Benjamin A. Alman - Publications

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
Molecular Biology

109 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Yahara Y, Barrientos T, Tang YJ, Puviindran V, Nadesan P, Zhang H, Gibson JR, Gregory SG, Diao Y, Xiang Y, Qadri YJ, Souma T, Shinohara ML, Alman BA. Erythromyeloid progenitors give rise to a population of osteoclasts that contribute to bone homeostasis and repair. Nature Cell Biology. 22: 49-59. PMID 31907410 DOI: 10.1038/S41556-019-0437-8  0.32
2019 Tang YJ, Huang J, Tsushima H, Ban GI, Zhang H, Oristian KM, Puviindran V, Williams N, Ding X, Ou J, Jung SH, Lee CL, Jiao Y, Chen BJ, Kirsch DG, ... Alman BA, et al. Tracing Tumor Evolution in Sarcoma Reveals Clonal Origin of Advanced Metastasis. Cell Reports. 28: 2837-2850.e5. PMID 31509746 DOI: 10.1016/J.Celrep.2019.08.029  0.34
2019 Zhang H, Wei Q, Tsushima H, Puviindran V, Tang YJ, Pathmanapan S, Poon R, Ramu E, Al-Jazrawe M, Wunder JS, Alman BA. Intracellular cholesterol biosynthesis in enchondroma and chondrosarcoma. Jci Insight. 5. PMID 31039139 DOI: 10.1172/Jci.Insight.127232  0.357
2019 Ali SA, Niu B, Cheah KSE, Alman B. Unique and overlapping GLI1 and GLI2 transcriptional targets in neoplastic chondrocytes. Plos One. 14: e0211333. PMID 30695055 DOI: 10.1371/Journal.Pone.0211333  0.362
2018 Vi L, Baht GS, Soderblom EJ, Whetstone H, Wei Q, Furman B, Puviindran V, Nadesan P, Foster M, Poon R, White JP, Yahara Y, Ng A, Barrientos T, Grynpas M, ... ... Alman BA, et al. Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in mice. Nature Communications. 9: 5191. PMID 30518764 DOI: 10.1038/S41467-018-07666-0  0.322
2018 Tsushima H, Tang YJ, Puviindran V, Hsu SC, Nadesan P, Yu C, Zhang H, Mirando AJ, Hilton MJ, Alman BA. Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis. Development (Cambridge, England). PMID 29899135 DOI: 10.1242/Dev.162396  0.733
2018 Mercier KA, Al-Jazrawe M, Poon R, Acuff Z, Alman B. A Metabolomics Pilot Study on Desmoid Tumors and Novel Drug Candidates. Scientific Reports. 8: 584. PMID 29330550 DOI: 10.1038/S41598-017-18921-7  0.387
2018 Tang J, David K, Alman B. Abstract IA13: Dynamic cell populations are responsible for sarcoma propagating potential Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Sarcomas17-Ia13  0.352
2018 Seto A, Gokgoz N, Wei Q, Babichev Y, Dickson BC, Alman B, Gladdy RA, Shlien A, Wunder J, Andrulis IL. Abstract A04: Molecular characterization of undifferentiated pleomorphic sarcomas Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Sarcomas17-A04  0.339
2017 Hsu SC, Nadesan P, Puviindran V, Stallcup WB, Kirsch DG, Alman BA. Effects of chondroitin sulfate proteoglycan 4 (NG2/CSPG4) on soft tissue sarcoma growth depend on tumor developmental stage. The Journal of Biological Chemistry. PMID 29196603 DOI: 10.1074/Jbc.M117.805051  0.732
2017 Baht GS, Nadesan P, Silkstone D, Alman BA. Pharmacologically targeting beta-catenin for NF1 associated deficiencies in fracture repair. Bone. 98: 31-36. PMID 28254468 DOI: 10.1016/J.Bone.2017.02.012  0.353
2017 Al-Jazrawe M, Xu S, Wei Q, Poon R, Alman B. Abstract 5897: Single cell-derived analysis of desmoid tumors for studying tumor-stroma interactions Cancer Research. 77: 5897-5897. DOI: 10.1158/1538-7445.Am2017-5897  0.383
2016 Sato S, Tang YJ, Wei Q, Hirata M, Weng A, Han I, Okawa A, Takeda S, Whetstone H, Nadesan P, Kirsch DG, Wunder JS, Alman BA. Mesenchymal Tumors Can Derive from Ng2/Cspg4-Expressing Pericytes with β-Catenin Modulating the Neoplastic Phenotype. Cell Reports. PMID 27425618 DOI: 10.1016/J.Celrep.2016.06.058  0.401
