Hartmut Land - Publications

Affiliations: 
University of Rochester, Rochester, NY 
Area:
Genetics, Oncology, Cell Biology

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 McMurray HR, Ambeskovic A, Newman LA, Aldersley J, Balakrishnan V, Smith B, Stern HA, Land H, McCall MN. Gene network modeling via TopNet reveals functional dependencies between diverse tumor-critical mediator genes. Cell Reports. 37: 110136. PMID 34936873 DOI: 10.1016/j.celrep.2021.110136  0.362
2016 Komisarof J, McCall M, Newman L, Bshara W, Mohler JL, Morrison C, Land H. A four gene signature predictive of recurrent prostate cancer. Oncotarget. PMID 27966447 DOI: 10.18632/Oncotarget.13837  0.308
2016 Smith B, Schafer XL, Ambeskovic A, Spencer CM, Land H, Munger J. Addiction to Coupling of the Warburg Effect with Glutamine Catabolism in Cancer Cells. Cell Reports. 17: 821-836. PMID 27732857 DOI: 10.1016/J.Celrep.2016.09.045  0.405
2015 Pulvino M, Chen L, Oleksyn D, Li J, Compitello G, Rossi R, Spence S, Balakrishnan V, Jordan C, Poligone B, Casulo C, Burack R, Shapiro JL, Bernstein S, Friedberg JW, ... ... Land H, et al. Inhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline. Oncotarget. 6: 14796-813. PMID 26142707 DOI: 10.18632/Oncotarget.4193  0.339
2015 Balakrishnan V, Conan K, O'Dell M, Huang JL, Newman L, Whitney-Miller C, Land H, Hezel A. Abstract PR09: Plac8 links oncogenic mutations to regulation of autophagy and is critical to pancreatic cancer progression Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-Pr09  0.48
2014 Kinsey C, Balakrishnan V, O'Dell MR, Huang JL, Newman L, Whitney-Miller CL, Hezel AF, Land H. Plac8 links oncogenic mutations to regulation of autophagy and is critical to pancreatic cancer progression. Cell Reports. 7: 1143-55. PMID 24794439 DOI: 10.1016/J.Celrep.2014.03.061  0.691
2013 Hu X, Dutta P, Tsurumi A, Li J, Wang J, Land H, Li WX. Unphosphorylated STAT5A stabilizes heterochromatin and suppresses tumor growth. Proceedings of the National Academy of Sciences of the United States of America. 110: 10213-8. PMID 23733954 DOI: 10.1073/Pnas.1221243110  0.433
2013 Gaur K, Li J, Wang D, Dutta P, Yan SJ, Tsurumi A, Land H, Wu G, Li WX. The Birt-Hogg-Dubé tumor suppressor Folliculin negatively regulates ribosomal RNA synthesis. Human Molecular Genetics. 22: 284-99. PMID 23077212 DOI: 10.1093/Hmg/Dds428  0.399
2013 Sampson ER, McMurray HR, Hassane DC, Newman L, Salzman P, Jordan CT, Land H. Gene signature critical to cancer phenotype as a paradigm for anticancer drug discovery. Oncogene. 32: 3809-18. PMID 22964631 DOI: 10.1038/Onc.2012.389  0.451
2012 Smith B, Land H. Anticancer activity of the cholesterol exporter ABCA1 gene. Cell Reports. 2: 580-90. PMID 22981231 DOI: 10.1016/J.Celrep.2012.08.011  0.386
2012 Ashton JM, Balys M, Neering SJ, Hassane DC, Cowley G, Root DE, Miller PG, Ebert BL, McMurray HR, Land H, Jordan CT. Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells. Cell Stem Cell. 11: 359-72. PMID 22863534 DOI: 10.1016/J.Stem.2012.05.024  0.435
2012 O'Dell MR, Huang JL, Whitney-Miller CL, Deshpande V, Rothberg P, Grose V, Rossi RM, Zhu AX, Land H, Bardeesy N, Hezel AF. Kras(G12D) and p53 mutation cause primary intrahepatic cholangiocarcinoma. Cancer Research. 72: 1557-67. PMID 22266220 DOI: 10.1158/0008-5472.Can-11-3596  0.392
2011 Almudevar A, McCall MN, McMurray H, Land H. Fitting Boolean networks from steady state perturbation data. Statistical Applications in Genetics and Molecular Biology. 10. PMID 23089817 DOI: 10.2202/1544-6115.1727  0.3
2011 Ashton JM, Balys M, Neering S, Cowley G, Root DE, Miller PG, Ebert B, McMurray H, Hassane DC, Land H, Jordan CT. Oncogene Cooperativity Analysis Reveals a Novel Set of Genes That Regulate the In Vivo Growth and Survival of Leukemia Stem Cells Blood. 118: 553-553. DOI: 10.1182/Blood.V118.21.553.553  0.463
