| Year |
Citation |
Score |
| 2023 |
Ciudad MT, Quevedo R, Lamorte S, Jin R, Nzirorera N, Koritzinsky M, McGaha TL. Dabrafenib alters MDSC differentiation and function by activation of GCN2. Biorxiv : the Preprint Server For Biology. PMID 37645997 DOI: 10.1101/2023.08.09.552588 |
0.331 |
|
| 2022 |
Lukhele S, Rabbo DA, Guo M, Shen J, Elsaesser HJ, Quevedo R, Carew M, Gadalla R, Snell LM, Mahesh L, Ciudad MT, Snow BE, You-Ten A, Haight J, Wakeham A, ... ... McGaha TL, et al. The transcription factor IRF2 drives interferon-mediated CD8 T cell exhaustion to restrict anti-tumor immunity. Immunity. PMID 36370712 DOI: 10.1016/j.immuni.2022.10.020 |
0.368 |
|
| 2022 |
Boukhaled GM, Gadalla R, Elsaesser HJ, Abd-Rabbo D, Quevedo R, Yang SYC, Guo M, Wang BX, Noamani B, Gray D, Lau SCM, Taylor K, Aung K, Spreafico A, Hansen AR, ... ... McGaha TL, et al. Pre-encoded responsiveness to type I interferon in the peripheral immune system defines outcome of PD1 blockade therapy. Nature Immunology. PMID 35835962 DOI: 10.1038/s41590-022-01262-7 |
0.317 |
|
| 2022 |
Makhijani P, McGaha TL. Myeloid Responses to Extracellular Vesicles in Health and Disease. Frontiers in Immunology. 13: 818538. PMID 35320943 DOI: 10.3389/fimmu.2022.818538 |
0.302 |
|
| 2022 |
Hezaveh K, Shinde RS, Klötgen A, Halaby MJ, Lamorte S, Ciudad MT, Quevedo R, Neufeld L, Liu ZQ, Jin R, Grünwald BT, Foerster EG, Chaharlangi D, Guo M, Makhijani P, ... ... McGaha TL, et al. Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity. Immunity. 55: 324-340.e8. PMID 35139353 DOI: 10.1016/j.immuni.2022.01.006 |
0.341 |
|
| 2021 |
Sharma MD, Pacholczyk R, Shi H, Berrong ZJ, Zakharia Y, Greco A, Chang CS, Eathiraj S, Kennedy E, Cash T, Bollag RJ, Kolhe R, Sadek R, McGaha TL, Rodriguez P, et al. Inhibition of the BTK-IDO-mTOR axis promotes differentiation of monocyte-lineage dendritic cells and enhances anti-tumor T cell immunity. Immunity. PMID 34614413 DOI: 10.1016/j.immuni.2021.09.005 |
0.332 |
|
| 2021 |
Lamorte S, Shinde R, McGaha TL. Nuclear receptors, the aryl hydrocarbon receptor, and macrophage function. Molecular Aspects of Medicine. 100942. PMID 33451803 DOI: 10.1016/j.mam.2021.100942 |
0.318 |
|
| 2020 |
Macleod BL, Elsaesser HJ, Snell LM, Dickson RJ, Guo M, Hezaveh K, Xu W, Kothari A, McGaha TL, Guidos CJ, Brooks DG. A network of immune and microbial modifications underlies viral persistence in the gastrointestinal tract. The Journal of Experimental Medicine. 217. PMID 32880629 DOI: 10.1084/Jem.20191473 |
0.401 |
|
| 2020 |
Romero JM, Grünwald BT, Jang GH, Bavi PP, Jhaveri A, Masoomian M, Fischer SE, Zhang A, Denroche RE, Lungu IM, De Luca A, Bartlett JMS, Xu J, Li N, Dhaliwal S, ... ... McGaha TL, et al. A four-chemokine signature is associated with a T cell-inflamed phenotype in primary and metastatic pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31964786 DOI: 10.1158/1078-0432.Ccr-19-2803 |
0.418 |
|
| 2019 |
Halaby MJ, Hezaveh K, Lamorte S, Ciudad MT, Kloetgen A, MacLeod BL, Guo M, Chakravarthy A, Medina TDS, Ugel S, Tsirigos A, Bronte V, Munn DH, Pugh TJ, De Carvalho DD, ... ... McGaha TL, et al. GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment. Science Immunology. 4. PMID 31836669 DOI: 10.1126/Sciimmunol.Aax8189 |
0.454 |
|
| 2019 |
