Hiroaki Kiyokawa - Publications

Affiliations: 
University of Illinois at Chicago, Health Sciences Center, Chicago, IL 60612, United States 
Area:
Molecular Biology, Genetics, Cell Biology

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Year Citation  Score
2020 Owais A, Mishra RK, Kiyokawa H. The HECT E3 Ligase E6AP/UBE3A as a Therapeutic Target in Cancer and Neurological Disorders. Cancers. 12. PMID 32751183 DOI: 10.3390/Cancers12082108  0.317
2018 Roof AK, Jirawatnotai S, Trudeau T, Kuzyk C, Wierman ME, Kiyokawa H, Gutierrez-Hartmann A. The balance of PI3K and ERK signaling is dysregulated in prolactinoma and modulated by dopamine. Endocrinology. PMID 29726995 DOI: 10.1210/En.2017-03135  0.697
2018 Bhuripanyo K, Wang Y, Liu X, Zhou L, Liu R, Duong D, Zhao B, Bi Y, Zhou H, Chen G, Seyfried NT, Chazin WJ, Kiyokawa H, Yin J. Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer. Science Advances. 4: e1701393. PMID 29326975 DOI: 10.1126/Sciadv.1701393  0.363
2017 Gillam MP, Ku CR, Lee YJ, Kim J, Kim SH, Lee SJ, Hwang B, Koo J, Kineman RD, Kiyokawa H, Lee EJ. Somatotroph-Specific Aip-Deficient Mice Display Pretumorigenic Alterations in Cell-Cycle Signaling. Journal of the Endocrine Society. 1: 78-95. PMID 29264469 DOI: 10.1210/Js.2016-1004  0.455
2017 Wang Y, Liu X, Zhou L, Duong D, Bhuripanyo K, Zhao B, Zhou H, Liu R, Bi Y, Kiyokawa H, Yin J. Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer. Nature Communications. 8: 2232. PMID 29263404 DOI: 10.1038/S41467-017-01974-7  0.365
2017 Liu X, Sun L, Gursel DB, Cheng C, Huang S, Rademaker AW, Khan SA, Yin J, Kiyokawa H. The non-canonical ubiquitin activating enzyme UBA6 suppresses epithelial-mesenchymal transition of mammary epithelial cells. Oncotarget. 8: 87480-87493. PMID 29152096 DOI: 10.18632/Oncotarget.20900  0.465
2017 Liu X, Zhao B, Sun L, Bhuripanyo K, Wang Y, Bi Y, Davuluri RV, Duong DM, Nanavati D, Yin J, Kiyokawa H. Orthogonal ubiquitin transfer identifies ubiquitination substrates under differential control by the two ubiquitin activating enzymes. Nature Communications. 8: 14286. PMID 28134249 DOI: 10.1038/Ncomms14286  0.334
2015 Gillam MP, Nimbalkar D, Sun L, Christov K, Ray D, Kaldis P, Liu X, Kiyokawa H. MEN1 tumorigenesis in the pituitary and pancreatic islet requires CDK4 but not Cdk2 Oncogene. 34: 932-938. DOI: 10.1038/Onc.2014.3  0.469
2014 Bai F, Chan HL, Smith MD, Kiyokawa H, Pei XH. p19Ink4d is a tumor suppressor and controls pituitary anterior lobe cell proliferation. Molecular and Cellular Biology. 34: 2121-34. PMID 24687853 DOI: 10.1128/Mcb.01363-13  0.46
2014 Liu X, Gu X, Sun L, Flowers AB, Rademaker AW, Zhou Y, Kiyokawa H. Downregulation of Smurf2, a tumor-suppressive ubiquitin ligase, in triple-negative breast cancers: involvement of the RB-microRNA axis. Bmc Cancer. 14: 57. PMID 24485087 DOI: 10.1186/1471-2407-14-57  0.362
2012 Masyuk TV, Radtke BN, Stroope AJ, Banales JM, Masyuk AI, Gradilone SA, Gajdos GB, Chandok N, Bakeberg JL, Ward CJ, Ritman EL, Kiyokawa H, LaRusso NF. Inhibition of Cdc25A suppresses hepato-renal cystogenesis in rodent models of polycystic kidney and liver disease. Gastroenterology. 142: 622-633.e4. PMID 22155366 DOI: 10.1053/J.Gastro.2011.11.036  0.342
2011 Ray D, Ahsan A, Helman A, Chen G, Hegde A, Gurjar SR, Zhao L, Kiyokawa H, Beer DG, Lawrence TS, Nyati MK. Regulation of EGFR protein stability by the HECT-type ubiquitin ligase SMURF2. Neoplasia (New York, N.Y.). 13: 570-8. PMID 21750651 DOI: 10.1593/Neo.11632  0.354
2011 Ray D, Terao Y, Christov K, Kaldis P, Kiyokawa H. Cdk2-null mice are resistant to ErbB-2-induced mammary tumorigenesis. Neoplasia (New York, N.Y.). 13: 439-44. PMID 21532884 DOI: 10.1593/Neo.101704  0.524
2011 Beukelaers P, Vandenbosch R, Caron N, Nguyen L, Belachew S, Moonen G, Kiyokawa H, Barbacid M, Santamaria D, Malgrange B. Cdk6-dependent regulation of G(1) length controls adult neurogenesis. Stem Cells (Dayton, Ohio). 29: 713-24. PMID 21319271 DOI: 10.1002/Stem.616  0.349
