Charlotte Kuperwasser, Ph.D. - Publications

Affiliations: 
2000 University of Massachusetts, Amherst, Amherst, MA 
Area:
Molecular Biology, Cell Biology

89 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Rauner G, Traugh NC, Trepicchio CJ, Parrish ME, Mushayandebvu K, Kuperwasser C. Advancements in Human Breast Organoid Culture: Modeling Complex Tissue Structures and Developmental Insights. Biorxiv : the Preprint Server For Biology. PMID 37873154 DOI: 10.1101/2023.10.02.560364  0.315
2021 Rauner G, Jin DX, Miller DH, Gierahn TM, Li CM, Sokol ES, Feng YX, Mathis RA, Love JC, Gupta PB, Kuperwasser C. Breast tissue regeneration is driven by cell-matrix interactions coordinating multi-lineage stem cell differentiation through DDR1. Nature Communications. 12: 7116. PMID 34893587 DOI: 10.1038/s41467-021-27401-6  0.347
2019 Zhou W, Gross KM, Kuperwasser C. Molecular regulation of Snai2 in development and disease. Journal of Cell Science. 132. PMID 31792043 DOI: 10.1242/Jcs.235127  0.363
2019 Elman JS, Ni TK, Mengwasser KE, Jin D, Wronski A, Elledge SJ, Kuperwasser C. Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing. Cell Reports. 28: 3435-3449.e5. PMID 31553912 DOI: 10.1016/J.Celrep.2019.08.060  0.394
2019 Gross KM, Zhou W, Breindel JL, Ouyang J, Jin DX, Sokol ES, Gupta PB, Huber K, Zou L, Kuperwasser C. Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium. Cell Reports. 28: 394-407.e6. PMID 31291576 DOI: 10.1016/J.Celrep.2019.06.043  0.328
2018 Gupta PB, Pastushenko I, Skibinski A, Blanpain C, Kuperwasser C. Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance. Cell Stem Cell. PMID 30554963 DOI: 10.1016/J.Stem.2018.11.011  0.387
2018 Montesion M, Williams ZH, Subramanian RP, Kuperwasser C, Coffin JM. Promoter expression of HERV-K (HML-2) provirus-derived sequences is related to LTR sequence variation and polymorphic transcription factor binding sites. Retrovirology. 15: 57. PMID 30126415 DOI: 10.1186/S12977-018-0441-2  0.304
2018 Miller DH, Jin DX, Sokol ES, Cabrera JR, Superville DA, Gorelov RA, Kuperwasser C, Gupta PB. BCL11B Drives Human Mammary Stem Cell Self-Renewal In Vitro by Inhibiting Basal Differentiation. Stem Cell Reports. PMID 29503088 DOI: 10.1016/J.Stemcr.2018.01.036  0.382
2018 Ni TK, Elman JS, Jin DX, Gupta PB, Kuperwasser C. Premature polyadenylation of MAGI3 is associated with diminished N6-methyladenosine in its large internal exon. Scientific Reports. 8: 1415. PMID 29362392 DOI: 10.1038/S41598-018-19916-8  0.496
2017 Golden BO, Griess B, Mir S, Fitzgerald M, Kuperwasser C, Domann F, Teoh-Fitzgerald M. Extracellular superoxide dismutase inhibits hepatocyte growth factor-mediated breast cancer-fibroblast interactions. Oncotarget. 8: 107390-107408. PMID 29296173 DOI: 10.18632/Oncotarget.22379  0.461
2017 Montesion M, Bhardwaj N, Williams ZH, Kuperwasser C, Coffin JM. Mechanisms of HERV-K (HML-2) transcription during human mammary epithelial cell transformation. Journal of Virology. PMID 29046454 DOI: 10.1128/Jvi.01258-17  0.392
2017 Breindel JL, Skibinski A, Sedic M, Wronski-Campos A, Zhou W, Keller PJ, Mills J, Bradner J, Onder T, Kuperwasser C. Epigenetic Reprogramming of Lineage-Committed Human Mammary Epithelial Cells Requires DNMT3A and Loss of DOT1L. Stem Cell Reports. PMID 28781076 DOI: 10.1016/J.Stemcr.2017.06.019  0.436
