| Year |
Citation |
Score |
| 2011 |
Rawlings JS, Gatzka M, Thomas PG, Ihle JN. Chromatin condensation via the condensin II complex is required for peripheral T-cell quiescence. The Embo Journal. 30: 263-76. PMID 21169989 DOI: 10.1038/Emboj.2010.314 |
0.356 |
|
| 2008 |
Funakoshi-Tago M, Tago K, Kasahara T, Parganas E, Ihle JN. Negative regulation of Jak2 by its auto-phosphorylation at tyrosine 913 via the Epo signaling pathway. Cellular Signalling. 20: 1995-2001. PMID 18682290 DOI: 10.1016/J.Cellsig.2008.07.008 |
0.372 |
|
| 2008 |
Takahashi Y, Takahashi M, Carpino N, Jou ST, Chao JR, Tanaka S, Shigeyoshi Y, Parganas E, Ihle JN. Leukemia inhibitory factor regulates trophoblast giant cell differentiation via Janus kinase 1-signal transducer and activator of transcription 3-suppressor of cytokine signaling 3 pathway. Molecular Endocrinology (Baltimore, Md.). 22: 1673-81. PMID 18451094 DOI: 10.1210/Me.2008-0058 |
0.448 |
|
| 2008 |
Chao JR, Parganas E, Boyd K, Hong CY, Opferman JT, Ihle JN. Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons. Nature. 452: 98-102. PMID 18288109 DOI: 10.1038/Nature06604 |
0.322 |
|
| 2008 |
Funakoshi-Tago M, Pelletier S, Moritake H, Parganas E, Ihle JN. Jak2 FERM domain interaction with the erythropoietin receptor regulates Jak2 kinase activity. Molecular and Cellular Biology. 28: 1792-801. PMID 18160720 DOI: 10.1128/Mcb.01447-07 |
0.395 |
|
| 2007 |
Gingras S, Pelletier S, Boyd K, Ihle JN. Characterization of a family of novel cysteine- serine-rich nuclear proteins (CSRNP). Plos One. 2: e808. PMID 17726538 DOI: 10.1371/Journal.Pone.0000808 |
0.425 |
|
| 2007 |
Ihle JN, Gilliland DG. Jak2: normal function and role in hematopoietic disorders. Current Opinion in Genetics & Development. 17: 8-14. PMID 17208428 DOI: 10.1016/J.Gde.2006.12.009 |
0.396 |
|
| 2006 |
Funakoshi-Tago M, Pelletier S, Matsuda T, Parganas E, Ihle JN. Receptor specific downregulation of cytokine signaling by autophosphorylation in the FERM domain of Jak2. The Embo Journal. 25: 4763-72. PMID 17024180 DOI: 10.1038/Sj.Emboj.7601365 |
0.397 |
|
| 2006 |
Pelletier S, Gingras S, Funakoshi-Tago M, Howell S, Ihle JN. Two domains of the erythropoietin receptor are sufficient for Jak2 binding/activation and function. Molecular and Cellular Biology. 26: 8527-38. PMID 16982687 DOI: 10.1128/Mcb.01035-06 |
0.391 |
|
| 2006 |
Gatzka M, Piekorz R, Moriggl R, Rawlings J, Ihle JN. A role for STAT5A/B in protection of peripheral T-lymphocytes from postactivation apoptosis: insights from gene expression profiling. Cytokine. 34: 143-54. PMID 16757175 DOI: 10.1016/J.Cyto.2006.04.003 |
0.442 |
|
| 2006 |
Takahashi Y, Dominici M, Swift J, Nagy C, Ihle JN. Trophoblast stem cells rescue placental defect in SOCS3-deficient mice. The Journal of Biological Chemistry. 281: 11444-5. PMID 16517610 DOI: 10.1074/Jbc.C600015200 |
0.395 |
|
| 2006 |
Qasimi P, Ming-Lum A, Ghanipour A, Ong CJ, Cox ME, Ihle J, Cacalano N, Yoshimura A, Mui AL. Divergent mechanisms utilized by SOCS3 to mediate interleukin-10 inhibition of tumor necrosis factor alpha and nitric oxide production by macrophages. The Journal of Biological Chemistry. 281: 6316-24. PMID 16352613 DOI: 10.1074/Jbc.M508608200 |
0.369 |
|
| 2006 |
Zhang J, Randall MS, Loyd MR, Li W, Schweers RL, Persons DA, Rehg JE, Noguchi CT, Ihle JN, Ney PA. Role of erythropoietin receptor signaling in Friend virus-induced erythroblastosis and polycythemia. Blood. 107: 73-8. PMID 16174761 DOI: 10.1182/Blood-2005-05-1784 |
0.423 |
|
| 2005 |
Bertolino E, Reddy K, Medina KL, Parganas E, Ihle J, Singh H. Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5. Nature Immunology. 6: 836-43. PMID 16025120 DOI: 10.1038/Ni1226 |
0.336 |
|
| 2005 |
Piekorz RP, Gingras S, Hoffmeyer A, Ihle JN, Weinstein Y. Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase. Molecular Endocrinology (Baltimore, Md.). 19: 431-40. PMID 15471942 DOI: 10.1210/Me.2004-0302 |
0.306 |
|
| 2004 |
Gingras S, Parganas E, de Pauw A, Ihle JN, Murray PJ. Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of toll-like receptor signaling. The Journal of Biological Chemistry. 279: 54702-7. PMID 15491990 DOI: 10.1074/Jbc.M411043200 |
0.365 |
|
| 2004 |
Carpino N, Thierfelder WE, Chang MS, Saris C, Turner SJ, Ziegler SF, Ihle JN. Absence of an essential role for thymic stromal lymphopoietin receptor in murine B-cell development. Molecular and Cellular Biology. 24: 2584-92. PMID 14993294 DOI: 10.1128/MCB.24.6.2584-2592.2004 |
0.345 |
|
| 2004 |
Carpino N, Turner S, Mekala D, Takahashi Y, Zang H, Geiger TL, Doherty P, Ihle JN. Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2. Immunity. 20: 37-46. PMID 14738763 DOI: 10.1016/S1074-7613(03)00351-0 |
0.763 |
|
| 2004 |
Bunting KD, Couldrey C, Moriggl R, Cui Y, Wright H, Wang D, Ryan JJ, Ihle JN, Hennighausen L. Endogenous N-Terminal Truncated STAT5 Expressed from Alternative Start Codons Promotes SCF Signaling in Murine Primary Mast Cell Cultures. Blood. 104: 815-815. DOI: 10.1182/Blood.V104.11.815.815 |
0.456 |
|
| 2003 |
Jeffers JR, Parganas E, Lee Y, Yang C, Wang J, Brennan J, MacLean KH, Han J, Chittenden T, Ihle JN, McKinnon PJ, Cleveland JL, Zambetti GP. Puma is an essential mediator of p53-dependent and -independent apoptotic pathways. Cancer Cell. 4: 321-8. PMID 14585359 DOI: 10.1016/S1535-6108(03)00244-7 |
0.35 |
|
| 2003 |
Lang R, Pauleau AL, Parganas E, Takahashi Y, Mages J, Ihle JN, Rutschman R, Murray PJ. SOCS3 regulates the plasticity of gp130 signaling. Nature Immunology. 4: 546-50. PMID 12754506 DOI: 10.1038/Ni932 |
0.418 |
|
| 2003 |
Sexl V, Kovacic B, Piekorz R, Moriggl R, Stoiber D, Hoffmeyer A, Liebminger R, Kudlacek O, Weisz E, Rothammer K, Ihle JN. Jak1 deficiency leads to enhanced Abelson-induced B-cell tumor formation. Blood. 101: 4937-43. PMID 12576323 DOI: 10.1182/Blood-2001-11-0142 |
0.37 |
|
| 2003 |
Takahashi Y, Carpino N, Cross JC, Torres M, Parganas E, Ihle JN. SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation. The Embo Journal. 22: 372-84. PMID 12554639 DOI: 10.1093/Emboj/Cdg057 |
0.433 |
|
| 2002 |
Jou ST, Carpino N, Takahashi Y, Piekorz R, Chao JR, Carpino N, Wang D, Ihle JN. Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex. Molecular and Cellular Biology. 22: 8580-91. PMID 12446777 DOI: 10.1128/Mcb.22.24.8580-8591.2002 |
0.431 |
|
| 2002 |
