| Year |
Citation |
Score |
| 2024 |
Hofmann C, Aghajani M, D Alcock C, Blackwood EA, Sandmann C, Herzog N, Groß J, Plate L, Wiseman RL, Kaufman RJ, Katus HA, Jakobi T, Völkers M, Glembotski CC, Doroudgar S. ATF6 protects against protein misfolding during cardiac hypertrophy. Journal of Molecular and Cellular Cardiology. 189: 12-24. PMID 38401179 DOI: 10.1016/j.yjmcc.2024.02.001 |
0.457 |
|
| 2023 |
Glembotski CC, Bagchi S, Blackwood EA. ER-Specific Autophagy or ER-Phagy in Cardiac Myocytes Protects the Heart Against Doxorubicin-Induced Cardiotoxicity. Jacc. Cardiooncology. 5: 671-673. PMID 37969647 DOI: 10.1016/j.jaccao.2023.08.004 |
0.422 |
|
| 2023 |
Hofmann C, Löwenthal Z, Aghajani M, Kaufman RJ, Katus HA, Frey N, Glembotski CC, Völkers M, Doroudgar S. mTORC1 inhibition impairs activation of the unfolded protein response and induces cell death during ER stress in cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. PMID 37294892 DOI: 10.1152/ajpheart.00682.2022 |
0.766 |
|
| 2022 |
Blackwood EA, MacDonnell LF, Thuerauf DJ, Bilal AS, Murray VB, Bedi KC, Margulies KB, Glembotski CC. Noncanonical Form of ERAD Regulates Cardiac Hypertrophy. Circulation. PMID 36317534 DOI: 10.1161/CIRCULATIONAHA.122.061557 |
0.428 |
|
| 2021 |
Marsh KG, Arrieta A, Thuerauf DJ, Blackwood EA, MacDonnell L, Glembotski CC. The peroxisomal enzyme, FAR1, is induced during ER stress in an ATF6-dependent manner in cardiac myocytes. American Journal of Physiology. Heart and Circulatory Physiology. PMID 33666503 DOI: 10.1152/ajpheart.00999.2020 |
0.446 |
|
| 2020 |
Blackwood EA, Bilal AS, Azizi K, Sarakki A, Glembotski CC. Simultaneous Isolation and Culture of Atrial Myocytes, Ventricular Myocytes, and Non-Myocytes from an Adult Mouse Heart. Journal of Visualized Experiments : Jove. PMID 32597844 DOI: 10.3791/61224 |
0.387 |
|
| 2020 |
Blackwood EA, Thuerauf DJ, Stastna M, Stephens H, Sand Z, Pentoney A, Azizi K, Jakobi T, Van Eyk JE, Katus HA, Glembotski CC, Doroudgar S. Proteomic analysis of the cardiac myocyte secretome reveals extracellular protective functions for the ER stress response. Journal of Molecular and Cellular Cardiology. PMID 32339566 DOI: 10.1016/J.Yjmcc.2020.04.012 |
0.792 |
|
| 2020 |
Arrieta A, Blackwood EA, Stauffer WT, Domingo MS, Bilal AS, Thuerauf DJ, Pentoney AN, Aivati C, Sarakki AV, Doroudgar S, Glembotski CC. Mesencephalic astrocyte-derived neurotrophic factor is an ER-resident chaperone that protects against reductive stress in the heart. The Journal of Biological Chemistry. PMID 32327487 DOI: 10.1074/Jbc.Ra120.013345 |
0.797 |
|
| 2020 |
Glembotski CC, Arrieta A, Blackwood EA, Stauffer WT. ATF6 as a Nodal Regulator of Proteostasis in the Heart. Frontiers in Physiology. 11: 267. PMID 32322217 DOI: 10.3389/Fphys.2020.00267 |
0.574 |
|
| 2020 |
Palmer JE, Brietske BM, Bate TC, Blackwood EA, Garg M, Glembotski CC, Cooley CB. Reactive Oxygen Species (ROS)-Activatable Prodrug for Selective Activation of ATF6 after Ischemia/Reperfusion Injury. Acs Medicinal Chemistry Letters. 11: 292-297. PMID 32184959 DOI: 10.1021/Acsmedchemlett.9B00299 |
0.362 |
|
| 2020 |
Blackwood EA, Bilal AS, Stauffer WT, Arrieta A, Glembotski CC. Designing Novel Therapies to Mend Broken Hearts: ATF6 and Cardiac Proteostasis. Cells. 9. PMID 32138230 DOI: 10.3390/Cells9030602 |
0.572 |
|
| 2020 |
Stauffer WT, Blackwood EA, Azizi K, Kaufman RJ, Glembotski CC. The ER Unfolded Protein Response Effector, ATF6, Reduces Cardiac Fibrosis and Decreases Activation of Cardiac Fibroblasts. International Journal of Molecular Sciences. 21. PMID 32085622 DOI: 10.3390/Ijms21041373 |
0.526 |
|
| 2020 |
Stauffer WT, Arrieta A, Blackwood EA, Glembotski CC. Sledgehammer to Scalpel: Broad Challenges to the Heart and Other Tissues Yield Specific Cellular Responses via Transcriptional Regulation of the ER-Stress Master Regulator ATF6α. International Journal of Molecular Sciences. 21. PMID 32046286 DOI: 10.3390/Ijms21031134 |
