Diane M. Simeone - Publications

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Cell Biology

230 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Werba G, Weissinger D, Kawaler EA, Zhao E, Kalfakakou D, Dhara S, Wang L, Lim HB, Oh G, Jing X, Beri N, Khanna L, Gonda T, Oberstein P, Hajdu C, ... ... Simeone DM, et al. Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment. Nature Communications. 14: 797. PMID 36781852 DOI: 10.1038/s41467-023-36296-4  0.31
2022 Pan S, Lai LA, Simeone DM, Dawson DW, Yan Y, Crnogorac-Jurcevic T, Chen R, Brentnall TA. Proteomes of Extracellular Vesicles From Pancreatic Cancer Cells and Cancer-Associated Fibroblasts. Pancreas. 51: 790-799. PMID 36395405 DOI: 10.1097/MPA.0000000000002115  0.37
2022 Xu J, Yang R, Li J, Wang L, Cohen M, Simeone DM, Costa M, Wu XR. DNMT3A//Rac1 Is an Effector Pathway for to Drive Stem-Cell-like and Invasive Behaviors of Advanced Bladder Cancer Cells. Cancers. 14. PMID 36077697 DOI: 10.3390/cancers14174159  0.3
2021 Gonda TA, Farrell J, Wallace M, Khanna L, Janec E, Kwon R, Saunders M, Siddiqui U, Brand R, Simeone D. Standardization of EUS imaging and reporting in high-risk individuals of pancreatic adenocarcinoma: consensus statement of the Pancreatic Cancer Early Detection Consortium (PRECEDE). Gastrointestinal Endoscopy. PMID 34736932 DOI: 10.1016/j.gie.2021.10.025  0.306
2021 Gonda TA, Everett JN, Wallace M, Simeone DM. Recommendations for a More Organized and Effective Approach to the Early Detection of Pancreatic Cancer From the PRECEDE (Pancreatic Cancer Early Detection) Consortium. Gastroenterology. 161: 1751-1757. PMID 34454916 DOI: 10.1053/j.gastro.2021.08.036  0.319
2021 Purohit V, Wang L, Yang H, Li J, Ney GM, Gumkowski ER, Vaidya AJ, Wang A, Bhardwaj A, Zhao E, Dolgalev I, Zamperone A, Abel EV, Magliano MPD, Crawford HC, ... ... Simeone DM, et al. ATDC binds to KEAP1 to drive NRF2-mediated tumorigenesis and chemoresistance in pancreatic cancer. Genes & Development. PMID 33446568 DOI: 10.1101/gad.344184.120  0.319
2020 Grant RC, Denroche R, Jang GH, Nowak KM, Zhang A, Borgida A, Holter S, Topham JT, Wilson J, Dodd A, Jang R, Prince R, Karasinska JM, Schaeffer DF, Wang Y, ... ... Simeone D, et al. Clinical and genomic characterisation of mismatch repair deficient pancreatic adenocarcinoma. Gut. PMID 32933947 DOI: 10.1136/Gutjnl-2020-320730  0.337
2020 Gout J, Perkhofer L, Morawe M, Arnold F, Ihle M, Biber S, Lange S, Roger E, Kraus JM, Stifter K, Hahn SA, Zamperone A, Engleitner T, Müller M, Walter K, ... ... Simeone DM, et al. Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer. Gut. PMID 32873698 DOI: 10.1136/Gutjnl-2019-319970  0.339
2020 Grossberg AJ, Chu LC, Deig CR, Fishman EK, Hwang WL, Maitra A, Marks DL, Mehta A, Nabavizadeh N, Simeone DM, Weekes CD, Thomas CR. Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma. Ca: a Cancer Journal For Clinicians. PMID 32683683 DOI: 10.3322/Caac.21626  0.339
2020 Brunton H, Caligiuri G, Cunningham R, Upstill-Goddard R, Bailey UM, Garner IM, Nourse C, Dreyer S, Jones M, Moran-Jones K, Wright DW, Paulus-Hock V, Nixon C, Thomson G, Jamieson NB, ... ... Simeone DM, et al. HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer. Cell Reports. 31: 107625. PMID 32402285 DOI: 10.1016/J.Celrep.2020.107625  0.378
2019 Wan S, Kim TH, Smith KJ, Delaney R, Park GS, Guo H, Lin E, Plegue T, Kuo N, Steffes J, Leu C, Simeone DM, Razimulava N, Parikh ND, Nagrath S, et al. New Labyrinth Microfluidic Device Detects Circulating Tumor Cells Expressing Cancer Stem Cell Marker and Circulating Tumor Microemboli in Hepatocellular Carcinoma. Scientific Reports. 9: 18575. PMID 31819089 DOI: 10.1038/S41598-019-54960-Y  0.334
2019 Majumder S, Taylor WR, Yab TC, Berger CK, Dukek BA, Cao X, Foote PH, Wu CW, Mahoney DW, Aslanian HR, Fernández-Del Castillo C, Doyle LA, Farrell JJ, Fisher WE, Lee LS, ... ... Simeone DM, et al. Novel Methylated DNA Markers Discriminate Advanced Neoplasia in Pancreatic Cysts: Marker Discovery, Tissue Validation, and Cyst Fluid Testing. The American Journal of Gastroenterology. PMID 31306149 DOI: 10.14309/Ajg.0000000000000284  0.382
2019 Bulin AL, Broekgaarden M, Simeone D, Hasan T. Low dose photodynamic therapy harmonizes with radiation therapy to induce beneficial effects on pancreatic heterocellular spheroids. Oncotarget. 10: 2625-2643. PMID 31080554 DOI: 10.18632/Oncotarget.26780  0.35
2019 Pratt ED, Cowan RW, Manning SL, Qiao E, Cameron H, Schradle K, Simeone DM, Zhen DB. Multiplex Enrichment and Detection of Rare KRAS Mutations in Liquid Biopsy Samples using Digital Droplet Pre-Amplification. Analytical Chemistry. 91: 7516-7523. PMID 31072097 DOI: 10.1021/Acs.Analchem.8B01605  0.302