Carpino N, Kobayashi R, Zang H, Takahashi Y, Jou ST, Feng J, Nakajima H, Ihle JN. Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein. Molecular and Cellular Biology. 22: 7491-500. PMID 12370296 DOI: 10.1128/Mcb.22.21.7491-7500.2002 |
0.751 |
|
| 2002 |
Baudino TA, McKay C, Pendeville-Samain H, Nilsson JA, Maclean KH, White EL, Davis AC, Ihle JN, Cleveland JL. c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression. Genes & Development. 16: 2530-43. PMID 12368264 DOI: 10.1101/Gad.1024602 |
0.314 |
|
| 2002 |
Zhao S, Zoller K, Masuko M, Rojnuckarin P, Yang XO, Parganas E, Kaushansky K, Ihle JN, Papayannopoulou T, Willerford DM, Clackson T, Blau CA. JAK2, complemented by a second signal from c-kit or flt-3, triggers extensive self-renewal of primary multipotential hemopoietic cells. The Embo Journal. 21: 2159-67. PMID 11980713 DOI: 10.1093/Emboj/21.9.2159 |
0.358 |
|
| 2002 |
Piekorz RP, Hoffmeyer A, Duntsch CD, McKay C, Nakajima H, Sexl V, Snyder L, Rehg J, Ihle JN. The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis. The Embo Journal. 21: 653-64. PMID 11847113 DOI: 10.1093/Emboj/21.4.653 |
0.384 |
|
| 2002 |
Bunting KD, Bradley HL, Hawley TS, Moriggl R, Sorrentino BP, Ihle JN. Reduced lymphomyeloid repopulating activity from adult bone marrow and fetal liver of mice lacking expression of STAT5. Blood. 99: 479-87. PMID 11781228 DOI: 10.1182/Blood.V99.2.479 |
0.444 |
|
| 2002 |
Liao HJ, Kume T, McKay C, Xu MJ, Ihle JN, Carpenter G. Absence of erythrogenesis and vasculogenesis in Plcg1-deficient mice. The Journal of Biological Chemistry. 277: 9335-41. PMID 11744703 DOI: 10.1074/Jbc.M109955200 |
0.327 |
|
| 2001 |
Nakajima H, Brindle PK, Handa M, Ihle JN. Functional interaction of STAT5 and nuclear receptor co-repressor SMRT: implications in negative regulation of STAT5-dependent transcription. The Embo Journal. 20: 6836-44. PMID 11726519 DOI: 10.1093/Emboj/20.23.6836 |
0.393 |
|
| 2001 |
Wang D, Boylin EC, Minegishi Y, Wen R, Smith CI, Ihle JN, Conley ME. Variations in the human phospholipase Cgamma2 gene in patients with B-cell defects of unknown etiology. Immunogenetics. 53: 550-6. PMID 11685467 DOI: 10.1007/S002510100356 |
0.349 |
|
| 2001 |
Otto KG, Broudy VC, Lin NL, Parganas E, Luthi JN, Drachman JG, Ihle JN, Blau CA. Membrane localization is not required for Mpl function in normal hematopoietic cells. Blood. 98: 2077-83. PMID 11567993 DOI: 10.1182/Blood.V98.7.2077 |
0.394 |
|
| 2001 |
Nakajima H, Ihle JN. Granulocyte colony-stimulating factor regulates myeloid differentiation through CCAAT/enhancer-binding protein epsilon. Blood. 98: 897-905. PMID 11493431 DOI: 10.1182/Blood.V98.4.897 |
0.367 |
|
| 2001 |
Ihle J. Pathways in cytokine regulation of hematopoiesis. Annals of the New York Academy of Sciences. 938: 129-30. PMID 11458499 DOI: 10.1111/J.1749-6632.2001.Tb03581.X |
0.311 |
|
| 2001 |
Zang H, Sato K, Nakajima H, McKay C, Ney PA, Ihle JN. The distal region and receptor tyrosines of the Epo receptor are non-essential for in vivo erythropoiesis. The Embo Journal. 20: 3156-66. PMID 11406592 DOI: 10.1093/Emboj/20.12.3156 |
0.756 |
|
| 2001 |
Hoffmeyer A, Piekorz R, Moriggl R, Ihle JN. Gadd45gamma is dispensable for normal mouse development and T-cell proliferation. Molecular and Cellular Biology. 21: 3137-43. PMID 11287618 DOI: 10.1128/Mcb.21.9.3137-3143.2001 |
0.451 |
|
| 2001 |
Ihle JN. The Stat family in cytokine signaling. Current Opinion in Cell Biology. 13: 211-7. PMID 11248555 DOI: 10.1016/S0955-0674(00)00199-X |
0.368 |
|
| 2001 |
Rutschman R, Lang R, Hesse M, Ihle JN, Wynn TA, Murray PJ. Cutting edge: Stat6-dependent substrate depletion regulates nitric oxide production. Journal of Immunology (Baltimore, Md. : 1950). 166: 2173-7. PMID 11160269 DOI: 10.4049/Jimmunol.166.4.2173 |
0.336 |
|
| 2001 |
Wen R, Wang D, McKay C, Bunting KD, Marine JC, Vanin EF, Zambetti GP, Korsmeyer SJ, Ihle JN, Cleveland JL. Jak3 selectively regulates Bax and Bcl-2 expression to promote T-cell development. Molecular and Cellular Biology. 21: 678-89. PMID 11134353 DOI: 10.1128/Mcb.21.2.678-689.2001 |
0.404 |
|
| 2000 |
Diehl S, Anguita J, Hoffmeyer A, Zapton T, Ihle JN, Fikrig E, Rincón M. Inhibition of Th1 differentiation by IL-6 is mediated by SOCS1. Immunity. 13: 805-15. PMID 11163196 DOI: 10.1016/S1074-7613(00)00078-9 |
0.377 |
|
| 2000 |
Schwaller J, Parganas E, Wang D, Cain D, Aster JC, Williams IR, Lee CK, Gerthner R, Kitamura T, Frantsve J, Anastasiadou E, Loh ML, Levy DE, Ihle JN, Gilliland DG. Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2. Molecular Cell. 6: 693-704. PMID 11030348 DOI: 10.1016/S1097-2765(00)00067-8 |
0.344 |
|
| 2000 |
Ihle JN. The challenges of translating knockout phenotypes into gene function. Cell. 102: 131-4. PMID 10943832 DOI: 10.1016/S0092-8674(00)00017-9 |
0.407 |
|
| 2000 |
Wang D, Feng J, Wen R, Marine JC, Sangster MY, Parganas E, Hoffmeyer A, Jackson CW, Cleveland JL, Murray PJ, Ihle JN. Phospholipase Cgamma2 is essential in the functions of B cell and several Fc receptors. Immunity. 13: 25-35. PMID 10933392 DOI: 10.1016/S1074-7613(00)00005-4 |
0.41 |
|
| 2000 |
Wang D, Moriggl R, Stravopodis D, Carpino N, Marine JC, Teglund S, Feng J, Ihle JN. A small amphipathic alpha-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5. The Embo Journal. 19: 392-9. PMID 10654938 DOI: 10.1093/Emboj/19.3.392 |
0.391 |
|
| 2000 |
Sexl V, Piekorz R, Moriggl R, Rohrer J, Brown MP, Bunting KD, Rothammer K, Roussel MF, Ihle JN. Stat5a/b contribute to interleukin 7-induced B-cell precursor expansion, but abl- and bcr/abl-induced transformation are independent of stat5. Blood. 96: 2277-2283. DOI: 10.1182/Blood.V96.6.2277.H8002277_2277_2283 |
0.414 |
|
| 2000 |
Kieslinger M, Woldman I, Moriggl R, Hofmann J, Marine J, Ihle JN, Beug H, Decker T. Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation Genes & Development. 14: 232-244. DOI: 10.1101/Gad.14.2.232 |
0.379 |
|
| 2000 |
Pestina TI, Hutson NK, Parganas E, Moriggl R, Ihle JN, Jackson CW. The antiapoptotic function of megakaryocyte growth and development factor (Peg-rmMGDF) Is disrupted in STAT5ab−/− and JAK2+/− mice Experimental Hematology. 28: 51. DOI: 10.1016/S0301-472X(00)00247-2 |
0.362 |
|
| 1999 |
Marine JC, McKay C, Wang D, Topham DJ, Parganas E, Nakajima H, Pendeville H, Yasukawa H, Sasaki A, Yoshimura A, Ihle JN. SOCS3 is essential in the regulation of fetal liver erythropoiesis. Cell. 98: 617-27. PMID 10490101 DOI: 10.1016/S0092-8674(00)80049-5 |
0.414 |
|
