Bharati Bapat - Publications

Affiliations: 
Laboratory Medicine and Pathobiology University of Toronto, Toronto, ON, Canada 
Area:
Oncology, Genetics, Molecular Biology

137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Peter MR, Bilenky M, Shi Y, Pu J, Kamdar S, Hansen AR, Fleshner NE, Sridhar SS, Joshua AM, Hirst M, Xu W, Bapat B. A novel methylated cell-free DNA marker panel to monitor treatment response in metastatic prostate cancer. Epigenomics. 14: 811-822. PMID 35818933 DOI: 10.2217/epi-2022-0103  0.447
2022 Jeyapala R, Kamdar S, Olkhov-Mitsel E, Zlotta A, Fleshner N, Visakorpi T, van der Kwast T, Bapat B. Combining CAPRA-S With Tumor IDC/C Features Improves the Prognostication of Biochemical Recurrence in Prostate Cancer Patients. Clinical Genitourinary Cancer. PMID 35151601 DOI: 10.1016/j.clgc.2022.01.003  0.337
2021 Peter MR, Bilenky M, Davies A, Isserlin R, Bader GD, Fleshner NE, Hirst M, Zoubeidi A, Bapat B. Distinct DNA methylation patterns associated with treatment resistance in metastatic castration resistant prostate cancer. Scientific Reports. 11: 6630. PMID 33758253 DOI: 10.1038/s41598-021-85812-3  0.426
2020 Kamdar S, Fleshner NE, Bapat B. A 38-gene model comprised of key TET2-associated genes shows additive utility to high-risk prostate cancer cases in the prognostication of biochemical recurrence. Bmc Cancer. 20: 953. PMID 33008340 DOI: 10.1186/s12885-020-07438-4  0.316
2020 Peter MR, Bilenky M, Isserlin R, Bader GD, Shen SY, De Carvalho DD, Hansen AR, Hu P, Fleshner NE, Joshua AM, Hirst M, Bapat B. Dynamics of the cell-free DNA methylome of metastatic prostate cancer during androgen-targeting treatment. Epigenomics. PMID 32867540 DOI: 10.2217/Epi-2020-0173  0.523
2020 Hoey C, Jeyapala R, Boutros PC, Bapat B, Liu SK. Urinary biomarkers in prostate cancer: to the miRnome and beyond. Translational Andrology and Urology. 9: 843-845. PMID 32420197 DOI: 10.21037/Tau.2019.11.25  0.426
2020 Connell SP, O'Reilly E, Tuzova A, Webb M, Hurst R, Mills R, Zhao F, Bapat B, Cooper CS, Perry AS, Clark J, Brewer DS. Development of a multivariable risk model integrating urinary cell DNA methylation and cell-free RNA data for the detection of significant prostate cancer. The Prostate. PMID 32153047 DOI: 10.1002/pros.23968  0.377
2020 Hermanns T, Savio AJ, Olkhov-Mitsel E, Mari A, Wettstein MS, Saba K, Bhindi B, Kuk C, Poyet C, Wild PJ, Noon A, Bashir S, Juvet T, Rendon RA, Waltregny D, ... ... Bapat B, et al. A noninvasive urine-based methylation biomarker panel to detect bladder cancer and discriminate cancer grade. Urologic Oncology. PMID 32081560 DOI: 10.1016/J.Urolonc.2020.01.007  0.456
2019 Savio AJ, Kamdar S, Jeyapala R, Olkhov-Mitsel E, Cuizon C, Finelli A, Zlotta AR, Toi A, Fleshner NE, van der Kwast T, Bapat B. Methylation markers in prostate biopsies are prognosticators for late biochemical recurrence and therapy after surgery in prostate cancer patients. The Journal of Molecular Diagnostics : Jmd. PMID 31605802 DOI: 10.1016/J.Jmoldx.2019.08.003  0.504
2019 Jeyapala R, Kamdar S, Olkhov-Mitsel E, Savio AJ, Zhao F, Cuizon C, Liu RS, Zlotta A, Fleshner N, van der Kwast T, Bapat B. An integrative DNA methylation model for improved prognostication of postsurgery recurrence and therapy in prostate cancer patients. Urologic Oncology. PMID 31558364 DOI: 10.1016/J.Urolonc.2019.08.017  0.44
2019 Jeyapala R, Savio AJ, Olkhov-Mitsel E, Kamdar S, Zhao F, Cuizon C, Liu RSC, Zlotta A, Fleshner N, van der Kwast T, Bapat B. GBX2 Methylation Is a Novel Prognostic Biomarker and Improves Prediction of Biochemical Recurrence Among Patients with Prostate Cancer Negative for Intraductal Carcinoma and Cribriform Architecture. European Urology Oncology. 2: 231-238. PMID 31200836 DOI: 10.1016/J.Euo.2018.08.003  0.464
2019 Jeon J, Olkhov-Mitsel E, Xie H, Yao CQ, Zhao F, Jahangiri S, Cuizon C, Scarcello S, Jeyapala R, Watson JD, Fraser M, Ray J, Commisso K, Loblaw A, Fleshner NE, ... ... Bapat B, et al. Temporal stability and prognostic biomarker potential of the prostate cancer urine transcriptome. Journal of the National Cancer Institute. PMID 31161221 DOI: 10.1093/Jnci/Djz112  0.391
2019 Kamdar S, Isserlin R, Van der Kwast T, Zlotta AR, Bader GD, Fleshner NE, Bapat B. Exploring targets of TET2-mediated methylation reprogramming as potential discriminators of prostate cancer progression. Clinical Epigenetics. 11: 54. PMID 30917865 DOI: 10.1186/S13148-019-0651-Z  0.552
2019 O'Reilly E, Tuzova AV, Walsh AL, Russell NM, O'Brien O, Kelly S, Dhomhnallain ON, DeBarra L, Dale CM, Brugman R, Clarke G, Schmidt O, O'Meachair S, Patil D, Pellegrini KL, ... ... Bapat B, et al. epiCaPture: A Urine DNA Methylation Test for Early Detection of Aggressive Prostate Cancer. Jco Precision Oncology. 2019. PMID 30801051 DOI: 10.1200/PO.18.00134  0.424
2019 Zhao F, Vesprini D, Liu RSC, Olkhov-Mitsel E, Klotz LH, Loblaw A, Liu SK, Bapat B. Combining urinary DNA methylation and cell-free microRNA biomarkers for improved monitoring of prostate cancer patients on active surveillance. Urologic Oncology. PMID 30777394 DOI: 10.1016/J.Urolonc.2019.01.031  0.495
2019 Goldberg H, Cheung DC, Chandrasekar T, Klaassen Z, Wallis CJD, Kulkarni GS, Sayyid R, Evans A, Masoomian M, Bapat B, Van Der Kwast T, Hamilton RJ, Zlotta A, Fleshner N. Are there differences between de novo and secondary upper tract urothelial carcinoma tumours? Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada. PMID 30763230 DOI: 10.5489/Cuaj.5595  0.384
