| Year |
Citation |
Score |
| 2019 |
Ahmad F, Tomar D, Aryal A C S, Elmoselhi AB, Thomas M, Elrod JW, Tilley DG, Force T. Nicotinamide riboside kinase-2 alleviates ischemia-induced heart failure through P38 signaling. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165609. PMID 31743747 DOI: 10.1016/J.Bbadis.2019.165609 |
0.41 |
|
| 2019 |
Guo Y, Sui JY, Kim K, Zhang Z, Qu XA, Nam YJ, Willette RN, Barnett JV, Knollmann BC, Force T, Lal H. Cardiomyocyte HIPK2 Maintains Basal Cardiac Function via ERK Signaling. Circulation. PMID 31581792 DOI: 10.1161/Circulationaha.119.040740 |
0.406 |
|
| 2019 |
Schroer AK, Bersi MR, Clark CR, Zhang Q, Sanders LH, Hatzopoulos AK, Force TL, Majka SM, Lal H, Merryman WD. Cadherin-11 blockade reduces inflammation-driven fibrotic remodeling and improves outcomes after myocardial infarction. Jci Insight. 4. PMID 31534054 DOI: 10.1172/Jci.Insight.131545 |
0.396 |
|
| 2019 |
Ahmad F, Singh AP, Tomar D, Rahmani M, Zhang Q, Woodgett JR, Tilley DG, Lal H, Force T. Cardiomyocyte-GSK-3α promotes mPTP opening and heart failure in mice with chronic pressure overload. Journal of Molecular and Cellular Cardiology. PMID 30928428 DOI: 10.1016/J.Yjmcc.2019.03.020 |
0.335 |
|
| 2019 |
Singh AP, Glennon MS, Umbarkar P, Gupte M, Galindo CL, Zhang Q, Force T, Becker JR, Lal H. Ponatinib-induced cardiotoxicity: delineating the signaling mechanisms and potential rescue strategies. Cardiovascular Research. PMID 30629146 DOI: 10.1093/Cvr/Cvz006 |
0.31 |
|
| 2018 |
Prakash Singh A, Umbarkar P, Guo Y, Force T, Gupte M, Lal H. Inhibition of GSK-3 to induce cardiomyocyte proliferation-a recipe for in situ cardiac regeneration. Cardiovascular Research. PMID 30321309 DOI: 10.1093/cvr/cvy255 |
0.373 |
|
| 2016 |
Zhou J, Ahmad F, Parikh S, Hoffman NE, Rajan S, Verma VK, Song J, Yuan A, Shanmughapriya S, Guo Y, Gao E, Koch WJ, Woodgett JR, Muniswamy M, Kishore R, ... ... Force T, et al. Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy. Circulation Research. PMID 26976650 DOI: 10.1161/Circresaha.116.308544 |
0.465 |
|
| 2016 |
Jacob F, Yonis AY, Cuello F, Luther P, Schulze T, Eder A, Streichert T, Mannhardt I, Hirt MN, Schaaf S, Stenzig J, Force T, Eschenhagen T, Hansen A. Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue. Plos One. 11: e0145937. PMID 26840448 DOI: 10.1371/Journal.Pone.0145937 |
0.44 |
|
| 2015 |
Lal H, Ahmad F, Woodgett J, Force T. The GSK-3 family as therapeutic target for myocardial diseases. Circulation Research. 116: 138-49. PMID 25552693 DOI: 10.1161/Circresaha.116.303613 |
0.402 |
|
| 2015 |
Cross MJ, Berridge BR, Clements PJ, Cove-Smith L, Force TL, Hoffmann P, Holbrook M, Lyon AR, Mellor HR, Norris AA, Pirmohamed M, Tugwood JD, Sidaway JE, Park BK. Physiological, pharmacological and toxicological considerations of drug-induced structural cardiac injury. British Journal of Pharmacology. 172: 957-74. PMID 25302413 DOI: 10.1111/Bph.12979 |
0.383 |
|
| 2014 |
Ponikowski P, Anker SD, AlHabib KF, Cowie MR, Force TL, Hu S, Jaarsma T, Krum H, Rastogi V, Rohde LE, Samal UC, Shimokawa H, Budi Siswanto B, Sliwa K, Filippatos G. Heart failure: preventing disease and death worldwide. Esc Heart Failure. 1: 4-25. PMID 28834669 DOI: 10.1002/Ehf2.12005 |
0.342 |
|
| 2014 |
Plana JC, Galderisi M, Barac A, Ewer MS, Ky B, Scherrer-Crosbie M, Ganame J, Sebag IA, Agler DA, Badano LP, Banchs J, Cardinale D, Carver J, Cerqueira M, DeCara JM, ... ... Force T, et al. Expert consensus for multimodality imaging evaluation of adult patients during and after cancer therapy: a report from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. European Heart Journal Cardiovascular Imaging. 15: 1063-93. PMID 25239940 DOI: 10.1093/Ehjci/Jeu192 |
0.414 |
|
| 2014 |
Plana JC, Galderisi M, Barac A, Ewer MS, Ky B, Scherrer-Crosbie M, Ganame J, Sebag IA, Agler DA, Badano LP, Banchs J, Cardinale D, Carver J, Cerqueira M, DeCara JM, ... ... Force T, et al. Expert consensus for multimodality imaging evaluation of adult patients during and after cancer therapy: a report from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 27: 911-39. PMID 25172399 DOI: 10.1016/J.Echo.2014.07.012 |