2017 Zhou W, Ouyang J, Huber K, Kuperwasser C. Abstract PR17: The transcriptional repressor Slug promotes the DNA damage response Molecular Cancer Research. 15. DOI: 10.1158/1557-3125.Dnarepair16-Pr17  0.356
2017 Ni TK, Kuperwasser C. Abstract 4995: Premature polyadenylation causes oncogenic truncations of the tumor suppressor genesBRCA1,LATS1andMAGI3in breast cancer Cancer Research. 77: 4995-4995. DOI: 10.1158/1538-7445.Am2017-4995  0.515
2016 Olsen SN, Wronski A, Castaño Z, Dake B, Malone C, De Raedt T, Enos M, DeRose YS, Zhou W, Guerra S, Loda M, Welm A, Partridge AH, McAllister SS, Kuperwasser C, et al. Loss of RasGAP Tumor Suppressors Underlie the Aggressive Nature of Luminal B Breast Cancers. Cancer Discovery. PMID 27974415 DOI: 10.1158/2159-8290.Cd-16-0520  0.458
2016 Zhou W, Ni TK, Wronski A, Glass B, Skibinski A, Beck A, Kuperwasser C. The SIRT2 Deacetylase Stabilizes Slug to Control Malignancy of Basal-like Breast Cancer. Cell Reports. 17: 1302-1317. PMID 27783945 DOI: 10.1016/J.Celrep.2016.10.006  0.485
2016 Ni TK, Kuperwasser C. Premature polyadenylation of MAGI3 produces a dominantly-ccting Oncogene in human breast cancer. Elife. 5. PMID 27205883 DOI: 10.7554/Elife.14730  0.489
2016 Gross K, Wronski A, Skibinski A, Phillips S, Kuperwasser C. Cell Fate Decisions During Breast Cancer Development. Journal of Developmental Biology. 4: 4. PMID 27110512 DOI: 10.3390/jdb4010004  0.428
2016 Sedic M, Kuperwasser C. BRCA1-hapoinsufficiency: Unraveling the molecular and cellular basis for tissue-specific cancer. Cell Cycle (Georgetown, Tex.). 15: 621-7. PMID 26822887 DOI: 10.1080/15384101.2016.1141841  0.514
2016 Xu K, Tian X, Oh SY, Movassaghi M, Naber SP, Kuperwasser C, Buchsbaum RJ. The fibroblast Tiam1-osteopontin pathway modulates breast cancer invasion and metastasis. Breast Cancer Research : Bcr. 18: 14. PMID 26821678 DOI: 10.1186/S13058-016-0674-8  0.509
2016 Ni TK, Kuperwasser C. Author response: Premature polyadenylation of MAGI3 produces a dominantly-acting oncogene in human breast cancer Elife. DOI: 10.7554/Elife.14730.025  0.456
2016 Ni TK, Kuperwasser C. Abstract A48: Role of premature mRNA cleavage and alternative polyadenylation in driving breast cancer Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Advbc15-A48  0.509
2015 Arendt LM, Kuperwasser C. Working stiff: how obesity boosts cancer risk. Science Translational Medicine. 7: 301fs34. PMID 26290410 DOI: 10.1126/Scitranslmed.Aac9446  0.383
2015 Arendt LM, Kuperwasser C. Form and function: how estrogen and progesterone regulate the mammary epithelial hierarchy. Journal of Mammary Gland Biology and Neoplasia. 20: 9-25. PMID 26188694 DOI: 10.1007/S10911-015-9337-0  0.44
2015 Sedic M, Skibinski A, Brown N, Gallardo M, Mulligan P, Martinez P, Keller PJ, Glover E, Richardson AL, Cowan J, Toland AE, Ravichandran K, Riethman H, Naber SP, Näär AM, ... ... Kuperwasser C, et al. Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence. Nature Communications. 6: 7505. PMID 26106036 DOI: 10.1038/Ncomms8505  0.472
2015 Schubert SM, Arendt LM, Zhou W, Baig S, Walter SR, Buchsbaum RJ, Kuperwasser C, Walt DR. Ultra-sensitive protein detection via Single Molecule Arrays towards early stage cancer monitoring. Scientific Reports. 5: 11034. PMID 26052106 DOI: 10.1038/Srep11034  0.328
