Kay-Uwe Wagner - Publications

Affiliations: 
University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Cell Biology, Oncology

82 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Bannoura SF, Aboukameel A, Khan HY, Uddin MH, Jang H, Beal E, Thangasamy A, Kim S, Wagner KU, Mohammad R, Al-Hallak MN, Pasche BC, Azmi AS. Regulator of Chromosome Condensation (RCC1) a novel therapeutic target in pancreatic ductal adenocarcinoma drives tumor progression via the c-Myc-RCC1-Ran axis. Biorxiv : the Preprint Server For Biology. PMID 38187605 DOI: 10.1101/2023.12.18.572102  0.37
2023 Wicker MN, Wagner KU. Cellular Plasticity in Mammary Gland Development and Breast Cancer. Cancers. 15. PMID 38067308 DOI: 10.3390/cancers15235605  0.363
2023 Jacob JB, Wei KC, Bepler G, Reyes JD, Cani A, Polin L, White K, Kim S, Viola N, McGrath J, Guastella A, Yin C, Mi QS, Kidder BL, Wagner KU, et al. Identification of actionable targets for breast cancer intervention using a diversity outbred mouse model. Iscience. 26: 106320. PMID 36968078 DOI: 10.1016/j.isci.2023.106320  0.35
2022 Mohapatra BC, Mirza S, Bele A, Gurumurthy CB, Raza M, Saleem I, Storck MD, Sarkar A, Kollala SS, Shukla SK, Southekal S, Wagner KU, Qiu F, Lele SM, Alsaleem MA, et al. Ecdysoneless overexpression drives mammary tumorigenesis through upregulation of c-MYC and glucose metabolism. Molecular Cancer Research : McR. PMID 35675041 DOI: 10.1158/1541-7786.MCR-22-0122  0.354
2021 Rädler PD, Vistisen K, Triplett AA, Dennaoui R, Li Y, Shrestha H, Ferraiuolo RM, Thangasamy A, Saur D, Wagner KU. Dual recombinase action in the normal and neoplastic mammary gland epithelium. Scientific Reports. 11: 20775. PMID 34675248 DOI: 10.1038/s41598-021-00231-8  0.483
2021 Dennaoui R, Shrestha H, Wagner KU. Models of pancreatic ductal adenocarcinoma. Cancer Metastasis Reviews. PMID 34491463 DOI: 10.1007/s10555-021-09989-9  0.326
2021 Lyu C, Ye Y, Lensing MM, Wagner KU, Weigel RJ, Chen S. Targeting Gi/o protein-coupled receptor signaling blocks HER2-induced breast cancer development and enhances HER2-targeted therapy. Jci Insight. PMID 34343132 DOI: 10.1172/jci.insight.150532  0.309
2021 Rädler PD, Wehde BL, Triplett AA, Shrestha H, Shepherd JH, Pfefferle AD, Rui H, Cardiff RD, Perou CM, Wagner KU. Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells. Nature Communications. 12: 3742. PMID 34145248 DOI: 10.1038/s41467-021-23957-5  0.436
2020 Tarang S, Pyakurel U, Weston MD, Vijayakumar S, Jones T, Wagner KU, Rocha-Sanchez SM. Spatiotemporally controlled overexpression of cyclin D1 triggers generation of supernumerary cells in the postnatal mouse inner ear. Hearing Research. 390: 107951. PMID 32244147 DOI: 10.1016/j.heares.2020.107951  0.352
2020 Ferraiuolo RM, Manthey KC, Stanton MJ, Triplett AA, Wagner KU. The Multifaceted Roles of the Tumor Susceptibility Gene 101 (TSG101) in Normal Development and Disease. Cancers. 12. PMID 32075127 DOI: 10.3390/Cancers12020450  0.783
2020 Sakamoto K, Rädler PD, Wehde BL, Triplett AA, Shrestha H, Ferraiuolo RM, Amari F, Coppola V, Klinakis A, Efstratiadis A, Wagner KU. Efficient tissue-type specific expression of target genes in a tetracycline-controlled manner from the ubiquitously active Eef1a1 locus. Scientific Reports. 10: 207. PMID 31937792 DOI: 10.1038/S41598-019-57052-Z  0.496
