Barbara A. Osborne - Publications

Affiliations: 
University of Massachusetts, Amherst, Amherst, MA 
Area:
Cell Biology, Molecular Biology

112 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mohan D, Sherman HL, Mitra A, Lawlor R, Shanthalingam S, Ullom J, Pobezinskaya EL, Zhang G, Osborne BA, Pobezinsky LA, Tew GN, Minter LM. LKB1 isoform expression modulates T cell plasticity downstream of PKCθ and IL-6. Molecular Immunology. 157: 129-141. PMID 37018939 DOI: 10.1016/j.molimm.2023.03.020  0.372
2022 Monticone G, Huang Z, Csibi F, Leit S, Ciccone D, Champhekar AS, Austin JE, Ucar DA, Hossain F, Ibba SV, Boulares AH, Carpino N, Xu K, Majumder S, Osborne BA, et al. Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses. Frontiers in Immunology. 13: 987298. PMID 36090975 DOI: 10.3389/fimmu.2022.987298  0.322
2020 Ozay EI, Shanthalingam S, Torres JA, Osborne BA, Tew GN, Minter LM. Protein Kinase C Theta Modulates PCMT1 through hnRNPL to Regulate FOXP3 Stability in Regulatory T Cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32592691 DOI: 10.1016/J.Ymthe.2020.06.012  0.472
2020 Ozay EI, Shanthalingam S, Sherman HL, Torres JA, Osborne BA, Tew GN, Minter LM. Cell-Penetrating Anti-Protein Kinase C Theta Antibodies Act Intracellularly to Generate Stable, Highly Suppressive Regulatory T Cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32492367 DOI: 10.1016/J.Ymthe.2020.05.020  0.507
2020 Mitra A, Shanthalingam S, Sherman HL, Singh K, Canakci M, Torres JA, Lawlor R, Ran Y, Golde TE, Miele L, Thayumanavan S, Minter LM, Osborne BA. CD28 Signaling Drives Notch Ligand Expression on CD4 T Cells. Frontiers in Immunology. 11: 735. PMID 32457739 DOI: 10.3389/Fimmu.2020.00735  0.475
2020 Lessard CB, Rodriguez E, Ladd TB, Minter LM, Osborne BA, Miele L, Golde TE, Ran Y. γ-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse γ-secretase modulators do not. Alzheimer's Research & Therapy. 12: 61. PMID 32430033 DOI: 10.1186/S13195-020-00622-5  0.311
2020 Canakci M, Singh K, Munkhbat O, Santhalingam S, Mitra A, Gordon M, Osborne BA, Thayumanavan S. Targeting CD4+ Cells with Anti-CD4 Conjugated Mertansine Loaded Nanogels. Biomacromolecules. PMID 32383874 DOI: 10.1021/Acs.Biomac.0C00442  0.393
2020 Ucar DA, Monticone G, Hossain F, Majumder S, Wyczechowska D, Dean MJ, Valle LD, Zabaleta J, Ran Y, Shanthalingam S, Chabot AB, Collins-Burow BM, Burrow ME, Osborne B, Golde TE, et al. Abstract 6691: Delivering intra-tumoral immune modulators and targeting cancer stem cells using recombinant- AAVs Immunology. 80: 6691-6691. DOI: 10.1158/1538-7445.Am2020-6691  0.379
2020 Monticone G, Hossain FM, Ucar DA, Majumder S, Sorrentino C, Rodriguez PC, Sierra RA, Pannuti A, Hatfield S, Osborne BA, Minter LM, Morello S, Miele L. Abstract 4517: Targeting Notch1 via adenosine A2A receptor to modulate tumor immunity Immunology. 80: 4517-4517. DOI: 10.1158/1538-7445.Am2020-4517  0.505
2019 Lessard CB, Rodriguez E, Ladd TB, Minter LM, Osborne BA, Miele L, Golde TE, Ran Y. Individual and combined presenilin 1 and 2 knockouts reveal that both have highly overlapping functions in HEK293T cells. The Journal of Biological Chemistry. PMID 31167792 DOI: 10.1074/Jbc.Ra119.008041  0.37
2019 Geiger S, Ozay EI, Geumann U, Hereth MK, Magnusson T, Shanthalingam S, Hirsch D, Kälin S, Günther C, Osborne BA, Tew GN, Hermann FG, Minter LM. Alpha-1 Antitrypsin-Expressing Mesenchymal Stromal Cells Confer a Long-Term Survival Benefit in a Mouse Model of Lethal GvHD. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31138510 DOI: 10.1016/J.Ymthe.2019.05.007  0.319