2011 Schafer X, Smith B, Spencer C, Land H, Munger JC. Abstract 1249: Metabolomic analysis of a genetically defined model of oncogenesis reveals that common oncogenic mutations result in synergistic deregulation of multiple metabolic pathways Cancer Research. 71: 1249-1249. DOI: 10.1158/1538-7445.Am2011-1249  0.396
2008 McMurray HR, Sampson ER, Compitello G, Kinsey C, Newman L, Smith B, Chen SR, Klebanov L, Salzman P, Yakovlev A, Land H. Synergistic response to oncogenic mutations defines gene class critical to cancer phenotype. Nature. 453: 1112-6. PMID 18500333 DOI: 10.1038/Nature06973  0.699
2007 Xia M, Land H. Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility. Nature Structural & Molecular Biology. 14: 215-23. PMID 17310253 DOI: 10.1038/Nsmb1208  0.424
2001 Deleu L, Shellard S, Alevizopoulos K, Amati B, Land H. Recruitment of TRRAP required for oncogenic transformation by E1A Oncogene. 20: 8270-8275. PMID 11781841 DOI: 10.1038/Sj.Onc.1205159  0.36
2001 Roper E, Weinberg W, Watt FM, Land H. P19ARF - Independent induction of p53 and cell cycle arrest by Raf in murine keratinocytes Embo Reports. 2: 145-150. PMID 11258707 DOI: 10.1093/Embo-Reports/Kve020  0.414
1997 Sewing A, Wiseman B, Lloyd AC, Land H. High-intensity Raf signal causes cell cycle arrest mediated by p21(Cip1) Molecular and Cellular Biology. 17: 5588-5597. PMID 9271434 DOI: 10.1128/Mcb.17.9.5588  0.405
1997 Pérez-Roger I, Solomon DL, Sewing A, Land H. Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27(Kip1) binding to newly formed complexes. Oncogene. 14: 2373-2381. PMID 9188852 DOI: 10.1038/Sj.Onc.1201197  0.331
1997 Lloyd AC, Obermüller F, Staddon S, Barth CF, McMahon M, Land H. Cooperating oncogenes converge to regulate cyclin/cdk complexes. Genes & Development. 11: 663-77. PMID 9119230 DOI: 10.1101/Gad.11.5.663  0.38
1995 Land H. [3] Transformation of primary rat embryo cells Methods in Enzymology. 254: 37-41. PMID 8531699 DOI: 10.1016/0076-6879(95)54005-9  0.428
1994 Amati B, Land H. Myc-Max-Mad: a transcription factor network controlling cell cycle progression, differentiation and death. Current Opinion in Genetics & Development. 4: 102-108. PMID 8193530 DOI: 10.1016/0959-437X(94)90098-1  0.361
1994 Evan G, Harrington E, Fanidi A, Land H, Amati B, Bennett M. Integrated control of cell proliferation and cell death by the c-myc oncogene. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 345: 269-75. PMID 7846125 DOI: 10.1098/Rstb.1994.0105  0.4
1993 Amati B, Brooks MW, Levy N, Littlewood TD, Evan GI, Land H. Oncogenic activity of the c-Myc protein requires dimerization with Max. Cell. 72: 233-45. PMID 8425220 DOI: 10.1016/0092-8674(93)90663-B  0.371
1993 Amati B, Littlewood TD, Evan GI, Land H. The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max. The Embo Journal. 12: 5083-5087. DOI: 10.1002/J.1460-2075.1993.Tb06202.X  0.389
1992 Evan GI, Wyllie AH, Gilbert CS, Littlewood TD, Land H, Brooks M, Waters CM, Penn LZ, Hancock DC. Induction of apoptosis in fibroblasts by c-myc protein Cell. 69: 119-128. PMID 1555236 DOI: 10.1016/0092-8674(92)90123-T  0.341
1992 Amati B, Dalton S, Brooks MW, Littlewood TD, Evan GI, Land H. Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max. Nature. 359: 423-426. PMID 1406955 DOI: 10.1038/359423A0  0.348
1991 Morgenstern JP, Land H. Choice and manipulation of retroviral vectors. Methods of Molecular Biology. 7: 181-206. PMID 21416356 DOI: 10.1385/0-89603-178-0:181  0.342
1990 Penn LJ, Brooks MW, Laufer EM, Littlewood TD, Morgenstern JP, Evan GI, Lee WM, Land H. Domains of human c-myc protein required for autosuppression and cooperation with ras oncogenes are overlapping. Molecular and Cellular Biology. 10: 4961-6. PMID 2201910 DOI: 10.1128/Mcb.10.9.4961  0.368
