Elizabeth A. Eklund - Publications

Affiliations: 
Northwestern University, Evanston, IL 
Area:
Cell Biology, Molecular Biology, Oncology

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Year Citation  Score
2024 Khan I, Amin MA, Eklund EA, Gartel AL. Regulation of HOX gene expression in AML. Blood Cancer Journal. 14: 42. PMID 38453907 DOI: 10.1038/s41408-024-01004-y  0.449
2023 Chen H, Bai Y, Kobayashi M, Xiao S, Barajas S, Cai W, Chen S, Miao J, Nguele Meke F, Yao C, Yang Y, Strube K, Satchivi O, Sun J, Ronnstrand L, ... ... Eklund EA, et al. PRL2 phosphatase promotes oncogenic KIT signaling in leukemia cells through modulating CBL phosphorylation. Molecular Cancer Research : McR. PMID 37756563 DOI: 10.1158/1541-7786.MCR-23-0115  0.397
2023 Williams O, Hu L, Huang W, Patel P, Bartom ET, Bei L, Hjort E, Hijiya C, Eklund EA. Nore1 inhibits age-associated myeloid lineage skewing and clonal hematopoiesis but facilitates termination of emergency (stress) granulopoiesis. The Journal of Biological Chemistry. 299: 104867. PMID 37247756 DOI: 10.1016/j.jbc.2023.104867  0.385
2022 Chen H, Bai Y, Kobayashi M, Xiao S, Cai W, Barajas S, Chen S, Miao J, Nguele Meke F, Vemula S, Ropa J, Croop J, Boswell HS, Wan J, Jia Y, ... ... Eklund EA, et al. PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371. Blood. PMID 36206490 DOI: 10.1182/blood.2022016580  0.4
2021 Suarez M, Blyth GT, Mina AA, Kosciuczuk EM, Dolniak B, Dinner S, Altman JK, Eklund EA, Saleiro D, Beauchamp EM, Platanias LC. Inhibitory effects of Tomivosertib in acute myeloid leukemia. Oncotarget. 12: 955-966. PMID 34012509 DOI: 10.18632/oncotarget.27952  0.346
2020 Khan I, Eklund EA, Gartel AL. Therapeutic vulnerabilities of transcription factors in AML. Molecular Cancer Therapeutics. PMID 33158995 DOI: 10.1158/1535-7163.MCT-20-0115  0.424
2020 Wang H, Shah CA, Hu L, Huang W, Platanias LC, Eklund EA. An aberrantly sustained emergency granulopoiesis response accelerates post chemotherapy relapse in MLL1-rearranged acute myeloid leukemia in mice. The Journal of Biological Chemistry. PMID 32467231 DOI: 10.1074/Jbc.Ra120.013206  0.521
2020 Huang W, Liu B, Eklund EA. Investigating the role of the innate immune response in relapse or blast crisis in chronic myeloid leukemia. Leukemia. PMID 32080344 DOI: 10.1038/S41375-020-0771-7  0.474
2019 Kosciuczuk EM, Kar AK, Blyth GT, Fischietti M, Abedin S, Mina AA, Siliezar R, Rzymski T, Brzozka K, Eklund EA, Beauchamp EM, Eckerdt F, Saleiro D, Platanias LC. Inhibitory effects of SEL201 in acute myeloid leukemia. Oncotarget. 10: 7112-7121. PMID 31903169 DOI: 10.18632/Oncotarget.27388  0.513
2018 Beauchamp EM, Abedin SM, Radecki SG, Fischietti M, Arslan AD, Blyth GT, Yang A, Lantz C, Nelson A, Goo YA, Akpan I, Eklund EA, Frankfurt O, Fish EN, Thomas PM, et al. Identification and targeting of novel CDK9 complexes in acute myeloid leukemia. Blood. PMID 30587525 DOI: 10.1182/Blood-2018-08-870089  0.493
2018 Suraneni PK, Corey SJ, Hession MJ, Ishaq R, Awomolo A, Hasan S, Shah C, Liu H, Wickrema A, Debili N, Crispino JD, Eklund EA, Chen Y. Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activity. Blood Advances. 2: 3540-3552. PMID 30538113 DOI: 10.1182/Bloodadvances.2018021923  0.42
2018 Huang W, Bei L, Eklund EA. Inhibition of Fas associated phosphatase 1 (Fap1) facilitates apoptosis of colon cancer stem cells and enhances the effects of oxaliplatin. Oncotarget. 9: 25891-25902. PMID 29899829 DOI: 10.18632/Oncotarget.25401  0.436
2018 Wang H, Bei L, Shah CA, Huang W, Platanias LC, Eklund EA. The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia. Oncogene. PMID 29459712 DOI: 10.1038/S41388-018-0131-5  0.548
2018 Hu L, Huang W, Bei L, Broglie L, Eklund EA. TP53 Haploinsufficiency Rescues Emergency Granulopoiesis in FANCC-/- Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 29427417 DOI: 10.4049/Jimmunol.1700931  0.413
2018 Shah CA, Broglie L, Hu L, Bei L, Huang W, Dressler DB, Eklund EA. Stat3 and CCAAT enhancer-binding protein β (C/ebpβ) activate Fanconi C gene transcription during emergency granulopoiesis. The Journal of Biological Chemistry. PMID 29382715 DOI: 10.1074/Jbc.Ra117.000528  0.458