2019 Sorrentino C, Hossain F, Rodriguez PC, Sierra RA, Pannuti A, Hatfield S, Osborne BA, Minter LM, Miele L, Morello S. Corrigendum: Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells. Frontiers in Immunology. 10: 935. PMID 31130947 DOI: 10.3389/Fimmu.2019.00935  0.435
2019 Sorrentino C, Hossain F, Rodriguez PC, Sierra RA, Pannuti A, Osborne BA, Minter LM, Miele L, Morello S. Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells. Frontiers in Immunology. 10: 162. PMID 30792717 DOI: 10.3389/Fimmu.2019.00162  0.536
2019 Ozay EI, Vijayaraghavan J, Gonzalez-Perez G, Shanthalingam S, Sherman HL, Garrigan DT, Chandiran K, Torres JA, Osborne BA, Tew GN, Slukvin II, Macdonald RA, Kelly K, Minter LM. Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease. Stem Cell Research. 35: 101401. PMID 30738321 DOI: 10.1016/J.Scr.2019.101401  0.327
2019 Hossain F, Ucar D, Majumder S, Xu K, Ran Y, Minter L, Xi Y, Burow M, Golde T, Osborne B, Miele L. Abstract P6-22-01: Repurposing sulindac sulfide as a notch inhibitor to target cancer stem-like cells in triple negative breast cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P6-22-01  0.404
2018 Hossain F, Sorrentino C, Ucar DA, Peng Y, Matossian M, Wyczechowska D, Crabtree J, Zabaleta J, Morello S, Del Valle L, Burow M, Collins-Burow B, Pannuti A, Minter LM, Golde TE, ... Osborne BA, et al. Notch Signaling Regulates Mitochondrial Metabolism and NF-κB Activity in Triple-Negative Breast Cancer Cells via IKKα-Dependent Non-canonical Pathways. Frontiers in Oncology. 8: 575. PMID 30564555 DOI: 10.3389/Fonc.2018.00575  0.453
2018 Vijayaraghavan J, Osborne BA. Notch and T Cell Function - A Complex Tale. Advances in Experimental Medicine and Biology. 1066: 339-354. PMID 30030835 DOI: 10.1007/978-3-319-89512-3_17  0.464
2018 Hossain F, Majumder S, Ucar DA, Rodriguez PC, Golde TE, Minter LM, Osborne BA, Miele L. Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses. Frontiers in Immunology. 9: 1288. PMID 29915603 DOI: 10.3389/Fimmu.2018.01288  0.42
2018 Wongchana W, Kongkavitoon P, Tangtanatakul P, Sittplangkoon C, Butta P, Chawalitpong S, Pattarakankul T, Osborne BA, Palaga T. Notch signaling regulates the responses of lipopolysaccharide-stimulated macrophages in the presence of immune complexes. Plos One. 13: e0198609. PMID 29889863 DOI: 10.1371/Journal.Pone.0198609  0.613
2018 Chandiran K, Lawlor R, Pannuti A, Perez GG, Srinivasan J, Golde TE, Miele L, Osborne BA, Minter LM. Notch1 primes CD4 T cells for T helper type I differentiation through its early effects on miR-29. Molecular Immunology. 99: 191-198. PMID 29807327 DOI: 10.1016/J.Molimm.2018.05.002  0.439
2018 Hossain F, Sorrentino C, Bilyeu AU, Matossian M, Crabtree J, Pannuti A, Burow M, Golde T, Osborne B, Miele L. Abstract P6-07-06: Targeting cancer stem-like cells metabolism via non-canonical notch signaling pathways in triple negative breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P6-07-06  0.446
2018 Hossain F, Bilyeu ADU, Sorrentino C, Crabtree J, Pannuti A, Matossian M, Burow M, Golde T, Osborne B, Miele L. Abstract 157: Targeting cancer stem-like cells in triple negative breast cancer Cancer Research. 78: 157-157. DOI: 10.1158/1538-7445.Am2018-157  0.437
2017 Sierra RA, Trillo-Tinoco J, Mohamed E, Yu L, Achyut BR, Arbab A, Bradford JW, Osborne BA, Miele L, Rodriguez PC. Anti-Jagged immunotherapy inhibits MDSCs and overcomes tumor-induced tolerance. Cancer Research. PMID 28904063 DOI: 10.1158/0008-5472.Can-17-0357  0.405
