Year |
Citation |
Score |
2012 |
Fujimoto J, Kadara H, Garcia MM, Kabbout M, Behrens C, Liu DD, Lee JJ, Solis LM, Kim ES, Kalhor N, Moran C, Sharafkhaneh A, Lotan R, Wistuba II. G-protein coupled receptor family C, group 5, member A (GPRC5A) expression is decreased in the adjacent field and normal bronchial epithelia of patients with chronic obstructive pulmonary disease and non-small-cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 7: 1747-54. PMID 23154545 DOI: 10.1097/Jto.0B013E31826Bb1Ff |
0.632 |
|
2012 |
Hildebrandt MA, Lippman SM, Etzel CJ, Kim E, Lee JJ, Khuri FR, Spitz MR, Lotan R, Hong WK, Wu X. Genetic variants in the PI3K/PTEN/AKT/mTOR pathway predict head and neck cancer patient second primary tumor/recurrence risk and response to retinoid chemoprevention. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3705-13. PMID 22577058 DOI: 10.1158/1078-0432.Ccr-11-3271 |
0.354 |
|
2012 |
Barta P, Van Pelt C, Men T, Dickey BF, Lotan R, Moghaddam SJ. Enhancement of lung tumorigenesis in a Gprc5a Knockout mouse by chronic extrinsic airway inflammation. Molecular Cancer. 11: 4. PMID 22239913 DOI: 10.1186/1476-4598-11-4 |
0.331 |
|
2012 |
Oridate N, Lotan D, Mitchell M, Hong W, Lotan R. Induction of apoptosis by retinoids in human cervical-carcinoma cell-lines. International Journal of Oncology. 7: 433-41. PMID 21552857 DOI: 10.3892/ijo.7.3.433 |
0.313 |
|
2011 |
Gold KA, Lee JJ, Ping Y, Behrens C, Liu D, Lee H, Koo JS, Lotan R, Solis L, Rinsurongkawong W, Stewart DJ, Hofstetter WL, Swisher S, Lippman SM, Wistuba II, et al. Biologic risk model for recurrence in resected early-stage non-small cell lung cancer (ES NSCLC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 7053. PMID 28020037 DOI: 10.1200/Jco.2011.29.15_Suppl.7053 |
0.307 |
|
2011 |
Moussalli MJ, Wu Y, Zuo X, Yang XL, Wistuba II, Raso MG, Morris JS, Bowser JL, Minna JD, Lotan R, Shureiqi I. Mechanistic contribution of ubiquitous 15-lipoxygenase-1 expression loss in cancer cells to terminal cell differentiation evasion. Cancer Prevention Research (Philadelphia, Pa.). 4: 1961-72. PMID 21881028 DOI: 10.1158/1940-6207.Capr-10-0280 |
0.479 |
|
2011 |
Zhao M, Sano D, Pickering CR, Jasser SA, Henderson YC, Clayman GL, Sturgis EM, Ow TJ, Lotan R, Carey TE, Sacks PG, Grandis JR, Sidransky D, Heldin NE, Myers JN. Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 7248-64. PMID 21868764 DOI: 10.1158/1078-0432.Ccr-11-0690 |
0.388 |
|
2011 |
Kadara H, Behrens C, Yuan P, Solis L, Liu D, Gu X, Minna JD, Lee JJ, Kim E, Hong WK, Wistuba II, Lotan R. A five-gene and corresponding protein signature for stage-I lung adenocarcinoma prognosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 1490-501. PMID 21163870 DOI: 10.1158/1078-0432.Ccr-10-2703 |
0.625 |
|
2011 |
Kadara H, Lotan R. Effects of natural and synthetic retinoids on the differentiation and growth of squamous cancers Signaling Pathways in Squamous Cancer. 261-282. DOI: 10.1007/978-1-4419-7203-3_13 |
0.625 |
|
2010 |
Chen Y, Deng J, Fujimoto J, Kadara H, Men T, Lotan D, Lotan R. Gprc5a deletion enhances the transformed phenotype in normal and malignant lung epithelial cells by eliciting persistent Stat3 signaling induced by autocrine leukemia inhibitory factor. Cancer Research. 70: 8917-26. PMID 20959490 DOI: 10.1158/0008-5472.Can-10-0518 |
0.67 |
|
2010 |
Fujimoto J, Kadara H, Men T, van Pelt C, Lotan D, Lotan R. Comparative functional genomics analysis of NNK tobacco-carcinogen induced lung adenocarcinoma development in Gprc5a-knockout mice. Plos One. 5: e11847. PMID 20686609 DOI: 10.1371/Journal.Pone.0011847 |
0.602 |
|
2010 |
Fujimoto J, Kong M, Lee JJ, Hong WK, Lotan R. Validation of a novel statistical model for assessing the synergy of combined-agent cancer chemoprevention. Cancer Prevention Research (Philadelphia, Pa.). 3: 917-28. PMID 20663979 DOI: 10.1158/1940-6207.Capr-10-0129 |
0.41 |
|
2010 |
Wang J, Lippman SM, Lee JJ, Yang H, Khuri FR, Kim E, Lin J, Chang DW, Lotan R, Hong WK, Wu X. Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma. Carcinogenesis. 31: 1755-61. PMID 20627871 DOI: 10.1093/Carcin/Bgq138 |
0.312 |
|
2010 |
Kadara H, Fujimoto J, Men T, Ye X, Lotan D, Lee JS, Lotan R. A Gprc5a tumor suppressor loss of expression signature is conserved, prevalent, and associated with survival in human lung adenocarcinomas. Neoplasia (New York, N.Y.). 12: 499-505. PMID 20563252 DOI: 10.1593/Neo.10390 |
0.644 |
|
2010 |
Lee JJ, Feng L, Reshef DS, Sabichi AL, Williams B, Rinsurongkawong W, Wistuba II, Lotan R, Lippman SM. Mortality in the randomized, controlled lung intergroup trial of isotretinoin. Cancer Prevention Research (Philadelphia, Pa.). 3: 738-44. PMID 20501862 DOI: 10.1158/1940-6207.Capr-09-0124 |
0.326 |
|
2010 |
Deng J, Fujimoto J, Ye XF, Men TY, Van Pelt CS, Chen YL, Lin XF, Kadara H, Tao Q, Lotan D, Lotan R. Knockout of the tumor suppressor gene Gprc5a in mice leads to NF-kappaB activation in airway epithelium and promotes lung inflammation and tumorigenesis. Cancer Prevention Research (Philadelphia, Pa.). 3: 424-37. PMID 20354164 DOI: 10.1158/1940-6207.Capr-10-0032 |
0.627 |
|
2010 |
Chakravarti N, Kadara H, Yoon DJ, Shay JW, Myers JN, Lotan D, Sonenberg N, Lotan R. Differential inhibition of protein translation machinery by curcumin in normal, immortalized, and malignant oral epithelial cells. Cancer Prevention Research (Philadelphia, Pa.). 3: 331-8. PMID 20145189 DOI: 10.1158/1940-6207.Capr-09-0076 |
0.648 |
|
2010 |
Kim ES, Hong WK, Lee JJ, Mao L, Morice RC, Liu DD, Jimenez CA, Eapen GA, Lotan R, Tang X, Newman RA, Wistuba II, Kurie JM. Biological activity of celecoxib in the bronchial epithelium of current and former smokers. Cancer Prevention Research (Philadelphia, Pa.). 3: 148-59. PMID 20103722 DOI: 10.1158/1940-6207.Capr-09-0233 |
0.317 |
|
2010 |
Behrens C, Feng L, Kadara H, Kim HJ, Lee JJ, Mehran R, Hong WK, Lotan R, Wistuba II. Expression of interleukin-1 receptor-associated kinase-1 in non-small cell lung carcinoma and preneoplastic lesions. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 34-44. PMID 20028769 DOI: 10.1158/1078-0432.Ccr-09-0650 |
0.622 |
|
2010 |
Kim SJ, Choi IJ, Cheong TC, Lee SJ, Lotan R, Park SH, Chun KH. Galectin-3 increases gastric cancer cell motility by up-regulating fascin-1 expression. Gastroenterology. 138: 1035-45.e1-2. PMID 19818782 DOI: 10.1053/J.Gastro.2009.09.061 |
0.388 |
|
2010 |
Zhang X, Yang H, Lee JJ, Kim E, Lippman SM, Khuri FR, Spitz MR, Lotan R, Hong WK, Wu X. Abstract PR-03: Genetic variations in microRNA biogenesis genes as predictors for risk of second primary tumor (SPT) and/or recurrence in patients with early‐stage head and neck cancer Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-Pr-03 |
0.302 |
|
2010 |
Lotan R. Abstract PL02-03: Insights from a new mouse model into the role of inflammation at early stages of lung carcinogenesis Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-Pl02-03 |
0.476 |
|
2010 |