2010 Taylor W, Mathias A, Ali A, Ke H, Stoynev N, Shilkaitis A, Green A, Kiyokawa H, Christov K. p27(Kip1) deficiency promotes prostate carcinogenesis but does not affect the efficacy of retinoids in suppressing the neoplastic process. Bmc Cancer. 10: 541. PMID 20932324 DOI: 10.1186/1471-2407-10-541  0.407
2010 Moore FE, Osmundson EC, Koblinski J, Pugacheva E, Golemis EA, Ray D, Kiyokawa H. The WW-HECT protein Smurf2 interacts with the Docking Protein NEDD9/HEF1 for Aurora A activation. Cell Division. 5: 22. PMID 20825672 DOI: 10.1186/1747-1028-5-22  0.698
2010 Adon AM, Zeng X, Harrison MK, Sannem S, Kiyokawa H, Kaldis P, Saavedra HI. Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells. Molecular and Cellular Biology. 30: 694-710. PMID 19933848 DOI: 10.1128/Mcb.00253-09  0.535
2009 Osmundson EC, Ray D, Moore FE, Kiyokawa H. Smurf2 as a novel mitotic regulator: From the spindle assembly checkpoint to tumorigenesis. Cell Division. 4: 14. PMID 19583833 DOI: 10.1186/1747-1028-4-14  0.709
2008 Aronovitz A, Josefson J, Fisher A, Newman M, Hughes E, Chen F, Moons DS, Kiyokawa H, Lowe WL. Rapamycin inhibits growth factor-induced cell cycle regulation in pancreatic beta cells. Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 56: 985-96. PMID 19105244 DOI: 10.2310/Jim.0B013E31818Ce763  0.467
2008 Kiyokawa H, Ray D. In vivo roles of CDC25 phosphatases: biological insight into the anti-cancer therapeutic targets. Anti-Cancer Agents in Medicinal Chemistry. 8: 832-6. PMID 19075565 DOI: 10.2174/187152008786847693  0.506
2008 Osmundson EC, Ray D, Moore FE, Gao Q, Thomsen GH, Kiyokawa H. The HECT E3 ligase Smurf2 is required for Mad2-dependent spindle assembly checkpoint. The Journal of Cell Biology. 183: 267-77. PMID 18852296 DOI: 10.1083/Jcb.200801049  0.71
2008 Gandin V, Miluzio A, Barbieri AM, Beugnet A, Kiyokawa H, Marchisio PC, Biffo S. Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation. Nature. 455: 684-8. PMID 18784653 DOI: 10.1038/Nature07267  0.433
2008 Shehu A, Mao J, Gibori GB, Halperin J, Le J, Devi YS, Merrill B, Kiyokawa H, Gibori G. Prolactin receptor-associated protein/17beta-hydroxysteroid dehydrogenase type 7 gene (Hsd17b7) plays a crucial role in embryonic development and fetal survival. Molecular Endocrinology (Baltimore, Md.). 22: 2268-77. PMID 18669642 DOI: 10.1210/Me.2008-0165  0.404
2008 Ray D, Kiyokawa H. CDC25A phosphatase: a rate-limiting oncogene that determines genomic stability. Cancer Research. 68: 1251-3. PMID 18316586 DOI: 10.1158/0008-5472.Can-07-5983  0.471
2008 Liu L, Schwartz B, Tsubota Y, Raines E, Kiyokawa H, Yonekawa K, Harlan JM, Schnapp LM. Cyclin-dependent kinase inhibitors block leukocyte adhesion and migration. Journal of Immunology (Baltimore, Md. : 1950). 180: 1808-17. PMID 18209078 DOI: 10.4049/Jimmunol.180.3.1808  0.396
2007 Ray D, Kiyokawa H. CDC25A levels determine the balance of proliferation and checkpoint response. Cell Cycle (Georgetown, Tex.). 6: 3039-42. PMID 18073536 DOI: 10.4161/Cc.6.24.5104  0.476
2007 Ray D, Terao Y, Nimbalkar D, Hirai H, Osmundson EC, Zou X, Franks R, Christov K, Kiyokawa H. Hemizygous disruption of Cdc25A inhibits cellular transformation and mammary tumorigenesis in mice. Cancer Research. 67: 6605-11. PMID 17638870 DOI: 10.1158/0008-5472.Can-06-4815  0.743
2007 Cooke PS, Holsberger DR, Cimafranca MA, Meling DD, Beals CM, Nakayama K, Nakayama KI, Kiyokawa H. The F box protein S phase kinase-associated protein 2 regulates adipose mass and adipocyte number in vivo. Obesity (Silver Spring, Md.). 15: 1400-8. PMID 17557977 DOI: 10.1038/Oby.2007.168  0.436