2019 Hermanns* T, Savio AJ, Olkhov-Mitsel E, Mari A, Saba K, Bhindi B, Gill B, Sykes J, Kuk C, Poyet C, Wild PJ, Noon A, Bashir S, Juvet T, Rendon RA, ... ... Bapat B, et al. PD18-07 A NON-INVASIVE URINE-BASED METHYLATION BIOMARKER PANEL FOR BLADDER CANCER DETECTION Journal of Urology. 201. DOI: 10.1097/01.Ju.0000555579.23708.62  0.479
2018 Zhao F, Olkhov-Mitsel E, Kamdar S, Jeyapala R, Garcia J, Hurst R, Hanna MY, Mills R, Tuzova AV, O'Reilly E, Kelly S, Cooper C, Brewer D, Perry AS, ... ... Bapat B, et al. A urine-based DNA methylation assay, ProCUrE, to identify clinically significant prostate cancer. Clinical Epigenetics. 10: 147. PMID 30470249 DOI: 10.1186/S13148-018-0575-Z  0.511
2018 Bapat B. Re: Urinary DNA Methylation Biomarkers for Noninvasive Prediction of Aggressive Disease in Patients with Prostate Cancer on Active Surveillance: F. Zhao, E. Olkhov-Mitsel, T. van der Kwast, J. Sykes, D. Zdravic, V. Venkateswaran, A. R. Zlotta, A. Loblaw, N. E. Fleshner, L. Klotz, D. Vesprini and B. Bapat J Urol 2017;197:335-341. The Journal of Urology. PMID 29428633 DOI: 10.1016/J.Juro.2017.10.061  0.394
2017 Liu RSC, Olkhov-Mitsel E, Jeyapala R, Zhao F, Commisso K, Klotz L, Loblaw A, Liu SK, Vesprini D, Fleshner NE, Bapat B. Assessment of serum microRNA biomarkers for predicting reclassification of prostate cancer patients on active surveillance. The Journal of Urology. PMID 29246734 DOI: 10.1016/J.Juro.2017.12.006  0.41
2017 Olkhov-Mitsel E, Siadat F, Kron K, Liu L, Savio AJ, Trachtenberg J, Fleshner N, van der Kwast T, Bapat B. Distinct DNA methylation alterations are associated with cribriform architecture and intraductal carcinoma in Gleason pattern 4 prostate tumors. Oncology Letters. 14: 390-396. PMID 28693181 DOI: 10.3892/Ol.2017.6140  0.768
2017 Briollais L, Ozcelik H, Xu J, Kwiatkowski M, Lalonde E, Sendorek DH, Fleshner NE, Recker F, Kuk C, Olkhov-Mitsel E, Juvet T, Prassas I, Trachtenberg J, Toi A, Fraser M, ... ... Bapat B, et al. Germline Mutations in the Kallikrein 6 Region and Predisposition for Aggressive Prostate Cancer. Journal of the National Cancer Institute. 109. PMID 28376164 DOI: 10.1093/Jnci/Djw258  0.475
2017 Savio AJ, Bapat B. Modulation of transcription factor binding and epigenetic regulation of the MLH1 CpG island and shore by polymorphism rs1800734 in colorectal cancer. Epigenetics. 0. PMID 28304185 DOI: 10.1080/15592294.2017.1305527  0.35
2017 Olkhov-Mitsel E, Savio AJ, Kron KJ, Pethe VV, Hermanns T, Fleshner NE, van Rhijn BW, van der Kwast TH, Zlotta AR, Bapat B. Epigenome-Wide DNA Methylation Profiling Identifies Differential Methylation Biomarkers in High-Grade Bladder Cancer. Translational Oncology. 10: 168-177. PMID 28167242 DOI: 10.1016/J.Tranon.2017.01.001  0.767
2016 Zhao F, Olkhov-Mitsel E, van der Kwast T, Sykes J, Zdravic D, Venkateswaran V, Zlotta AR, Loblaw A, Fleshner NE, Klotz L, Vesprini D, Bapat B. Urinary DNA methylation biomarkers for non-invasive prediction of aggressive disease in prostate cancer patients on Active Surveillance. The Journal of Urology. PMID 27545574 DOI: 10.1016/J.Juro.2016.08.081  0.469
2016 White-Al Habeeb NM, Garcia J, Fleshner N, Bapat B. Metformin elicits antitumor effects and downregulates the histone methyltransferase multiple myeloma SET domain (MMSET) in prostate cancer cells. The Prostate. PMID 27404348 DOI: 10.1002/Pros.23235  0.467
2016 Pouessel D, Neuzillet Y, Mertens LS, van der Heijden MS, de Jong J, Sanders J, Peters D, Leroy K, Manceau A, Maille P, Soyeux P, Moktefi A, Semprez F, Vordos D, de la Taille A, ... ... Bapat B, et al. Tumor Heterogeneity of Fibroblast Growth Factor Receptor 3 (FGFR3) Mutations in Invasive Bladder Cancer: Implications for Peri-Operative anti-FGFR3 Treatment. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. PMID 27091807 DOI: 10.1093/Annonc/Mdw170  0.376
2016 Kamdar SN, Ho LT, Kron KJ, Isserlin R, van der Kwast T, Zlotta AR, Fleshner NE, Bader G, Bapat B. Dynamic interplay between locus-specific DNA methylation and hydroxymethylation regulates distinct biological pathways in prostate carcinogenesis. Clinical Epigenetics. 8: 32. PMID 26981160 DOI: 10.1186/S13148-016-0195-4  0.777
2016 Savio AJ, Daftary D, Dicks E, Buchanan DD, Parfrey PS, Young JP, Weisenberger D, Green RC, Gallinger S, McLaughlin JR, Knight JA, Bapat B. Promoter methylation of ITF2, but not APC, is associated with microsatellite instability in two populations of colorectal cancer patients. Bmc Cancer. 16: 113. PMID 26884349 DOI: 10.1186/S12885-016-2149-9  0.483
2015 Weisenberger DJ, Levine AJ, Long TI, Buchanan DD, Walters R, Clendenning M, Rosty C, Joshi AD, Stern MC, Le Marchand L, Lindor NM, Daftary D, Gallinger S, Selander T, Bapat B, et al. Association of the colorectal CpG island methylator phenotype with molecular features, risk factors, and family history. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 24: 512-9. PMID 25587051 DOI: 10.1158/1055-9965.Epi-14-1161  0.452
2015 van Rhijn BW, Musquera M, Liu L, Vis AN, Zuiverloon TC, van Leenders GJ, Kirkels WJ, Zwarthoff EC, Boevé ER, Jöbsis AC, Bapat B, Jewett MA, Zlotta AR, van der Kwast TH. Molecular and clinical support for a four-tiered grading system for bladder cancer based on the WHO 1973 and 2004 classifications. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 28: 695-705. PMID 25431236 DOI: 10.1038/Modpathol.2014.154  0.314
2015 Savio AJ, Bapat B. Beyond the island: epigenetic biomarkers of colorectal and prostate cancer. Methods in Molecular Biology (Clifton, N.J.). 1238: 103-24. PMID 25421657 DOI: 10.1007/978-1-4939-1804-1_6  0.539