2017 Ran Y, Hossain F, Pannuti A, Lessard CB, Ladd GZ, Jung JI, Minter LM, Osborne BA, Miele L, Golde TE. γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct. Embo Molecular Medicine. PMID 28539479 DOI: 10.15252/Emmm.201607265  0.326
2017 Hossain F, Peng Y, Pannuti A, Backus K, Golde T, Osborne B, Miele L. Abstract P5-07-06: A novel non-canonical Notch1-IKKα-mTORC2-AKT pathway maintains survival in triple negative breast cancer cells and cancer stem-like cells Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P5-07-06  0.325
2017 Hossain F, Sorrentino C, Bilyeu A, Crabtree J, Pannuti A, Golde T, Osborne B, Miele L. Abstract 2904: Targeting cancer stem-like cells in triple negative breast cancer cells through non-canonical notch signaling Cancer Research. 77: 2904-2904. DOI: 10.1158/1538-7445.Am2017-2904  0.458
2016 Wang Y, Yu S, Huang D, Cui M, Hu H, Zhang L, Wang W, Parameswaran N, Jackson M, Osborne B, Bedogni B, Li C, Sy MS, Xin W, Zhou L. Cellular Prion Protein Mediates Pancreatic Cancer Cell Survival and Invasion through Association with and Enhanced Signaling of Notch1. The American Journal of Pathology. PMID 27639164 DOI: 10.1016/J.Ajpath.2016.07.010  0.389
2016 Ozay EI, Gonzalez-Perez G, Torres JA, Vijayaraghavan J, Lawlor R, Sherman HL, Garrigan DT, Burnside AS, Osborne BA, Tew GN, Minter LM. Intracellular delivery of anti-pPKCθ (Thr538) via protein transduction domain mimics for immunomodulation. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27633441 DOI: 10.1038/Mt.2016.177  0.386
2016 Hossain F, Peng Y, Pannuti A, Backus K, Golde TE, Osborne B, Miele L. Abstract 4616: A novel non-canonical Notch-AKT- NF-κB pathways in triple negative breast cancer cells Cancer Research. 76: 4616-4616. DOI: 10.1158/1538-7445.Am2016-4616  0.472
2015 Wongchana W, Lawlor RG, Osborne BA, Palaga T. Impact of Notch1 Deletion in Macrophages on Proinflammatory Cytokine Production and the Outcome of Experimental Autoimmune Encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 195: 5337-46. PMID 26503951 DOI: 10.4049/Jimmunol.1401770  0.613
2015 Yun J, Espinoza I, Pannuti A, Romero D, Martinez L, Caskey M, Stanculescu A, Bocchetta M, Rizzo P, Band V, Band H, Kim HM, Park SK, Kang KW, Avantaggiati ML, ... ... Osborne B, et al. p53 Modulates Notch Signaling in MCF-7 Breast Cancer Cells by Associating with the Notch Transcriptional Complex via MAML1. Journal of Cellular Physiology. PMID 26033683 DOI: 10.1002/Jcp.25052  0.392
2015 Navasa N, Martín I, Iglesias-Pedraz JM, Beraza N, Atondo E, Izadi H, Ayaz F, Fernández-Álvarez S, Hatle K, Som A, Dienz O, Osborne BA, Martínez-Chantar ML, Rincón M, Anguita J. Regulation of oxidative stress by methylation-controlled J protein controls macrophage responses to inflammatory insults. The Journal of Infectious Diseases. 211: 135-45. PMID 25028693 DOI: 10.1093/Infdis/Jiu389  0.312
2014 Ayaz F, Osborne BA. Non-canonical notch signaling in cancer and immunity. Frontiers in Oncology. 4: 345. PMID 25538890 DOI: 10.3389/Fonc.2014.00345  0.428
2014 Shin HM, Tilahun ME, Cho OH, Chandiran K, Kuksin CA, Keerthivasan S, Fauq AH, Golde TE, Miele L, Thome M, Osborne BA, Minter LM. NOTCH1 Can Initiate NF-κB Activation via Cytosolic Interactions with Components of the T Cell Signalosome. Frontiers in Immunology. 5: 249. PMID 24904593 DOI: 10.3389/Fimmu.2014.00249  0.818