2019 Essandoh K, Deng S, Wang X, Jiang M, Mu X, Peng J, Li Y, Peng T, Wagner KU, Rubinstein J, Fan GC. Tsg101 positively regulates physiologic-like cardiac hypertrophy through FIP3-mediated endosomal recycling of IGF-1R. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802338RR. PMID 30884248 DOI: 10.1096/Fj.201802338Rr  0.337
2018 Wehde BL, Rädler PD, Shrestha H, Johnson SJ, Triplett AA, Wagner KU. Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression. Cell Reports. 25: 2192-2207.e5. PMID 30463015 DOI: 10.1016/J.Celrep.2018.10.063  0.537
2017 Zboray K, Mohrherr J, Stiedl P, Pranz K, Wandruszka L, Grabner B, Eferl R, Moriggl R, Stoiber D, Sakamoto K, Wagner KU, Popper H, Casanova E, Moll HP. AKT3 drives adenoid cystic carcinoma development in salivary glands. Cancer Medicine. PMID 29282901 DOI: 10.1002/Cam4.1293  0.35
2017 Rädler PD, Wehde BL, Wagner KU. Crosstalk between STAT5 activation and PI3K/AKT functions in normal and transformed mammary epithelial cells. Molecular and Cellular Endocrinology. PMID 28495456 DOI: 10.1016/j.mce.2017.04.025  0.414
2017 Rajbhandari N, Lin WC, Wehde BL, Triplett AA, Wagner KU. Autocrine IGF1 Signaling Mediates Pancreatic Tumor Cell Dormancy in the Absence of Oncogenic Drivers. Cell Reports. 18: 2243-2255. PMID 28249168 DOI: 10.1016/j.celrep.2017.02.013  0.77
2016 Mukhopadhyay C, Triplett A, Bargar T, Heckman C, Wagner KU, Naramura M. Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27930322 DOI: 10.1073/Pnas.1615677113  0.453
2016 Sakamoto K, Wehde BL, Rädler PD, Triplett AA, Wagner KU. Generation of Janus kinase 1 (JAK1) conditional knockout mice. Genesis (New York, N.Y. : 2000). PMID 27671227 DOI: 10.1002/dvg.22982  0.388
2016 Sakamoto K, Wehde BL, Yoo KH, Kim T, Rajbhandari N, Shin HY, Triplett AA, Rädler PD, Schuler F, Villunger A, Kang K, Hennighausen L, Wagner KU. Janus kinase 1 is essential for inflammatory cytokine signaling and mammary gland remodeling. Molecular and Cellular Biology. PMID 27044867 DOI: 10.1128/Mcb.00999-15  0.409
2015 Sánchez-Bailón MP, Calcabrini A, Mayoral-Varo V, Molinari A, Wagner KU, Losada JP, Ciordia S, Albar JP, Martín-Pérez J. Cyr61 as mediator of Src signaling in triple negative breast cancer cells. Oncotarget. 6: 13520-38. PMID 25980494  0.365
2015 Witkiewicz AK, McMillan EA, Balaji U, Baek G, Lin WC, Mansour J, Mollaee M, Wagner KU, Koduru P, Yopp A, Choti MA, Yeo CJ, McCue P, White MA, Knudsen ES. Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets. Nature Communications. 6: 6744. PMID 25855536 DOI: 10.1038/ncomms7744  0.69
2015 Das S, Rachagani S, Torres-Gonzalez MP, Lakshmanan I, Majhi PD, Smith LM, Wagner KU, Batra SK. Carboxyl-terminal domain of MUC16 imparts tumorigenic and metastatic functions through nuclear translocation of JAK2 to pancreatic cancer cells. Oncotarget. 6: 5772-87. PMID 25691062 DOI: 10.18632/Oncotarget.3308  0.371
2015 Joshi S, Kumar S, Bafna S, Rachagani S, Wagner KU, Jain M, Batra SK. Genetically engineered mucin mouse models for inflammation and cancer. Cancer Metastasis Reviews. PMID 25634251 DOI: 10.1007/S10555-015-9549-1  0.345