| 1999 |
Marine JC, Topham DJ, McKay C, Wang D, Parganas E, Stravopodis D, Yoshimura A, Ihle JN. SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality. Cell. 98: 609-16. PMID 10490100 DOI: 10.1016/S0092-8674(00)80048-3 |
0.411 |
|
| 1999 |
Moriggl R, Sexl V, Piekorz R, Topham D, Ihle JN. Stat5 activation is uniquely associated with cytokine signaling in peripheral T cells. Immunity. 11: 225-30. PMID 10485657 DOI: 10.1016/S1074-7613(00)80097-7 |
0.459 |
|
| 1999 |
Moriggl R, Topham DJ, Teglund S, Sexl V, McKay C, Wang D, Hoffmeyer A, van Deursen J, Sangster MY, Bunting KD, Grosveld GC, Ihle JN. Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells. Immunity. 10: 249-59. PMID 10072077 DOI: 10.1016/S1074-7613(00)80025-4 |
0.475 |
|
| 1999 |
Yasukawa H, Misawa H, Sakamoto H, Masuhara M, Sasaki A, Wakioka T, Ohtsuka S, Imaizumi T, Matsuda T, Ihle JN, Yoshimura A. The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop. The Embo Journal. 18: 1309-20. PMID 10064597 DOI: 10.1093/Emboj/18.5.1309 |
0.386 |
|
| 1999 |
Brown MP, Nosaka T, Tripp RA, Brooks J, Deursen JMAv, Brenner MK, Doherty PC, Ihle JN. Reconstitution of early lymphoid proliferation and immune function in Jak3-deficient mice by interleukin-3. Blood. 94: 1906-1914. DOI: 10.1182/Blood.V94.6.1906.418K32_1906_1914 |
0.376 |
|
| 1998 |
Packham G, White EL, Eischen CM, Yang H, Parganas E, Ihle JN, Grillot DA, Zambetti GP, Nuñez G, Cleveland JL. Selective regulation of Bcl-XL by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies. Genes & Development. 12: 2475-87. PMID 9716401 DOI: 10.1101/Gad.12.16.2475 |
0.391 |
|
| 1998 |
Teglund S, McKay C, Schuetz E, van Deursen JM, Stravopodis D, Wang D, Brown M, Bodner S, Grosveld G, Ihle JN. Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses. Cell. 93: 841-50. PMID 9630227 DOI: 10.1016/S0092-8674(00)81444-0 |
0.421 |
|
| 1998 |
Parganas E, Wang D, Stravopodis D, Topham DJ, Marine JC, Teglund S, Vanin EF, Bodner S, Colamonici OR, van Deursen JM, Grosveld G, Ihle JN. Jak2 is essential for signaling through a variety of cytokine receptors. Cell. 93: 385-95. PMID 9590173 DOI: 10.1016/S0092-8674(00)81167-8 |
0.446 |
|
| 1998 |
Quelle FW, Wang J, Feng J, Wang D, Cleveland JL, Ihle JN, Zambetti GP. Cytokine rescue of p53-dependent apoptosis and cell cycle arrest is mediated by distinct Jak kinase signaling pathways. Genes & Development. 12: 1099-107. PMID 9553040 DOI: 10.1101/Gad.12.8.1099 |
0.415 |
|
| 1998 |
Bunting KD, Sangster MY, Ihle JN, Sorrentino BP. Restoration of lymphocyte function in Janus kinase 3-deficient mice by retroviral-mediated gene transfer. Nature Medicine. 4: 58-64. PMID 9427607 DOI: 10.1038/Nm0198-058 |
0.408 |
|
| 1998 |
Heydeck D, Thomas L, Schnurr K, Trebus F, Thierfelder WE, Ihle JN, Kühn H. Interleukin-4 and -13 Induce Upregulation of the Murine Macrophage 12/15-Lipoxygenase Activity: Evidence for the Involvement of Transcription Factor STAT6 Blood. 92: 2503-2510. DOI: 10.1182/Blood.V92.7.2503.2503_2503_2510 |
0.392 |
|
| 1997 |
Ihle JN, Nosaka T, Thierfelder W, Quelle FW, Shimoda K. Jaks and Stats in cytokine signaling. Stem Cells (Dayton, Ohio). 15: 105-11; discussion 1. PMID 9368330 DOI: 10.1002/Stem.5530150814 |
0.462 |
|
| 1997 |
Valk PJ, Hol S, Vankan Y, Ihle JN, Askew D, Jenkins NA, Gilbert DJ, Copeland NG, de Both NJ, Löwenberg B, Delwel R. The genes encoding the peripheral cannabinoid receptor and alpha-L-fucosidase are located near a newly identified common virus integration site, Evi11. Journal of Virology. 71: 6796-804. PMID 9261404 DOI: 10.1128/Jvi.71.9.6796-6804.1997 |
0.352 |
|
| 1997 |
Hoyt PR, Bartholomew C, Davis AJ, Yutzey K, Gamer LW, Potter SS, Ihle JN, Mucenski ML. The Evi1 proto-oncogene is required at midgestation for neural, heart, and paraxial mesenchyme development. Mechanisms of Development. 65: 55-70. PMID 9256345 DOI: 10.1016/S0925-4773(97)00057-9 |
0.382 |
|
| 1997 |
Shimoda K, Feng J, Murakami H, Nagata S, Watling D, Rogers NC, Stark GR, Kerr IM, Ihle JN. Jak1 plays an essential role for receptor phosphorylation and Stat activation in response to granulocyte colony-stimulating factor. Blood. 90: 597-604. PMID 9226159 DOI: 10.1182/Blood.V90.2.597 |
0.425 |
|
| 1997 |
Vella A, Teague TK, Ihle J, Kappler J, Marrack P. Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4. The Journal of Experimental Medicine. 186: 325-30. PMID 9221762 DOI: 10.1084/Jem.186.2.325 |
0.407 |
|
| 1997 |
Feng J, Witthuhn BA, Matsuda T, Kohlhuber F, Kerr IM, Ihle JN. Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop. Molecular and Cellular Biology. 17: 2497-501. PMID 9111318 DOI: 10.1128/Mcb.17.5.2497 |
0.387 |
|
| 1997 |
Muthukumaran G, Kotenko S, Donnelly R, Ihle JN, Pestka S. Chimeric erythropoietin-interferon gamma receptors reveal differences in functional architecture of intracellular domains for signal transduction. The Journal of Biological Chemistry. 272: 4993-9. PMID 9030561 DOI: 10.1074/Jbc.272.8.4993 |
0.36 |
|
| 1997 |
Kohlhuber F, Rogers NC, Watling D, Feng J, Guschin D, Briscoe J, Witthuhn BA, Kotenko SV, Pestka S, Stark GR, Ihle JN, Kerr IM. A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses. Molecular and Cellular Biology. 17: 695-706. PMID 9001223 DOI: 10.1128/Mcb.17.2.695 |
0.417 |
|
| 1996 |
Wang D, Stravopodis D, Teglund S, Kitazawa J, Ihle JN. Naturally occurring dominant negative variants of Stat5. Molecular and Cellular Biology. 16: 6141-8. PMID 8887644 DOI: 10.1128/Mcb.16.11.6141 |
0.454 |
|
| 1996 |
Ihle JN. STATs and MAPKs: Obligate or opportunistic partners in signaling Bioessays. 18: 95-98. PMID 8851041 DOI: 10.1002/Bies.950180204 |
0.356 |
|
| 1996 |
Ihle JN. Signaling by the cytokine receptor superfamily in normal and transformed hematopoietic cells Advances in Cancer Research. 68: 23-65. PMID 8712070 DOI: 10.1016/S0065-230X(08)60351-6 |
0.453 |
|
| 1996 |
Thierfelder WE, van Deursen JM, Yamamoto K, Tripp RA, Sarawar SR, Carson RT, Sangster MY, Vignali DA, Doherty PC, Grosveld GC, Ihle JN. Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells. Nature. 382: 171-4. PMID 8700208 DOI: 10.1038/382171A0 |
0.437 |
|
| 1996 |
Kotenko SV, Izotova LS, Pollack BP, Muthukumaran G, Paukku K, Silvennoinen O, Ihle JN, Pestka S. Other kinases can substitute for Jak2 in signal transduction by interferon-gamma. The Journal of Biological Chemistry. 271: 17174-82. PMID 8663414 DOI: 10.1074/Jbc.271.29.17174 |
0.389 |