2014 Sangphech N, Osborne BA, Palaga T. Notch signaling regulates the phosphorylation of Akt and survival of lipopolysaccharide-activated macrophages via regulator of G protein signaling 19 (RGS19). Immunobiology. 219: 653-60. PMID 24775271 DOI: 10.1016/J.Imbio.2014.03.020  0.65
2014 Dongre A, Surampudi L, Lawlor RG, Fauq AH, Miele L, Golde TE, Minter LM, Osborne BA. Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells. Frontiers in Immunology. 5: 54. PMID 24611064 DOI: 10.3389/Fimmu.2014.00054  0.548
2013 Tezgel AÖ, Gonzalez-Perez G, Telfer JC, Osborne BA, Minter LM, Tew GN. Novel protein transduction domain mimics as nonviral delivery vectors for siRNA targeting NOTCH1 in primary human T cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 201-9. PMID 23070119 DOI: 10.1038/Mt.2012.209  0.436
2012 Minter LM, Osborne BA. Notch and the survival of regulatory T cells: location is everything! Science Signaling. 5: pe31. PMID 22827995 DOI: 10.1126/Scisignal.2003358  0.508
2012 Minter LM, Osborne BA. Canonical and non-canonical Notch signaling in CD4⁺ T cells. Current Topics in Microbiology and Immunology. 360: 99-114. PMID 22695917 DOI: 10.1007/82_2012_233  0.513
2012 Gu JW, Rizzo P, Pannuti A, Golde T, Osborne B, Miele L. Notch signals in the endothelium and cancer "stem-like" cells: opportunities for cancer therapy. Vascular Cell. 4: 7. PMID 22487493 DOI: 10.1186/2045-824X-4-7  0.337
2011 Tilahun ME, Kwan A, Natarajan K, Quinn M, Tilahun AY, Xie C, Margulies DH, Osborne BA, Goldsby RA, Rajagopalan G. Chimeric anti-staphylococcal enterotoxin B antibodies and lovastatin act synergistically to provide in vivo protection against lethal doses of SEB. Plos One. 6: e27203. PMID 22102880 DOI: 10.1371/Journal.Pone.0027203  0.383
2011 Keerthivasan S, Suleiman R, Lawlor R, Roderick J, Bates T, Minter L, Anguita J, Juncadella I, Nickoloff BJ, Le Poole IC, Miele L, Osborne BA. Notch signaling regulates mouse and human Th17 differentiation. Journal of Immunology (Baltimore, Md. : 1950). 187: 692-701. PMID 21685328 DOI: 10.4049/Jimmunol.1003658  0.693
2011 Osborne BA. Notch, a T-ALL order. Blood. 117: 2749-50. PMID 21393498 DOI: 10.1182/Blood-2011-01-330225  0.393
2010 Juncadella IJ, Bates TC, Suleiman R, Monteagudo-Mera A, Olson CM, Navasa N, Olivera ER, Osborne BA, Anguita J. The tick saliva immunosuppressor, Salp15, contributes to Th17-induced pathology during Experimental Autoimmune Encephalomyelitis. Biochemical and Biophysical Research Communications. 402: 105-9. PMID 20920474 DOI: 10.1016/J.Bbrc.2010.09.125  0.711
2010 Pannuti A, Foreman K, Rizzo P, Osipo C, Golde T, Osborne B, Miele L. Targeting Notch to target cancer stem cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 3141-52. PMID 20530696 DOI: 10.1158/1078-0432.Ccr-09-2823  0.342
2010 Tilahun ME, Rajagopalan G, Shah-Mahoney N, Lawlor RG, Tilahun AY, Xie C, Natarajan K, Margulies DH, Ratner DI, Osborne BA, Goldsby RA. Potent neutralization of staphylococcal enterotoxin B by synergistic action of chimeric antibodies. Infection and Immunity. 78: 2801-11. PMID 20308304 DOI: 10.1128/Iai.01121-09  0.4
2010 Hao L, Rizzo P, Osipo C, Pannuti A, Wyatt D, Cheung LW, Sonenshein G, Osborne BA, Miele L. Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells. Oncogene. 29: 201-13. PMID 19838210 DOI: 10.1038/Onc.2009.323  0.367
2009 Wang A, Rud J, Olson CM, Anguita J, Osborne BA. Phosphorylation of Nur77 by the MEK-ERK-RSK cascade induces mitochondrial translocation and apoptosis in T cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 3268-77. PMID 19675165 DOI: 10.4049/Jimmunol.0900894  0.796