2018 Chae H, Murphy LC, Donato M, Lee AG, Sweet-Cordero EA, Abidi P, Bittencourt H, Lacayo NJ, Dahl GVH, Aftandilian C, Davis KL, Huang M, Sumarsono N, Redell M, Fu CH, ... ... Eklund EA, et al. Comparison of the Transcriptomic Signature of Pediatric Vs. Adult CML and Normal Bone Marrow Stem Cells Blood. 132: 4246-4246. DOI: 10.1182/Blood-2018-99-119974  0.454
2018 Suraneni PK, Corey SJ, Hession M, Ishaq R, Awomolo A, Hasan S, Debili N, Crispino JD, Eklund EA, Chen Y. Dynamins 2 and 3 Are Required for Human Megakaryocytes Directional Migration Blood. 132: 2429-2429. DOI: 10.1182/Blood-2018-99-118782  0.434
2017 Huang W, Bei L, Hjort EE, Eklund EA. Decreased calpain activity in chronic myeloid leukemia impairs apoptosis by increasing survivin in myeloid progenitors and xiap1 in differentiating granulocytes. Oncotarget. 8: 50629-50641. PMID 28881589 DOI: 10.18632/Oncotarget.16884  0.495
2017 Huang W, Bei L, Hjort EE, Eklund EA. Decreased Calpain activity in chronic myeloid leukemia impairs apoptosis by increasing Survivin in myeloid progenitors and xiap1 in differentiating granulocytes. Oncotarget. PMID 28431398 DOI: 10.18632/oncotarget.16884  0.399
2017 Kroczynska B, Blyth GT, Rafidi RL, Majchrzak-Kita B, Xu L, Saleiro D, Kosciuczuk EM, Jemielity J, Su B, Altman JK, Eklund EA, Fish EH, Platanias LC. Central Regulatory Role for SIN1 in Interferon γ (IFNγ) Signaling and Generation of Biological Responses. The Journal of Biological Chemistry. PMID 28174303 DOI: 10.1074/Jbc.M116.757666  0.498
2016 Hjort EE, Huang W, Hu L, Eklund EA. Bcr-abl regulates Stat5 through Shp2, the interferon consensus sequence binding protein (Icsbp/Irf8), growth arrest specific 2 (Gas2) and calpain. Oncotarget. PMID 27769062 DOI: 10.18632/Oncotarget.12749  0.609
2016 Shah CA, Bei L, Wang H, Altman JK, Platanias LC, Eklund EA. Cooperation between AlphavBeta3 integrin and the fibroblast growth factor receptor enhances proliferation of Hox-overexpressing acute myeloid leukemia cells. Oncotarget. PMID 27340869 DOI: 10.18632/Oncotarget.10189  0.591
2016 Huang W, Luan CH, Hjort EE, Bei L, Mishra R, Sakamoto KM, Platanias LC, Eklund EA. The role of Fas-associated phosphatase 1 in leukemia stem cell-persistence during tyrosine kinase inhibitor-treatment of chronic myeloid leukemia. Leukemia. PMID 26984787 DOI: 10.1038/Leu.2016.66  0.453
2016 Konieczna IM, DeLuca TA, Eklund EA, Miller WM. Hoxa10 null animals exhibit reduced platelet biogenesis. British Journal of Haematology. 173: 303-13. PMID 26847476 DOI: 10.1111/Bjh.13949  0.714
2016 Mitton B, Hsu K, Dutta R, Tiu BC, Cox N, McLure KG, Chae HD, Smith M, Eklund EA, Solow-Cordero DE, Sakamoto KM. Small molecule screen for inhibitors of expression from canonical CREB response element-containing promoters. Oncotarget. PMID 26840025 DOI: 10.18632/Oncotarget.7085  0.394
2016 Konieczna IM, Deluca TA, Eklund EA, Miller WM. Hoxa10 null animals exhibit reduced platelet biogenesis British Journal of Haematology. DOI: 10.1111/bjh.13949  0.638
2015 Hu L, Huang W, Hjort EE, Bei L, Platanias LC, Eklund EA. The Interferon Consensus Sequence Binding Protein (Icsbp/Irf8) is Required for Termination of Emergency Granulopoiesis. The Journal of Biological Chemistry. PMID 26683374 DOI: 10.1074/Jbc.M115.681361  0.553
2015 Wang H, Bei L, Shah CA, Hu L, Eklund EA. HoxA10 Terminates Emergency Granulopoiesis by Increasing Expression of Triad1. Journal of Immunology (Baltimore, Md. : 1950). 194: 5375-87. PMID 25895533 DOI: 10.4049/Jimmunol.1401909  0.557
2015 Sakamoto KM, Grant S, Saleiro D, Crispino JD, Hijiya N, Giles F, Platanias L, Eklund EA. Targeting novel signaling pathways for resistant acute myeloid leukemia. Molecular Genetics and Metabolism. 114: 397-402. PMID 25533111 DOI: 10.1016/J.Ymgme.2014.11.017  0.392
2014 Kroczynska B, Mehrotra S, Majchrzak-Kita B, Arslan AD, Altman JK, Stein BL, McMahon B, Kozlowski P, Kahle PJ, Eklund EA, Fish EN, Platanias LC. Regulatory effects of SKAR in interferon α signaling and its role in the generation of type I IFN responses. Proceedings of the National Academy of Sciences of the United States of America. 111: 11377-82. PMID 25049393 DOI: 10.1073/Pnas.1405250111  0.44
2014 Altman JK, Szilard A, Goussetis DJ, Sassano A, Colamonici M, Gounaris E, Frankfurt O, Giles FJ, Eklund EA, Beauchamp EM, Platanias LC. Autophagy is a survival mechanism of acute myelogenous leukemia precursors during dual mTORC2/mTORC1 targeting. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 2400-9. PMID 24610825 DOI: 10.1158/1078-0432.Ccr-13-3218  0.4