2007 Luque RM, Amargo G, Ishii S, Lobe C, Franks R, Kiyokawa H, Kineman RD. Reporter expression, induced by a growth hormone promoter-driven Cre recombinase (rGHp-Cre) transgene, questions the developmental relationship between somatotropes and lactotropes in the adult mouse pituitary gland. Endocrinology. 148: 1946-53. PMID 17289844 DOI: 10.1210/En.2006-1542  0.458
2007 Ray D, Terao Y, Fuhrken PG, Ma ZQ, DeMayo FJ, Christov K, Heerema NA, Franks R, Tsai SY, Papoutsakis ET, Kiyokawa H. Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability. Cancer Research. 67: 984-91. PMID 17283130 DOI: 10.1158/0008-5472.Can-06-3927  0.475
2006 Rachdi L, Balcazar N, Elghazi L, Barker DJ, Krits I, Kiyokawa H, Bernal-Mizrachi E. Differential effects of p27 in regulation of beta-cell mass during development, neonatal period, and adult life. Diabetes. 55: 3520-8. PMID 17130500 DOI: 10.2337/Db06-0861  0.412
2006 Skeen JE, Bhaskar PT, Chen CC, Chen WS, Peng XD, Nogueira V, Hahn-Windgassen A, Kiyokawa H, Hay N. Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner. Cancer Cell. 10: 269-80. PMID 17045205 DOI: 10.1016/J.Ccr.2006.08.022  0.505
2006 Kiyokawa H. Senescence and cell cycle control. Results and Problems in Cell Differentiation. 42: 257-70. PMID 16903214 DOI: 10.1007/400_001  0.419
2006 Ray D, Osmundson EC, Kiyokawa H. Constitutive and UV-induced fibronectin degradation is a ubiquitination-dependent process controlled by beta-TrCP. The Journal of Biological Chemistry. 281: 23060-5. PMID 16757476 DOI: 10.1074/Jbc.M604311200  0.668
2006 Sandoval R, Xue J, Tian X, Barrett K, Pilkinton M, Ucker DS, Raychaudhuri P, Kineman RD, Luque RM, Baida G, Zou X, Valli VE, Cook JL, Kiyokawa H, Colamonici OR. A mutant allele of BARA/LIN-9 rescues the cdk4-/- phenotype by releasing the repression on E2F-regulated genes. Experimental Cell Research. 312: 2465-75. PMID 16730350 DOI: 10.1016/J.Yexcr.2006.04.002  0.502
2006 Berthet C, Klarmann KD, Hilton MB, Suh HC, Keller JR, Kiyokawa H, Kaldis P. Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation. Developmental Cell. 10: 563-73. PMID 16678773 DOI: 10.1016/J.Devcel.2006.03.004  0.472
2006 Fatrai S, Elghazi L, Balcazar N, Cras-Méneur C, Krits I, Kiyokawa H, Bernal-Mizrachi E. Akt induces beta-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity. Diabetes. 55: 318-25. PMID 16443763 DOI: 10.2337/Diabetes.55.02.06.Db05-0757  0.476
2006 Yu Q, Sicinska E, Geng Y, Ahnström M, Zagozdzon A, Kong Y, Gardner H, Kiyokawa H, Harris LN, StÃ¥l O, Sicinski P. Requirement for CDK4 kinase function in breast cancer. Cancer Cell. 9: 23-32. PMID 16413469 DOI: 10.1016/J.Ccr.2005.12.012  0.359
2006 Kichina JV, Zeremski M, Aris L, Gurova KV, Walker E, Franks R, Nikitin AY, Kiyokawa H, Gudkov AV. Targeted disruption of the mouse ing1 locus results in reduced body size, hypersensitivity to radiation and elevated incidence of lymphomas Oncogene. 25: 857-866. PMID 16170338 DOI: 10.1038/Sj.Onc.1209118  0.439
2005 Abella A, Dubus P, Malumbres M, Rane SG, Kiyokawa H, Sicard A, Vignon F, Langin D, Barbacid M, Fajas L. Cdk4 promotes adipogenesis through PPARgamma activation. Cell Metabolism. 2: 239-49. PMID 16213226 DOI: 10.1016/J.Cmet.2005.09.003  0.515
2005 Mukai M, Dong Q, Hardy MP, Kiyokawa H, Peterson RE, Cooke PS. Altered prostatic epithelial proliferation and apoptosis, prostatic development, and serum testosterone in mice lacking cyclin-dependent kinase inhibitors. Biology of Reproduction. 73: 951-8. PMID 16014817 DOI: 10.1095/Biolreprod.105.040980  0.377
2005 Aleem E, Kiyokawa H, Kaldis P. Cdc2-cyclin E complexes regulate the G1/S phase transition. Nature Cell Biology. 7: 831-6. PMID 16007079 DOI: 10.1038/Ncb1284  0.503
2005 Ray D, Terao Y, Nimbalkar D, Chu LH, Donzelli M, Tsutsui T, Zou X, Ghosh AK, Varga J, Draetta GF, Kiyokawa H. Transforming growth factor beta facilitates beta-TrCP-mediated degradation of Cdc25A in a Smad3-dependent manner. Molecular and Cellular Biology. 25: 3338-47. PMID 15798217 DOI: 10.1128/Mcb.25.8.3338-3347.2005  0.342