1990 Morgenstern JP, Land H. Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line Nucleic Acids Research. 18: 3587-3596. PMID 2194165 DOI: 10.1093/Nar/18.12.3587  0.38
1990 Morgenstern JP, Land H. A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cells Nucleic Acids Research. 18: 1068. PMID 2156225 DOI: 10.1093/Nar/18.4.1068  0.361
1990 Penn L, Brooks M, Laufer E, Land H. Negative autoregulation of c-myc transcription. The Embo Journal. 9: 1113-1121. DOI: 10.1002/J.1460-2075.1990.Tb08217.X  0.375
1989 Compere SJ, Baldacci P, Sharpe AH, Thompson T, Land H, Jaenisch R. The ras and myc oncogenes cooperate in tumor induction in many tissues when introduced into midgestation mouse embryos by retroviral vectors Proceedings of the National Academy of Sciences of the United States of America. 86: 2224-2228. PMID 2648394 DOI: 10.1073/Pnas.86.7.2224  0.399
1989 Thompson TC, Southgate J, Land H. Multistage carcinogenesis induced by ras and myc oncogenes in a reconstituted organ Cell. 56: 917-930. PMID 2538247 DOI: 10.1016/0092-8674(89)90625-9  0.406
1988 Ridley AJ, Paterson HF, Noble M, Land H. Ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation. The Embo Journal. 7: 1635-1645. DOI: 10.1002/J.1460-2075.1988.Tb02990.X  0.408
1986 Land H, Chen AC, Morgenstern JP, Parada LF, Weinberg RA. Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts. Molecular and Cellular Biology. 6: 1917-25. PMID 3785184 DOI: 10.1128/Mcb.6.6.1917  0.408
1984 Parada LF, Land H, Weinberg RA, Wolf D, Rotter V. Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation. Nature. 312: 649-51. PMID 6390217 DOI: 10.1038/312649A0  0.444
1984 Lenoir GM, Land H, Parada LF, Cunningham JM, Weinberg RA. Activated oncogenes in Burkitt's lymphoma. Current Topics in Microbiology and Immunology. 113: 6-14. PMID 6090072 DOI: 10.1007/978-3-642-69860-6_2  0.309
1983 Land H, Parada LF, Weinberg RA. Cellular oncogenes and multistep carcinogenesis. Science (New York, N.Y.). 222: 771-8. PMID 6356358 DOI: 10.1126/Science.6356358  0.428
1983 Land H, Parada LF, Weinberg RA. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature. 304: 596-602. PMID 6308472 DOI: 10.1038/304596A0  0.442
1983 Land H, Grez M, Hauser H, Lindenmaier W, Schütz G. [20] Synthesis of ds-cDNA involving addition of dCMP tails to allow cloning of 5′-terminal mRNA sequences Methods in Enzymology. 100: 285-292. PMID 6194405 DOI: 10.1016/0076-6879(83)00062-2  0.325
1980 Lindenmaier W, Nguyen-Huu MC, Stratmann LM, Blin N, Wurtz T, Hauser HJ, Giesecke K, Land H, Jeep S, Grez M, Sippel AE, Schütz G. The isolation and characterization of the chicken lysozyme and ovomucoid gene. Journal of Steroid Biochemistry. 12: 211-8. PMID 6252379 DOI: 10.1016/0022-4731(80)90270-8  0.366
1979 Lindenmaier W, Nguyen-Huu MC, Lurz R, Blin N, Stratmann M, Land H, Jeep S, Sippel AE, Schütz G. Isolation and characterization of the chicken ovomucoid gene Nucleic Acids Research. 7: 1221-1232. PMID 514812 DOI: 10.1093/Nar/7.5.1221  0.316
1979 Nguyen-Huu MC, Stratmann M, Groner B, Wurtz T, Land H, Giesecke K, Sippel AE, Schütz G. Chicken lysozyme gene contains several intervening sequences. Proceedings of the National Academy of Sciences of the United States of America. 76: 76-80. PMID 284375 DOI: 10.1073/Pnas.76.1.76  0.33
1978 Land H, Hofer E, Sekeris CE. Differential behavior of two dexamethasone induced mRNA activities in HTC cells in response to cordycepin and to withdrawal of hormone. Biochemical and Biophysical Research Communications. 83: 607-615. PMID 29627 DOI: 10.1016/0006-291X(78)91033-1  0.312
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