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Justine E. Roderick, Ph.D. - Publications

Affiliations: 
2011 Animal Science University of Massachusetts, Amherst, Amherst, MA 
Area:
Immunology
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36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Roderick JE, Gallagher KM, Murphy LC, O'Connor KW, Tang K, Zhang B, Brehm MA, Greiner DL, Yu J, Zhu LJ, Green MR, Kelliher MA. Prostaglandin E2 stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death. Blood. 137: 500-512. PMID 33507291 DOI: 10.1182/blood.2020005712  0.433
2020 Roderick JE, Gallagher KM, Murphy LC, O'Connor KW, Tang K, Zhang B, Brehm M, Greiner DL, Yu J, Zhu LJ, Green MR, Kelliher MA. Prostaglandin E2 stimulates cAMP signaling and re-sensitizes human leukemia cells to glucocorticoid-induced cell death. Blood. PMID 32756933 DOI: 10.1182/Blood.2020005712  0.501
2020 Gallagher KM, Roderick JE, Tan SH, Tan TK, Murphy L, Yu J, Li R, O'Connor KW, Zhu J, Green MR, Sanda T, Kelliher MA. ESRRB regulates glucocorticoid gene expression in mice and patients with acute lymphoblastic leukemia. Blood Advances. 4: 3154-3168. PMID 32658986 DOI: 10.1182/Bloodadvances.2020001555  0.422
2019 Pouliot GP, Degar J, Hinze L, Kochupurakkal B, Vo CD, Burns MA, Moreau L, Ganesa C, Roderick J, Peirs S, Menten B, Loh ML, Hunger SP, Silverman LB, Harris MH, et al. Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia. Plos One. 14: e0221288. PMID 31721781 DOI: 10.1371/Journal.Pone.0221288  0.436
2018 Kelliher MA, Roderick JE. NOTCH Signaling in T-Cell-Mediated Anti-Tumor Immunity and T-Cell-Based Immunotherapies. Frontiers in Immunology. 9: 1718. PMID 30967879 DOI: 10.3389/Fimmu.2018.01718  0.473
2018 Dastur A, Choi A, Costa C, Yin X, Williams AF, McClanaghan JD, Greenberg M, Roderick JE, Patel NU, Boisvert JL, McDermott U, Garnett MJ, Almenara J, Grant S, Rizzo K, et al. NOTCH1 represses MCL-1 levels in GSI-resistant T-ALL, making them susceptible to ABT-263. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30224339 DOI: 10.1158/1078-0432.Ccr-18-0867  0.479
2018 Huiting LN, Samaha Y, Zhang GL, Roderick JE, Li B, Anderson NM, Wang YW, Wang L, Laroche F, Choi JW, Liu CT, Kelliher MA, Feng H. UFD1 contributes to MYC-mediated leukemia aggressiveness through suppression of the proapoptotic unfolded protein response. Leukemia. PMID 29743725 DOI: 10.1038/S41375-018-0141-X  0.463
2018 Zelic M, Roderick JE, O'Donnell JA, Lehman J, Lim SE, Janardhan HP, Trivedi CM, Pasparakis M, Kelliher MA. RIP kinase 1-dependent endothelial necroptosis underlies systemic inflammatory response syndrome. The Journal of Clinical Investigation. PMID 29664014 DOI: 10.1172/Jci96147  0.35
2017 O'Donnell JA, Lehman J, Roderick JE, Martinez-Marin D, Zelic M, Doran C, Hermance N, Lyle S, Pasparakis M, Fitzgerald KA, Marshak-Rothstein A, Kelliher MA. Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 29212904 DOI: 10.4049/Jimmunol.1701229  0.396
2017 Choi A, Illendula A, Pulikkan JA, Roderick JE, Tesell J, Yu J, Hermance N, Zhu LJ, Castilla LH, Bushweller JH, Kelliher MA. RUNX1 is required for oncogenic Myb and Myc enhancer activity in T cell acute lymphoblastic leukemia. Blood. PMID 28790107 DOI: 10.1182/Blood-2017-03-775536  0.501
2017 Winter GE, Mayer A, Buckley DL, Erb MA, Roderick JE, Vittori S, Reyes JM, di Iulio J, Souza A, Ott CJ, Roberts JM, Zeid R, Scott TG, Paulk J, Lachance K, et al. BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment. Molecular Cell. PMID 28673542 DOI: 10.1016/J.Molcel.2017.06.004  0.372