2016 Ghadakzadeh S, Kannu P, Whetstone H, Howard A, Alman BA. β-Catenin modulation in neurofibromatosis type 1 bone repair: therapeutic implications. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27306335 DOI: 10.1096/Fj.201500190Rr  0.329
2016 Rockel JS, Yu C, Whetstone H, Craft AM, Reilly K, Ma H, Tsushima H, Puviindran V, Al-Jazrawe M, Keller GM, Alman BA. Hedgehog inhibits β-catenin activity in synovial joint development and osteoarthritis. The Journal of Clinical Investigation. PMID 27018594 DOI: 10.1172/Jci80205  0.363
2015 Gray MJ, Kannu P, Sharma S, Neyt C, Zhang D, Paria N, Daniel PB, Whetstone H, Sprenger HG, Hammerschmidt P, Weng A, Dupuis L, Jobling R, Mendoza-Londono R, Dray M, ... ... Alman BA, et al. Mutations Preventing Regulated Exon Skipping in MET Cause Osteofibrous Dysplasia. American Journal of Human Genetics. 97: 837-47. PMID 26637977 DOI: 10.1016/J.Ajhg.2015.11.001  0.305
2015 Stinson JN, Jibb LA, Nguyen C, Nathan PC, Maloney AM, Dupuis LL, Gerstle JT, Hopyan S, Alman BA, Strahlendorf C, Portwine C, Johnston DL. Construct validity and reliability of a real-time multidimensional smartphone app to assess pain in children and adolescents with cancer. Pain. 156: 2607-2615. PMID 26580680 DOI: 10.1097/J.Pain.0000000000000385  0.586
2015 Wei Q, Tang YJ, Voisin V, Sato S, Hirata M, Whetstone H, Han I, Ailles L, Bader GD, Wunder J, Alman BA. Identification of CD146 as a marker enriched for tumor-propagating capacity reveals targetable pathways in primary human sarcoma. Oncotarget. PMID 26517673 DOI: 10.18632/Oncotarget.5375  0.322
2015 Al-Jazrawe M, Au M, Alman B. Optimal therapy for desmoid tumors: current options and challenges for the future. Expert Review of Anticancer Therapy. 1-16. PMID 26472625 DOI: 10.1586/14737140.2015.1096203  0.331
2015 Ali SA, Al-Jazrawe M, Ma H, Whetstone H, Poon R, Farr S, Naples M, Adeli K, Alman B. Hedgehog signaling regulates cholesterol homeostasis in osteoarthritic cartilage. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26315393 DOI: 10.1002/Art.39337  0.374
2015 Ng AH, Baht GS, Alman BA, Grynpas MD. Bone Marrow Stress Decreases Osteogenic Progenitors. Calcified Tissue International. PMID 26220824 DOI: 10.1007/S00223-015-0032-3  0.302
2015 Alman BA. The role of hedgehog signalling in skeletal health and disease. Nature Reviews. Rheumatology. 11: 552-60. PMID 26077918 DOI: 10.1038/Nrrheum.2015.84  0.395
2015 Baht GS, Silkstone D, Vi L, Nadesan P, Amani Y, Whetstone H, Wei Q, Alman BA. Exposure to a youthful circulaton rejuvenates bone repair through modulation of β-catenin. Nature Communications. 6: 7131. PMID 25988592 DOI: 10.1038/Ncomms8131  0.333
2015 Craft AM, Rockel JS, Nartiss Y, Kandel RA, Alman BA, Keller GM. Generation of articular chondrocytes from human pluripotent stem cells. Nature Biotechnology. 33: 638-45. PMID 25961409 DOI: 10.1038/Nbt.3210  0.331
2015 Hirata M, Sasaki M, Cairns RA, Inoue S, Puviindran V, Li WY, Snow BE, Jones LD, Wei Q, Sato S, Tang YJ, Nadesan P, Rockel J, Whetstone H, Poon R, ... ... Alman BA, et al. Mutant IDH is sufficient to initiate enchondromatosis in mice. Proceedings of the National Academy of Sciences of the United States of America. 112: 2829-34. PMID 25730874 DOI: 10.1073/Pnas.1424400112  0.361
2015 Vi L, Baht GS, Whetstone H, Ng A, Wei Q, Poon R, Mylvaganam S, Grynpas M, Alman BA. Macrophages promote osteoblastic differentiation in-vivo: implications in fracture repair and bone homeostasis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 1090-102. PMID 25487241 DOI: 10.1002/Jbmr.2422  0.311
