| Year |
Citation |
Score |
| 2020 |
DelGiorno KE, Chung CY, Vavinskaya V, Maurer HC, Novak SW, Lytle NK, Ma Z, Giraddi RR, Wang D, Fang L, Naeem RF, Andrade LR, Ali WH, Tseng H, Tsui C, ... ... Wahl GM, et al. Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D2. Gastroenterology. PMID 32717220 DOI: 10.1053/J.Gastro.2020.07.037 |
0.333 |
|
| 2020 |
Christin JR, Wang C, Chung CY, Liu Y, Dravis C, Tang W, Oktay MH, Wahl GM, Guo W. Stem Cell Determinant SOX9 Promotes Lineage Plasticity and Progression in Basal-like Breast Cancer. Cell Reports. 31: 107742. PMID 32521267 DOI: 10.1016/J.Celrep.2020.107742 |
0.394 |
|
| 2020 |
Badgley MA, Kremer DM, Maurer HC, DelGiorno KE, Lee HJ, Purohit V, Sagalovskiy IR, Ma A, Kapilian J, Firl CEM, Decker AR, Sastra SA, Palermo CF, Andrade LR, Sajjakulnukit P, ... ... Wahl GM, et al. Cysteine depletion induces pancreatic tumor ferroptosis in mice. Science (New York, N.Y.). 368: 85-89. PMID 32241947 DOI: 10.1126/Science.Aaw9872 |
0.324 |
|
| 2020 |
DelGiorno KE, Naeem RF, Fang L, Chung CY, Ramos C, Luhtala N, O'Connor C, Hunter T, Manor U, Wahl GM. Tuft Cell Formation Reflects Epithelial Plasticity in Pancreatic Injury: Implications for Modeling Human Pancreatitis. Frontiers in Physiology. 11: 88. PMID 32116793 DOI: 10.3389/Fphys.2020.00088 |
0.323 |
|
| 2020 |
Badgley M, DelGiorno K, Wahl G, Lyssiotis C, Olive KP. Abstract 5711: Therapeutic induction of tumor-selective ferroptosis in models of pancreatic cancer Cancer Research. 80: 5711-5711. DOI: 10.1158/1538-7445.Am2020-5711 |
0.388 |
|
| 2019 |
Chung CY, Ma Z, Dravis C, Preissl S, Poirion O, Luna G, Hou X, Giraddi RR, Ren B, Wahl GM. Single-Cell Chromatin Analysis of Mammary Gland Development Reveals Cell-State Transcriptional Regulators and Lineage Relationships. Cell Reports. 29: 495-510.e6. PMID 31597106 DOI: 10.1016/J.Celrep.2019.08.089 |
0.393 |
|
| 2019 |
Shi Y, Gao W, Lytle NK, Huang P, Yuan X, Dann AM, Ridinger-Saison M, DelGiorno KE, Antal CE, Liang G, Atkins AR, Erikson G, Sun H, Meisenhelder J, Terenziani E, ... ... Wahl GM, et al. Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring. Nature. PMID 30996350 DOI: 10.1038/S41586-019-1130-6 |
0.369 |
|
| 2019 |
DelGiorno KE, Chung C, Giraddi R, Ke E, Maurer HC, Ridinger-Saison M, Ali WH, Tsui C, Ramos C, Naeem R, Ohmoto M, Fang L, Luna G, Fitzpatrick C, O'Connor C, ... ... Wahl GM, et al. Abstract 5169: Pancreatic tumorigenesis evokes mechanisms of tissue injury and repair Cancer Research. 79: 5169-5169. DOI: 10.1158/1538-7445.Am2019-5169 |
0.383 |
|
| 2018 |
Dravis C, Chung CY, Lytle NK, Herrera-Valdez J, Luna G, Trejo CL, Reya T, Wahl GM. Epigenetic and Transcriptomic Profiling of Mammary Gland Development and Tumor Models Disclose Regulators of Cell State Plasticity. Cancer Cell. PMID 30174241 DOI: 10.1016/J.Ccell.2018.08.001 |
0.399 |
|
| 2018 |
Giraddi RR, Chung CY, Heinz RE, Balcioglu O, Novotny M, Trejo CL, Dravis C, Hagos BM, Mehrabad EM, Rodewald LW, Hwang JY, Fan C, Lasken R, Varley KE, Perou CM, ... Wahl GM, et al. Single-Cell Transcriptomes Distinguish Stem Cell State Changes and Lineage Specification Programs in Early Mammary Gland Development. Cell Reports. 24: 1653-1666.e7. PMID 30089273 DOI: 10.1016/J.Celrep.2018.07.025 |
0.396 |
|
| 2018 |
Dravis C, Wahl G. Abstract B64: Sox10 drives tumor progression in breast cancer by reprogramming mammary tumor cells into a state of plasticity resembling primitive neural crest cells Molecular Cancer Research. 16. DOI: 10.1158/1557-3125.Advbc17-B64 |
0.377 |
|
| 2017 |
Saison-Ridinger M, DelGiorno KE, Zhang T, Kraus A, French R, Jaquish D, Tsui C, Erikson G, Spike BT, Shokhirev MN, Liddle C, Yu RT, Downes M, Evans RM, Saghatelian A, ... ... Wahl GM, et al. Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy. Plos One. 12: e0189051. PMID 29211796 DOI: 10.1371/Journal.Pone.0189051 |
0.418 |
|
| 2017 |
Turner KM, Deshpande V, Beyter D, Koga T, Rusert J, Lee C, Li B, Arden K, Ren B, Nathanson DA, Kornblum HI, Taylor MD, Kaushal S, Cavenee WK, Wechsler-Reya R, ... ... Wahl GM, et al. Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity. Nature. PMID 28178237 DOI: 10.1038/Nature21356 |
0.394 |
|
| 2016 |
Sancho-Martinez I, Nivet E, Xia Y, Hishida T, Aguirre A, Ocampo A, Ma L, Morey R, Krause MN, Zembrzycki A, Ansorge O, Vazquez-Ferrer E, Dubova I, Reddy P, Lam D, ... ... Wahl GM, et al. Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. Nature Communications. 7: 10743. PMID 26899176 DOI: 10.1038/Ncomms10743 |
0.384 |
|
| 2016 |
Dravis C, Wahl GM. Abstract IA10: Sox10 regulates stem/progenitor and mesenchymal cell states in mammary epithelial cells Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Advbc15-Ia10 |
0.377 |
|
| 2016 |
Ridinger M, Evans RM, Saghatelian A, Lowy AM, Wahl GM. Abstract B24: p53 mediates reprograming of cancer-associated fibroblasts in pancreatic cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-B24 |
0.428 |
|
| 2016 |
Dravis C, Wahl GM. Abstract 914: Sox10 regulates stem- and mesenchymal-like features in mammary cells Cancer Research. 76: 914-914. DOI: 10.1158/1538-7445.Am2016-914 |