2014 Wu EJ, Goussetis DJ, Beauchamp E, Kosciuczuk EM, Altman JK, Eklund EA, Platanias LC. Resveratrol enhances the suppressive effects of arsenic trioxide on primitive leukemic progenitors. Cancer Biology & Therapy. 15: 473-8. PMID 24496081 DOI: 10.4161/Cbt.27824  0.429
2014 Bei L, Shah C, Wang H, Eklund E. Constitutive Activation of Shp2 Cooperates with MLL1 Fusion Proteins to Increase Expression of the Homeodomain Transcription Factors Cdx4, HoxA9 and HoxA10 Blood. 124: 3537-3537. DOI: 10.1182/Blood.V124.21.3537.3537  0.614
2014 Bei L, Shah C, Wang H, Huang W, Platanias LC, Eklund EA. Regulation of CDX4 gene transcription by HoxA9, HoxA10, the Mll-Ell oncogene and Shp2 during leukemogenesis Oncogenesis. 3. DOI: 10.1038/oncsis.2014.49  0.555
2013 Shah CA, Bei L, Wang H, Platanias LC, Eklund EA. The leukemia-associated Mll-Ell oncoprotein induces fibroblast growth factor 2 (Fgf2)-dependent cytokine hypersensitivity in myeloid progenitor cells. The Journal of Biological Chemistry. 288: 32490-505. PMID 24089521 DOI: 10.1074/Jbc.M113.496109  0.537
2013 Hu L, Huang W, Hjort E, Eklund EA. Increased Fanconi C expression contributes to the emergency granulopoiesis response. The Journal of Clinical Investigation. 123: 3952-66. PMID 23925293 DOI: 10.1172/Jci69032  0.495
2013 Mehrotra S, Sharma B, Joshi S, Kroczynska B, Majchrzak B, Stein BL, McMahon B, Altman JK, Licht JD, Baker DP, Eklund EA, Wickrema A, Verma A, Fish EN, Platanias LC. Essential role for the Mnk pathway in the inhibitory effects of type I interferons on myeloproliferative neoplasm (MPN) precursors. The Journal of Biological Chemistry. 288: 23814-22. PMID 23814052 DOI: 10.1074/Jbc.M113.476192  0.44
2013 Huang W, Bei L, Eklund EA. Fas-associated phosphatase 1 (Fap1) influences βcatenin activity in myeloid progenitor cells expressing the Bcr-abl oncogene. The Journal of Biological Chemistry. 288: 12766-76. PMID 23519466 DOI: 10.1074/Jbc.M112.429696  0.519
2013 Konieczna IM, Panuganti S, DeLuca TA, Papoutsakis ET, Eklund EA, Miller WM. Administration of nicotinamide does not increase platelet levels in mice. Blood Cells, Molecules & Diseases. 50: 171-6. PMID 23265740 DOI: 10.1016/J.Bcmd.2012.11.007  0.69
2013 Huang W, Bei L, Eklund EA. Fas-associated phosphatase 1 mediates Fas resistance in myeloid progenitor cells expressing the Bcr-abl oncogene. Leukemia & Lymphoma. 54: 619-30. PMID 22891763 DOI: 10.3109/10428194.2012.720979  0.52
2013 Shah C, Wang H, Bei L, Eklund E. Increased Expression Of Fgf2 Induces Cytokine Hypersensitivity In Leukemia Stem Cells With Translocations Involving The MLL Gene Blood. 122: 3791-3791. DOI: 10.1182/Blood.V122.21.3791.3791  0.585
2012 Bei L, Shah C, Wang H, Huang W, Roy R, Eklund EA. β-Catenin activates the HOXA10 and CDX4 genes in myeloid progenitor cells. The Journal of Biological Chemistry. 287: 39589-601. PMID 23038246 DOI: 10.1074/Jbc.M112.402172  0.476
2012 Kroczynska B, Sharma B, Eklund EA, Fish EN, Platanias LC. Regulatory effects of programmed cell death 4 (PDCD4) protein in interferon (IFN)-stimulated gene expression and generation of type I IFN responses. Molecular and Cellular Biology. 32: 2809-22. PMID 22586265 DOI: 10.1128/Mcb.00310-12  0.448
2012 Shah CA, Bei L, Wang H, Platanias LC, Eklund EA. HoxA10 protein regulates transcription of gene encoding fibroblast growth factor 2 (FGF2) in myeloid cells. The Journal of Biological Chemistry. 287: 18230-48. PMID 22493287 DOI: 10.1074/Jbc.M111.328401  0.563
2012 Huang W, Hu L, Bei L, Hjort E, Eklund EA. The leukemia-associated fusion protein Tel-platelet-derived growth factor receptor β (Tel-PdgfRβ) inhibits transcriptional repression of PTPN13 gene by interferon consensus sequence binding protein (Icsbp). The Journal of Biological Chemistry. 287: 8110-25. PMID 22262849 DOI: 10.1074/Jbc.M111.294884  0.586
2012 Eklund E. The role of Hox proteins in leukemogenesis: insights into key regulatory events in hematopoiesis. Critical Reviews in Oncogenesis. 16: 65-76. PMID 22150308 DOI: 10.1615/Critrevoncog.V16.I1-2.70  0.518
2012 Eklund EA. Regulation of Myelopoiesis by Differentiation Stage-Specific Activities of HOXA9 and HOXA10 Blood. 120: SCI-29-SCI-29. DOI: 10.1182/Blood.V120.21.Sci-29.Sci-29  0.585