2014 Zhukova N, Ramaswamy V, Remke M, Martin DC, Castelo-Branco P, Zhang CH, Fraser M, Tse K, Poon R, Shih DJ, Baskin B, Ray PN, Bouffet E, Dirks P, von Bueren AO, ... ... Alman B, et al. WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma. Acta Neuropathologica Communications. 2: 174. PMID 25539912 DOI: 10.1186/S40478-014-0174-Y  0.304
2014 Gordon JA, Lisle JW, Alman BA, Lian JB. Disruption of crosstalk between mesenchymal stromal and tumor cells in bone marrow as a therapeutic target to prevent metastatic bone disease. Journal of Cellular Physiology. 229: 1884-6. PMID 24905746 DOI: 10.1002/Jcp.24692  0.37
2014 Amini-Nik S, Cambridge E, Yu W, Guo A, Whetstone H, Nadesan P, Poon R, Hinz B, Alman BA. β-Catenin-regulated myeloid cell adhesion and migration determine wound healing. The Journal of Clinical Investigation. 124: 2599-610. PMID 24837430 DOI: 10.1172/Jci62059  0.349
2014 Campbell VT, Nadesan P, Ali SA, Wang CY, Whetstone H, Poon R, Wei Q, Keilty J, Proctor J, Wang LW, Apte SS, McGovern K, Alman BA, Wunder JS. Hedgehog pathway inhibition in chondrosarcoma using the smoothened inhibitor IPI-926 directly inhibits sarcoma cell growth. Molecular Cancer Therapeutics. 13: 1259-69. PMID 24634412 DOI: 10.1158/1535-7163.Mct-13-0731  0.438
2014 Baht GS, Silkstone D, Nadesan P, Whetstone H, Alman BA. Activation of hedgehog signaling during fracture repair enhances osteoblastic-dependent matrix formation. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 32: 581-6. PMID 24347536 DOI: 10.1002/Jor.22562  0.33
2014 Lo WW, Wunder JS, Dickson BC, Campbell V, McGovern K, Alman BA, Andrulis IL. Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma. Cancer. 120: 537-47. PMID 24151134 DOI: 10.1002/Cncr.28439  0.356
2014 Al-Jazrawe M, Poon R, Liu J, Alman B. Abstract 4349: Regulation of proliferation and platelet-derived growth factor expression in desmoid tumors by microRNA-29 Cancer Research. 74: 4349-4349. DOI: 10.1158/1538-7445.Am2014-4349  0.37
2014 Ali S, Whetstone H, Alman B. Hedgehog signaling regulates cholesterol homeostasis in osteoarthritis Osteoarthritis and Cartilage. 22: S160. DOI: 10.1016/J.Joca.2014.02.299  0.323
2013 Ghanbari-Azarnier R, Sato S, Wei Q, Al-Jazrawe M, Alman BA. Targeting stem cell behavior in desmoid tumors (aggressive fibromatosis) by inhibiting hedgehog signaling. Neoplasia (New York, N.Y.). 15: 712-9. PMID 23814483 DOI: 10.1593/Neo.13452  0.431
2013 Craft AM, Ahmed N, Rockel JS, Baht GS, Alman BA, Kandel RA, Grigoriadis AE, Keller GM. Specification of chondrocytes and cartilage tissues from embryonic stem cells. Development (Cambridge, England). 140: 2597-610. PMID 23715552 DOI: 10.1242/Dev.087890  0.333
2013 Stinson JN, Jibb LA, Nguyen C, Nathan PC, Maloney AM, Dupuis LL, Gerstle JT, Alman B, Hopyan S, Strahlendorf C, Portwine C, Johnston DL, Orr M. Development and testing of a multidimensional iPhone pain assessment application for adolescents with cancer. Journal of Medical Internet Research. 15: e51. PMID 23475457 DOI: 10.2196/jmir.2350  0.547
2013 Ho L, Ali SA, Al-Jazrawe M, Kandel R, Wunder JS, Alman BA. Primary cilia attenuate hedgehog signalling in neoplastic chondrocytes. Oncogene. 32: 5388-96. PMID 23246966 DOI: 10.1038/Onc.2012.588  0.754
2013 Ghadakzadeh S, Nik SA, Baht G, Whetstone H, Alman B. Wnt/[beta]-catenin: a candidate pathway for bone repair in neurofibromatosis type-1 Bone Abstracts. DOI: 10.1530/Boneabs.2.Oc25  0.304