0.381 |
|
| 2015 |
Dravis C, Spike BT, Harrell JC, Johns C, Trejo CL, Southard-Smith EM, Perou CM, Wahl GM. Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells. Cell Reports. 12: 2035-48. PMID 26365194 DOI: 10.1016/J.Celrep.2015.08.040 |
0.373 |
|
| 2015 |
Adams CJ, Yu JS, Mao JH, Jen KY, Costes SV, Wade M, Shoemake J, Aina OH, Del Rosario R, Menchavez PT, Cardiff RD, Wahl GM, Balmain A. The Trp53 delta proline (Trp53ΔP) mouse exhibits increased genome instability and susceptibility to radiation-induced, but not spontaneous, tumor development. Molecular Carcinogenesis. PMID 26310697 DOI: 10.1002/Mc.22377 |
0.334 |
|
| 2015 |
Rozhok AI, Wahl GM, DeGregori J. A Critical Examination of the "Bad Luck" Explanation of Cancer Risk. Cancer Prevention Research (Philadelphia, Pa.). 8: 762-4. PMID 26122457 DOI: 10.1158/1940-6207.Capr-15-0229 |
0.328 |
|
| 2015 |
Ridinger M, Kraus A, Cox M, Wade M, Liddle C, Downes M, Evans R, Wahl G. Abstract B10: Function and therapeutic implications of p53 in the stroma of pancreatic cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-B10 |
0.32 |
|
| 2015 |
Dravis C, Wahl GM. Abstract 2326: Sox10 promotes both stem-like and EMT properties in mammary cells Cancer Research. 75: 2326-2326. DOI: 10.1158/1538-7445.Am2015-2326 |
0.393 |
|
| 2014 |
Li YC, Rodewald LW, Hoppmann C, Wong ET, Lebreton S, Safar P, Patek M, Wang L, Wertman KF, Wahl GM. A versatile platform to analyze low-affinity and transient protein-protein interactions in living cells in real time. Cell Reports. 9: 1946-58. PMID 25464845 DOI: 10.1016/J.Celrep.2014.10.058 |
0.601 |
|
| 2014 |
Sherman MH, Yu RT, Engle DD, Ding N, Atkins AR, Tiriac H, Collisson EA, Connor F, Van Dyke T, Kozlov S, Martin P, Tseng TW, Dawson DW, Donahue TR, Masamune A, ... ... Wahl GM, et al. Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy. Cell. 159: 80-93. PMID 25259922 DOI: 10.1016/J.Cell.2014.08.007 |
0.678 |
|
| 2014 |
Spike BT, Kelber JA, Booker E, Kalathur M, Rodewald R, Lipianskaya J, La J, He M, Wright T, Klemke R, Wahl GM, Gray PC. CRIPTO/GRP78 signaling maintains fetal and adult mammary stem cells ex vivo. Stem Cell Reports. 2: 427-39. PMID 24749068 DOI: 10.1016/J.Stemcr.2014.02.010 |
0.363 |
|
| 2014 |
He G, Zhang YW, Lee JH, Zeng SX, Wang YV, Luo Z, Dong XC, Viollet B, Wahl GM, Lu H. AMP-activated protein kinase induces p53 by phosphorylating MDMX and inhibiting its activity. Molecular and Cellular Biology. 34: 148-57. PMID 24190973 DOI: 10.1128/Mcb.00670-13 |
0.367 |
|
| 2014 |
Spike BT, Kelber JA, Booker E, Kalathur M, Rodewald R, Lipianskaya J, La J, He M, Wright T, Klemke R, Wahl G, Gray PC. Abstract 3035: Cripto/GRP78 signaling promotes the stem cell phenotype in normal and neoplastic mammary epithelial cells Cancer Research. 74: 3035-3035. DOI: 10.1158/1538-7445.Am2014-3035 |
0.413 |
|
| 2013 |
Pfefferle AD, Herschkowitz JI, Usary J, Harrell JC, Spike BT, Adams JR, Torres-Arzayus MI, Brown M, Egan SE, Wahl GM, Rosen JM, Perou CM. Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts. Genome Biology. 14: R125. PMID 24220145 DOI: 10.1186/Gb-2013-14-11-R125 |
0.323 |
|
| 2013 |
Makarem M, Spike BT, Dravis C, Kannan N, Wahl GM, Eaves CJ. Stem cells and the developing mammary gland. Journal of Mammary Gland Biology and Neoplasia. 18: 209-19. PMID 23624881 DOI: 10.1007/S10911-013-9284-6 |
0.387 |
|
| 2013 |
Green JL, La J, Yum KW, Desai P, Rodewald LW, Zhang X, Leblanc M, Nusse R, Lewis MT, Wahl GM. Paracrine Wnt signaling both promotes and inhibits human breast tumor growth. Proceedings of the National Academy of Sciences of the United States of America. 110: 6991-6. PMID 23559372 DOI: 10.1073/Pnas.1303671110 |
0.352 |
|
| 2013 |
Green JL, Bauer M, Yum KW, Li YC, Cox ML, Willert K, Wahl GM. Use of a molecular genetic platform technology to produce human Wnt proteins reveals distinct local and distal signaling abilities. Plos One. 8: e58395. PMID 23516471 DOI: 10.1371/Journal.Pone.0058395 |
0.354 |
|
| 2013 |
Wade M, Li YC, Wahl GM. MDM2, MDMX and p53 in oncogenesis and cancer therapy. Nature Reviews. Cancer. 13: 83-96. PMID 23303139 DOI: 10.1038/Nrc3430 |
0.358 |
|
| 2013 |
Wahl GM, Dravis C, Johns C, Rodewald R, Spike BT, Trejo C. Abstract IA11: Dissecting cancer through the lens of development Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-Ia11 |
0.392 |
|
| 2013 |
Dravis C, Johns C, Spike BT, Smith MS, Wahl GM. Abstract B136: Sox10 expression labels in vitro mammary stem cell activity Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-B136 |
0.39 |
|
| 2013 |
Spike BT, Engle DD, Lin JC, Kelber JA, La J, Cheung SK, Booker E, Rodewald R, Dravis C, Gray PC, Wahl GM. Abstract A136: Deconstructing stemness from the fetal mammary perspective Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-A136 |
0.718 |
|
| 2012 |
Li YC, Wahl GM. What a difference a phosphate makes: life or death decided by a single amino acid in MDM2. Cancer Cell. 21: 595-6. PMID 22624708 DOI: 10.1016/J.Ccr.2012.04.033 |
0.345 |
|