|
| 1996 |
Quelle FW, Wang D, Nosaka T, Thierfelder WE, Stravopodis D, Weinstein Y, Ihle JN. Erythropoietin induces activation of Stat5 through association with specific tyrosines on the receptor that are not required for a mitogenic response. Molecular and Cellular Biology. 16: 1622-31. PMID 8657137 DOI: 10.1128/Mcb.16.4.1622 |
0.433 |
|
| 1996 |
Ihle JN. Janus kinases in cytokine signalling. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 351: 159-66. PMID 8650262 DOI: 10.1098/Rstb.1996.0012 |
0.431 |
|
| 1996 |
Briscoe J, Rogers NC, Witthuhn BA, Watling D, Harpur AG, Wilks AF, Stark GR, Ihle JN, Kerr IM. Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state. The Embo Journal. 15: 799-809. PMID 8631301 DOI: 10.1002/J.1460-2075.1996.Tb00415.X |
0.422 |
|
| 1996 |
Adachi M, Fischer EH, Ihle J, Imai K, Jirik F, Neel B, Pawson T, Shen S, Thomas M, Ullrich A, Zhao Z. Mammalian SH2-containing protein tyrosine phosphatases. Cell. 85: 15. PMID 8620532 DOI: 10.1016/S0092-8674(00)81077-6 |
0.312 |
|
| 1996 |
Ihle JN. STATs: signal transducers and activators of transcription. Cell. 84: 331-4. PMID 8608586 DOI: 10.1016/S0092-8674(00)81277-5 |
0.365 |
|
| 1996 |
Shimoda K, van Deursen J, Sangster MY, Sarawar SR, Carson RT, Tripp RA, Chu C, Quelle FW, Nosaka T, Vignali DA, Doherty PC, Grosveld G, Paul WE, Ihle JN. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature. 380: 630-3. PMID 8602264 DOI: 10.1038/380630A0 |
0.459 |
|
| 1996 |
Kanwar V, Witthuhn B, Campana D, Ihle J. Lack of constitutive activation of Janus kinases and signal transduction and activation of transcription factors in Philadelphia chromosome-positive acute lymphoblastic leukemia [letter] Blood. 87: 4911-4912. DOI: 10.1182/Blood.V87.11.4911.Bloodjournal87114911 |
0.344 |
|
| 1995 |
Ihle JN. The Janus protein tyrosine kinase family and its role in cytokine signaling Advances in Immunology. 60: 1-35. PMID 8607368 DOI: 10.1016/S0065-2776(08)60582-9 |
0.442 |
|
| 1995 |
Copeland NG, Gilbert DJ, Schindler C, Zhong Z, Wen Z, Darnell JE, Mui AL, Miyajima A, Quelle FW, Ihle JN. Distribution of the mammalian Stat gene family in mouse chromosomes. Genomics. 29: 225-8. PMID 8530075 DOI: 10.1006/Geno.1995.1235 |
0.32 |
|
| 1995 |
Ihle JN. The Janus protein tyrosine kinases in hematopoietic cytokine signaling Seminars in Immunology. 7: 247-254. PMID 8520029 DOI: 10.1006/Smim.1995.0029 |
0.434 |
|
| 1995 |
Ihle JN, Kerr IM. Jaks and Stats in signaling by the cytokine receptor superfamily Trends in Genetics. 11: 69-74. PMID 7716810 DOI: 10.1016/S0168-9525(00)89000-9 |
0.413 |
|
| 1995 |
Kotenko SV, Izotova LS, Pollack BP, Mariano TM, Donnelly RJ, Muthukumaran G, Cook JR, Garotta G, Silvennoinen O, Ihle JN. Interaction between the components of the interferon gamma receptor complex. The Journal of Biological Chemistry. 270: 20915-21. PMID 7673114 DOI: 10.1074/Jbc.270.36.20915 |
0.355 |
|
| 1995 |
Quelle FW, Thierfelder W, Witthuhn BA, Tang B, Cohen S, Ihle JN. Phosphorylation and activation of the DNA binding activity of purified stat1 by the Janus protein-tyrosine kinases and the epidermal growth factor receptor Journal of Biological Chemistry. 270: 20775-20780. PMID 7657660 DOI: 10.1074/Jbc.270.35.20775 |
0.409 |
|
| 1995 |
Ihle JN, Witthuhn BA, Quelle FW, Yamamoto K, Silvennoinen O. Signaling through the hematopoietic cytokine receptors Annual Review of Immunology. 13: 369-398. PMID 7612228 DOI: 10.1146/Annurev.Iy.13.040195.002101 |
0.414 |
|
| 1995 |
Kawahara A, Minami Y, Miyazaki T, Ihle JN, Taniguchi T. Critical role of the interleukin 2 (IL-2) receptor γ-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction Proceedings of the National Academy of Sciences of the United States of America. 92: 8724-8728. PMID 7568005 DOI: 10.1073/Pnas.92.19.8724 |
0.374 |
|
| 1995 |
Ihle JN. Cytokine receptor signalling Nature. 377: 591-594. PMID 7566171 DOI: 10.1038/377591A0 |
0.413 |
|
| 1995 |
Lai KS, Jin Y, Graham DK, Witthuhn BA, Ihle JN, Liu ET. A kinase-deficient splice variant of the human JAK3 is expressed in hematopoietic and epithelial cancer cells. The Journal of Biological Chemistry. 270: 25028-36. PMID 7559633 DOI: 10.1074/Jbc.270.42.25028 |
0.452 |
|
| 1995 |
Pernis A, Witthuhn B, Keegan AD, Nelms K, Garfein E, Ihle JN, Paul WE, Pierce JH, Rothman P. Interleukin 4 signals through two related pathways. Proceedings of the National Academy of Sciences of the United States of America. 92: 7971-5. PMID 7544011 DOI: 10.1073/Pnas.92.17.7971 |
0.377 |
|
| 1995 |
Ofir R, Novick I, Krup M, Cleveland JL, Ihle JN, Weinstein Y. Structural and functional analysis of the promoter of the murine V gamma 1.1 T cell receptor gene. European Journal of Immunology. 25: 3070-8. PMID 7489745 DOI: 10.1002/Eji.1830251113 |
0.421 |
|
| 1995 |
Nosaka T, Van Deursen JMA, Tripp RA, Thierfelder WE, Witthuhn BA, McMickle AP, Doherty PC, Grosveld GC, Ihle JN. Defective lymphoid development in mice lacking Jak3 Science. 270: 800-802. PMID 7481769 DOI: 10.1126/Science.270.5237.800 |
0.46 |
|
| 1995 |
Sandoval C, Parganas E, Wang W, Ihle JN, Adams-Graves P. Lack of alterations in the cytoplasmic domains of the granulocyte colony-stimulating factor receptors in eight cases of severe congenital neutropenia [letter] Blood. 85: 852-853. DOI: 10.1182/Blood.V85.3.852.Bloodjournal853852 |
0.303 |
|
| 1994 |
Stahl N, Boulton TG, Farruggella T, Ip NY, Davis S, Witthuhn BA, Quelle FW, Silvennoinen O, Barbieri G, Pellegrini S, Ihle JN, Yancopoulos GD. Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 β receptor components Science. 263: 92-95. PMID 8272873 DOI: 10.1126/Science.8272873 |
0.38 |
|
| 1994 |
Narazaki M, Witthuhn BA, Yoshida K, Silvennoinen O, Yasukawa K, Ihle JN, Kishimoto T, Taga T. Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130 Proceedings of the National Academy of Sciences of the United States of America. 91: 2285-2289. PMID 8134389 DOI: 10.1073/Pnas.91.6.2285 |
0.421 |
|
| 1994 |
Ihle JN, Witthuhn BA, Quelle FW, Yamamoto K, Thierfelder WE, Kreider B, Silvennoinen O. Signaling by the cytokine receptor superfamily: JAKs and STATs Trends in Biochemical Sciences. 19: 222-227. PMID 8048164 DOI: 10.1016/0968-0004(94)90026-4 |
0.408 |
|
| 1994 |
Brenner MK, Rill DR, Moen RC, Krance RA, Heslop HE, Mirro J, Anderson WF, Ihle JN, Huber BE. Gene marking and autologous bone marrow transplantation Annals of the New York Academy of Sciences. 716: 204-215. PMID 8024195 DOI: 10.1111/J.1749-6632.1994.Tb21713.X |