2012 Hsu SH, Zhang X, Cheng S, Wunder JS, Hui CC, Alman BA. Suppressor of fused (Sufu) mediates the effect of parathyroid hormone-like hormone (Pthlh) on chondrocyte differentiation in the growth plate. The Journal of Biological Chemistry. 287: 36222-8. PMID 22930757 DOI: 10.1074/Jbc.M112.382275  0.388
2012 Maezawa Y, Binnie M, Li C, Thorner P, Hui CC, Alman B, Taketo MM, Quaggin SE. A New Cre Driver Mouse Line, Tcf21/Pod1-Cre, Targets Metanephric Mesenchyme Plos One. 7. PMID 22792366 DOI: 10.1371/Journal.Pone.0040547  0.312
2012 Poon R, Hong H, Wei X, Pan J, Alman BA. A high throughput screen identifies Nefopam as targeting cell proliferation in β-catenin driven neoplastic and reactive fibroproliferative disorders. Plos One. 7: e37940. PMID 22666417 DOI: 10.1371/Journal.Pone.0037940  0.359
2012 Sparrow DB, Chapman G, Smith AJ, Mattar MZ, Major JA, O'Reilly VC, Saga Y, Zackai EH, Dormans JP, Alman BA, McGregor L, Kageyama R, Kusumi K, Dunwoodie SL. A mechanism for gene-environment interaction in the etiology of congenital scoliosis. Cell. 149: 295-306. PMID 22484060 DOI: 10.1016/J.Cell.2012.02.054  0.322
2012 Wang CY, Wei Q, Han I, Sato S, Ghanbari-Azarnier R, Whetstone H, Poon R, Hu J, Zheng F, Zhang P, Wang W, Wunder JS, Alman BA. Hedgehog and Notch signaling regulate self-renewal of undifferentiated pleomorphic sarcomas. Cancer Research. 72: 1013-22. PMID 22232736 DOI: 10.1158/0008-5472.Can-11-2531  0.37
2012 Zhukova N, Martin D, Lipman T, Castelo-Branco P, Zhang CH, Fraser M, Baskin B, Ray P, Bouffet E, Bristow R, Alman BA, Taylor MD, Malkin D, Hawkins C, Tabori U. Abstract LB-210: Abrogation of mutant TP53 radiation resistance by lithium induced CTNNB1 (β-catenin) activation in medulloblastoma. Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-210  0.304
2012 Jibb L, Stinson J, Nathan P, Maloney A, Dupuis L, Gerstle T, Alman B, Hopyan S, Strahlendorf C, Yanofsky R, Portwine C, Johnston D. Pain Squad: usability testing of a multidimensional electronic pain diary for adolescents with cancer The Journal of Pain. 13: S23. DOI: 10.1016/J.Jpain.2012.01.099  0.573
2011 Atesok KI, Alman BA, Schemitsch EH, Peyser A, Mankin H. Osteoid osteoma and osteoblastoma The Journal of the American Academy of Orthopaedic Surgeons. 19: 678-689. PMID 22052644 DOI: 10.5435/00124635-201111000-00004  0.335
2011 Hsu SH, Zhang X, Yu C, Li ZJ, Wunder JS, Hui CC, Alman BA. Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu. Development (Cambridge, England). 138: 3791-801. PMID 21795282 DOI: 10.1242/Dev.069492  0.382
2011 Amini-Nik S, Glancy D, Boimer C, Whetstone H, Keller C, Alman BA. Pax7 expressing cells contribute to dermal wound repair, regulating scar size through a β-catenin mediated process. Stem Cells (Dayton, Ohio). 29: 1371-9. PMID 21739529 DOI: 10.1002/Stem.688  0.331
2011 Alman BA, Kelley SP, Nam D. Heal thyself: using endogenous regeneration to repair bone. Tissue Engineering. Part B, Reviews. 17: 431-6. PMID 21682602 DOI: 10.1089/Ten.Teb.2011.0189  0.307
2011 Bielefeld KA, Amini-Nik S, Whetstone H, Poon R, Youn A, Wang J, Alman BA. Fibronectin and beta-catenin act in a regulatory loop in dermal fibroblasts to modulate cutaneous healing. The Journal of Biological Chemistry. 286: 27687-97. PMID 21652705 DOI: 10.1074/Jbc.M111.261677  0.328
2011 Rockel JS, Alman BA. Don't hedge your bets: hedgehog signaling as a central mediator of endochondral bone development and cartilage diseases. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 29: 810-5. PMID 21308758 DOI: 10.1002/Jor.21372  0.425