2017 Pouliot GP, Burns MA, Degar J, Vo C, Moreau L, Roderick JE, Kochupurakkal B, Peirs S, Menten B, Loh ML, Hunger SP, Silverman LB, Sallan SE, Harris MH, Stevenson KE, et al. The Fanconi Pathway in Pediatric T-Cell Acute Lymphoblastic Leukemia Blood. 130: 2722-2722. DOI: 10.1182/Blood.V130.Suppl_1.2722.2722  0.45
2016 Carr MI, Roderick JE, Zhang H, Woda BA, Kelliher MA, Jones SN. Phosphorylation of the Mdm2 oncoprotein by the c-Abl tyrosine kinase regulates p53 tumor suppression and the radiosensitivity of mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 27956626 DOI: 10.1073/Pnas.1611798114  0.34
2016 Lian H, Li D, Zhou Y, Landesman-Bollag E, Zhang G, Anderson NM, Tang KC, Roderick JE, Kelliher MA, Seldin DC, Fu H, Feng H. CK2 inhibitor CX-4945 destabilizes NOTCH1 and synergizes with JQ1 against human T-acute lymphoblastic leukemic cells. Haematologica. PMID 27758824 DOI: 10.3324/Haematol.2016.154013  0.456
2016 Ma L, Roderick J, Kelliher MA, Green MR. High-Throughput Screening of Tyrosine Kinase Inhibitor Resistant Genes in CML. Methods in Molecular Biology (Clifton, N.J.). 1465: 159-73. PMID 27581147 DOI: 10.1007/978-1-4939-4011-0_14  0.335
2016 Carr MI, Roderick JE, Gannon HS, Kelliher MA, Jones SN. Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis. Cell Reports. PMID 27568562 DOI: 10.1016/J.Celrep.2016.08.014  0.347
2016 Townsend EC, Murakami MA, Christodoulou A, Christie AL, Köster J, DeSouza TA, Morgan EA, Kallgren SP, Liu H, Wu SC, Plana O, Montero J, Stevenson KE, Rao P, Vadhi R, ... ... Roderick JE, et al. The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice. Cancer Cell. 29: 574-86. PMID 27070704 DOI: 10.1016/J.Ccell.2016.03.008  0.309
2016 Anderson NM, Li D, Peng HL, Laroche FJ, Mansour MR, Gjini E, Aioub M, Helman DJ, Roderick JE, Cheng T, Harrold I, Samaha Y, Meng L, Amsterdam A, Neuberg DS, et al. The TCA cycle transferase DLST is important for MYC-mediated leukemogenesis. Leukemia. PMID 26876595 DOI: 10.1038/Leu.2016.26  0.48
2016 Delgado-Martin C, Shimano K, Zinter MS, Wahlstrom JT, Smith GA, Taunton J, Winter SS, Roderick JE, Kelliher M, Horton TM, Wood BL, Teachey DT, Hermiston ML. JAK/STAT Pathway Inhibition Reverts IL7-Induced Glucocorticoid Resistance in a Subset of Human T-Cell Acute Lymphoblastic Leukemia Blood. 128: 3963-3963. DOI: 10.1182/Blood.V128.22.3963.3963  0.431
2016 Roderick JE, Gallagher KM, Tang KM, Kugler-Umana O, Zhu LJ, Green MR, Kelliher M. Identifying Mechanisms of Glucocorticoid Resistance in Relapsed Pediatric T-ALL Blood. 128: 2769-2769. DOI: 10.1182/Blood.V128.22.2769.2769  0.435
2016 O'Donnell J, Roderick JE, Pasparakis M, Kelliher M. IFNγ-Induced Necroptosis Contributes to Hematopoietic Stem and Progenitor Cell Death and Bone Marrow Failure Blood. 128: 1485-1485. DOI: 10.1182/Blood.V128.22.1485.1485  0.314
2015 Letai A, Hogdal L, Chonghaile T, Gutierrez A, Roderick J, Kelliher M, Konopleva M. Abstract IA29: Using mitochondria to guide leukemia therapy. Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Hemmal14-Ia29  0.339
2014 Roderick JE, Hermance N, Zelic M, Simmons MJ, Polykratis A, Pasparakis M, Kelliher MA. Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis. Proceedings of the National Academy of Sciences of the United States of America. 111: 14436-41. PMID 25246544 DOI: 10.1073/Pnas.1409389111  0.421
2014 Wolfe AL, Singh K, Zhong Y, Drewe P, Rajasekhar VK, Sanghvi VR, Mavrakis KJ, Jiang M, Roderick JE, Van der Meulen J, Schatz JH, Rodrigo CM, Zhao C, Rondou P, de Stanchina E, et al. RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer. Nature. 513: 65-70. PMID 25079319 DOI: 10.1038/Nature13485  0.357