2019 Palmbos PL, Wang Y, Bankhead Iii A, Kelleher AJ, Wang L, Yang H, Ahmet ML, Gumkowski ER, Welling SD, Magnuson B, Leflein J, Lorenzatti Hiles G, Abel EV, Dziubinski ML, Urs S, ... ... Simeone DM, et al. ATDC mediates a TP63-regulated basal cancer invasive program. Oncogene. PMID 30643195 DOI: 10.1038/S41388-018-0646-9  0.398
2019 Wang A, Zamperone A, Sohail M, Wang L, Balogun F, Li J, Zhao E, Diolaiti D, Sfeir A, Simeone DM. Abstract I14: Polymerase theta synthetic lethal interaction in homologous recombination-deficient pancreatic ductal adenocarcinoma Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-I14  0.387
2019 Fernandez-Zapico M, Kim DW, Philip P, Vandell A, Eckard J, Korn R, Priore GD, Simeone D. Abstract B15: Therapeutic potential of targeting amino acid metabolism in pancreatic cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-B15  0.446
2018 Wang Y, Day ML, Simeone DM, Palmbos PL. 3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer. Journal of Visualized Experiments : Jove. PMID 30272657 DOI: 10.3791/58345  0.43
2018 Maust JD, Frankowski-McGregor CL, Bankhead A, Simeone DM, Sebolt-Leopold JS. Cyclooxygenase-2 Influences Response to Cotargeting of MEK and CDK4/6 in a Subpopulation of Pancreatic Cancers. Molecular Cancer Therapeutics. 17: 2495-2506. PMID 30254182 DOI: 10.1158/1535-7163.Mct-18-0082  0.459
2018 Abel EV, Goto M, Magnuson B, Abraham S, Ramanathan N, Hotaling E, Alaniz AA, Kumar-Sinha C, Dziubinski ML, Urs S, Wang L, Shi J, Waghray M, Ljungman M, Crawford HC, ... Simeone DM, et al. HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties. Elife. 7. PMID 30074477 DOI: 10.7554/Elife.33947  0.342
2018 Zeinali M, Murlidhar V, Fouladdel S, Hafner M, Shao S, Zhao L, Cameron H, Bankhead AI, Shi J, Cuneo KC, Sahai V, Azizi E, Wicha MS, Simeone DM, Nagrath S. Abstract 5579: Increased number of EMT-like CTCs relative to epithelial CTCs reveals signatures of poor outcomes in pancreatic cancer Cancer Research. 78: 5579-5579. DOI: 10.1158/1538-7445.Am2018-5579  0.433
2017 Picozzi V, Sahai V, Simeone D, Rocha Lima C, Ocean A, Philip P, Saif W, Kalyan A, Ondovik M, Shiansong Li J, Louis C. A phase 1/2 study of metronomic 5-fluorouracil (5-FU) plus nab-paclitaxel, bevacizumab, leucovorin, and oxaliplatin (FABLOx) in patients with metastatic pancreatic cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 28: iii81-iii82. PMID 32136032 DOI: 10.1093/Annonc/Mdx261.229  0.422
2017 Pal A, Dziubinski M, Di Magliano MP, Simeone DM, Owens S, Thomas D, Peterson L, Potu H, Talpaz M, Donato NJ. Usp9x Promotes Survival in Human Pancreatic Cancer and Its Inhibition Suppresses Pancreatic Ductal Adenocarcinoma In Vivo Tumor Growth. Neoplasia (New York, N.Y.). 20: 152-164. PMID 29248719 DOI: 10.1016/J.Neo.2017.11.007  0.408
2017 Lin E, Rivera-Báez L, Fouladdel S, Yoon HJ, Guthrie S, Wieger J, Deol Y, Keller E, Sahai V, Simeone DM, Burness ML, Azizi E, Wicha MS, Nagrath S. High-Throughput Microfluidic Labyrinth for the Label-free Isolation of Circulating Tumor Cells. Cell Systems. PMID 28941584 DOI: 10.1016/J.Cels.2017.08.012  0.374
2017 Jack R, Hussain K, Rodrigues D, Zeinali M, Azizi E, Wicha M, Simeone DM, Nagrath S. Microfluidic continuum sorting of sub-populations of tumor cells via surface antibody expression levels. Lab On a Chip. PMID 28294230 DOI: 10.1039/C6Lc01496H  0.392
2017 Cuneo KC, Morgan M, Schipper MJ, Maybaum J, Al-Hawary M, Simeone DM, Sahai V, Zalupski M, Lawrence TS. Phase I study of definitive chemoradiation with gemcitabine and the WEE1 inhibitor AZD1775 in unresectable pancreatic cancer. Journal of Clinical Oncology. 35. DOI: 10.1200/Jco.2017.35.4_Suppl.Tps512  0.438
2017 Everett J, Schradle K, Cameron H, Patel A, Koeppe E, Stoffel EM, Simeone DM. Effectiveness of tablet family history collection in a multidisciplinary pancreatic tumor clinic in identifying patients with risk factors for hereditary cancer. Journal of Clinical Oncology. 35. DOI: 10.1200/Jco.2017.35.15_Suppl.E13020  0.386
2017 Majumder S, Taylor WR, Yab TC, Berger CK, Dukek BA, Cao X, Foote PH, Mahoney DW, Aslanian HR, Doyle L, Farrell JJ, Fisher WE, Lee LS, Lee YN, Park WG, ... ... Simeone DM, et al. Novel DNA Methylation Markers Assayed from Cyst Fluid Accurately Detect Advanced Neoplasia in Pancreatic Cysts: A Multicenter Study Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)30821-1  0.315
2016 Wilson RH, Chandra M, Scheiman JM, Lee SY, Lee OE, McKenna BJ, Simeone DM, Taylor JM, Mycek MA. Tissue Classification Using Optical Spectroscopy Accurately Differentiates Cancer and Chronic Pancreatitis. Pancreas. PMID 27861201 DOI: 10.1097/Mpa.0000000000000732  0.412