0.393 |
|
| 2014 |
Ahmad F, Lal H, Zhou J, Vagnozzi RJ, Yu JE, Shang X, Woodgett JR, Gao E, Force T. Cardiomyocyte-specific deletion of Gsk3α mitigates post-myocardial infarction remodeling, contractile dysfunction, and heart failure. Journal of the American College of Cardiology. 64: 696-706. PMID 25125302 DOI: 10.1016/J.Jacc.2014.04.068 |
0.693 |
|
| 2014 |
Lal H, Ahmad F, Zhou J, Yu JE, Vagnozzi RJ, Guo Y, Yu D, Tsai EJ, Woodgett J, Gao E, Force T. Cardiac fibroblast glycogen synthase kinase-3β regulates ventricular remodeling and dysfunction in ischemic heart. Circulation. 130: 419-30. PMID 24899689 DOI: 10.1161/Circulationaha.113.008364 |
0.736 |
|
| 2014 |
Lal H, Ahmad F, Parikh S, Force T. Troponin I-Interacting Protein Kinase Circulation. 78: 1514-1519. PMID 24899531 DOI: 10.1253/Circj.Cj-14-0543 |
0.472 |
|
| 2014 |
Duran JM, Makarewich CA, Trappanese D, Gross P, Husain S, Dunn J, Lal H, Sharp TE, Starosta T, Vagnozzi RJ, Berretta RM, Barbe M, Yu D, Gao E, Kubo H, ... Force T, et al. Sorafenib cardiotoxicity increases mortality after myocardial infarction. Circulation Research. 114: 1700-12. PMID 24718482 DOI: 10.1161/Circresaha.114.303200 |
0.719 |
|
| 2014 |
Springer J, Tschirner A, Haghikia A, Von Haehling S, Lal H, Grzesiak A, Kaschina E, Palus S, Pötsch M, Von Websky K, Hocher B, Latouche C, Jaisser F, Morawietz L, Coats AJS, ... ... Force T, et al. Prevention of liver cancer cachexia-induced cardiac wasting and heart failure European Heart Journal. 35: 932-941. PMID 23990596 DOI: 10.1093/Eurheartj/Eht302 |
0.434 |
|
| 2013 |
Hoffman NE, Chandramoorthy HC, Shamugapriya S, Zhang X, Rajan S, Mallilankaraman K, Gandhirajan RK, Vagnozzi RJ, Ferrer LM, Sreekrishnanilayam K, Natarajaseenivasan K, Vallem S, Force T, Choi ET, Cheung JY, et al. MICU1 motifs define mitochondrial calcium uniporter binding and activity. Cell Reports. 5: 1576-88. PMID 24332854 DOI: 10.1016/J.Celrep.2013.11.026 |
0.643 |
|
| 2013 |
Vagnozzi RJ, Gatto GJ, Kallander LS, Hoffman NE, Mallilankaraman K, Ballard VL, Lawhorn BG, Stoy P, Philp J, Graves AP, Naito Y, Lepore JJ, Gao E, Madesh M, Force T. Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart. Science Translational Medicine. 5: 207ra141. PMID 24132636 DOI: 10.1126/Scitranslmed.3006479 |
0.738 |
|
| 2013 |
Ky B, Vejpongsa P, Yeh ET, Force T, Moslehi JJ. Emerging paradigms in cardiomyopathies associated with cancer therapies. Circulation Research. 113: 754-64. PMID 23989717 DOI: 10.1161/Circresaha.113.300218 |
0.391 |
|
| 2013 |
Yu J, Deliu E, Zhang XQ, Hoffman NE, Carter RL, Grisanti LA, Brailoiu GC, Madesh M, Cheung JY, Force T, Abood ME, Koch WJ, Tilley DG, Brailoiu E. Differential activation of cultured neonatal cardiomyocytes by plasmalemmal versus intracellular G protein-coupled receptor 55. The Journal of Biological Chemistry. 288: 22481-92. PMID 23814062 DOI: 10.1074/Jbc.M113.456178 |
0.314 |
|
| 2013 |
Force T, Wang Y. Mechanism-Based Engineering Against Anthracycline Cardiotoxicity Circulation. 128: 98-100. PMID 23757311 DOI: 10.1161/Circulationaha.113.003688 |
0.301 |
|
| 2013 |
Zhou J, Freeman TA, Ahmad F, Shang X, Mangano E, Gao E, Farber J, Wang Y, Ma XL, Woodgett J, Vagnozzi RJ, Lal H, Force T. GSK-3α is a central regulator of age-related pathologies in mice. The Journal of Clinical Investigation. 123: 1821-32. PMID 23549082 DOI: 10.1172/Jci64398 |
0.693 |
|
| 2013 |
Lal H, Kolaja KL, Force T. Cancer genetics and the cardiotoxicity of the therapeutics. Journal of the American College of Cardiology. 61: 267-74. PMID 23328609 DOI: 10.1016/J.Jacc.2012.05.066 |
0.354 |
|
| 2012 |
Vagnozzi RJ, Hoffman NE, Elrod JW, Madesh M, Force T. Protein Kinase Signaling at the Crossroads of Myocyte Life and Death in Ischemic Heart Disease. Drug Discovery Today. Therapeutic Strategies. 9: e173-e182. PMID 24839450 DOI: 10.1016/J.Ddstr.2013.12.001 |
0.749 |
|
| 2012 |
McClendon AK, Dean JL, Rivadeneira DB, Yu JE, Reed CA, Gao E, Farber JL, Force T, Koch WJ, Knudsen ES. CDK4/6 inhibition antagonizes the cytotoxic response to anthracycline therapy. Cell Cycle (Georgetown, Tex.). 11: 2747-55. PMID 22751436 DOI: 10.4161/Cc.21127 |