2014 Akada H, Akada S, Hutchison RE, Sakamoto K, Wagner KU, Mohi G. Critical role of Jak2 in the maintenance and function of adult hematopoietic stem cells. Stem Cells (Dayton, Ohio). 32: 1878-89. PMID 24677703 DOI: 10.1002/stem.1711  0.367
2014 Lin WC, Rajbhandari N, Wagner KU. Cancer cell dormancy in novel mouse models for reversible pancreatic cancer: a lingering challenge in the development of targeted therapies. Cancer Research. 74: 2138-43. PMID 24670819 DOI: 10.1158/0008-5472.CAN-13-3437  0.755
2014 Schmidt JW, Wehde BL, Sakamoto K, Triplett AA, West WW, Wagner KU. Novel transcripts from a distinct promoter that encode the full-length AKT1 in human breast cancer cells. Bmc Cancer. 14: 195. PMID 24628780 DOI: 10.1186/1471-2407-14-195  0.461
2014 Schmidt JW, Wehde BL, Sakamoto K, Triplett AA, Anderson SM, Tsichlis PN, Leone G, Wagner KU. Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis. Molecular and Cellular Biology. 34: 1363-77. PMID 24469394 DOI: 10.1128/Mcb.01220-13  0.48
2014 Zhang Q, Sakamoto K, Wagner KU. D-type Cyclins are important downstream effectors of cytokine signaling that regulate the proliferation of normal and neoplastic mammary epithelial cells. Molecular and Cellular Endocrinology. 382: 583-92. PMID 23562856 DOI: 10.1016/j.mce.2013.03.016  0.416
2014 Themanns M, Friedbichler K, Kessler SM, Schlederer M, Kenner L, Wagner K, Haybaeck J, Moriggl R. Abstract 108: Consequences of hepatic JAK2 deficiency for liver metabolism and hepatocarcinogenesis Cancer Research. 74: 108-108. DOI: 10.1158/1538-7445.Am2014-108  0.311
2013 Yang P, Zhang Y, Pang J, Zhang S, Yu Q, He L, Wagner KU, Zhou Z, Wang CY. Loss of Jak2 impairs endothelial function by attenuating Raf-1/MEK1/Sp-1 signaling along with altered eNOS activities. The American Journal of Pathology. 183: 617-25. PMID 23747947 DOI: 10.1016/j.ajpath.2013.04.007  0.315
2013 Lin WC, Schmidt JW, Creamer BA, Triplett AA, Wagner KU. Gain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lung. Plos One. 8: e60902. PMID 23565285 DOI: 10.1371/Journal.Pone.0060902  0.775
2013 Xin H, Lu R, Lee H, Zhang W, Zhang C, Deng J, Liu Y, Shen S, Wagner KU, Forman S, Jove R, Yu H. G-protein-coupled receptor agonist BV8/prokineticin-2 and STAT3 protein form a feed-forward loop in both normal and malignant myeloid cells. The Journal of Biological Chemistry. 288: 13842-9. PMID 23548897 DOI: 10.1074/Jbc.M113.450049  0.446
2013 Lin WC, Rajbhandari N, Liu C, Sakamoto K, Zhang Q, Triplett AA, Batra SK, Opavsky R, Felsher DW, DiMaio DJ, Hollingsworth MA, Morris JP, Hebrok M, Witkiewicz AK, Brody JR, ... ... Wagner KU, et al. Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer. Cancer Research. 73: 1821-30. PMID 23467612 DOI: 10.1158/0008-5472.Can-12-2067  0.77
2012 Rachagani S, Torres MP, Kumar S, Haridas D, Baine M, Macha MA, Kaur S, Ponnusamy MP, Dey P, Seshacharyulu P, Johansson SL, Jain M, Wagner KU, Batra SK. Mucin (Muc) expression during pancreatic cancer progression in spontaneous mouse model: potential implications for diagnosis and therapy. Journal of Hematology & Oncology. 5: 68. PMID 23102107 DOI: 10.1186/1756-8722-5-68  0.452
2012 Sakamoto K, Schmidt JW, Wagner KU. Generation of a novel MMTV-tTA transgenic mouse strain for the targeted expression of genes in the embryonic and postnatal mammary gland. Plos One. 7: e43778. PMID 22952764 DOI: 10.1371/journal.pone.0043778  0.346
