Denis Noble - Publications

Affiliations: 
University of Oxford, Oxford, United Kingdom 

145 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Felin T, Koenderink J, Krueger JI, Noble D, Ellis GFR. The data-hypothesis relationship. Genome Biology. 22: 57. PMID 33568195 DOI: 10.1186/s13059-021-02276-4  0.558
2021 Felin T, Koenderink J, Krueger JI, Noble D, Ellis GFR. Data bias. Genome Biology. 22: 59. PMID 33568166 DOI: 10.1186/s13059-021-02278-2  0.563
2020 Noble D. The surprising heart revisited: an early history of the funny current with modern lessons. Progress in Biophysics and Molecular Biology. PMID 32861776 DOI: 10.1016/j.pbiomolbio.2020.07.010  0.332
2020 Ma YL, Hu RM, Yang X, Wang T, Noble PJ, Wilkins R, Ellory C, Carr C, Noble D, Yang J, Lu W, Zhang J, Hu H, Guo X, Chen M, et al. Investigation of the Cellular Pharmacological Mechanism and Clinical Evidence of the Multi-Herbal Antiarrhythmic Chinese Medicine Xin Su Ning. Frontiers in Pharmacology. 11: 600. PMID 32435196 DOI: 10.3389/Fphar.2020.00600  0.302
2020 Noble D, Hunter P. How to link genomics to physiology through epigenomics. Epigenomics. PMID 32081034 DOI: 10.2217/Epi-2020-0012  0.44
2020 Auffray C, Balling R, Blomberg N, Bonaldo MC, Boutron B, Brahmachari S, Bréchot C, Cesario A, Chen S, Clément K, Danilenko D, Di Meglio A, Gelemanović A, Goble C, Gojobori T, ... ... Noble D, et al. COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight F1000research. 9: 1130. DOI: 10.12688/F1000Research.26098.1  0.476
2019 Hunter P, Tawhai M, Noble D. A Tribute to Ewald Weibel. Physiology (Bethesda, Md.). 34: 164-166. PMID 30968754 DOI: 10.1152/Physiol.00007.2019  0.419
2017 Trenor B, Cardona K, Saiz J, Noble D, Giles W. Cardiac action potential repolarization re-visited: early repolarization shows all-or-none behaviour. The Journal of Physiology. PMID 28815597 DOI: 10.1113/JP273651  0.349
2017 Chater N, Felin T, Funder DC, Gigerenzer G, Koenderink JJ, Krueger JI, Noble D, Nordli SA, Oaksford M, Schwartz B, Stanovich KE, Todd PM. Mind, rationality, and cognition: An interdisciplinary debate. Psychonomic Bulletin & Review. PMID 28744767 DOI: 10.3758/S13423-017-1333-5  0.613
2016 Davies MR, Wang K, Mirams GR, Caruso A, Noble D, Walz A, Lavé T, Schuler F, Singer T, Polonchuk L. Recent developments in using mechanistic cardiac modelling for drug safety evaluation. Drug Discovery Today. PMID 26891981 DOI: 10.1016/j.drudis.2016.02.003  0.301
2016 Giles WR, Noble D. Rigorous Phenotyping of Cardiac iPSC Preparations Requires Knowledge of Their Resting Potential(s). Biophysical Journal. 110: 278-280. PMID 26745430 DOI: 10.1016/j.bpj.2015.06.070  0.34
2016 Davies M, Wang K, Caruso A, Mirams G, Noble D, Walz A, Lave T, Schuler F, Singer T, Polonchuk L. What are the challenges and opportunities ahead of any regulatory requirements for in silico cardiac pro-arrhythmia prediction? Journal of Pharmacological and Toxicological Methods. 81: 349. DOI: 10.1016/j.vascn.2016.02.048  0.31
2016 Wang K, Mirams G, Davies M, Caruso A, Noble D, Alvarez-Sanchez R, Christine Walz A, Lave T, Schuler F, Singer T, Polonchuk L. Simulation of L-Type Calcium Currents using Different Experimental Data Sources: from Cell Line to iPS-Derived Cardiomyocyte Biophysical Journal. 110: 450a. DOI: 10.1016/j.bpj.2015.11.2418  0.349
2015 Varghese A, Spindler AJ, Paterson DJ, Noble D. Rate Dependent Activation Failure in Isolated Cardiac Cells and Tissue due to Na Channel Block. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00805.2014. PMID 26342072 DOI: 10.1152/ajpheart.00805.2014  0.472
2015 Henney A, Hunter P, McCulloch A, Noble D. Multi-bio and multi-scale systems biology. Progress in Biophysics and Molecular Biology. 117: 1-3. PMID 25783046 DOI: 10.1016/J.Pbiomolbio.2015.03.001  0.567
2013 Sher AA, Wang K, Wathen A, Maybank PJ, Mirams GR, Abramson D, Noble D, Gavaghan DJ. A local sensitivity analysis method for developing biological models with identifiable parameters: Application to cardiac ionic channel modelling Future Generation Computer Systems. 29: 591-598. DOI: 10.1016/j.future.2011.09.006  0.324