2012 Hjort E, Huang W, Eklund EA. Bcr-Abl Represses IRF8 Gene Transcription in a Stat5-Dependent Manner Blood. 120: 3497-3497. DOI: 10.1182/Blood.V120.21.3497.3497  0.634
2012 Huang W, Bei L, Eklund EA. Fap1 Controls Beta-Catenin Activity in a Gsk3-Beta Dependent Manner in Chronic Myeloid Leukemia. Blood. 120: 2404-2404. DOI: 10.1182/Blood.V120.21.2404.2404  0.355
2011 Eklund EA, Platanias LC. Inhibition of histone deacetylase 6 as a therapeutic strategy for acute lymphocytic leukemia. Leukemia & Lymphoma. 52: 1421-2. PMID 21657957 DOI: 10.3109/10428194.2011.577259  0.336
2011 Bei L, Huang W, Wang H, Shah C, Horvath E, Eklund E. HoxA10 activates CDX4 transcription and Cdx4 activates HOXA10 transcription in myeloid cells. The Journal of Biological Chemistry. 286: 19047-64. PMID 21471217 DOI: 10.1074/Jbc.M110.213983  0.604
2011 Wang H, Bei L, Shah CA, Horvath E, Eklund EA. HoxA10 influences protein ubiquitination by activating transcription of ARIH2, the gene encoding Triad1. The Journal of Biological Chemistry. 286: 16832-45. PMID 21454682 DOI: 10.1074/Jbc.M110.213975  0.623
2011 Shah CA, Wang H, Bei L, Platanias LC, Eklund EA. HoxA10 regulates transcription of the gene encoding transforming growth factor beta2 (TGFbeta2) in myeloid cells. The Journal of Biological Chemistry. 286: 3161-76. PMID 21087928 DOI: 10.1074/Jbc.M110.183251  0.593
2011 Kroczynska B, Joshi S, Eklund EA, Verma A, Kotenko SV, Fish EN, Platanias LC. Regulatory effects of ribosomal S6 kinase 1 (RSK1) in IFNλ signaling. The Journal of Biological Chemistry. 286: 1147-56. PMID 21075852 DOI: 10.1074/Jbc.M110.183566  0.486
2011 Huang W, Eklund EA. Icsbp/Irf8 Cooperates with Tel to Regulate Fas Induced Apoptosis in Myeloid Leukemia. Blood. 118: 395-395. DOI: 10.1182/Blood.V118.21.395.395  0.565
2010 Shinnick KM, Eklund EA, McGarry TJ. Geminin deletion from hematopoietic cells causes anemia and thrombocytosis in mice Journal of Clinical Investigation. 120: 4303-4315. PMID 21041951 DOI: 10.1172/Jci43556  0.451
2010 Huang W, Zhou W, Saberwal G, Konieczna I, Horvath E, Katsoulidis E, Platanias LC, Eklund EA. Interferon consensus sequence binding protein (ICSBP) decreases beta-catenin activity in myeloid cells by repressing GAS2 transcription. Molecular and Cellular Biology. 30: 4575-94. PMID 20679491 DOI: 10.1128/Mcb.01595-09  0.753
2010 Eklund EA. Genomic analysis of acute myeloid leukemia: potential for new prognostic indicators. Current Opinion in Hematology. 17: 75-8. PMID 20075726 DOI: 10.1097/Moh.0B013E3283366C43  0.336
2010 Shah C, Wang H, Eklund EA. HoxA10 Regulates Myeloid Progenitor Proliferation by Activating Transcription of the Gene Encoding Transforming Growth Factor Beta 2. Blood. 116: 1572-1572. DOI: 10.1182/Blood.V116.21.1572.1572  0.641
2010 Huang W, Eklund E. SS5-4 Constitutive activation of Shp2 blocks IFNγ-stimulated increase in Fas-sensitivity in monocytes and granulocytes Cytokine. 52: 44-45. DOI: 10.1016/J.Cyto.2010.07.187  0.324
2009 Saberwal G, Horvath E, Hu L, Zhu C, Hjort E, Eklund EA. The interferon consensus sequence binding protein (ICSBP/IRF8) activates transcription of the FANCF gene during myeloid differentiation. The Journal of Biological Chemistry. 284: 33242-54. PMID 19801548 DOI: 10.1074/Jbc.M109.010231  0.601
2009 Katsoulidis E, Carayol N, Woodard J, Konieczna I, Majchrzak-Kita B, Jordan A, Sassano A, Eklund EA, Fish EN, Platanias LC. Role of Schlafen 2 (SLFN2) in the generation of interferon alpha-induced growth inhibitory responses. The Journal of Biological Chemistry. 284: 25051-64. PMID 19592487 DOI: 10.1074/Jbc.M109.030445  0.742
2009 Wang H, Lindsey S, Konieczna I, Bei L, Horvath E, Huang W, Saberwal G, Eklund EA. Constitutively active SHP2 cooperates with HoxA10 overexpression to induce acute myeloid leukemia. The Journal of Biological Chemistry. 284: 2549-67. PMID 19022774 DOI: 10.1074/Jbc.M804704200  0.832
2009 Huang W, Horvath E, Eklund EA. Bcr/Abl Increases Bcatenin Protein and Activity in An ICSBP-Dependent Manner in Myeloid Cells. Blood. 114: 2958-2958. DOI: 10.1182/Blood.V114.22.2958.2958  0.583
2009 Shinnick KM, Barry KA, Eklund EA, McGarry TJ. Geminin Regulates Hematopoietic Stem Cell Proliferation and Differentiation. Blood. 114: 1478-1478. DOI: 10.1182/Blood.V114.22.1478.1478  0.479