2009 Cho OH, Shin HM, Miele L, Golde TE, Fauq A, Minter LM, Osborne BA. Notch regulates cytolytic effector function in CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 3380-9. PMID 19265115 DOI: 10.4049/Jimmunol.0802598  0.812
2009 Osborne BA. B-CLL kicks it up a Notch. Blood. 113: 765-6. PMID 19164502 DOI: 10.1182/Blood-2008-10-182998  0.4
2009 Joshi I, Minter LM, Telfer J, Demarest RM, Capobianco AJ, Aster JC, Sicinski P, Fauq A, Golde TE, Osborne BA. Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases. Blood. 113: 1689-98. PMID 19001083 DOI: 10.1182/Blood-2008-03-147967  0.79
2008 Rizzo P, Osipo C, Foreman K, Golde T, Osborne B, Miele L. Rational targeting of Notch signaling in cancer. Oncogene. 27: 5124-31. PMID 18758481 DOI: 10.1038/Onc.2008.226  0.353
2008 Song LL, Peng Y, Yun J, Rizzo P, Chaturvedi V, Weijzen S, Kast WM, Stone PJ, Santos L, Loredo A, Lendahl U, Sonenshein G, Osborne B, Qin JZ, Pannuti A, et al. Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells. Oncogene. 27: 5833-44. PMID 18560356 DOI: 10.1038/Onc.2008.190  0.48
2008 Samon JB, Champhekar A, Minter LM, Telfer JC, Miele L, Fauq A, Das P, Golde TE, Osborne BA. Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. Blood. 112: 1813-21. PMID 18550850 DOI: 10.1182/Blood-2008-03-144980  0.813
2008 Palaga T, Buranaruk C, Rengpipat S, Fauq AH, Golde TE, Kaufmann SH, Osborne BA. Notch signaling is activated by TLR stimulation and regulates macrophage functions. European Journal of Immunology. 38: 174-83. PMID 18085664 DOI: 10.1002/Eji.200636999  0.67
2008 Osipo C, Golde TE, Osborne BA, Miele LA. Off the beaten pathway: the complex cross talk between Notch and NF-kappaB. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 11-7. PMID 18059366 DOI: 10.1038/Labinvest.3700700  0.374
2007 Izadi H, Motameni AT, Bates TC, Olivera ER, Villar-Suarez V, Joshi I, Garg R, Osborne BA, Davis RJ, Rincón M, Anguita J. c-Jun N-terminal kinase 1 is required for Toll-like receptor 1 gene expression in macrophages. Infection and Immunity. 75: 5027-34. PMID 17664270 DOI: 10.1128/Iai.00492-07  0.73
2007 Osborne BA, Minter LM. Notch signalling during peripheral T-cell activation and differentiation. Nature Reviews. Immunology. 7: 64-75. PMID 17170755 DOI: 10.1038/Nri1998  0.519
2007 Morgan GA, Guo Q, Chan SL, Gary DS, Osborne BA, Mattson MP. Defects of immune regulation in the presenilin-1 mutant knockin mouse. Neuromolecular Medicine. 9: 35-45. PMID 17114823 DOI: 10.1385/Nmm:9:1:35  0.405
2006 Miele L, Golde T, Osborne B. Notch signaling in cancer. Current Molecular Medicine. 6: 905-18. PMID 17168741 DOI: 10.2174/156652406779010830  0.389
2006 Shin HM, Minter LM, Cho OH, Gottipati S, Fauq AH, Golde TE, Sonenshein GE, Osborne BA. Notch1 augments NF-kappaB activity by facilitating its nuclear retention. The Embo Journal. 25: 129-38. PMID 16319921 DOI: 10.1038/Sj.Emboj.7600902  0.769
2005 Granowitz EV, Tonomura N, Benson RM, Katz DM, Band V, Makari-Judson GP, Osborne BA. Hyperbaric oxygen inhibits benign and malignant human mammary epithelial cell proliferation. Anticancer Research. 25: 3833-42. PMID 16312043  0.731
2005 Minter LM, Turley DM, Das P, Shin HM, Joshi I, Lawlor RG, Cho OH, Palaga T, Gottipati S, Telfer JC, Kostura L, Fauq AH, Simpson K, Such KA, Miele L, ... ... Osborne BA, et al. Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nature Immunology. 6: 680-8. PMID 15991363 DOI: 10.1038/Ni1209X  0.76
2005 Osborne BA, Kee BL. Lymphoid development: it's not 'all Greek to us' any more. Nature Immunology. 6: 119-23. PMID 15662436 DOI: 10.1038/Ni0205-119  0.322