Hildebrandt MAT, Lippman SM, Kim E, Lee JJ, Khuri F, Spitz MR, Lotan R, Hong WK, Wu X. Abstract B94: Pharmacogenetics of retinoid chemoprevention in head and neck cancer patients: Modulation of response by common genetic variation in the mTOR signaling pathway Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-B94 |
0.315 |
|
2010 |
Chen Y, Deng J, Fujimoto J, Kadara H, Ye X, Men T, Lotan D, Lotan R. Abstract 4995: Loss of the lung-specific tumor suppressor Gprc5a causes persistent activation of Stat3 leading to increased survival signaling in normal and malignant lung epithelial cells Cancer Research. 70: 4995-4995. DOI: 10.1158/1538-7445.Am10-4995 |
0.675 |
|
2010 |
Kadara HN, Hong WK, Wistuba II, Lotan R. Abstract 4817: A five-gene signature predictive of survival in lung adenocarcinoma but not in squamous cell carcinoma Cancer Research. 70: 4817-4817. DOI: 10.1158/1538-7445.Am10-4817 |
0.388 |
|
2010 |
Fujimoto J, Kadara HN, Tao Q, Men T, Pelt Cv, Lotan D, Lotan R. Abstract 2466: Tobacco carcinogen-enhanced lung tumorigenesis in Gprc5a knockout mice recapitulates human lung cancer development Cancer Research. 70: 2466-2466. DOI: 10.1158/1538-7445.Am10-2466 |
0.444 |
|
2009 |
Moghaddam SJ, Barta P, Mirabolfathinejad SG, Ammar-Aouchiche Z, Garza NT, Vo TT, Newman RA, Aggarwal BB, Evans CM, Tuvim MJ, Lotan R, Dickey BF. Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice. Carcinogenesis. 30: 1949-56. PMID 19793800 DOI: 10.1093/Carcin/Bgp229 |
0.422 |
|
2009 |
Kadara H, Lacroix L, Behrens C, Solis L, Gu X, Lee JJ, Tahara E, Lotan D, Hong WK, Wistuba II, Lotan R. Identification of gene signatures and molecular markers for human lung cancer prognosis using an in vitro lung carcinogenesis system. Cancer Prevention Research (Philadelphia, Pa.). 2: 702-11. PMID 19638491 DOI: 10.1158/1940-6207.Capr-09-0084 |
0.64 |
|
2009 |
Wu X, Spitz MR, Lee JJ, Lippman SM, Ye Y, Yang H, Khuri FR, Kim E, Gu J, Lotan R, Hong WK. Novel susceptibility loci for second primary tumors/recurrence in head and neck cancer patients: large-scale evaluation of genetic variants. Cancer Prevention Research (Philadelphia, Pa.). 2: 617-24. PMID 19584075 DOI: 10.1158/1940-6207.Capr-09-0025 |
0.312 |
|
2009 |
Brannan JM, Dong W, Prudkin L, Behrens C, Lotan R, Bekele BN, Wistuba I, Johnson FM. Expression of the receptor tyrosine kinase EphA2 is increased in smokers and predicts poor survival in non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 4423-30. PMID 19531623 DOI: 10.1158/1078-0432.Ccr-09-0473 |
0.428 |
|
2009 |
Tahara E, Kadara H, Lacroix L, Lotan D, Lotan R. Activation of protein kinase C by phorbol 12-myristate 13-acetate suppresses the growth of lung cancer cells through KLF6 induction. Cancer Biology & Therapy. 8: 801-7. PMID 19333010 DOI: 10.4161/Cbt.8.9.8186 |
0.682 |
|
2009 |
Ye X, Tao Q, Wang Y, Cheng Y, Lotan R. Mechanisms underlying the induction of the putative human tumor suppressor GPRC5A by retinoic acid. Cancer Biology & Therapy. 8: 951-62. PMID 19279407 DOI: 10.4161/Cbt.8.10.8244 |
0.375 |
|
2009 |
Song S, Guan B, Men T, Hoque A, Lotan R, Xu XC. Antitumor effect of retinoic acid receptor-beta2 associated with suppression of cyclooxygenase-2. Cancer Prevention Research (Philadelphia, Pa.). 2: 274-80. PMID 19258542 DOI: 10.1158/1940-6207.Capr-08-0180 |
0.383 |
|
2009 |
Hail N, Lotan R. Cancer chemoprevention and mitochondria: targeting apoptosis in transformed cells via the disruption of mitochondrial bioenergetics/redox state. Molecular Nutrition & Food Research. 53: 49-67. PMID 19051186 DOI: 10.1002/Mnfr.200700527 |
0.376 |
|
2008 |
Behrens C, Lin HY, Lee JJ, Raso MG, Hong WK, Wistuba II, Lotan R. Immunohistochemical expression of basic fibroblast growth factor and fibroblast growth factor receptors 1 and 2 in the pathogenesis of lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 6014-22. PMID 18829480 DOI: 10.1158/1078-0432.Ccr-08-0167 |
0.442 |
|
2008 |
Kadara H, Tahara E, Kim HJ, Lotan D, Myers J, Lotan R. Involvement of Rac in fenretinide-induced apoptosis. Cancer Research. 68: 4416-23. PMID 18519704 DOI: 10.1158/0008-5472.Can-08-0031 |
0.678 |
|
2008 |
Ye X, Lotan R. Potential misinterpretation of data on differential gene expression in normal and malignant cells in vitro. Briefings in Functional Genomics & Proteomics. 7: 322-6. PMID 18467351 DOI: 10.1093/bfgp/eln021 |
0.307 |
|
2007 |
Gillenwater AM, Zhong M, Lotan R. Histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis through both mitochondrial and Fas (Cd95) signaling in head and neck squamous carcinoma cells. Molecular Cancer Therapeutics. 6: 2967-75. PMID 18025281 DOI: 10.1158/1535-7163.Mct-04-0344 |
0.426 |
|
2007 |
Tao Q, Fujimoto J, Men T, Ye X, Deng J, Lacroix L, Clifford JL, Mao L, Van Pelt CS, Lee JJ, Lotan D, Lotan R. Identification of the retinoic acid-inducible Gprc5a as a new lung tumor suppressor gene. Journal of the National Cancer Institute. 99: 1668-82. PMID 18000218 DOI: 10.1093/Jnci/Djm208 |
0.443 |
|
2007 |
Chakravarti N, Lotan R, Diwan AH, Warneke CL, Johnson MM, Prieto VG. Decreased expression of retinoid receptors in melanoma: entailment in tumorigenesis and prognosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 4817-24. PMID 17699860 DOI: 10.1158/1078-0432.Ccr-06-3026 |
0.393 |
|
2007 |
Kim SW, Cheon K, Kim CH, Yoon JH, Hawke DH, Kobayashi R, Prudkin L, Wistuba II, Lotan R, Hong WK, Koo JS. Proteomics-based identification of proteins secreted in apical surface fluid of squamous metaplastic human tracheobronchial epithelial cells cultured by three-dimensional organotypic air-liquid interface method. Cancer Research. 67: 6565-73. PMID 17638865 DOI: 10.1158/0008-5472.Can-06-2783 |
0.44 |
|
2007 |
Schroeder CP, Yang P, Newman RA, Lotan R. Simultaneous inhibition of COX-2 and 5-LOX activities augments growth arrest and death of premalignant and malignant human lung cell lines. Journal of Experimental Therapeutics & Oncology. 6: 183-92. PMID 17552358 |
0.337 |
|
2007 |
Kadara H, Lacroix L, Lotan D, Lotan R. Induction of endoplasmic reticulum stress by the pro-apoptotic retinoid N-(4-hydroxyphenyl)retinamide via a reactive oxygen species-dependent mechanism in human head and neck cancer cells. Cancer Biology & Therapy. 6: 705-11. PMID 17404501 DOI: 10.4161/Cbt.6.5.3963 |
0.598 |
|
2006 |
Williams MD, Chakravarti N, Kies MS, Maruya S, Myers JN, Haviland JC, Weber RS, Lotan R, El-Naggar AK. Implications of methylation patterns of cancer genes in salivary gland tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 7353-8. PMID 17189407 DOI: 10.1158/1078-0432.Ccr-06-1272 |
0.325 |
|
2006 |
Shen J, Behrens C, Wistuba II, Feng L, Lee JJ, Hong WK, Lotan R. Identification and validation of differences in protein levels in normal, premalignant, and malignant lung cells and tissues using high-throughput Western Array and immunohistochemistry. Cancer Research. 66: 11194-206. PMID 17145864 DOI: 10.1158/0008-5472.Can-04-1444 |
0.48 |
|
2006 |