2008 Kaur S, Sassano A, Joseph AM, Majchrzak-Kita B, Eklund EA, Verma A, Brachmann SM, Fish EN, Platanias LC. Dual regulatory roles of phosphatidylinositol 3-kinase in IFN signaling. Journal of Immunology (Baltimore, Md. : 1950). 181: 7316-23. PMID 18981154 DOI: 10.4049/Jimmunol.181.10.7316  0.438
2008 Konieczna I, Horvath E, Wang H, Lindsey S, Saberwal G, Bei L, Huang W, Platanias L, Eklund EA. Constitutive activation of SHP2 in mice cooperates with ICSBP deficiency to accelerate progression to acute myeloid leukemia. The Journal of Clinical Investigation. 118: 853-67. PMID 18246201 DOI: 10.1172/Jci33742  0.805
2008 Huang W, Zhu C, Wang H, Horvath E, Eklund EA. The interferon consensus sequence-binding protein (ICSBP/IRF8) represses PTPN13 gene transcription in differentiating myeloid cells. The Journal of Biological Chemistry. 283: 7921-35. PMID 18195016 DOI: 10.1074/Jbc.M706710200  0.601
2008 Zhu C, Lindsey S, Konieczna I, Eklund EA. Constitutive activation of SHP2 protein tyrosine phosphatase inhibits ICSBP-induced transcription of the gene encoding gp91PHOX during myeloid differentiation. Journal of Leukocyte Biology. 83: 680-91. PMID 18089853 DOI: 10.1189/Jlb.0807514  0.803
2008 Eklund EA. The Role of Hox Proteins and Interferon Regulatory Factors in Myeloid Differentiation. Blood. 112: sci-34-sci-34. DOI: 10.1182/Blood.V112.11.Sci-34.Sci-34  0.594
2008 Wang H, Lindsey S, Konieczna I, Horvath E, Bei L, Huang W, Eklund EA. Constitutive Activation of SHP2 Protein Tyrosine Phosphatase Cooperates with HoxA10 Overexpression for Progression to Acute Myeloid Leukemia in a Murine Model Blood. 112: 752-752. DOI: 10.1182/Blood.V112.11.752.752  0.819
2008 Kaur S, Sassano A, Joseph AM, Majchrzak-Kita B, Eklund EA, Fish EN, Verma A, Brachmann SM, Platanias LC. 1 Dual regulatory roles of the phosphatidylinositol 3-kinase in interferon signaling Cytokine. 43: 237. DOI: 10.1016/J.Cyto.2008.07.041  0.319
2007 Bei L, Lu Y, Bellis SL, Zhou W, Horvath E, Eklund EA. Identification of a HoxA10 activation domain necessary for transcription of the gene encoding beta3 integrin during myeloid differentiation. The Journal of Biological Chemistry. 282: 16846-59. PMID 17439948 DOI: 10.1074/Jbc.M609744200  0.533
2007 Wang H, Lu Y, Huang W, Papoutsakis ET, Fuhrken P, Eklund EA. HoxA10 activates transcription of the gene encoding mitogen-activated protein kinase phosphatase 2 (Mkp2) in myeloid cells. The Journal of Biological Chemistry. 282: 16164-76. PMID 17430893 DOI: 10.1074/Jbc.M610556200  0.64
2007 Eklund EA. The role of HOX genes in malignant myeloid disease. Current Opinion in Hematology. 14: 85-9. PMID 17255784 DOI: 10.1097/Moh.0B013E32801684B6  0.468
2007 Huang W, Horvath E, Eklund EA. PU.1, interferon regulatory factor (IRF) 2, and the interferon consensus sequence-binding protein (ICSBP/IRF8) cooperate to activate NF1 transcription in differentiating myeloid cells. The Journal of Biological Chemistry. 282: 6629-43. PMID 17200120 DOI: 10.1074/Jbc.M607760200  0.504
2007 Lindsey S, Huang W, Wang H, Horvath E, Zhu C, Eklund EA. Activation of SHP2 protein-tyrosine phosphatase increases HoxA10-induced repression of the genes encoding gp91(PHOX) and p67(PHOX). The Journal of Biological Chemistry. 282: 2237-49. PMID 17138561 DOI: 10.1074/Jbc.M608642200  0.796
2007 Konieczna I, Horvath E, Wang H, Platanias L, Eklund E. ICSBP Haplo-Insufficiency Synergizes with SHP2-Activation for Apoptosis Resistance and Cytokine Hypersensitivity in Myeloid Progenitors. Blood. 110: 2209-2209. DOI: 10.1182/Blood.V110.11.2209.2209  0.794
2006 Huang W, Saberwal G, Horvath E, Zhu C, Lindsey S, Eklund EA. Leukemia-associated, constitutively active mutants of SHP2 protein tyrosine phosphatase inhibit NF1 transcriptional activation by the interferon consensus sequence binding protein. Molecular and Cellular Biology. 26: 6311-32. PMID 16914719 DOI: 10.1128/Mcb.00036-06  0.774
2006 Eklund EA. The role of HOX genes in myeloid leukemogenesis. Current Opinion in Hematology. 13: 67-73. PMID 16456371 DOI: 10.1097/01.Moh.0000208467.63861.D6  0.448
2006 Lindsey S, Wang H, Eklund EA. Leukemia Associated Mutants of SHP2 Protein Tyrosine Phosphatase Prevent HoxA10 Tyrosine Phosphorylation in Differentiating Myeloid Cells, Thereby Blocking Transcription of the Gene Encoding Gp91phox. Blood. 108: 504-504. DOI: 10.1182/Blood.V108.11.504.504  0.803