2005 Holsberger DR, Buchold GM, Leal MC, Kiesewetter SE, O'Brien DA, Hess RA, França LR, Kiyokawa H, Cooke PS. Cell-cycle inhibitors p27Kip1 and p21Cip1 regulate murine Sertoli cell proliferation. Biology of Reproduction. 72: 1429-36. PMID 15728790 DOI: 10.1095/Biolreprod.105.040386  0.537
2005 Yoon T, Chakrabortty A, Franks R, Valli T, Kiyokawa H, Raychaudhuri P. Tumor-prone phenotype of the DDB2-deficient mice. Oncogene. 24: 469-78. PMID 15558025 DOI: 10.1038/Sj.Onc.1208211  0.44
2004 Krupczak-Hollis K, Wang X, Kalinichenko VV, Gusarova GA, Wang IC, Dennewitz MB, Yoder HM, Kiyokawa H, Kaestner KH, Costa RH. The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis. Developmental Biology. 276: 74-88. PMID 15531365 DOI: 10.1016/J.Ydbio.2004.08.022  0.376
2004 Naaz A, Holsberger DR, Iwamoto GA, Nelson A, Kiyokawa H, Cooke PS. Loss of cyclin-dependent kinase inhibitors produces adipocyte hyperplasia and obesity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1925-7. PMID 15469964 DOI: 10.1096/Fj.04-2631Fje  0.451
2004 Jirawatnotai S, Aziyu A, Osmundson EC, Moons DS, Zou X, Kineman RD, Kiyokawa H. Cdk4 is indispensable for postnatal proliferation of the anterior pituitary. The Journal of Biological Chemistry. 279: 51100-6. PMID 15456744 DOI: 10.1074/Jbc.M409080200  0.779
2004 Miliani de Marval PL, Macias E, Rounbehler R, Sicinski P, Kiyokawa H, Johnson DG, Conti CJ, Rodriguez-Puebla ML. Lack of cyclin-dependent kinase 4 inhibits c-myc tumorigenic activities in epithelial tissues. Molecular and Cellular Biology. 24: 7538-47. PMID 15314163 DOI: 10.1128/Mcb.24.17.7538-7547.2004  0.46
2004 Pei XH, Bai F, Tsutsui T, Kiyokawa H, Xiong Y. Genetic evidence for functional dependency of p18Ink4c on Cdk4. Molecular and Cellular Biology. 24: 6653-64. PMID 15254233 DOI: 10.1128/Mcb.24.15.6653-6664.2004  0.5
2004 Sandoval R, Xue J, Pilkinton M, Salvi D, Kiyokawa H, Colamonici OR. Different requirements for the cytostatic and apoptotic effects of type I interferons. Induction of apoptosis requires ARF but not p53 in osteosarcoma cell lines. The Journal of Biological Chemistry. 279: 32275-80. PMID 15169789 DOI: 10.1074/Jbc.M313830200  0.448
2004 Srivastava KK, Batra S, Sassano A, Li Y, Majchrzak B, Kiyokawa H, Altman A, Fish EN, Platanias LC. Engagement of protein kinase C-theta in interferon signaling in T-cells. The Journal of Biological Chemistry. 279: 29911-20. PMID 15150272 DOI: 10.1074/Jbc.M401997200  0.426
2003 Holsberger DR, Jirawatnotai S, Kiyokawa H, Cooke PS. Thyroid hormone regulates the cell cycle inhibitor p27Kip1 in postnatal murine Sertoli cells. Endocrinology. 144: 3732-8. PMID 12933641 DOI: 10.1210/En.2003-0389  0.752
2003 Jirawatnotai S, Moons DS, Stocco CO, Franks R, Hales DB, Gibori G, Kiyokawa H. The cyclin-dependent kinase inhibitors p27Kip1 and p21Cip1 cooperate to restrict proliferative life span in differentiating ovarian cells. The Journal of Biological Chemistry. 278: 17021-7. PMID 12609976 DOI: 10.1074/Jbc.M301206200  0.745
2002 Wang X, Kiyokawa H, Dennewitz MB, Costa RH. The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration. Proceedings of the National Academy of Sciences of the United States of America. 99: 16881-6. PMID 12482952 DOI: 10.1073/Pnas.252570299  0.458
2002 Zou X, Ray D, Aziyu A, Christov K, Boiko AD, Gudkov AV, Kiyokawa H. Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence. Genes & Development. 16: 2923-34. PMID 12435633 DOI: 10.1101/Gad.1033002  0.533
2002 Kwon YH, Jovanovic A, Serfas MS, Kiyokawa H, Tyner AL. P21 functions to maintain quiescence of p27-deficient hepatocytes. The Journal of Biological Chemistry. 277: 41417-22. PMID 12202477 DOI: 10.1074/Jbc.M203388200  0.424