Drohomyrecky PC, Doroshenko ER, Akkermann R, Moshkova M, Yi TJ, Zhao FL, Ahn JJ, McGaha TL, Pahan K, Dunn SE. Peroxisome Proliferator-Activated Receptor-δ Acts within Peripheral Myeloid Cells to Limit Th Cell Priming during Experimental Autoimmune Encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). PMID 31578267 DOI: 10.4049/Jimmunol.1801200 |
0.465 |
|
| 2019 |
Gadalla R, Noamani B, MacLeod BL, Dickson RJ, Guo M, Xu W, Lukhele S, Elsaesser HJ, Razak ARA, Hirano N, McGaha TL, Wang B, Butler M, Guidos CJ, Ohashi PS, et al. Validation of CyTOF Against Flow Cytometry for Immunological Studies and Monitoring of Human Cancer Clinical Trials. Frontiers in Oncology. 9: 415. PMID 31165047 DOI: 10.3389/Fonc.2019.00415 |
0.348 |
|
| 2019 |
Clouthier DL, Lien SC, Yang SYC, Nguyen LT, Manem VSK, Gray D, Ryczko M, Razak ARA, Lewin J, Lheureux S, Colombo I, Bedard PL, Cescon D, Spreafico A, Butler MO, ... ... McGaha T, et al. An interim report on the investigator-initiated phase 2 study of pembrolizumab immunological response evaluation (INSPIRE). Journal For Immunotherapy of Cancer. 7: 72. PMID 30867072 DOI: 10.1186/S40425-019-0541-0 |
0.331 |
|
| 2019 |
Bernal MO, Chepeha D, Prawira A, Vines D, Spreafico A, Bratman S, Almeida JD, Hansen A, Goldstein D, Gilbert R, Gullane P, Brown DH, Weinreb I, Perez-Ordoñez B, Ohashi PS, ... McGaha T, et al. Abstract CT124: Sitravatinib and nivolumab in oral cavity cancer window of opportunity study (SNOW) Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Ct124 |
0.326 |
|
| 2019 |
Romero JM, Grünwald B, Connor A, Jang GH, Bavi P, Jhaveri A, Masoomian M, Fischer S, Zhang A, Denroche RE, McGaha T, Notta F, Ohashi P, O'Kane G, Wilson J, et al. Abstract 1500: Mediators of CD8+cytotoxic T lymphocyte infiltration in pancreatic cancer Cancer Research. 79: 1500-1500. DOI: 10.1158/1538-7445.Am2019-1500 |
0.368 |
|
| 2018 |
Shinde R, McGaha TL. The Aryl Hydrocarbon Receptor: Connecting Immunity to the Microenvironment. Trends in Immunology. PMID 30409559 DOI: 10.1016/J.It.2018.10.010 |
0.383 |
|
| 2018 |
Snell LM, MacLeod BL, Law JC, Osokine I, Elsaesser HJ, Hezaveh K, Dickson RJ, Gavin MA, Guidos CJ, McGaha TL, Brooks DG. CD8 T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity. Immunity. PMID 30314757 DOI: 10.1016/J.Immuni.2018.08.002 |
0.382 |
|
| 2018 |
Shinde R, Hezaveh K, Halaby MJ, Kloetgen A, Chakravarthy A, da Silva Medina T, Deol R, Manion KP, Baglaenko Y, Eldh M, Lamorte S, Wallace D, Chodisetti SB, Ravishankar B, Liu H, ... ... McGaha TL, et al. Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans. Nature Immunology. PMID 29760532 DOI: 10.1038/S41590-018-0107-1 |
0.476 |
|
| 2017 |
Johnson TS, Mcgaha T, Munn DH. Chemo-immunotherapy: Role of indoleamine 2,3-dioxygenase in defining immunogenic versus tolerogenic cell death in the tumor microenvironment Advances in Experimental Medicine and Biology. 1036: 91-104. PMID 29275467 DOI: 10.1007/978-3-319-67577-0_7 |
0.438 |
|
| 2017 |
Snell LM, McGaha TL, Brooks DG. Type I Interferon in Chronic Virus Infection and Cancer. Trends in Immunology. PMID 28579323 DOI: 10.1016/J.It.2017.05.005 |
0.369 |
|
| 2016 |
Duhlin A, Chen Y, Wermeling F, Sedimbi SK, Lindh E, Shinde R, Halaby MJ, Kaiser Y, Winqvist O, McGaha TL, Karlsson MC. Selective Memory to Apoptotic Cell-Derived Self-Antigens with Implications for Systemic Lupus Erythematosus Development. Journal of Immunology (Baltimore, Md. : 1950). PMID 27559051 DOI: 10.4049/Jimmunol.1401129 |