| 2012 |
Lee JH, Jin Y, He G, Zeng SX, Wang YV, Wahl GM, Lu H. Hypoxia activates tumor suppressor p53 by inducing ATR-Chk1 kinase cascade-mediated phosphorylation and consequent 14-3-3γ inactivation of MDMX protein. The Journal of Biological Chemistry. 287: 20898-903. PMID 22556425 DOI: 10.1074/Jbc.M111.336875 |
0.379 |
|
| 2012 |
Spike BT, Engle DD, Lin JC, Cheung SK, La J, Wahl GM. A mammary stem cell population identified and characterized in late embryogenesis reveals similarities to human breast cancer. Cell Stem Cell. 10: 183-97. PMID 22305568 DOI: 10.1016/J.Stem.2011.12.018 |
0.711 |
|
| 2012 |
Wade M, Li YC, Matani AS, Braun SM, Milanesi F, Rodewald LW, Wahl GM. Functional analysis and consequences of Mdm2 E3 ligase inhibition in human tumor cells. Oncogene. 31: 4789-97. PMID 22266850 DOI: 10.1038/Onc.2011.625 |
0.404 |
|
| 2012 |
Wahl G, Spike B, Engle D, Lin J, Cheung S, La J. Stem cells, cancer, and cancer stem cells F1000research. 3. DOI: 10.7490/F1000Research.1089958.1 |
0.694 |
|
| 2012 |
Spike BT, Kelber JA, Kalathur M, Booker E, Lipianskaya J, Klemke R, Vale W, Wahl G, Gray PC. Abstract 3493: Soluble ALK4 extracellular domain antagonizes the cancer/stem cell phenotype caused by Nodal and Cripto signaling in mammary epithelia Cancer Research. 72: 3493-3493. DOI: 10.1158/1538-7445.Am2012-3493 |
0.411 |
|
| 2012 |
Spike BT, Engle DD, Lin JC, La J, Cheung SK, Wahl GM. Abstract 1015: Mammary stem cells increase late in embryogenesis, facilitating their characterization and revealing links to breast cancer Cancer Research. 72: 1015-1015. DOI: 10.1158/1538-7445.Am2012-1015 |
0.713 |
|
| 2011 |
Spike BT, Wahl GM. p53, Stem Cells, and Reprogramming: Tumor Suppression beyond Guarding the Genome. Genes & Cancer. 2: 404-19. PMID 21779509 DOI: 10.1177/1947601911410224 |
0.441 |
|
| 2011 |
Wang YV, Leblanc M, Fox N, Mao JH, Tinkum KL, Krummel K, Engle D, Piwnica-Worms D, Piwnica-Worms H, Balmain A, Kaushansky K, Wahl GM. Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity. Genes & Development. 25: 1426-38. PMID 21724834 DOI: 10.1101/Gad.2024411 |
0.75 |
|
| 2010 |
Mizuno H, Spike BT, Wahl GM, Levine AJ. Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures. Proceedings of the National Academy of Sciences of the United States of America. 107: 22745-50. PMID 21149740 DOI: 10.1073/Pnas.1017001108 |
0.433 |
|
| 2010 |
Bernal F, Wade M, Godes M, Davis TN, Whitehead DG, Kung AL, Wahl GM, Walensky LD. A stapled p53 helix overcomes HDMX-mediated suppression of p53. Cancer Cell. 18: 411-22. PMID 21075307 DOI: 10.1016/J.Ccr.2010.10.024 |
0.412 |
|
| 2010 |
Wade M, Wang YV, Wahl GM. The p53 orchestra: Mdm2 and Mdmx set the tone. Trends in Cell Biology. 20: 299-309. PMID 20172729 DOI: 10.1016/J.Tcb.2010.01.009 |
0.419 |
|
| 2010 |
Spike BT, Kelber JA, Booker EC, Klemke RL, Wahl GM, Vale WW, Gray PC. Abstract 4006: Soluble ALK4 extracellular domain antagonizes oncogenic Cripto signaling and inhibits tumor growth Cancer Research. 70: 4006-4006. DOI: 10.1158/1538-7445.Am10-4006 |
0.352 |
|
| 2010 |
Yu J, Mao J, Wade M, Del Rosario R, Wu D, Cardiff R, Wahl G, Balmain A. Mice Lacking the Proline-rich Domain of p53 Are Exquisitely Sensitive to Epithelial Tumor Development after Gamma-Irradiation International Journal of Radiation Oncology*Biology*Physics. 78: S88-S89. DOI: 10.1016/J.Ijrobp.2010.07.236 |
0.308 |
|
| 2009 |
Wang YV, Wade M, Wahl GM. Guarding the guardian: Mdmx plays important roles in setting p53 basal activity and determining biological responses in vivo. Cell Cycle (Georgetown, Tex.). 8: 3443-4. PMID 19838055 DOI: 10.4161/Cc.8.21.9744 |
0.489 |
|
| 2009 |
Ponnamperuma RM, King KE, Elsir T, Glick AB, Wahl GM, Nister M, Weinberg WC. The transcriptional regulatory function of p53 is essential for suppression of mouse skin carcinogenesis and can be dissociated from effects on TGF-β-mediated growth regulation Journal of Pathology. 219: 263-274. PMID 19718706 DOI: 10.1002/Path.2600 |
0.399 |
|
| 2009 |
Kawamura T, Suzuki J, Wang YV, Menendez S, Morera LB, Raya A, Wahl GM, Izpisúa Belmonte JC. Linking the p53 tumour suppressor pathway to somatic cell reprogramming. Nature. 460: 1140-4. PMID 19668186 DOI: 10.1038/Nature08311 |
0.459 |
|
| 2009 |
Wang YV, Leblanc M, Wade M, Jochemsen AG, Wahl GM. Increased radioresistance and accelerated B cell lymphomas in mice with Mdmx mutations that prevent modifications by DNA-damage-activated kinases. Cancer Cell. 16: 33-43. PMID 19573810 DOI: 10.1016/J.Ccr.2009.05.008 |
0.422 |
|
| 2009 |
Wade M, Wahl GM. Targeting Mdm2 and Mdmx in cancer therapy: better living through medicinal chemistry? Molecular Cancer Research : McR. 7: 1-11. PMID 19147532 DOI: 10.1158/1541-7786.Mcr-08-0423 |
0.426 |
|
| 2009 |
Bernal F, Wade M, Wahl GM, Walensky LD. Abstract C174: Therapeutic reactivation of p53 through dual targeting of HDM2 and HDMX with a stapled p53 peptide Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-C174 |
0.467 |
|
| 2008 |