2002 Rodriguez-Puebla ML, Miliani de Marval PL, LaCava M, Moons DS, Kiyokawa H, Conti CJ. Cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation. The American Journal of Pathology. 161: 405-11. PMID 12163365 DOI: 10.1016/S0002-9440(10)64196-X  0.424
2002 Moons DS, Jirawatnotai S, Parlow AF, Gibori G, Kineman RD, Kiyokawa H. Pituitary hypoplasia and lactotroph dysfunction in mice deficient for cyclin-dependent kinase-4. Endocrinology. 143: 3001-8. PMID 12130566 DOI: 10.1210/Endo.143.8.8956  0.735
2002 Moons DS, Jirawatnotai S, Tsutsui T, Franks R, Parlow AF, Hales DB, Gibori G, Fazleabas AT, Kiyokawa H. Intact follicular maturation and defective luteal function in mice deficient for cyclin- dependent kinase-4. Endocrinology. 143: 647-54. PMID 11796521 DOI: 10.1210/Endo.143.2.8611  0.766
2001 Miyazaki Y, Boccuni P, Mao S, Zhang J, Erdjument-Bromage H, Tempst P, Kiyokawa H, Nimer SD. Cyclin A-dependent phosphorylation of the ETS-related protein, MEF, restricts its activity to the G1 phase of the cell cycle. The Journal of Biological Chemistry. 276: 40528-36. PMID 11504716 DOI: 10.1074/JBC.M103051200  0.39
2001 Zou X, Tsutsui T, Ray D, Blomquist JF, Ichijo H, Ucker DS, Kiyokawa H. The cell cycle-regulatory CDC25a phosphatase inhibits apoptosis signal-regulating kinase 1 Molecular and Cellular Biology. 21: 4818-4828. PMID 11416155 DOI: 10.1128/Mcb.21.14.4818-4828.2001  0.482
2000 Teixeira LT, Kiyokawa H, Peng XD, Christov KT, Frohman LA, Kineman RD. p27Kip1-deficient mice exhibit accelerated growth hormone-releasing hormone (GHRH)-induced somatotrope proliferation and adenoma formation. Oncogene. 19: 1875-84. PMID 10773877 DOI: 10.1038/Sj.Onc.1203490  0.44
2000 Tsutsui T, Hesabi B, Moons DS, Pandolfi PP, Hansel KS, Koff A, Kiyokawa H. Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity. Molecular and Cellular Biology. 19: 7011-9. PMID 10490638 DOI: 10.1128/Mcb.19.10.7011  0.56
2000 Tyner AL, Kwon YH, Kiyokawa H, Serfas MS. Differential regulation of the CDK inhibitor p27 (KIP1) following CCL4 induced liver injury Gastroenterology. 118: A921. DOI: 10.1016/S0016-5085(00)85821-7  0.336
1999 Beumer TL, Kiyokawa H, Roepers-Gajadien HL, van den Bos LA, Lock TM, Gademan IS, Rutgers DH, Koff A, de Rooij DG. Regulatory role of p27kip1 in the mouse and human testis. Endocrinology. 140: 1834-40. PMID 10098522 DOI: 10.1210/Endo.140.4.6638  0.516
1998 Soos TJ, Park M, Kiyokawa H, Koff A. Regulation of the cell cycle by CDK inhibitors. Results and Problems in Cell Differentiation. 22: 111-31. PMID 9670321 DOI: 10.1007/978-3-540-69686-5_5  0.399
1997 Kiyokawa H, Koff A. Roles of cyclin-dependent kinase inhibitors: Lessons from knockout mice Current Topics in Microbiology and Immunology. 227: 105-120. PMID 9479827  0.343
1997 Langenfeld J, Kiyokawa H, Sekula D, Boyle J, Dmitrovsky E. Posttranslational regulation of cyclin D1 by retinoic acid: a chemoprevention mechanism. Proceedings of the National Academy of Sciences of the United States of America. 94: 12070-4. PMID 9342364 DOI: 10.1073/Pnas.94.22.12070  0.309
1997 Casaccia-Bonnefil P, Tikoo R, Kiyokawa H, Friedrich V, Chao MV, Koff A. Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27Kip1. Genes & Development. 11: 2335-46. PMID 9308962 DOI: 10.1101/Gad.11.18.2335  0.402
1997 Millard SS, Yan JS, Nguyen H, Pagano M, Kiyokawa H, Koff A. Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest. The Journal of Biological Chemistry. 272: 7093-8. PMID 9054402 DOI: 10.1074/Jbc.272.11.7093  0.367
1997 Luo Y, Marx SO, Kiyokawa H, Koff A, Massagué J, Marks AR. Rapamycin resistance tied to defective regulation of p27Kip1. Molecular and Cellular Biology. 16: 6744-51. PMID 8943329 DOI: 10.1128/Mcb.16.12.6744  0.377
1996 Missero C, Di Cunto F, Kiyokawa H, Koff A, Dotto GP. The absence of p21(Cip1/WAF1) alters keratinocyte growth and differentiation and promotes ras-tumor progression Genes and Development. 10: 3065-3075. PMID 8957006  0.347