Germain P, Chambon P, Eichele G, Evans RM, Lazar MA, Leid M, De Lera AR, Lotan R, Mangelsdorf DJ, Gronemeyer H. International Union of Pharmacology. LXIII. Retinoid X receptors. Pharmacological Reviews. 58: 760-72. PMID 17132853 DOI: 10.1124/Pr.58.4.7 |
0.302 |
|
2006 |
Germain P, Chambon P, Eichele G, Evans RM, Lazar MA, Leid M, De Lera AR, Lotan R, Mangelsdorf DJ, Gronemeyer H. International Union of Pharmacology. LX. Retinoic acid receptors. Pharmacological Reviews. 58: 712-25. PMID 17132850 DOI: 10.1124/Pr.58.4.4 |
0.332 |
|
2006 |
Schroeder CP, Kadara H, Lotan D, Woo JK, Lee HY, Hong WK, Lotan R. Involvement of mitochondrial and Akt signaling pathways in augmented apoptosis induced by a combination of low doses of celecoxib and N-(4-hydroxyphenyl) retinamide in premalignant human bronchial epithelial cells. Cancer Research. 66: 9762-70. PMID 17018636 DOI: 10.1158/0008-5472.Can-05-4124 |
0.635 |
|
2006 |
Liang ZD, Lippman SM, Wu TT, Lotan R, Xu XC. RRIG1 mediates effects of retinoic acid receptor beta2 on tumor cell growth and gene expression through binding to and inhibition of RhoA. Cancer Research. 66: 7111-8. PMID 16849557 DOI: 10.1158/0008-5472.Can-06-0812 |
0.441 |
|
2006 |
Lacroix L, Feng G, Lotan R. Identification of genes expressed differentially in an in vitro human lung carcinogenesis model. Cancer Biology & Therapy. 5: 665-73. PMID 16775421 DOI: 10.4161/Cbt.5.6.2870 |
0.488 |
|
2006 |
Kadara H, Schroeder CP, Lotan D, Pisano C, Lotan R. Induction of GDF-15/NAG-1/MIC-1 in human lung carcinoma cells by retinoid-related molecules and assessment of its role in apoptosis. Cancer Biology & Therapy. 5: 518-22. PMID 16582595 DOI: 10.4161/Cbt.5.5.2602 |
0.624 |
|
2006 |
Fukumori T, Oka N, Takenaka Y, Nangia-Makker P, Elsamman E, Kasai T, Shono M, Kanayama HO, Ellerhorst J, Lotan R, Raz A. Galectin-3 regulates mitochondrial stability and antiapoptotic function in response to anticancer drug in prostate cancer. Cancer Research. 66: 3114-9. PMID 16540661 DOI: 10.1158/0008-5472.Can-05-3750 |
0.416 |
|
2006 |
Chakravarti N, El-Naggar AK, Lotan R, Anderson J, Diwan AH, Saadati HG, Diba R, Prieto VG, Esmaeli B. Expression of retinoid receptors in sebaceous cell carcinoma. Journal of Cutaneous Pathology. 33: 10-7. PMID 16441406 DOI: 10.1111/J.0303-6987.2006.00396.X |
0.346 |
|
2006 |
Kim HJ, Chakravarti N, Oridate N, Choe C, Claret FX, Lotan R. N-(4-hydroxyphenyl)retinamide-induced apoptosis triggered by reactive oxygen species is mediated by activation of MAPKs in head and neck squamous carcinoma cells Oncogene. 25: 2785-2794. PMID 16407847 DOI: 10.1038/Sj.Onc.1209303 |
0.342 |
|
2005 |
Zelent A, Petrie K, Lotan R, Waxman S, Gore SD. Clinical translation of epigenetics in cancer: eN-CORe--a report on the second workshop. Molecular Cancer Therapeutics. 4: 1810-9. PMID 16276003 DOI: 10.1158/1535-7163.Mct-05-0230 |
0.335 |
|
2005 |
Shishodia S, Gutierrez AM, Lotan R, Aggarwal BB. N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products. Cancer Research. 65: 9555-65. PMID 16230421 DOI: 10.1158/0008-5472.Can-05-1585 |
0.342 |
|
2005 |
Kim HJ, Oridate N, Lotan R. Increased level of the p67phox subunit of NADPH oxidase by 4HPR in head and neck squamous carcinoma cells. International Journal of Oncology. 27: 787-90. PMID 16077929 DOI: 10.3892/Ijo.27.3.787 |
0.454 |
|
2005 |
Chakravarti N, Saadati HG, El-Naggar AK, Lotan R, Diba RE, Esmaeli B. Retinoid receptor subtypes in sebaceous cell carcinoma of the eyelid. Ophthalmic Plastic and Reconstructive Surgery. 21: 292-7. PMID 16052143 DOI: 10.1097/01.Iop.0000172180.94824.79 |
0.372 |
|
2005 |
Ju Z, Kapoor M, Newton K, Cheon K, Ramaswamy A, Lotan R, Strong LC, Koo JS. Global detection of molecular changes reveals concurrent alteration of several biological pathways in nonsmall cell lung cancer cells Molecular Genetics and Genomics. 274: 141-154. PMID 16049682 DOI: 10.1007/S00438-005-0014-7 |
0.464 |
|
2005 |
Jin F, Liu X, Zhou Z, Yue P, Lotan R, Khuri FR, Chung LW, Sun SY. Activation of nuclear factor-kappaB contributes to induction of death receptors and apoptosis by the synthetic retinoid CD437 in DU145 human prostate cancer cells. Cancer Research. 65: 6354-63. PMID 16024638 DOI: 10.1158/0008-5472.Can-04-4061 |
0.354 |
|
2005 |
Lee HY, Chang YS, Han JY, Liu DD, Lee JJ, Lotan R, Spitz MR, Hong WK. Effects of 9-cis-retinoic acid on the insulin-like growth factor axis in former smokers. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 4439-49. PMID 15994153 DOI: 10.1200/Jco.2005.04.572 |
0.344 |
|
2005 |
Maruya SI, Myers JN, Weber RS, Rosenthal DI, Lotan R, El-Naggar AK. ICAM-5 (telencephalin) gene expression in head and neck squamous carcinoma tumorigenesis and perineural invasion! Oral Oncology. 41: 580-588. PMID 15975520 DOI: 10.1016/J.Oraloncology.2005.01.002 |
0.407 |
|
2005 |
Sun SY, Schroeder CP, Yue P, Lotan D, Hong WK, Lotan R. Enhanced growth inhibition and apoptosis induction in NSCLC cell lines by combination of celecoxib and 4HPR at clinically relevant concentrations. Cancer Biology & Therapy. 4: 407-13. PMID 15846100 DOI: 10.4161/Cbt.4.4.1618 |
0.454 |
|
2005 |
Oridate N, Kim HJ, Xu X, Lotan R. Growth inhibition of head and neck squamous carcinoma cells by small interfering RNAs targeting eIF4E or cyclin D1 alone or combined with cisplatin. Cancer Biology & Therapy. 4: 318-23. PMID 15846092 DOI: 10.4161/Cbt.4.3.1504 |
0.417 |
|
2005 |
Chun KH, Pfahl M, Lotan R. Induction of apoptosis by the synthetic retinoid MX3350-1 through extrinsic and intrinsic pathways in head and neck squamous carcinoma cells. Oncogene. 24: 3669-77. PMID 15782141 DOI: 10.1038/Sj.Onc.1208339 |
0.408 |
|
2005 |
Zelent A, Petrie K, Chen Z, Lotan R, Lübbert M, Tallman MS, Ohno R, Degos L, Waxman S. Molecular target-based treatment of human cancer: summary of the 10th international conference on differentiation therapy. Cancer Research. 65: 1117-23. PMID 15734991 DOI: 10.1158/0008-5472.Can-04-3603 |
0.301 |
|
2005 |
Oridate N, Lotan R. Suppression of DNA methyltransferase 1 levels in head and neck squamous carcinoma cells using small interfering RNA results in growth inhibition and increase in Cdk inhibitor p21. International Journal of Oncology. 26: 757-61. PMID 15703834 DOI: 10.3892/Ijo.26.3.757 |
0.443 |
|
2005 |
Kim HJ, Lotan R. Identification of protein modulation by the synthetic retinoid CD437 in lung carcinoma cells using high throughput immunoblotting. International Journal of Oncology. 26: 483-91. PMID 15645134 DOI: 10.3892/Ijo.26.2.483 |
0.414 |
|
2005 |
Lotan R. A crucial role for cellular retinol-binding protein I in retinoid signaling. Journal of the National Cancer Institute. 97: 3-4. PMID 15632368 DOI: 10.1093/Jnci/Dji031 |
0.354 |
|
2005 |
Zou C, Ramakumar S, Qian L, Zou C, Zang R, Wang J, Grossman HB, Lotan R, Liebert M. Effect of retinoic acid and interferon alpha-2a on transitional cell carcinoma of bladder. The Journal of Urology. 173: 247-51. PMID 15592090 DOI: 10.1097/01.Ju.0000141584.50650.26 |
0.408 |
|
2005 |