2012 Mirams GR, Davies MR, Cui Y, Kohl P, Noble D. Application of cardiac electrophysiology simulations to pro-arrhythmic safety testing. British Journal of Pharmacology. 167: 932-45. PMID 22568589 DOI: 10.1111/J.1476-5381.2012.02020.X  0.352
2012 Noble D, Garny A, Noble PJ. How the Hodgkin-Huxley equations inspired the Cardiac Physiome Project. The Journal of Physiology. 590: 2613-28. PMID 22473779 DOI: 10.1113/jphysiol.2011.224238  0.333
2012 Noble D, Kurachi Y, Hunter P, Wang X, Gordon M, Boron W. Physiology without borders 2. Physiology (Bethesda, Md.). 27: 2. PMID 22311965 DOI: 10.1152/Physiol.00045.2011  0.439
2012 DiFrancesco D, Noble D. Rebuttal: "The funny current in the context of the coupled clock pacemaker cell system". Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 457-8. PMID 21925135 DOI: 10.1016/j.hrthm.2011.09.023  0.315
2012 DiFrancesco D, Noble D. The funny current has a major pacemaking role in the sinus node. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 299-301. PMID 21925134 DOI: 10.1016/j.hrthm.2011.09.021  0.395
2012 Sher AA, Carter P, Bethwaite B, Noble D, Abramson D, Gavaghan DJ. Global Sensitivity Analysis of Arrhythmic Risk Biomarkers in Cardiac Single Cell Models Biophysical Journal. 102: 596a. DOI: 10.1016/j.bpj.2011.11.3247  0.325
2011 Mirams GR, Noble D. Is it time for in silico simulation of drug cardiac side effects? Annals of the New York Academy of Sciences. 1245: 44-7. PMID 22211977 DOI: 10.1111/j.1749-6632.2011.06324.x  0.301
2011 Quinn TA, Granite S, Allessie MA, Antzelevitch C, Bollensdorff C, Bub G, Burton RA, Cerbai E, Chen PS, Delmar M, Difrancesco D, Earm YE, Efimov IR, Egger M, Entcheva E, ... ... Noble D, et al. Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing. Progress in Biophysics and Molecular Biology. 107: 4-10. PMID 21745496 DOI: 10.1016/J.Pbiomolbio.2011.07.001  0.621
2011 Bousquet J, Anto JM, Sterk PJ, Adcock IM, Chung KF, Roca J, Agusti A, Brightling C, Cambon-Thomsen A, Cesario A, Abdelhak S, Antonarakis SE, Avignon A, Ballabio A, Baraldi E, ... ... Noble D, et al. Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Medicine. 3: 43. PMID 21745417 DOI: 10.1186/Gm259  0.466
2011 Cooper J, Corrias A, Gavaghan D, Noble D. Considerations for the use of cellular electrophysiology models within cardiac tissue simulations. Progress in Biophysics and Molecular Biology. 107: 74-80. PMID 21703295 DOI: 10.1016/j.pbiomolbio.2011.06.002  0.319
2011 Noble D. Successes and failures in modeling heart cell electrophysiology. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 8: 1798-803. PMID 21699872 DOI: 10.1016/j.hrthm.2011.06.014  0.309
2010 Noble D, Noble PJ, Fink M. Competing oscillators in cardiac pacemaking: historical background. Circulation Research. 106: 1791-7. PMID 20576941 DOI: 10.1161/CIRCRESAHA.110.218875  0.324
2010 Fink M, Noble D. Pharmacodynamic effects in the cardiovascular system: the modeller's view. Basic & Clinical Pharmacology & Toxicology. 106: 243-9. PMID 20470255 DOI: 10.1111/j.1742-7843.2009.00534.x  0.361
2010 Surovyatkina E, Noble D, Gavaghan D, Sher A. Multistability property in cardiac ionic models of mammalian and human ventricular cells. Progress in Biophysics and Molecular Biology. 103: 131-41. PMID 20153355 DOI: 10.1016/j.pbiomolbio.2010.01.004  0.355
2010 Noble D. Biophysics and systems biology. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 368: 1125-39. PMID 20123750 DOI: 10.1098/rsta.2009.0245  0.3
2009 Auffray C, Noble D. Origins of systems biology in William Harvey's masterpiece on the movement of the heart and the blood in animals. International Journal of Molecular Sciences. 10: 1658-69. PMID 19468331 DOI: 10.3390/ijms10041658  0.322
2009 Stewart P, Aslanidi OV, Noble D, Noble PJ, Boyett MR, Zhang H. Mathematical models of the electrical action potential of Purkinje fibre cells. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 367: 2225-55. PMID 19414454 DOI: 10.1098/Rsta.2008.0283  0.386
2009 Fink M, Noble D. Markov models for ion channels: versatility versus identifiability and speed. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 367: 2161-79. PMID 19414451 DOI: 10.1098/rsta.2008.0301  0.309