2011 Campbell VT, Nadesan PP, Wang Y, Whetstone H, McGovern K, Read M, Alman BA, Wunder JS. Abstract LB-380: Direct targeting of the Hedgehog pathway in primary chondrosarcoma xenografts with the Smoothened inhibitor IPI-926 Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-380  0.419
2011 Wei Q, Wang CYY, Zheng F, Zhang P, Wang W, Wunder JS, Alman BA. Abstract 479: Targeting tumor initiating cells inhibits tumor growth and serial transplantation ability in soft-tissue sarcomas Cancer Research. 71: 479-479. DOI: 10.1158/1538-7445.Am2011-479  0.423
2010 Wu C, Amini-Nik S, Nik-Amini S, Nadesan P, Stanford WL, Alman BA. Aggressive fibromatosis (desmoid tumor) is derived from mesenchymal progenitor cells. Cancer Research. 70: 7690-8. PMID 20841474 DOI: 10.1158/0008-5472.Can-10-1656  0.398
2010 Szauter KM, Ordas A, Laxer RM, Pope E, Wherrett D, Alman B, Mink M, Boyd CD, Csiszar K, Hinek A. A novel fibrotic disorder associated with increased dermal fibroblast proliferation and downregulation of genes of the microfibrillar network. The British Journal of Dermatology. 163: 1102-15. PMID 20560960 DOI: 10.1111/J.1365-2133.2010.09911.X  0.308
2010 Bovée JV, Hogendoorn PC, Wunder JS, Alman BA. Cartilage tumours and bone development: molecular pathology and possible therapeutic targets. Nature Reviews. Cancer. 10: 481-8. PMID 20535132 DOI: 10.1038/Nrc2869  0.347
2010 Ho L, Alman B. Protecting the hedgerow: p53 and hedgehog pathway interactions. Cell Cycle (Georgetown, Tex.). 9: 506-11. PMID 20081367 DOI: 10.4161/Cc.9.3.10552  0.722
2010 Lin AC, Seeto BL, Bartoszko JM, Khoury MA, Whetstone H, Ho L, Hsu C, Ali AS, Alman BA. Erratum: Corrigendum: Modulating hedgehog signaling can attenuate the severity of osteoarthritis Nature Medicine. 16: 129-129. DOI: 10.1038/Nm0110-129B  0.68
2010 Alman B. Hedgehog signaling in cartilage pathology: a role in osteoarthritis and chondrosarcoma Bone. 46: S9. DOI: 10.1016/J.Bone.2010.01.005  0.326
2009 Lin AC, Seeto BL, Bartoszko JM, Khoury MA, Whetstone H, Ho L, Hsu C, Ali SA, Ali AS, Alman BA. Modulating hedgehog signaling can attenuate the severity of osteoarthritis. Nature Medicine. 15: 1421-5. PMID 19915594 DOI: 10.1038/Nm.2055  0.749
2009 Ho L, Stojanovski A, Whetstone H, Wei QX, Mau E, Wunder JS, Alman B. Gli2 and p53 cooperate to regulate IGFBP-3- mediated chondrocyte apoptosis in the progression from benign to malignant cartilage tumors. Cancer Cell. 16: 126-36. PMID 19647223 DOI: 10.1016/J.Ccr.2009.05.013  0.739
2009 Alman BA. Multiple hereditary exostosis and hedgehog signaling: implications for novel therapies. The Journal of Bone and Joint Surgery. American Volume. 91: 63-7. PMID 19571070 DOI: 10.2106/Jbjs.I.00301  0.375
2009 Poon R, Li C, Alman BA. Beta-catenin mediates soft tissue contracture in clubfoot. Clinical Orthopaedics and Related Research. 467: 1180-5. PMID 19169765 DOI: 10.1007/S11999-008-0692-7  0.308
2009 Chen Y, Alman BA. Wnt pathway, an essential role in bone regeneration. Journal of Cellular Biochemistry. 106: 353-62. PMID 19127541 DOI: 10.1002/Jcb.22020  0.352
2009 Gurung A, Uddin F, Hill RP, Ferguson PC, Alman BA. β-catenin is a mediator of the response of fibroblasts to irradiation American Journal of Pathology. 174: 248-255. PMID 19036807 DOI: 10.2353/Ajpath.2009.080576  0.313
2009 Lavoie JF, Biernaskie JA, Chen Y, Bagli D, Alman B, Kaplan DR, Miller FD. Skin-derived precursors differentiate into skeletogenic cell types and contribute to bone repair. Stem Cells and Development. 18: 893-906. PMID 18834279 DOI: 10.1089/Scd.2008.0260  0.326
2009 Hsu C, Hui C, Alman B. 13-P112 Regulators of Hedgehog signaling in chondrocytes: Sufu and primary cilia Mechanisms of Development. 126. DOI: 10.1016/J.Mod.2009.06.585  0.324