1996 Kiyokawa H, Kineman RD, Manova-Todorova KO, Soares VC, Hoffman ES, Ono M, Khanam D, Hayday AC, Frohman LA, Koff A. Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). Cell. 85: 721-32. PMID 8646780 DOI: 10.1016/S0092-8674(00)81238-6  0.432
1994 Marks PA, Richon VM, Kiyokawa H, Rifkind RA. Inducing differentiation of transformed cells with hybrid polar compounds: a cell cycle-dependent process. Proceedings of the National Academy of Sciences of the United States of America. 91: 10251-4. PMID 7937935 DOI: 10.1073/pnas.91.22.10251  0.338
1994 Kiyokawa H, Richon VM, Rifkind RA, Marks PA. Suppression of cyclin-dependent kinase 4 during induced differentiation of erythroleukemia cells. Molecular and Cellular Biology. 14: 7195-203. PMID 7935434 DOI: 10.1128/MCB.14.11.7195  0.407
1993 Kiyokawa H, Richon VM, Venta-Perez G, Rifkind RA, Marks PA. Hexamethylenebisacetamide-induced erythroleukemia cell differentiation involves modulation of events required for cell cycle progression through G1. Proceedings of the National Academy of Sciences of the United States of America. 90: 6746-50. PMID 8341693 DOI: 10.1073/pnas.90.14.6746  0.337
Low-probability matches (unlikely to be authored by this person)
2013 Zhao B, Zhang K, Bhuripanyo K, Choi CH, Villhauer EB, Li H, Zheng N, Kiyokawa H, Schindelin H, Yin J. Profiling the cross reactivity of ubiquitin with the Nedd8 activating enzyme by phage display. Plos One. 8: e70312. PMID 23936405 DOI: 10.1371/Journal.Pone.0070312  0.299
2013 Zhao B, Zhang K, Villhauer EB, Bhuripanyo K, Kiyokawa H, Schindelin H, Yin J. Phage display to identify Nedd8-mimicking peptides as inhibitors of the Nedd8 transfer cascade. Chembiochem : a European Journal of Chemical Biology. 14: 1323-30. PMID 23824602 DOI: 10.1002/Cbic.201300234  0.287
2007 Shehu A, Mao J, Gibori G, Halperin J, Le J, Kiyokawa H, Gibori G. PRAP/17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 7 GENE PLAYS A CRUCIAL ROLE IN EMBRYONIC DEVELOPMENT AND FETAL SURVIVAL Biology of Reproduction. 77: 79-79. DOI: 10.1093/Biolreprod/77.S1.79A  0.282
2012 Zhao B, Bhuripanyo K, Zhang K, Kiyokawa H, Schindelin H, Yin J. Orthogonal ubiquitin transfer through engineered E1-E2 cascades for protein ubiquitination. Chemistry & Biology. 19: 1265-77. PMID 23102221 DOI: 10.1016/J.Chembiol.2012.07.023  0.282
2014 Zhao B, Villhauer EB, Bhuripanyo K, Kiyokawa H, Schindelin H, Yin J. SUMO-mimicking peptides inhibiting protein SUMOylation. Chembiochem : a European Journal of Chemical Biology. 15: 2662-6. PMID 25412743 DOI: 10.1002/Cbic.201402472  0.276
2020 Adon AM, Zeng X, Harrison MK, Sannem S, Kiyokawa H, Kaldis P, Saavedra HI. Correction for Adon et al., "Cdk2 and Cdk4 Regulate the Centrosome Cycle and Are Critical Mediators of Centrosome Amplification in p53-Null Cells". Molecular and Cellular Biology. 40. PMID 33159003 DOI: 10.1128/MCB.00488-20  0.275
1992 Kiyokawa H, Busquets X, Powell CT, Ngo L, Rifkind RA, Marks PA. Cloning of a D-type cyclin from murine erythroleukemia cells. Proceedings of the National Academy of Sciences of the United States of America. 89: 2444-7. PMID 1372445 DOI: 10.1073/pnas.89.6.2444  0.258
2021 Peng K, Liu R, Jia C, Wang Y, Jeong GH, Zhou L, Hu R, Kiyokawa H, Yin J, Zhao B. Regulation of O-Linked N-Acetyl Glucosamine Transferase (OGT) through E6 Stimulation of the Ubiquitin Ligase Activity of E6AP. International Journal of Molecular Sciences. 22. PMID 34638625 DOI: 10.3390/ijms221910286  0.258
1985 Hall IH, Williams WL, Chaney SG, Gilbert CJ, Holbrook DJ, Muraoka O, Kiyokawa H, Lee KH. Antitumor agents 68: effects of a series of helenalin derivatives on P-388 lymphocytic leukemia nucleic acid and protein synthesis. Journal of Pharmaceutical Sciences. 74: 250-4. PMID 2861271 DOI: 10.1002/Jps.2600740306  0.252