2009 Garny A, Noble D, Hunter PJ, Kohl P. CELLULAR OPEN RESOURCE (COR): current status and future directions. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 367: 1885-905. PMID 19380317 DOI: 10.1098/Rsta.2008.0289  0.49
2009 Niederer SA, Fink M, Noble D, Smith NP. A meta-analysis of cardiac electrophysiology computational models. Experimental Physiology. 94: 486-95. PMID 19139063 DOI: 10.1113/expphysiol.2008.044610  0.341
2009 Bassingthwaighte J, Hunter P, Noble D. The Cardiac Physiome: perspectives for the future. Experimental Physiology. 94: 597-605. PMID 19098089 DOI: 10.1113/Expphysiol.2008.044099  0.504
2008 Lei M, Grace AA, Huang CL, Noble D. Cardiac arrhythmogenesis is a major clinical problem. Progress in Biophysics and Molecular Biology. 98: 119. PMID 19351511 DOI: 10.1016/J.Pbiomolbio.2009.02.001  0.409
2008 Milberg P, Pott C, Fink M, Frommeyer G, Matsuda T, Baba A, Osada N, Breithardt G, Noble D, Eckardt L. Inhibition of the Na+/Ca2+ exchanger suppresses torsades de pointes in an intact heart model of long QT syndrome-2 and long QT syndrome-3. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 5: 1444-52. PMID 18929333 DOI: 10.1016/J.Hrthm.2008.06.017  0.342
2008 Hunter P, Kurachi Y, Noble D, Viceconti M. Meeting Report on the 2nd MEI International Symposium - The Worldwide Challenge to Physiome and Systems Biology and Osaka Accord -. The Journal of Physiological Sciences : Jps. 58: 425-31. PMID 18926005 DOI: 10.2170/Physiolsci.Rv003408  0.464
2008 Noble D. Computational models of the heart and their use in assessing the actions of drugs. Journal of Pharmacological Sciences. 107: 107-17. PMID 18566519 DOI: JST.JSTAGE/jphs/CR0070042  0.337
2008 Fink M, Noble D, Virag L, Varro A, Giles WR. Contributions of HERG K+ current to repolarization of the human ventricular action potential. Progress in Biophysics and Molecular Biology. 96: 357-76. PMID 17919688 DOI: 10.1016/J.Pbiomolbio.2007.07.011  0.351
2008 Liu J, Noble PJ, Xiao G, Abdelrahman M, Dobrzynski H, Boyett MR, Lei M, Noble D. Role of pacemaking current in cardiac nodes: insights from a comparative study of sinoatrial node and atrioventricular node. Progress in Biophysics and Molecular Biology. 96: 294-304. PMID 17905415 DOI: 10.1016/J.Pbiomolbio.2007.07.009  0.411
2007 Noble D, Sarai N, Noble PJ, Kobayashi T, Matsuoka S, Noma A. Resistance of cardiac cells to NCX knockout: a model study. Annals of the New York Academy of Sciences. 1099: 306-9. PMID 17446471 DOI: 10.1196/annals.1387.018  0.32
2007 Noble D. From the Hodgkin-Huxley axon to the virtual heart. The Journal of Physiology. 580: 15-22. PMID 17023502 DOI: 10.1113/jphysiol.2006.119370  0.326
2007 Noble D. Heart Rate Slowing by IfCurrent Inhibition British Journal of Clinical Pharmacology. 64: 400-400. DOI: 10.1111/J.1365-2125.2007.02924.X  0.338
2007 Sabzpoushan SH, Ayatollahi A, Noble D, Noble PJ. A survey on linear relations between main electrical components during action potential in ventricular cell Applied Mathematics and Computation. 188: 148-153. DOI: 10.1016/j.amc.2006.09.096  0.301
2006 Rodríguez B, Trayanova N, Noble D. Modeling cardiac ischemia. Annals of the New York Academy of Sciences. 1080: 395-414. PMID 17132797 DOI: 10.1196/Annals.1380.029  0.336
2006 Noble D, Noble PJ. Late sodium current in the pathophysiology of cardiovascular disease: consequences of sodium-calcium overload. Heart (British Cardiac Society). 92: iv1-iv5. PMID 16775091 DOI: 10.1136/hrt.2005.078782  0.335
2006 Fink M, Giles WR, Noble D. Contributions of inwardly rectifying K+ currents to repolarization assessed using mathematical models of human ventricular myocytes. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 364: 1207-22. PMID 16608704 DOI: 10.1098/rsta.2006.1765  0.371
2006 Noble D. Systems biology and the heart. Bio Systems. 83: 75-80. PMID 16233947 DOI: 10.1016/j.biosystems.2005.05.013  0.305
2006 Hunter PJ, Li WW, McCulloch AD, Noble D. Multiscale modeling: Physiome project standards, tools, and databases Computer. 39: 48-54. DOI: 10.1109/Mc.2006.392  0.588
2005 Noble D. The heart is already working. Biochemical Society Transactions. 33: 539-42. PMID 15916559 DOI: 10.1042/BST0330539  0.304