0.349 |
|
| 2012 |
Force T. Double-Edged Sword of the New Cancer Therapeutics Circulation. 125: 2057-2058. PMID 22451582 DOI: 10.1161/Circulationaha.112.104844 |
0.373 |
|
| 2012 |
Steingart RM, Bakris GL, Chen HX, Chen MH, Force T, Ivy SP, Leier CV, Liu G, Lenihan D, Lindenfeld J, Maitland ML, Remick SC, Tang WH. Management of cardiac toxicity in patients receiving vascular endothelial growth factor signaling pathway inhibitors. American Heart Journal. 163: 156-63. PMID 22305831 DOI: 10.1016/J.Ahj.2011.10.018 |
0.39 |
|
| 2012 |
Lal H, Zhou J, Ahmad F, Zaka R, Vagnozzi RJ, Decaul M, Woodgett J, Gao E, Force T. Glycogen synthase kinase-3α limits ischemic injury, cardiac rupture, post-myocardial infarction remodeling and death. Circulation. 125: 65-75. PMID 22086876 DOI: 10.1161/Circulationaha.111.050666 |
0.722 |
|
| 2012 |
Khakoo AY, Force T. Chapter 47 – Protein Kinases in the Heart: Lessons Learned from Targeted Cancer Therapeutics Musclefundamental Biology and Mechanisms of Disease. 689-696. DOI: 10.1016/B978-0-12-381510-1.00047-8 |
0.376 |
|
| 2011 |
Oikonomopoulos A, Sereti KI, Conyers F, Bauer M, Liao A, Guan J, Crapps D, Han JK, Dong H, Bayomy AF, Fine GC, Westerman K, Biechele TL, Moon RT, Force T, et al. Wnt signaling exerts an antiproliferative effect on adult cardiac progenitor cells through IGFBP3. Circulation Research. 109: 1363-74. PMID 22034491 DOI: 10.1161/Circresaha.111.250282 |
0.405 |
|
| 2011 |
Hernández G, Lal H, Fidalgo M, Guerrero A, Zalvide J, Force T, Pombo CM. A novel cardioprotective p38-MAPK/mTOR pathway. Experimental Cell Research. 317: 2938-49. PMID 22001647 DOI: 10.1016/J.Yexcr.2011.09.011 |
0.403 |
|
| 2011 |
Cheng H, Kari G, Dicker AP, Rodeck U, Koch WJ, Force T. A novel preclinical strategy for identifying cardiotoxic kinase inhibitors and mechanisms of cardiotoxicity Circulation Research. 109: 1401-1409. PMID 21998323 DOI: 10.1161/Circresaha.111.255695 |
0.473 |
|
| 2011 |
Kerkelä R, Boucher M, Zaka R, Gao E, Harris D, Piuhola J, Song J, Serpi R, Woulfe KC, Cheung JY, O'Leary E, Bonventre JV, Force T. Cytosolic phospholipase A(2)α protects against ischemia/reperfusion injury in the heart. Clinical and Translational Science. 4: 236-42. PMID 21884509 DOI: 10.1111/J.1752-8062.2011.00294.X |
0.663 |
|
| 2011 |
Force T, Kolaja KL. Cardiotoxicity of kinase inhibitors: the prediction and translation of preclinical models to clinical outcomes. Nature Reviews. Drug Discovery. 10: 111-26. PMID 21283106 DOI: 10.1038/Nrd3252 |
0.36 |
|
| 2011 |
Eschenhagen T, Force T, Ewer MS, de Keulenaer GW, Suter TM, Anker SD, Avkiran M, de Azambuja E, Balligand JL, Brutsaert DL, Condorelli G, Hansen A, Heymans S, Hill JA, Hirsch E, et al. Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure. 13: 1-10. PMID 21169385 DOI: 10.1093/Eurjhf/Hfq213 |
0.381 |
|
| 2011 |
McClendon K, Dean JL, Rivadeneira D, Reed CA, Witkiewicz A, Gao E, Koch WJ, Force T, Knudsen ES. Abstract 591: Expanding the therapeutic window through pharmacological activation of the RB pathway in breast cancer treatment Cancer Research. 71: 591-591. DOI: 10.1158/1538-7445.Am2011-591 |
0.327 |
|
| 2011 |
Springer J, Tschirner A, Haghika A, Grzesiak A, Kaschina E, Lal H, Haehling Sv, Hilfiker-Kleiner D, Force T, Anker SD. Cardiac Wasting in Experimental Cancer Cachexia: Prevention by Bisoprolol and Spironolactone Journal of Cardiac Failure. 17. DOI: 10.1016/J.Cardfail.2011.06.033 |
0.334 |
|
| 2010 |
Marber MS, Molkentin JD, Force T. Developing small molecules to inhibit kinases unkind to the heart: p38 MAPK as a case in point. Drug Discovery Today. Disease Mechanisms. 7: e123-e127. PMID 21278838 DOI: 10.1016/J.Ddmec.2010.07.006 |
0.486 |
|
| 2010 |
Rose BA, Force T, Wang Y. Mitogen-activated protein kinase signaling in the heart: Angels versus demons in a heart-breaking tale Physiological Reviews. 90: 1507-1546. PMID 20959622 DOI: 10.1152/Physrev.00054.2009 |
0.502 |
|
| 2010 |
