Year |
Citation |
Score |
2022 |
Wang W, Lu J, Yang WC, Spear ED, Michaelis S, Matunis MJ. Analysis of a degron-containing reporter protein GFP-CL1 reveals a role for SUMO1 in cytosolic protein quality control. The Journal of Biological Chemistry. 102851. PMID 36587767 DOI: 10.1016/j.jbc.2022.102851 |
0.616 |
|
2018 |
Spear ED, Hsu ET, Nie L, Carpenter EP, Hrycyna CA, Michaelis S. missense mutations that cause progeroid diseases decrease prelamin A cleavage activity and/or protein stability. Disease Models & Mechanisms. PMID 29794150 DOI: 10.1242/Dmm.033670 |
0.458 |
|
2016 |
Maurer MJ, Spear ED, Yu AT, Lee EJ, Shahzad S, Michaelis S. Degradation Signals for Ubiquitin-Proteasome Dependent Cytosolic Protein Quality Control (CytoQC) in Yeast. G3 (Bethesda, Md.). PMID 27172186 DOI: 10.1534/G3.116.027953 |
0.636 |
|
2014 |
Lee AY, St Onge RP, Proctor MJ, Wallace IM, Nile AH, Spagnuolo PA, Jitkova Y, Gronda M, Wu Y, Kim MK, Cheung-Ong K, Torres NP, Spear ED, Han MK, Schlecht U, et al. Mapping the cellular response to small molecules using chemogenomic fitness signatures. Science (New York, N.Y.). 344: 208-11. PMID 24723613 DOI: 10.1126/Science.1250217 |
0.303 |
|
2010 |
Kogan K, Spear ED, Kaiser CA, Fass D. Structural conservation of components in the amino acid sensing branch of the TOR pathway in yeast and mammals. Journal of Molecular Biology. 402: 388-98. PMID 20655927 DOI: 10.1016/J.Jmb.2010.07.034 |
0.544 |
|
2005 |
Kim W, Spear ED, Ng DT. Yos9p detects and targets misfolded glycoproteins for ER-associated degradation. Molecular Cell. 19: 753-64. PMID 16168371 DOI: 10.1016/J.Molcel.2005.08.010 |
0.74 |
|
2005 |
Spear ED, Ng DT. Single, context-specific glycans can target misfolded glycoproteins for ER-associated degradation. The Journal of Cell Biology. 169: 73-82. PMID 15809311 DOI: 10.1083/Jcb.200411136 |
0.715 |
|
2003 |
Spear ED, Ng DT. Stress tolerance of misfolded carboxypeptidase Y requires maintenance of protein trafficking and degradative pathways. Molecular Biology of the Cell. 14: 2756-67. PMID 12857862 DOI: 10.1091/Mbc.E02-11-0717 |
0.73 |
|
2001 |
Vashist S, Kim W, Belden WJ, Spear ED, Barlowe C, Ng DT. Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding The Journal of Cell Biology. 155: 355-368. PMID 11673477 DOI: 10.1083/Jcb.200106123 |
0.741 |
|
2001 |
Spear E, Ng DT. The unfolded protein response: no longer just a special teams player. Traffic (Copenhagen, Denmark). 2: 515-23. PMID 11489209 DOI: 10.1034/J.1600-0854.2001.20801.X |
0.713 |
|
2000 |
Ng DT, Spear ED, Walter P. The unfolded protein response regulates multiple aspects of secretory and membrane protein biogenesis and endoplasmic reticulum quality control. The Journal of Cell Biology. 150: 77-88. PMID 10893258 DOI: 10.1083/Jcb.150.1.77 |
0.72 |
|
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