2005 Garny A, Noble D, Kohl P. Dimensionality in cardiac modelling. Progress in Biophysics and Molecular Biology. 87: 47-66. PMID 15471590 DOI: 10.1016/J.Pbiomolbio.2004.06.006  0.337
2004 Moore MN, Noble D. Editorial: computational modelling of cell & tissue processes & function. Journal of Molecular Histology. 35: 655-8. PMID 15614620 DOI: 10.1007/s10735-004-2653-0  0.328
2004 Noble D. Modeling the heart. Physiology (Bethesda, Md.). 19: 191-7. PMID 15304633 DOI: 10.1152/physiol.00004.2004  0.317
2004 Lei M, Jones SA, Liu J, Lancaster MK, Fung SS, Dobrzynski H, Camelliti P, Maier SK, Noble D, Boyett MR. Requirement of neuronal- and cardiac-type sodium channels for murine sinoatrial node pacemaking. The Journal of Physiology. 559: 835-48. PMID 15254155 DOI: 10.1113/Jphysiol.2004.068643  0.443
2004 Crampin EJ, Halstead M, Hunter P, Nielsen P, Noble D, Smith N, Tawhai M. Computational physiology and the Physiome Project. Experimental Physiology. 89: 1-26. PMID 15109205 DOI: 10.1113/Expphysiol.2003.026740  0.527
2004 ten Tusscher KH, Noble D, Noble PJ, Panfilov AV. A model for human ventricular tissue. American Journal of Physiology. Heart and Circulatory Physiology. 286: H1573-89. PMID 14656705 DOI: 10.1152/ajpheart.00794.2003  0.367
2003 Garny A, Kohl P, Hunter PJ, Boyett MR, Noble D. One-dimensional rabbit sinoatrial node models: benefits and limitations. Journal of Cardiovascular Electrophysiology. 14: S121-32. PMID 14760914 DOI: 10.1046/J.1540.8167.90301.X  0.501
2003 Markhasin VS, Solovyova O, Katsnelson LB, Protsenko Y, Kohl P, Noble D. Mechano-electric interactions in heterogeneous myocardium: development of fundamental experimental and theoretical models. Progress in Biophysics and Molecular Biology. 82: 207-20. PMID 12732280 DOI: 10.1016/S0079-6107(03)00017-8  0.34
2003 SOLOVYOVA O, VIKULOVA N, KATSNELSON LB, MARKHASIN VS, NOBLE PJ, GARNY A, KOHL P, NOBLE D. MECHANICAL INTERACTION OF HETEROGENEOUS CARDIAC MUSCLE SEGMENTS IN SILICO: EFFECTS ON Ca2+ HANDLING AND ACTION POTENTIAL International Journal of Bifurcation and Chaos. 13: 3757-3782. DOI: 10.1142/S0218127403008983  0.335
2003 Zhang H, Noble D, Cannell M, Orchard CH, Lancaster M, Jones SA, Boyett MR, Holden AV, Jafri MS, Sobie EA, Lederer WJ, Demir SS, Michailova A, Delprincipe F, Egger M, et al. Dynamics of cardiac intracellular Ca2+ handling - From experiments to virtual cells International Journal of Bifurcation and Chaos in Applied Sciences and Engineering. 13: 3535-3560. DOI: 10.1142/S0218127403008843  0.536
2003 GARNY A, KOHL P, NOBLE D. CELLULAR OPEN RESOURCE (COR): A PUBLIC CELLML BASED ENVIRONMENT FOR MODELING BIOLOGICAL FUNCTION International Journal of Bifurcation and Chaos. 13: 3579-3590. DOI: 10.1142/S021812740300882X  0.306
2002 Noble D. The heart cell in silico: successes, failures and prospects. Novartis Foundation Symposium. 247: 182-94; discussion 1. PMID 12539956 DOI: 10.1002/0470857897.Ch15  0.315
2002 Noble D. Influence of Na/Ca exchange stoichiometry on model cardiac action potentials. Annals of the New York Academy of Sciences. 976: 133-6. PMID 12502551 DOI: 10.1111/J.1749-6632.2002.Tb04731.X  0.351
2002 Noble D. Modelling the heart: insights, failures and progress. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 24: 1155-63. PMID 12447980 DOI: 10.1002/bies.10186  0.32
2002 Hunter P, Robbins P, Noble D. The IUPS human Physiome Project. Pflã¼Gers Archiv : European Journal of Physiology. 445: 1-9. PMID 12397380 DOI: 10.1007/S00424-002-0890-1  0.495
2002 Noble D. Unraveling the genetics and mechanisms of cardiac arrhythmia. Proceedings of the National Academy of Sciences of the United States of America. 99: 5755-6. PMID 11983875 DOI: 10.1073/pnas.102171699  0.35
2002 Noble D. Modeling the heart--from genes to cells to the whole organ. Science (New York, N.Y.). 295: 1678-82. PMID 11872832 DOI: 10.1126/science.1069881  0.306
2002 Garny A, Noble P, Kohl P, Noble D. Comparative study of rabbit sino-atrial node cell models Chaos, Solitons & Fractals. 13: 1623-1630. DOI: 10.1016/S0960-0779(01)00171-0  0.316