0.528 |
|
| 2020 |
Cheung TKD, Bilal AS, Blackwood EA, Thuerauf DJ, Glembotski CC. ATF6β is an Adaptive Transcription Factor in Cardiac Myocyte. The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09606 |
0.372 |
|
| 2019 |
Arrieta A, Blackwood EA, Stauffer WT, Glembotski CC. Integrating ER and Mitochondrial Proteostasis in the Healthy and Diseased Heart. Frontiers in Cardiovascular Medicine. 6: 193. PMID 32010709 DOI: 10.3389/Fcvm.2019.00193 |
0.509 |
|
| 2019 |
Glembotski CC, Rosarda JD, Wiseman RL. Proteostasis and Beyond: ATF6 in Ischemic Disease. Trends in Molecular Medicine. PMID 31078432 DOI: 10.1016/J.Molmed.2019.03.005 |
0.45 |
|
| 2019 |
Glembotski CC, Arrieta A, Blackwood EA. Unfolding the Roles of Mitochondria as Therapeutic Targets for Heart Disease. Journal of the American College of Cardiology. 73: 1807-1810. PMID 30975298 DOI: 10.1016/J.Jacc.2018.12.089 |
0.357 |
|
| 2019 |
Blackwood EA, Azizi K, Thuerauf DJ, Paxman RJ, Plate L, Kelly JW, Wiseman RL, Glembotski CC. Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis. Nature Communications. 10: 187. PMID 30643122 DOI: 10.1016/J.Yjmcc.2018.07.047 |
0.492 |
|
| 2019 |
Blackwood EA, Hofmann C, Santo Domingo M, Bilal AS, Sarakki A, Stauffer W, Arrieta A, Thuerauf DJ, Kolkhorst FW, Müller OJ, Jakobi T, Dieterich C, Katus HA, Doroudgar S, Glembotski CC. ATF6 Regulates Cardiac Hypertrophy by Transcriptional Induction of the mTORC1 Activator, Rheb. Circulation Research. 124: 79-93. PMID 30582446 DOI: 10.1161/Circresaha.118.313854 |
0.788 |
|
| 2019 |
Stauffer WT, Blackwood EA, Azizi K, Stephens HN, Doroudgar S, Glembotski CC. Abstract 260: The ER Unfolded Protein Response Effector, ATF6, Reduces Fibrosis and Moderates Activation of Cardiac Fibroblasts Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.260 |
0.77 |
|
| 2018 |
Blackwood EA, Azizi K, Thuerauf DJ, Paxman RJ, Plate L, Kelly JW, Wiseman RL, Glembotski CC. Abstract 547: Pharmacologic ATF6 Activation Confers Global Protection in Widespread Disease Models by Reprogramming Cellular Proteostasis Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.547 |
0.306 |
|
| 2018 |
Stauffer WT, Doroudgar S, Stephens HN, Blackwood EA, Glembotski CC. Abstract 479: The ER Unfolded Protein Response Effector, ATF6, Promotes Proliferation and Maintains Pluripotency in Cardiac Stem Cells Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.479 |
0.744 |
|
| 2018 |
Arrieta A, Blackwood EA, Aivati C, Stauffer WT, Santo Domingo M, Bilal AS, Sarakki AV, Thuerauf DJ, Doroudgar S, Glembotski CC. Abstract 352: Manf, a Structurally Unique Redox-sensitive Chaperone, Restores Er-protein Folding in the Ischemic Heart Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.352 |
0.771 |
|
| 2017 |
Arrieta A, Blackwood EA, Glembotski CC. ER Protein Quality Control and the Unfolded Protein Response in the Heart. Current Topics in Microbiology and Immunology. PMID 29026925 DOI: 10.1007/82_2017_54 |
0.541 |
|
| 2017 |
Sacchi V, Wang BJ, Kubli D, Martinez AS, Jin JK, Alvarez R, Hariharan N, Glembotski C, Uchida T, Malter JS, Yang Y, Gross P, Zhang C, Houser S, Rota M, et al. Peptidyl-Prolyl Isomerase 1 Regulates Ca(2+) Handling by Modulating Sarco(Endo)Plasmic Reticulum Calcium ATPase and Na(2+)/Ca(2+) Exchanger 1 Protein Levels and Function. Journal of the American Heart Association. 6. PMID 29018025 DOI: 10.1161/Jaha.117.006837 |
0.382 |
|
| 2017 |
Glembotski CC. Expanding the Paracrine Hypothesis of Stem Cell-Mediated Repair in the Heart: When the Unconventional Becomes Conventional. Circulation Research. 120: 772-774. PMID 28254800 DOI: 10.1161/Circresaha.116.310298 |
0.337 |
|
| 2017 |
