Wayne R. Giles - Publications

Affiliations: 
1983-2003 Physiology and Biophysics University of Calgary, Calgary, Alberta, Canada 
 2003-2006 Bioengineering University of California, San Diego, La Jolla, CA 
 2006- Kinesiology University of Calgary, Calgary, Alberta, Canada 
Area:
Biomedical Engineering, Physiology Biology
Website:
https://contacts.ucalgary.ca/info/kn/profiles/196-1294

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Hu W, Clark RB, Giles WR, Kondo C, Zhang H. Frequency-Dependent Properties of the Hyperpolarization-Activated Cation Current, I, in Adult Mouse Heart Primary Pacemaker Myocytes. International Journal of Molecular Sciences. 23. PMID 35457119 DOI: 10.3390/ijms23084299  0.312
2021 Hu W, Clark RB, Giles WR, Shibata E, Zhang H. Physiological Roles of the Rapidly Activated Delayed Rectifier K Current in Adult Mouse Heart Primary Pacemaker Activity. International Journal of Molecular Sciences. 22. PMID 33946248 DOI: 10.3390/ijms22094761  0.357
2018 Maleckar MM, Clark RB, Votta B, Giles WR. The Resting Potential and K Currents in Primary Human Articular Chondrocytes. Frontiers in Physiology. 9: 974. PMID 30233381 DOI: 10.3389/Fphys.2018.00974  0.309
2017 Ni H, Whittaker DG, Wang W, Giles WR, Narayan SM, Zhang H. Synergistic Anti-arrhythmic Effects in Human Atria with Combined Use of Sodium Blockers and Acacetin. Frontiers in Physiology. 8: 946. PMID 29218016 DOI: 10.3389/Fphys.2017.00946  0.301
2017 Trenor B, Cardona K, Romero L, Gomez JF, Saiz J, Rajamani S, Belardinelli L, Giles W. Pro-arrhythmic effects of low plasma [K+] in human ventricle: An illustrated review. Trends in Cardiovascular Medicine. PMID 29203397 DOI: 10.1016/j.tcm.2017.11.002  0.307
2011 Clark RB, Kondo C, Belke DD, Giles WR. Two-pore domain K + channels regulate membrane potential of isolated human articular chondrocytes Journal of Physiology. 589: 5071-5089. PMID 21911614 DOI: 10.1113/jphysiol.2011.210757  0.309
2008 Landeen LK, Dederko DA, Kondo CS, Hu BS, Aroonsakool N, Haga JH, Giles WR. Mechanisms of the negative inotropic effects of sphingosine-1-phosphate on adult mouse ventricular myocytes. American Journal of Physiology. Heart and Circulatory Physiology. 294: H736-49. PMID 18024550 DOI: 10.1152/Ajpheart.00316.2007  0.639
2008 Fink M, Noble D, Virag L, Varro A, Giles WR. Contributions of HERG K+ current to repolarization of the human ventricular action potential. Progress in Biophysics and Molecular Biology. 96: 357-76. PMID 17919688 DOI: 10.1016/J.Pbiomolbio.2007.07.011  0.417
2007 Alaynick WA, Kondo RP, Xie W, He W, Dufour CR, Downes M, Jonker JW, Giles W, Naviaux RK, Giguère V, Evans RM. ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart. Cell Metabolism. 6: 13-24. PMID 17618853 DOI: 10.1016/J.Cmet.2007.06.007  0.3
2007 Chilton L, Giles WR, Smith GL. Evidence of intercellular coupling between co-cultured adult rabbit ventricular myocytes and myofibroblasts. The Journal of Physiology. 583: 225-36. PMID 17569734 DOI: 10.1113/Jphysiol.2007.135038  0.304
2007 Flaim SN, Giles WR, McCulloch AD. Arrhythmogenic consequences of Na+ channel mutations in the transmurally heterogeneous mammalian left ventricle: analysis of the I1768V SCN5A mutation. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 4: 768-78. PMID 17556201 DOI: 10.1016/J.Hrthm.2007.02.009  0.348