Elrod JW, Wong R, Mishra S, Vagnozzi RJ, Sakthievel B, Goonasekera SA, Karch J, Gabel S, Farber J, Force T, Brown JH, Murphy E, Molkentin JD. Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice. The Journal of Clinical Investigation. 120: 3680-7. PMID 20890047 DOI: 10.1172/Jci43171 |
0.693 |
|
| 2010 |
Force T, Bonow RO, Houser SR, Solaro RJ, Hershberger RE, Adhikari B, Anderson ME, Boineau R, Byrne BJ, Cappola TP, Kalluri R, LeWinter MM, Maron MS, Molkentin JD, Ommen SR, et al. Research priorities in hypertrophic cardiomyopathy: report of a Working Group of the National Heart, Lung, and Blood Institute. Circulation. 122: 1130-3. PMID 20837938 DOI: 10.1161/Circulationaha.110.950089 |
0.394 |
|
| 2010 |
Cheng H, Force T. Why do Kinase Inhibitors Cause Cardiotoxicity and What can be Done About It Progress in Cardiovascular Diseases. 53: 114-120. PMID 20728698 DOI: 10.1016/J.Pcad.2010.06.006 |
0.421 |
|
| 2010 |
Zhou J, Lal H, Chen X, Shang X, Song J, Li Y, Kerkela R, Doble BW, MacAulay K, DeCaul M, Koch WJ, Farber J, Woodgett J, Gao E, Force T. GSK-3α directly regulates β-adrenergic signaling and the response of the heart to hemodynamic stress in mice Journal of Clinical Investigation. 120: 2280-2291. PMID 20516643 DOI: 10.1172/Jci41407 |
0.447 |
|
| 2010 |
Woulfe KC, Gao E, Lal H, Harris D, Fan Q, Vagnozzi R, DeCaul M, Shang X, Patel S, Woodgett JR, Force T, Zhou J. Glycogen synthase kinase-3beta regulates post-myocardial infarction remodeling and stress-induced cardiomyocyte proliferation in vivo. Circulation Research. 106: 1635-45. PMID 20360256 DOI: 10.1161/Circresaha.109.211482 |
0.776 |
|
| 2010 |
Fidalgo M, Fraile M, Pires A, Force T, Pombo C, Zalvide J. CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation Journal of Cell Science. 123: 1274-1284. PMID 20332113 DOI: 10.1242/Jcs.061341 |
0.311 |
|
| 2010 |
Cheng H, Force T. Molecular Mechanisms of Cardiovascular Toxicity of Targeted Cancer Therapeutics Circulation Research. 106: 21-34. PMID 20056943 DOI: 10.1161/Circresaha.109.206920 |
0.401 |
|
| 2010 |
Force T. Introduction to Cardiotoxicity Review Series Circulation Research. 106: 19-20. PMID 20056942 DOI: 10.1161/Circresaha.109.210724 |
0.371 |
|
| 2009 |
Kerkela R, Woulfe KC, Durand JB, Vagnozzi R, Kramer D, Chu TF, Beahm C, Chen MH, Force T. Sunitinib-induced cardiotoxicity is mediated by off-target inhibition of AMP-activated protein kinase. Clinical and Translational Science. 2: 15-25. PMID 20376335 DOI: 10.1111/J.1752-8062.2008.00090.X |
0.793 |
|
| 2009 |
Zhou J, Shao Z, Kerkela R, Ichijo H, Muslin AJ, Pombo C, Force T. Serine 58 of 14-3-3zeta is a molecular switch regulating ASK1 and oxidant stress-induced cell death. Molecular and Cellular Biology. 29: 4167-76. PMID 19451227 DOI: 10.1128/Mcb.01067-08 |
0.377 |
|
| 2009 |
Force T, Woodgett JR. Unique and overlapping functions of GSK-3 isoforms in cell differentiation and proliferation and cardiovascular development. The Journal of Biological Chemistry. 284: 9643-7. PMID 19064989 DOI: 10.1074/Jbc.R800077200 |
0.376 |
|
| 2008 |
Kerkela R, Kockeritz L, Macaulay K, Zhou J, Doble BW, Beahm C, Greytak S, Woulfe K, Trivedi CM, Woodgett JR, Epstein JA, Force T, Huggins GS. Deletion of GSK-3beta in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation. The Journal of Clinical Investigation. 118: 3609-18. PMID 18830417 DOI: 10.1172/Jci36245 |
0.716 |
|
| 2008 |
Chen MH, Kerkelä R, Force T. Mechanisms of Cardiac Dysfunction Associated With Tyrosine Kinase Inhibitor Cancer Therapeutics Circulation. 118: 84-95. PMID 18591451 DOI: 10.1161/Circulationaha.108.776831 |
0.438 |
|
| 2008 |
Patten RD, Pourati I, Aronovitz MJ, Alsheikh-Ali A, Eder S, Force T, Mendelsohn ME, Karas RH. 17 Beta-estradiol differentially affects left ventricular and cardiomyocyte hypertrophy following myocardial infarction and pressure overload. Journal of Cardiac Failure. 14: 245-53. PMID 18381189 DOI: 10.1016/J.Cardfail.2007.10.024 |
0.396 |
|
| 2008 |
Nogueira E, Fidalgo M, Molnar A, Kyriakis J, Force T, Zalvide J, Pombo CM. SOK1 translocates from the Golgi to the nucleus upon chemical anoxia and induces apoptotic cell death. The Journal of Biological Chemistry. 283: 16248-58. PMID 18364353 DOI: 10.1074/Jbc.M709724200 |