0.304 |
|
| 1994 |
Witthuhn BA, Silvennoinen O, Miura O, Lai KS, Cwik C, Liu ET, Ihle JN. Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells Nature. 370: 153-157. PMID 8022486 DOI: 10.1038/370153A0 |
0.43 |
|
| 1994 |
Yamamoto K, Quelle FW, Thierfelder WE, Kreider BL, Gilbert DJ, Jenkins NA, Copeland NG, Silvennoinen O, Ihle JN. Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation Molecular and Cellular Biology. 14: 4342-4349. PMID 8007943 DOI: 10.1128/Mcb.14.7.4342 |
0.456 |
|
| 1994 |
Quelle FW, Sato N, Witthuhn BA, Inhorn RC, Eder M, Miyajima A, Griffin JD, Ihle JN. JAK2 associates with the βc chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region Molecular and Cellular Biology. 14: 4335-4341. PMID 8007942 DOI: 10.1128/Mcb.14.7.4335 |
0.418 |
|
| 1994 |
Rothman P, Kreider B, Azam M, Levy D, Wegenka U, Eilers A, Decker T, Horn F, Kashleva H, Ihle J, Schindler C. Cytokines and Growth factors signal through tyrosine phosphorylation of a family of related transcription factors Immunity. 1: 457-468. PMID 7895157 DOI: 10.1016/1074-7613(94)90088-4 |
0.413 |
|
| 1994 |
Tang B, Mano H, Yi T, Ihle JN. Tec kinase associates with c-kit and is tyrosine phosphorylated and activated following stem cell factor binding Molecular and Cellular Biology. 14: 8432-8437. PMID 7526158 DOI: 10.1128/mcb.14.12.8432-8437.1994 |
0.42 |
|
| 1994 |
Ihle JN, Witthuhn B, Tang B, Yi T, Quelle FW. 2 Cytokine receptors and signal transduction Bailliere's Clinical Haematology. 7: 17-48. PMID 7518712 DOI: 10.1016/S0950-3536(05)80005-8 |
0.39 |
|
| 1994 |
Ihle JN. The Janus Kinase Family and Signaling Through Members of the Cytokine Receptor Superfamily Proceedings of the Society For Experimental Biology and Medicine. 206: 268-272. PMID 7517047 DOI: 10.3181/00379727-206-43757 |
0.4 |
|
| 1994 |
Carter-Su C, Argetsinger LS, Campbell GS, Wang X, Ihle J, Witthuhn B. The identification of JAK2 tyrosine kinase as a signaling molecule for growth hormone Proceedings of the Society For Experimental Biology and Medicine. 206: 210-215. PMID 7517045 DOI: 10.3181/00379727-206-43744 |
0.367 |
|
| 1994 |
Campbell GS, Argetsinger LS, Ihle JN, Kelly PA, Rillema JA, Carter-Su C. Activation of JAK2 tyrosine kinase by prolactin receptors in Nb2 cells and mouse mammary gland explants Proceedings of the National Academy of Sciences of the United States of America. 91: 5232-5236. PMID 7515493 DOI: 10.1073/Pnas.91.12.5232 |
0.43 |
|
| 1994 |
Ihle JN. Signaling by the cytokine receptor superfamily just another kinase story Trends in Endocrinology and Metabolism. 5: 137-143. DOI: 10.1016/1043-2760(94)90096-5 |
0.396 |
|
| 1994 |
Beadling C, Guschin D, Witthuhn BA, Ziemiecki A, Ihle JN, Kerr IM, Cantrell DA. Activation of JAK kinases and STAT proteins by interleukin-2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes. The Embo Journal. 13: 5605-5615. DOI: 10.1002/J.1460-2075.1994.Tb06898.X |
0.436 |
|
| 1993 |
Miura O, Cleveland JL, Ihle JN. Inactivation of erythropoietin receptor function by point mutations in a region having homology with other cytokine receptors. Molecular and Cellular Biology. 13: 1788-95. PMID 8382775 DOI: 10.1128/Mcb.13.3.1788 |
0.377 |
|
| 1993 |
Silvennoinen O, Witthuhn BA, Quelle FW, Cleveland JL, Yi T, Ihle JN. Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction Proceedings of the National Academy of Sciences of the United States of America. 90: 8429-8433. PMID 8378315 DOI: 10.1073/Pnas.90.18.8429 |
0.417 |
|
| 1993 |
English BK, Ihle JN, Myracle A, Yi T. Hck tyrosine kinase activity modulates tumor necrosis factor production by murine macrophages Journal of Experimental Medicine. 178: 1017-1022. PMID 8350043 DOI: 10.1084/Jem.178.3.1017 |
0.389 |
|
| 1993 |
Argetsinger LS, Campbell GS, Yang X, Witthuhn BA, Silvennoinen O, Ihle JN, Carter-Su C. Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase Cell. 74: 237-244. PMID 8343952 DOI: 10.1016/0092-8674(93)90415-M |
0.364 |
|
| 1993 |
Witthuhn BA, Quelle FW, Silvennoinen O, Yi T, Tang B, Miura O, Ihle JN. JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin Cell. 74: 227-236. PMID 8343951 DOI: 10.1016/0092-8674(93)90414-L |
0.392 |
|
| 1993 |
Shultz LD, Schweitzer PA, Rajan TV, Yi T, Ihle JN, Matthews RJ, Thomas ML, Beier DR. Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene. Cell. 73: 1445-54. PMID 8324828 DOI: 10.1016/0092-8674(93)90369-2 |
0.357 |
|
| 1993 |
Delwel R, Funabiki T, Kreider BL, Morishita K, Ihle JN. Four of the seven zinc fingers of the Evi-1 myeloid-transforming gene are required for sequence-specific binding to GA(C/T)AAGA(T/C)AAGATAA Molecular and Cellular Biology. 13: 4291-4300. PMID 8321231 DOI: 10.1128/Mcb.13.7.4291 |
0.333 |
|
| 1993 |
Ihle JN, Quelle FW, Miura O. Signal transduction through the receptor for erythropoietin Seminars in Immunology. 5: 375-389. PMID 8260653 DOI: 10.1006/Smim.1993.1043 |
0.462 |
|
| 1993 |
Yi T, Mui ALF, Krystal G, Ihle JN. Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor β chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis Molecular and Cellular Biology. 13: 7577-7586. PMID 8246974 DOI: 10.1128/Mcb.13.12.7577 |
0.436 |
|
| 1993 |
Brenner MK, Rill DR, Krance RA, Ihle JN, Moen RC, Mirro J, Anderson WF. Gene-marking to trace origin of relapse after autologous bone-marrow transplantation The Lancet. 341: 85-86. PMID 8093407 DOI: 10.1016/0140-6736(93)92560-G |
0.3 |
|
| 1993 |
Yi T, Ihle JN. Association of hematopoietic cell phosphatase with c-Kit after stimulation with c-Kit ligand Molecular and Cellular Biology. 13: 3350-3358. PMID 7684496 DOI: 10.1128/mcb.13.6.3350-3358.1993 |
0.419 |
|
| 1993 |
Silvennoinen O, Ihle JN, Schlessinger J, Levy DE. Interferon-induced nuclear signalling by Jak protein tyrosine kinases. Nature. 366: 583-5. PMID 7504785 DOI: 10.1038/366583A0 |
0.366 |
|
| 1993 |
Askew D, Ihle J, Cleveland J. Activation of apoptosis associated with enforced myc expression in myeloid progenitor cells is dominant to the suppression of apoptosis by interleukin-3 or erythropoietin Blood. 82: 2079-2087. DOI: 10.1182/Blood.V82.7.2079.2079 |
0.379 |
|
| 1993 |
Miura O, Ihle J. Subunit structure of the erythropoietin receptor analyzed by 125I-Epo cross-linking in cells expressing wild-type or mutant receptors Blood. 81: 1739-1744. DOI: 10.1182/Blood.V81.7.1739.Bloodjournal8171739 |
0.356 |
|
| 1992 |