2009 Yan T, Angelini M, Alman BA, Andrulis IL, Wunder JS. Erratum to: PATCHED-ONE or SMOOTHENED Gene Mutations Are Infrequent in Chondrosarcoma Clinical Orthopaedics and Related Research®. 467: 3356-3356. DOI: 10.1007/S11999-009-1134-X  0.326
2008 Alman BA, Wunder JS. Parathyroid hormone-related protein regulates glioma-associated oncogene transcriptional activation: lessons learned from bone development and cartilage neoplasia. Annals of the New York Academy of Sciences. 1144: 36-41. PMID 19076361 DOI: 10.1196/Annals.1418.006  0.366
2008 Gevorgyan A, Sukhu B, Alman BA, Bristow RG, Pang CY, Forrest CR. Radiation effects and radioprotection in MC3T3-E1 mouse calvarial osteoblastic cells. Plastic and Reconstructive Surgery. 122: 1025-35. PMID 18827633 DOI: 10.1097/Prs.0B013E3181845931  0.314
2008 Silkstone D, Hong H, Alman BA. Beta-catenin in the race to fracture repair: in it to Wnt. Nature Clinical Practice. Rheumatology. 4: 413-9. PMID 18560386 DOI: 10.1038/Ncprheum0838  0.354
2008 Yan T, Angelini M, Alman BA, Andrulis IL, Wunder JS. Patched-one or smoothened gene mutations are infrequent in chondrosarcoma. Clinical Orthopaedics and Related Research. 466: 2184-9. PMID 18543049 DOI: 10.1007/S11999-008-0332-2  0.326
2008 Wu C, Alman BA. Side population cells in human cancers. Cancer Letters. 268: 1-9. PMID 18487012 DOI: 10.1016/J.Canlet.2008.03.048  0.322
2007 Alman BA. Skeletal dysplasias and the growth plate. Clinical Genetics. 73: 24-30. PMID 18070126 DOI: 10.1111/J.1399-0004.2007.00933.X  0.316
2007 Wu C, Wei Q, Utomo V, Nadesan P, Whetstone H, Kandel R, Wunder JS, Alman BA. Side population cells isolated from mesenchymal neoplasms have tumor initiating potential. Cancer Research. 67: 8216-22. PMID 17804735 DOI: 10.1158/0008-5472.Can-07-0999  0.343
2007 Chen Y, Whetstone HC, Lin AC, Nadesan P, Wei Q, Poon R, Alman BA. Beta-catenin signaling plays a disparate role in different phases of fracture repair: implications for therapy to improve bone healing. Plos Medicine. 4: e249. PMID 17676991 DOI: 10.1371/Journal.Pmed.0040249  0.36
2007 Tjandra SS, Hsu C, Goh YI, Goh I, Gurung A, Poon R, Nadesan P, Alman BA. IFN-{beta} signaling positively regulates tumorigenesis in aggressive fibromatosis, potentially by modulating mesenchymal progenitors. Cancer Research. 67: 7124-31. PMID 17671179 DOI: 10.1158/0008-5472.Can-07-0686  0.419
2007 Wunder JS, Nielsen TO, Maki RG, O'Sullivan B, Alman BA. Opportunities for improving the therapeutic ratio for patients with sarcoma. The Lancet. Oncology. 8: 513-24. PMID 17540303 DOI: 10.1016/S1470-2045(07)70169-9  0.316
2007 Baliko F, Bright T, Poon R, Cohen B, Egan SE, Alman BA. Inhibition of notch signaling induces neural differentiation in Ewing sarcoma. The American Journal of Pathology. 170: 1686-94. PMID 17456774 DOI: 10.2353/Ajpath.2007.060971  0.421
2007 Li CF, MacDonald JR, Wei RY, Ray J, Lau K, Kandel C, Koffman R, Bell S, Scherer SW, Alman BA. Human sterile alpha motif domain 9, a novel gene identified as down-regulated in aggressive fibromatosis, is absent in the mouse. Bmc Genomics. 8: 92. PMID 17407603 DOI: 10.1186/1471-2164-8-92  0.305
2007 Alman BA, Horton WA. Developmental biology in orthopaedics. Summary of the 2006 AAOS research symposium. The Journal of Bone and Joint Surgery. American Volume. 89: 668-71. PMID 17332117 DOI: 10.2106/Jbjs.F.01609  0.334
2007 Mau E, Whetstone H, Yu C, Hopyan S, Wunder JS, Alman BA. PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms. Developmental Biology. 305: 28-39. PMID 17328886 DOI: 10.1016/J.Ydbio.2007.01.031  0.662