2007 Hu BS, Landeen LK, Aroonsakool N, Giles WR. An analysis of the effects of stretch on IGF-I secretion from rat ventricular fibroblasts. American Journal of Physiology. Heart and Circulatory Physiology. 293: H677-83. PMID 17400715 DOI: 10.1152/Ajpheart.01413.2006  0.59
2007 Ocorr K, Reeves NL, Wessells RJ, Fink M, Chen HS, Akasaka T, Yasuda S, Metzger JM, Giles W, Posakony JW, Bodmer R. KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging. Proceedings of the National Academy of Sciences of the United States of America. 104: 3943-8. PMID 17360457 DOI: 10.1073/Pnas.0609278104  0.385
2007 Landeen LK, Aroonsakool N, Haga JH, Hu BS, Giles WR. Sphingosine-1-phosphate receptor expression in cardiac fibroblasts is modulated by in vitro culture conditions. American Journal of Physiology. Heart and Circulatory Physiology. 292: H2698-711. PMID 17337593 DOI: 10.1152/Ajpheart.01065.2006  0.608
2007 MacCannell KA, Bazzazi H, Chilton L, Shibukawa Y, Clark RB, Giles WR. A mathematical model of electrotonic interactions between ventricular myocytes and fibroblasts Biophysical Journal. 92: 4121-4132. PMID 17307821 DOI: 10.1529/biophysj.106.101410  0.302
2007 Teutsch C, Kondo RP, Dederko DA, Chrast J, Chien KR, Giles WR. Spatial distributions of Kv4 channels and KChip2 isoforms in the murine heart based on laser capture microdissection. Cardiovascular Research. 73: 739-49. PMID 17289005 DOI: 10.1016/J.Cardiores.2006.11.034  0.361
2007 Luykenaar KD, Wu B, Brayden JE, Giles WR, Corteling RL, Wiehler WB, Welsh DG. Hyposmotic Challenge Inhibits Inward Rectifying K+ Channels in Cerebral Arterial Smooth Muscle Cells The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A520-D  0.302
2006 Flaim SN, Giles WR, McCulloch AD. Contributions of sustained INa and IKv43 to transmural heterogeneity of early repolarization and arrhythmogenesis in canine left ventricular myocytes. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2617-29. PMID 16829642 DOI: 10.1152/Ajpheart.00350.2006  0.307
2006 Dos Santos RW, Otaviano Campos F, Neumann Ciuffo L, Nygren A, Giles W, Koch H. ATX-II effects on the apparent location of M cells in a computational model of a human left ventricular wedge. Journal of Cardiovascular Electrophysiology. 17: S86-S95. PMID 16686688 DOI: 10.1111/J.1540-8167.2006.00389.X  0.337
2006 Bazzazi H, Clark RB, Giles WR. Mathematical Simulations of the Effects of Altered AMP-Kinase Activity on INa and the Action Potential in Rat Ventricle Journal of Cardiovascular Electrophysiology. 17. PMID 16686674 DOI: 10.1111/J.1540-8167.2006.00402.X  0.371
2006 Nygren A, Baczkó I, Giles WR. Measurements of Electrophysiological Effects of Components of Acute Ischemia in Langendorff-Perfused Rat Hearts Using Voltage-Sensitive Dye Mapping Journal of Cardiovascular Electrophysiology. 17. PMID 16686665 DOI: 10.1111/J.1540-8167.2006.00392.X  0.368
2006 Fink M, Giles WR, Noble D. Contributions of inwardly rectifying K+ currents to repolarization assessed using mathematical models of human ventricular myocytes. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 364: 1207-22. PMID 16608704 DOI: 10.1098/rsta.2006.1765  0.307
2006 Ochi R, Momose Y, Oyama K, Giles WR. Sphingosine-1-phosphate effects on guinea pig atrial myocytes: Alterations in action potentials and K+ currents Cardiovascular Research. 70: 88-96. PMID 16545787 DOI: 10.1016/J.Cardiores.2006.01.010  0.381