2014 Polykratis A, Hermance N, Zelic M, Roderick J, Kim C, Van TM, Lee TH, Chan FK, Pasparakis M, Kelliher MA. Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo. Journal of Immunology (Baltimore, Md. : 1950). 193: 1539-43. PMID 25015821 DOI: 10.4049/Jimmunol.1400590  0.372
2014 Chonghaile TN, Roderick JE, Glenfield C, Ryan J, Sallan SE, Silverman LB, Loh ML, Hunger SP, Wood B, DeAngelo DJ, Stone R, Harris M, Gutierrez A, Kelliher MA, Letai A. Maturation stage of T-cell acute lymphoblastic leukemia determines BCL-2 versus BCL-XL dependence and sensitivity to ABT-199. Cancer Discovery. 4: 1074-87. PMID 24994123 DOI: 10.1158/2159-8290.Cd-14-0353  0.482
2014 Gutierrez A, Roderick JE, Kelliher MA. Leukemia propagating cells Akt up. Cancer Cell. 25: 263-5. PMID 24651006 DOI: 10.1016/J.Ccr.2014.02.022  0.449
2014 Knoechel B, Roderick JE, Williamson KE, Zhu J, Lohr JG, Cotton MJ, Gillespie SM, Fernandez D, Ku M, Wang H, Piccioni F, Silver SJ, Jain M, Pearson D, Kluk MJ, et al. An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia. Nature Genetics. 46: 364-70. PMID 24584072 DOI: 10.1038/Ng.2913  0.54
2014 Reynolds C, Roderick JE, LaBelle JL, Bird G, Mathieu R, Bodaar K, Colon D, Pyati U, Stevenson KE, Qi J, Harris M, Silverman LB, Sallan SE, Bradner JE, Neuberg DS, et al. Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia. Leukemia. 28: 1819-27. PMID 24552990 DOI: 10.1038/Leu.2014.78  0.498
2014 Roderick JE, Tesell J, Shultz LD, Brehm MA, Greiner DL, Harris MH, Silverman LB, Sallan SE, Gutierrez A, Look AT, Qi J, Bradner JE, Kelliher MA. c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells Blood. 123: 1040-1050. PMID 24394663 DOI: 10.1182/Blood-2013-08-522698  0.486
2014 Roderick JE, Hermance N, Zelic M, Simmons M, Polykratis A, Pasparakis M, Kelliher M. Ripk-Mediated Necroptosis Induces Inflammation and Bone Marrow Failure in Mice Blood. 124: 1599-1599. DOI: 10.1182/Blood.V124.21.1599.1599  0.374
2014 Roderick JE, Tesell J, Gutierrez A, Look T, Qi J, Bradner JE, Kelliher MA. Abstract PR02: Targeting NOTCH1 and C-MYC in humanized models of relapsed and induction failure pediatric T-ALL Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-Pr02  0.476
2014 Knoechel B, Roderick J, Williamson K, Zhu J, Lohr J, Cotton M, Gillespie S, Fernandez D, Ku M, Wang H, Piccioni F, Silver S, Jain M, Pearson D, Kluk M, et al. Abstract 4782: Epigenetic resistance to Notch inhibition in T cell acute lymphoblastic leukemia Cancer Research. 74: 4782-4782. DOI: 10.1158/1538-7445.Am2014-4782  0.539
2014 Chonghaile TN, Roderick J, Gutierrez G, Kelliher M, Letai A. 715: BCL-2 dependence in T-cell leukemia is defined by the maturation stage of the clone of origin European Journal of Cancer. 50. DOI: 10.1016/S0959-8049(14)50630-2  0.419
2013 Roderick JE, Gonzalez-Perez G, Kuksin CA, Dongre A, Roberts ER, Srinivasan J, Andrzejewski C, Fauq AH, Golde TE, Miele L, Minter LM. Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia. The Journal of Experimental Medicine. 210: 1311-29. PMID 23733784 DOI: 10.1084/Jem.20112615  0.654
2011 Keerthivasan S, Suleiman R, Lawlor R, Roderick J, Bates T, Minter L, Anguita J, Juncadella I, Nickoloff BJ, Le Poole IC, Miele L, Osborne BA. Notch signaling regulates mouse and human Th17 differentiation. Journal of Immunology (Baltimore, Md. : 1950). 187: 692-701. PMID 21685328 DOI: 10.4049/Jimmunol.1003658  0.617
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