2016 Jack RM, Grafton MM, Rodrigues D, Giraldez MD, Griffith C, Cieslak R, Zeinali M, Kumar Sinha C, Azizi E, Wicha M, Tewari M, Simeone DM, Nagrath S. Ultra-Specific Isolation of Circulating Tumor Cells Enables Rare-Cell RNA Profiling. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 3: 1600063. PMID 27711257 DOI: 10.1002/Advs.201600063  0.357
2016 Miller MS, Allen P, Brentnall TA, Goggins M, Hruban RH, Petersen GM, Rao CV, Whitcomb DC, Brand RE, Chari ST, Klein AP, Lubman DM, Rhim AD, Simeone DM, Wolpin BM, et al. Pancreatic Cancer Chemoprevention Translational Workshop: Meeting Report. Pancreas. 45: 1080-91. PMID 27518363 DOI: 10.1097/Mpa.0000000000000705  0.449
2016 Zhen DB, Griffith KA, Ruch JM, Camphausen K, Savage JE, Kim EJ, Sahai V, Simeone DM, Zalupski MM. A phase I trial of cabozantinib and gemcitabine in advanced pancreatic cancer. Investigational New Drugs. PMID 27439894 DOI: 10.1007/S10637-016-0376-1  0.319
2016 Zhang Y, Velez-Delgado A, Mathew E, Li D, Mendez FM, Flannagan K, Rhim AD, Simeone DM, Beatty GL, Pasca di Magliano M. Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer. Gut. PMID 27402485 DOI: 10.1136/Gutjnl-2016-312078  0.372
2016 Nagrath S, Jack RM, Sahai V, Simeone DM. Opportunities and Challenges for Pancreatic Circulating Tumor Cells Gastroenterology. 151: 412-426. PMID 27339829 DOI: 10.1053/J.Gastro.2016.05.052  0.44
2016 Coveler AL, Herman JM, Simeone DM, Chiorean EG. Localized Pancreatic Cancer: Multidisciplinary Management. American Society of Clinical Oncology Educational Book / Asco. American Society of Clinical Oncology. Meeting. 35: e217-26. PMID 27249726 DOI: 10.14694/EDBK_160827  0.31
2016 Waghray M, Yalamanchili M, Dziubinski M, Zeinali M, Erkkinen M, Yang H, Schradle KA, Urs S, Pasca Di Magliano M, Welling TH, Palmbos PL, Abel EV, Sahai V, Nagrath S, Wang L, ... Simeone DM, et al. GM-CSF Mediates Mesenchymal-Epithelial Crosstalk in Pancreatic Cancer. Cancer Discovery. PMID 27184426 DOI: 10.1158/2159-8290.Cd-15-0947  0.43
2016 Kwon RS, Young BE, Marsteller WF, Lawrence C, Wu BU, Lee LS, Mullady D, Klibansky DA, Gardner TB, Simeone DM. Narcotic Independence After Pancreatic Duct Stenting Predicts Narcotic Independence After Lateral Pancreaticojejunostomy for Chronic Pancreatitis. Pancreas. PMID 27088488 DOI: 10.1097/Mpa.0000000000000623  0.321
2016 Majumder S, Taylor WR, Yab TC, Berger CK, Mahoney DW, Aslanian HR, Farrell JJ, Fisher WE, Rothberg BG, Salem RR, Simeone DM, Buren GJV, Raimondo M, Chari ST, Kisiel JB, et al. Detection of Advanced Neoplasia in Pancreatic Cysts by Assay of Novel DNA Methylation Markers in Cyst Fluid: A Multicenter Pilot Study: 2016 ACG Fellows-In-Training Award (Biliary/Pancreas Category): 2 The American Journal of Gastroenterology. 111. DOI: 10.14309/00000434-201610001-00002  0.312
2016 Zhen DB, Griffith KA, Ruch JM, Morgan M, Kim EJ, Sahai V, Simeone DM, Zalupski M. A phase I trial of cabozantinib (XL184) and gemcitabine in advanced pancreatic cancer. Journal of Clinical Oncology. 34: 334-334. DOI: 10.1200/Jco.2016.34.4_Suppl.334  0.334
2016 Zhang Y, Velez-Delgado A, Mathew E, Li D, Mendez FM, Flannagan K, Rhim AD, Simeone DM, Beatty GL, Magliano MPd. Abstract A096: Myeloid cells are required for pancreatic carcinogenesis and PD-1/PD-L1 checkpoint activation Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A096  0.431
2016 Schradle KA, Cameron HG, Kumar R, Koeppe E, Leflein E, Moisa C, Demerath M, Stoffel EM, Simeone DM. Abstract A11: Assessment of family cancer history in a pancreatic cancer clinic: A pilot study of a web-based survey Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-A11  0.381
2016 Rivera-Baez L, Lin E, Waghray M, Fouladdel S, Azizi E, Wicha M, Sahai V, Simeone D, Nagrath S. Abstract A10: Biomarker independant microfluidic Labyrinth for the high throughput enrichment and characterization of circulating tumor cells in pancreatic cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-A10  0.496
2016 Cuneo KC, Morgan M, Schipper MJ, Maybaum J, Feng MU, Al-Hawary M, Simeone DM, Olson LD, Sahai V, Zalupski M, Lawrence TS. Abstract CT035: A dose escalation trial of the WEE1 inhibitor AZD1775, gemcitabine, and concurrent radiation in locally advanced pancreatic cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Ct035  0.381
2016 Lin E, Rivera L, Fouladdel S, Yoon HJ, Guthrie S, Weiner J, Deol YS, Keller E, Sahai V, Simeone DM, Burness ML, Azizi E, Wicha MS, Nagrath S. Abstract 3307: Label-free high throughput microfluidic device for the isolation and single cell multiplex gene expression analysis of circulating tumor cells from breast cancer patients Cancer Research. 76: 3307-3307. DOI: 10.1158/1538-7445.Am2016-3307  0.406