Gray CB, Suetomi T, Xiang S, Blackwood EA, Glembotski CC, Miyamoto S, Daan Westenbrink B, Brown JH. CaMKIIδ subtypes differentially regulate infarct formation following ex vivo myocardial ischemia/reperfusion through NF-κB and TNF-α. Journal of Molecular and Cellular Cardiology. PMID 28077321 DOI: 10.1016/J.Yjmcc.2017.01.002 |
0.418 |
|
| 2017 |
Arrieta A, Blackwood E, Stauffer WT, Domingo MS, Pentoney AN, Thuerauf DJ, Doroudgar S, Glembotski CC. MANF, a structurally unique redox-sensitive chaperone, restores ER-protein folding in the ischemic heart Journal of Molecular and Cellular Cardiology. 112: 165. DOI: 10.1016/J.Yjmcc.2017.07.102 |
0.76 |
|
| 2016 |
Jin JK, Blackwood EA, Azizi KM, Thuerauf DJ, Fahem AG, Hofmann C, Kaufman RJ, Doroudgar S, Glembotski CC. ATF6 Decreases Myocardial Ischemia/Reperfusion Damage and Links ER Stress and Oxidative Stress Signaling Pathways in the Heart. Circulation Research. PMID 27932512 DOI: 10.1161/Circresaha.116.310266 |
0.779 |
|
| 2016 |
Reynolds JO, Quick AP, Wang Q, Beavers DL, Philippen LE, Showell J, Barreto-Torres G, Thuerauf DJ, Doroudgar S, Glembotski CC, Wehrens XH. Junctophilin-2 gene therapy rescues heart failure by normalizing RyR2-mediated Ca(2+) release. International Journal of Cardiology. 225: 371-380. PMID 27760414 DOI: 10.1016/J.Ijcard.2016.10.021 |
0.709 |
|
| 2016 |
Doroudgar S, Quijada P, Konstandin M, Ilves K, Broughton K, Khalafalla FG, Casillas A, Nguyen K, Gude N, Toko H, Ornelas L, Thuerauf DJ, Glembotski CC, Sussman MA, Völkers M. S100A4 protects the myocardium against ischemic stress. Journal of Molecular and Cellular Cardiology. PMID 27721024 DOI: 10.1016/J.Yjmcc.2016.10.001 |
0.729 |
|
| 2016 |
Yu Z, Sheng H, Liu S, Zhao S, Glembotski CC, Warner DS, Paschen W, Yang W. Activation of the ATF6 branch of the unfolded protein response in neurons improves stroke outcome. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 27217380 DOI: 10.1177/0271678X16650218 |
0.406 |
|
| 2015 |
Glembotski CC. Breaking down the COP9 Signalsome in the heart: how inactivating a protein ubiquitin ligase increases protein ubiquitylation and protects the heart. Circulation Research. 117: 914-6. PMID 26541679 DOI: 10.1161/Circresaha.115.307644 |
0.481 |
|
| 2015 |
Doroudgar S, Völkers M, Thuerauf DJ, Khan M, Mohsin S, Respress JL, Wang W, Gude N, Müller OJ, Wehrens XH, Sussman MA, Glembotski CC. Hrd1 and ER-Associated Protein Degradation, ERAD, Are Critical Elements of the Adaptive ER Stress Response in Cardiac Myocytes. Circulation Research. 117: 536-46. PMID 26137860 DOI: 10.1161/Circresaha.115.306993 |
0.79 |
|
| 2014 |
Glembotski CC. Finding the missing link between the unfolded protein response and O-GlcNAcylation in the heart. Circulation Research. 115: 546-8. PMID 25170091 DOI: 10.1161/Circresaha.114.304855 |
0.524 |
|
| 2014 |
Völkers M, Doroudgar S, Nguyen N, Konstandin MH, Quijada P, Din S, Ornelas L, Thuerauf DJ, Gude N, Friedrich K, Herzig S, Glembotski CC, Sussman MA. PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity. Embo Molecular Medicine. 6: 57-65. PMID 24408966 DOI: 10.1002/Emmm.201303183 |
0.656 |
|
| 2014 |
Glembotski CC. Roles for ATF6 and the sarco/endoplasmic reticulum protein quality control system in the heart. Journal of Molecular and Cellular Cardiology. 71: 11-5. PMID 24140798 DOI: 10.1016/J.Yjmcc.2013.09.018 |
0.528 |
|
| 2013 |
Glembotski CC. Classic studies of cultured cardiac myocyte hypertrophy: interview with a transformer. Circulation Research. 113: 1112-6. PMID 24158575 DOI: 10.1161/Circresaha.113.302490 |
0.406 |
|
| 2013 |
Völkers M, Konstandin MH, Doroudgar S, Toko H, Quijada P, Din S, Joyo A, Ornelas L, Samse K, Thuerauf DJ, Gude N, Glembotski CC, Sussman MA. Mechanistic target of rapamycin complex 2 protects the heart from ischemic damage. Circulation. 128: 2132-44. PMID 24008870 DOI: 10.1161/Circulationaha.113.003638 |
0.698 |
|
| 2013 |