2007 Li CF, Wei RY, Baliko F, Bapat B, Alman BA. An association between the 4G polymorphism in the PAI-1 promoter and the development of aggressive fibromatosis (desmoid tumor) in familial adenomatous polyposis patients. Familial Cancer. 6: 89-95. PMID 17160433 DOI: 10.1007/S10689-006-9109-5  0.319
2007 Chen Y, Whetstone HC, Youn A, Nadesan P, Chow EC, Lin AC, Alman BA. Beta-catenin signaling pathway is crucial for bone morphogenetic protein 2 to induce new bone formation. The Journal of Biological Chemistry. 282: 526-33. PMID 17085452 DOI: 10.1074/Jbc.M602700200  0.359
2006 Cheon SS, Wei Q, Gurung A, Youn A, Bright T, Poon R, Whetstone H, Guha A, Alman BA. Beta-catenin regulates wound size and mediates the effect of TGF-beta in cutaneous healing. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 692-701. PMID 16581977 DOI: 10.1096/Fj.05-4759Com  0.309
2006 Tiet TD, Hopyan S, Nadesan P, Gokgoz N, Poon R, Lin AC, Yan T, Andrulis IL, Alman BA, Wunder JS. Constitutive hedgehog signaling in chondrosarcoma up-regulates tumor cell proliferation. The American Journal of Pathology. 168: 321-30. PMID 16400033 DOI: 10.2353/Ajpath.2006.050001  0.692
2005 Hopyan S, Nadesan P, Yu C, Wunder J, Alman BA. Dysregulation of hedgehog signalling predisposes to synovial chondromatosis. The Journal of Pathology. 206: 143-50. PMID 15834844 DOI: 10.1002/Path.1761  0.677
2005 Fen Li C, Kandel C, Baliko F, Nadesan P, Brünner N, Alman BA. Plasminogen activator inhibitor-1 (PAI-1) modifies the formation of aggressive fibromatosis (desmoid tumor). Oncogene. 24: 1615-24. PMID 15674349 DOI: 10.1038/Sj.Onc.1208193  0.388
2004 Khurana JS, Ogino S, Shen T, Parekh H, Scherbel U, Delong W, Feldman MD, Zhang PJ, Wolfe HJ, Alman BA. Bone Morphogenetic Proteins Are Expressed by Both Bone-Forming and Non-Bone-Forming Lesions. Archives of Pathology & Laboratory Medicine. 128: 1267-1269. PMID 15506826 DOI: 10.1043/1543-2165(2004)128<1267:Bmpaeb>2.0.Co;2  0.319
2004 Kong Y, Poon R, Nadesan P, Di Muccio T, Fodde R, Khokha R, Alman BA. Matrix metalloproteinase activity modulates tumor size, cell motility, and cell invasiveness in murine aggressive fibromatosis. Cancer Research. 64: 5795-803. PMID 15313922 DOI: 10.1158/0008-5472.Can-03-3112  0.379
2004 Denys H, Jadidizadeh A, Amini Nik S, Van Dam K, Aerts S, Alman BA, Cassiman JJ, Tejpar S. Identification of IGFBP-6 as a significantly downregulated gene by beta-catenin in desmoid tumors. Oncogene. 23: 654-64. PMID 14737101 DOI: 10.1038/Sj.Onc.1207160  0.38
2003 Yu C, Le AT, Yeger H, Perbal B, Alman BA. NOV (CCN3) regulation in the growth plate and CCN family member expression in cartilage neoplasia. The Journal of Pathology. 201: 609-15. PMID 14648665 DOI: 10.1002/Path.1468  0.328
2003 Tolg C, Poon R, Fodde R, Turley EA, Alman BA. Genetic deletion of receptor for hyaluronan-mediated motility (Rhamm) attenuates the formation of aggressive fibromatosis (desmoid tumor). Oncogene. 22: 6873-82. PMID 14534534 DOI: 10.1038/Sj.Onc.1206811  0.414
2003 Tiet TD, Alman BA. Developmental pathways in musculoskeletal neoplasia: involvement of the Indian Hedgehog-parathyroid hormone-related protein pathway. Pediatric Research. 53: 539-43. PMID 12612211 DOI: 10.1203/01.Pdr.0000054688.93486.18  0.41
2002 Cheon SS, Cheah AY, Turley S, Nadesan P, Poon R, Clevers H, Alman BA. beta-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds. Proceedings of the National Academy of Sciences of the United States of America. 99: 6973-8. PMID 11983872 DOI: 10.1073/Pnas.102657399  0.343