2015 Kamdar SN, Ho LT, Isserlin R, Kron KJ, Kwast Tvd, Zlotta AR, Fleshner NE, Bader G, Bapat B. Abstract B1-32: Genome-wide integrative analysis correlating locus-specific DNA methylation and hydroxymethylation to gene expression in normal prostate cells Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-B1-32  0.51
2015 Savio AJ, Lemire M, Mrkonjic M, Gallinger S, Zanke BW, Hudson TJ, Bapat B. Abstract 1058: Novel insights into the genetic and epigenetic regulation of the MLH1 CpG island and shore in colorectal cancer Cancer Research. 75: 1058-1058. DOI: 10.1158/1538-7445.Am2015-1058  0.483
2015 Hermanns T, Olkhov-Mitsel E, Savio A, Gill B, Sykes J, Bhindi B, Juvet T, Kuk C, Noon A, Rendon R, Waltregny D, Van Der Kwast T, Finelli A, Fleshner N, Lo K, ... Bapat B, et al. 755 A five-gene DNA-methylation biomarker panel sensitively detects bladder cancer and discriminates between high-grade and low-grade disease in voided urine European Urology Supplements. 14: e755. DOI: 10.1016/S1569-9056(15)60746-1  0.393
2015 Zhao F, Vesprini D, Olkhov-Mitsel E, Zdravic D, Zlotta A, Venkateswaran V, Loblaw A, Van Der Kwast T, Fleshner N, Klotz L, Bapat B. PD46-07 URINARY DNA METHYLATION BIOMARKERS: A NON-INVASIVE METHOD FOR PROSTATE CANCER MONITORING Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.2738  0.51
2015 Olkhov-Mitsel E, Siadat F, Trudel D, Kron K, Liu l, Fleshner NE, Van der Kwast T, Bapat B. MP6-14 DNA METHYLATION ABERRATIONS IN GLEASON PATTERN 4 PROSTATIC CARCINOMA WITH CRIBRIFORM ARCHITECTURE OR INTRADUCTAL CARCINOMA: A RADICAL PROSTATECTOMY STUDY Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.261  0.732
2015 Savio A, Olkhov-Mitsel E, Kron K, Hermanns T, van Rhijn B, Zlotta A, van der Kwast T, Bapat B. MP68-06 TISSUE-BASED DNA METHYLATION PROFILING ESTABLISHES A NOVEL PANEL OF BIOMARKERS FOR DISCRIMINATION OF HIGH-GRADE VERSUS LOW-GRADE BLADDER CANCER Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.2468  0.763
2015 Hermanns T, Olkhov-Mitsel E, Savio A, Gill B, Sykes J, Bhindi B, Juvet T, Kuk C, Noon A, Rendon R, Waltregny D, van der Kwast TH, Finelli A, Fleshner NE, Lo K, ... Bapat B, et al. MP68-04 A FIVE—GENE DNA—METHYLATION BIOMARKER PANEL SENSITIVELY DETECTS BLADDER CANCER AND DISCRIMINATES BETWEEN HIGH—GRADE AND LOW—GRADE DISEASE IN VOIDED URINE Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.2466  0.34
2015 Briollais L, Ozcelik H, Kwiatkowski M, Xu J, Savas S, Olkhov-Mitsel E, Recker F, Kuk C, Hanna S, Fleshner NE, Juvet T, Friedlander M, Li H, Chadwick K, Trachtenberg J, ... ... Bapat B, et al. Mp61-01 Functional Role Of The Kallikrein 6 Region Of The Kallikrein Locus In Genetic Predisposition For Aggressive (Gleason ≥8) Prostate Cancer: Fine-Mapping And Methylation Study In A Canadian Cohort And The Swiss Arm Of The European Randomized Study For Prostate Cancer Screening The Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.2182  0.435
2014 White-Al Habeeb NM, Ho LT, Olkhov-Mitsel E, Kron K, Pethe V, Lehman M, Jovanovic L, Fleshner N, van der Kwast T, Nelson CC, Bapat B. Integrated analysis of epigenomic and genomic changes by DNA methylation dependent mechanisms provides potential novel biomarkers for prostate cancer. Oncotarget. 5: 7858-69. PMID 25277202 DOI: 10.18632/Oncotarget.2313  0.785
2014 Neuzillet Y, van Rhijn BW, Prigoda NL, Bapat B, Liu L, Bostrom PJ, Fleshner NE, Gallie BL, Zlotta AR, Jewett MA, van der Kwast TH. FGFR3 mutations, but not FGFR3 expression and FGFR3 copy-number variations, are associated with favourable non-muscle invasive bladder cancer. Virchows Archiv : An International Journal of Pathology. 465: 207-13. PMID 24880661 DOI: 10.1007/S00428-014-1596-4  0.343
2014 Olkhov-Mitsel E, Zdravic D, Kron K, van der Kwast T, Fleshner N, Bapat B. Novel multiplex MethyLight protocol for detection of DNA methylation in patient tissues and bodily fluids. Scientific Reports. 4: 4432. PMID 24651255 DOI: 10.1038/Srep04432  0.763
2014 Saraon P, Trudel D, Kron K, Dmitromanolakis A, Trachtenberg J, Bapat B, van der Kwast T, Jarvi KA, Diamandis EP. Evaluation and prognostic significance of ACAT1 as a marker of prostate cancer progression. The Prostate. 74: 372-80. PMID 24311408 DOI: 10.1002/Pros.22758  0.757
2014 Briollais L, Xu J, Kwiatkowski M, Friedlander M, Recker F, Kuk C, Hanna S, Fleshner N, Bapat B, Juvet T, Li H, Chadwick K, Trachtenberg J, Nesbitt M, Van Der Kwast T, et al. 206 Fine-mapping of the Kallikrein region and its role in prostate cancer aggressiveness: Results from a Canadian cohort and the European Randomized Study for Prostate Cancer Screening European Urology Supplements. 13: e206. DOI: 10.1016/S1569-9056(14)60203-7  0.344
2014 NEUZILLET Y, MERTENS L, SHARIAT S, BOSTROM P, MIRTTI T, SAGALOWSKY A, ASHFAQ R, BROEKS A, VAN M, HEIJDEN D, PETERS D, CURIAL C, JONG JD, HORENBLAS S, HURST C, ... ... BAPAT B, et al. MP28-20 PATHOLOGICAL VALIDATION OF ADJUVANT ANTI - FIBROBLAST GROWTH FACTOR RECEPTOR 3 (FGFR3) FOR PERSONALIZED TREATMENT OF BLADDER CANCER Journal of Urology. 191. DOI: 10.1016/J.Juro.2014.02.669  0.307
2014 Mertens L, Zuiverloon T, Neuzillet Y, Shariat S, Abas C, Bostrom P, Vermeij M, Mirtti T, Sagalowsky A, Boormans J, Peters D, Ashfaq R, de Jong J, Broeks A, Fleshner N, ... ... Bapat B, et al. MP28-12 MOLECULAR MARKERS (FGFR3 MUTATION; P53 & KI-67 EXPRESSION) AND CLINICAL OUTCOME OF RADICAL CYSTECTOMY FOR BLADDER CANCER: A MULTICENTER, MULTILAB STUDY Journal of Urology. 191. DOI: 10.1016/J.Juro.2014.02.661  0.379