Wade M, Rodewald LW, Espinosa JM, Wahl GM. BH3 activation blocks Hdmx suppression of apoptosis and cooperates with Nutlin to induce cell death. Cell Cycle (Georgetown, Tex.). 7: 1973-82. PMID 18604177 DOI: 10.4161/Cc.7.13.6072 |
0.399 |
|
| 2008 |
Bernal F, Wade M, Silverstein AM, Verdine GL, Wahl GM, Walensky LD. A Stapled p53 Helix Targets HDMX to Overcome Nutlin-3 Resistance and Reactivate the p53 Tumor Suppressor Pathway in Cancer Blood. 112: 2645-2645. DOI: 10.1182/Blood.V112.11.2645.2645 |
0.465 |
|
| 2007 |
Wang YV, Wade M, Wong E, Li YC, Rodewald LW, Wahl GM. Quantitative analyses reveal the importance of regulated Hdmx degradation for p53 activation. Proceedings of the National Academy of Sciences of the United States of America. 104: 12365-70. PMID 17640893 DOI: 10.1073/Pnas.0701497104 |
0.444 |
|
| 2007 |
Toledo F, Wahl GM. MDM2 and MDM4: p53 regulators as targets in anticancer therapy. The International Journal of Biochemistry & Cell Biology. 39: 1476-82. PMID 17499002 DOI: 10.1016/J.Biocel.2007.03.022 |
0.441 |
|
| 2007 |
Toledo F, Lee CJ, Krummel KA, Rodewald LW, Liu CW, Wahl GM. Mouse mutants reveal that putative protein interaction sites in the p53 proline-rich domain are dispensable for tumor suppression. Molecular and Cellular Biology. 27: 1425-32. PMID 17158931 DOI: 10.1128/Mcb.00999-06 |
0.407 |
|
| 2007 |
Wahl GM. Mouse bites dogma: how mouse models are changing our views of how P53 is regulated in vivo. Cell Death and Differentiation. 13: 973-83. PMID 16575406 DOI: 10.1038/Sj.Cdd.4401911 |
0.408 |
|
| 2006 |
Toledo F, Wahl GM. Regulating the p53 pathway: in vitro hypotheses, in vivo veritas. Nature Reviews. Cancer. 6: 909-23. PMID 17128209 DOI: 10.1038/Nrc2012 |
0.414 |
|
| 2006 |
Clarke MF, Dick JE, Dirks PB, Eaves CJ, Jamieson CH, Jones DL, Visvader J, Weissman IL, Wahl GM. Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Research. 66: 9339-44. PMID 16990346 DOI: 10.1158/0008-5472.Can-06-3126 |
0.355 |
|
| 2006 |
Wade M, Wong ET, Tang M, Stommel JM, Wahl GM. Hdmx modulates the outcome of p53 activation in human tumor cells. The Journal of Biological Chemistry. 281: 33036-44. PMID 16905769 DOI: 10.1074/Jbc.M605405200 |
0.798 |
|
| 2006 |
Toledo F, Liu CW, Lee CJ, Wahl GM. RMCE-ASAP: a gene targeting method for ES and somatic cells to accelerate phenotype analyses. Nucleic Acids Research. 34: e92. PMID 16870721 DOI: 10.1093/Nar/Gkl518 |
0.382 |
|
| 2006 |
Wade M, Wahl GM. c-Myc, genome instability, and tumorigenesis: the devil is in the details. Current Topics in Microbiology and Immunology. 302: 169-203. PMID 16620029 DOI: 10.1007/3-540-32952-8_7 |
0.347 |
|
| 2006 |
Toledo F, Krummel KA, Lee CJ, Liu CW, Rodewald LW, Tang M, Wahl GM. A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network. Cancer Cell. 9: 273-85. PMID 16616333 DOI: 10.1016/J.Ccr.2006.03.014 |
0.414 |
|
| 2006 |
Tang M, Wahl GM, Nistér M. Explaining the biological activity of transactivation-deficient p53 variants. Nature Genetics. 38: 395-6; author reply . PMID 16570054 DOI: 10.1038/Ng0406-395 |
0.304 |
|
| 2006 |
Marine J, Francoz S, Maetens M, Wahl G, Toledo F, Lozano G. Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4. Cell Death & Differentiation. 13: 927-934. PMID 16543935 DOI: 10.1038/Sj.Cdd.4401912 |
0.312 |
|
| 2006 |
Burhans WC, Carr AM, Wahl GM. 24 DNA Replication and Cancer Cold Spring Harbor Monograph Archive. 47: 481-500. DOI: 10.1101/087969766.47.481 |
0.42 |
|
| 2005 |
Wong ET, Kolman JL, Li YC, Mesner LD, Hillen W, Berens C, Wahl GM. Reproducible doxycycline-inducible transgene expression at specific loci generated by Cre-recombinase mediated cassette exchange. Nucleic Acids Research. 33: e147. PMID 16204450 DOI: 10.1093/Nar/Gni145 |
0.638 |
|
| 2005 |
Buzina A, Aladjem MI, Kolman JL, Wahl GM, Ellis J. Initiation of DNA replication at the human beta-globin 3' enhancer. Nucleic Acids Research. 33: 4412-24. PMID 16085752 DOI: 10.1093/Nar/Gki747 |
0.361 |
|
| 2005 |
Krummel KA, Lee CJ, Toledo F, Wahl GM. The C-terminal lysines fine-tune P53 stress responses in a mouse model but are not required for stability control or transactivation. Proceedings of the National Academy of Sciences of the United States of America. 102: 10188-93. PMID 16006521 DOI: 10.1073/Pnas.0503068102 |
0.441 |
|
| 2005 |
Nistér M, Tang M, Zhang XQ, Yin C, Beeche M, Hu X, Enblad G, van Dyke T, Wahl GM. p53 must be competent for transcriptional regulation to suppress tumor formation. Oncogene. 24: 3563-73. PMID 15750633 DOI: 10.1038/Sj.Onc.1208354 |
0.396 |
|
| 2005 |
Stommel JM, Wahl GM. A new twist in the feedback loop: stress-activated MDM2 destabilization is required for p53 activation. Cell Cycle (Georgetown, Tex.). 4: 411-7. PMID 15684615 DOI: 10.4161/Cc.4.3.1522 |
0.768 |
|
| 2005 |
Jimenez GS, Nister M, Beeche M, Stommel JS, Barcarse E, O'Gorman S, Wahl GM. Erratum: Corrigendum: A transactivation-deficient mouse model provides insight into p53 regulation and function Nature Genetics. 37: 205-205. DOI: 10.1038/Ng0205-205A |
0.378 |
|
| 2004 |