2016 Maust JD, Simeone D, Sebolt-Leopold J. Abstract 3018: Cotargeting MEK and CDK4/6 to treat pancreatic adenocarcinoma Cancer Research. 76: 3018-3018. DOI: 10.1158/1538-7445.Am2016-3018  0.434
2015 Palmbos PL, Wang L, Yang H, Wang Y, Leflein J, Ahmet ML, Wilkinson JE, Kumar-Sinha C, Ney G, Tomlins SA, Daignault SD, Kunju LP, Wu XR, Lotan Y, Liebert M, ... ... Simeone DM, et al. ATDC (TRIM29) Drives Invasive Bladder Cancer Formation. Cancer Research. PMID 26471361 DOI: 10.1158/0008-5472.Can-15-0603  0.399
2015 Zhou J, Fang CX, Shen J, Schipper MJ, Zalupski MM, Minter RM, Simeone DM, Hart D, Eagle T, Kimmel GW, Vainshtein J, Lawrence TS, Feng M. Definitive Chemoradiation With Full-dose Gemcitabine for Unresectable Pancreatic Cancer: Efficacy of Involved-Field Radiotherapy. American Journal of Clinical Oncology. PMID 26165418 DOI: 10.1097/Coc.0000000000000200  0.43
2015 Bednar F, Schofield HK, Collins MA, Yan W, Zhang Y, Shyam N, Eberle JA, Almada LL, Olive KP, Bardeesy N, Fernandez-Zapico ME, Nakada D, Simeone DM, Morrison SJ, Pasca di Magliano M. Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism. Carcinogenesis. PMID 25939753 DOI: 10.1093/Carcin/Bgv058  0.464
2015 Chari ST, Kelly K, Hollingsworth MA, Thayer SP, Ahlquist DA, Andersen DK, Batra SK, Brentnall TA, Canto M, Cleeter DF, Firpo MA, Gambhir SS, Go VL, Hines OJ, Kenner BJ, ... ... Simeone DM, et al. Early Detection of Sporadic Pancreatic Cancer: Summative Review. Pancreas. 44: 693-712. PMID 25931254 DOI: 10.1097/Mpa.0000000000000368  0.386
2015 Tan Z, Yin H, Nie S, Lin Z, Zhu J, Ruffin MT, Anderson MA, Simeone DM, Lubman DM. Large-scale identification of core-fucosylated glycopeptide sites in pancreatic cancer serum using mass spectrometry. Journal of Proteome Research. 14: 1968-78. PMID 25732060 DOI: 10.1021/Acs.Jproteome.5B00068  0.435
2015 Wang L, Yang H, Abel EV, Ney GM, Palmbos PL, Bednar F, Zhang Y, Leflein J, Waghray M, Owens S, Wilkinson JE, Prasad J, Ljungman M, Rhim AD, Pasca di Magliano M, ... Simeone DM, et al. ATDC induces an invasive switch in KRAS-induced pancreatic tumorigenesis. Genes & Development. 29: 171-83. PMID 25593307 DOI: 10.1101/Gad.253591.114  0.419
2015 Jiang W, Zhang Y, Kane KT, Collins MA, Simeone DM, di Magliano MP, Nguyen KT. CD44 regulates pancreatic cancer invasion through MT1-MMP. Molecular Cancer Research : McR. 13: 9-15. PMID 25566991 DOI: 10.1158/1541-7786.Mcr-14-0076  0.418
2015 Chen R, Dawson DW, Pan S, Ottenhof NA, de Wilde RF, Wolfgang CL, May DH, Crispin DA, Lai LA, Lay AR, Waghray M, Wang S, McIntosh MW, Simeone DM, Maitra A, et al. Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. 95: 43-55. PMID 25347153 DOI: 10.1038/Labinvest.2014.128  0.456
2015 Waghray M, Grace G, Yalamanchili M, Wang L, Dziubinski M, Zeinali M, Nagrath S, Simeone D. Abstract PR03: Mesenchymal stem cells in pancreatic cancer possess unique properties in promoting tumor growth and metastasis Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-Pr03  0.454
2015 Abel EV, Goto M, Dziubinski ML, Kumar C, Ramanathan N, Simeone DM. Abstract A65: Pancreatic cancer stem cell function is regulated by HNF1A Cancer Research. 75: 2335-2335. DOI: 10.1158/1538-7445.Panca2014-A65  0.412
2015 Zhang Y, Mathew E, Mendez F, Flannagan K, Simeone D, Magliano MPD. Abstract LB-205: Myeloid cells are required to establish an immune-suppressive regulatory network in pancreatic cancer by activating the PD-1/PD-L1 checkpoint Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-205  0.433
2015 Schofield H, Bednar F, Collins M, Yan W, Zhang Y, Shyam N, Eberle J, Olive K, Bardeesy N, Nakada D, Simeone D, Morrison S, Magliano MPd. Abstract LB-061: Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-061  0.431
2015 Zhang Z, Shiratsuchi H, Lin J, Chen G, Reddy RM, Azizi E, Fouladdel S, Chang AC, Lin L, Jiang H, Waghray M, Simeone DM, Wicha MS, Beer DG, Luker G, et al. Abstract 370: Expansion of CTCs from early stage lung cancer patients using a microfluidic co-culture model Cancer Research. 75: 370-370. DOI: 10.1158/1538-7445.Am2015-370  0.39
2015 Pal A, Magliano MPD, Simeone D, Peterson L, Potu H, Talpaz M, Donato N. Abstract 1748: Usp9x as a novel therapeutic target in human pancreatic cancer Cancer Research. 75: 1748-1748. DOI: 10.1158/1538-7445.Am2015-1748  0.449
2015 Zeinali M, Murlidhar V, Fouladdel S, Hafner M, Shao S, Azizi E, Wicha MS, Cuneo K, Simeone DM, Nagrath S. Abstract 1595: Analysis of circulating epithelial and EMT-like CTCs in pancreatic cancer using a sensitive microfluidic CTC capture device Cancer Research. 75: 1595-1595. DOI: 10.1158/1538-7445.Am2015-1595  0.487