2006 Kondo RP, Dederko DA, Teutsch C, Chrast J, Catalucci D, Chien KR, Giles WR. Comparison of contraction and calcium handling between right and left ventricular myocytes from adult mouse heart: a role for repolarization waveform. The Journal of Physiology. 571: 131-46. PMID 16357014 DOI: 10.1113/Jphysiol.2005.101428  0.418
2006 Ward CA, Bazzazi H, Clark RB, Nygren A, Giles WR. Actions of emigrated neutrophils on Na(+) and K(+) currents in rat ventricular myocytes. Progress in Biophysics & Molecular Biology. 90: 249-269. PMID 16165196 DOI: 10.1016/J.Pbiomolbio.2005.07.003  0.456
2005 Giles WR. Supraventricular pacemaker activity in the canine heart: contributions from HCN channels in control conditions and in a model of heart failure. Cardiovascular Research. 66: 430-432. PMID 15914107 DOI: 10.1016/J.Cardiores.2005.04.001  0.326
2005 Baczkó I, Jones L, McGuigan CF, Manning Fox JE, Gandhi M, Giles WR, Clanachan AS, Light PE. Plasma membrane KATP channel-mediated cardioprotection involves posthypoxic reductions in calcium overload and contractile dysfunction: mechanistic insights into cardioplegia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 980-2. PMID 15774423 DOI: 10.1096/Fj.04-3008Fje  0.399
2005 Shibukawa Y, Chilton EL, MacCannell KA, Clark RB, Giles WR. K+ currents activated by depolarization in cardiac fibroblasts Biophysical Journal. 88: 3924-3935. PMID 15764658 DOI: 10.1529/Biophysj.104.054429  0.398
2005 Chilton L, Ohya S, Freed D, George E, Drobic V, Shibukawa Y, MacCannell KA, Imaizumi Y, Clark RB, Dixon IMC, Giles WR. K+ currents regulate the resting membrane potential, proliferation, and contractile responses in ventricular fibroblasts and myofibroblasts American Journal of Physiology - Heart and Circulatory Physiology. 288: H2931-H2939. PMID 15653752 DOI: 10.1152/Ajpheart.01220.2004  0.393
2004 Brouillette J, Clark RB, Giles WR, Fiset C. Functional properties of K + currents in adult mouse ventricular myocytes The Journal of Physiology. 559: 777-798. PMID 15272047 DOI: 10.1113/Jphysiol.2004.063446  0.421
2004 Pashmforoush M, Lu JT, Chen H, Amand TS, Kondo R, Pradervand S, Evans SM, Clark B, Feramisco JR, Giles W, Ho SY, Benson DW, Silberbach M, Shou W, Chien KR. Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block. Cell. 117: 373-86. PMID 15109497 DOI: 10.1016/S0092-8674(04)00405-2  0.35
2004 Baczkó I, Giles WR, Light PE. Pharmacological activation of plasma-membrane KATP channels reduces reoxygenation-induced Ca(2+) overload in cardiac myocytes via modulation of the diastolic membrane potential. British Journal of Pharmacology. 141: 1059-67. PMID 14993099 DOI: 10.1038/Sj.Bjp.0705702  0.386
2004 Bouchard R, Clark RB, Juhasz AE, Giles WR. Changes in extracellular K+ concentration modulate contractility of rat and rabbit cardiac myocytes via the inward rectifier K+ current IK1. The Journal of Physiology. 556: 773-90. PMID 14990678 DOI: 10.1113/Jphysiol.2003.058248  0.462
2003 Lomax AE, Rose RA, Giles WR. Electrophysiological evidence for a gradient of G protein-gated K+ current in adult mouse atria. British Journal of Pharmacology. 140: 576-84. PMID 14522844 DOI: 10.1038/Sj.Bjp.0705474  0.42
2003 Baczkó I, Giles WR, Light PE. Resting membrane potential regulates Na(+)-Ca2+ exchange-mediated Ca2+ overload during hypoxia-reoxygenation in rat ventricular myocytes. The Journal of Physiology. 550: 889-98. PMID 12807988 DOI: 10.1113/Jphysiol.2003.043372  0.38
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