Thompson T, Tovar C, Yang H, Carvajal D, Vu BT, Xu Q, Wahl GM, Heimbrook DC, Vassilev LT. Phosphorylation of p53 on key serines is dispensable for transcriptional activation and apoptosis. The Journal of Biological Chemistry. 279: 53015-22. PMID 15471885 DOI: 10.1074/Jbc.M410233200 |
0.411 |
|
| 2004 |
Yamamoto N, Jiang P, Yang M, Xu M, Yamauchi K, Tsuchiya H, Tomita K, Wahl GM, Moossa AR, Hoffman RM. Cellular dynamics visualized in live cells in vitro and in vivo by differential dual-color nuclear-cytoplasmic fluorescent-protein expression. Cancer Research. 64: 4251-6. PMID 15205338 DOI: 10.1158/0008-5472.Can-04-0643 |
0.336 |
|
| 2004 |
Stommel JM, Wahl GM. Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activation. The Embo Journal. 23: 1547-56. PMID 15029243 DOI: 10.1038/Sj.Emboj.7600145 |
0.77 |
|
| 2003 |
Sears J, Kolman J, Wahl GM, Aiyar A. Metaphase chromosome tethering is necessary for the DNA synthesis and maintenance of oriP plasmids but is insufficient for transcription activation by Epstein-Barr nuclear antigen 1. Journal of Virology. 77: 11767-80. PMID 14557661 DOI: 10.1128/Jvi.77.21.11767-11780.2003 |
0.366 |
|
| 2003 |
Wahl G, Vafa O. Genetic instability, oncogenes, and the p53 pathway. Cold Spring Harbor Symposia On Quantitative Biology. 65: 511-20. PMID 12760068 DOI: 10.1101/Sqb.2000.65.511 |
0.322 |
|
| 2002 |
Neuteboom ST, Karjian PL, Boyer CR, Beryt M, Pegram M, Wahl GM, Shepard HM. Inhibition of cell growth by NB1011 requires high thymidylate synthase levels and correlates with p53, p21, bax, and GADD45 induction. Molecular Cancer Therapeutics. 1: 377-84. PMID 12477050 |
0.364 |
|
| 2002 |
Tergaonkar V, Pando M, Vafa O, Wahl G, Verma I. p53 stabilization is decreased upon NFkappaB activation: a role for NFkappaB in acquisition of resistance to chemotherapy. Cancer Cell. 1: 493-503. PMID 12124178 DOI: 10.1016/S1535-6108(02)00068-5 |
0.395 |
|
| 2002 |
Vafa O, Wade M, Kern S, Beeche M, Pandita TK, Hampton GM, Wahl GM. c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability. Molecular Cell. 9: 1031-44. PMID 12049739 DOI: 10.1016/S1097-2765(02)00520-8 |
0.417 |
|
| 2002 |
Boyer CR, Karjian PL, Wahl GM, Pegram M, Neuteboom ST. Nucleoside transport inhibitors, dipyridamole and p-nitrobenzylthioinosine, selectively potentiate the antitumor activity of NB1011. Anti-Cancer Drugs. 13: 29-36. PMID 11914638 DOI: 10.1097/00001813-200201000-00003 |
0.378 |
|
| 2002 |
Aladjem MI, Rodewald LW, Lin CM, Bowman S, Cimbora DM, Brody LL, Epner EM, Groudine M, Wahl GM. Replication initiation patterns in the beta-globin loci of totipotent and differentiated murine cells: evidence for multiple initiation regions. Molecular and Cellular Biology. 22: 442-52. PMID 11756541 DOI: 10.1128/Mcb.22.2.442-452.2002 |
0.382 |
|
| 2001 |
Wahl GM, Carr AM. The evolution of diverse biological responses to DNA damage: insights from yeast and p53. Nature Cell Biology. 3: E277-86. PMID 11781586 DOI: 10.1038/Ncb1201-E277 |
0.426 |
|
| 2001 |
Kanda T, Wahl GM. The dynamics of acentric chromosomes in cancer cells revealed by GFP-based chromosome labeling strategies. Journal of Cellular Biochemistry. Supplement. 107-14. PMID 11389539 DOI: 10.1002/1097-4644(2000)79:35+<107::Aid-Jcb1133>3.0.Co;2-Y |
0.371 |
|
| 2001 |
Kanda T, Otter M, Wahl GM. Coupling of mitotic chromosome tethering and replication competence in epstein-barr virus-based plasmids. Molecular and Cellular Biology. 21: 3576-88. PMID 11313483 DOI: 10.1128/Mcb.21.10.3576-3588.2001 |
0.327 |
|
| 2000 |
Jimenez GS, Nister M, Stommel JM, Beeche M, Barcarse EA, Zhang XQ, O'Gorman S, Wahl GM. A transactivation-deficient mouse model provides insights into Trp53 regulation and function. Nature Genetics. 26: 37-43. PMID 10973245 DOI: 10.1038/79152 |
0.747 |
|
| 2000 |
Khan SH, Moritsugu J, Wahl GM. Differential requirement for p19ARF in the p53-dependent arrest induced by DNA damage, microtubule disruption, and ribonucleotide depletion. Proceedings of the National Academy of Sciences of the United States of America. 97: 3266-71. PMID 10716710 DOI: 10.1073/pnas.050560997 |
0.346 |
|
| 2000 |
Khan SH, Moritsugu J, Wahl GM. Differential requirement for p19ARF in the p53-dependent arrest induced by DNA damage, microtubule disruption, and ribonucleotide depletion Proceedings of the National Academy of Sciences. 97: 3266-3271. DOI: 10.1073/Pnas.97.7.3266 |
0.452 |
|
| 1999 |
Jimenez GS, Khan SH, Stommel JM, Wahl GM. p53 regulation by post-translational modification and nuclear retention in response to diverse stresses. Oncogene. 18: 7656-65. PMID 10618705 DOI: 10.1038/Sj.Onc.1203013 |
0.746 |
|
| 1999 |
Jimenez GS, Bryntesson F, Torres-Arzayus MI, Priestley A, Beeche M, Saito S, Sakaguchi K, Appella E, Jeggo PA, Taccioli GE, Wahl GM, Hubank M. DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage. Nature. 400: 81-3. PMID 10403253 DOI: 10.1038/21913 |
0.445 |
|
| 1999 |
Stommel JM, Marchenko ND, Jimenez GS, Moll UM, Hope TJ, Wahl GM. A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking. The Embo Journal. 18: 1660-72. PMID 10075936 DOI: 10.1093/Emboj/18.6.1660 |
0.746 |
|
| 1999 |