Völkers M, Toko H, Doroudgar S, Din S, Quijada P, Joyo AY, Ornelas L, Joyo E, Thuerauf DJ, Konstandin MH, Gude N, Glembotski CC, Sussman MA. Pathological hypertrophy amelioration by PRAS40-mediated inhibition of mTORC1. Proceedings of the National Academy of Sciences of the United States of America. 110: 12661-6. PMID 23842089 DOI: 10.1073/Pnas.1301455110 |
0.73 |
|
| 2013 |
Toko H, Konstandin MH, Doroudgar S, Ormachea L, Joyo E, Joyo AY, Din S, Gude NA, Collins B, Völkers M, Thuerauf DJ, Glembotski CC, Chen CH, Lu KP, Müller OJ, et al. Regulation of cardiac hypertrophic signaling by prolyl isomerase Pin1. Circulation Research. 112: 1244-52. PMID 23487407 DOI: 10.1161/Circresaha.113.301084 |
0.731 |
|
| 2013 |
Doroudgar S, Glembotski CC. ATF6 [corrected] and thrombospondin 4: the dynamic duo of the adaptive endoplasmic reticulum stress response. Circulation Research. 112: 9-12. PMID 23287452 DOI: 10.1161/Circresaha.112.280560 |
0.793 |
|
| 2013 |
Doroudgar S, Glembotski CC. New concepts of endoplasmic reticulum function in the heart: programmed to conserve. Journal of Molecular and Cellular Cardiology. 55: 85-91. PMID 23085588 DOI: 10.1016/J.Yjmcc.2012.10.006 |
0.78 |
|
| 2012 |
Glembotski CC. Roles for the sarco-/endoplasmic reticulum in cardiac myocyte contraction, protein synthesis, and protein quality control. Physiology (Bethesda, Md.). 27: 343-50. PMID 23223628 DOI: 10.1152/Physiol.00034.2012 |
0.476 |
|
| 2012 |
Glembotski CC. Clarifying the cardiac proteasome paradox: protein quality control. Circulation Research. 111: 509-12. PMID 22904038 DOI: 10.1161/Circresaha.112.275917 |
0.481 |
|
| 2012 |
Eletto D, Maganty A, Eletto D, Dersh D, Makarewich C, Biswas C, Paton JC, Paton AW, Doroudgar S, Glembotski CC, Argon Y. Limitation of individual folding resources in the ER leads to outcomes distinct from the unfolded protein response. Journal of Cell Science. 125: 4865-75. PMID 22854046 DOI: 10.1242/jcs.108928 |
0.75 |
|
| 2012 |
Glembotski CC, Thuerauf DJ, Huang C, Vekich JA, Gottlieb RA, Doroudgar S. Mesencephalic astrocyte-derived neurotrophic factor protects the heart from ischemic damage and is selectively secreted upon sarco/endoplasmic reticulum calcium depletion. The Journal of Biological Chemistry. 287: 25893-904. PMID 22637475 DOI: 10.1074/Jbc.M112.356345 |
0.758 |
|
| 2012 |
Vekich JA, Belmont PJ, Thuerauf DJ, Glembotski CC. Protein disulfide isomerase-associated 6 is an ATF6-inducible ER stress response protein that protects cardiac myocytes from ischemia/reperfusion-mediated cell death. Journal of Molecular and Cellular Cardiology. 53: 259-67. PMID 22609432 DOI: 10.1016/J.Yjmcc.2012.05.005 |
0.852 |
|
| 2012 |
Belmont PJ, Chen WJ, Thuerauf DJ, Glembotski CC. Regulation of microRNA expression in the heart by the ATF6 branch of the ER stress response. Journal of Molecular and Cellular Cardiology. 52: 1176-82. PMID 22326432 DOI: 10.1016/J.Yjmcc.2012.01.017 |
0.795 |
|
| 2012 |
Doroudgar S, Glembotski CC. Chapter 10 – Communication in the Heart: Cardiokines as Mediators of a Molecular Social Network Musclefundamental Biology and Mechanisms of Disease. 127-139. DOI: 10.1016/B978-0-12-381510-1.00010-7 |
0.661 |
|
| 2011 |
Doroudgar S, Glembotski CC. The cardiokine story unfolds: ischemic stress-induced protein secretion in the heart. Trends in Molecular Medicine. 17: 207-14. PMID 21277256 DOI: 10.1016/J.Molmed.2010.12.003 |
0.788 |
|
| 2011 |
Glembotski CC. Functions for the cardiomyokine, MANF, in cardioprotection, hypertrophy and heart failure. Journal of Molecular and Cellular Cardiology. 51: 512-7. PMID 20970425 DOI: 10.1016/J.Yjmcc.2010.10.008 |
0.51 |
|
| 2010 |
Borillo GA, Mason M, Quijada P, Völkers M, Cottage C, McGregor M, Din S, Fischer K, Gude N, Avitabile D, Barlow S, Alvarez R, Truffa S, Whittaker R, Glassy MS, ... ... Glembotski CC, et al. Pim-1 kinase protects mitochondrial integrity in cardiomyocytes. Circulation Research. 106: 1265-74. PMID 20203306 DOI: 10.1161/Circresaha.109.212035 |