2014 Zhao B, Villhauer EB, Bhuripanyo K, Kiyokawa H, Schindelin H, Yin J. Back Cover: SUMO-Mimicking Peptides Inhibiting Protein SUMOylation (ChemBioChem 18/2014) Chembiochem. 15: 2792-2792. DOI: 10.1002/Cbic.201490066  0.248
1991 Richon VM, Weich N, Leng L, Kiyokawa H, Ngo L, Rifkind RA, Marks PA. Characteristics of erythroleukemia cells selected for vincristine resistance that have accelerated inducer-mediated differentiation. Proceedings of the National Academy of Sciences of the United States of America. 88: 1666-70. PMID 1672043 DOI: 10.1073/pnas.88.5.1666  0.248
2023 Peng K, Wang S, Liu R, Zhou L, Jeong GH, Jeong IH, Liu X, Kiyokawa H, Xue B, Zhao B, Shi H, Yin J. Effects of UBE3A on Cell and Liver Metabolism through the Ubiquitination of PDHA1 and ACAT1. Biochemistry. PMID 36920305 DOI: 10.1021/acs.biochem.2c00624  0.229
2021 Wang Y, Liu R, Liao J, Jiang L, Jeong GH, Zhou L, Polite M, Duong D, Seyfried NT, Wang H, Kiyokawa H, Yin J. Orthogonal ubiquitin transfer reveals human papillomavirus E6 downregulates nuclear transport to disarm interferon-γ dependent apoptosis of cervical cancer cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21986. PMID 34662469 DOI: 10.1096/fj.202101232RR  0.225
2023 Fang S, Chen G, Wang Y, Ganti R, Chernova TA, Zhou L, Jacobs SE, Duong D, Kiyokawa H, Chernoff YO, Li M, Shcherbik N, Zhao B, Yin J. Profiling and verifying the substrates of E3 ubiquitin ligase Rsp5 in yeast cells. Star Protocols. 4: 102489. PMID 37561636 DOI: 10.1016/j.xpro.2023.102489  0.215
2021 Wang Y, Fang S, Chen G, Ganti R, Chernova TA, Zhou L, Duong D, Kiyokawa H, Li M, Zhao B, Shcherbik N, Chernoff YO, Yin J. Regulation of the endocytosis and prion-chaperoning machineries by yeast E3 ubiquitin ligase Rsp5 as revealed by orthogonal ubiquitin transfer. Cell Chemical Biology. PMID 33667410 DOI: 10.1016/j.chembiol.2021.02.005  0.182
1992 Powell CT, Leng L, Dong L, Kiyokawa H, Busquets X, O'Driscoll K, Marks PA, Rifkind RA. Protein kinase C isozymes epsilon and alpha in murine erythroleukemia cells. Proceedings of the National Academy of Sciences of the United States of America. 89: 147-51. PMID 1729681 DOI: 10.1073/pnas.89.1.147  0.162
1982 Lee KH, Ibuka T, Sims D, Muraoka O, Kiyokawa H, Hall IH, Kim HL. Antitumor agents. 44. Bis(helenalinyl) esters and related derivatives as novel potent antileukemic agents. Journal of Medicinal Chemistry. 24: 924-7. PMID 7328595 DOI: 10.1002/Chin.198203148  0.155
2011 Terasaki Y, Yamamoto H, Kiyokawa H, Okumura H, Saito K, Ichinohasama R, Ishida Y. Disappearance of malignant cells by effusion drainage alone in two patients with HHV-8-unrelated HIV-negative primary effusion lymphoma-like lymphoma. International Journal of Hematology. 94: 279-84. PMID 21858447 DOI: 10.1007/s12185-011-0906-8  0.146
1985 Tani S, Fukamiya N, Kiyokawa H, Musallam HA, Pick RO, Lee KH. Antimalarial agents. 1. alpha-Santonin-derived cyclic peroxide as potential antimalarial agent. Journal of Medicinal Chemistry. 28: 1743-4. PMID 3906128 DOI: 10.1021/jm00149a034  0.105
1998 Kato H, Kiyokawa H, Igawa Y, Toguri AG, Nishizawa O. Frequent recurrence of superficial bladder tumors in the periorificial region: possible predictor for delayed appearance of invasive intramural ureteric cancer. International Journal of Urology : Official Journal of the Japanese Urological Association. 4: 623-4. PMID 9477198 DOI: 10.1111/j.1442-2042.1997.tb00323.x  0.082
1987 Yamamoto M, Takata S, Yagi S, Iwase N, Kiyokawa H, Noto Y, Ikeda T, Hattori N. Effects of insulin on pressor responsiveness and baroreflex function in diabetes mellitus. Japanese Circulation Journal. 50: 943-8. PMID 3543427 DOI: 10.1253/jcj.50.943  0.064
1993 Yoneyama T, Komatsu H, Kiyokawa H. Adenocarcinoma in an ileal conduit: recurrence of bladder adenocarcinoma. Urologia Internationalis. 50: 234-6. PMID 8389497 DOI: 10.1159/000282497  0.063