Jiang XR, Jimenez G, Chang E, Frolkis M, Kusler B, Sage M, Beeche M, Bodnar AG, Wahl GM, Tlsty TD, Chiu CP. Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype. Nature Genetics. 21: 111-4. PMID 9916802 DOI: 10.1038/5056 |
0.367 |
|
| 1998 |
Jiang W, Jimenez G, Wells NJ, Hope TJ, Wahl GM, Hunter T, Fukunaga R. PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis. Molecular Cell. 2: 877-85. PMID 9885575 DOI: 10.1016/S1097-2765(00)80302-0 |
0.347 |
|
| 1998 |
Aladjem MI, Rodewald LW, Kolman JL, Wahl GM. Genetic dissection of a mammalian replicator in the human beta-globin locus. Science (New York, N.Y.). 281: 1005-9. PMID 9703500 DOI: 10.1126/Science.281.5379.1005 |
0.375 |
|
| 1998 |
Paulson TG, Almasan A, Brody LL, Wahl GM. Gene amplification in a p53-deficient cell line requires cell cycle progression under conditions that generate DNA breakage. Molecular and Cellular Biology. 18: 3089-100. PMID 9566927 DOI: 10.1128/Mcb.18.5.3089 |
0.705 |
|
| 1998 |
Kanda T, Sullivan KF, Wahl GM. Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells. Current Biology : Cb. 8: 377-85. PMID 9545195 DOI: 10.1016/S0960-9822(98)70156-3 |
0.393 |
|
| 1998 |
Shimizu N, Itoh N, Utiyama H, Wahl GM. Selective entrapment of extrachromosomally amplified DNA by nuclear budding and micronucleation during S phase. The Journal of Cell Biology. 140: 1307-20. PMID 9508765 DOI: 10.1083/Jcb.140.6.1307 |
0.411 |
|
| 1998 |
Aladjem MI, Spike BT, Rodewald LW, Hope TJ, Klemm M, Jaenisch R, Wahl GM. ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage. Current Biology : Cb. 8: 145-55. PMID 9443911 DOI: 10.1016/S0960-9822(98)70061-2 |
0.487 |
|
| 1998 |
Aladjem MI, Wahl GM. Mapping replication fork direction by leading strand analysis. Methods (San Diego, Calif.). 13: 281-92. PMID 9441854 DOI: 10.1006/Meth.1997.0527 |
0.36 |
|
| 1997 |
Aladjem MI, Brody LL, O'Gorman S, Wahl GM. Positive selection of FLP-mediated unequal sister chromatid exchange products in mammalian cells. Molecular and Cellular Biology. 17: 857-61. PMID 9001240 DOI: 10.1128/Mcb.17.2.857 |
0.345 |
|
| 1996 |
Jones SN, Sands AT, Hancock AR, Vogel H, Donehower LA, Linke SP, Wahl GM, Bradley A. The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2 Proceedings of the National Academy of Sciences of the United States of America. 93: 14106-14111. PMID 8943068 DOI: 10.1073/Pnas.93.24.14106 |
0.444 |
|
| 1996 |
Huang LC, Clarkin KC, Wahl GM. Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest. Proceedings of the National Academy of Sciences of the United States of America. 93: 4827-32. PMID 8643488 DOI: 10.1073/Pnas.93.10.4827 |
0.414 |
|
| 1996 |
Linke SP, Clarkin KC, Di Leonardo A, Tsou A, Wahl GM. A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage. Genes & Development. 10: 934-47. PMID 8608941 DOI: 10.1101/Gad.10.8.934 |
0.422 |
|
| 1996 |
Shimizu N, Kanda T, Wahl GM. Selective capture of acentric fragments by micronuclei provides a rapid method for purifying extrachromosomally amplified DNA. Nature Genetics. 12: 65-71. PMID 8528254 DOI: 10.1038/Ng0196-65 |
0.395 |
|
| 1995 |
Almasan A, Yin Y, Kelly RE, Lee EY, Bradley A, Li W, Bertino JR, Wahl GM. Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 92: 5436-40. PMID 7777526 DOI: 10.1073/Pnas.92.12.5436 |
0.67 |
|
| 1995 |
Kelly RE, DeRose ML, Draper BW, Wahl GM. Identification of an origin of bidirectional DNA replication in the ubiquitously expressed mammalian CAD gene. Molecular and Cellular Biology. 15: 4136-48. PMID 7623808 DOI: 10.1128/Mcb.15.8.4136 |
0.43 |
|
| 1995 |
Almasan A, Linke SP, Paulson TG, Huang LC, Wahl GM. Genetic instability as a consequence of inappropriate entry into and progression through S-phase. Cancer Metastasis Reviews. 14: 59-73. PMID 7606822 DOI: 10.1007/Bf00690212 |
0.692 |
|
| 1995 |
Aladjem MI, Groudine M, Brody LL, Dieken ES, Fournier RE, Wahl GM, Epner EM. Participation of the human beta-globin locus control region in initiation of DNA replication. Science (New York, N.Y.). 270: 815-9. PMID 7481774 DOI: 10.1126/Science.270.5237.815 |
0.354 |
|
| 1995 |
Li W, Fan J, Hochhauser D, Banerjee D, Zielinski Z, Almasan A, Yin Y, Kelly R, Wahl GM, Bertino JR. Lack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines. Proceedings of the National Academy of Sciences of the United States of America. 92: 10436-40. PMID 7479800 DOI: 10.1073/Pnas.92.22.10436 |
0.656 |
|
| 1994 |
Almasan A, Mangelsdorf DJ, Ong ES, Wahl GM, Evans RM. Chromosomal localization of the human retinoid X receptors. Genomics. 20: 397-403. PMID 8034312 DOI: 10.1006/Geno.1994.1193 |
0.613 |
|
| 1994 |
Eckhardt SG, Dai A, Davidson KK, Forseth BJ, Wahl GM, Von Hoff DD. Induction of differentiation in HL60 cells by the reduction of extrachromosomally amplified c-myc. Proceedings of the National Academy of Sciences of the United States of America. 91: 6674-8. PMID 8022834 DOI: 10.1073/Pnas.91.14.6674 |
0.391 |
|
| 1994 |
Di Leonardo A, Linke SP, Clarkin K, Wahl GM. DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts. Genes & Development. 8: 2540-51. PMID 7958916 DOI: 10.1101/Gad.8.21.2540 |
0.439 |
|
| 1993 |