2014 Briollais L, Xu J, Kwiatkowski M, Friedlander M, Recker F, Kuk C, Hanna S, Fleshner NE, Bapat B, Juvet T, Li H, van der Kwast TH, Diamandis EP, Zlotta AR, Ozcelik H. MP49-20 FINE-MAPPING OF THE KALLIKREIN REGION AND ITS ROLE IN PROSTATE CANCER AGGRESSIVENESS: RESULTS FROM A CANADIAN COHORT AND THE EUROPEAN RANDOMIZED STUDY FOR PROSTATE CANCER SCREENING Journal of Urology. 191. DOI: 10.1016/J.Juro.2014.02.1121  0.45
2013 Kron K, Trudel D, Pethe V, Briollais L, Fleshner N, van der Kwast T, Bapat B. Altered DNA methylation landscapes of polycomb-repressed loci are associated with prostate cancer progression and ERG oncogene expression in prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3450-61. PMID 23549870 DOI: 10.1158/1078-0432.Ccr-12-3139  0.783
2013 Skeldon SC, Semotiuk K, Aronson M, Holter S, Gallinger S, Pollett A, Kuk C, van Rhijn B, Bostrom P, Cohen Z, Fleshner NE, Jewett MA, Hanna S, Shariat SF, Van Der Kwast TH, ... ... Bapat B, et al. Patients with Lynch syndrome mismatch repair gene mutations are at higher risk for not only upper tract urothelial cancer but also bladder cancer. European Urology. 63: 379-85. PMID 22883484 DOI: 10.1016/J.Eururo.2012.07.047  0.438
2013 Samplaski M, Zhu Y, Hou H, Savio A, Bapat B, Bader G, McKerlie C, Jarvi K, Lo K. 2035 EPIGENETIC REGULATION OF GENE EXPRESSION PATTERNS IN HUMAN TESTIS XENOTRANSPLANTS AFTER TREATMENT WITH CYCLOPHOSPHAMIDE Journal of Urology. 189. DOI: 10.1016/J.Juro.2013.02.2454  0.32
2012 Olkhov-Mitsel E, Bapat B. Strategies for discovery and validation of methylated and hydroxymethylated DNA biomarkers. Cancer Medicine. 1: 237-60. PMID 23342273 DOI: 10.1002/Cam4.22  0.438
2012 Savio AJ, Lemire M, Mrkonjic M, Gallinger S, Zanke BW, Hudson TJ, Bapat B. MLH1 region polymorphisms show a significant association with CpG island shore methylation in a large cohort of healthy individuals. Plos One. 7: e51531. PMID 23240038 DOI: 10.1371/Journal.Pone.0051531  0.411
2012 Rawson JB, Sun Z, Dicks E, Daftary D, Parfrey PS, Green RC, Gallinger S, McLaughlin JR, Wang PP, Knight JA, Bapat B. Vitamin D intake is negatively associated with promoter methylation of the Wnt antagonist gene DKK1 in a large group of colorectal cancer patients. Nutrition and Cancer. 64: 919-28. PMID 22966878 DOI: 10.1080/01635581.2012.711418  0.418
2012 Olkhov-Mitsel E, Van der Kwast T, Kron KJ, Ozcelik H, Briollais L, Massey C, Recker F, Kwiatkowski M, Fleshner NE, Diamandis EP, Zlotta AR, Bapat B. Quantitative DNA methylation analysis of genes coding for kallikrein-related peptidases 6 and 10 as biomarkers for prostate cancer. Epigenetics : Official Journal of the Dna Methylation Society. 7: 1037-45. PMID 22874102 DOI: 10.4161/epi.21524  0.767
2012 Plummer JM, Chin SN, Aronson M, Graham RP, Williams NP, Bapat B, Wharfe G, Pollett A, Gallinger S. Lynch syndrome in a predominantly Afrocentric population: a clinicopathological and genetic study. Canadian Journal of Surgery. Journal Canadien De Chirurgie. 55: 294-300. PMID 22854115 DOI: 10.1503/Cjs.037410  0.356
2012 Rawson JB, Bapat B. Epigenetic biomarkers in colorectal cancer diagnostics. Expert Review of Molecular Diagnostics. 12: 499-509. PMID 22702366 DOI: 10.1586/Erm.12.39  0.44
2012 Kron K, Liu L, Trudel D, Pethe V, Trachtenberg J, Fleshner N, Bapat B, van der Kwast T. Correlation of ERG expression and DNA methylation biomarkers with adverse clinicopathologic features of prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 2896-904. PMID 22452941 DOI: 10.1158/1078-0432.Ccr-11-2901  0.787
2012 van Rhijn BW, Liu L, Vis AN, Bostrom PJ, Zuiverloon TC, Fleshner NE, van der Aa MN, Alkhateeb SS, Bangma CH, Jewett MA, Zwarthoff EC, Bapat B, van der Kwast TH, Zlotta AR. Prognostic value of molecular markers, sub-stage and European Organisation for the Research and Treatment of Cancer risk scores in primary T1 bladder cancer. Bju International. 110: 1169-76. PMID 22448597 DOI: 10.1111/J.1464-410X.2012.10996.X  0.345
2012 Win AK, Young JP, Lindor NM, Tucker KM, Ahnen DJ, Young GP, Buchanan DD, Clendenning M, Giles GG, Winship I, Macrae FA, Goldblatt J, Southey MC, Arnold J, Thibodeau SN, ... ... Bapat B, et al. Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 958-64. PMID 22331944 DOI: 10.1200/Jco.2011.39.5590  0.399
2012 van Rhijn BW, van der Kwast TH, Liu L, Fleshner NE, Bostrom PJ, Vis AN, Alkhateeb SS, Bangma CH, Jewett MA, Zwarthoff EC, Zlotta AR, Bapat B. The FGFR3 mutation is related to favorable pT1 bladder cancer. The Journal of Urology. 187: 310-4. PMID 22099989 DOI: 10.1016/J.Juro.2011.09.008  0.413
2012 Ryan P, Mulligan AM, Aronson M, Ferguson SE, Bapat B, Semotiuk K, Holter S, Kwon J, Kalloger SE, Gilks CB, Gallinger S, Pollett A, Clarke BA. Comparison of clinical schemas and morphologic features in predicting Lynch syndrome in mutation-positive patients with endometrial cancer encountered in the context of familial gastrointestinal cancer registries Cancer. 118: 681-688. PMID 21721000 DOI: 10.1002/Cncr.26323  0.372
2012 Stakhovskyi O, Margel D, van der Kwast T, van Rhijn BW, Bostrom PJ, Thoms J, Bristow RG, Fleshner NE, Jewett MA, Bapat B, Zlotta AR. 551 HEAT SHOCK PROTEIN 70 (HSP70) AS A RECURRENCE MARKER FOR PT1 BLADDER CANCER Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.626  0.304