2004 Laws AM, Osborne BA. p53 regulates thymic Notch1 activation. European Journal of Immunology. 34: 726-34. PMID 14991602 DOI: 10.1002/Eji.200324772  0.797
2003 Minter LM, Osborne BA. Cell death in the thymus--it' s all a matter of contacts. Seminars in Immunology. 15: 135-44. PMID 14563112 DOI: 10.1016/S1044-5323(03)00029-0  0.49
2003 Nickoloff BJ, Osborne BA, Miele L. Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents. Oncogene. 22: 6598-608. PMID 14528285 DOI: 10.1038/Sj.Onc.1206758  0.379
2003 Benson RM, Minter LM, Osborne BA, Granowitz EV. Hyperbaric oxygen inhibits stimulus-induced proinflammatory cytokine synthesis by human blood-derived monocyte-macrophages. Clinical and Experimental Immunology. 134: 57-62. PMID 12974755 DOI: 10.1046/J.1365-2249.2003.02248.X  0.309
2003 Palaga T, Miele L, Golde TE, Osborne BA. TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 3019-24. PMID 12960327 DOI: 10.4049/Jimmunol.171.6.3019  0.732
2003 Cheng P, Nefedova Y, Miele L, Osborne BA, Gabrilovich D. Notch signaling is necessary but not sufficient for differentiation of dendritic cells. Blood. 102: 3980-8. PMID 12907456 DOI: 10.1182/Blood-2003-04-1034  0.408
2003 Tonomura N, McLaughlin K, Grimm L, Goldsby RA, Osborne BA. Glucocorticoid-induced apoptosis of thymocytes: requirement of proteasome-dependent mitochondrial activity. Journal of Immunology (Baltimore, Md. : 1950). 170: 2469-78. PMID 12594272 DOI: 10.4049/Jimmunol.170.5.2469  0.777
2002 Ganguly BJ, Tonomura N, Benson RM, Osborne BA, Granowitz EV. Hyperbaric oxygen enhances apoptosis in hematopoietic cells. Apoptosis : An International Journal On Programmed Cell Death. 7: 499-510. PMID 12370492  0.759
2002 Lee JM, Lee KH, Weidner M, Osborne BA, Hayward SD. Epstein-Barr virus EBNA2 blocks Nur77- mediated apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 99: 11878-83. PMID 12195020 DOI: 10.1073/Pnas.182552499  0.422
2002 Weijzen S, Rizzo P, Braid M, Vaishnav R, Jonkheer SM, Zlobin A, Osborne BA, Gottipati S, Aster JC, Hahn WC, Rudolf M, Siziopikou K, Kast WM, Miele L. Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. Nature Medicine. 8: 979-86. PMID 12185362 DOI: 10.1038/Nm754  0.771
2002 Palaga T, Osborne B. The 3D's of apoptosis: death, degradation and DIAPs. Nature Cell Biology. 4: E149-51. PMID 12042828 DOI: 10.1038/Ncb0602-E149  0.59
2001 Cheng P, Zlobin A, Volgina V, Gottipati S, Osborne B, Simel EJ, Miele L, Gabrilovichz DI. Notch-1 regulates NF-κB activity in hemopoietic progenitor cells Journal of Immunology. 167: 4458-4467. PMID 11591772 DOI: 10.4049/Jimmunol.167.8.4458  0.793
2001 Valavanis C, Hu Y, Yang Y, Osborne BA, Chouaib S, Greene L, Ashwell JD, Schwartz LM. Model cell lines for the study of apoptosis in vitro. Methods in Cell Biology. 66: 417-36. PMID 11396014 DOI: 10.1016/S0091-679X(01)66019-9  0.442
2000 Osborne BA. Transcriptional control of T cell development. Current Opinion in Immunology. 12: 301-6. PMID 10781405 DOI: 10.1016/S0952-7915(00)00091-1  0.472
2000 Lockshin RA, Osborne B, Zakeri Z. Cell death in the third millennium Cell Death and Differentiation. 7: 2-7. PMID 10713714 DOI: 10.1038/Sj.Cdd.4400649  0.383
1999 Miele L, Osborne B. Arbiter of differentiation and death: Notch signaling meets apoptosis Journal of Cellular Physiology. 181: 393-409. PMID 10528225 DOI: 10.1002/(Sici)1097-4652(199912)181:3<393::Aid-Jcp3>3.0.Co;2-6  0.456