Nonet GH, Wahl GM. Introduction of YACs containing a putative mammalian replication origin into mammalian cells can generate structures that replicate autonomously. Somatic Cell and Molecular Genetics. 19: 171-92. PMID 8511674 DOI: 10.1007/Bf01233532 |
0.417 |
|
| 1993 |
Carroll SM, DeRose ML, Kolman JL, Nonet GH, Kelly RE, Wahl GM. Localization of a bidirectional DNA replication origin in the native locus and in episomally amplified murine adenosine deaminase loci. Molecular and Cellular Biology. 13: 2971-81. PMID 8474455 DOI: 10.1128/Mcb.13.5.2971 |
0.39 |
|
| 1993 |
Nonet GH, Carroll SM, DeRose ML, Wahl GM. Molecular dissection of an extrachromosomal amplicon reveals a circular structure consisting of an imperfect inverted duplication. Genomics. 15: 543-58. PMID 8468049 DOI: 10.1006/Geno.1993.1107 |
0.366 |
|
| 1993 |
Barclay BJ, Ondrusek NK, Wildenhain YD, Huang T, Carlone RL, Clement JM, Wahl GM. Effect of genomic position on amplification of the DFR1 gene in Saccharomyces cerevisiae Advances in Experimental Medicine and Biology. 338: 545-550. PMID 8304177 DOI: 10.1007/978-1-4615-2960-6_111 |
0.396 |
|
| 1993 |
Di Leonardo A, Linke SP, Yin Y, Wahl GM. Cell cycle regulation of gene amplification. Cold Spring Harbor Symposia On Quantitative Biology. 58: 655-67. PMID 7956082 DOI: 10.1101/Sqb.1993.058.01.073 |
0.383 |
|
| 1992 |
Yin Y, Tainsky MA, Bischoff FZ, Strong LC, Wahl GM. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles Cell. 70: 937-948. PMID 1525830 DOI: 10.1016/0092-8674(92)90244-7 |
0.456 |
|
| 1992 |
Von Hoff DD, McGill JR, Forseth BJ, Davidson KK, Bradley TP, Van Devanter DR, Wahl GM. Elimination of extrachromosomally amplified MYC genes from human tumor cells reduces their tumorigenicity. Proceedings of the National Academy of Sciences of the United States of America. 89: 8165-9. PMID 1518843 DOI: 10.1073/Pnas.89.17.8165 |
0.394 |
|
| 1992 |
Kimmel M, Axelrod DE, Wahl GM. A branching process model of gene amplification following chromosome breakage. Mutation Research. 276: 225-39. PMID 1374516 DOI: 10.1016/0165-1110(92)90010-7 |
0.395 |
|
| 1991 |
Windle B, Draper BW, Yin YX, O'Gorman S, Wahl GM. A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration. Genes & Development. 5: 160-74. PMID 1995414 DOI: 10.1101/Gad.5.2.160 |
0.395 |
|
| 1991 |
O'Gorman S, Fox DT, Wahl GM. Recombinase-mediated gene activation and site-specific integration in mammalian cells. Science (New York, N.Y.). 251: 1351-5. PMID 1900642 DOI: 10.1126/Science.1900642 |
0.412 |
|
| 1991 |
Carroll SM, Trotter J, Wahl GM. Replication timing control can be maintained in extrachromosomally amplified genes. Molecular and Cellular Biology. 11: 4779-85. PMID 1678857 DOI: 10.1128/Mcb.11.9.4779 |
0.386 |
|
| 1990 |
Ruiz JC, Wahl GM. Chromosomal destabilization during gene amplification. Molecular and Cellular Biology. 10: 3056-66. PMID 2188107 DOI: 10.1128/Mcb.10.6.3056 |
0.378 |
|
| 1989 |
Stark GR, Debatisse M, Giulotto E, Wahl GM. Recent progress in understanding mechanisms of mammalian DNA amplification Cell. 57: 901-908. PMID 2661014 DOI: 10.1016/0092-8674(89)90328-0 |
0.526 |
|
| 1989 |
Ruiz JC, Choi KH, von Hoff DD, Roninson IB, Wahl GM. Autonomously replicating episomes contain mdr1 genes in a multidrug-resistant human cell line. Molecular and Cellular Biology. 9: 109-15. PMID 2648129 DOI: 10.1128/Mcb.9.1.109 |
0.409 |
|
| 1988 |
Ruiz JC, Wahl GM. Formation of an inverted duplication can be an initial step in gene amplification. Molecular and Cellular Biology. 8: 4302-13. PMID 3185551 DOI: 10.1128/Mcb.8.10.4302 |
0.36 |
|
| 1988 |
Von Hoff DD, Needham-VanDevanter DR, Yucel J, Windle BE, Wahl GM. Amplified human MYC oncogenes localized to replicating submicroscopic circular DNA molecules. Proceedings of the National Academy of Sciences of the United States of America. 85: 4804-8. PMID 3164477 DOI: 10.1073/Pnas.85.13.4804 |
0.402 |
|
| 1988 |
Carroll SM, DeRose ML, Gaudray P, Moore CM, Needham-Vandevanter DR, Von Hoff DD, Wahl GM. Double minute chromosomes can be produced from precursors derived from a chromosomal deletion. Molecular and Cellular Biology. 8: 1525-33. PMID 2898098 DOI: 10.1128/Mcb.8.4.1525 |
0.336 |
|
| 1988 |
Barclay BJ, Huang T, Nagel MG, Misener VL, Game JC, Wahl GM. Mapping and sequencing of the dihydrofolate reductase gene (DFR1) of Saccharomyces cerevisiae Gene. 63: 175-185. PMID 2838386 DOI: 10.1016/0378-1119(88)90523-9 |
0.329 |
|
| 1987 |
Meinkoth J, Killary AM, Fournier RE, Wahl GM. Unstable and stable CAD gene amplification: importance of flanking sequences and nuclear environment in gene amplification. Molecular and Cellular Biology. 7: 1415-24. PMID 3600632 DOI: 10.1128/Mcb.7.4.1415 |
0.404 |
|
| 1987 |
Wahl GM, Lewis KA, Ruiz JC, Rothenberg B, Zhao J, Evans GA. Cosmid vectors for rapid genomic walking, restriction mapping, and gene transfer. Proceedings of the National Academy of Sciences of the United States of America. 84: 2160-4. PMID 3031668 DOI: 10.1073/Pnas.84.8.2160 |
0.36 |
|
| 1987 |