2015 Rivera-Baez L, Lin E, Yoon HJ, Waghray M, Fouladdel S, Azizi E, Wicha M, Simeone D, Nagrath S. Abstract 1594: Application of label-free microfluidic technologies for the enrichment, expansion and characterization of circulating tumor cells in pancreatic cancer Cancer Research. 75: 1594-1594. DOI: 10.1158/1538-7445.Am2015-1594  0.49
2015 Lin E, Rivera L, Yoon HJ, Fouladdel S, Wieger J, Guthrie S, Deol YS, Clouthier SG, Luther TK, Simeone DM, Burness ML, Azizi E, Wicha MS, Nagrath S. Abstract 1593: Label-free high throughput microfluidic device for the isolation of circulating tumor cells from breast cancer patients Cancer Research. 75: 1593-1593. DOI: 10.1158/1538-7445.Am2015-1593  0.399
2015 Londoño-Joshi AI, Pratt E, Cowan RW, Samuels ML, Kotsopoulos S, Olson J, Long F, Anderson MA, Simeone D, Rhim AD. Abstract 1572: Sensitive and robust targeted sequencing of pancreatic precancer and tumors using microfluidic single-molecule enrichment Cancer Research. 75: 1572-1572. DOI: 10.1158/1538-7445.Am2015-1572  0.371
2014 Zhang Z, Shiratsuchi H, Lin J, Chen G, Reddy RM, Azizi E, Fouladdel S, Chang AC, Lin L, Jiang H, Waghray M, Luker G, Simeone DM, Wicha MS, Beer DG, et al. Expansion of CTCs from early stage lung cancer patients using a microfluidic co-culture model. Oncotarget. 5: 12383-97. PMID 25474037 DOI: 10.18632/Oncotarget.2592  0.369
2014 Nie S, Yin H, Tan Z, Anderson MA, Ruffin MT, Simeone DM, Lubman DM. Quantitative analysis of single amino acid variant peptides associated with pancreatic cancer in serum by an isobaric labeling quantitative method. Journal of Proteome Research. 13: 6058-66. PMID 25393578 DOI: 10.1021/Pr500934U  0.343
2014 Cuneo KC, Chenevert TL, Ben-Josef E, Feng MU, Greenson JK, Hussain HK, Simeone DM, Schipper MJ, Anderson MA, Zalupski MM, Al-Hawary M, Galban CJ, Rehemtulla A, Feng FY, Lawrence TS, et al. A pilot study of diffusion-weighted MRI in patients undergoing neoadjuvant chemoradiation for pancreatic cancer. Translational Oncology. 7: 644-9. PMID 25389460 DOI: 10.1016/J.Tranon.2014.07.005  0.382
2014 Kim EJ, Sahai V, Abel EV, Griffith KA, Greenson JK, Takebe N, Khan GN, Blau JL, Craig R, Balis UG, Zalupski MM, Simeone DM. Pilot clinical trial of hedgehog pathway inhibitor GDC-0449 (vismodegib) in combination with gemcitabine in patients with metastatic pancreatic adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 5937-45. PMID 25278454 DOI: 10.1158/1078-0432.Ccr-14-1269  0.418
2014 Murlidhar V, Zeinali M, Grabauskiene S, Ghannad-Rezaie M, Wicha MS, Simeone DM, Ramnath N, Reddy RM, Nagrath S. A radial flow microfluidic device for ultra-high-throughput affinity-based isolation of circulating tumor cells Small. 10: 4895-4904. PMID 25074448 DOI: 10.1002/Smll.201400719  0.341
2014 Bednar F, Simeone DM. Recent advances in pancreatic surgery. Current Opinion in Gastroenterology. 30: 518-23. PMID 25010685 DOI: 10.1097/Mog.0000000000000096  0.301
2014 Kanwar SS, Dunlay CJ, Simeone DM, Nagrath S. Microfluidic device (ExoChip) for on-chip isolation, quantification and characterization of circulating exosomes Lab On a Chip. 14: 1891-1900. PMID 24722878 DOI: 10.1039/C4Lc00136B  0.389
2014 Abel EV, Kim EJ, Wu J, Hynes M, Bednar F, Proctor E, Wang L, Dziubinski ML, Simeone DM. The Notch pathway is important in maintaining the cancer stem cell population in pancreatic cancer. Plos One. 9: e91983. PMID 24647545 DOI: 10.1371/Journal.Pone.0091983  0.486
2014 Nie S, Lo A, Wu J, Zhu J, Tan Z, Simeone DM, Anderson MA, Shedden KA, Ruffin MT, Lubman DM. Glycoprotein biomarker panel for pancreatic cancer discovered by quantitative proteomics analysis. Journal of Proteome Research. 13: 1873-84. PMID 24571389 DOI: 10.1021/Pr400967X  0.435
2014 Adler D, Max Schmidt C, Al-Haddad M, Barthel JS, Ljung BM, Merchant NB, Romagnuolo J, Shaaban AM, Simeone D, Bishop Pitman M, Field A, Layfield LJ. Clinical evaluation, imaging studies, indications for cytologic study, and preprocedural requirements for duct brushing studies and pancreatic FNA: the Papanicolaou Society of Cytopathology recommendations for pancreatic and biliary cytology. Diagnostic Cytopathology. 42: 325-32. PMID 24554480 DOI: 10.1002/Dc.23095  0.31
2014 Wang L, Yang H, Palmbos PL, Ney G, Detzler TA, Coleman D, Leflein J, Davis M, Zhang M, Tang W, Hicks JK, Helchowski CM, Prasad J, Lawrence TS, Xu L, ... ... Simeone DM, et al. ATDC/TRIM29 phosphorylation by ATM/MAPKAP kinase 2 mediates radioresistance in pancreatic cancer cells. Cancer Research. 74: 1778-88. PMID 24469230 DOI: 10.1158/0008-5472.Can-13-2289  0.372