2006 Huang W, Horvath E, Eklund EA. Leukemia Associated Mutants of SHP2 Protein Tyrosine Phosphatase Inhibit Nf1-Expression by Decreasing ICSBP and IRF2 Phosphorylation. Blood. 108: 1165-1165. DOI: 10.1182/Blood.V108.11.1165.1165  0.559
2005 Lindsey S, Zhu C, Lu YF, Eklund EA. HoxA10 represses transcription of the gene encoding p67phox in phagocytic cells. Journal of Immunology (Baltimore, Md. : 1950). 175: 5269-79. PMID 16210632 DOI: 10.4049/Jimmunol.175.8.5269  0.76
2005 Parmar S, Smith J, Sassano A, Uddin S, Katsoulidis E, Majchrzak B, Kambhampati S, Eklund EA, Tallman MS, Fish EN, Platanias LC. Differential regulation of the p70 S6 kinase pathway by interferon alpha (IFNalpha) and imatinib mesylate (STI571) in chronic myelogenous leukemia cells. Blood. 106: 2436-43. PMID 15790787 DOI: 10.1182/Blood-2004-10-4003  0.455
2005 Bei L, Lu Y, Eklund EA. HOXA9 activates transcription of the gene encoding gp91Phox during myeloid differentiation. The Journal of Biological Chemistry. 280: 12359-70. PMID 15681849 DOI: 10.1074/Jbc.M408138200  0.583
2005 Kakar R, Kautz B, Eklund EA. JAK2 is necessary and sufficient for interferon-gamma-induced transcription of the gene encoding gp91PHOX. Journal of Leukocyte Biology. 77: 120-7. PMID 15496449 DOI: 10.1189/Jlb.0704429  0.512
2005 Lindsey S, Lu Y, Eklund EA. HoxA10 Represses Transcription of Multiple Genes Encoding Respiratory Burst Oxidase Proteins in Undifferentiated Myeloid Cells. Blood. 106: 632-632. DOI: 10.1182/Blood.V106.11.632.632  0.798
2005 Huang W, Saberwal G, Zhu C, Eklund EA. ICSBP Activates Transcription of the Gene Encoding Neurofibromin 1 in Differentiating Myeloid Cells. Blood. 106: 122-122. DOI: 10.1182/Blood.V106.11.122.122  0.589
2004 Zhu C, Saberwal G, Lu Y, Platanias LC, Eklund EA. The interferon consensus sequence-binding protein activates transcription of the gene encoding neurofibromin 1. The Journal of Biological Chemistry. 279: 50874-85. PMID 15371411 DOI: 10.1074/Jbc.M405736200  0.56
2004 Eklund EA, Bei L, Lu Y. HoxA9 Activates Transcription of the Gene Encoding Gp91phox, a Respiratory Burst Oxidase Protein, during Myeloid Differentiation. Blood. 104: 1470-1470. DOI: 10.1182/Blood.V104.11.1470.1470  0.501
2003 Lu Y, Goldenberg I, Bei L, Andrejic J, Eklund EA. HoxA10 represses gene transcription in undifferentiated myeloid cells by interaction with histone deacetylase 2. The Journal of Biological Chemistry. 278: 47792-802. PMID 14512427 DOI: 10.1074/Jbc.M305885200  0.532
2002 Eklund EA, Goldenberg I, Lu Y, Andrejic J, Kakar R. SHP1 protein-tyrosine phosphatase regulates HoxA10 DNA binding and transcriptional repression activity in undifferentiated myeloid cells. The Journal of Biological Chemistry. 277: 36878-88. PMID 12145285 DOI: 10.1074/jbc.M203917200  0.399
2001 Miller KA, Eklund EA, Peddinghaus ML, Cao Z, Fernandes N, Turk PW, Thimmapaya B, Weitzman SA. Kruppel-like factor 4 regulates laminin alpha 3A expression in mammary epithelial cells. The Journal of Biological Chemistry. 276: 42863-8. PMID 11551969 DOI: 10.1074/Jbc.M108130200  0.409
2001 Kautz B, Kakar R, David E, Eklund EA. SHP1 protein-tyrosine phosphatase inhibits gp91PHOX and p67PHOX expression by inhibiting interaction of PU.1, IRF1, interferon consensus sequence-binding protein, and CREB-binding protein with homologous Cis elements in the CYBB and NCF2 genes. The Journal of Biological Chemistry. 276: 37868-78. PMID 11483597 DOI: 10.1074/Jbc.M103381200  0.569
2000 Eklund EA, Jalava A, Kakar R. Tyrosine phosphorylation of HoxA10 decreases DNA binding and transcriptional repression during interferon gamma -induced differentiation of myeloid leukemia cell lines. The Journal of Biological Chemistry. 275: 20117-26. PMID 10766757 DOI: 10.1074/JBC.M907915199  0.399
1998 Eklund EA, Jalava A, Kakar R. PU.1, interferon regulatory factor 1, and interferon consensus sequence-binding protein cooperate to increase gp91(phox) expression. The Journal of Biological Chemistry. 273: 13957-65. PMID 9593745 DOI: 10.1074/JBC.273.22.13957  0.369
1997 Eklund EA, Kakar R. Identification and characterization of TF1(phox), a DNA-binding protein that increases expression of gp91(phox) in PLB985 myeloid leukemia cells. The Journal of Biological Chemistry. 272: 9344-55. PMID 9083071 DOI: 10.1074/jbc.272.14.9344  0.389
1995 Eklund EA, Skalnik DG. Characterization of a gp91-phox promoter element that is required for interferon γ-induced transcription Journal of Biological Chemistry. 270: 8267-8273. PMID 7713934 DOI: 10.1074/Jbc.270.14.8267  0.336