Carroll SM, Gaudray P, De Rose ML, Emery JF, Meinkoth JL, Nakkim E, Subler M, Von Hoff DD, Wahl GM. Characterization of an episome produced in hamster cells that amplify a transfected CAD gene at high frequency: functional evidence for a mammalian replication origin. Molecular and Cellular Biology. 7: 1740-50. PMID 2885742 DOI: 10.1128/Mcb.7.5.1740 |
0.384 |
|
| 1987 |
Wahl GM, Meinkoth JL, Kimmel AR. Northern and Southern blots. Methods in Enzymology. 152: 572-81. PMID 2443808 DOI: 10.1016/0076-6879(87)52064-X |
0.333 |
|
| 1986 |
Ruiz JC, Wahl GM. Escherichia coli aspartate transcarbamylase: a novel marker for studies of gene amplification and expression in mammalian cells. Molecular and Cellular Biology. 6: 3050-8. PMID 3537729 DOI: 10.1128/Mcb.6.9.3050 |
0.359 |
|
| 1986 |
Meinkoth JL, Legouy E, Brison O, Wahl GM. New RNA species is produced by alternate polyadenylation following rearrangement associated with CAD gene amplification. Somatic Cell and Molecular Genetics. 12: 339-50. PMID 2426798 DOI: 10.1007/Bf01570728 |
0.363 |
|
| 1984 |
Wahl GM, Robert de Saint Vincent B, DeRose ML. Effect of chromosomal position on amplification of transfected genes in animal cells. Nature. 307: 516-20. PMID 6694743 DOI: 10.1038/307516A0 |
0.369 |
|
| 1984 |
Wahl GM, Allen V, Delbruck S, Eckhart W, Meinkoth J, de Saint Vincent BR, Vitto L. Analysis of CAD gene amplification using a combined approach of molecular genetics and cytogenetics. Advances in Experimental Medicine and Biology. 172: 319-45. PMID 6547267 DOI: 10.1007/978-1-4615-9376-8_19 |
0.396 |
|
| 1984 |
Wahl GM, Vitto L, Rubnitz J. Co-amplification of rRNA genes with CAD genes in N-(phosphonacetyl)-L-aspartate-resistant Syrian hamster cells. Molecular and Cellular Biology. 3: 2066-75. PMID 6318080 DOI: 10.1128/Mcb.3.11.2066 |
0.364 |
|
| 1983 |
Redfield DC, Richman DD, Albanil S, Oxman MN, Wahl GM. Detection of herpes simplex virus in clinical specimens by DNA hybridization Diagnostic Microbiology and Infectious Disease. 1: 117-128. PMID 6325080 DOI: 10.1016/0732-8893(83)90041-X |
0.318 |
|
| 1983 |
de Saint Vincent BR, Wahl GM. Homologous recombination in mammalian cells mediates formation of a functional gene from two overlapping gene fragments. Proceedings of the National Academy of Sciences of the United States of America. 80: 2002-6. PMID 6132383 DOI: 10.1073/Pnas.80.7.2002 |
0.407 |
|
| 1982 |
Folger KR, Wong EA, Wahl G, Capecchi MR. Patterns of integration of DNA microinjected into cultured mammalian cells: evidence for homologous recombination between injected plasmid DNA molecules. Molecular and Cellular Biology. 2: 1372-87. PMID 6298598 DOI: 10.1128/Mcb.2.11.1372 |
0.583 |
|
| 1982 |
Wahl GM, Vitto L, Padgett RA, Stark GR. Single-copy and amplified CAD genes in Syrian hamster chromosomes localized by a highly sensitive method for in situ hybridization. Molecular and Cellular Biology. 2: 308-19. PMID 6180304 DOI: 10.1128/mcb.2.3.308-319.1982 |
0.745 |
|
| 1982 |
Padgett RA, Wahl GM, Stark GR. Properties of dispersed, highly repeated DNA within and near the hamster CAD gene. Molecular and Cellular Biology. 2: 302-7. PMID 6180303 DOI: 10.1128/mcb.2.3.302-307.1982 |
0.739 |
|
| 1982 |
Padgett RA, Wahl GM, Stark GR. Structure of the gene for CAD, the multifunctional protein that initiates UMP synthesis in Syrian hamster cells. Molecular and Cellular Biology. 2: 293-301. PMID 6125880 DOI: 10.1128/mcb.2.3.293-301.1982 |
0.752 |
|
| 1981 |
de Saint Vincent BR, Delbrück S, Eckhart W, Meinkoth J, Vitto L, Wahl G. The cloning and reintroduction into animal cells of a functional CAD gene, a dominant amplifiable genetic marker. Cell. 27: 267-77. PMID 6277500 DOI: 10.1016/0092-8674(81)90410-4 |
0.402 |
|
| 1980 |
Alwine JC, Kemp DJ, Parker BA, Reiser J, Renart J, Stark GR, Wahl GM. Detection of specific RNAs or specific fragments of DNA by fractionation in gels and transfer to diazobenzyloxymethyl paper. Methods in Enzymology. 68: 220-42. PMID 94421 DOI: 10.1016/0076-6879(79)68017-5 |
0.505 |
|
| 1979 |
Wahl GM, Stern M, Stark GR. Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate. Proceedings of the National Academy of Sciences of the United States of America. 76: 3683-7. PMID 291033 DOI: 10.1073/Pnas.76.8.3683 |
0.526 |
|
| 1975 |
Capecchi MR, Hughes SH, Wahl GM. Yeast super-suppressors are altered tRNAs capable of translating a nonsense codon in vitro. Cell. 6: 269-77. PMID 802681 DOI: 10.1016/0092-8674(75)90178-6 |
0.55 |
|
| 1975 |
Wahl GM, Hughes SH, Capecchi MR. Immunological characterization of hypoxanthine-guanine phosphoribosyl transferase mutants of mouse L cells: evidence for mutations at different loci in the HGPRT gene. Journal of Cellular Physiology. 85: 307-20. PMID 47331 DOI: 10.1002/Jcp.1040850217 |
0.572 |
|
| 1974 |
Capecchi MR, Capecchi NE, Hughes SH, Wahl GM. Selective degradation of abnormal proteins in mammalian tissue culture cells. Proceedings of the National Academy of Sciences of the United States of America. 71: 4732-6. PMID 4531013 DOI: 10.1073/Pnas.71.12.4732 |
0.551 |
|
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