1988 Suzuki K, Kono N, Ono A, Osuga Y, Kiyokawa H, Mineo I, Matsuda Y, Miyoshi S, Kawata S, Minami Y. Transcatheter arterial chemo-embolization for humoral hypercalcemia of hepatocellular carcinoma. Gastroenterologia Japonica. 23: 29-36. PMID 2832239 DOI: 10.1007/BF02918853  0.053
2022 Kiyokawa H, Nagai T, Yamauchi Y, Kim J. The perception of translucency from surface gloss. Vision Research. 108140. PMID 36336645 DOI: 10.1016/j.visres.2022.108140  0.051
2000 Iizuka K, Igawa Y, Kato H, Kiyokawa H, Nishizawa O. Optimization of orthotopic colonic bladder: implantation of tubularized mucosal flap from colonic segment into demucosalized urethra. International Journal of Urology : Official Journal of the Japanese Urological Association. 7: 149-52. PMID 10810972 DOI: 10.1046/J.1442-2042.2000.00151.X  0.05
1988 Yagi S, Takata S, Kiyokawa H, Yamamoto M, Noto Y, Ikeda T, Hattori N. Effects of insulin on vasoconstrictive responses to norepinephrine and angiotensin II in rabbit femoral artery and vein. Diabetes. 37: 1064-7. PMID 3292327 DOI: 10.2337/diab.37.8.1064  0.044
2001 Kiyokawa H, Igawa Y, Nishizawa O. Hyperammonaemic encephalopathy associated with retention of urine in multiple large diverticula. Bju International. 88: 122-3. PMID 11446861 DOI: 10.1046/j.1464-410x.2001.02282.x  0.041
2021 Kiyokawa H, Tashiro T, Yamauchi Y, Nagai T. Spatial Frequency Effective for Increasing Perceived Glossiness by Contrast Enhancement. Frontiers in Psychology. 12: 625135. PMID 33613400 DOI: 10.3389/fpsyg.2021.625135  0.039
2001 Kato H, Kiyokawa H, Igawa Y, Nishizawa O. The serous-lined tunnel principle for urinary reconstruction: a more rational method. Bju International. 87: 783-8. PMID 11412214 DOI: 10.1046/j.1464-410x.2001.02229.x  0.032
2018 Aburadani I, Usuda K, Sumiya H, Sakagami S, Kiyokawa H, Matsuo S, Takamura M, Murai H, Takashima S, Kitano T, Okuda K, Nakajima K. Ability of the prognostic model of J-ACCESS study to predict cardiac events in a clinical setting: The APPROACH study. Journal of Cardiology. PMID 29317133 DOI: 10.1016/j.jjcc.2017.12.006  0.028
2019 Kiyokawa H, Tashiro T, Yamauchi Y, Nagai T. Luminance edge is a cue for glossiness perception based on low-luminance specular components. Journal of Vision. 19: 5. PMID 31613954 DOI: 10.1167/19.12.5  0.027
1999 Kiyokawa H, Igawa Y, Muraishi O, Tamai C, Nishizawa O. Simple anti-reflux uretero-ileal anastomosis: an experimental study in dogs. The Journal of Urology. 162: 902-4. PMID 10458405 DOI: 10.1097/00005392-199909010-00087  0.027
2023 Cai Y, Kiyokawa H, Nagai T, Haghzare L, Arnison M, Kim J. Effects of specular roughness on the perception of color and opacity. Journal of the Optical Society of America. a, Optics, Image Science, and Vision. 40: A220-A229. PMID 37133045 DOI: 10.1364/JOSAA.479972  0.021
2000 Kato H, Igawa Y, Kiyokawa H, Iwata K, Nishizawa O. Continent ileal pouch using the serous-lined principle. European Urology. 38: 100-3. PMID 10859450 DOI: 10.1159/000020260  0.019
1994 Yamaguchi K, Kiyokawa H, Machida J, Obayashi A, Nojiri N, Ueda S, Takatsuki K. Seroepidemiology of hepatitis C virus infection in Japan and HCV infection in haemodialysis patients. Fems Microbiology Reviews. 14: 253-8. PMID 7522023 DOI: 10.1111/j.1574-6976.1994.tb00096.x  0.015
2017 KIYOKAWA H, KAWASHIMA Y, YAMAUCHI Y, NAGAI T. Task-relevant Perceptual Learning for Judgments of Visual Material Features Transactions of Japan Society of Kansei Engineering. 17: 309-319. DOI: 10.5057/JJSKE.TJSKE-D-18-00019  0.01
1999 KIYOKAWA H, IGAWA Y, MURAISHI O, KATSUYAMA Y, IIZUKA K, NISHIZAWA O. DISTRIBUTION OF DOXORUBICIN IN THE BLADDER WALL AND REGIONAL LYMPH NODES AFTER BLADDER SUBMUCOSAL INJECTION OF LIPOSOMAL DOXORUBICIN IN THE DOG Journal of Urology. 161: 665-667. DOI: 10.1016/S0022-5347(01)61991-8  0.01
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