2001 Roux E, Noble PJ, Hyvelin JM, Noble D. Modelling of Ca2+-activated chloride current in tracheal smooth muscle cells. Acta Biotheoretica. 49: 291-300. PMID 11804240 DOI: 10.1023/A:1014230611582  0.338
2001 Noble D. From genes to whole organs: connecting biochemistry to physiology. Novartis Foundation Symposium. 239: 111-23; discussion 1. PMID 11529307 DOI: 10.1002/0470846674.Ch10  0.318
2001 Hunter PJ, Kohl P, Noble D. Correction for Hunter et al. , Integrative models of the heart: achievements and limitations Philosophical Transactions of the Royal Society of London. Series a: Mathematical, Physical and Engineering Sciences. 359: 2629-2629. DOI: 10.1098/Rsta.2001.2003  0.465
2001 Noble D, Rudy Y. Models of cardiac ventricular action potentials: Iterative interaction between experiment and simulation Philosophical Transactions of the Royal Society a: Mathematical, Physical and Engineering Sciences. 359: 1127-1142. DOI: 10.1098/Rsta.2001.0820  0.346
2001 Hunter PJ, Kohl P, Noble D. Integrative models of the heart: achievements and limitations Philosophical Transactions of the Royal Society of London. Series a: Mathematical, Physical and Engineering Sciences. 359: 1049-1054. DOI: 10.1098/Rsta.2001.0816  0.501
2000 Sakmann BF, Spindler AJ, Bryant SM, Linz KW, Noble D. Distribution of a persistent sodium current across the ventricular wall in guinea pigs. Circulation Research. 87: 910-4. PMID 11073887 DOI: 10.1161/01.Res.87.10.910  0.338
2000 Noble PJ, Noble D. Oita International Electrocardiology Symposium 2000 “Electrophysiology and Management of Lethal Arrhythmias in the New Millennium: From Genes to Bedside” Japanese Journal of Electrocardiology. 20: 15-19. DOI: 10.5105/JSE.20.SUPPL3_15  0.319
2000 Kohl P, Noble D, Winslow RL, Hunter PJ. Computational modelling of biological systems: tools and visions Philosophical Transactions of the Royal Society of London. Series a: Mathematical, Physical and Engineering Sciences. 358: 579-610. DOI: 10.1098/Rsta.2000.0547  0.531
1999 Sears EC, Noble P, Noble D, Paterson JD. Vagal control of heart rate is modulated by extracellular potassium. Journal of the Autonomic Nervous System. 77: 164-71. PMID 11130960 DOI: 10.1016/S0165-1838(99)00052-1  0.301
1999 Sears CE, Noble P, Noble D, Paterson DJ. Vagal control of heart rate is modulated by extracellular potassium. Journal of the Autonomic Nervous System. 77: 164-71. PMID 10580298  0.358
1999 Spindler AJ, Noble SJ, Noble D. Comparison of step and ramp voltage clamp on background currents in guinea-pig ventricular cells. Experimental Physiology. 84: 865-79. PMID 10502655 DOI: 10.1111/J.1469-445X.1999.01790.X  0.325
1999 Lei M, Kohl P, Brown H, Noble D. Non-muscarinic and non-nicotinic inhibition by the acetylcholine analogue carbachol of the delayed rectifier potassium current, iK, in rabbit isolated sino-atrial node cells. Experimental Physiology. 84: 631-8. PMID 10481221 DOI: 10.1111/J.1469-445X.1999.01856.X  0.414
1999 Kohl P, Hunter P, Noble D. Stretch-induced changes in heart rate and rhythm: clinical observations, experiments and mathematical models. Progress in Biophysics and Molecular Biology. 71: 91-138. PMID 10070213 DOI: 10.1016/S0079-6107(98)00038-8  0.525
1998 Ch'en FF, Vaughan-Jones RD, Clarke K, Noble D. Modelling myocardial ischaemia and reperfusion. Progress in Biophysics and Molecular Biology. 69: 515-38. PMID 9785954 DOI: 10.1016/S0079-6107(98)00023-6  0.356
1998 McCulloch A, Bassingthwaighte J, Hunter P, Noble D. Computational biology of the heart: from structure to function. Progress in Biophysics and Molecular Biology. 69: 153-5. PMID 9785936 DOI: 10.1016/S0079-6107(98)00005-4  0.615
1998 Noble D. Reduction and integration in understanding the heart. Novartis Foundation Symposium. 213: 56-68; discussion 68. PMID 9653715 DOI: 10.1002/9780470515488.Ch5  0.353
1998 Spindler AJ, Noble SJ, Noble D, LeGuennec JY. The effects of sodium substitution on currents determining the resting potential in guinea-pig ventricular cells. Experimental Physiology. 83: 121-36. PMID 9568473 DOI: 10.1113/Expphysiol.1998.Sp004096  0.335