2012 van Rhijn BW, Stakhovskyi O, Margel D, van der Kwast T, Bostrom PJ, Thoms J, Bristow RG, Milosevic M, Fleshner NE, Jewett MA, Bapat B, Kim W, Zlotta AR. 1075 HEAT SHOCK PROTEIN 70 (HSP70) AND FGFR3 IN NON MUSCLE INVASIVE BLADDER CANCER TREATED WITH BCG GENE EXPRESSION AND PROTEIN EXPRESSION ANALYSIS USING 2 DIFFERENT VALIDATION COHORTS Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.1181  0.327
2011 Rawson JB, Mrkonjic M, Daftary D, Dicks E, Buchanan DD, Younghusband HB, Parfrey PS, Young JP, Pollett A, Green RC, Gallinger S, McLaughlin JR, Knight JA, Bapat B. Promoter methylation of Wnt5a is associated with microsatellite instability and BRAF V600E mutation in two large populations of colorectal cancer patients. British Journal of Cancer. 104: 1906-12. PMID 21587258 DOI: 10.1038/Bjc.2011.165  0.463
2011 Cicek MS, Lindor NM, Gallinger S, Bapat B, Hopper JL, Jenkins MA, Young J, Buchanan D, Walsh MD, Le Marchand L, Burnett T, Newcomb PA, Grady WM, Haile RW, Casey G, et al. Quality assessment and correlation of microsatellite instability and immunohistochemical markers among population- and clinic-based colorectal tumors results from the Colon Cancer Family Registry. The Journal of Molecular Diagnostics : Jmd. 13: 271-81. PMID 21497289 DOI: 10.1016/J.Jmoldx.2010.12.004  0.388
2011 Kohonen-Corish MR, Macrae F, Genuardi M, Aretz S, Bapat B, Bernstein IT, Burn J, Cotton RG, den Dunnen JT, Frebourg T, Greenblatt MS, Hofstra R, Holinski-Feder E, Lappalainen I, Lindblom A, et al. Deciphering the colon cancer genes--report of the InSiGHT-Human Variome Project Workshop, UNESCO, Paris 2010. Human Mutation. 32: 491-4. PMID 21387463 DOI: 10.1002/Humu.21450  0.41
2011 Rawson JB, Manno M, Mrkonjic M, Daftary D, Dicks E, Buchanan DD, Younghusband HB, Parfrey PS, Young JP, Pollett A, Green RC, Gallinger S, McLaughlin JR, Knight JA, Bapat B. Promoter methylation of Wnt antagonists DKK1 and SFRP1 is associated with opposing tumor subtypes in two large populations of colorectal cancer patients. Carcinogenesis. 32: 741-7. PMID 21304055 DOI: 10.1093/Carcin/Bgr020  0.453
2011 Liu L, Kron KJ, Pethe VV, Demetrashvili N, Nesbitt ME, Trachtenberg J, Ozcelik H, Fleshner NE, Briollais L, van der Kwast TH, Bapat B. Association of tissue promoter methylation levels of APC, TGFβ2, HOXD3 and RASSF1A with prostate cancer progression. International Journal of Cancer. Journal International Du Cancer. 129: 2454-62. PMID 21207416 DOI: 10.1002/Ijc.25908  0.768
2011 Perera S, Mrkonjic M, Rawson JB, Bapat B. Functional effects of the MLH1-93G>A polymorphism on MLH1/EPM2AIP1 promoter activity. Oncology Reports. 25: 809-15. PMID 21206982 DOI: 10.3892/Or.2010.1129  0.354
2011 Skeldon S, Aronson M, Semotiuk K, Pollett A, Van RB, Bostrom P, Gallinger S, Cohen Z, Fleshner N, Jewett M, Hanna S, Kuk C, Van DKT, Evans A, Bapat B, et al. 172 INVESTIGATING THE RISK OF BLADDER CANCER AMONG HEREDITARY NON-POLYPOSIS COLORECTAL CANCER (HNPCC) PATIENTS WITH CONFIRMED MISMATCH REPAIR (MMR) GENE MUTATIONS European Urology Supplements. 10: 78. DOI: 10.1016/S1569-9056(11)60174-7  0.347
2011 Skeldon SC, Aronson M, Semotiuk K, Pollett A, van Rhijn BW, Bostrom PJ, Gallinger S, Cohen Z, Fleshner NE, Jewett MA, Hanna S, Kuk C, van der Kwast TH, Evans A, Bapat B, et al. 1244 INVESTIGATING BLADDER CANCER RISK IN HEREDITARY NON-POLYPOSIS COLORECTAL CANCER PATIENTS WITH MISMATCH REPAIR GENE MUTATIONS Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.915  0.451
2011 van Rhijn BW, Bostrom PJ, Shariat SF, Finelli A, Sagalowsky AI, Fleshner NE, Bapat B, Kortekangas H, Ashfaq R, Mirtti T, Jewett MA, Lotan Y, van der Kwast TH, Zlotta AR. 1401 THE FGFR3 MUTATION IDENTIFIES PATIENTS WITH FAVORABLE DISEASE AT RADICAL CYSTECTOMY FOR BLADDER CANCER Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.1292  0.413
2010 Demetrashvili N, Kron K, Pethe V, Bapat B, Briollais L. How to Deal with Batch Effect in Sequential Microarray Experiments? Molecular Informatics. 29: 387-93. PMID 27463194 DOI: 10.1002/Minf.200900019  0.641
2010 Mrkonjic M, Roslin NM, Greenwood CM, Raptis S, Pollett A, Laird PW, Pethe VV, Chiang T, Daftary D, Dicks E, Thibodeau SN, Gallinger S, Parfrey PS, Younghusband HB, Potter JD, ... ... Bapat B, et al. Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer. Plos One. 5: e13314. PMID 20967208 DOI: 10.1371/Journal.Pone.0013314  0.478
2010 Perera S, Li B, Tsitsikotas S, Ramyar L, Pollett A, Semotiuk K, Bapat B. A novel and rapid method of determining the effect of unclassified MLH1 genetic variants on differential allelic expression. The Journal of Molecular Diagnostics : Jmd. 12: 757-64. PMID 20864636 DOI: 10.2353/Jmoldx.2010.090240  0.338
2010 Woods MO, Younghusband HB, Parfrey PS, Gallinger S, McLaughlin J, Dicks E, Stuckless S, Pollett A, Bapat B, Mrkonjic M, de la Chapelle A, Clendenning M, Thibodeau SN, Simms M, Dohey A, et al. The genetic basis of colorectal cancer in a population-based incident cohort with a high rate of familial disease. Gut. 59: 1369-77. PMID 20682701 DOI: 10.1136/Gut.2010.208462  0.402
2010 Diamandis EP, Sidransky D, Laird PW, Cairns P, Bapat B. Epigenomics-based diagnostics. Clinical Chemistry. 56: 1216-9. PMID 20472819 DOI: 10.1373/Clinchem.2010.148007  0.384
2010 Walsh MD, Buchanan DD, Cummings MC, Pearson SA, Arnold ST, Clendenning M, Walters R, McKeone DM, Spurdle AB, Hopper JL, Jenkins MA, Phillips KD, Suthers GK, George J, Goldblatt J, ... ... Bapat B, et al. Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the colon cancer family registry. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 2214-24. PMID 20215533 DOI: 10.1158/1078-0432.Ccr-09-3058  0.353
