ, Tao Z, Teixeira CM, Shapiro IM. Adaptation of chondrocytes to low oxygen tension: relationship between hypoxia and cellular metabolism. Journal of Cellular Physiology. 168: 424-32. PMID 8707878 DOI: 10.1002/(Sici)1097-4652(199608)168:2<424::Aid-Jcp21>3.0.Co;2-1 |
0.388 |
|
| 1996 |
Lee J, Siemann DW, Koch CJ, Lord EM. Direct relationship between radiobiological hypoxia in tumors and monoclonal antibody detection of EF5 cellular adducts International Journal of Cancer. 67: 372-378. PMID 8707411 DOI: 10.1002/(Sici)1097-0215(19960729)67:3<372::Aid-Ijc11>3.0.Co;2-A |
0.428 |
|
| 1996 |
Lo LW, Koch CJ, Wilson DF. Calibration of oxygen-dependent quenching of the phosphorescence of Pd-meso-tetra (4-carboxyphenyl) porphine: A phosphor with general application for measuring oxygen concentration in biological systems Analytical Biochemistry. 236: 153-160. PMID 8619481 DOI: 10.1006/Abio.1996.0144 |
0.308 |
|
| 1996 |
Graeber TG, Osmanian C, Jacks T, Housman DE, Koch CJ, Lowe SW, Giaccia AJ. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature. 379: 88-91. PMID 8538748 DOI: 10.1038/379088A0 |
0.329 |
|
| 1995 |
Zhang H, Koch CJ, Wallen CA, Wheeler KT. Radiation-induced DNA damage in tumors and normal tissues. III. Oxygen dependence of the formation of strand breaks and DNA-protein crosslinks Radiation Research. 142: 163-168. PMID 7724730 |
0.304 |
|
| 1995 |
Ayene IS, Koch CJ, Krisch RE. Role of scavenger-derived radicals in the induction of double-strand and single-strand breaks in irradiated DNA Radiation Research. 142: 133-143. PMID 7724727 DOI: 10.2307/3579021 |
0.345 |
|
| 1995 |
Ayene IS, Koch CJ, Krisch RE. Modification of radiation-induced strand breaks by glutathione: Comparison of single- and double-strand breaks in SV40 DNA Radiation Research. 144: 1-8. PMID 7568762 DOI: 10.2307/3579229 |
0.362 |
|
| 1995 |
Evans SM, Joiner B, Jenkins WT, Laughlin KM, Lord EM, Koch CJ. Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2, 2, 3, 3, 3-pentafluoropropyl) acetamide] British Journal of Cancer. 72: 875-882. PMID 7547234 DOI: 10.1038/Bjc.1995.427 |
0.352 |
|
| 1995 |
Koch CJ, Evans SM, Lord EM. Oxygen dependence of cellular uptake of EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2, 2, 3, 3, 3-pentafluoropropyl)a cet amide]: Analysis of drug adducts by fluorescent antibodies vs bound radioactivity British Journal of Cancer. 72: 869-874. PMID 7547233 DOI: 10.1038/Bjc.1995.426 |
0.351 |
|
| 1995 |
Steven Wan X, Koch CJ, Lord EM, Manzone H, Billings PC, Donahue JJ, Odell CS, Miller JH, Schmidt NA, Kennedy AR. Monoclonal antibodies differentially reactive with native and reductively modified Bowman-Birk protease inhibitor Journal of Immunological Methods. 180: 117-130. PMID 7534802 DOI: 10.1016/0022-1759(94)00308-J |
0.3 |
|
| 1994 |
Tuttle SW, Hazard L, Koch CJ, Mitchell JB, Coleman CN, Biaglow JE. Bioreductive metabolism of SR-4233 (win 59075) by whole cell suspensions under aerobic and hypoxic conditions: Role of the pentose cycle and implications for the mechanism of cytotoxicity observed in air International Journal of Radiation Oncology, Biology, Physics. 29: 357-362. PMID 8195033 DOI: 10.1016/0360-3016(94)90289-5 |
0.318 |
|
| 1994 |
Koch CJ, Skov KA. Enhanced radiation-sensitivity by preincubation with nitroimidazoles: Effect of glutathione depletion International Journal of Radiation Oncology, Biology, Physics. 29: 345-349. PMID 8195031 DOI: 10.1016/0360-3016(94)90287-9 |
0.347 |
|
| 1994 |
Koch CJ, Giandomenico AR. Do low doses of radiation induce a response modulating induction or repair of DNA single-strand breaks? Radiation Research. 138. PMID 8146336 DOI: 10.2307/3578770 |
0.303 |
|
| 1994 |
Koch CJ, Giandomenico AR. The alkaline elution technique for measuring DNA single strand breaks: Increased reliability and sensitivity Analytical Biochemistry. 220: 58-65. PMID 7978258 DOI: 10.1006/Abio.1994.1299 |
0.304 |
|
| 1994 |
Skov KA, Koch CJ, Marples B. Effect of etanidazole on absolute sensitivity and increased radioresistance in hypoxic cells at low doses Radiation Oncology Investigations. 2: 164-170. DOI: 10.1002/Roi.2970020403 |
0.341 |
|
| 1994 |
Evans SM, Koch CJ. Radiation response and other characteristics of the 9l rat glioma grown as an epigastric tissue isolate Radiation Oncology Investigations. 2: 134-143. DOI: 10.1002/Roi.2970020305 |
0.352 |
|
| 1993 |
Koch CJ, Giandomenico AR, Chung Wha Lee Iyengar. Bioreductive metabolism of AF-2 [2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide] combined with 2-nitroimidazoles. Implications for use as hypoxic cell markers Biochemical Pharmacology. 46: 1029-1036. PMID 8216345 DOI: 10.1016/0006-2952(93)90667-L |