Yi T, Cleveland JL, Ihle JN. Protein tyrosine phosphatase containing SH2 domains: Characterization, preferential expression in hematopoietic cells, and localization to human chromosome 12p12-p13 Molecular and Cellular Biology. 12: 836-846. PMID 1732748 DOI: 10.1128/mcb.12.2.836-846.1992 |
0.419 |
|
| 1992 |
Ihle JN. Interleukin-3 and hematopoiesis. Chemical Immunology. 51: 65-106. PMID 1567546 DOI: 10.1159/000420755 |
0.369 |
|
| 1992 |
Brenner MK, Furman WL, Santana VM, Bowman L, Meyer W, Crist WM, Campana D, Douglass EC, Ihle J, Boyett J, Hurwitz J, Rao BN, Jenkins JJ, Fletcher B, Kaufman W, et al. Phase I Study of Cytokine-Gene Modified Autologous Neuroblastoma Cells for Treatment of Relapse/Refractory Neuroblastoma Human Gene Therapy. 3: 665-676. PMID 1482707 DOI: 10.1089/Hum.1992.3.6-665 |
0.301 |
|
| 1992 |
Yi T, Gilbert DJ, Jenkins NA, Copeland NG, Ihle JN. Assignment of a novel protein tyrosine phosphatase gene (Hcph) to mouse chromosome 6. Genomics. 14: 793-5. PMID 1427910 DOI: 10.1016/S0888-7543(05)80189-2 |
0.375 |
|
| 1992 |
Morishita K, Parganas E, Matsugi T, Ihle JN. Expression of the Evi-1 zinc finger gene in 32Dc13 myeloid cells blocks granulocytic differentiation in response to granulocyte colony-stimulating factor. Molecular and Cellular Biology. 12: 183-189. PMID 1370341 DOI: 10.1128/Mcb.12.1.183 |
0.385 |
|
| 1992 |
Rill DR, Moen RC, Buschle M, Bartholomew C, Foreman NK, Mirro J, Krance RA, Ihle JN, Brenner M. An approach for the analysis of relapse and marrow reconstitution after autologous marrow transplantation using retrovirus-mediated gene transfer. Blood. 79: 2694-2700. DOI: 10.1182/Blood.V79.10.2694.2694 |
0.334 |
|
| 1991 |
Yi T, Bolen JB, Ihle JN. Hematopoietic cells express two forms of lyn kinase differing by 21 amino acids in the amino terminus Molecular and Cellular Biology. 11: 2391-2398. PMID 2017160 DOI: 10.1128/Mcb.11.5.2391 |
0.405 |
|
| 1991 |
Bartholomew C, Ihle JN. Retroviral insertions 90 kilobases proximal to the Evi-1 myeloid transforming gene activate transcription from the normal promoter. Molecular and Cellular Biology. 11: 1820-1828. PMID 1848663 DOI: 10.1128/Mcb.11.4.1820 |
0.346 |
|
| 1991 |
Miura O, D'Andrea A, Kabat D, Ihle JN. Induction of tyrosine phosphorylation by the erythropoietin receptor correlates with mitogenesis. Molecular and Cellular Biology. 11: 4895-4902. PMID 1656216 DOI: 10.1128/Mcb.11.10.4895 |
0.421 |
|
| 1991 |
Yi T, Cleveland J, Ihle J. Identification of novel protein tyrosine phosphatases of hematopoietic cells by polymerase chain reaction amplification Blood. 78: 2222-2228. DOI: 10.1182/Blood.V78.9.2222.Bloodjournal7892222 |
0.338 |
|
| 1991 |
Ihle JN. The Evi‐1 zinc finger protein and transformation of hematopoietic progenitors Stem Cells. 9: 142-152. DOI: 10.1002/Stem.5530090715 |
0.421 |
|
| 1990 |
Ihle JN, Morishita K, Bartholomew C, Matsugi T, Askew D. Phenotypes and mechanisms in the transformation of hematopoietic cells Stem Cells. 8: 130-146. PMID 2109024 DOI: 10.1002/Stem.5530080712 |
0.437 |
|
| 1990 |
Matsugi T, Morishita K, Ihle JN. Identification, nuclear localization, and DNA-binding activity of the zinc finger protein encoded by the Evi-1 myeloid transforming gene. Molecular and Cellular Biology. 10: 1259-1264. PMID 2106070 DOI: 10.1128/Mcb.10.3.1259 |
0.307 |
|
| 1990 |
Isfort RJ, Ihle JN. Multiple hematopoietic growth factors signal through tyrosine phosphorylation. Growth Factors Journal. 2: 213-220. PMID 1692720 DOI: 10.3109/08977199009071507 |
0.414 |
|
| 1989 |
Cleveland JL, Dean M, Wang JY, Hedge AM, Ihle JN, Rapp UR. Abrogation of IL-3 dependence of myeloid FDC-P1 cells by tyrosine kinase oncogenes is associated with induction of c-myc. Current Topics in Microbiology and Immunology. 141: 300-9. PMID 3265092 DOI: 10.1007/978-3-642-74006-0_40 |
0.357 |
|
| 1989 |
Dean M, Cleveland J, Kim HY, Campisi J, Levine RA, Ihle JN, Rapp U. Deregulation of the c-myc and N-myc genes in transformed cells. Current Topics in Microbiology and Immunology. 141: 216-22. PMID 3215051 DOI: 10.1007/978-3-642-74006-0_29 |
0.344 |
|
| 1989 |
Rapp UR, Heidecker G, Huleihel M, Cleveland JL, Choi WC, Pawson T, Ihle JN, Anderson WB. raf family serine/threonine protein kinases in mitogen signal transduction. Cold Spring Harbor Symposia On Quantitative Biology. 173-84. PMID 2978288 DOI: 10.1101/Sqb.1988.053.01.023 |
0.332 |
|
| 1989 |
Kishi K, Ihle JN, Urdal DL, Ogawa M. Murine B-cell stimulatory factor-1 (BSF-1)/interleukin-4 (IL-4) is a multilineage colony-stimulating factor that acts directly on primitive hemopoietic progenitors. Journal of Cellular Physiology. 139: 463-468. PMID 2786878 DOI: 10.1002/Jcp.1041390303 |
0.361 |
|
| 1989 |
Ihle JN, Askew D. Origins and properties of hematopoietic growth factor‐dependent cell lines Stem Cells. 7: 68-91. PMID 2656885 DOI: 10.1002/Stem.5530070202 |
0.433 |
|
| 1989 |
Weinstein Y, Morishita K, Cleveland JL, Ihle JN. Interleukin 3 (IL-3) induces transcription from nonrearranged T cell receptor gamma loci in IL-3-dependent cell lines. The Journal of Experimental Medicine. 169: 2059-71. PMID 2543731 DOI: 10.1084/Jem.169.6.2059 |
0.395 |
|
| 1989 |
Ihle JN, Smith-White B, Sisson B, Parker D, Blair DG, Schultz A, Kozak C, Lunsford RD, Askew D, Weinstein Y. Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia. Journal of Virology. 63: 2959-66. PMID 2542606 DOI: 10.1128/Jvi.63.7.2959-2966.1989 |
0.301 |
|
| 1989 |
Ihle JN, Morishita K, Parker DS, Bartholomew C, Askew D, Buchberg A, Jenkins NA, Copeland N, Weinstein Y. Mechanisms in the transformation of IL3-dependent hematopoietic stem cells. Current Topics in Microbiology and Immunology. 149: 59-69. PMID 2499442 DOI: 10.1007/978-3-642-74623-9_5 |
0.372 |
|
| 1988 |
Morishita K, Parker DS, Mucenski ML, Jenkins NA, Copeland NG, Ihle JN. Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell lines. Cell. 54: 831-40. PMID 2842066 DOI: 10.1016/S0092-8674(88)91175-0 |
0.422 |
|
| 1988 |
Ikebuchi K, Clark SC, Ihle JN, Souza LM, Ogawa M. Granulocyte colony-stimulating factor enhances interleukin 3-dependent proliferation of multipotential hemopoietic progenitors. Proceedings of the National Academy of Sciences of the United States of America. 85: 3445-3449. PMID 2453060 DOI: 10.1073/Pnas.85.10.3445 |
0.344 |
|
| 1987 |