2010 Kron KJ, Liu L, Pethe VV, Demetrashvili N, Nesbitt ME, Trachtenberg J, Ozcelik H, Fleshner NE, Briollais L, van der Kwast TH, Bapat B. DNA methylation of HOXD3 as a marker of prostate cancer progression. Laboratory Investigation; a Journal of Technical Methods and Pathology. 90: 1060-7. PMID 20212450 DOI: 10.1038/Labinvest.2010.57  0.776
2010 Perera S, Ramyar L, Mitri A, Pollett A, Gallinger S, Speevak MD, Aronson M, Bapat B. A novel complex mutation in MSH2 contributes to both Muir-Torre and Lynch Syndrome. Journal of Human Genetics. 55: 37-41. PMID 19911012 DOI: 10.1038/Jhg.2009.119  0.362
2010 Lindor NM, Rabe KG, Petersen GM, Chen H, Bapat B, Hopper J, Young J, Jenkins M, Potter J, Newcomb P, Templeton A, Lemarchand L, Grove J, Burgio MR, Haile R, et al. Parent of origin effects on age at colorectal cancer diagnosis. International Journal of Cancer. Journal International Du Cancer. 127: 361-6. PMID 19904757 DOI: 10.1002/Ijc.25037  0.389
2010 Lindor NM, Yang P, Evans I, Schowalter K, De Andrade M, Li J, Jeavons E, Peterson G, Gallinger S, Bapat B, Hopper J, Jass J, Jenkins M, Templeton A, Potter J, et al. Alpha-1-antitrypsin deficiency and smoking as risk factors for mismatch repair deficient colorectal cancer: a study from the colon cancer family registry. Molecular Genetics and Metabolism. 99: 157-9. PMID 19853488 DOI: 10.1016/J.Ymgme.2009.09.010  0.378
2010 Aronson M, Gallinger S, Rothenmund H, Semotiuk K, Holter S, Berk T, Pollett A, Cohen Z, Bapat B, Kim H, Gryfe R. Clinicopathologic and genetic features of young patients with colorectal cancer Hereditary Cancer in Clinical Practice. 8: P2. DOI: 10.1186/1897-4287-8-S1-P2  0.332
2010 Bapat B, Rawson JB, Mrkonjic M, Green RC, Gallinger S, Younghusband B, McLaughlin J, Knight JA. Abstract B28: Epigenetic contribution of Wnt antagonists SFRP1 and DKK1 as prognostic markers in colorectal cancer Clinical Cancer Research. 16. DOI: 10.1158/1078-0432.Tcme10-B28  0.466
2010 van Rhijn B, Bapat B, Liu L, Bostrom P, Fleshner N, Jewett M, Zlotta A, van der Kwast T. 1147 FGFR3 PROTEIN OVER-EXPRESSION IN THE ABSENCE OF A FGFR3 MUTATION IS NOT ASSOCIATED WITH FAVOURABLE DISEASE CHARACTERISTICS IN BLADDER CANCER Journal of Urology. 183. DOI: 10.1016/J.Juro.2010.02.646  0.398
2009 Choi YH, Cotterchio M, McKeown-Eyssen G, Neerav M, Bapat B, Boyd K, Gallinger S, McLaughlin J, Aronson M, Briollais L. Penetrance of colorectal cancer among MLH1/MSH2 carriers participating in the colorectal cancer familial registry in Ontario. Hereditary Cancer in Clinical Practice. 7: 14. PMID 19698169 DOI: 10.1186/1897-4287-7-14  0.445
2009 van der Kwast TH, Bapat B. Predicting favourable prognosis of urothelial carcinoma: gene expression and genome profiling. Current Opinion in Urology. 19: 516-21. PMID 19553819 DOI: 10.1097/Mou.0B013E32832Eb45F  0.367
2009 Chong G, Jarry J, Marcus V, Thiffault I, Winocour S, Monczak Y, Drouin R, Latreille J, Australie K, Bapat B, Gordon PH, Giguère Y, Gologan A, Galiatsatos P, Jass JR, et al. High frequency of exon deletions and putative founder effects in French Canadian Lynch syndrome families. Human Mutation. 30: E797-812. PMID 19459153 DOI: 10.1002/Humu.21056  0.3
2009 Kron K, Pethe V, Briollais L, Sadikovic B, Ozcelik H, Sunderji A, Venkateswaran V, Pinthus J, Fleshner N, van der Kwast T, Bapat B. Discovery of novel hypermethylated genes in prostate cancer using genomic CpG island microarrays. Plos One. 4: e4830. PMID 19283074 DOI: 10.1371/Journal.Pone.0004830  0.78
2009 Bapat B, Lindor NM, Baron J, Siegmund K, Li L, Zheng Y, Haile R, Gallinger S, Jass JR, Young JP, Cotterchio M, Jenkins M, Grove J, Casey G, Thibodeau SN, et al. The association of tumor microsatellite instability phenotype with family history of colorectal cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 967-75. PMID 19258475 DOI: 10.1158/1055-9965.Epi-08-0878  0.404
2008 Poynter JN, Siegmund KD, Weisenberger DJ, Long TI, Thibodeau SN, Lindor N, Young J, Jenkins MA, Hopper JL, Baron JA, Buchanan D, Casey G, Levine AJ, Le Marchand L, Gallinger S, ... Bapat B, et al. Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 3208-15. PMID 18990764 DOI: 10.1158/1055-9965.Epi-08-0512  0.414
2008 Charames GS, Ramyar L, Mitri A, Berk T, Cheng H, Jung J, Bocangel P, Chodirker B, Greenberg C, Spriggs E, Bapat B. A large novel deletion in the APC promoter region causes gene silencing and leads to classical familial adenomatous polyposis in a Manitoba Mennonite kindred. Human Genetics. 124: 535-41. PMID 18982352 DOI: 10.1007/S00439-008-0579-4  0.349
2008 Pabalan N, Bapat B, Sung L, Jarjanazi H, Francisco-Pabalan O, Ozcelik H. Cyclin D1 Pro241Pro (CCND1-G870A) polymorphism is associated with increased cancer risk in human populations: a meta-analysis. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 2773-81. PMID 18843022 DOI: 10.1158/1055-9965.Epi-08-0169  0.377
2008 Pethe VV, Bapat B. Molecular Genetic Etiology of Prostate Cancer The Open Genomics Journal. 1: 13-21. DOI: 10.2174/1875693X00801010013  0.506
2007 Mrkonjic M, Raptis S, Green RC, Monga N, Daftary D, Dicks E, Younghusband HB, Parfrey PS, Gallinger SS, McLaughlin JR, Knight JA, Bapat B. MSH2 118T>C and MSH6 159C>T promoter polymorphisms and the risk of colorectal cancer. Carcinogenesis. 28: 2575-80. PMID 17942459 DOI: 10.1093/Carcin/Bgm229  0.359
2007 Raptis S, Mrkonjic M, Green RC, Pethe VV, Monga N, Chan YM, Daftary D, Dicks E, Younghusband BH, Parfrey PS, Gallinger SS, McLaughlin JR, Knight JA, Bapat B. MLH1 -93G>A promoter polymorphism and the risk of microsatellite-unstable colorectal cancer. Journal of the National Cancer Institute. 99: 463-74. PMID 17374836 DOI: 10.1093/Jnci/Djk095  0.394