0.363 |
|
| 2008 |
Force T. The weakness of a big heart Nature Medicine. 14: 244-245. PMID 18323842 DOI: 10.1038/Nm0308-244 |
0.478 |
|
| 2007 |
Chu TF, Rupnick MA, Kerkela R, Dallabrida SM, Zurakowski D, Nguyen L, Woulfe K, Pravda E, Cassiola F, Desai J, George S, Morgan JA, Harris DM, Ismail NS, Chen JH, ... ... Force T, et al. Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib. Lancet (London, England). 370: 2011-9. PMID 18083403 DOI: 10.1016/S0140-6736(07)61865-0 |
0.694 |
|
| 2007 |
Liao R, Force T. Not all hypertrophy is created equal Circulation Research. 101: 1069-1072. PMID 18040021 DOI: 10.1161/Circresaha.107.165621 |
0.485 |
|
| 2007 |
Force T, Woulfe K, Koch WJ, Kerkelä R. Molecular scaffolds regulate bidirectional crosstalk between Wnt and classical seven-transmembrane-domain receptor signaling pathways. Science Signaling. 2007. PMID 17666710 DOI: 10.1126/Stke.3972007Pe41 |
0.664 |
|
| 2007 |
Force T, Krause DS, Van Etten RA. Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition. Nature Reviews. Cancer. 7: 332-44. PMID 17457301 DOI: 10.1038/Nrc2106 |
0.434 |
|
| 2007 |
Kerkelä R, Woulfe K, Force T. Glycogen Synthase Kinase-3β—Actively Inhibiting Hypertrophy Trends in Cardiovascular Medicine. 17: 91-96. PMID 17418370 DOI: 10.1016/J.Tcm.2007.01.004 |
0.746 |
|
| 2007 |
Pombo CM, Force T, Kyriakis J, Nogueira E, Fidalgo M, Zalvide J. The GCK II and III subfamilies of the STE20 group kinases. Frontiers in Bioscience. 12: 850. PMID 17127342 DOI: 10.2741/2107 |
0.361 |
|
| 2007 |
Goruppi S, Patten RD, Force T, Kyriakis JM. Helix-loop-helix protein p8, a transcriptional regulator required for cardiomyocyte hypertrophy and cardiac fibroblast matrix metalloprotease induction Molecular and Cellular Biology. 27: 993-1006. PMID 17116693 DOI: 10.1128/Mcb.00996-06 |
0.415 |
|
| 2007 |
Force TL. Heart Failure: Molecules, Mechanisms and Therapeutic Targets Circulation. 115. DOI: 10.1161/Circulationaha.106.674127 |
0.375 |
|
| 2006 |
Shevtsov SP, Haq S, Force T. Activation of β-catenin signaling pathways by classical G-protein-coupled receptors : Mechanisms and consequences in cycling and non-cycling cells Cell Cycle. 5: 2295-2300. PMID 17035736 DOI: 10.4161/Cc.5.20.3357 |
0.316 |
|
| 2006 |
Kerkela R, Force T. p38 mitogen-activated protein kinase: a future target for heart failure therapy? Journal of the American College of Cardiology. 48: 556-558. PMID 16875983 DOI: 10.1016/J.Jacc.2006.05.005 |
0.431 |
|
| 2006 |
Kerkelä R, Grazette L, Yacobi R, Iliescu C, Patten R, Beahm C, Walters B, Shevtsov S, Pesant S, Clubb FJ, Rosenzweig A, Salomon RN, Van Etten RA, Alroy J, Durand JB, ... Force T, et al. Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. Nature Medicine. 12: 908-16. PMID 16862153 DOI: 10.1038/Nm1446 |
0.407 |
|
| 2006 |
Xu D, Patten RD, Force T, Kyriakis JM. Gene 33/RALT is induced by hypoxia in cardiomyocytes, where it promotes cell death by suppressing phosphatidylinositol 3-kinase and extracellular signal-regulated kinase survival signaling Molecular and Cellular Biology. 26: 5043-5054. PMID 16782890 DOI: 10.1128/Mcb.02387-05 |
0.446 |
|
| 2006 |
Chen X, Shevtsov SP, Hsich E, Cui L, Haq S, Aronovitz M, Kerkelä R, Molkentin JD, Liao R, Salomon RN, Patten R, Force T. The β-catenin/T-cell factor/lymphocyte enhancer factor signaling pathway is required for normal and stress-induced cardiac hypertrophy Molecular and Cellular Biology. 26: 4462-4473. PMID 16738313 DOI: 10.1128/Mcb.02157-05 |
0.396 |
|
| 2006 |
Kerkela R, Force T. Recent insights into cardiac hypertrophy and left ventricular remodeling. Current Heart Failure Reports. 3: 14-18. PMID 16684492 DOI: 10.1007/S11897-006-0026-6 |
0.441 |
|
| 2006 |
Massie BM, Force T. The year in heart failure 2005 Journal of Cardiac Failure. 12: 1-9. PMID 16500577 DOI: 10.1016/J.Cardfail.2006.01.001 |
0.32 |
|
| 2006 |
Shao Z, Bhattacharya K, Hsich E, Park L, Walters B, Germann U, Wang YM, Kyriakis J, Mohanlal R, Kuida K, Namchuk M, Salituro F, Yao YM, Hou WM, Chen X, ... ... Force T, et al. c-Jun N-terminal kinases mediate reactivation of Akt and cardiomyocyte survival after hypoxic injury in vitro and in vivo. Circulation Research. 98: 111-8. PMID 16306447 DOI: 10.1161/01.Res.0000197781.20524.B9 |