1997 Ch'en F, Clarke K, Vaughan-Jones R, Noble D. Modeling of internal pH, ion concentration, and bioenergetic changes during myocardial ischemia. Advances in Experimental Medicine and Biology. 430: 281-90. PMID 9330737 DOI: 10.1007/978-1-4615-5959-7_24  0.311
1996 Kohl P, Noble D. Mechanosensitive connective tissue: potential influence on heart rhythm. Cardiovascular Research. 32: 62-8. PMID 8776404 DOI: 10.1016/S0008-6363(95)00224-3  0.319
1996 Noble D, LeGuennec JY, Winslow R. Functional roles of sodium-calcium exchange in normal and abnormal cardiac rhythm. Annals of the New York Academy of Sciences. 779: 480-8. PMID 8659864 DOI: 10.1111/J.1749-6632.1996.Tb44822.X  0.303
1995 Noble D. The development of mathematical models of the heart Chaos, Solitons and Fractals. 5: 321-333. DOI: 10.1016/0960-0779(93)E0025-7  0.389
1994 Guennec JVL, Noble D. Effects of rapid changes of external Na+ concentration at different moments during the action potential in guinea‐pig myocytes. The Journal of Physiology. 478: 493-504. PMID 7965859 DOI: 10.1113/Jphysiol.1994.Sp020268  0.314
1994 Kohl P, Kamkin A, Kiseleva I, Noble D. Mechanosensitive fibroblasts in the sino-atrial node region of rat heart: interaction with cardiomyocytes and possible role. Experimental Physiology. 79: 943-956. PMID 7873162 DOI: 10.1113/Expphysiol.1994.Sp003819  0.339
1993 Kiyosue T, Arita M, Muramatsu H, Spindler AJ, Noble D. Ionic mechanisms of action potential prolongation at low temperature in guinea‐pig ventricular myocytes. The Journal of Physiology. 468: 85-106. PMID 8254536 DOI: 10.1113/Jphysiol.1993.Sp019761  0.313
1993 Kiyosue T, Spindler AJ, Noble SJ, Noble D. Background inward current in ventricular and atrial cells of the guinea-pig Proceedings of the Royal Society B: Biological Sciences. 252: 65-74. PMID 7684843 DOI: 10.1098/Rspb.1993.0047  0.348
1993 Winslow RL, Kimball AL, Varghese A, Noble D. Simulating cardiac sinus and atrial network dynamics on the connection machine Physica D: Nonlinear Phenomena. 64: 281-298. DOI: 10.1016/0167-2789(93)90260-8  0.31
1992 Bett G, Noble D, Noble S, Earm Y, Ho W, So I. Na-Ca exchange current during the cardiac action potential. Advances in Experimental Medicine and Biology. 311: 453-454. PMID 1529788 DOI: 10.1007/978-1-4615-3362-7_74  0.347
1992 NOBLE D. Ionic Mechanisms Determining the Timing of Ventricular Repolarization: Significance for Cardiac Arrhythmias Annals of the New York Academy of Sciences. 644: 1-22. PMID 1314031 DOI: 10.1111/j.1749-6632.1992.tb30998.x  0.317
1992 Noble D, Denyer JC, Brown HF, DiFrancesco D. Reciprocal role of the inward currents ib, Na and i(f) in controlling and stabilizing pacemaker frequency of rabbit sino-atrial node cells. Proceedings. Biological Sciences / the Royal Society. 250: 199-207. PMID 1283636 DOI: 10.1098/rspb.1992.0150  0.309
1992 Kiyosue T, Spindler A, Noble S, Noble D. Background current, ib,Na, in guinea-pig ventricular cells Journal of Molecular and Cellular Cardiology. 24: 150. DOI: 10.1016/0022-2828(92)90474-E  0.318
1991 Noble D, Noble SJ, Bett GCL, Earm YE, Ho WK, So IK. The Role of Sodium ‐ Calcium Exchange during the Cardiac Action Potentiala Annals of the New York Academy of Sciences. 639: 334-353. PMID 1785860 DOI: 10.1111/J.1749-6632.1991.Tb17323.X  0.314
1989 Egan TM, Noble D, Noble SJ, Powell T, Spindler AJ, Twist VW. Sodium-calcium exchange during the action potential in guinea-pig ventricular cells Journal of Physiology. 411: 639-661. PMID 2482358 DOI: 10.1113/Jphysiol.1989.Sp017596  0.349
1988 Fedida D, Noble D, Spindler AJ. Use-dependent reduction and facilitation of Ca2+ current in guinea-pig myocytes. The Journal of Physiology. 405: 439-460. PMID 2855642 DOI: 10.1113/Jphysiol.1988.Sp017341  0.313
1988 Egan TM, Noble D, Noble SJ, Powell T, Twist VW, Yamaoka K. On the mechanism of isoprenaline- and forskolin-induced depolarization of single guinea-pig ventricular myocytes Journal of Physiology. 400: 299-320. PMID 2458456 DOI: 10.1113/Jphysiol.1988.Sp017121  0.335
1988 Shimoni Y, Posner P, Spindler AJ, Noble D. The effects of prenylamine on single ventricular myocytes of guinea-pig. British Journal of Pharmacology. 94: 319-324. PMID 2456114 DOI: 10.1111/J.1476-5381.1988.Tb11533.X  0.349