2014 Li L, Hao X, Qin J, Tang W, He F, Smith A, Zhang M, Simeone DM, Qiao XT, Chen ZN, Lawrence TS, Xu L. Antibody against CD44s inhibits pancreatic tumor initiation and postradiation recurrence in mice. Gastroenterology. 146: 1108-18. PMID 24397969 DOI: 10.1053/J.Gastro.2013.12.035  0.401
2014 Al-Hawary MM, Francis IR, Chari ST, Fishman EK, Hough DM, Lu DS, Macari M, Megibow AJ, Miller FH, Mortele KJ, Merchant NB, Minter RM, Tamm EP, Sahani DV, Simeone DM. Pancreatic ductal adenocarcinoma radiology reporting template: consensus statement of the society of abdominal radiology and the american pancreatic association. Gastroenterology. 146: 291-304.e1. PMID 24355035 DOI: 10.1053/J.Gastro.2013.11.004  0.364
2014 Al-Hawary MM, Francis IR, Chari ST, Fishman EK, Hough DM, Lu DS, Macari M, Megibow AJ, Miller FH, Mortele KJ, Merchant NB, Minter RM, Tamm EP, Sahani DV, Simeone DM. Pancreatic ductal adenocarcinoma radiology reporting template: consensus statement of the Society of Abdominal Radiology and the American Pancreatic Association. Radiology. 270: 248-60. PMID 24354378 DOI: 10.1148/Radiol.13131184  0.364
2014 Michaud NR, Wang Y, McEachern KA, Jordan JJ, Mazzola AM, Hernandez A, Jalla S, Chesebrough JW, Hynes MJ, Belmonte MA, Wang L, Kang JS, Jovanovic J, Laing N, Jenkins DW, ... ... Simeone DM, et al. Novel neutralizing hedgehog antibody MEDI-5304 exhibits antitumor activity by inhibiting paracrine hedgehog signaling. Molecular Cancer Therapeutics. 13: 386-98. PMID 24344235 DOI: 10.1158/1535-7163.Mct-13-0420  0.397
2014 Lin Z, Yin H, Lo A, Ruffin MT, Anderson MA, Simeone DM, Lubman DM. Label-free relative quantification of alpha-2-macroglobulin site-specific core-fucosylation in pancreatic cancer by LC-MS/MS. Electrophoresis. 35: 2108-15. PMID 24285556 DOI: 10.1002/Elps.201300376  0.357
2014 Palmbos P, Wang L, Yang H, LeFlein J, Wilkinson JE, Kumar-Sinha C, Kunju LP, Daignault S, Wu X, Lotan Y, Liebert M, Ljungman M, Simeone D. Abstract B24: ATDC (Trim29) drives invasive bladder cancer formation Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-B24  0.431
2014 Kanwar SS, Dunlay CJ, Simeone DM, Nagrath S. Abstract 5591: Simultaneous isolation and quantification of circulating exosomes for cancer biomarker discovery Cancer Research. 74: 5591-5591. DOI: 10.1158/1538-7445.Am2014-5591  0.428
2014 Pal A, Magliano MPd, Talpaz M, Dziubinski M, Simeone D, Donato NJ. Abstract 4434: Role of Deubiquitinase Usp9x in pancreatic cancers: Tumor promoter or tumor suppressor Cancer Research. 74: 4434-4434. DOI: 10.1158/1538-7445.Am2014-4434  0.468
2014 Jack RM, Grafton MM, Cieslak RA, Jue DC, Griffith C, Rodrigues D, Nagrath S, Simeone D. Abstract 3477: Continuous isolation, labeling and collection of viable CTCs using an integrated microfluidic device Cancer Research. 74: 3477-3477. DOI: 10.1158/1538-7445.Am2014-3477  0.401
2014 Zhang JZ, Shiratsuchi H, Lin J, Chen G, Reddy RM, Azizi E, Fouladdel S, Chang AC, Lin L, Simeone DM, Wicha MS, Beer DG, Ramnath N, Nagrath S. Abstract 3075:Ex-vivoexpansion of circulating tumor cells in early lung cancer using a microfluidic model Cancer Research. 74: 3075-3075. DOI: 10.1158/1538-7445.Am2014-3075  0.427
2014 Murlidhar V, Reddy RM, Zeinali M, Grabauskiene S, Ghannad-Rezaie M, Wicha MS, Simeone DM, Ramnath N, Nagrath S. Abstract 3069: Radial flow microfluidic device for high-throughput affinity-based isolation of circulating tumor cells Cancer Research. 74: 3069-3069. DOI: 10.1158/1538-7445.Am2014-3069  0.399
2014 Chen R, Pan S, Maitra A, Simeone D, Dawson D, Brentnall T. Abstract 2866: Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma Cancer Research. 74: 2866-2866. DOI: 10.1158/1538-7445.Am2014-2866  0.422
2014 Lee SY, Lloyd WR, Wilson RH, Chandra M, McKenna B, Simeone D, Scheiman J, Mycek MA. Photon-tissue interaction model for quantitative assessment of biological tissues Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8935. DOI: 10.1117/12.2046980  0.302
2014 Scheiman J, Wilson RH, Chandra M, Simeone DM, Taylor J, Lee OE, Lloyd WR, Lee SY, Mycek M. Mo1164 Optical Spectroscopy Distinguishes Pancreatic Cancer From Non-Malignant Pancreatic Tissues Gastroenterology. 146: S-574. DOI: 10.1016/S0016-5085(14)62080-1  0.421
2013 Lloyd WR, Wilson RH, Lee SY, Chandra M, McKenna B, Simeone D, Scheiman J, Mycek MA. In vivo optical spectroscopy for improved detection of pancreatic adenocarcinoma: a feasibility study. Biomedical Optics Express. 5: 9-15. PMID 24466472 DOI: 10.1364/Boe.5.000009  0.372