0.472 |
|
| 2005 |
Liu E, Sinha S, Williams C, Cyrille M, Heller E, Snapper SB, Georgopoulos K, St-Arnaud R, Force T, Dedhar S, Gerszten RE. Targeted deletion of integrin-linked kinase reveals a role in T-cell chemotaxis and survival. Molecular and Cellular Biology. 25: 11145-55. PMID 16314534 DOI: 10.1128/Mcb.25.24.11145-11155.2005 |
0.406 |
|
| 2005 |
Dorn GW, Force T. Protein kinase cascades in the regulation of cardiac hypertrophy. The Journal of Clinical Investigation. 115: 527-37. PMID 15765134 DOI: 10.1172/Jci24178 |
0.442 |
|
| 2005 |
Liu P, Konstam MA, Force T. Highlights of the 2004 scientific sessions of the Heart Failure Society of America, Toronto, Canada, September 12 to 15, 2004. Journal of the American College of Cardiology. 45: 617-625. PMID 15708712 DOI: 10.1016/J.Jacc.2004.11.059 |
0.312 |
|
| 2005 |
Skurk C, Maatz H, Rocnik E, Bialik A, Force T, Walsh K. Glycogen-Synthase Kinase3beta/beta-catenin axis promotes angiogenesis through activation of vascular endothelial growth factor signaling in endothelial cells. Circulation Research. 96: 308-18. PMID 15662032 DOI: 10.1161/01.Res.0000156273.30274.F7 |
0.355 |
|
| 2004 |
Patten RD, Pourati I, Aronovitz MJ, Baur J, Celestin F, Chen X, Michael A, Haq S, Nuedling S, Grohe C, Force T, Mendelsohn ME, Karas RH. 17β-estradiol reduces cardiomyocyte apoptosis in vivo and in vitro via activation of phospho-inositide-3 kinase/Akt signaling Circulation Research. 95: 692-699. PMID 15345655 DOI: 10.1161/01.Res.0000144126.57786.89 |
0.439 |
|
| 2004 |
Friedrich EB, Liu E, Sinha S, Cook S, Milstone DS, MacRae CA, Mariotti M, Kuhlencordt PJ, Force T, Rosenzweig A, St-Arnaud R, Dedhar S, Gerszten RE. Integrin-linked kinase regulates endothelial cell survival and vascular development. Molecular and Cellular Biology. 24: 8134-44. PMID 15340074 DOI: 10.1128/Mcb.24.18.8134-8144.2004 |
0.398 |
|
| 2004 |
Liu P, Konstam MA, Force T, Yano C. Highlights of the 2003 scientific sessions of the Heart Failure Society of America: Las Vegas, Nevada, September 21 to 24, 2003 Journal of the American College of Cardiology. 43: 1103-1109. PMID 15028374 DOI: 10.1016/J.Jacc.2004.01.026 |
0.319 |
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| 2004 |
Force T, Kuida K, Namchuk M, Parang K, Kyriakis JM. Inhibitors of protein kinase signaling pathways: emerging therapies for cardiovascular disease. Circulation. 109: 1196-205. PMID 15023894 DOI: 10.1161/01.Cir.0000118538.21306.A9 |
0.432 |
|
| 2004 |
Michael A, Haq S, Chen X, Hsich E, Cui L, Walters B, Shao Z, Bhattacharya K, Kilter H, Huggins G, Andreucci M, Periasamy M, Solomon RN, Liao R, Patten R, ... ... Force T, et al. Glycogen synthase kinase-3beta regulates growth, calcium homeostasis, and diastolic function in the heart. The Journal of Biological Chemistry. 279: 21383-93. PMID 15020584 DOI: 10.1074/Jbc.M401413200 |
0.431 |
|
| 2003 |
Andreucci M, Michael A, Kramers C, Park KM, Chen A, Matthaeus T, Alessandrini A, Haq S, Force T, Bonventre JV. Renal ischemia/reperfusion and ATP depletion/repletion in LLC-PK1 cells result in phosphorylation of FKHR and FKHRL1 Kidney International. 64: 1189-1198. PMID 12969136 DOI: 10.1046/J.1523-1755.2003.00204.X |
0.425 |
|
| 2003 |
Haq S, Kilter H, Michael A, Tao J, O'Leary E, Sun XM, Walters B, Bhattacharya K, Chen X, Cui L, Andreucci M, Rosenzweig A, Guerrero JL, Patten R, Liao R, ... ... Force T, et al. Deletion of cytosolic phospholipase A2 promotes striated muscle growth Nature Medicine. 9: 944-951. PMID 12808451 DOI: 10.1038/Nm891 |
0.363 |
|
| 2003 |
Lee HY, Srinivas H, Xia D, Lu Y, Superty R, LaPushin R, Gomez-Manzano C, Gal AM, Walsh GL, Force T, Ueki K, Mills GB, Kurie JM. Evidence that phosphatidylinositol 3-kinase- and mitogen-activated protein kinase kinase-4/c-Jun NH2-terminal kinase-dependent Pathways cooperate to maintain lung cancer cell survival. The Journal of Biological Chemistry. 278: 23630-8. PMID 12714585 DOI: 10.1074/Jbc.M300997200 |
0.414 |
|
| 2003 |