1988 Egan TM, Noble D, Noble SJ, Powell T, Twist VW. An isoprenaline activated sodium-dependent inward current in ventricular myocytes Nature. 328: 634-637. PMID 2441262 DOI: 10.1038/328634A0  0.355
1987 Fedida D, Noble D, Shimoni Y, Spindler AJ. Inward current related to contraction in guinea-pig ventricular myocytes. The Journal of Physiology. 385: 565-589. PMID 2443672 DOI: 10.1113/Jphysiol.1987.Sp016508  0.319
1987 Shimoni Y, Spindler AJ, Noble D. The control of calcium current reactivation by catecholamines and acetylcholine in single guinea-pig ventricular myocytes. Proceedings of the Royal Society B: Biological Sciences. 230: 267-278. PMID 2438702 DOI: 10.1098/Rspb.1987.0019  0.324
1986 Brown HF, Noble D, Noble SJ, Taupignon AI. Relationship between the transient inward current and slow inward currents in the sino-atrial node of the rabbit. The Journal of Physiology. 370: 299-315. PMID 2420976 DOI: 10.1113/jphysiol.1986.sp015936  0.345
1985 Lee KS, Noble D, Lee E, Spindler AJ. A new calcium current underlying the plateau of the cardiac action potential. Proceedings of the Royal Society of London. Series B, Biological Sciences. 223: 35-48. PMID 6151183 DOI: 10.1098/rspb.1984.0081  0.348
1985 DiFrancesco D, Noble D. A model of cardiac electrical activity incorporating ionic pumps and concentration changes. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 307: 353-98. PMID 2578676 DOI: 10.1098/Rstb.1985.0001  0.327
1985 Noble D. Ionic mechanisms in rhythmic firing of heart and nerve Trends in Neurosciences. 8: 499-504. DOI: 10.1016/0166-2236(85)90177-8  0.335
1984 Brown HF, Kimura J, Noble D, Noble SJ, Taupignon A. The ionic currents underlying pacemaker activity in rabbit sino-atrial node: experimental results and computer simulations. Proceedings of the Royal Society of London. Series B, Biological Sciences. 222: 329-47. PMID 6149555 DOI: 10.1098/rspb.1984.0067  0.36
1984 Brown HF, Kimura J, Noble D, Noble SJ, Taupignon A. The slow inward current, isi, in the rabbit sino-atrial node investigated by voltage clamp and computer simulation. Proceedings of the Royal Society of London. Series B, Biological Sciences. 222: 305-28. PMID 6149554 DOI: 10.1098/rspb.1984.0066  0.346
1984 Noble D. The surprising heart: a review of recent progress in cardiac electrophysiology Journal of Physiology. 353: 1-50. PMID 6090637 DOI: 10.1113/Jphysiol.1984.Sp015320  0.313
1983 Hart G, Noble D, Shimoni Y. The effects of low concentrations of cardiotonic steroids on membrane currents and tension in sheep Purkinje fibres. The Journal of Physiology. 334: 103-131. PMID 6864554 DOI: 10.1113/Jphysiol.1983.Sp014483  0.311
1980 Brown H, DiFrancesco D, Noble D, Noble S. The contribution of potassium accumulation to outward currents in frog atrium. The Journal of Physiology. 306: 127-49. PMID 7463357 DOI: 10.1113/Jphysiol.1980.Sp013388  0.308
1980 Noble D. Mechanism of action of therapeutic levels of cardiac glycosides Cardiovascular Research. 14: 495-514. PMID 6163538 DOI: 10.1093/CVR/14.9.495  0.312
1979 Cohen I, Noble D, Ohba M, Ojeda C. The interaction of ouabain and salicylate on sheep cardiac muscle. The Journal of Physiology. 297: 187-205. PMID 536910 DOI: 10.1113/Jphysiol.1979.Sp013034  0.322
1979 Cohen I, Noble D, Ohba M, Ojeda C. Action of salicylate ions on the electrical properties of sheep cardiac Purkinje fibres. The Journal of Physiology. 297: 163-185. PMID 536909 DOI: 10.1113/Jphysiol.1979.Sp013033  0.314
1979 Eisner DA, Lederer WJ, Noble D. Caffeine and tetracaine abolish the slow inward calcium current in sheep cardiac Purkinje fibres [proceedings]. The Journal of Physiology. 293: 76P-77P. PMID 501653  0.491
1977 Attwell D, Cohen I, Eisner DA, Noble D. Activity dependent changes in mammalian ventricular muscle [proceedings]. The Journal of Physiology. 271: 17P-18P. PMID 925971  0.429
1977 Cohen I, Eisner DA, Giles WR, Noble D. Effect of adrenaline on the potassium current reversal potential in cardiac Purkinje fibres of the sheep [proceedings]. The Journal of Physiology. 272: 53P-54P. PMID 592151  0.505