2015 Wronski A, Arendt LM, Kuperwasser C. Humanization of the mouse mammary gland. Methods in Molecular Biology (Clifton, N.J.). 1293: 173-86. PMID 26040688 DOI: 10.1007/978-1-4939-2519-3_10  0.411
2015 Mazumdar S, Arendt LM, Phillips S, Sedic M, Kuperwasser C, Gill G. CoREST1 promotes tumor formation and tumor stroma interactions in a mouse model of breast cancer. Plos One. 10: e0121281. PMID 25793264 DOI: 10.1371/Journal.Pone.0121281  0.533
2015 Skibinski A, Kuperwasser C. The origin of breast tumor heterogeneity Oncogene. 34: 5309-5316. PMID 25703331 DOI: 10.1038/Onc.2014.475  0.509
2014 Phillips S, Kuperwasser C. SLUG: Critical regulator of epithelial cell identity in breast development and cancer. Cell Adhesion & Migration. 8: 578-87. PMID 25482617 DOI: 10.4161/19336918.2014.972740  0.534
2014 Arendt LM, St Laurent J, Wronski A, Caballero S, Lyle SR, Naber SP, Kuperwasser C. Human breast progenitor cell numbers are regulated by WNT and TBX3. Plos One. 9: e111442. PMID 25350852 DOI: 10.1371/Journal.Pone.0111442  0.475
2014 Arendt LM, Keller PJ, Skibinski A, Goncalves K, Naber SP, Buchsbaum RJ, Gilmore H, Come SE, Kuperwasser C. Anatomical localization of progenitor cells in human breast tissue reveals enrichment of uncommitted cells within immature lobules. Breast Cancer Research : Bcr. 16: 453. PMID 25315014 DOI: 10.1186/S13058-014-0453-3  0.481
2014 Phillips S, Prat A, Sedic M, Proia T, Wronski A, Mazumdar S, Skibinski A, Shirley SH, Perou CM, Gill G, Gupta PB, Kuperwasser C. Cell-state transitions regulated by SLUG are critical for tissue regeneration and tumor initiation. Stem Cell Reports. 2: 633-47. PMID 24936451 DOI: 10.1016/J.Stemcr.2014.03.008  0.416
2014 Kottakis F, Foltopoulou P, Sanidas I, Keller P, Wronski A, Dake BT, Ezell SA, Shen Z, Naber SP, Hinds PW, McNiel E, Kuperwasser C, Tsichlis PN. NDY1/KDM2B functions as a master regulator of polycomb complexes and controls self-renewal of breast cancer stem cells. Cancer Research. 74: 3935-46. PMID 24853546 DOI: 10.1158/0008-5472.Can-13-2733  0.476
2014 Skibinski A, Breindel JL, Prat A, Galván P, Smith E, Rolfs A, Gupta PB, LaBaer J, Kuperwasser C. The Hippo Transducer TAZ Interacts with the SWI/SNF Complex to Regulate Breast Epithelial Lineage Commitment Cell Reports. 6: 1059-1072. PMID 24613358 DOI: 10.1016/J.Celrep.2014.02.038  0.443
2014 McCready J, Arendt LM, Glover E, Iyer V, Briendel JL, Lyle SR, Naber SP, Jay DG, Kuperwasser C. Pregnancy-associated breast cancers are driven by differences in adipose stromal cells present during lactation. Breast Cancer Research : Bcr. 16: R2. PMID 24405573 DOI: 10.1186/Bcr3594  0.513
2014 Xu K, Tian X, Naber SP, Oh S, Kuperwasser C, Buchsbaum RJ. Abstract 973: Tumor-associated fibroblasts induce long-term changes in breast cancer invasion, cancer stem cell populations, and metastasis through modulation of the Tiam1-ostepontin pathway Cancer Research. 74: 973-973. DOI: 10.1158/1538-7445.Am2014-973  0.525
2013 McLaughlin SK, Olsen SN, Dake B, De Raedt T, Lim E, Bronson RT, Beroukhim R, Polyak K, Brown M, Kuperwasser C, Cichowski K. The RasGAP gene, RASAL2, is a tumor and metastasis suppressor. Cancer Cell. 24: 365-78. PMID 24029233 DOI: 10.1016/J.Ccr.2013.08.004  0.483