0.33 |
|
| 2010 |
Belmont PJ, Chen WJ, San Pedro MN, Thuerauf DJ, Lowe NG, Gude N, Hilton B, Wolkowicz R, Sussman MA, Glembotski CC. Roles for endoplasmic reticulum-associated degradation and the novel endoplasmic reticulum stress response gene derlin-3 in the ischemic heart Circulation Research. 106: 307-316. PMID 19940266 DOI: 10.1161/Circresaha.109.203901 |
0.834 |
|
| 2009 |
Meex SJ, Weissglas-Volkov D, van der Kallen CJ, Thuerauf DJ, van Greevenbroek MM, Schalkwijk CG, Stehouwer CD, Feskens EJ, Heldens L, Ayoubi TA, Hofker MH, Wouters BG, Vlietinck R, Sinsheimer JS, Taskinen MR, ... ... Glembotski CC, et al. The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1322-7. PMID 19667116 DOI: 10.1161/Atvbaha.108.180240 |
0.341 |
|
| 2009 |
Doroudgar S, Thuerauf DJ, Marcinko MC, Belmont PJ, Glembotski CC. Ischemia activates the ATF6 branch of the endoplasmic reticulum stress response. The Journal of Biological Chemistry. 284: 29735-45. PMID 19622751 DOI: 10.1074/Jbc.M109.018036 |
0.81 |
|
| 2009 |
Whittaker R, Glassy MS, Gude N, Sussman MA, Gottlieb RA, Glembotski CC. Kinetics of the translocation and phosphorylation of alphaB-crystallin in mouse heart mitochondria during ex vivo ischemia. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1633-42. PMID 19252088 DOI: 10.1152/Ajpheart.01227.2008 |
0.398 |
|
| 2009 |
Yuan H, Perry CN, Huang C, Iwai-Kanai E, Carreira RS, Glembotski CC, Gottlieb RA. LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection. American Journal of Physiology. Heart and Circulatory Physiology. 296: H470-9. PMID 19098111 DOI: 10.1152/Ajpheart.01051.2008 |
0.346 |
|
| 2008 |
Tadimalla A, Belmont PJ, Thuerauf DJ, Glassy MS, Martindale JJ, Gude N, Sussman MA, Glembotski CC. Mesencephalic astrocyte-derived neurotrophic factor is an ischemia-inducible secreted endoplasmic reticulum stress response protein in the heart. Circulation Research. 103: 1249-58. PMID 18927462 DOI: 10.1161/Circresaha.108.180679 |
0.848 |
|
| 2008 |
Belmont PJ, Tadimalla A, Chen WJ, Martindale JJ, Thuerauf DJ, Marcinko M, Gude N, Sussman MA, Glembotski CC. Coordination of growth and endoplasmic reticulum stress signaling by regulator of calcineurin 1 (RCAN1), a novel ATF6-inducible gene. The Journal of Biological Chemistry. 283: 14012-21. PMID 18319259 DOI: 10.1074/Jbc.M709776200 |
0.829 |
|
| 2008 |
Glembotski CC. The role of the unfolded protein response in the heart. Journal of Molecular and Cellular Cardiology. 44: 453-9. PMID 18054039 DOI: 10.1016/J.Yjmcc.2007.10.017 |
0.584 |
|
| 2008 |
Jin JK, Whittaker R, Glassy MS, Barlow SB, Gottlieb RA, Glembotski CC. Localization of phosphorylated alphaB-crystallin to heart mitochondria during ischemia-reperfusion. American Journal of Physiology. Heart and Circulatory Physiology. 294: H337-44. PMID 17993600 DOI: 10.1152/Ajpheart.00881.2007 |
0.431 |
|
| 2007 |
Muraski JA, Rota M, Misao Y, Fransioli J, Cottage C, Gude N, Esposito G, Delucchi F, Arcarese M, Alvarez R, Siddiqi S, Emmanuel GN, Wu W, Fischer K, Martindale JJ, Glembotski CC, et al. Pim-1 regulates cardiomyocyte survival downstream of Akt Nature Medicine. 13: 1467-1475. PMID 18037896 DOI: 10.1038/Nm1671 |
0.414 |
|
| 2007 |
Glembotski CC. Endoplasmic reticulum stress in the heart. Circulation Research. 101: 975-84. PMID 17991891 DOI: 10.1161/Circresaha.107.161273 |
0.497 |
|
| 2007 |
Glembotski CC. Getting a G--RRP on regulated exocytosis in the heart. The Journal of Cell Biology. 179: 371-3. PMID 17967951 DOI: 10.1083/Jcb.200710021 |
0.403 |
|
| 2007 |
Thuerauf DJ, Marcinko M, Belmont PJ, Glembotski CC. Effects of the isoform-specific characteristics of ATF6 alpha and ATF6 beta on endoplasmic reticulum stress response gene expression and cell viability. The Journal of Biological Chemistry. 282: 22865-78. PMID 17522056 DOI: 10.1074/Jbc.M701213200 |