1994 Newburger PE, Skalnik DG, Hopkins PJ, Eklund EA, Curnutte JT. Mutations in the promoter region of the gene for gp91-phox in X-linked chronic granulomatous disease with decreased expression of cytochrome b558 Journal of Clinical Investigation. 94: 1205-1211. PMID 8083361 DOI: 10.1172/Jci117437  0.303
Low-probability matches (unlikely to be authored by this person)
2010 Eklund EA, Raychaudhuri P, Platanias LC. Correlation between IDH2 mutations and disease status in acute myeloid leukemia. Leukemia & Lymphoma. 51: 2157-8. PMID 20929316 DOI: 10.3109/10428194.2010.525271  0.298
2022 Hasan S, Hu L, Williams O, Eklund EA. Ruxolitinib ameliorates progressive anemia and improves survival during episodes of emergency granulopoiesis in Fanconi C mice. Experimental Hematology. PMID 35278531 DOI: 10.1016/j.exphem.2022.03.001  0.291
2022 Willis A, Corey SJ, Murga-Zamalloa C, Karimi S, Khaddour K, Quigley JG, Eklund EA, Chen Y. Dynamin-2 deficiency causes age- and sex-dependent neutropenia and myelodysplasia in mice. Blood Advances. PMID 36417761 DOI: 10.1182/bloodadvances.2022008135  0.25
2017 Williams O, Hjort E, Bei L, Hu L, Eklund EA. Tumor Suppressor, NORE1A (RASSF5), Is an Icsbp-Dependent Inhibitor of Aberrant Stress Granulopoiesis Blood. 130: 4175-4175. DOI: 10.1182/Blood.V130.Suppl_1.4175.4175  0.225
2002 Semel AC, Seales EC, Singhal A, Eklund EA, Colley KJ, Bellis SL. Hyposialylation of integrins stimulates the activity of myeloid fibronectin receptors. The Journal of Biological Chemistry. 277: 32830-6. PMID 12091385 DOI: 10.1074/Jbc.M202493200  0.224
2012 Kipp JL, Lambert-Messerlian G, Eklund E, Rodriguez G, Demczuk M, Gundogan F. Expression of transcription factors controlling alpha inhibin gene expression in placental tissues from pregnancies affected by fetal Down syndrome. Prenatal Diagnosis. 32: 302-5. PMID 22430733 DOI: 10.1002/pd.3826  0.214
2004 Platanias LC, Eklund EA. Hematology grants workshop. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 473-80. PMID 15561699 DOI: 10.1182/Asheducation-2004.1.473  0.194
1995 Eklund EA, Lee Sw, Skalnik DG. Cloning of a cDNA encoding a human DNA-binding protein similar to ribosomal protein S1 Gene. 155: 231-235. PMID 7721096 DOI: 10.1016/0378-1119(94)00898-3  0.186
2021 Youn M, Smith SM, Lee AG, Chae HD, Spiteri E, Erdmann J, Galperin I, Jones LM, Donato M, Abidi P, Bittencourt H, Lacayo N, Dahl G, Aftandilian C, Davis KL, ... ... Eklund E, et al. Comparison of the Transcriptomic Signatures in Pediatric and Adult CML. Cancers. 13. PMID 34944883 DOI: 10.3390/cancers13246263  0.186
2009 Eklund EA, Platanias LC. Screening for microRNAs in myelodysplastic syndromes. Leukemia & Lymphoma. 50: 1735-6. PMID 19883302 DOI: 10.3109/10428190903267567  0.185
2013 Simon MA, Nonzee NJ, McKoy JM, Liu D, Luu TH, Byer P, Eklund EA, Richey EA, Wu Z, Dong X, Rademaker AW. Navigating veterans with an abnormal prostate cancer screening test: a quasi-experimental study. Bmc Health Services Research. 13: 314. PMID 23947435 DOI: 10.1186/1472-6963-13-314  0.183
2009 Eklund EA. Thrombocytopenia and cancer. Cancer Treatment and Research. 148: 279-93. PMID 19377930 DOI: 10.1007/978-0-387-79962-9_16  0.177
2007 Lambert-Messerlian G, Eklund E, Pinar H, Tantravahi U, Schneyer AL. Activin subunit and receptor expression in normal and cleft human fetal palate tissues. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. 10: 436-45. PMID 18001154 DOI: 10.2350/06-05-0087.1  0.171
2003 Tomblyn M, Guo R, Paniagua M, Eklund E, Goolsby C, Papoutsakis E, Miller W, Winter J. 247Ex vivo expanded (EYE) peripheral blood progenitor cells (PBPC) demonstrate respiratory burst(RB) and phagocytic capacity: A flow cytometric analysis Biology of Blood and Marrow Transplantation. 9: 135. DOI: 10.1016/S1083-8791(03)80232-X  0.155
2017 Moore RG, Plante B, Hartnett E, Mitchel J, Raker CA, Vitek W, Eklund E, Lambert-Messerlian G. Assessment of serum HE4 levels throughout the normal menstrual cycle. American Journal of Obstetrics and Gynecology. PMID 28237871 DOI: 10.1016/j.ajog.2017.02.029  0.108
2019 Haddow JE, Metzger BE, Lambert-Messerlian G, Eklund E, Coustan D, Catalano P, Palomaki GE. Maternal BMI, Peripheral Deiodinase Activity, and Plasma Glucose: Relationships among Caucasian Women in the HAPO Study. The Journal of Clinical Endocrinology and Metabolism. PMID 30753726 DOI: 10.1210/jc.2018-02328  0.096