Ikebuchi K, Wong GG, Clark SC, Ihle JN, Hirai Y, Ogawa M. Interleukin 6 enhancement of interleukin 3-dependent proliferation of multipotential hemopoietic progenitors. Proceedings of the National Academy of Sciences of the United States of America. 84: 9035-9039. PMID 3501121 DOI: 10.1073/Pnas.84.24.9035 |
0.369 |
|
| 1987 |
Ihle JN, Weinstein Y, Rapp UR, Cleveland JL, Reddy EP. Mechanisms in interleukin 3 regulated growth and differentiation. Advances in Experimental Medicine and Biology. 213: 149-62. PMID 3498294 DOI: 10.1007/978-1-4684-5323-2_15 |
0.433 |
|
| 1987 |
Brown MA, Pierce JH, Watson CJ, Falco J, Ihle JN, Paul WE. B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cells. Cell. 50: 809-18. PMID 3497723 DOI: 10.1016/0092-8674(87)90339-4 |
0.399 |
|
| 1987 |
Koike K, Ogawa M, Ihle JN, Miyake T, Shimizu T, Miyajima A, Yokota T, Arai K. Recombinant murine granulocyte-macrophage (GM) colony-stimulating factor supports formation of GM and multipotential blast cell colonies in culture: comparison with the effects of interleukin-3. Journal of Cellular Physiology. 131: 458-64. PMID 3298286 DOI: 10.1002/Jcp.1041310319 |
0.365 |
|
| 1987 |
Weinstein Y, Cleveland JL, Askew DS, Rapp UR, Ihle JN. Insertion and truncation of c-myb by murine leukemia virus in a myeloid cell line derived from cultures of normal hematopoietic cells. Journal of Virology. 61: 2339-43. PMID 2884332 DOI: 10.1128/Jvi.61.7.2339-2343.1987 |
0.372 |
|
| 1987 |
Brownell E, Mathieson B, Young HA, Keller J, Ihle JN, Rice NR. Detection of c-rel-related transcripts in mouse hematopoietic tissues, fractionated lymphocyte populations, and cell lines. Molecular and Cellular Biology. 7: 1304-9. PMID 2436042 DOI: 10.1128/Mcb.7.3.1304 |
0.357 |
|
| 1986 |
Ihle JN, Weinstein Y. Immunological regulation of hematopoietic/lymphoid stem cell differentiation by interleukin 3. Advances in Immunology. 39: 1-50. PMID 3538818 DOI: 10.1016/S0065-2776(08)60347-8 |
0.45 |
|
| 1986 |
Vistica BP, McAllister CG, Sekura RD, Ihle JN, Gery I. Dual effects of pertussis toxin on lymphoid cells in culture Cellular Immunology. 101: 232-241. PMID 3091265 DOI: 10.1016/0008-8749(86)90200-5 |
0.365 |
|
| 1986 |
Cleveland JL, Jansen HW, Bister K, Fredrickson TN, Morse HC, Ihle JN, Rapp UR. Interaction between Raf and Myc oncogenes in transformation in vivo and in vitro Journal of Cellular Biochemistry. 30: 195-218. PMID 3084503 DOI: 10.1002/Jcb.240300303 |
0.439 |
|
| 1986 |
May WS, Ihle JN. Affinity isolation of the interleukin-3 surface receptor. Biochemical and Biophysical Research Communications. 135: 870-879. PMID 3083813 DOI: 10.1016/0006-291X(86)91009-0 |
0.377 |
|
| 1986 |
Cleveland JL, Weinstein Y, Ihle JN, Askew DS, Rapp UR. Transformation and insertional mutagenesis in vitro of primary hematopoietic stem cell cultures. Current Topics in Microbiology and Immunology. 132: 44-54. PMID 3024923 DOI: 10.1007/978-3-642-71562-4_7 |
0.308 |
|
| 1986 |
Weinstein Y, Ihle JN, Lavu S, Reddy EP. Truncation of the c-myb gene by a retroviral integration in an interleukin 3-dependent myeloid leukemia cell line. Proceedings of the National Academy of Sciences of the United States of America. 83: 5010-4. PMID 3014527 DOI: 10.1073/Pnas.83.14.5010 |
0.395 |
|
| 1986 |
Naparstek E, Pierce J, Metcalf D, Shadduck R, Ihle J, Leder A, Sakakeeny M, Wagner K, Falco J, FitzGerald T. Induction of growth alterations in factor-dependent hematopoietic progenitor cell lines by cocultivation with irradiated bone marrow stromal cell lines. Blood. 67: 1395-1403. DOI: 10.1182/Blood.V67.5.1395.Bloodjournal6751395 |
0.386 |
|
| 1986 |
Suda J, Suda T, Kubota K, Ihle J, Saito M, Miura Y. Purified interleukin-3 and erythropoietin support the terminal differentiation of hemopoietic progenitors in serum-free culture. Blood. 67: 1002-1006. DOI: 10.1182/Blood.V67.4.1002.1002 |
0.387 |
|
| 1985 |
Rapp UR, Bonner TI, Moelling K, Jansen HW, Bister K, Ihle J. Genes and Gene Products Involved in Growth Regulation of Tumor Cells Recent Results in Cancer Research. 99: 221-236. PMID 4070776 DOI: 10.1007/978-3-642-82533-0_24 |
0.325 |
|
| 1985 |
Rapp UR, Cleveland JL, Brightman K, Scott A, Ihle JN. Abrogation of IL-3 and IL-2 dependence by recombinant murine retroviruses expressing v-myc oncogenes. Nature. 317: 434-8. PMID 3930972 DOI: 10.1038/317434A0 |
0.385 |
|
| 1985 |
Suda T, Suda J, Ogawa M, Ihle JN. Permissive role of interleukin 3 (IL-3) in proliferation and differentiation of multipotential hemopoietic progenitors in culture. Journal of Cellular Physiology. 124: 182-190. PMID 3930522 DOI: 10.1002/Jcp.1041240203 |
0.383 |
|
| 1985 |
Rein A, Keller J, Schultz AM, Holmes KL, Medicus R, Ihle JN. Infection of immune mast cells by Harvey sarcoma virus: Immortalization without loss of requirement for interleukin-3 Molecular and Cellular Biology. 5: 2257-2264. PMID 3016524 DOI: 10.1128/Mcb.5.9.2257 |
0.4 |
|
| 1985 |
Holmes KL, Palaszynski E, Fredrickson TN, Morse HC, Ihle JN. Correlation of cell-surface phenotype with the establishment of interleukin 3-dependent cell lines from wild-mouse murine leukemia virus-induced neoplasms. Proceedings of the National Academy of Sciences of the United States of America. 82: 6687-91. PMID 2995979 DOI: 10.1073/Pnas.82.19.6687 |
0.426 |
|
| 1985 |
Pierce JH, Di Fiore PP, Aaronson SA, Potter M, Pumphrey J, Scott A, Ihle JN. Neoplastic transformation of mast cells by Abelson-MuLV: abrogation of IL-3 dependence by a nonautocrine mechanism. Cell. 41: 685-93. PMID 2988783 DOI: 10.1016/S0092-8674(85)80049-0 |
0.386 |
|
| 1985 |
Greenberger JS, Palaszynski EW, Pierce JH, Sakakeeny MA, Ruscetti SK, Ihle JN, Daugherty C. Biologic Effects of Prolonged Melphalan Treatment of Murine Long-Term Bone Marrow Cultures and Interleukin 3-Dependent Hematopoietic Progenitor Cell Lines Journal of the National Cancer Institute. 74: 247-262. DOI: 10.1093/Jnci/74.1.247 |
0.35 |
|
| 1984 |
Weinhold KJ, Hüper G, Matthews TJ, Fischinger PJ, Ihle JN, Schwarz H, Thiel HJ, Schäfer W, Bolognesi DP. Properties of mouse leukemia viruses XIX. Effective antibody therapy of AKR leukemia occurs independently of virus neutralization and produces long-term changes in the virus status of the thymus Virology. 135: 105-117. PMID 6328742 DOI: 10.1016/0042-6822(84)90121-1 |
0.372 |
|
| 1984 |
Ihle JN, Morse HC, Keller J, Holmes KL. Interleukin 3 Dependent Retrovirus Induced Lymphomas: Loss of the Ability to Terminally Differentiate in Response to Differentiation Factors Current Topics in Microbiology and Immunology. 113: 86-91. PMID 6090074 DOI: 10.1007/978-3-642-69860-6_16 |