1999 Morgan G, Smith S, Pak J, Marshak-Rothstein A, Fissore R, Osborne B. Characterization of a mutant T-cell hybridoma line with defects in the TCR-mediated apoptotic pathway Cell Death and Differentiation. 6: 36-47. PMID 10200546 DOI: 10.1038/Sj.Cdd.4400447  0.448
1999 Grimm LM, Osborne BA. Apoptosis and the proteasome Results and Problems in Cell Differentiation. 23: 209-228. PMID 9950035 DOI: 10.1007/978-3-540-69184-6_10  0.382
1999 Amsen D, Revilla Calvo C, Osborne BA, Kruisbeek AM. Costimulatory signals are required for induction of transcription factor Nur77 during negative selection of CD4(+)CD8(+) thymocytes. Proceedings of the National Academy of Sciences of the United States of America. 96: 622-7. PMID 9892683 DOI: 10.1073/Pnas.96.2.622  0.454
1997 Osborne BA. Cell death in vertebrates: lessons from the worm. Trends in Genetics : Tig. 12: 489-91. PMID 9257523 DOI: 10.1016/S0168-9525(96)30108-X  0.342
1997 Jehn BM, Osborne BA. Gene regulation associated with apoptosis. Critical Reviews in Eukaryotic Gene Expression. 7: 179-93. PMID 9034721 DOI: 10.1615/Critreveukargeneexpr.V7.I1-2.100  0.402
1997 Osborne BA. Apoptosis and the maintenance of homoeostasis in the immune system. Current Opinion in Immunology. 8: 245-54. PMID 8725948 DOI: 10.1016/S0952-7915(96)80063-X  0.502
1997 Osborne BA, Smith S, McLaughlin K, Grimm L, Morgan G, Goldsby RA. MOLECULAR PATHWAYS TO APOPTOSIS IN THE THYMUS Shock. 7: 114. DOI: 10.1097/00024382-199703001-00459  0.325
1996 Osborne BA, Smith SW, McLaughlin KA, Grimm L, Morgan G, Goldsby RA. Genetic regulation of apoptosis in the mouse thymus Advances in Experimental Medicine and Biology. 406: 199-207. PMID 8910686 DOI: 10.1007/978-1-4899-0072-2_14  0.489
1996 Osborne BA, Smith SW, McLaughlin KA, Grimm L, Kallinch T, Liu Z, Schwartz LM. Genes that regulate apoptosis in the mouse thymus. Journal of Cellular Biochemistry. 60: 18-22. PMID 8825411 DOI: 10.1002/(Sici)1097-4644(19960101)60:1<18::Aid-Jcb4>3.0.Co;2-6  0.48
1996 McLaughlin KA, Osborne BA, Goldsby RA. The role of oxygen in thymocyte apoptosis European Journal of Immunology. 26: 1170-1174. PMID 8647183 DOI: 10.1002/Eji.1830260531  0.441
1996 Grimm LM, Goldberg AL, Poirier GG, Schwartz LM, Osborne BA. Proteasomes play an essential role in thymocyte apoptosis. The Embo Journal. 15: 3835-3844. DOI: 10.1002/J.1460-2075.1996.Tb00757.X  0.422
1995 Smith SW, McLaughlin KA, Osborne BA. Molecular events in thymocyte apoptosis Current Topics in Microbiology and Immunology. 200: 147-162. PMID 7634829 DOI: 10.1007/978-3-642-79437-7_11  0.486
1995 Osborne BA, Schwartz LM. Cell death suffers a TKO. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 17: 557-9. PMID 7575499 DOI: 10.1002/Bies.950170614  0.425
1995 Osborne BA. Induction of genes during apoptosis: examples from the immune system. Seminars in Cancer Biology. 6: 27-33. PMID 7548838 DOI: 10.1006/Scbi.1995.0004  0.414
1995 Osborne BA, Smith SW, Liu ZG, McLaughlin KA, Schwartz LM. Transient transfection assays to examine the requirement of putative cell death genes. Methods in Cell Biology. 46: 99-106. PMID 7541887 DOI: 10.1016/S0091-679X(08)61926-3  0.338
1994 Osborne BA, Schwartz LM. Essential genes that regulate apoptosis. Trends in Cell Biology. 4: 394-9. PMID 14731815 DOI: 10.1016/0962-8924(94)90052-3  0.332
1994 Punt JA, Osborne BA, Takahama Y, Sharrow SO, Singer A. Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28. The Journal of Experimental Medicine. 179: 709-13. PMID 8294878 DOI: 10.1084/Jem.179.2.709  0.389