2007 Esufali S, Charames GS, Pethe VV, Buongiorno P, Bapat B. Activation of tumor-specific splice variant Rac1b by dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells. Cancer Research. 67: 2469-79. PMID 17363564 DOI: 10.1158/0008-5472.Can-06-2843  0.38
2007 Croitoru ME, Cleary SP, Berk T, Di Nicola N, Kopolovic I, Bapat B, Gallinger S. Germline MYH mutations in a clinic-based series of Canadian multiple colorectal adenoma patients. Journal of Surgical Oncology. 95: 499-506. PMID 17219385 DOI: 10.1002/Jso.20724  0.353
2007 Shin EJ, Chappell E, Pethe V, Hersey K, van der Kwast T, Fleshner N, Bapat B. MYH mutations are rare in prostate cancer. Journal of Cancer Research and Clinical Oncology. 133: 373-8. PMID 17219200 DOI: 10.1007/S00432-006-0181-X  0.484
2007 Li CF, Wei RY, Baliko F, Bapat B, Alman BA. An association between the 4G polymorphism in the PAI-1 promoter and the development of aggressive fibromatosis (desmoid tumor) in familial adenomatous polyposis patients. Familial Cancer. 6: 89-95. PMID 17160433 DOI: 10.1007/S10689-006-9109-5  0.321
2007 Raptis S, Mrkonjic M, Green RC, Daftary D, Pethe V, Dicks E, Younghusband BH, Parfrey PS, Gallinger SS, McLaughlin JR, Knight JA, Bapat B. Response: Re: MLH1 −93G>A Promoter Polymorphism and the Risk of Microsatellite-Unstable Colorectal Cancer Journal of the National Cancer Institute. 99: 1490-1491. DOI: 10.1093/Jnci/Djm140  0.374
2006 Charames GS, Bapat B. Cyclooxygenase-2 knockdown by RNA interference in colon cancer. International Journal of Oncology. 28: 543-9. PMID 16391811 DOI: 10.3892/Ijo.28.2.543  0.392
2005 Woods MO, Hyde AJ, Curtis FK, Stuckless S, Green JS, Pollett AF, Robb JD, Green RC, Croitoru ME, Careen A, Chaulk JA, Jegathesan J, McLaughlin JR, Gallinger SS, Younghusband HB, ... Bapat BV, et al. High frequency of hereditary colorectal cancer in Newfoundland likely involves novel susceptibility genes. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 6853-61. PMID 16203774 DOI: 10.1158/1078-0432.Ccr-05-0726  0.344
2005 Lindor NM, Rabe K, Petersen GM, Haile R, Casey G, Baron J, Gallinger S, Bapat B, Aronson M, Hopper J, Jass J, LeMarchand L, Grove J, Potter J, Newcomb P, et al. Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type X. Jama. 293: 1979-85. PMID 15855431 DOI: 10.1001/Jama.293.16.1979  0.425
2005 Durno C, Aronson M, Bapat B, Cohen Z, Gallinger S. Family history and molecular features of children, adolescents, and young adults with colorectal carcinoma. Gut. 54: 1146-50. PMID 15845562 DOI: 10.1136/Gut.2005.066092  0.324
2005 Casey G, Lindor NM, Papadopoulos N, Thibodeau SN, Moskow J, Steelman S, Buzin CH, Sommer SS, Collins CE, Butz M, Aronson M, Gallinger S, Barker MA, Young JP, Jass JR, ... ... Bapat B, et al. Conversion analysis for mutation detection in MLH1 and MSH2 in patients with colorectal cancer. Jama. 293: 799-809. PMID 15713769 DOI: 10.1001/Jama.293.7.799  0.388
2005 Chetty R, Salahshor S, Bapat B, Berk T, Croitoru M, Gallinger S. Intraductal papillary mucinous neoplasm of the pancreas in a patient with attenuated familial adenomatous polyposis. Journal of Clinical Pathology. 58: 97-101. PMID 15623495 DOI: 10.1136/Jcp.2004.020925  0.322
2004 Vassileva V, Millar A, Briollais L, Chapman W, Bapat B. Apoptotic and growth regulatory genes as mutational targets in mismatch repair deficient endometrioid adenocarcinomas of young patients. Oncology Reports. 11: 931-7. PMID 15010897 DOI: 10.3892/Or.11.4.931  0.376
2003 Charames GS, Bapat B. Genomic instability and cancer. Current Molecular Medicine. 3: 589-96. PMID 14601634 DOI: 10.2174/1566524033479456  0.436
2003 Truta B, Allen BA, Conrad PG, Kim YS, Berk T, Gallinger S, Bapat B, Terdiman JP, Sleisenger MH. Genotype and phenotype of patients with both familial adenomatous polyposis and thyroid carcinoma. Familial Cancer. 2: 95-9. PMID 14574158 DOI: 10.1023/A:1025762706854  0.378
2003 Brezden-Masley C, Aronson MD, Bapat B, Pollett A, Gryfe R, Redston M, Gallinger S. Hereditary nonpolyposis colorectal cancer--molecular basis. Surgery. 134: 29-33. PMID 12874579 DOI: 10.1067/Msy.2003.176  0.393
2002 Charames GS, Cheng H, Gilpin CA, Hunter AG, Berk T, Bapat B. A novel aberrant splice site mutation in the APC gene. Journal of Medical Genetics. 39: 754-7. PMID 12362034 DOI: 10.1136/Jmg.39.10.754  0.366
2002 Vassileva V, Millar A, Briollais L, Chapman W, Bapat B. Genes involved in DNA repair are mutational targets in endometrial cancers with microsatellite instability. Cancer Research. 62: 4095-9. PMID 12124347  0.303
2002 Zysman M, Saka A, Millar A, Knight J, Chapman W, Bapat B. Methylation of adenomatous polyposis coli in endometrial cancer occurs more frequently in tumors with microsatellite instability phenotype. Cancer Research. 62: 3663-6. PMID 12097272  0.378
2002 Hutter P, Wijnen J, Rey-Berthod C, Thiffault I, Verkuijlen P, Farber D, Hamel N, Bapat B, Thibodeau SN, Burn J, Wu J, MacNamara E, Heinimann K, Chong G, Foulkes WD. An MLH1 haplotype is over-represented on chromosomes carrying an HNPCC predisposing mutation in MLH1. Journal of Medical Genetics. 39: 323-7. PMID 12011148 DOI: 10.1136/Jmg.39.5.323  0.302
2002 Zysman MA, Chapman WB, Bapat B. Considerations when analyzing the methylation status of PTEN tumor suppressor gene. The American Journal of Pathology. 160: 795-800. PMID 11891178 DOI: 10.1016/S0002-9440(10)64902-4  0.471