2013 Arendt LM, McCready J, Keller PJ, Baker DD, Naber SP, Seewaldt V, Kuperwasser C. Obesity promotes breast cancer by CCL2-mediated macrophage recruitment and angiogenesis. Cancer Research. 73: 6080-93. PMID 23959857 DOI: 10.1158/0008-5472.Can-13-0926  0.431
2013 Goel HL, Pursell B, Chang C, Shaw LM, Mao J, Simin K, Kumar P, Vander Kooi CW, Shultz LD, Greiner DL, Norum JH, Toftgard R, Kuperwasser C, Mercurio AM. GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation. Embo Molecular Medicine. 5: 488-508. PMID 23436775 DOI: 10.1002/Emmm.201202078  0.433
2012 Brown NE, Jeselsohn R, Bihani T, Hu MG, Foltopoulou P, Kuperwasser C, Hinds PW. Cyclin D1 activity regulates autophagy and senescence in the mammary epithelium. Cancer Research. 72: 6477-89. PMID 23041550 DOI: 10.1158/0008-5472.Can-11-4139  0.347
2012 Mueller KL, Madden JM, Zoratti GL, Kuperwasser C, List K, Boerner JL. Fibroblast-secreted hepatocyte growth factor mediates epidermal growth factor receptor tyrosine kinase inhibitor resistance in triple-negative breast cancers through paracrine activation of Met. Breast Cancer Research : Bcr. 14: R104. PMID 22788954 DOI: 10.1186/Bcr3224  0.402
2012 Rudnick JA, Kuperwasser C. Stromal biomarkers in breast cancer development and progression. Clinical & Experimental Metastasis. 29: 663-72. PMID 22684404 DOI: 10.1007/S10585-012-9499-8  0.524
2012 Iyer V, Klebba I, McCready J, Arendt LM, Betancur-Boissel M, Wu MF, Zhang X, Lewis MT, Kuperwasser C. Estrogen promotes ER-negative tumor growth and angiogenesis through mobilization of bone marrow-derived monocytes. Cancer Research. 72: 2705-13. PMID 22467173 DOI: 10.1158/0008-5472.Can-11-3287  0.447
2012 Keller PJ, Arendt LM, Skibinski A, Logvinenko T, Klebba I, Dong S, Smith AE, Prat A, Perou CM, Gilmore H, Schnitt S, Naber SP, Garlick JA, Kuperwasser C. Defining the cellular precursors to human breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 109: 2772-7. PMID 21940501 DOI: 10.1073/Pnas.1017626108  0.539
2011 Keller PJ, Arendt LM, Kuperwasser C. Stem cell maintenance of the mammary gland: it takes two. Cell Stem Cell. 9: 496-7. PMID 22136921 DOI: 10.1016/J.Stem.2011.11.008  0.33
2011 Rudnick JA, Arendt LM, Klebba I, Hinds JW, Iyer V, Gupta PB, Naber SP, Kuperwasser C. Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells. Plos One. 6: e24605. PMID 21957456 DOI: 10.1371/Journal.Pone.0024605  0.549
2011 Gupta PB, Fillmore CM, Jiang G, Shapira SD, Tao K, Kuperwasser C, Lander ES. Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells. Cell. 146: 633-44. PMID 21854987 DOI: 10.1016/J.Cell.2011.07.026  0.456
2011 Hwu D, Boutrus S, Greiner C, DiMeo T, Kuperwasser C, Georgakoudi I. Assessment of the role of circulating breast cancer cells in tumor formation and metastatic potential using in vivo flow cytometry. Journal of Biomedical Optics. 16: 040501. PMID 21529063 DOI: 10.1117/1.3560624  0.511
2011 Chaffer CL, Brueckmann I, Scheel C, Kaestli AJ, Wiggins PA, Rodrigues LO, Brooks M, Reinhardt F, Su Y, Polyak K, Arendt LM, Kuperwasser C, Bierie B, Weinberg RA. Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state. Proceedings of the National Academy of Sciences of the United States of America. 108: 7950-5. PMID 21498687 DOI: 10.1073/Pnas.1102454108  0.39