1991 Eklund E, Miller ME, Ansari R, Fisher WB, Einhorn LH. Phase II trial of high-dose cisplatin plus etoposide plus vinblastine in non-small-cell lung cancer. A Hoosier Oncology Group study. American Journal of Clinical Oncology. 14: 412-5. PMID 1659175 DOI: 10.1097/00000421-199110000-00010  0.089
2017 Haddow JE, Lambert-Messerlian G, Eklund E, Neveux LM, Palomaki GE. Peripheral deiodinase activity: A potential explanation for the association between maternal weight and gestational hyperglycemia. Obstetric Medicine. 11: 73-78. PMID 29997689 DOI: 10.1177/1753495X17733223  0.073
1991 Eklund EA, Gabig TG. Deactivation of the subcellular NADPH oxidase and its relationship to termination of the respiratory burst. Biochemical Society Transactions. 19: 51-4. PMID 1645315 DOI: 10.1042/bst0190051  0.062
2019 Dondik Y, Pagidas K, Eklund E, Ngo C, Palomaki GE, Lambert-Messerlian G. Levels of angiogenic markers in second-trimester maternal serum from in vitro fertilization pregnancies with oocyte donation. Fertility and Sterility. 112: 1112-1117. PMID 31843087 DOI: 10.1016/j.fertnstert.2019.07.017  0.059
2021 Blackman A, Mitchell J, Rowswell-Turner R, Singh R, Kim KK, Eklund E, Skates S, Bast RC, Messerlian G, Miller MC, Moore RG. Analysis of serum HE4 levels in various histologic subtypes of epithelial ovarian cancer and other malignant tumors. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 43: 355-365. PMID 34957977 DOI: 10.3233/TUB-211546  0.058
2016 Sevick M, Eklund E, Mensch A, Foreman M, Standeven J, Engsberg J. Using Free Internet Videogames in Upper Extremity Motor Training for Children with Cerebral Palsy. Behavioral Sciences (Basel, Switzerland). 6. PMID 27338485 DOI: 10.3390/bs6020010  0.048
2019 Ahmed S, Eklund E. Rural Accessibility, Rural Development, and Natural Disasters in Bangladesh Journal of Developing Societies. 35: 391-411. DOI: 10.1177/0169796X19868318  0.048
1991 Lapiano‐Smith DA, Eklund EA, Himpsel FJ, Terminello LJ. Epitaxy of LiF on Ge(100) Applied Physics Letters. 59: 2174-2176. DOI: 10.1063/1.106091  0.036
2018 Salameh M, Lee J, Palomaki G, Eklund E, Curran P, Suarez JAR, Lambert-Messerlian G, Bourjeily G. Snoring and markers of fetal and placental wellbeing. Clinica Chimica Acta; International Journal of Clinical Chemistry. PMID 29958890 DOI: 10.1016/j.cca.2018.06.039  0.036
1990 Bales GS, Bruinsma R, Eklund EA, Karunasiri RP, Rudnick J, Zangwill A. Growth and erosion of thin solid films. Science (New York, N.Y.). 249: 264-8. PMID 17750110 DOI: 10.1126/Science.249.4966.264  0.025
2016 Farina A, Eklund E, Bernabini D, Paladino M, Righetti F, Monti G, Lambert-Messerlian G. A First-Trimester Biomarker Panel for Predicting the Development of Gestational Diabetes. Reproductive Sciences (Thousand Oaks, Calif.). 24: 954-959. PMID 27837083 DOI: 10.1177/1933719116675057  0.023
2018 Eklund E. Water: Abundance, Scarcity, and Security in the Age of Humanity. Jeremy J. Schmidt. New York, NY: New York University Press, 2017. xii + 308 pp. (Cloth US$35.00; EBook prices vary by vendor) Transforming Anthropology. 26: 202-204. DOI: 10.1111/traa.12138  0.019
2017 Rehfeldt M, Eklund E, Struck J, Sparwasser A, O'Brien B, Palomaki GE, Köhrle J, Bergmann A, Lambert-Messerlian G. Relaxin-2 connecting peptide (pro-RLX2) levels in second trimester serum samples to predict preeclampsia. Pregnancy Hypertension. PMID 29133069 DOI: 10.1016/J.Preghy.2017.11.001  0.014
2018 EKLUND E. El Mall: The Spatial and Class Politics of Shopping Malls in Latin America. Arlene Dávila. Oakland, CA: University of California Press, 2016, 248 pp. City & Society. 30. DOI: 10.1111/ciso.12161  0.01
2017 Khan N, Lambert-Messerlian G, Monteiro JF, Hodosy J, Tóthová Ľ, Celec P, Eklund E, Curran P, Bourjeily G. Oxidative and carbonyl stress in pregnant women with obstructive sleep apnea. Sleep & Breathing = Schlaf & Atmung. PMID 28236270 DOI: 10.1007/s11325-017-1475-8  0.01
2007 Lambert-Messerlian G, Bandera C, Eklund E, Neuhauser A, Canick J. Very high inhibin A concentration attributed to heterophilic antibody interference. Clinical Chemistry. 53: 800-1. PMID 17405952 DOI: 10.1373/clinchem.2006.082735  0.01
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