2002 Hopyan S, Gokgoz N, Poon R, Gensure RC, Yu C, Cole WG, Bell RS, Jüppner H, Andrulis IL, Wunder JS, Alman BA. A mutant PTH/PTHrP type I receptor in enchondromatosis. Nature Genetics. 30: 306-10. PMID 11850620 DOI: 10.1038/Ng844  0.671
2001 Meng X, Poon R, Zhang X, Cheah A, Ding Q, Hui CC, Alman B. Suppressor of fused negatively regulates beta-catenin signaling. The Journal of Biological Chemistry. 276: 40113-9. PMID 11477086 DOI: 10.1074/Jbc.M105317200  0.372
2001 Poon R, Smits R, Li C, Jagmohan-Changur S, Kong M, Cheon S, Yu C, Fodde R, Alman BA. Cyclooxygenase-two (COX-2) modulates proliferation in aggressive fibromatosis (desmoid tumor). Oncogene. 20: 451-60. PMID 11313976 DOI: 10.1038/Sj.Onc.1204107  0.378
2001 Li C, Nguyen Q, Cole WG, Alman BA. Potential Treatment for Clubfeet Based on Growth Factor Blockade Journal of Pediatric Orthopaedics. 21: 372-377. DOI: 10.1097/01241398-200105000-00021  0.324
2000 Couture J, Mitri A, Lagace R, Smits R, Berk T, Bouchard HL, Fodde R, Alman B, Bapat B. A germline mutation at the extreme 3' end of the APC gene results in a severe desmoid phenotype and is associated with overexpression of beta-catenin in the desmoid tumor. Clinical Genetics. 57: 205-12. PMID 10782927 DOI: 10.1034/J.1399-0004.2000.570306.X  0.36
1999 Tejpar S, Nollet F, Li C, Wunder JS, Michils G, dal Cin P, Van Cutsem E, Bapat B, van Roy F, Cassiman JJ, Alman BA. Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor). Oncogene. 18: 6615-20. PMID 10597266 DOI: 10.1038/Sj.Onc.1203041  0.308
1999 Hopyan S, Gokgoz N, Bell RS, Andrulis IL, Alman BA, Wunder JS. Expression of osteocalcin and its transcriptional regulators core-binding factor alpha 1 and MSX2 in osteoid-forming tumours. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 17: 633-8. PMID 10569470 DOI: 10.2106/00004623-200002000-00034  0.627
1998 Li C, Bapat B, Alman BA. Adenomatous polyposis coli gene mutation alters proliferation through its beta-catenin-regulatory function in aggressive fibromatosis (desmoid tumor). The American Journal of Pathology. 153: 709-14. PMID 9736021 DOI: 10.1016/S0002-9440(10)65614-3  0.335
1997 Alman BA, Pajerski ME, Diaz-Cano S, Corboy K, Wolfe HJ. Aggressive fibromatosis (desmoid tumor) is a monoclonal disorder. Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B. 6: 98-101. PMID 9098648 DOI: 10.1097/00019606-199704000-00005  0.344
1997 Muller E, Castagnaro M, Yandel DW, Wolfe HJ, Alman BA. Molecular genetic and immunohistochemical analysis of the tumor suppressor genes Rb and p53 in palmar and aggressive fibromatosis. Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B. 5: 194-200. PMID 8866233 DOI: 10.1097/00019606-199609000-00008  0.307
1995 Alman BA, Naber SP, Terek RM, Jiranek WA, Goldberg MJ, Wolfe HJ. Platelet-derived growth factor in fibrous musculoskeletal disorders: a study of pathologic tissue sections and in vitro primary cell cultures. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 13: 67-77. PMID 7853106 DOI: 10.1002/Jor.1100130111  0.309
1995 Terek RM, Jiranek WA, Goldberg MJ, Wolfe HJ, Alman BA. The expression of platelet-derived growth-factor gene in Dupuytren contracture. The Journal of Bone and Joint Surgery. American Volume. 77: 1-9. PMID 7822340 DOI: 10.2106/00004623-199501000-00001  0.313
1991 Alman BA, Goldberg MJ. Solitary osteochondroma of the clavicle. Journal of Pediatric Orthopedics. 11: 181-3. PMID 2010516 DOI: 10.1097/01241398-199103000-00007  0.341
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