0.334 |
|
| 2016 |
McGaha TL, Karlsson MC. Apoptotic cell responses in the splenic marginal zone: a paradigm for immunologic reactions to apoptotic antigens with implications for autoimmunity. Immunological Reviews. 269: 26-43. PMID 26683143 DOI: 10.1111/Imr.12382 |
0.468 |
|
| 2015 |
Sharma MD, Shinde R, McGaha TL, Huang L, Holmgaard RB, Wolchok JD, Mautino MR, Celis E, Sharpe AH, Francisco LM, Powell JD, Yagita H, Mellor AL, Blazar BR, Munn DH. The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment. Science Advances. 1: e1500845. PMID 26601142 DOI: 10.1126/Sciadv.1500845 |
0.386 |
|
| 2015 |
McGaha TL. IDO-GCN2 and autophagy in inflammation. Oncotarget. 6: 21771-2. PMID 26317232 DOI: 10.18632/Oncotarget.4846 |
0.493 |
|
| 2015 |
Ravishankar B, Liu H, Shinde R, Chaudhary K, Xiao W, Bradley J, Koritzinsky M, Madaio MP, McGaha TL. The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. PMID 26261340 DOI: 10.1073/Pnas.1504276112 |
0.486 |
|
| 2015 |
Shinde R, Shimoda M, Chaudhary K, Liu H, Mohamed E, Bradley J, Kandala S, Li X, Liu K, McGaha TL. B Cell-Intrinsic IDO1 Regulates Humoral Immunity to T Cell-Independent Antigens. Journal of Immunology (Baltimore, Md. : 1950). PMID 26216892 DOI: 10.4049/Jimmunol.1402854 |
0.458 |
|
| 2015 |
Chaudhary K, Shinde R, Liu H, Gnana-Prakasam JP, Veeranan-Karmegam R, Huang L, Ravishankar B, Bradley J, Kvirkvelia N, McMenamin M, Xiao W, Kleven D, Mellor AL, Madaio MP, McGaha TL. Amino Acid Metabolism Inhibits Antibody-Driven Kidney Injury by Inducing Autophagy. Journal of Immunology (Baltimore, Md. : 1950). 194: 5713-24. PMID 25980011 DOI: 10.4049/Jimmunol.1500277 |
0.354 |
|
| 2015 |
Paschall AV, Zhang R, Qi CF, Bardhan K, Peng L, Lu G, Yang J, Merad M, McGaha T, Zhou G, Mellor A, Abrams SI, Morse HC, Ozato K, Xiong H, et al. IFN regulatory factor 8 represses GM-CSF expression in T cells to affect myeloid cell lineage differentiation. Journal of Immunology (Baltimore, Md. : 1950). 194: 2369-79. PMID 25646302 DOI: 10.4049/Jimmunol.1402412 |
0.466 |
|
| 2015 |
Lemos H, Huang L, McGaha T, Mellor AL. STING, nanoparticles, autoimmune disease and cancer: a novel paradigm for immunotherapy? Expert Review of Clinical Immunology. 11: 155-65. PMID 25521938 DOI: 10.1586/1744666X.2015.995097 |
0.328 |
|
| 2015 |
Sharma M, Shinde R, McGaha T, Huang L, Holmgaard R, Wolchok J, Mautino M, Celis E, Sharpe A, Francisco L, Powell J, Yagita H, Mellor A, Blazar B, Munn D. The PTEN pathway in Tregs functions as a critical driver of the immunosuppressive tumor microenvironment and tolerance to apoptotic cells Journal For Immunotherapy of Cancer. 3: O19. DOI: 10.1186/2051-1426-3-S2-O19 |
0.444 |
|
| 2015 |
Paschall A, Zhang R, Bardhan K, Qi C, Peng L, Lu G, Yang J, Merad M, Zimmerman M, McGaha T, Zhou G, Mellor A, Abrams SI, Morse H, Ozato K, et al. Abstract PR05: IRF8 regulates GM-CSF expression in T cells and tumor cells to mediate myeloid-derived suppressor cell differentiation Cancer Immunology Research. 3. DOI: 10.1158/2326-6074.Tumimm14-Pr05 |
0.46 |
|
| 2014 |
McGaha TL, Madaio MP. Lupus Nephritis: Animal Modeling of a Complex Disease Syndrome Pathology. Drug Discovery Today. Disease Models. 11: 13-18. PMID 25722732 DOI: 10.1016/J.Ddmod.2014.08.002 |
0.309 |
|
| 2014 |