1994 Ravichandran KS, Osborne BA, Goldsby RA. Quantitative analysis of the B cell repertoire by limiting dilution analysis and fluorescent in situ hybridization. Cellular Immunology. 154: 309-27. PMID 8131205 DOI: 10.1006/Cimm.1994.1080  0.345
1994 Liu ZG, Smith SW, McLaughlin KA, Schwartz LM, Osborne BA. Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77. Nature. 367: 281-4. PMID 8121494 DOI: 10.1038/367281A0  0.544
1994 Schwartz LM, Osborne BA. Ced-3/ICE: evolutionarily conserved regulation of cell death. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 16: 387-9. PMID 8080427 DOI: 10.1002/Bies.950160604  0.316
1994 Osborne BA, Smith SW, Liu ZG, McLaughlin KA, Grimm L, Schwartz LM. Identification of genes induced during apoptosis in T lymphocytes. Immunological Reviews. 142: 301-20. PMID 7698798 DOI: 10.1111/J.1600-065X.1994.Tb00894.X  0.419
1993 Lowe SW, Schmitt EM, Smith SW, Osborne BA, Jacks T. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature. 362: 847-9. PMID 8479522 DOI: 10.1038/362847A0  0.433
1993 Schwartz LM, Smith SW, Jones ME, Osborne BA. Do all programmed cell deaths occur via apoptosis? Proceedings of the National Academy of Sciences of the United States of America. 90: 980-4. PMID 8430112 DOI: 10.1073/Pnas.90.3.980  0.408
1993 Schwartz LM, Osborne BA. Programmed cell death, apoptosis and killer genes. Immunology Today. 14: 582-90. PMID 8305131 DOI: 10.1016/0167-5699(93)90197-S  0.327
1992 Ravichandran KS, Semproni AR, Goldsby RA, Osborne BA. Immunoglobulin VH usage analysis by fluorescent in situ hybridization and flow cytometry. Journal of Immunological Methods. 153: 249-59. PMID 1517596 DOI: 10.1016/0022-1759(92)90328-Q  0.342
1990 Ferguson SE, Cancro MP, Osborne BA. Analysis of a novel VHS107 haplotype in CLA-2 and WSA mice. Evidence for gene conversion among IgVH genes in outbred populations. The Journal of Experimental Medicine. 170: 1811-23. PMID 2584925 DOI: 10.1084/Jem.170.6.1811  0.651
1982 Singer DS, Camerini-Otero RD, Satz ML, Osborne B, Sachs D, Rudikoff S. Characterization of a porcine genomic clone encoding a major histocompatibility antigen: expression in mouse L cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 1403-1407. PMID 6461859 DOI: 10.1073/Pnas.79.5.1403  0.312
1980 Engleman EG, Benike C, Osborne B, Goldsby R. Functional characteristics of human T-cell subpopulations distinguished by a monoclonal antibody. Proceedings of the National Academy of Sciences of the United States of America. 77: 1607-11. PMID 6445560 DOI: 10.1073/Pnas.77.3.1607  0.458
1979 Goldsby RA, Osborne BA, Engleman EG. Identification, isolation, and characterization of a human T cell population by a monoclonal antibody Current Microbiology. 3: 141-146. DOI: 10.1007/Bf02601856  0.402
1978 Osborne BA, Goldsby RA, Herzenberg LA. Selective expression of loci in th I--J region on T cell hybrids. Current Topics in Microbiology and Immunology. 81: 217-20. PMID 80306 DOI: 10.1007/978-3-642-67448-8_35  0.452
1977 Herzenberg LA, Herzenberg LA, Black SJ, Loken MR, Okumura K, van der Loo W, Osborne BA, Hewgill D, Goding JW, Gutman G, Warner NL. Surface markers and functional relationships of cells involved in murine B-lymphocyte differentiation. Cold Spring Harbor Symposia On Quantitative Biology. 41: 33-45. PMID 408094 DOI: 10.1101/Sqb.1977.041.01.007  0.324
1977 Goldsby RA, Osborne BA, Simpson E, Herzenberg LA. Hybrid cell lines with T-cell characteristics. Nature. 267: 707-708. PMID 301614 DOI: 10.1038/267707A0  0.404
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