0.314 |
|
| 1992 |
Born JL, Smith BR, Harper N, Koch CJ. Metabolism and radiosensitization of 4,5-dimethylmisonidazole, a ring-substituted analog of misonidazole Biochemical Pharmacology. 43: 1337-1344. PMID 1562284 DOI: 10.1016/0006-2952(92)90511-G |
0.335 |
|
| 1992 |
Bump EA, Cerce BA, Al-Sarraf R, Pierce SM, Koch CJ. Radioprotection of DNA in isolated nuclei by naturally occurring thiols at intermediate oxygen tension Radiation Research. 132: 94-104. PMID 1410281 DOI: 10.2307/3578339 |
0.357 |
|
| 1992 |
Koch CJ, Skov KA. Comparisons of cellular radiation response using absolute rather than relative parameters Radiation Research. 132: 40-49. PMID 1410272 DOI: 10.2307/3578331 |
0.305 |
|
| 1989 |
Koch CJ, Stobbe CC, Hettiaratchi P. Combined radiation-protective and radiation-sensitizing agents IV: Measurement of intracellular protector concentrations International Journal of Radiation Oncology, Biology, Physics. 16: 1025-1027. PMID 2703380 DOI: 10.1016/0360-3016(89)90908-5 |
0.33 |
|
| 1988 |
Fuciarelli AF, Koch CJ, Raleigh JA. Oxygen dependence of product formation in irradiated adenosine 5'-monophosphate Radiation Research. 113: 447-457. PMID 3347702 DOI: 10.2307/3577242 |
0.333 |
|
| 1987 |
Franko AJ, Koch CJ, Garrecht BM, Sharplin J, Hughes D. Oxygen dependence of binding of misonidazole to rodent and human tumors in vitro Cancer Research. 47: 5367-5376. PMID 3652041 |
0.302 |
|
| 1987 |
Lepock JR, Cheng KH, Al-qysi H, Sim I, Koch CJ, Kruuv J. Hyperthermia-induced inhibition of respiration and mitochondrial protein denaturation in CHL cells International Journal of Hyperthermia. 3: 123-132. PMID 3036971 DOI: 10.3109/02656738709140380 |
0.59 |
|
| 1986 |
Urtasun RC, Koch CJ, Franko AJ, Raleigh JA, Chapman JD. A novel technique for measuring human tissue PO2 at the cellular level British Journal of Cancer. 54: 453-457. PMID 3756081 DOI: 10.1038/Bjc.1986.197 |
0.333 |
|
| 1984 |
Koch CJ, Stobbe CC, Bump EA. The Effect on the K m for Radiosensitization at 0°C of Thiol Depletion by Diethylmaleate Pretreatment: Quantitative Differences Found Using the Radiation Sensitizing Agent Misonidazole or Oxygen Radiation Research. 98: 141-153. DOI: 10.2307/3576058 |
0.388 |
|
| 1981 |
Koch CJ, Howell RL. Combined radiation-protective and radiation-sensitizing agents: II. Radiosensitivity of hypoxic or aerobic Chinese hamster fibroblasts in the presence of cysteamine and misonidazole: implications for the "oxygen effect" (with appendix on calculation of dose-modifying factors). Radiation Research. 87: 265. DOI: 10.2307/3575583 |
0.391 |
|
| 1980 |
Howell RL, Koch CJ. The disaggregation, separation and identification of cells from irradiated and unirradiated EMT6 mouse tumors. International Journal of Radiation Oncology Biology Physics. 6: 311-318. PMID 7390904 DOI: 10.1016/0360-3016(80)90139-X |
0.403 |
|
| 1979 |
Koch CJ, Howell RL, Biaglow JE. Ascorbate anion potentiates cytotoxicity of nitro-aromatic compounds under hypoxic and anoxic conditions. British Journal of Cancer. 39: 321-329. PMID 465301 DOI: 10.1038/Bjc.1979.56 |
0.319 |
|
| 1977 |
Harris JW, Koch CJ, Power JA, Biaglow JE. Radiosensitization of hypoxic mammalian cells by diamide. II. Studies of mechanism. Radiation Research. 70: 585. DOI: 10.2307/3574648 |
0.35 |
|
| 1977 |
Koch CJ, Meneses JJ, Harris JW. The effect of extreme hypoxia and glucose on the repair of potentially lethal and sublethal radiation damage by mammalian cells. Radiation Research. 70: 542-551. DOI: 10.2307/3574644 |
0.326 |
|
| 1975 |
Koch CJ, Painter RB. The effect of extreme hypoxia on the repair of DNA single-strand breaks in mammalian cells. Radiation Research. 64: 256-269. DOI: 10.2307/3574263 |
0.329 |
|
| 1973 |
Koch CJ, Kruuv J, Frey HE, Snyder RA. Plateau phase in growth induced by hypoxia. International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine. 23: 67-74. PMID 4539633 DOI: 10.1080/09553007314550061 |
0.619 |
|
| 1971 |
Nelson RJ, Kruuv J, Koch CJ, Frey HE. Effect of sub-optimal temperatures on survival of mammalian cells Experimental Cell Research. 68: 247-252. PMID 5166364 DOI: 10.1016/0014-4827(71)90148-0 |
0.586 |
|
| 1971 |
Koch CJ, Kruuv J. The effect of extreme hypoxia on recovery after radiation by synchronized mammalian cells. Radiation Research. 48: 74-85. DOI: 10.2307/3573396 |
0.367 |
|
| Show low-probability matches. |