Haq S, Michael A, Andreucci M, Bhattacharya K, Dotto P, Walters B, Woodgett J, Kilter H, Force T. Stabilization of beta-catenin by a Wnt-independent mechanism regulates cardiomyocyte growth. Proceedings of the National Academy of Sciences of the United States of America. 100: 4610-5. PMID 12668767 DOI: 10.1073/Pnas.0835895100 |
0.313 |
|
| 2003 |
Force T, Michael A, Kilter H, Haq S. Stretch-activated pathways and left ventricular remodeling. Journal of Cardiac Failure. 8: S351-8. PMID 12555145 DOI: 10.1054/jcaf.2002.129272 |
0.322 |
|
| 2002 |
Friedrich EB, Sinha S, Li L, Dedhar S, Force T, Rosenzweig A, Gerszten RE. Role of integrin-linked kinase in leukocyte recruitment. The Journal of Biological Chemistry. 277: 16371-5. PMID 11856758 DOI: 10.1074/Jbc.M201240200 |
0.378 |
|
| 2002 |
Force T, Haq S, Kilter H, Michael A. Apoptosis signal-regulating kinase/nuclear factor-κB: A novel signaling pathway regulates cardiomyocyte hypertrophy Circulation. 105: 402-404. DOI: 10.1161/Circ.105.4.402 |
0.444 |
|
| 2001 |
Matsui T, Tao J, Monte Fd, Lee K, Li L, Picard M, Force TL, Franke TF, Hajjar RJ, Rosenzweig A. Akt Activation Preserves Cardiac Function and Prevents Injury After Transient Cardiac Ischemia In Vivo Circulation. 104: 330-335. PMID 11457753 DOI: 10.1161/01.Cir.104.3.330 |
0.498 |
|
| 2001 |
Dong Z, Venkatachalam MA, Wang J, Patel Y, Saikumar P, Semenza GL, Force T, Nishiyama J. Up-regulation of apoptosis inhibitory protein IAP-2 by hypoxia. Hif-1-independent mechanisms. The Journal of Biological Chemistry. 276: 18702-9. PMID 11278985 DOI: 10.1074/Jbc.M011774200 |
0.342 |
|
| 2001 |
Gerszten RE, Friedrich EB, Matsui T, Hung RR, Li L, Force T, Rosenzweig A. Role of phosphoinositide 3-kinase in monocyte recruitment under flow conditions. Journal of Biological Chemistry. 276: 26846-26851. PMID 11278864 DOI: 10.1074/Jbc.M011235200 |
0.344 |
|
| 2001 |
Haq S, Choukroun G, Lim H, Tymitz KM, del Monte F, Gwathmey J, Grazette L, Michael A, Hajjar R, Force T, Molkentin JD. Differential activation of signal transduction pathways in human hearts with hypertrophy versus advanced heart failure. Circulation. 103: 670-7. PMID 11156878 DOI: 10.1161/01.Cir.103.5.670 |
0.475 |
|
| 2000 |
Volloch V, Gabai VL, Rits S, Force T, Sherman MY. HSP72 can protect cells from heat-induced apoptosis by accelerating the inactivation of stress kinase JNK. Cell Stress & Chaperones. 5: 139-147. PMID 11147965 DOI: 10.1379/1466-1268(2000)005<0139:Hcpcfh>2.0.Co;2 |
0.307 |
|
| 2000 |
Haq S, Choukroun G, Kang ZB, Ranu H, Matsui T, Rosenzweig A, Molkentin JD, Alessandrini A, Woodgett J, Hajjar R, Michael A, Force T. Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy. The Journal of Cell Biology. 151: 117-30. PMID 11018058 DOI: 10.1083/Jcb.151.1.117 |
0.425 |
|
| 2000 |
Gabai VL, Yaglom JA, Volloch V, Meriin AB, Force T, Koutroumanis M, Massie B, Mosser DD, Sherman MY. Hsp72-mediated suppression of c-Jun N-terminal kinase is implicated in development of tolerance to caspase-independent cell death Molecular and Cellular Biology. 20: 6826-6836. PMID 10958679 DOI: 10.1128/Mcb.20.18.6826-6836.2000 |
0.39 |
|
| 2000 |
De Windt LJ, Lim HW, Haq S, Force T, Molkentin JD. Calcineurin promotes protein kinase C and c-Jun NH2-terminal kinase activation in the heart. Cross-talk between cardiac hypertrophic signaling pathways. The Journal of Biological Chemistry. 275: 13571-9. PMID 10788473 DOI: 10.1074/Jbc.275.18.13571 |
0.48 |
|
| 2000 |
Lee K, Hajjar RJ, Matsui T, Choukroun G, Force TL, Rosenzweig A. Cardiac signal transduction. Journal of Nuclear Cardiology. 7: 63-71. PMID 10698236 DOI: 10.1067/Mnc.2000.103724 |
0.389 |
|
| 1999 |
Choukroun G, Hajjar R, Fry S, Monte FD, Haq S, Guerrero JL, Picard MH, Rosenzweig A, Force T. Regulation of cardiac hypertrophy in vivo by the stress-activated protein kinases/c-Jun NH2-terminal kinases Journal of Clinical Investigation. 104: 391-398. PMID 10449431 DOI: 10.1172/Jci6350 |
0.487 |
|
| 1999 |
Quinn D, Tager A, Joseph PM, Bonventre JV, Force T, Hales CA. Stretch-induced mitogen-activated protein kinase activation and interleukin-8 production in type II alveolar cells. Chest. 116: 89. PMID 10424608 DOI: 10.1378/Chest.116.Suppl_1.89S |