2012 Sánchez-Bailón MP, Calcabrini A, Gómez-Domínguez D, Morte B, Martín-Forero E, Gómez-López G, Molinari A, Wagner KU, Martín-Pérez J. Src kinases catalytic activity regulates proliferation, migration and invasiveness of MDA-MB-231 breast cancer cells. Cellular Signalling. 24: 1276-86. PMID 22570868  0.414
2012 Morris CR, Stanton MJ, Manthey KC, Oh KB, Wagner KU. A knockout of the Tsg101 gene leads to decreased expression of ErbB receptor tyrosine kinases and induction of autophagy prior to cell death. Plos One. 7: e34308. PMID 22479596 DOI: 10.1371/Journal.Pone.0034308  0.784
2012 Hantschel O, Warsch W, Eckelhart E, Kaupe I, Grebien F, Wagner KU, Superti-Furga G, Sexl V. BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia. Nature Chemical Biology. 8: 285-93. PMID 22286129 DOI: 10.1038/nchembio.775  0.335
2012 Hlady RA, Novakova S, Opavska J, Klinkebiel D, Peters SL, Bies J, Hannah J, Iqbal J, Anderson KM, Siebler HM, Smith LM, Greiner TC, Bastola D, Joshi S, Lockridge O, ... ... Wagner KU, et al. Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis. The Journal of Clinical Investigation. 122: 163-77. PMID 22133874 DOI: 10.1172/Jci57292  0.319
2012 Lin W, Rajbhandari N, Liu C, Sakamoto K, Batra S, Opavsky R, Felsher D, Hollingsworth M, Hebrok M, Rui H, Wagner K. Abstract LB-429: Dormant cancer cells contribute to residual disease in a mouse model for reversible pancreatic cancer Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-429  0.767
2011 Wagner KU, Schmidt JW. The two faces of Janus kinases and their respective STATs in mammary gland development and cancer. Journal of Carcinogenesis. 10: 32. PMID 22279417 DOI: 10.4103/1477-3163.90677  0.497
2011 Schneckenleithner C, Bago-Horvath Z, Dolznig H, Neugebauer N, Kollmann K, Kolbe T, Decker T, Kerjaschki D, Wagner KU, Müller M, Stoiber D, Sexl V. Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias. Oncotarget. 2: 1043-54. PMID 22185785 DOI: 10.18632/Oncotarget.371  0.521
2011 Zhang Q, Sakamoto K, Liu C, Triplett AA, Lin WC, Rui H, Wagner KU. Cyclin D3 compensates for the loss of cyclin D1 during ErbB2-induced mammary tumor initiation and progression. Cancer Research. 71: 7513-24. PMID 22037875 DOI: 10.1158/0008-5472.Can-11-1783  0.742
2011 Tu C, Ahmad G, Mohapatra B, Bhattacharyya S, Ortega-Cava CF, Chung BM, Wagner KU, Raja SM, Naramura M, Band V, Band H. ESCRT proteins: Double-edged regulators of cellular signaling. Bioarchitecture. 1: 45-48. PMID 21866262 DOI: 10.4161/bioa.1.1.15173  0.348
2011 Pathak S, Ma S, Trinh L, Eudy J, Wagner KU, Joshi SS, Lu R. IRF4 is a suppressor of c-Myc induced B cell leukemia. Plos One. 6: e22628. PMID 21818355 DOI: 10.1371/Journal.Pone.0022628  0.32
2011 Rucker EB, Hale AN, Durtschi DC, Sakamoto K, Wagner KU. Forced involution of the functionally differentiated mammary gland by overexpression of the pro-apoptotic protein bax. Genesis (New York, N.Y. : 2000). 49: 24-35. PMID 21254334 DOI: 10.1002/Dvg.20691  0.365
2011 Lin W, Zhang Q, Opavsky R, DiMaio DJ, Felsher DW, Batra SK, Hollingsworth MA, Wagner K. Abstract 2384: A novel mouse model for the study of c-MYC during initiation and progression of pancreatic ductal adenocarcinoma Cancer Research. 71: 2384-2384. DOI: 10.1158/1538-7445.Am2011-2384  0.769