Meric-Bernstam F, Zhang H, Lotan R, Lotan D, Sahin A, Babiera GV, Kopelovich L, Crowell JA, Strong LC. Feasibility of the use of primary breast epithelial cell cultures to identify genotype-specific preventive agents Journal of Clinical Oncology. 23: 3140-3140. DOI: 10.1200/Jco.2005.23.16_Suppl.3140 |
0.316 |
|
2005 |
Lotan R, Men T, Fujimoto J, Tao Q. P-081 Gpcr5a-knockout mouse: A novel model for spontaneous and tobacco carcinogen-enhanced lung adenocarcinoma Lung Cancer. 49: S135. DOI: 10.1016/S0169-5002(05)80575-6 |
0.335 |
|
2004 |
Hsi LC, Xi X, Lotan R, Shureiqi I, Lippman SM. The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells. Cancer Research. 64: 8778-81. PMID 15574791 DOI: 10.1158/0008-5472.Can-04-1867 |
0.441 |
|
2004 |
Lu C, Soria JC, Tang X, Xu XC, Wang L, Mao L, Lotan R, Kemp B, Bekele BN, Feng L, Hong WK, Khuri FR. Prognostic factors in resected stage I non-small-cell lung cancer: a multivariate analysis of six molecular markers. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 4575-83. PMID 15542809 DOI: 10.1200/Jco.2004.01.091 |
0.419 |
|
2004 |
Lee HY, Moon H, Chun KH, Chang YS, Hassan K, Ji L, Lotan R, Khuri FR, Hong WK. Effects of insulin-like growth factor binding protein-3 and farnesyltransferase inhibitor SCH66336 on Akt expression and apoptosis in non-small-cell lung cancer cells. Journal of the National Cancer Institute. 96: 1536-48. PMID 15494604 DOI: 10.1093/Jnci/Djh286 |
0.474 |
|
2004 |
Zou W, Liu X, Yue P, Zhou Z, Sporn MB, Lotan R, Khuri FR, Sun SY. c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells. Cancer Research. 64: 7570-8. PMID 15492284 DOI: 10.1158/0008-5472.Can-04-1238 |
0.403 |
|
2004 |
Youssef EM, Issa JP, Lotan R. Regulation of RARbeta1 expression in head and neck cancer cells by cell density-dependent chromatin remodeling. Cancer Biology & Therapy. 3: 1002-6. PMID 15467435 DOI: 10.4161/Cbt.3.10.1139 |
0.418 |
|
2004 |
Choi JH, Chun KH, Raz A, Lotan R. Inhibition of N-(4-hydroxyphenyl)retinamide-induced apoptosis in breast cancer cells by galectin-3. Cancer Biology & Therapy. 3: 447-52. PMID 15326375 DOI: 10.4161/Cbt.3.5.808 |
0.44 |
|
2004 |
Khuri FR, Lotan R. Retinoids in lung cancer: friend, foe, or fellow traveler? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 3435-7. PMID 15277536 DOI: 10.1200/Jco.2004.05.947 |
0.388 |
|
2004 |
Schroeder CP, Yang P, Newman RA, Lotan R. Eicosanoid metabolism in squamous cell carcinoma cell lines derived from primary and metastatic head and neck cancer and its modulation by celecoxib. Cancer Biology & Therapy. 3: 847-52. PMID 15254428 DOI: 10.4161/Cbt.3.9.1037 |
0.432 |
|
2004 |
Lotan R, Lotan Y. Retinoic acid receptor beta2 hypermethylation: implications for prostate cancer detection, prevention, and therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 3935-6. PMID 15217922 DOI: 10.1158/1078-0432.Ccr-04-0536 |
0.392 |
|
2004 |
Maruya S, Issa JP, Weber RS, Rosenthal DI, Haviland JC, Lotan R, El-Naggar AK. Differential methylation status of tumor-associated genes in head and neck squamous carcinoma: incidence and potential implications. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 3825-30. PMID 15173091 DOI: 10.1158/1078-0432.Ccr-03-0370 |
0.316 |
|
2004 |
Sun SY, Hail N, Lotan R. Apoptosis as a novel target for cancer chemoprevention. Journal of the National Cancer Institute. 96: 662-72. PMID 15126603 DOI: 10.1093/Jnci/Djh123 |
0.436 |
|
2004 |
Kim HJ, Lotan R. Identification of retinoid-modulated proteins in squamous carcinoma cells using high-throughput immunoblotting. Cancer Research. 64: 2439-48. PMID 15059897 DOI: 10.1158/0008-5472.Can-03-2643 |
0.417 |
|
2004 |
Youssef EM, Chen XQ, Higuchi E, Kondo Y, Garcia-Manero G, Lotan R, Issa JP. Hypermethylation and silencing of the putative tumor suppressor Tazarotene-induced gene 1 in human cancers. Cancer Research. 64: 2411-7. PMID 15059893 DOI: 10.1158/0008-5472.Can-03-0164 |
0.446 |
|
2004 |
Youssef EM, Lotan D, Issa JP, Wakasa K, Fan YH, Mao L, Hassan K, Feng L, Lee JJ, Lippman SM, Hong WK, Lotan R. Hypermethylation of the retinoic acid receptor-beta(2) gene in head and neck carcinogenesis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 1733-42. PMID 15014026 DOI: 10.1158/1078-0432.Ccr-0989-3 |
0.333 |
|
2004 |
Yang Z, Bagheri-Yarmand R, Wang RA, Adam L, Papadimitrakopoulou VV, Clayman GL, El-Naggar A, Lotan R, Barnes CJ, Hong WK, Kumar R. The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (Iressa) suppresses c-Src and Pak1 pathways and invasiveness of human cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 658-67. PMID 14760089 DOI: 10.1158/1078-0432.Ccr-0382-03 |
0.419 |
|
2004 |
Hail N, Konopleva M, Sporn M, Lotan R, Andreeff M. Evidence supporting a role for calcium in apoptosis induction by the synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO). The Journal of Biological Chemistry. 279: 11179-87. PMID 14711815 DOI: 10.1074/Jbc.M312758200 |
0.39 |
|
2004 |
Tao Q, Cheng Y, Clifford J, Lotan R. Characterization of the murine orphan G-protein-coupled receptor gene Rai3 and its regulation by retinoic acid. Genomics. 83: 270-80. PMID 14706456 DOI: 10.1016/S0888-7543(03)00237-4 |
0.306 |
|
2004 |
Appierto V, Villani MG, Cavadini E, Lotan R, Vinson C, Formelli F. Involvement of c-Fos in fenretinide-induced apoptosis in human ovarian carcinoma cells Cell Death and Differentiation. 11: 270-279. PMID 14647238 DOI: 10.1038/sj.cdd.4401349 |
0.305 |
|
2003 |
Sudbø J, Bryne M, Mao L, Lotan R, Reith A, Kildal W, Davidson B, Søland TM, Lippman SM. Molecular based treatment of oral cancer. Oral Oncology. 39: 749-58. PMID 13679198 DOI: 10.1016/S1368-8375(03)00098-8 |
0.362 |
|
2003 |
Higuchi E, Chandraratna RA, Hong WK, Lotan R. Induction of TIG3, a putative class II tumor suppressor gene, by retinoic acid in head and neck and lung carcinoma cells and its association with suppression of the transformed phenotype. Oncogene. 22: 4627-35. PMID 12879006 DOI: 10.1038/Sj.Onc.1206235 |
0.499 |
|
2003 |
Chun KH, Benbrook DM, Berlin KD, Hong WK, Lotan R. The synthetic heteroarotinoid SHetA2 induces apoptosis in squamous carcinoma cells through a receptor-independent and mitochondria-dependent pathway. Cancer Research. 63: 3826-32. PMID 12839980 |
0.346 |
|
2003 |
Huh JJ, Wolf JK, Fightmaster DL, Lotan R, Follen M. Transduction of adenovirus-mediated wild-type p53 after radiotherapy in human cervical cancer cells. Gynecologic Oncology. 89: 243-50. PMID 12713987 DOI: 10.1016/S0090-8258(03)00054-4 |
0.353 |
|
2003 |
Chun KH, Kosmeder JW, Sun S, Pezzuto JM, Lotan R, Hong WK, Lee HY. Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells. Journal of the National Cancer Institute. 95: 291-302. PMID 12591985 DOI: 10.1093/Jnci/95.4.291 |
0.418 |
|
2003 |
Hayashi K, Goodison S, Urquidi V, Tarin D, Lotan R, Tahara E. Differential effects of retinoic acid on the growth of isogenic metastatic and non-metastatic breast cancer cell lines and their association with distinct expression of retinoic acid receptor beta isoforms 2 and 4. International Journal of Oncology. 22: 623-9. PMID 12579317 |
0.312 |
|
2003 |