0.762 |
|
| 2006 |
Thuerauf DJ, Marcinko M, Gude N, Rubio M, Sussman MA, Glembotski CC. Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes. Circulation Research. 99: 275-82. PMID 16794188 DOI: 10.1161/01.Res.0000233317.70421.03 |
0.609 |
|
| 2006 |
Wall JA, Wei J, Ly M, Belmont P, Martindale JJ, Tran D, Sun J, Chen WJ, Yu W, Oeller P, Briggs S, Gustafsson AB, Sayen MR, Gottlieb RA, Glembotski CC. Alterations in oxidative phosphorylation complex proteins in the hearts of transgenic mice that overexpress the p38 MAP kinase activator, MAP kinase kinase 6. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2462-72. PMID 16766635 DOI: 10.1152/Ajpheart.01311.2005 |
0.795 |
|
| 2006 |
Martindale JJ, Fernandez R, Thuerauf D, Whittaker R, Gude N, Sussman MA, Glembotski CC. Endoplasmic reticulum stress gene induction and protection from ischemia/reperfusion injury in the hearts of transgenic mice with a tamoxifen-regulated form of ATF6. Circulation Research. 98: 1186-93. PMID 16601230 DOI: 10.1161/01.Res.0000220643.65941.8D |
0.562 |
|
| 2005 |
Kato T, Muraski J, Chen Y, Tsujita Y, Wall J, Glembotski CC, Schaefer E, Beckerle M, Sussman MA. Atrial natriuretic peptide promotes cardiomyocyte survival by cGMP-dependent nuclear accumulation of zyxin and Akt. The Journal of Clinical Investigation. 115: 2716-30. PMID 16200208 DOI: 10.1172/Jci24280 |
0.389 |
|
| 2005 |
McMullen ME, Bryant PW, Glembotski CC, Vincent PA, Pumiglia KM. Activation of p38 has opposing effects on the proliferation and migration of endothelial cells. The Journal of Biological Chemistry. 280: 20995-1003. PMID 15790570 DOI: 10.1074/Jbc.M407060200 |
0.327 |
|
| 2005 |
Martindale JJ, Wall JA, Martinez-Longoria DM, Aryal P, Rockman HA, Guo Y, Bolli R, Glembotski CC. Overexpression of mitogen-activated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo. The Journal of Biological Chemistry. 280: 669-76. PMID 15492008 DOI: 10.1074/Jbc.M406690200 |
0.492 |
|
| 2004 |
Thuerauf DJ, Morrison L, Glembotski CC. Opposing roles for ATF6alpha and ATF6beta in endoplasmic reticulum stress response gene induction. The Journal of Biological Chemistry. 279: 21078-84. PMID 14973138 DOI: 10.1074/Jbc.M400713200 |
0.462 |
|
| 2004 |
Morrison LE, Whittaker RJ, Klepper RE, Wawrousek EF, Glembotski CC. Roles for alphaB-crystallin and HSPB2 in protecting the myocardium from ischemia-reperfusion-induced damage in a KO mouse model. American Journal of Physiology. Heart and Circulatory Physiology. 286: H847-55. PMID 14592939 DOI: 10.1152/Ajpheart.00715.2003 |
0.451 |
|
| 2003 |
Andrews C, Ho PD, Dillmann WH, Glembotski CC, McDonough PM. The MKK6-p38 MAPK pathway prolongs the cardiac contractile calcium transient, downregulates SERCA2, and activates NF-AT. Cardiovascular Research. 59: 46-56. PMID 12829175 DOI: 10.1016/S0008-6363(03)00329-8 |
0.38 |
|
| 2003 |
Degousee N, Martindale J, Stefanski E, Cieslak M, Lindsay TF, Fish JE, Marsden PA, Thuerauf DJ, Glembotski CC, Rubin BB. MAP kinase kinase 6-p38 MAP kinase signaling cascade regulates cyclooxygenase-2 expression in cardiac myocytes in vitro and in vivo. Circulation Research. 92: 757-64. PMID 12649265 DOI: 10.1161/01.Res.0000067929.01404.03 |
0.427 |
|
| 2003 |
O'Brien NW, Gellings NM, Guo M, Barlow SB, Glembotski CC, Sabbadini RA. Factor associated with neutral sphingomyelinase activation and its role in cardiac cell death. Circulation Research. 92: 589-91. PMID 12637370 DOI: 10.1161/01.Res.0000066290.29715.67 |
0.429 |
|
| 2003 |
Morrison LE, Hoover HE, Thuerauf DJ, Glembotski CC. Mimicking phosphorylation of alphaB-crystallin on serine-59 is necessary and sufficient to provide maximal protection of cardiac myocytes from apoptosis. Circulation Research. 92: 203-11. PMID 12574148 DOI: 10.1161/01.Res.0000052989.83995.A5 |
0.487 |
|
| 2003 |