2011 Zhang Q, Sakamoto K, Triplett AA, Lin W, Creamer BA, Wagner K. Abstract 2379: Cyclin D3 is important for ErbB2-induced mammary cancer initiation and progression in the absence of Cyclin D1 Cancer Research. 71: 2379-2379. DOI: 10.1158/1538-7445.Am2011-2379  0.788
2010 Tu C, Ortega-Cava CF, Winograd P, Stanton MJ, Reddi AL, Dodge I, Arya R, Dimri M, Clubb RJ, Naramura M, Wagner KU, Band V, Band H. Endosomal-sorting complexes required for transport (ESCRT) pathway-dependent endosomal traffic regulates the localization of active Src at focal adhesions. Proceedings of the National Academy of Sciences of the United States of America. 107: 16107-12. PMID 20805499 DOI: 10.1073/Pnas.1009471107  0.77
2010 Sakamoto K, Triplett AA, Schuler LA, Wagner KU. Janus kinase 2 is required for the initiation but not maintenance of prolactin-induced mammary cancer. Oncogene. 29: 5359-69. PMID 20639901 DOI: 10.1038/Onc.2010.274  0.581
2010 Creamer BA, Sakamoto K, Schmidt JW, Triplett AA, Moriggl R, Wagner KU. Stat5 promotes survival of mammary epithelial cells through transcriptional activation of a distinct promoter in Akt1. Molecular and Cellular Biology. 30: 2957-70. PMID 20385773 DOI: 10.1128/Mcb.00851-09  0.806
2010 Zhang Q, Triplett AA, Harms DW, Lin WC, Creamer BA, Rizzino A, Wagner KU. Temporally and spatially controlled expression of transgenes in embryonic and adult tissues. Transgenic Research. 19: 499-509. PMID 19821046 DOI: 10.1007/S11248-009-9329-1  0.767
2010 Hantschel OD, Eckelhart E, Kaupe I, Grebien F, Wagner K, Sexl V, Superti-Furga G. Bcr-Abl Directly Activates Stat5 Independent of Jak2 Blood. 116: 511-511. DOI: 10.1182/Blood.V116.21.511.511  0.458
2009 Sakamoto K, Lin WC, Triplett AA, Wagner KU. Targeting janus kinase 2 in Her2/neu-expressing mammary cancer: Implications for cancer prevention and therapy. Cancer Research. 69: 6642-50. PMID 19638583 DOI: 10.1158/0008-5472.CAN-09-0746  0.803
2009 Creamer BA, Triplett AA, Wagner KU. Longitudinal analysis of mammogenesis using a novel tetracycline-inducible mouse model and in vivo imaging. Genesis (New York, N.Y. : 2000). 47: 234-45. PMID 19208431 DOI: 10.1002/Dvg.20480  0.774
2008 Bierie B, Stover DG, Abel TW, Chytil A, Gorska AE, Aakre M, Forrester E, Yang L, Wagner KU, Moses HL. Transforming growth factor-beta regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment. Cancer Research. 68: 1809-19. PMID 18339861 DOI: 10.1158/0008-5472.Can-07-5597  0.365
2008 Wagner KU, Rui H. Jak2/Stat5 signaling in mammogenesis, breast cancer initiation and progression. Journal of Mammary Gland Biology and Neoplasia. 13: 93-103. PMID 18228120 DOI: 10.1007/S10911-008-9062-Z  0.424
2007 Feng Y, Manka D, Wagner KU, Khan SA. Estrogen receptor-alpha expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 14718-23. PMID 17785410 DOI: 10.1073/Pnas.0706933104  0.337
2007 Neilson LM, Zhu J, Xie J, Malabarba MG, Sakamoto K, Wagner KU, Kirken RA, Rui H. Coactivation of janus tyrosine kinase (Jak)1 positively modulates prolactin-Jak2 signaling in breast cancer: recruitment of ERK and signal transducer and activator of transcription (Stat)3 and enhancement of Akt and Stat5a/b pathways. Molecular Endocrinology (Baltimore, Md.). 21: 2218-32. PMID 17550976 DOI: 10.1210/Me.2007-0173  0.395