Kurie JM, Lotan R, Lee JJ, Lee JS, Morice RC, Liu DD, Xu XC, Khuri FR, Ro JY, Hittelman WN, Walsh GL, Roth JA, Minna JD, Hong WK. Treatment of former smokers with 9-cis-retinoic acid reverses loss of retinoic acid receptor-beta expression in the bronchial epithelium: results from a randomized placebo-controlled trial. Journal of the National Cancer Institute. 95: 206-14. PMID 12569142 DOI: 10.1093/Jnci/95.3.206 |
0.316 |
|
2003 |
Faderl S, Lotan R, Kantarjian HM, Harris D, Van Q, Estrov Z. N-(4-Hydroxylphenyl)retinamide (fenretinide, 4-HPR), a retinoid compound with antileukemic and proapoptotic activity in acute lymphoblastic leukemia (ALL). Leukemia Research. 27: 259-66. PMID 12537979 DOI: 10.1016/S0145-2126(02)00162-5 |
0.381 |
|
2003 |
Soria JC, Xu X, Liu DD, Lee JJ, Kurie J, Morice RC, Khuri F, Mao L, Hong WK, Lotan R. Retinoic acid receptor beta and telomerase catalytic subunit expression in bronchial epithelium of heavy smokers. Journal of the National Cancer Institute. 95: 165-8. PMID 12529350 DOI: 10.1093/Jnci/95.2.165 |
0.343 |
|
2003 |
Lotan R, Feng G. P-268 Application of an in vitro cell model and cDNA array for the identification of genes expressed differentially early during lung carcinogenesis Lung Cancer. 41: S159-S160. DOI: 10.1016/S0169-5002(03)92236-7 |
0.39 |
|
2002 |
Kim KB, Lotan R, Yue P, Sporn MB, Suh N, Gribble GW, Honda T, Wu GS, Hong WK, Sun SY. Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells. Molecular Cancer Therapeutics. 1: 177-84. PMID 12467212 |
0.37 |
|
2002 |
Wu W, Tang X, Hu W, Lotan R, Hong WK, Mao L. Identification and validation of metastasis-associated proteins in head and neck cancer cell lines by two-dimensional electrophoresis and mass spectrometry. Clinical & Experimental Metastasis. 19: 319-26. PMID 12090472 DOI: 10.1023/A:1015515119300 |
0.367 |
|
2002 |
Guan B, Yue P, Lotan R, Sun SY. Evidence that the human death receptor 4 is regulated by activator protein 1. Oncogene. 21: 3121-9. PMID 12082627 DOI: 10.1038/Sj.Onc.1205430 |
0.357 |
|
2002 |
Sun SY, Yue P, Chen X, Hong WK, Lotan R. The synthetic retinoid CD437 selectively induces apoptosis in human lung cancer cells while sparing normal human lung epithelial cells. Cancer Research. 62: 2430-6. PMID 11956107 |
0.374 |
|
2002 |
Shureiqi I, Jiang W, Fischer SM, Xu X, Chen D, Lee JJ, Lotan R, Lippman SM. GATA-6 transcriptional regulation of 15-lipoxygenase-1 during NSAID-induced apoptosis in colorectal cancer cells. Cancer Research. 62: 1178-83. PMID 11861401 |
0.329 |
|
2002 |
Li M, Song S, Lippman SM, Zhang XK, Liu X, Lotan R, Xu XC. Induction of retinoic acid receptor-beta suppresses cyclooxygenase-2 expression in esophageal cancer cells. Oncogene. 21: 411-8. PMID 11821953 DOI: 10.1038/Sj.Onc.1205106 |
0.364 |
|
2002 |
Sun SY, Lotan R. Retinoids and their receptors in cancer development and chemoprevention. Critical Reviews in Oncology/Hematology. 41: 41-55. PMID 11796231 DOI: 10.1016/S1040-8428(01)00144-5 |
0.449 |
|
2002 |
Shin DM, Glisson BS, Khuri FR, Clifford JL, Clayman G, Benner SE, Forastiere AA, Ginsberg L, Liu D, Lee JJ, Myers J, Goepfert H, Lotan R, Hong WK, Lippman SM. Phase II and biologic study of interferon alfa, retinoic acid, and cisplatin in advanced squamous skin cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 20: 364-70. PMID 11786562 DOI: 10.1200/Jco.20.2.364 |
0.347 |
|
2002 |
Hayashi K, Yokozaki H, Goodison S, Oue N, Suzuki T, Lotan R, Yasui W, Tahara E. Inactivation of retinoic acid receptor beta by promoter CpG hypermethylation in gastric cancer. Differentiation; Research in Biological Diversity. 68: 13-21. PMID 11683489 DOI: 10.1046/J.1432-0436.2001.068001013.X |
0.383 |
|
2002 |
Hail N, Lotan R. Mitochondrial respiration is uniquely associated with the prooxidant and apoptotic effects of N-(4-hydroxyphenyl)retinamide. The Journal of Biological Chemistry. 276: 45614-21. PMID 11546781 DOI: 10.1074/Jbc.M106559200 |
0.328 |
|
2001 |
Zou CP, Youssef EM, Zou CC, Carey TE, Lotan R. Differential effects of chromosome 3p deletion on the expression of the putative tumor suppressor RAR beta and on retinoid resistance in human squamous carcinoma cells. Oncogene. 20: 6820-7. PMID 11687961 DOI: 10.1038/Sj.Onc.1204846 |
0.418 |
|
2001 |
Nakashima T, Sun SY, Lotan R, Fujiwara T, Yasumatsu R, Komiyama S, Clayman GL. All-trans-retinoic acid enhances the effect of adenovirus-mediated wild-type p53 gene transfer in head and neck squamous cell carcinoma. The Laryngoscope. 111: 1459-64. PMID 11568584 DOI: 10.1097/00005537-200108000-00024 |
0.408 |
|
2001 |
Lippman SM, Lee JJ, Karp DD, Vokes EE, Benner SE, Goodman GE, Khuri FR, Marks R, Winn RJ, Fry W, Graziano SL, Gandara DR, Okawara G, Woodhouse CL, Williams B, ... ... Lotan R, et al. Randomized phase III intergroup trial of isotretinoin to prevent second primary tumors in stage I non-small-cell lung cancer. Journal of the National Cancer Institute. 93: 605-18. PMID 11309437 DOI: 10.1093/Jnci/93.8.605 |
0.413 |
|
2001 |
Hayashi K, Yokozaki H, Naka K, Yasui W, Lotan R, Tahara E. Overexpression of retinoic acid receptor beta induces growth arrest and apoptosis in oral cancer cell lines. Japanese Journal of Cancer Research : Gann. 92: 42-50. PMID 11173543 DOI: 10.1111/J.1349-7006.2001.Tb01046.X |
0.464 |
|
2001 |
Sun SY, Yue P, Zhou JY, Wang Y, Choi Kim HR, Lotan R, Wu GS. Overexpression of BCL2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cells. Biochemical and Biophysical Research Communications. 280: 788-97. PMID 11162590 DOI: 10.1006/Bbrc.2000.4218 |
0.392 |
|
2001 |
Hail N, Lotan R. Synthetic retinoid CD437 promotes rapid apoptosis in malignant human epidermal keratinocytes and G1 arrest in their normal counterparts. Journal of Cellular Physiology. 186: 24-34. PMID 11147811 DOI: 10.1002/1097-4652(200101)186:1<24::Aid-Jcp1006>3.0.Co;2-S |
0.384 |
|
2001 |
ZOU C, LIEBERT M, ZOU C, GROSSMAN HB, LOTAN R. IDENTIFICATION OF EFFECTIVE RETINOIDS FOR INHIBITING GROWTH AND INDUCING APOPTOSIS IN BLADDER CANCER CELLS Journal of Urology. 165: 986-992. DOI: 10.1016/S0022-5347(05)66589-5 |
0.48 |
|
2000 |
Sun SY, Yue P, Lotan R. Implication of multiple mechanisms in apoptosis induced by the synthetic retinoid CD437 in human prostate carcinoma cells. Oncogene. 19: 4513-22. PMID 11002424 DOI: 10.1038/Sj.Onc.1203810 |
0.37 |
|
2000 |
Sun SY, Yue P, Chandraratna RA, Tesfaigzi Y, Hong WK, Lotan R. Dual mechanisms of action of the retinoid CD437: nuclear retinoic acid receptor-mediated suppression of squamous differentiation and receptor-independent induction of apoptosis in UMSCC22B human head and neck squamous cell carcinoma cells. Molecular Pharmacology. 58: 508-14. PMID 10953043 DOI: 10.1124/Mol.58.3.508 |
0.381 |
|
2000 |
Khuri FR, Lotan R, Kemp BL, Lippman SM, Wu H, Feng L, Lee JJ, Cooksley CS, Parr B, Chang E, Walsh GL, Lee JS, Hong WK, Xu XC. Retinoic acid receptor-beta as a prognostic indicator in stage I non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 18: 2798-804. PMID 10920126 DOI: 10.1200/Jco.2000.18.15.2798 |
0.409 |