2011 Proia TA, Keller PJ, Gupta PB, Klebba I, Jones AD, Sedic M, Gilmore H, Tung N, Naber SP, Schnitt S, Lander ES, Kuperwasser C. Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate. Cell Stem Cell. 8: 149-63. PMID 21295272 DOI: 10.1016/J.Stem.2010.12.007  0.544
2011 Proia TA, Keller P, Gupta P, Klebba I, Jones A, Sedic M, Gilmore H, Tung N, Naber S, Schnitt S, Lander E, Kuperwasser C. Abstract 916: BRCA1 mutations impair breast epithelial differentiation through upregulation of the transcriptional repressor Slug Cancer Research. 71: 916-916. DOI: 10.1158/1538-7445.Am2011-916  0.542
2011 Keller PJ, Kuperwasser C. Reply to Maguer-Satta et al.: Revisiting the mammosphere assay Proceedings of the National Academy of Sciences of the United States of America. 108: E1265. DOI: 10.1073/Pnas.1117106108  0.34
2010 Kuperwasser C. The tumor stromal microenvironment as modulator of malignant behavior. Journal of Mammary Gland Biology and Neoplasia. 15: 377-9. PMID 21184152 DOI: 10.1007/S10911-010-9198-5  0.322
2010 Fillmore CM, Gupta PB, Rudnick JA, Caballero S, Keller PJ, Lander ES, Kuperwasser C. Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling. Proceedings of the National Academy of Sciences of the United States of America. 107: 21737-42. PMID 21098263 DOI: 10.1073/Pnas.1007863107  0.522
2010 Keller PJ, Lin AF, Arendt LM, Klebba I, Jones AD, Rudnick JA, DiMeo TA, Gilmore H, Jefferson DM, Graham RA, Naber SP, Schnitt S, Kuperwasser C. Mapping the cellular and molecular heterogeneity of normal and malignant breast tissues and cultured cell lines. Breast Cancer Research : Bcr. 12: R87. PMID 20964822 DOI: 10.1186/Bcr2755  0.444
2010 Xu K, Rajagopal S, Klebba I, Dong S, Ji Y, Liu J, Kuperwasser C, Garlick JA, Naber SP, Buchsbaum RJ. The role of fibroblast Tiam1 in tumor cell invasion and metastasis. Oncogene. 29: 6533-42. PMID 20802514 DOI: 10.1038/Onc.2010.385  0.454
2010 McCready J, Arendt LM, Rudnick JA, Kuperwasser C. The contribution of dynamic stromal remodeling during mammary development to breast carcinogenesis. Breast Cancer Research : Bcr. 12: 205. PMID 20584344 DOI: 10.1186/Bcr2578  0.461
2010 Jeselsohn R, Brown NE, Arendt L, Klebba I, Hu MG, Kuperwasser C, Hinds PW. Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis. Cancer Cell. 17: 65-76. PMID 20129248 DOI: 10.1016/J.Ccr.2009.11.024  0.349
2010 Arendt LM, Rudnick JA, Keller PJ, Kuperwasser C. Stroma in breast development and disease. Seminars in Cell & Developmental Biology. 21: 11-8. PMID 19857593 DOI: 10.1016/J.Semcdb.2009.10.003  0.528
2010 Keller PJ, DiMeo TA, Gupta PB, Klebba I, Gilmore H, Tung N, Naber SP, Schnitt S, Lander ES, Kuperwasser C. Abstract LB-265: Mutations in BRCA1 impair breast epithelial differentiation through the transcriptional repressor Slug Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-265  0.551
2009 Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, Weinberg RA, Lander ES. Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell. 138: 645-59. PMID 19682730 DOI: 10.1016/J.Cell.2009.06.034  0.512
2009 DiMeo TA, Anderson K, Phadke P, Fan C, Feng C, Perou CM, Naber S, Kuperwasser C. A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer. Cancer Research. 69: 5364-73. PMID 19549913 DOI: 10.1158/0008-5472.Can-08-4135  0.521