2007 Sakamoto K, Creamer BA, Triplett AA, Wagner KU. The Janus kinase 2 is required for expression and nuclear accumulation of cyclin D1 in proliferating mammary epithelial cells. Molecular Endocrinology (Baltimore, Md.). 21: 1877-92. PMID 17519353 DOI: 10.1210/Me.2006-0316  0.788
2007 Oh KB, Stanton MJ, West WW, Todd GL, Wagner KU. Tsg101 is upregulated in a subset of invasive human breast cancers and its targeted overexpression in transgenic mice reveals weak oncogenic properties for mammary cancer initiation. Oncogene. 26: 5950-9. PMID 17369844 DOI: 10.1038/sj.onc.1210401  0.801
2007 Matulka LA, Triplett AA, Wagner KU. Parity-induced mammary epithelial cells are multipotent and express cell surface markers associated with stem cells. Developmental Biology. 303: 29-44. PMID 17222404 DOI: 10.1016/j.ydbio.2006.12.017  0.309
2005 Triplett AA, Sakamoto K, Matulka LA, Shen L, Smith GH, Wagner KU. Expression of the whey acidic protein (Wap) is necessary for adequate nourishment of the offspring but not functional differentiation of mammary epithelial cells. Genesis (New York, N.Y. : 2000). 43: 1-11. PMID 16106354 DOI: 10.1002/gene.20149  0.323
2005 Sum EY, Shackleton M, Hahm K, Thomas RM, O'Reilly LA, Wagner KU, Lindeman GJ, Visvader JE. Loss of the LIM domain protein Lmo4 in the mammary gland during pregnancy impedes lobuloalveolar development. Oncogene. 24: 4820-8. PMID 15856027 DOI: 10.1038/Sj.Onc.1208638  0.333
2004 Sgagias MK, Wagner KU, Hamik B, Stoeger S, Spieker R, Huber LJ, Chodosh LA, Cowan KH. Brca1-deficient murine mammary epithelial cells have increased sensitivity to CDDP and MMS. Cell Cycle (Georgetown, Tex.). 3: 1451-6. PMID 15492509 DOI: 10.4161/Cc.3.11.1211  0.321
2004 Krempler A, Qi Y, Triplett AA, Zhu J, Rui H, Wagner KU. Generation of a conditional knockout allele for the Janus kinase 2 (Jak2) gene in mice. Genesis (New York, N.Y. : 2000). 40: 52-7. PMID 15354294 DOI: 10.1002/Gene.20063  0.32
2004 Henry MD, Triplett AA, Oh KB, Smith GH, Wagner KU. Parity-induced mammary epithelial cells facilitate tumorigenesis in MMTV-neu transgenic mice. Oncogene. 23: 6980-5. PMID 15286714 DOI: 10.1038/sj.onc.1207827  0.403
2004 Wagner KU, Krempler A, Triplett AA, Qi Y, George NM, Zhu J, Rui H. Impaired alveologenesis and maintenance of secretory mammary epithelial cells in Jak2 conditional knockout mice Molecular and Cellular Biology. 24: 5510-5520. PMID 15169911 DOI: 10.1128/Mcb.24.12.5510-5520.2004  0.4
2004 Cheung AM, Elia A, Tsao MS, Done S, Wagner KU, Hennighausen L, Hakem R, Mak TW. Brca2 deficiency does not impair mammary epithelium development but promotes mammary adenocarcinoma formation in p53(+/-) mutant mice. Cancer Research. 64: 1959-65. PMID 15026330 DOI: 10.1158/0008-5472.Can-03-2270  0.355
2003 Long W, Wagner KU, Lloyd KC, Binart N, Shillingford JM, Hennighausen L, Jones FE. Impaired differentiation and lactational failure of Erbb4-deficient mammary glands identify ERBB4 as an obligate mediator of STAT5. Development (Cambridge, England). 130: 5257-68. PMID 12954715 DOI: 10.1242/dev.00715  0.41
2003 Wagner KU, Krempler A, Qi Y, Park K, Henry MD, Triplett AA, Riedlinger G, Rucker III EB, Hennighausen L. Tsg101 is essential for cell growth, proliferation, and cell survival of embryonic and adult tissues. Molecular and Cellular Biology. 23: 150-62. PMID 12482969 DOI: 10.1128/Mcb.23.1.150-162.2003  0.395