|
2000 |
Shureiqi I, Chen D, Lee JJ, Yang P, Newman RA, Brenner DE, Lotan R, Fischer SM, Lippman SM. 15-LOX-1: a novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells Journal of the National Cancer Institute. 92: 1136-1142. PMID 10904086 DOI: 10.1093/Jnci/92.14.1136 |
0.439 |
|
2000 |
Xu XC, Sola Gallego JJ, Lotan R, El-Naggar AK. Differential expression of galectin-1 and galectin-3 in benign and malignant salivary gland neoplasms. International Journal of Oncology. 17: 271-6. PMID 10891535 DOI: 10.3892/Ijo.17.2.271 |
0.396 |
|
2000 |
Qiu H, Lotan R, Lippman SM, Xu XC. Lack of correlation between expression of retinoic acid receptor-beta and loss of heterozygosity on chromosome band 3p24 in esophageal cancer. Genes, Chromosomes & Cancer. 28: 196-202. PMID 10825004 DOI: 10.1002/(Sici)1098-2264(200006)28:2<196::Aid-Gcc8>3.0.Co;2-L |
0.359 |
|
2000 |
Lu Y, Lotan D, Lotan R. Differential regulation of constitutive and retinoic acid-induced galectin-1 gene transcription in murine embryonal carcinoma and myoblastic cells. Biochimica Et Biophysica Acta. 1491: 13-9. PMID 10760565 DOI: 10.1016/S0167-4781(00)00055-5 |
0.378 |
|
2000 |
Gillenwater A, Zou CP, Zhong M, Lotan R. Effects of sodium butyrate on growth, differentiation, and apoptosis in head and neck squamous carcinoma cell lines. Head & Neck. 22: 247-56. PMID 10748448 DOI: 10.1002/(Sici)1097-0347(200005)22:3<247::Aid-Hed7>3.0.Co;2-O |
0.431 |
|
2000 |
Sun SY, Wan H, Yue P, Hong WK, Lotan R. Evidence that retinoic acid receptor beta induction by retinoids is important for tumor cell growth inhibition. The Journal of Biological Chemistry. 275: 17149-53. PMID 10747926 DOI: 10.1074/Jbc.M000527200 |
0.473 |
|
2000 |
Hayashi K, Yokozaki H, Naka K, Yasui W, Yajin K, Lotan R, Tahara E. Effect of 9-cis-retinoic acid on oral squamous cell carcinoma cell lines. Cancer Letters. 151: 199-208. PMID 10738115 DOI: 10.1016/S0304-3835(99)00422-X |
0.428 |
|
2000 |
Lippman SM, Lotan R. Advances in the development of retinoids as chemopreventive agents. The Journal of Nutrition. 130: 479S-482S. PMID 10721933 DOI: 10.1093/Jn/130.2.479S |
0.337 |
|
2000 |
Lotan Y, Xu XC, Shalev M, Lotan R, Williams R, Wheeler TM, Thompson TC, Kadmon D. Differential expression of nuclear retinoid receptors in normal and malignant prostates. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 18: 116-21. PMID 10623701 DOI: 10.1200/Jco.2000.18.1.116 |
0.328 |
|
2000 |
Suzuki S, Higuchi M, Proske RJ, Oridate N, Hong WK, Lotan R. Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells. Oncogene. 18: 6380-7. PMID 10597238 DOI: 10.1038/Sj.Onc.1203024 |
0.354 |
|
2000 |
Heintzelman DL, Lotan R, Richards-Kortum RR. Characterization of the Autofluorescence of Polymorphonuclear Leukocytes, Mononuclear Leukocytes and Cervical Epithelial Cancer Cells for Improved Spectroscopic Discrimination of Inflammation from Dysplasia Photochemistry and Photobiology. 71: 327-332. DOI: 10.1562/0031-8655(2000)0710327Cotaop2.0.Co2 |
0.356 |
|
1999 |
Qiu H, Zhang W, El-Naggar AK, Lippman SM, Lin P, Lotan R, Xu XC. Loss of Retinoic Acid Receptor-β Expression Is an Early Event during Esophageal Carcinogenesis American Journal of Pathology. 155: 1519-1523. PMID 10550308 DOI: 10.1016/S0002-9440(10)65467-3 |
0.349 |
|
1999 |
Sun SY, Yue P, Shroot B, Hong WK, Lotan R. Implication of c-Myc in apoptosis induced by the retinoid CD437 in human lung carcinoma cells. Oncogene. 18: 3894-901. PMID 10445853 DOI: 10.1038/Sj.Onc.1202771 |
0.405 |
|
1999 |
Xu XC, Lee JS, Lee JJ, Morice RC, Liu X, Lippman SM, Hong WK, Lotan R. Nuclear retinoid acid receptor beta in bronchial epithelium of smokers before and during chemoprevention. Journal of the National Cancer Institute. 91: 1317-21. PMID 10433621 DOI: 10.1093/Jnci/91.15.1317 |
0.376 |
|
1999 |
Lotan R. Aberrant expression of retinoid receptors and lung carcinogenesis. Journal of the National Cancer Institute. 91: 989-91. PMID 10379957 DOI: 10.1093/Jnci/91.12.989 |
0.49 |
|
1999 |
Sun SY, Yue P, Wu GS, El-Deiry WS, Shroot B, Hong WK, Lotan R. Mechanisms of apoptosis induced by the synthetic retinoid CD437 in human non-small cell lung carcinoma cells. Oncogene. 18: 2357-65. PMID 10327056 DOI: 10.1038/Sj.Onc.1202543 |
0.41 |
|
1999 |
Zou CP, Hong WK, Lotan R. Expression of retinoic acid receptor β is associated with inhibition of keratinization in human head and neck squamous carcinoma cells Differentiation. 64: 123-132. PMID 10234809 DOI: 10.1046/J.1432-0436.1999.6420123.X |
0.421 |
|
1999 |
Lu Y, Lotan R. Transcriptional regulation by butyrate of mouse galectin-1 gene in embryonal carcinoma cells. Biochimica Et Biophysica Acta. 1444: 85-91. PMID 9931450 DOI: 10.1016/S0167-4781(98)00257-7 |
0.337 |
|
1999 |
Ellerhorst J, Nguyen T, Cooper DN, Estrov Y, Lotan D, Lotan R. Induction of differentiation and apoptosis in the prostate cancer cell line LNCaP by sodium butyrate and galectin-1. International Journal of Oncology. 14: 225-32. PMID 9917496 DOI: 10.3892/Ijo.14.2.225 |
0.434 |
|
1999 |
Lotan R. Lung cancer promotion by beta-carotene and tobacco smoke: relationship to suppression of retinoic acid receptor-beta and increased activator protein-1? Journal of the National Cancer Institute. 91: 7-9. PMID 9890162 DOI: 10.1093/Jnci/91.1.7 |
0.353 |
|
1999 |
Cheng Y, Lotan R. Molecular cloning and characterization of a novel retinoic acid-inducible gene that encodes a putative G protein-coupled receptor. The Journal of Biological Chemistry. 273: 35008-15. PMID 9857033 DOI: 10.1074/Jbc.273.52.35008 |
0.455 |
|
1999 |
Ellerhorst J, Nguyen T, Cooper DNW, Lotan D, Lotan R. Differential expression of endogenous galectin-1 and galectin-3 in human prostate cancer cell lines and effects of overexpressing galectin-1 on cell phenotype. International Journal of Oncology. 14: 217-241. DOI: 10.3892/Ijo.14.2.217 |
0.39 |
|
1999 |
Yazdi Y, Ramanujam N, Lotan R, Mitchell MF, Hittelman WN, Richards-Kortum R. Resonance Raman Spectroscopy at 257 nm Excitation of Normal and Malignant Cultured Breast and Cervical Cells Applied Spectroscopy. 53: 82-85. DOI: 10.1366/0003702991945254 |
0.347 |
|
1998 |
Lu Y, Amos B, Cruise E, Lotan D, Lotan R. A parallel association between differentiation and induction of galectin-1, and inhibition of galectin-3 by retinoic acid in mouse embryonal carcinoma F9 cells. Biological Chemistry. 379: 1323-31. PMID 9865605 DOI: 10.1515/Bchm.1998.379.11.1323 |
0.361 |
|
1998 |
Zou C, Wang L, Liebert M, Grossman HB, Lotan R, Wei Q. Combined effect of chemopreventive agent N-(4-hydroxyphenyl) retinamide (4-HPR) and gamma-radiation on bladder cancer cell lines. International Journal of Oncology. 13: 1037-41. PMID 9772297 DOI: 10.3892/Ijo.13.5.1037 |
0.417 |
|
1998 |
Wan H, Dawson MI, Hong WK, Lotan R. Overexpressed activated retinoid X receptors can mediate growth inhibitory effects of retinoids in human carcinoma cells Journal of Biological Chemistry. 273: 26915-26922. PMID 9756939 DOI: 10.1074/Jbc.273.41.26915 |
0.387 |
|
1998 |