0.338 |
|
| 1999 |
Force T, Rosenzweig A, Choukroun G, Hajjar R. Calcineurin inhibitors and cardiac hypertrophy. The Lancet. 353: 1290-1292. PMID 10218524 DOI: 10.1016/S0140-6736(99)90016-8 |
0.411 |
|
| 1998 |
Choukroun G, Hajjar R, Kyriakis JM, Bonventre JV, Rosenzweig A, Force T. Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy Journal of Clinical Investigation. 102: 1311-1320. PMID 9769323 DOI: 10.1172/Jci3512 |
0.418 |
|
| 1998 |
Bonventre JV, Force T. Mitogen-activated protein kinases and transcriptional responses in renal injury and repair. Current Opinion in Nephrology and Hypertension. 7: 425-434. PMID 9690043 DOI: 10.1097/00041552-199807000-00013 |
0.41 |
|
| 1998 |
Force T, Bonventre JV. Growth Factors and Mitogen-Activated Protein Kinases Hypertension. 31: 152-161. PMID 9453296 DOI: 10.1161/01.Hyp.31.1.152 |
0.4 |
|
| 1997 |
Pombo CM, Tsujita T, Kyriakis JM, Bonventre JV, Force T. Activation of the Ste20-like oxidant stress response kinase-1 during the initial stages of chemical anoxia-induced necrotic cell death. Requirement for dual inputs of oxidant stress and increased cytosolic [Ca2+] Journal of Biological Chemistry. 272: 29372-29379. PMID 9361019 DOI: 10.1074/Jbc.272.46.29372 |
0.341 |
|
| 1996 |
Bonventre JV, Kyriakis JM, Spech R, Witzgall R, Force T. Phospholipase A(2) and Lipids as Potential Modulators of c-Raf-1 Kinase. American Journal of Therapeutics. 3: 287-293. PMID 11862263 DOI: 10.1097/00045391-199604000-00006 |
0.335 |
|
| 1996 |
Force T, Pombo CM, Avruch JA, Bonventre JV, Kyriakis JM. Stress-activated protein kinases in cardiovascular disease Circulation Research. 78: 947-953. PMID 8635244 DOI: 10.1161/01.Res.78.6.947 |
0.427 |
|
| 1996 |
Pombo CM, Bonventre JV, Molnar A, Kyriakis J, Force T. Activation of a human Ste20‐like kinase by oxidant stress defines a novel stress response pathway. The Embo Journal. 15: 4537-4546. DOI: 10.1002/J.1460-2075.1996.Tb00831.X |
0.363 |
|
| 1995 |
Morooka H, Bonventre JV, Pombo CM, Kyriakis JM, Force T. Ischemia and reperfusion enhance ATF-2 and c-Jun binding to cAMP response elements and to an AP-1 binding site from the c-jun promoter Journal of Biological Chemistry. 270: 30084-30092. PMID 8530413 DOI: 10.1074/Jbc.270.50.30084 |
0.364 |
|
| 1995 |
Pombo CM, Kehrl JH, Sánchez I, Katz P, Avruch J, Zon LI, Woodgett JR, Force T, Kyriakis JM. Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase Nature. 377: 750-754. PMID 7477268 DOI: 10.1038/377750A0 |
0.4 |
|
| 1994 |
Davidoff R, Picard MH, Force T, Thomas JD, Guerrero JL, McGlew S, Weyman AE. Spatial and temporal variability in the pattern of recovery of ventricular geometry and function after acute occlusion and reperfusion. American Heart Journal. 127: 1231-41. PMID 8172051 DOI: 10.1016/0002-8703(94)90041-8 |
0.339 |
|
| 1994 |
Force T, Bonventre JV, Heidecker G, Rapp U, Avruch J, Kyriakis JM. Enzymatic characteristics of the c-Raf-1 protein kinase Proceedings of the National Academy of Sciences of the United States of America. 91: 1270-1274. PMID 8108400 DOI: 10.1073/Pnas.91.4.1270 |
0.346 |
|
| 1988 |
Kemper A, Force T, Gilfoil M, Perkins LA, Parisi AF. Topographic correspondence of contrast echocardiographic perfusion mapping and myocardial infarct extent after varying durations of coronary occlusion. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 1: 104-13. PMID 3272755 DOI: 10.1016/S0894-7317(88)80091-9 |
0.315 |
|
| 1986 |
Kemper AJ, Force T, Perkins L, Gilfoil M, Parisi AF. In vivo prediction of the transmural extent of experimental acute myocardial infarction using contrast echocardiography. Journal of the American College of Cardiology. 8: 143-149. PMID 3711509 DOI: 10.1016/S0735-1097(86)80105-X |
0.303 |
|
| 1985 |
Force T, Kemper AJ, Cohen C, Parisi AF. Early loss of postextrasystolic potentiation in acutely ischemic myocardium: evaluation by contrast two-dimensional echocardiography. Circulation. 71: 602-609. PMID 2578903 DOI: 10.1161/01.Cir.71.3.602 |
0.301 |
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