Lemos H, Huang L, McGaha TL, Mellor AL. Cytosolic DNA sensing via the stimulator of interferon genes adaptor: Yin and Yang of immune responses to DNA. European Journal of Immunology. 44: 2847-53. PMID 25143264 DOI: 10.1002/Eji.201344407 |
0.402 |
|
| 2014 |
Jha V, Workman CJ, McGaha TL, Li L, Vas J, Vignali DA, Monestier M. Lymphocyte Activation Gene-3 (LAG-3) negatively regulates environmentally-induced autoimmunity. Plos One. 9: e104484. PMID 25122007 DOI: 10.1371/Journal.Pone.0104484 |
0.454 |
|
| 2014 |
Ravishankar B, Shinde R, Liu H, Chaudhary K, Bradley J, Lemos HP, Chandler P, Tanaka M, Munn DH, Mellor AL, McGaha TL. Marginal zone CD169+ macrophages coordinate apoptotic cell-driven cellular recruitment and tolerance. Proceedings of the National Academy of Sciences of the United States of America. 111: 4215-20. PMID 24591636 DOI: 10.1073/Pnas.1320924111 |
0.494 |
|
| 2014 |
Liu H, Huang L, Bradley J, Liu K, Bardhan K, Ron D, Mellor AL, Munn DH, McGaha TL. GCN2-dependent metabolic stress is essential for endotoxemic cytokine induction and pathology. Molecular and Cellular Biology. 34: 428-38. PMID 24248597 DOI: 10.1128/Mcb.00946-13 |
0.371 |
|
| 2013 |
Huang L, Li L, Lemos H, Chandler PR, Pacholczyk G, Baban B, Barber GN, Hayakawa Y, McGaha TL, Ravishankar B, Munn DH, Mellor AL. Cutting edge: DNA sensing via the STING adaptor in myeloid dendritic cells induces potent tolerogenic responses. Journal of Immunology (Baltimore, Md. : 1950). 191: 3509-13. PMID 23986532 DOI: 10.4049/Jimmunol.1301419 |
0.439 |
|
| 2013 |
Ravishankar B, McGaha TL. O death where is thy sting? Immunologic tolerance to apoptotic self. Cellular and Molecular Life Sciences : Cmls. 70: 3571-89. PMID 23377225 DOI: 10.1007/S00018-013-1261-0 |
0.443 |
|
| 2012 |
McGaha TL, Huang L, Lemos H, Metz R, Mautino M, Prendergast GC, Mellor AL. Amino acid catabolism: a pivotal regulator of innate and adaptive immunity. Immunological Reviews. 249: 135-57. PMID 22889220 DOI: 10.1111/J.1600-065X.2012.01149.X |
0.372 |
|
| 2012 |
Huang L, Lemos HP, Li L, Li M, Chandler PR, Baban B, McGaha TL, Ravishankar B, Lee JR, Munn DH, Mellor AL. Engineering DNA nanoparticles as immunomodulatory reagents that activate regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 4913-20. PMID 22516958 DOI: 10.4049/Jimmunol.1103668 |
0.45 |
|
| 2012 |
Yang D, Torres CM, Bardhan K, Zimmerman M, McGaha TL, Liu K. Decitabine and vorinostat cooperate to sensitize colon carcinoma cells to Fas ligand-induced apoptosis in vitro and tumor suppression in vivo. Journal of Immunology (Baltimore, Md. : 1950). 188: 4441-9. PMID 22461695 DOI: 10.4049/Jimmunol.1103035 |
0.38 |
|
| 2012 |
Ravishankar B, Liu H, Shinde R, Chandler P, Baban B, Tanaka M, Munn DH, Mellor AL, Karlsson MC, McGaha TL. Tolerance to apoptotic cells is regulated by indoleamine 2,3-dioxygenase. Proceedings of the National Academy of Sciences of the United States of America. 109: 3909-14. PMID 22355111 DOI: 10.1073/Pnas.1117736109 |
0.511 |
|
| 2012 |
McGaha TL, Ma Z, Ravishankar B, Gabunia K, McMenamin M, Madaio MP. Heterologous protein incites abnormal plasma cell accumulation and autoimmunity in MRL-MpJ mice. Autoimmunity. 45: 279-89. PMID 22283427 DOI: 10.3109/08916934.2012.654864 |
0.423 |
|
| 2011 |