Bernacki SH, Medvedev A, Holloway G, Dawson M, Lotan R, Jetten AM. Suppression Of Relaxin Gene Expression By Retinoids In Squamous Differentiated Rabbit Tracheal Epithelial Cells Molecular and Cellular Endocrinology. 138: 115-125. PMID 9685220 DOI: 10.1016/S0303-7207(98)00013-6 |
0.401 |
|
1998 |
Biesalski HK, Bueno de Mesquita B, Chesson A, Chytil F, Grimble R, Hermus RJ, Köhrle J, Lotan R, Norpoth K, Pastorino U, Thurnham D. European Consensus Statement on Lung Cancer: risk factors and prevention. Lung Cancer Panel. Ca: a Cancer Journal For Clinicians. 48: 167-76; discussion 1. PMID 9594919 DOI: 10.3322/Canjclin.48.3.167 |
0.367 |
|
1998 |
Gillenwater A, Xu XC, Estrov Y, Sacks PG, Lotan D, Lotan R. Modulation of galectin-1 content in human head and neck squamous carcinoma cells by sodium butyrate. International Journal of Cancer. Journal International Du Cancer. 75: 217-24. PMID 9462711 DOI: 10.1002/(Sici)1097-0215(19980119)75:2<217::Aid-Ijc9>3.0.Co;2-X |
0.444 |
|
1998 |
Lotan R. Retinoids and chemoprevention of aerodigestive tract cancers. Cancer Metastasis Reviews. 16: 349-56. PMID 9433644 DOI: 10.1023/A:1005808429176 |
0.454 |
|
1997 |
Biesalski HK, Bueno de Mesquita B, Chesson A, Chytil F, Grinble R, Hermus RI, Köhrle J, Lotan R, Norpoth K, Pastorino U, Thurnham D. Consensus statement on lung cancer. Lung Cancer Panel. European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (Ecp). 6: 316-22. PMID 9370093 DOI: 10.1097/00008469-199708000-00002 |
0.379 |
|
1997 |
Wan H, Dawson MI, Hong WK, Lotan R. Enhancement of Calu-1 human lung carcinoma cell growth in serum-free medium by retinoids: Dependence on AP-1 activation, but not on retinoid response element activation Oncogene. 15: 2109-2118. PMID 9366527 DOI: 10.1038/Sj.Onc.1201381 |
0.44 |
|
1997 |
Sun SY, Yue P, Shroot B, Hong WK, Lotan R. Induction of apoptosis in human non-small cell lung carcinoma cells by the novel synthetic retinoid CD437. Journal of Cellular Physiology. 173: 279-84. PMID 9365537 DOI: 10.1002/(Sici)1097-4652(199711)173:2<279::Aid-Jcp36>3.0.Co;2-8 |
0.45 |
|
1997 |
Naka K, Yokozaki H, Domen T, Hayashi K, Kuniyasu H, Yasui W, Lotan R, Tahara E. Growth inhibition of cultured human gastric cancer cells by 9-cis-retinoic acid with induction of cdk inhibitor Waf1/Cip1/Sdi1/p21 protein. Differentiation; Research in Biological Diversity. 61: 313-20. PMID 9342842 DOI: 10.1046/J.1432-0436.1997.6150313.X |
0.431 |
|
1997 |
Oridate N, Suzuki S, Higuchi M, Mitchell MF, Hong WK, Lotan R. Involvement of Reactive Oxygen Species in N-(4-Hydroxyphenyl)retinamide-Induced Apoptosis in Cervical Carcinoma Cells Journal of the National Cancer Institute. 89: 1191-1198. PMID 9274913 DOI: 10.1093/Jnci/89.16.1191 |
0.388 |
|
1997 |
Lotan R. Roles of retinoids and their nuclear receptors in the development and prevention of upper aerodigestive tract cancers. Environmental Health Perspectives. 985-8. PMID 9255592 DOI: 10.1289/Ehp.97105S4985 |
0.453 |
|
1997 |
Papadimitrakopoulou V, Izzo J, Lippman SM, Lee JS, Fan YH, Clayman G, Ro JY, Hittelman WN, Lotan R, Hong WK, Mao L. Frequent inactivation of p16INK4a in oral premalignant lesions. Oncogene. 14: 1799-803. PMID 9150385 DOI: 10.1038/Sj.Onc.1201010 |
0.302 |
|
1997 |
Xu XC, Sozzi G, Lee JS, Lee JJ, Pastorino U, Pilotti S, Kurie JM, Hong WK, Lotan R. Suppression of retinoic acid receptor beta in non-small-cell lung cancer in vivo: implications for lung cancer development. Journal of the National Cancer Institute. 89: 624-9. PMID 9150186 DOI: 10.1093/Jnci/89.9.624 |
0.502 |
|
1997 |
Oridate N, Higuchi M, Suzuki S, Shroot B, Hong WK, Lotan R. Rapid induction of apoptosis in human C33A cervical carcinoma cells by the synthetic retinoid 6-[3-(1-adamantyl)hydroxyphenyl]-2-naphtalene carboxylic acid (CD437). International Journal of Cancer. 70: 484-7. PMID 9033662 DOI: 10.1002/(Sici)1097-0215(19970207)70:4<484::Aid-Ijc21>3.0.Co;2-E |
0.338 |
|
1997 |
Khuri FR, Lippman SM, Spitz MR, Lotan R, Hong WK. Molecular epidemiology and retinoid chemoprevention of head and neck cancer Journal of the National Cancer Institute. 89: 199-211. PMID 9017000 DOI: 10.1093/Jnci/89.3.199 |
0.376 |
|
1997 |
Eicher SA, Lotan R. Differential effects of retinoic acid and N-(4-hydroxyphenyl)retinamide on head and neck squamous cell carcinoma cells. The Laryngoscope. 106: 1471-5. PMID 8948605 DOI: 10.1097/00005537-199612000-00005 |
0.442 |
|
1997 |
Gillenwater A, Xu XC, el-Naggar AK, Clayman GL, Lotan R. Expression of galectins in head and neck squamous cell carcinoma. Head & Neck. 18: 422-32. PMID 8864733 DOI: 10.1002/(Sici)1097-0347(199609/10)18:5<422::Aid-Hed5>3.0.Co;2-7 |
0.399 |
|
1997 |
ORIDATE N, FUKUDA S, INUYAMA Y, LOTAN R. Reconstituted basement membrane (Matrigel) as a useful semisolid medium for growth of head and neck squamous carcinoma cell colonies. Japanese Jornal of Head and Neck Cancer. 23: 137-139. DOI: 10.5981/Jjhnc1974.23.137 |
0.326 |
|
1997 |
Lotan R. Retinoids and their nuclear receptors in the development, prevention, and treatment of upper airways epithelial cancers Lung Cancer. 18: 12-13. DOI: 10.1016/S0169-5002(97)83861-5 |
0.516 |
|
1997 |
Mitchell MF, Tortolero-Luna G, Lee JJ, Hittelman WK, Lotan R, Wharton JT, Hong WK, Nishioka K. Polyamine measurements in the uterine cervix Journal of Cellular Biochemistry. 67: 125-132. DOI: 10.1002/(Sici)1097-4644(1997)28/29+<125::Aid-Jcb14>3.0.Co;2-G |
0.315 |
|
1996 |
Sacks PG, Amos B, Lotan R. Enhancement of glycosylation of cellular glycoconjugates in the squamous carcinoma cell line MDA886Ln by beta-all-trans retinoic acid. Glycoconjugate Journal. 13: 791-6. PMID 8910006 DOI: 10.1007/Bf00702343 |
0.358 |
|
1996 |
Lotan R. Retinoids in cancer chemoprevention. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 10: 1031-9. PMID 8801164 DOI: 10.1096/Fasebj.10.9.8801164 |
0.448 |
|
1996 |
Oridate N, Lotan R, Lotan D. Reconstituted basement membrane (Matrigel): a useful semisolid medium for growth of tumor cell colonies. In Vitro Cellular & Developmental Biology. Animal. 32: 192-3. PMID 8727041 DOI: 10.1007/Bf02722944 |
0.306 |
|
1996 |
Mitchell MF, Hittelman WK, Lotan R, Nishioka K, Tortolero-Luna G, Richards-Kortum R, Wharton JT, Hong WK. Chemoprevention trials and surrogate end point biomarkers in the cervix. Cancer. 76: 1956-77. PMID 8634987 DOI: 10.1002/1097-0142(19951115)76:10+<1956::Aid-Cncr2820761312>3.0.Co;2-V |
0.313 |
|
1995 |
Lotan R, Xu XC, Lippman SM, Ro JY, Lee JS, Lee JJ, Hong WK. Suppression of retinoic acid receptor-beta in premalignant oral lesions and its up-regulation by isotretinoin. The New England Journal of Medicine. 332: 1405-10. PMID 7723796 DOI: 10.1056/Nejm199505253322103 |
0.354 |
|
1995 |
Lotan R, Belloni PN, Tressler RJ, Lotan D, Xu XC, Nicolson GL. Expression of galectins on microvessel endothelial cells and their involvement in tumour cell adhesion. Glycoconjugate Journal. 11: 462-8. PMID 7696849 DOI: 10.1007/Bf00731282 |
0.391 |
|
1995 |