1976 Brown HF, Noble D, Noble SJ. The influence of non-uniformity on the analysis of potassium currents in heart muscle. The Journal of Physiology. 258: 615-29. PMID 1086358 DOI: 10.1113/jphysiol.1976.sp011437  0.346
1975 McAllister RE, Noble D, Tsien RW. Reconstruction of the electrical activity of cardiac Purkinje fibres. The Journal of Physiology. 251: 1-59. PMID 1185607 DOI: 10.1113/jphysiol.1975.sp011080  0.563
1975 Hunter PJ, McNaughton PA, Noble D. Analytical models of propagation in excitable cells. Progress in Biophysics and Molecular Biology. 30: 99-144. PMID 792954 DOI: 10.1016/0079-6107(76)90007-9  0.46
1975 Brown HF, McNaughton PA, Noble D, Noble SJ. Adrenergic control of cardian pacemaker currents. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 270: 527-37. PMID 238248 DOI: 10.1098/RSTB.1975.0029  0.366
1972 Hauswirth O, Noble D, Tsien RW. Separation of the pace-maker and plateau components of delayed rectification in cardiac Purkinje fibres. The Journal of Physiology. 225: 211-35. PMID 4679715 DOI: 10.1113/jphysiol.1972.sp009934  0.544
1972 Hausworth O, Noble D, Tsien RW. The dependence of plateau currents in cardiac Purkinje fibres on the interval between action potentials. The Journal of Physiology. 222: 27-49. PMID 4113958 DOI: 10.1113/jphysiol.1972.sp009786  0.549
1969 Tsien RW, Noble D. A transition state theory approach to the kinetics of conductance changes in excitable membranes. The Journal of Membrane Biology. 1: 248-73. PMID 24174053 DOI: 10.1007/BF01869785  0.437
1969 Hauswirth O, McAllister RE, Noble D, Tsien RW. Reconstruction of the actions of adrenaline and calcium on cardiac pacemaker potentials. The Journal of Physiology. 204: 126P+. PMID 5824627  0.472
1969 Hauswirth O, Noble D, Tsien RW. The mechanism of oscillatory activity at low membrane potentials in cardiac Purkinje fibres. The Journal of Physiology. 200: 255-65. PMID 5761950 DOI: 10.1113/jphysiol.1969.sp008691  0.552
1969 Noble D, Tsien RW. Reconstruction of the repolarization process in cardiac Purkinje fibres based on voltage clamp measurements of membrane current. The Journal of Physiology. 200: 233-54. PMID 5761948 DOI: 10.1113/jphysiol.1969.sp008690  0.545
1969 Noble D, Tsien RW. Outward membrane currents activated in the plateau range of potentials in cardiac Purkinje fibres. The Journal of Physiology. 200: 205-31. PMID 5761944 DOI: 10.1113/jphysiol.1969.sp008689  0.551
1968 Noble D, Tsien RW. The kinetics and rectifier properties of the slow potassium current in cardiac Purkinje fibres. The Journal of Physiology. 195: 185-214. PMID 5639799 DOI: 10.1113/jphysiol.1968.sp008454  0.547
1968 Noble D, Tsien RW. Kinetics of slow component of potassium current in cardiac purkinje fibres. The Journal of Physiology. 194: 31P-32P. PMID 5639778  0.495
1968 Hauswirth O, Noble D, Tsien RW. Adrenaline: mechanism of action on the pacemaker potential in cardiac Purkinje fibers. Science (New York, N.Y.). 162: 916-7. PMID 4386717 DOI: 10.1126/Science.162.3856.916  0.546
1966 Noble D, Stein RB. The threshold conditions for initiation of action potentials by excitable cells. The Journal of Physiology. 187: 129-62. PMID 16992236 DOI: 10.1113/jphysiol.1966.sp008079  0.442
1963 Hall AE, Noble D. Transient responses of purkinje fibres to non-uniform currents [30] Nature. 199: 1294-1295. PMID 14074602 DOI: 10.1038/1991294a0  0.332
1963 HALL AE, HUTTER OF, NOBLE D. Current-voltage relations of Purkinje fibres in sodium-deficient solutions. The Journal of Physiology. 166: 225-40. PMID 13960731 DOI: 10.1113/jphysiol.1963.sp007102  0.643
1962 Noble D. The Voltage Dependence of the Cardiac Membrane Conductance Biophysical Journal. 2: 381-393. PMID 14480152 DOI: 10.1016/S0006-3495(62)86862-3  0.305
1961 HUTTER OF, NOBLE D. Anion conductance of cardiac muscle. The Journal of Physiology. 157: 335-50. PMID 13717087 DOI: 10.1113/jphysiol.1961.sp006726  0.649
1960 HUTTER OF, NOBLE D. The chloride conductance of frog skeletal muscle. The Journal of Physiology. 151: 89-102. PMID 14405647 DOI: 10.1113/jphysiol.1960.sp006424  0.593
1960 HUTTER OF, NOBLE D. Rectifying properties of heart muscle. Nature. 188: 495. PMID 13717088 DOI: 10.1038/188495a0  0.669
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