Cavalli AL, O'Brien NW, Barlow SB, Betto R, Glembotski CC, Palade PT, Sabbadini RA. Expression and functional characterization of SCaMPER: a sphingolipid-modulated calcium channel of cardiomyocytes. American Journal of Physiology. Cell Physiology. 284: C780-90. PMID 12421694 DOI: 10.1152/Ajpcell.00382.2002 |
0.327 |
|
| 2002 |
Thuerauf DJ, Morrison LE, Hoover H, Glembotski CC. Coordination of ATF6-mediated transcription and ATF6 degradation by a domain that is shared with the viral transcription factor, VP16. The Journal of Biological Chemistry. 277: 20734-9. PMID 11909875 DOI: 10.1074/Jbc.M201749200 |
0.447 |
|
| 2002 |
Post GR, Swiderski C, Waldrop BA, Salty L, Glembotski CC, Wolthuis RM, Mochizuki N. Guanine nucleotide exchange factor-like factor (Rlf) induces gene expression and potentiates alpha 1-adrenergic receptor-induced transcriptional responses in neonatal rat ventricular myocytes. The Journal of Biological Chemistry. 277: 15286-92. PMID 11847222 DOI: 10.1074/jbc.M111844200 |
0.332 |
|
| 2001 |
Thuerauf DJ, Hoover H, Meller J, Hernandez J, Su L, Andrews C, Dillmann WH, McDonough PM, Glembotski CC. Sarco/endoplasmic reticulum calcium ATPase-2 expression is regulated by ATF6 during the endoplasmic reticulum stress response: intracellular signaling of calcium stress in a cardiac myocyte model system. The Journal of Biological Chemistry. 276: 48309-17. PMID 11595740 DOI: 10.1074/Jbc.M107146200 |
0.467 |
|
| 2001 |
Craig R, Wagner M, McCardle T, Craig AG, Glembotski CC. The cytoprotective effects of the glycoprotein 130 receptor-coupled cytokine, cardiotrophin-1, require activation of NF-kappa B. The Journal of Biological Chemistry. 276: 37621-9. PMID 11448959 DOI: 10.1074/Jbc.M103276200 |
0.381 |
|
| 2000 |
Nakajima N, Cavalli AL, Biral D, Glembotski CC, McDonough PM, Ho PD, Betto R, Sandoná D, Palade PT, Dettbarn CA, Klepper RE, Sabbadini RA. Expression and characterization of Edg-1 receptors in rat cardiomyocytes: calcium deregulation in response to sphingosine 1-phosphate. European Journal of Biochemistry / Febs. 267: 5679-86. PMID 10971577 DOI: 10.1046/J.1432-1327.2000.01656.X |
0.415 |
|
| 2000 |
Morissette MR, Sah VP, Glembotski CC, Brown JH. The Rho effector, PKN, regulates ANF gene transcription in cardiomyocytes through a serum response element. American Journal of Physiology. Heart and Circulatory Physiology. 278: H1769-74. PMID 10843871 DOI: 10.1152/Ajpheart.2000.278.6.H1769 |
0.363 |
|
| 2000 |
Hoover HE, Thuerauf DJ, Martindale JJ, Glembotski CC. alpha B-crystallin gene induction and phosphorylation by MKK6-activated p38. A potential role for alpha B-crystallin as a target of the p38 branch of the cardiac stress response. The Journal of Biological Chemistry. 275: 23825-33. PMID 10816593 DOI: 10.1074/Jbc.M003864200 |
0.451 |
|
| 2000 |
Craig R, Larkin A, Mingo AM, Thuerauf DJ, Andrews C, McDonough PM, Glembotski CC. p38 MAPK and NF-kappa B collaborate to induce interleukin-6 gene expression and release. Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model system. The Journal of Biological Chemistry. 275: 23814-24. PMID 10781614 DOI: 10.1074/Jbc.M909695199 |
0.349 |
|
| 1998 |
Ho PD, Zechner DK, He H, Dillmann WH, Glembotski CC, McDonough PM. The Raf-MEK-ERK cascade represents a common pathway for alteration of intracellular calcium by Ras and protein kinase C in cardiac myocytes. The Journal of Biological Chemistry. 273: 21730-5. PMID 9705309 DOI: 10.1074/Jbc.273.34.21730 |
0.348 |
|
| 1998 |
Thuerauf DJ, Arnold ND, Zechner D, Hanford DS, DeMartin KM, McDonough PM, Prywes R, Glembotski CC. p38 Mitogen-activated protein kinase mediates the transcriptional induction of the atrial natriuretic factor gene through a serum response element. A potential role for the transcription factor ATF6. The Journal of Biological Chemistry. 273: 20636-43. PMID 9685422 DOI: 10.1074/Jbc.273.32.20636 |
0.438 |
|
| 1998 |