Lotan R. Retinoids and apoptosis: implications for cancer chemoprevention and therapy. Journal of the National Cancer Institute. 87: 1655-7. PMID 7473809 DOI: 10.1093/Jnci/87.22.1655 |
0.439 |
|
1994 |
Lippman SM, Glisson BS, Kavanagh JJ, Lotan R, Hong WK, Paredes-Espinoza M, Hittelman WN, Holdener EE, Krakoff IH. Retinoic acid and interferon combination studies in human cancer. European Journal of Cancer (Oxford, England : 1990). S9-13. PMID 8260265 DOI: 10.1016/0959-8049(93)90618-P |
0.415 |
|
1994 |
Lotan R, Ito H, Yasui W, Yokozaki H, Lotan D, Tahara E. Expression of a 31-kDa lactoside-binding lectin in normal human gastric mucosa and in primary and metastatic gastric carcinomas. International Journal of Cancer. 56: 474-80. PMID 8112883 DOI: 10.1002/Ijc.2910560404 |
0.315 |
|
1994 |
Xu XC, Clifford JL, Hong WK, Lotan R. Detection of nuclear retinoic acid receptor mRNA in histological tissue sections using nonradioactive in situ hybridization histochemistry Diagnostic Molecular Pathology. 3: 122-131. PMID 7520332 DOI: 10.1097/00019606-199406000-00009 |
0.39 |
|
1993 |
Lotan R. Squamous cell differentiation markers in normal, premalignant, and malignant epithelium: effects of retinoids. Journal of Cellular Biochemistry. Supplement. 167-74. PMID 8412188 DOI: 10.1002/Jcb.240531024 |
0.443 |
|
1993 |
Lee JS, Lippman SM, Hong WK, Ro JY, Lotan R, Hittelman WN. Biomarkers in aerodigestive tract chemoprevention trials Lung Cancer. 9: 361-367. DOI: 10.1016/0169-5002(93)90692-Q |
0.372 |
|
1993 |
Lotan R, Ellerhorst J, Gillenwater A, Amos B, Lotan D, Ohannesian D. S4.6 Expression of lactoside-binding lectins and their cognate glycoconjugates during induced differentiation of cancer cells Glycoconjugate Journal. 10: 246-246. DOI: 10.1007/Bf01209885 |
0.404 |
|
1992 |
Lotan R, Pieniazek J, George MD, Jetten AM. Identification of a new squamous cell differentiation marker and its suppression by retinoids. Journal of Cellular Physiology. 151: 94-102. PMID 1348511 DOI: 10.1002/Jcp.1041510114 |
0.418 |
|
1991 |
Clifford JL, Petkovich M, Chambon P, Lotan R. Modulation by retinoids of mRNA levels for nuclear retinoic acid receptors in murine melanoma cells. Molecular Endocrinology (Baltimore, Md.). 4: 1546-55. PMID 2178220 DOI: 10.1210/Mend-4-10-1546 |
0.351 |
|
1991 |
Lotan R, Matsushita Y, Ohannesian D, Carralero D, Ota DM, Cleary KR, Nicolson GL, Irimura T. Lactose-binding lectin expression in human colorectal carcinomas. Relation to tumor progression. Carbohydrate Research. 213: 47-57. PMID 1933952 DOI: 10.1016/S0008-6215(00)90597-4 |
0.327 |
|
1991 |
Poddar S, Hong WK, Thacher SM, Lotan R. Retinoic acid suppression of squamous differentiation in human head-and-neck squamous carcinoma cells International Journal of Cancer. 48: 239-247. PMID 1708365 DOI: 10.1002/Ijc.2910480215 |
0.417 |
|
1991 |
Lotan R, Clifford J. Nuclear receptors for retinoids: mediators of retinoid effects on normal and malignant cells Biomedicine and Pharmacotherapy. 45: 145-156. PMID 1657236 DOI: 10.1016/0753-3322(91)90102-Y |
0.413 |
|
1990 |
Lotan R, Lotan D, Carralero DM. Modulation of galactoside-binding lectins in tumor cells by differentiation-inducing agents. Cancer Letters. 48: 115-22. PMID 2555043 DOI: 10.1016/0304-3835(89)90046-3 |
0.423 |
|
1990 |
Lippman SM, Lee JS, Lotan R, Hong WK. Chemoprevention of upper aerodigestive tract cancers: A report of the third upper Aerodigestive Cancer Task Force workshop Head and Neck. 12: 5-20. PMID 2404905 DOI: 10.1002/Hed.2880120103 |
0.328 |
|
1990 |
Steck PA, Hadi A, Lotan R, Yung WKA. Inhibition of epidermal growth factor receptor activity by retinoic acid in glioma cells Journal of Cellular Biochemistry. 42: 83-94. PMID 2307713 DOI: 10.1002/Jcb.240420204 |
0.389 |
|
1990 |
Hong WK, Lippman SM, Itri LM, Karp DD, Lee JS, Byers RM, Schantz SP, Kramer AM, Lotan R, Peters LJ. Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck. The New England Journal of Medicine. 323: 795-801. PMID 2202902 DOI: 10.1056/Nejm199009203231205 |
0.359 |
|
1990 |
Amos B, Lotan D, Lotan R. Increased fucosylation of high-molecular-weight glycoproteins accompanies retinoic-acid-induced differentiation of F-9 embryonal carcinoma cells. International Journal of Cancer. 46: 86-94. PMID 2163993 DOI: 10.1002/Ijc.2910460117 |
0.353 |
|
1990 |
Amos B, Lotan R. Retinoid-sensitive cells and cell lines. Methods in Enzymology. 190: 217-25. PMID 2087173 DOI: 10.1016/0076-6879(90)90026-W |
0.362 |
|
1990 |
Lotan R, Lotan D, Sacks PG. Inhibition of tumor cell growth by retinoids. Methods in Enzymology. 190: 100-10. PMID 2087165 DOI: 10.1016/0076-6879(90)90014-R |
0.367 |
|
1990 |
Jetten AM, Kim JS, Sacks PG, Rearick JI, Lotan D, Hong WK, Lotan R. Inhibition of growth and squamous-cell differentiation markers in cultured human head and neck squamous carcinoma cells by beta-all-trans retinoic acid. International Journal of Cancer. Journal International Du Cancer. 45: 195-202. PMID 1967595 DOI: 10.1002/Ijc.2910450135 |
0.408 |
|
1989 |
Sacks PG, Oke V, Vasey T, Lotan R. Retinoic acid inhibition of a head and neck multicellular tumor spheroid model. Head & Neck. 11: 219-25. PMID 2722497 DOI: 10.1002/Hed.2880110305 |
0.35 |
|
1989 |
Sacks PG, Oke V, Amos B, Vasey T, Lotan R. Modulation of growth, differentiation and glycoprotein synthesis by beta-all-trans retinoic acid in a multicellular tumor spheroid model for squamous carcinoma of the head and neck. International Journal of Cancer. Journal International Du Cancer. 44: 926-33. PMID 2479609 DOI: 10.1002/Ijc.2910440530 |
0.369 |
|
1988 |
Lotan R, Raz A. Lectins in cancer cells Annals of the New York Academy of Sciences. 551: 385-398. PMID 3072905 DOI: 10.1111/J.1749-6632.1988.Tb22372.X |
0.394 |
|
1984 |
Meromsky L, Lotan R. Modulation by Retinoic Acid of Cellular, Surface-Exposed, and Secreted Glycoconjugates in Cultured Human Sarcoma Cells Journal of the National Cancer Institute. 72: 203-215. DOI: 10.1093/Jnci/72.2.203 |
0.366 |
|
1980 |
Lotan R, Ong DE, Chytil F. Comparison of the level of cellular retinoid-binding proteins and susceptibility to retinoid-induced growth inhibition of various neoplastic cell lines. Journal of the National Cancer Institute. 64: 1259-62. PMID 6929023 DOI: 10.1093/Jnci/64.5.1259 |
0.392 |
|
1979 |
Dennert G, Crowley C, Kouba J, Lotan R. Retinoic acid stimulation of the induction of mouse killer t-cells in allogeneic and syngeneic systems Journal of the National Cancer Institute. 62: 89-94. PMID 309967 DOI: 10.1093/Jnci/62.1.89 |
0.334 |
|
1978 |
Lotan R, Nicolson GL. Inhibitory effects of retinoic acid or retinyl acetate on the growth of untransformed, transformed, and tumor cells in vitro. Journal of the National Cancer Institute. 59: 1717-22. PMID 562945 DOI: 10.1093/Jnci/59.6.1717 |
0.346 |
|
1978 |
Lotan R, Giotta G, Nork E, Nicolson GL. Characterization of the inhibitory effects of retinoids on the in vitro growth of two malignant murine melanomas. Journal of the National Cancer Institute. 60: 1035-41. PMID 205660 DOI: 10.1093/Jnci/60.5.1035 |
0.371 |
|
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