2009 Wu M, Jung L, Cooper AB, Fleet C, Chen L, Breault L, Clark K, Cai Z, Vincent S, Bottega S, Shen Q, Richardson A, Bosenburg M, Naber SP, DePinho RA, ... Kuperwasser C, et al. Dissecting genetic requirements of human breast tumorigenesis in a tissue transgenic model of human breast cancer in mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 7022-7. PMID 19369208 DOI: 10.1073/Pnas.0811785106  0.508
2009 Keller P, Gupta P, Klebba I, Gilmore H, Come S, Schnitt S, Lander E, Kuperwasser C. Breast epithelial differentiation is altered in BRCA1mut/+ carriers prior to the onset of cancer and contributes to the basal tumor phenotype. Cancer Research. 69: 3083. DOI: 10.1158/0008-5472.Sabcs-3083  0.551
2009 Brown NE, Kuperwasser C, Hinds PW. Abstract B26: Lack of cyclin D1 kinase activity leads to reduced levels of ErbB2-induced senescence and activation of the Wnt signaling pathway in the mammary gland Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-B26  0.443
2009 DiMeo TA, Anderson K, Phadke P, Feng C, Perou CM, Naber S, Kuperwasser C. A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer (Cancer Research (2009) 69 (5364-5373)) Cancer Research. 69: 6366. DOI: 10.1158/0008-5472.Can-69-15-Cor2  0.432
2008 Maroulakou IG, Oemler W, Naber SP, Klebba I, Kuperwasser C, Tsichlis PN. Distinct roles of the three Akt isoforms in lactogenic differentiation and involution. Journal of Cellular Physiology. 217: 468-77. PMID 18561256 DOI: 10.1002/Jcp.21518  0.36
2008 Fillmore CM, Kuperwasser C. Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy. Breast Cancer Research : Bcr. 10: R25. PMID 18366788 DOI: 10.1186/Bcr1982  0.479
2007 Paulson KE, Rieger-Christ K, McDevitt MA, Kuperwasser C, Kim J, Unanue VE, Zhang X, Hu M, Ruthazer R, Berasi SP, Huang CY, Giri D, Kaufman S, Dugan JM, Blum J, et al. Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer. Cancer Research. 67: 6136-45. PMID 17616670 DOI: 10.1158/0008-5472.Can-07-0567  0.493
2007 Phung TL, Eyiah-Mensah G, O'Donnell RK, Bieniek R, Shechter S, Walsh K, Kuperwasser C, Benjamin LE. Endothelial Akt signaling is rate-limiting for rapamycin inhibition of mouse mammary tumor progression. Cancer Research. 67: 5070-5. PMID 17545582 DOI: 10.1158/0008-5472.Can-06-3341  0.38
2007 Fillmore C, Kuperwasser C. Human breast cancer stem cell markers CD44 and CD24: enriching for cells with functional properties in mice or in man? Breast Cancer Research : Bcr. 9: 303. PMID 17540049 DOI: 10.1186/Bcr1673  0.506
2007 Boutrus S, Greiner C, Hwu D, Chan M, Kuperwasser C, Lin CP, Georgakoudi I. Portable two-color in vivo flow cytometer for real-time detection of fluorescently-labeled circulating cells. Journal of Biomedical Optics. 12: 020507. PMID 17477705 DOI: 10.1117/1.2722733  0.333
2007 Gupta PB, Proia D, Cingoz O, Weremowicz J, Naber SP, Weinberg RA, Kuperwasser C. Systemic stromal effects of estrogen promote the growth of estrogen receptor-negative cancers. Cancer Research. 67: 2062-71. PMID 17332335 DOI: 10.1158/0008-5472.Can-06-3895  0.49
2007 Huber KE, Wazer DE, Kuperwasser C. The Effect of Radiation on Tumorigenesis and Clonogenic Survival of Breast Cancer Stem Cells International Journal of Radiation Oncology Biology Physics. 69. DOI: 10.1016/J.Ijrobp.2007.07.075  0.456