2013 Lee SY, Lloyd WR, Chandra M, Wilson RH, McKenna B, Simeone D, Scheiman J, Mycek MA. Characterizing human pancreatic cancer precursor using quantitative tissue optical spectroscopy. Biomedical Optics Express. 4: 2828-34. PMID 24409383 DOI: 10.1364/Boe.4.002828  0.341
2013 Liddle RA, Freeman M, Simeone DM, Saluja AK, Castillo CF, Maitra A, Pandol SJ, Go VL. Minutes of the business meeting of the American Pancreatic Association, Friday, November 2, 2012, Miami, Florida. Pancreas. 42: 1333-4. PMID 24152959 DOI: 10.1097/Mpa.0B013E3182A99936  0.316
2013 Li L, Tang W, Wu X, Karnak D, Meng X, Thompson R, Hao X, Li Y, Qiao XT, Lin J, Fuchs J, Simeone DM, Chen ZN, Lawrence TS, Xu L. HAb18G/CD147 promotes pSTAT3-mediated pancreatic cancer development via CD44s. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 6703-15. PMID 24132924 DOI: 10.1158/1078-0432.Ccr-13-0621  0.337
2013 Yoon HJ, Kim TH, Zhang Z, Azizi E, Pham TM, Paoletti C, Lin J, Ramnath N, Wicha MS, Hayes DF, Simeone DM, Nagrath S. Sensitive capture of circulating tumour cells by functionalized graphene oxide nanosheets. Nature Nanotechnology. 8: 735-41. PMID 24077027 DOI: 10.1038/Nnano.2013.194  0.36
2013 Bednar F, Scheiman JM, McKenna BJ, Simeone DM. Breast cancer metastases to the pancreas. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 17: 1826-31. PMID 23918083 DOI: 10.1007/S11605-013-2291-5  0.33
2013 Waghray M, Yalamanchili M, di Magliano MP, Simeone DM. Deciphering the role of stroma in pancreatic cancer. Current Opinion in Gastroenterology. 29: 537-43. PMID 23892539 DOI: 10.1097/Mog.0B013E328363Affe  0.447
2013 Zhang Y, Morris JP, Yan W, Schofield HK, Gurney A, Simeone DM, Millar SE, Hoey T, Hebrok M, Pasca di Magliano M. Canonical wnt signaling is required for pancreatic carcinogenesis. Cancer Research. 73: 4909-22. PMID 23761328 DOI: 10.1158/0008-5472.Can-12-4384  0.42
2013 Kim EJ, Ben-Josef E, Herman JM, Bekaii-Saab T, Dawson LA, Griffith KA, Francis IR, Greenson JK, Simeone DM, Lawrence TS, Laheru D, Wolfgang CL, Williams T, Bloomston M, Moore MJ, et al. A multi-institutional phase 2 study of neoadjuvant gemcitabine and oxaliplatin with radiation therapy in patients with pancreatic cancer. Cancer. 119: 2692-700. PMID 23720019 DOI: 10.1002/Cncr.28117  0.382
2013 Abel EV, Simeone DM. Biology and clinical applications of pancreatic cancer stem cells Gastroenterology. 144: 1241-1248. PMID 23622133 DOI: 10.1053/J.Gastro.2013.01.072  0.464
2013 Proctor E, Waghray M, Lee CJ, Heidt DG, Yalamanchili M, Li C, Bednar F, Simeone DM. Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma. Plos One. 8: e55820. PMID 23437065 DOI: 10.1371/Journal.Pone.0055820  0.443
2013 Kothari V, Wei I, Shankar S, Kalyana-Sundaram S, Wang L, Ma LW, Vats P, Grasso CS, Robinson DR, Wu YM, Cao X, Simeone DM, Chinnaiyan AM, Kumar-Sinha C. Outlier kinase expression by RNA sequencing as targets for precision therapy. Cancer Discovery. 3: 280-93. PMID 23384775 DOI: 10.1158/2159-8290.Cd-12-0336  0.4
2013 Yoon HJ, Kim TH, Zhang Z, Ramnath N, Wicha MS, Hayes DF, Simeone DM, Nagrath S. Abstract 5109: Integrated micro nanotechnology for the sensitive isolation of circulating tumor cells. Cancer Research. 73: 5109-5109. DOI: 10.1158/1538-7445.Am2013-5109  0.421
2013 Kumar-Sinha C, Kothari V, Wei I, Shankar S, Kalyana-Sundaram S, Wang L, Ma LW, Vats P, Grasso C, Robinson D, Wu Y, Cao X, Simeone DM, Chinnaiyan AM. Abstract 3136: Sample specific outlier kinase expression identified by RNA-Seq provide targets for precision therapy. Cancer Research. 73: 3136-3136. DOI: 10.1158/1538-7445.Am2013-3136  0.372
2013 Palmbos P, Wang L, Yang H, Detzler T, Ney G, Hart J, Daignault-Newton S, Kunju LP, Kumar-Sinha C, Liebert M, Ljungman M, Simeone D. Abstract 313: ATDC drives bladder cancer formation by promoting methylation of the PTEN promoter and inhibition of p53 function. Cancer Research. 73: 313-313. DOI: 10.1158/1538-7445.Am2013-313  0.42
2013 Grafton MM, Jack RM, Cieslak R, Rodriguez D, Sharma S, Simeone DM, Nagrath S. Abstract 1457: An integrated microfluidic device for circulating tumor cell detection in pancreatic cancer patients. Cancer Research. 73: 1457-1457. DOI: 10.1158/1538-7445.Am2013-1457  0.482
2013 Kothari V, Iris W, Shankar S, Kalyana-Sundaram S, Wang L, Ma LW, Vats P, Grasso CS, Robinson DR, Wu Y, Cao X, Simeone DM, Chinnaiyan AM, Kumar-Sinha C. Abstract PR16: Targeting cancer-specific kinase dependency for precision therapy Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-Pr16  0.404
2013 Bednar F, Collins MA, Yan W, Zhang Y, Nakada D, Simeone DM, Morrison SJ, Pasca di Magliano M. Bmi1 is required for murine pancreatic cancer initiation Journal of the American College of Surgeons. 217: S133. DOI: 10.1016/J.Jamcollsurg.2013.07.309  0.388