2001 Esplen MJ, Madlensky L, Butler K, McKinnon W, Bapat B, Wong J, Aronson M, Gallinger S. Motivations and psychosocial impact of genetic testing for HNPCC American Journal of Medical Genetics. 103: 9-15. PMID 11562928 DOI: 10.1002/Ajmg.1493  0.325
2000 Charames GS, Millar AL, Pal T, Narod S, Bapat B. Do MSH6 mutations contribute to double primary cancers of the colorectum and endometrium? Human Genetics. 107: 623-9. PMID 11153917 DOI: 10.1007/S004390000417  0.404
2000 Ferda Percin E, Ploder LA, Yu JJ, Arici K, Horsford DJ, Rutherford A, Bapat B, Cox DW, Duncan AM, Kalnins VI, Kocak-Altintas A, Sowden JC, Traboulsi E, Sarfarazi M, McInnes RR. Human microphthalmia associated with mutations in the retinal homeobox gene CHX10. Nature Genetics. 25: 397-401. PMID 10932181 DOI: 10.1038/78071  0.323
2000 Couture J, Mitri A, Lagace R, Smits R, Berk T, Bouchard HL, Fodde R, Alman B, Bapat B. A germline mutation at the extreme 3' end of the APC gene results in a severe desmoid phenotype and is associated with overexpression of beta-catenin in the desmoid tumor. Clinical Genetics. 57: 205-12. PMID 10782927 DOI: 10.1034/J.1399-0004.2000.570306.X  0.334
1999 Marcus VA, Madlensky L, Gryfe R, Kim H, So K, Millar A, Temple LKF, Hsieh E, Hiruki T, Narod S, Bapat BV, Gallinger S, Redston M. Immunohistochemistry for hMLH1 and hMSH2: A practical test for DNA mismatch repair-deficient tumors American Journal of Surgical Pathology. 23: 1248-1255. PMID 10524526 DOI: 10.1097/00000478-199910000-00010  0.313
1999 Jiang CY, Esufali S, Berk T, Gallinger S, Cohen Z, Tobi M, Redston M, Bapat B. STK11/LKB1 germline mutations are not identified in most Peutz-Jeghers syndrome patients. Clinical Genetics. 56: 136-41. PMID 10517250 DOI: 10.1034/J.1399-0004.1999.560207.X  0.381
1999 Bapat B, Noorani H, Cohen Z, Berk T, Mitri A, Gallie B, Pritzker K, Gallinger S, Detsky AS. Cost comparison of predictive genetic testing versus conventional clinical screening for familial adenomatous polyposis. Gut. 44: 698-703. PMID 10205208 DOI: 10.1136/Gut.44.5.698  0.362
1999 Millar AL, Pal T, Madlensky L, Sherman C, Temple L, Mitri A, Cheng H, Marcus V, Gallinger S, Redston M, Bapat B, Narod S. Mismatch repair gene defects contribute to the genetic basis of double primary cancers of the colorectum and endometrium Human Molecular Genetics. 8: 823-829. PMID 10196371 DOI: 10.1093/Hmg/8.5.823  0.455
1998 Peralta RC, Casson AG, Wang RN, Keshavjee S, Redston M, Bapat B. Distinct regions of frequent loss of heterozygosity of chromosome 5p and 5q in human esophageal cancer. International Journal of Cancer. 78: 600-5. PMID 9808529 DOI: 10.1002/(Sici)1097-0215(19981123)78:5<600::Aid-Ijc12>3.0.Co;2-1  0.312
1998 Soravia C, Berk T, Madlensky L, Mitri A, Cheng H, Gallinger S, Cohen Z, Bapat B. Genotype-phenotype correlations in attenuated adenomatous Polyposis coli American Journal of Human Genetics. 62: 1290-1301. PMID 9585611 DOI: 10.1086/301883  0.334
1998 Gryfe R, Swallow C, Bapat B, Redston M, Gallinger S, Couture J. Molecular biology of colorectal cancer. Current Problems in Cancer. 21: 233-300. PMID 9438104 DOI: 10.1016/S0147-0272(97)80003-7  0.462
1998 Temple L, Bapat B, Madlensky L, Redston M, Hiruki T, Cohen Z, McLeod R, Gallinger S. Hereditary non-polyposis colorectal cancer (HNPCC): Cancer patterns in germline mutation (hMSH2, hMLH1) positive (M+) and mutation negative (M−) families Gastroenterology. 114: A688. DOI: 10.1016/S0016-5085(98)82823-0  0.394
1997 Madlensky L, Bapat B, Redston M, Pearl R, Gallinger S, Cohen Z. Using genetic information to make surgical decisions: Report of a case of a 13-year-old boy with colon cancer Diseases of the Colon and Rectum. 40: 240-243. PMID 9075764 DOI: 10.1007/Bf02054995  0.434
1996 Eppert K, Scherer SW, Ozcelik H, Pirone R, Hoodless P, Kim H, Tsui LC, Bapat B, Gallinger S, Andrulis IL, Thomsen GH, Wrana JL, Attisano L. MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell. 86: 543-52. PMID 8752209 DOI: 10.1016/S0092-8674(00)80128-2  0.341
1995 Reitmair AH, Schmits R, Ewel A, Bapat B, Redston M, Mitri A, Waterhouse P, Mittrücker HW, Wakeham A, Liu B. MSH2 deficient mice are viable and susceptible to lymphoid tumours. Nature Genetics. 11: 64-70. PMID 7550317 DOI: 10.1038/Ng0995-64  0.347
1995 Xia L, Denis KAS, Bapat B. Evidence for a novel exon in the coding region of the adenomatous polyposis coli (APC) gene Genomics. 28: 589-591. PMID 7490101 DOI: 10.1006/Geno.1995.1195  0.328
1995 Denis K, Mitri A, Berk T, Hiruki T, Gallinger S, Cohen Z, Bapat B. Unequal expression of APC alleles in colorectal adenomas of patients with familial adenomatous polyposis (FAP) Gastroenterology. 108: A540. DOI: 10.1016/0016-5085(95)26473-6  0.305
1995 Bapat B, Xia L, Berk T, Nong Y, Gallinger S. Isolation of differentially expressed messenger RNAs from peri-ampullary cancer associated with familial adenomatous polyposis (FAP) Gastroenterology. 108: A447. DOI: 10.1016/0016-5085(95)26103-6  0.34
1994 Bapat B, Berk T, Mitri A, Cohen Z, Gallinger S, Stern H. Characterization of two novel adenomatous polyposis coli (APC) gene mutations in patients with familial adenomatous polyposis (FAP) Human Mutation. 4: 253-256. PMID 7866403 DOI: 10.1002/Humu.1380040404  0.325
1993 Bapat B, Odze R, Mitri A, Berk T, Ward M, Gallinger S. Identification of somatic APC gene mutations in periampullary adenomas in a patient with familial adenomatous polyposis (FAP) Human Molecular Genetics. 2: 1957-1959. PMID 8281160 DOI: 10.1093/Hmg/2.11.1957  0.324
Show low-probability matches.