Zechner D, Craig R, Hanford DS, McDonough PM, Sabbadini RA, Glembotski CC. MKK6 activates myocardial cell NF-kappaB and inhibits apoptosis in a p38 mitogen-activated protein kinase-dependent manner. The Journal of Biological Chemistry. 273: 8232-9. PMID 9525929 DOI: 10.1074/Jbc.273.14.8232 |
0.428 |
|
| 1997 |
Zechner D, Thuerauf DJ, Hanford DS, McDonough PM, Glembotski CC. A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression. The Journal of Cell Biology. 139: 115-27. PMID 9314533 DOI: 10.1083/Jcb.139.1.115 |
0.406 |
|
| 1997 |
McDonough PM, Hanford DS, Sprenkle AB, Mellon NR, Glembotski CC. Collaborative roles for c-Jun N-terminal kinase, c-Jun, serum response factor, and Sp1 in calcium-regulated myocardial gene expression. The Journal of Biological Chemistry. 272: 24046-53. PMID 9295358 DOI: 10.1074/Jbc.272.38.24046 |
0.362 |
|
| 1997 |
Thuerauf DJ, Glembotski CC. Differential effects of protein kinase C, Ras, and Raf-1 kinase on the induction of the cardiac B-type natriuretic peptide gene through a critical promoter-proximal M-CAT element. The Journal of Biological Chemistry. 272: 7464-72. PMID 9054448 DOI: 10.1074/Jbc.272.11.7464 |
0.38 |
|
| 1996 |
Krown KA, Page MT, Nguyen C, Zechner D, Gutierrez V, Comstock KL, Glembotski CC, Quintana PJ, Sabbadini RA. Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death. The Journal of Clinical Investigation. 98: 2854-65. PMID 8981934 DOI: 10.1172/Jci119114 |
0.414 |
|
| 1996 |
Hanford DS, Glembotski CC. Stabilization of the B-type natriuretic peptide mRNA in cardiac myocytes by alpha-adrenergic receptor activation: potential roles for protein kinase C and mitogen-activated protein kinase. Molecular Endocrinology (Baltimore, Md.). 10: 1719-27. PMID 8961280 DOI: 10.1210/Mend.10.12.8961280 |
0.373 |
|
| 1996 |
Post GR, Goldstein D, Thuerauf DJ, Glembotski CC, Brown JH. Dissociation of p44 and p42 mitogen-activated protein kinase activation from receptor-induced hypertrophy in neonatal rat ventricular myocytes. The Journal of Biological Chemistry. 271: 8452-7. PMID 8626545 DOI: 10.1074/Jbc.271.14.8452 |
0.443 |
|
| 1996 |
Wollert KC, Taga T, Saito M, Narazaki M, Kishimoto T, Glembotski CC, Vernallis AB, Heath JK, Pennica D, Wood WI, Chien KR. Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy. Assembly of sarcomeric units in series VIA gp130/leukemia inhibitory factor receptor-dependent pathways. The Journal of Biological Chemistry. 271: 9535-45. PMID 8621626 DOI: 10.1074/Jbc.271.16.9535 |
0.312 |
|
| 1995 |
Sprenkle AB, Murray SF, Glembotski CC. Involvement of multiple cis elements in basal- and alpha-adrenergic agonist-inducible atrial natriuretic factor transcription. Roles for serum response elements and an SP-1-like element. Circulation Research. 77: 1060-9. PMID 7586217 DOI: 10.1161/01.Res.77.6.1060 |
0.324 |
|
| 1993 |
Irons CE, Sei CA, Glembotski CC. Regulated secretion of atrial natriuretic factor from cultured ventricular myocytes. The American Journal of Physiology. 264: H282-5. PMID 8430857 DOI: 10.1152/Ajpheart.1993.264.1.H282 |
0.332 |
|
| 1992 |
Sei CA, Hand GL, Murray SF, Glembotski CC. The cosecretional maturation of atrial natriuretic factor by primary atrial myocytes. Molecular Endocrinology (Baltimore, Md.). 6: 309-19. PMID 1533896 DOI: 10.1210/Mend.6.3.1533896 |
0.361 |
|
| 1991 |
Glembotski CC, Irons CE, Sprenkle AB, Sei CA. Studies of ANF processing and secretion using a primary cardiocyte culture model. Canadian Journal of Physiology and Pharmacology. 69: 1525-36. PMID 1838022 DOI: 10.1139/Y91-228 |
0.347 |
|
| 1987 |
Shields PP, Glembotski CC. Characterization of the molecular forms of ANP released by perfused neonatal rat heart. Biochemical and Biophysical Research Communications. 146: 547-53. PMID 2956946 DOI: 10.1016/0006-291X(87)90563-8 |
0.308 |
|
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