2002 Krempler A, Henry MD, Triplett AA, Wagner KU. Targeted deletion of the Tsg101 gene results in cell cycle arrest at G1/S and p53-independent cell death. The Journal of Biological Chemistry. 277: 43216-23. PMID 12205095 DOI: 10.1074/jbc.M207662200  0.405
2002 Li G, Robinson GW, Lesche R, Martinez-Diaz H, Jiang Z, Rozengurt N, Wagner KU, Wu DC, Lane TF, Liu X, Hennighausen L, Wu H. Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland. Development (Cambridge, England). 129: 4159-70. PMID 12163417  0.392
2002 Nevalainen MT, Xie J, Bubendorf L, Wagner KU, Rui H. Basal activation of transcription factor signal transducer and activator of transcription (Stat5) in nonpregnant mouse and human breast epithelium. Molecular Endocrinology (Baltimore, Md.). 16: 1108-24. PMID 11981045 DOI: 10.1210/Mend.16.5.0839  0.372
2002 Cui Y, Miyoshi K, Claudio E, Siebenlist UK, Gonzalez FJ, Flaws J, Wagner KU, Hennighausen L. Loss of the peroxisome proliferation-activated receptor gamma (PPARgamma ) does not affect mammary development and propensity for tumor formation but leads to reduced fertility. The Journal of Biological Chemistry. 277: 17830-5. PMID 11884400 DOI: 10.1074/Jbc.M200186200  0.349
2001 Wagner KU, McAllister K, Ward T, Davis B, Wiseman R, Hennighausen L. Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice. Transgenic Research. 10: 545-53. PMID 11817542 DOI: 10.1023/A:1013063514007  0.399
2001 Miyoshi K, Shillingford JM, Smith GH, Grimm SL, Wagner KU, Oka T, Rosen JM, Robinson GW, Hennighausen L. Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium. The Journal of Cell Biology. 155: 531-42. PMID 11706048 DOI: 10.1083/Jcb.200107065  0.457
2001 Robinson GW, Wagner KU, Hennighausen L. Functional mammary gland development and oncogene-induced tumor formation are not affected by the absence of the retinoblastoma gene. Oncogene. 20: 7115-9. PMID 11704837 DOI: 10.1038/Sj.Onc.1204888  0.464
1998 Wagner KU, Dierisseau P, Rucker EB, Robinson GW, Hennighausen L. Genomic architecture and transcriptional activation of the mouse and human tumor susceptibility gene TSG101: common types of shorter transcripts are true alternative splice variants. Oncogene. 17: 2761-70. PMID 9840940 DOI: 10.1038/sj.onc.1202529  0.306
1997 Hennighausen L, Robinson GW, Wagner KU, Liu X. Developing a mammary gland is a stat affair. Journal of Mammary Gland Biology and Neoplasia. 2: 365-72. PMID 10935024 DOI: 10.1023/A:1026347313096  0.364
1997 Li M, Liu X, Robinson G, Bar-Peled U, Wagner KU, Young WS, Hennighausen L, Furth PA. Mammary-derived signals activate programmed cell death during the first stage of mammary gland involution. Proceedings of the National Academy of Sciences of the United States of America. 94: 3425-30. PMID 9096410 DOI: 10.1073/Pnas.94.7.3425  0.381
1996 Young WS, Shepard E, Amico J, Hennighausen L, Wagner KU, LaMarca ME, McKinney C, Ginns EI. Deficiency in mouse oxytocin prevents milk ejection, but not fertility or parturition. Journal of Neuroendocrinology. 8: 847-53. PMID 8933362 DOI: 10.1046/J.1365-2826.1996.05266.X  0.319
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