Enoksson SL, Grasset EK, Hägglöf T, Mattsson N, Kaiser Y, Gabrielsson S, McGaha TL, Scheynius A, Karlsson MC. The inflammatory cytokine IL-18 induces self-reactive innate antibody responses regulated by natural killer T cells. Proceedings of the National Academy of Sciences of the United States of America. 108: E1399-407. PMID 22135456 DOI: 10.1073/Pnas.1107830108 |
0.451 |
|
| 2011 |
McGaha TL, Chen Y, Ravishankar B, van Rooijen N, Karlsson MC. Marginal zone macrophages suppress innate and adaptive immunity to apoptotic cells in the spleen. Blood. 117: 5403-12. PMID 21444914 DOI: 10.1182/Blood-2010-11-320028 |
0.499 |
|
| 2010 |
Shao WH, Zhen Y, Rosenbaum J, Eisenberg RA, McGaha TL, Birkenbach M, Cohen PL. A protective role of Mer receptor tyrosine kinase in nephrotoxic serum-induced nephritis. Clinical Immunology (Orlando, Fla.). 136: 236-44. PMID 20444650 DOI: 10.1016/J.Clim.2010.04.002 |
0.395 |
|
| 2009 |
Wermeling F, Karlsson MC, McGaha TL. An anatomical view on macrophages in tolerance. Autoimmunity Reviews. 9: 49-52. PMID 19281880 DOI: 10.1016/J.Autrev.2009.03.004 |
0.402 |
|
| 2008 |
McGaha TL, Karlsson MC, Ravetch JV. FcgammaRIIB deficiency leads to autoimmunity and a defective response to apoptosis in Mrl-MpJ mice. Journal of Immunology (Baltimore, Md. : 1950). 180: 5670-9. PMID 18390752 DOI: 10.4049/Jimmunol.180.8.5670 |
0.482 |
|
| 2008 |
Belnoue E, Pihlgren M, McGaha TL, Tougne C, Rochat AF, Bossen C, Schneider P, Huard B, Lambert PH, Siegrist CA. APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells. Blood. 111: 2755-64. PMID 18180376 DOI: 10.1182/Blood-2007-09-110858 |
0.37 |
|
| 2006 |
Ehlers M, Fukuyama H, McGaha TL, Aderem A, Ravetch JV. TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE. The Journal of Experimental Medicine. 203: 553-61. PMID 16492804 DOI: 10.1084/Jem.20052438 |
0.379 |
|
| 2005 |
Bhogal RK, Stoica CM, McGaha TL, Bona CA. Molecular aspects of regulation of collagen gene expression in fibrosis. Journal of Clinical Immunology. 25: 592-603. PMID 16380822 DOI: 10.1007/S10875-005-7827-3 |
0.313 |
|
| 2005 |
McGaha TL, Sorrentino B, Ravetch JV. Restoration of tolerance in lupus by targeted inhibitory receptor expression. Science (New York, N.Y.). 307: 590-3. PMID 15681388 DOI: 10.1126/Science.1105160 |
0.379 |
|
| 2003 |
McGaha TL, Le M, Kodera T, Stoica C, Zhu J, Paul WE, Bona CA. Molecular mechanisms of interleukin-4-induced up-regulation of type I collagen gene expression in murine fibroblasts. Arthritis and Rheumatism. 48: 2275-84. PMID 12905482 DOI: 10.1002/Art.11089 |
0.326 |
|
| 2002 |
McGaha TL, Bona CA. Role of profibrogenic cytokines secreted by T cells in fibrotic processes in scleroderma. Autoimmunity Reviews. 1: 174-81. PMID 12849012 DOI: 10.1016/S1568-9972(02)00027-7 |
0.324 |
|
| 2002 |
McGaha T, Kodera T, Phelps R, Spiera H, Pines M, Bona C. Effect of halofuginone on the development of tight skin (TSK) syndrome. Autoimmunity. 35: 277-82. PMID 12482197 DOI: 10.1080/0891693021000001235 |
0.343 |
|
| 2002 |
Kodera T, McGaha TL, Phelps R, Paul WE, Bona CA. Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-beta production by fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 99: 3800-5. PMID 11891315 DOI: 10.1073/Pnas.052709999 |
0.326 |
|
| 2000 |
McGaha T, Murphy JW. CTLA-4 down-regulates the protective anticryptococcal cell-mediated immune response. Infection and Immunity. 68: 4624-30. PMID 10899865 DOI: 10.1128/Iai.68.8.4624-4630.2000 |
0.459 |
|
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