2006 Proia DA, Kuperwasser C. Reconstruction of human mammary tissues in a mouse model. Nature Protocols. 1: 206-14. PMID 17406234 DOI: 10.1038/Nprot.2006.31  0.47
2006 Gupta PB, Kuperwasser C. Contributions of estrogen to ER-negative breast tumor growth. The Journal of Steroid Biochemistry and Molecular Biology. 102: 71-8. PMID 17049443 DOI: 10.1016/J.Jsbmb.2006.09.025  0.504
2006 DiMeo TA, Kuperwasser C. The evolving paradigm of tissue-specific metastasis. Breast Cancer Research : Bcr. 8: 301. PMID 16417657 DOI: 10.1186/Bcr1373  0.453
2005 Gupta PB, Kuperwasser C, Brunet JP, Ramaswamy S, Kuo WL, Gray JW, Naber SP, Weinberg RA. The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nature Genetics. 37: 1047-54. PMID 16142232 DOI: 10.1038/Ng1634  0.36
2005 Proia DA, Kuperwasser C. Stroma: tumor agonist or antagonist. Cell Cycle (Georgetown, Tex.). 4: 1022-5. PMID 16082203 DOI: 10.4161/Cc.4.8.1903  0.432
2005 Kuperwasser C, Dessain S, Bierbaum BE, Garnet D, Sperandio K, Gauvin GP, Naber SP, Weinberg RA, Rosenblatt M. A mouse model of human breast cancer metastasis to human bone. Cancer Research. 65: 6130-8. PMID 16024614 DOI: 10.1158/0008-5472.Can-04-1408  0.438
2004 Kuperwasser C, Chavarria T, Wu M, Magrane G, Gray JW, Carey L, Richardson A, Weinberg RA. Reconstruction of functionally normal and malignant human breast tissues in mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 4966-71. PMID 15051869 DOI: 10.1073/Pnas.0401064101  0.476
2004 Gupta PB, Kuperwasser C. Disease models of breast cancer Drug Discovery Today: Disease Models. 1: 9-16. DOI: 10.1016/J.Ddmod.2004.05.001  0.441
2000 Kuperwasser C, Hurlbut GD, Kittrell FS, Dickinson ES, Laucirica R, Medina D, Naber SP, Jerry DJ. Development of spontaneous mammary tumors in BALB/c p53 heterozygous mice. A model for Li-Fraumeni syndrome. The American Journal of Pathology. 157: 2151-9. PMID 11106587 DOI: 10.1016/S0002-9440(10)64853-5  0.673
2000 Kuperwasser C, Pinkas J, Hurlbut GD, Naber SP, Jerry DJ. Cytoplasmic sequestration and functional repression of p53 in the mammary epithelium is reversed by hormonal treatment. Cancer Research. 60: 2723-9. PMID 10825147  0.623
2000 Jerry DJ, Kittrell FS, Kuperwasser C, Laucirica R, Dickinson ES, Bonilla PJ, Butel JS, Medina D. A mammary-specific model demonstrates the role of the p53 tumor suppressor gene in tumor development. Oncogene. 19: 1052-8. PMID 10713689 DOI: 10.1038/Sj.Onc.1203270  0.662
1999 Jerry DJ, Pinkas J, Kuperwasser C, Dickinson ES, Naber SP. Regulation of p53 and its targets during involution of the mammary gland. Journal of Mammary Gland Biology and Neoplasia. 4: 177-81. PMID 10426396 DOI: 10.1023/A:1018777224808  0.632
1998 Jerry DJ, Kuperwasser C, Downing SR, Pinkas J, He C, Dickinson E, Marconi S, Naber SP. Delayed involution of the mammary epithelium in BALB/c-p53null mice. Oncogene. 17: 2305-12. PMID 9811461 DOI: 10.1038/Sj.Onc.1202157  0.622
1998 Medina D, Stephens LC, Bonilla PJ, Hollmann CA, Schwahn D, Kuperwasser C, Jerry DJ, Butel JS, Meyn RE. Radiation-induced tumorigenesis in preneoplastic mouse mammary glands in vivo: significance of p53 status and apoptosis. Molecular Carcinogenesis. 22: 199-207. PMID 9688146 DOI: 10.1002/(Sici)1098-2744(199807)22:3<199::Aid-Mc8>3.0.Co;2-G  0.61
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