0.402 |
|
| 1982 |
Ihle JN, Rebar L, Keller J, Lee JC, Hapel AJ. Interleukin 3: Possible Roles in the Regulation of Lymphocyte Differentiation and Growth Immunological Reviews. 63: 5-32. PMID 6804368 DOI: 10.1111/J.1600-065X.1982.Tb00409.X |
0.311 |
|
| 1982 |
Ihle JN, Lee JC. Possible Immunological Mechanisms in C-Type Viral Leukemogenesis in Mice Current Topics in Microbiology and Immunology. 98: 85-101. PMID 6282538 DOI: 10.1007/978-3-642-68369-5_7 |
0.3 |
|
| 1982 |
Fischinger PJ, Dunlop NM, Schwarz H, Ihle JN, Weinhold K, Bolognesi DP, Schäfer W. Properties of mouse leukemia viruses XVIII. Effective treatment of AKR leukemia with antibody to gp7l eliminates the neonatal burst of ecotropic AKR virus producing cells Virology. 119: 68-81. PMID 6280386 DOI: 10.1016/0042-6822(82)90066-6 |
0.341 |
|
| 1982 |
Hapel AJ, Lee JC, Greenberger J, Ihle JN. Characteristics of IL-3 derived and IL-3 dependent lymphocyte cell lines. Advances in Experimental Medicine and Biology. 149: 719-724. PMID 6216774 DOI: 10.1007/978-1-4684-9066-4_99 |
0.411 |
|
| 1982 |
Djeu JY, Lanza E, Hapel AJ, Ihle JN. Natural Cytotoxic Activity Of Mouse Spleen Cell Cultures Maintained With Interleukin-3 Nk Cells and Other Natural Effector Cells. 917-921. DOI: 10.1016/B978-0-12-341360-4.50137-2 |
0.406 |
|
| 1982 |
Fitch F, Prystowsky M, Ely J, Quintans J, Goldwasser E, Goldman J, Goldman M, Beller D, Ihle J, Remold H, Vogel S. Multiple lymphokine activities are secreted by a cloned murine T helper cell Cellular Immunology. 70: 404. DOI: 10.1016/0008-8749(82)90412-9 |
0.363 |
|
| 1981 |
Lee JC, Ihle JN. Increased responses to lymphokines are correlated with preleukemia in mice inoculated with Moloney leukemia virus Proceedings of the National Academy of Sciences of the United States of America. 78: 7712-7716. PMID 6977775 DOI: 10.1073/Pnas.78.12.7712 |
0.327 |
|
| 1981 |
Lee JC, Ihle JN. Chronic immune stimulation is required for Moloney leukaemia virus-induced lymphomas. Nature. 289: 407-409. PMID 6970336 DOI: 10.1038/289407A0 |
0.341 |
|
| 1981 |
Horak I, Enjuanes L, Lee JC, Ihle JN. Resistance of cultures of normal t cells to infection with murine type c viruses. Journal of Virology. 37: 483-487. PMID 6260996 DOI: 10.1128/Jvi.37.1.483-487.1981 |
0.344 |
|
| 1981 |
Fischinger PJ, Thiel HJ, Ihle JN, Lee JC, Elder JH. Detection of a recombinant murine leukemia virus-related glycoprotein on virus-negative thymoma cells Proceedings of the National Academy of Sciences of the United States of America. 78: 1920-1924. PMID 6165021 DOI: 10.1073/Pnas.78.3.1920 |
0.35 |
|
| 1981 |
Hapel AJ, Lee JC, Farrar WL, Ihle JN. Establishment of continuous cultures of Thy1.2+, Lytl+,2−T cells with purified interleukin 3 Cell. 25: 179-186. PMID 6115717 DOI: 10.1016/0092-8674(81)90242-7 |
0.386 |
|
| 1980 |
Benade LE, Ihle JN. Different serotypes of B-tropic murine leukemia viruses and association with endogenous ecotropic viral loci. Virology. 106: 374-386. PMID 6254258 DOI: 10.1016/0042-6822(80)90260-3 |
0.308 |
|
| 1980 |
Horak I, Lee JC, Enjuanes L, Ihle JN. Characterization of a unique defective type C virus associated with a Moloney leukemia virus-induced splenic T-cell lymphoma cell line. Journal of Virology. 36: 299-308. PMID 6159481 DOI: 10.1128/Jvi.36.2.299-308.1980 |
0.368 |
|
| 1979 |
Lieberman M, Declève A, Ihle JN, Kaplan HS. Rescue of a thymotropic, leukemogenic C-type virus from cultured, nonproducer-lymphoma cells of strain C57BL/Ka mice. Virology. 97: 12-21. PMID 89753 DOI: 10.1016/0042-6822(79)90368-4 |
0.333 |
|
| 1978 |
Pazmiño NH, McEwan R, Ihle JN. Radiation leukemia in C57BL/6 mice. III. Correlation of altered expression of terminal deoxynucleotidyl transferase to induction of leukemia. Journal of Experimental Medicine. 148: 1338-1350. PMID 722241 DOI: 10.1084/Jem.148.5.1338 |
0.334 |
|
| 1978 |
Fischinger PJ, Frankel AE, Elder JH, Lerner RA, Ihle JN, Bolognesi DP. Biological, immunological, and biochemical evidence that HIX virus is a recombinant between moloney leukemia virus and a murine xenotropic C type virus Virology. 90: 241-254. PMID 214945 DOI: 10.1016/0042-6822(78)90308-2 |
0.324 |
|
| 1978 |
Ihle JN, Joseph DR. Serological and virological analysis of NIH (NIH X AKR) mice: evidence for three AKR murine leukemia virus loci. Virology. 87: 287-97. PMID 208276 DOI: 10.1016/0042-6822(78)90134-4 |
0.305 |
|
| 1978 |
Declève A, Lieberman M, Ihle JN, Rosenthal PN, Lung ML, Kaplan HS. Physicochemical, biological and serological properties of a leukemogenic virus isolated from cultured radl-V-induced lymphomas of C57BL/Ka mice Virology. 90: 23-35. PMID 82294 DOI: 10.1016/0042-6822(78)90329-X |
0.345 |
|
| 1976 |
Ihle JN, Collins JJ, Lee JC, Fischinger PJ, Moennig V, Schäfer W, Hanna MG, Bolognesi DP. Characterization of the immune response to the major glycoprotein (gp 71) of Friend leukemia virus. I. Response in BALB/c mice. Virology. 75: 74-87. PMID 982854 DOI: 10.1016/0042-6822(76)90008-8 |
0.326 |
|
| 1976 |
Ihle JN, Collins JJ, Lee JC, Fischinger PJ, Pazmino N, Moennig V, Schäfer W, Hanna MG, Bolognesi DP. Characterization of the immune response to the major glycoprotein (gp71) of friend leukemia virus III. Influence on endogenous MuLV-mediated pathogenesis Virology. 75: 102-112. PMID 982843 DOI: 10.1016/0042-6822(76)90010-6 |
0.321 |
|
| 1976 |
Decleve A, Lieberman M, Ihle JN, Kaplan HS. Biological and serological characterization of radiation leukemia virus. Proceedings of the National Academy of Sciences of the United States of America. 73: 4675-4679. PMID 188050 DOI: 10.1073/Pnas.73.12.4675 |
0.309 |
|
| 1976 |
Fischinger PJ, Ihle JN, Bolognesi DP, Schäfer W. Inactivation of murine xenotropic oncornavirus by normal mouse sera is not immunoglobulin-mediated Virology. 71: 346-351. PMID 179206 DOI: 10.1016/0042-6822(76)90118-5 |
0.328 |
|
| 1976 |
Ihle JN, Joseph DR, Pazmino NH. Radiation leukemia in C57BL/6 mice. II. Lack of ecotropic virus expression in the majority of lymphomas. The Journal of Experimental Medicine. 144: 1406-23. PMID 63529 DOI: 10.1084/Jem.144.6.1406 |
0.317 |
|
| 1974 |
Ihle JN, Kenney FT, Tennant RW. Evidence for a stable intermediate in leukemia virus activation in AKR mouse embryo cells. Journal of Virology. 14: 451-6. PMID 4604455 DOI: 10.1128/Jvi.14.3.451-456.1974 |
0.353 |
|
| Show low-probability matches. |