2012 Palmbos PL, Wang L, Yang H, Detzler T, Ney G, Lotan Y, Wilkerson JE, Kunju P, Ljungman M, Liebert M, Simeone DM. ATDC as a novel oncogene in bladder cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 269. PMID 27968252 DOI: 10.1200/Jco.2012.30.5_Suppl.269  0.452
2012 Yen WC, Fischer MM, Hynes M, Wu J, Kim E, Beviglia L, Yeung VP, Song X, Kapoun AM, Lewicki J, Gurney A, Simeone DM, Hoey T. Anti-DLL4 has broad spectrum activity in pancreatic cancer dependent on targeting DLL4-Notch signaling in both tumor and vasculature cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 5374-86. PMID 22952347 DOI: 10.1158/1078-0432.Ccr-12-0736  0.414
2012 Venkatesha VA, Parsels LA, Parsels JD, Zhao L, Zabludoff SD, Simeone DM, Maybaum J, Lawrence TS, Morgan MA. Sensitization of pancreatic cancer stem cells to gemcitabine by Chk1 inhibition. Neoplasia (New York, N.Y.). 14: 519-25. PMID 22787433 DOI: 10.1593/Neo.12538  0.461
2012 Kumar-Sinha C, Wei I, Simeone DM. Emerging frontiers in pancreatic cancer research: Elaboration of key genes, cells and the extracellular milieu Current Opinion in Gastroenterology. 28: 516-522. PMID 22759592 DOI: 10.1097/Mog.0B013E3283567F69  0.473
2012 El-Zaatari M, Daignault S, Tessier A, Kelsey G, Travnikar LA, Cantu EF, Lee J, Plonka CM, Simeone DM, Anderson MA, Merchant JL. Plasma Shh levels reduced in pancreatic cancer patients. Pancreas. 41: 1019-28. PMID 22513293 DOI: 10.1097/Mpa.0B013E31824A0Eeb  0.429
2012 Partyka K, McDonald M, Maupin KA, Brand R, Kwon R, Simeone DM, Allen P, Haab BB. Comparison of surgical and endoscopic sample collection for pancreatic cyst fluid biomarker identification. Journal of Proteome Research. 11: 2904-11. PMID 22439797 DOI: 10.1021/Pr2012736  0.311
2012 Bednar F, Simeone DM. Metformin and cancer stem cells: old drug, new targets. Cancer Prevention Research (Philadelphia, Pa.). 5: 351-4. PMID 22389436 DOI: 10.1158/1940-6207.Capr-12-0026  0.392
2012 Zhu J, He J, Liu Y, Simeone DM, Lubman DM. Identification of glycoprotein markers for pancreatic cancer CD24+CD44+ stem-like cells using nano-LC-MS/MS and tissue microarray. Journal of Proteome Research. 11: 2272-81. PMID 22335271 DOI: 10.1021/Pr201059G  0.372
2012 Minter RM, Simeone DM. Contemporary management of nonfunctioning pancreatic neuroendocrine tumors. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 16: 435-46. PMID 22009463 DOI: 10.1007/S11605-011-1693-5  0.328
2012 Palmbos PL, Wang L, Yang H, Detzler T, Ney G, Lotan Y, Healy PN, Daignault-Newton S, Kunju P, Kumar C, Ljungman M, Liebert M, Simeone DM. Novel oncogenic function of ATDC in bladder cancer. Journal of Clinical Oncology. 30: 4591-4591. DOI: 10.1200/Jco.2012.30.15_Suppl.4591  0.417
2012 Bednar F, Zhang Y, Nakada D, Simeone DM, Morrison SJ, Magliano MPd. Abstract B59: Bmi1 is required for murine pancreatic cancer initiation. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-B59  0.438
2012 Wang L, Yang H, Bednar F, Zhang Y, Leflein J, Detzler T, Ney GM, Magliano MPd, Simeone DM. Abstract B49: ATDC synergizes with oncogenic Kras to induce invasive pancreatic adeno-carcinoma in transgenic mice. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-B49  0.369
2012 Wang L, Lawrence T, Xu L, Canman C, Ljungman M, Simeone D, Yang H, Palmbos P, Ney G, Detzler TA, Coleman D, Davis M, Hicks K, Helchowski CM. Abstract A93: Radiation-induced phosphorylation of ATDC via ATM/MAPKAP kinase 2 signaling mediates radioresistance of pancreatic cancer cells. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A93  0.408
2012 Kim EJ, Khan GN, Griffith K, Greenson J, Takebe N, Zalupski M, Simeone D. Abstract A40: Cancer stem cells (CSC) and inhibition of hedgehog (Hh) pathway signaling in advanced pancreatic cancer: GDC-0449 in combination with gemcitabine (Gem). Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A40  0.474
2012 Wei I, Kothari V, Shankar S, Kalyana-Sundaram S, Grasso C, Robinson D, Cao X, Simeone D, Chinnaiyan A, Kumar-Sinha C. Abstract A17: Inhibiting polo-like kinases for the treatment of pancreatic cancer: Targeting kinase outliers for personalized therapy. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A17  0.45
2012 Maupin K, Curnutte B, Cao Z, Partyka K, McDonald M, Kwon R, Allen P, Brand R, Simeone D, Haab BB. Abstract 4555: Protein and glycan biomarkers of malignant potential in pancreatic cyst fluid Cancer Research. 72: 4555-4555. DOI: 10.1158/1538-7445.Am2012-4555  0.441
2012 Simeone DM, Liddle RA, Chari ST, Saluja AK, Freeman M, Maitra A, Pandol SJ, Go VLW. Minutes of the Business Meeting of the American Pancreatic Association, Friday, November 4, 2011, Chicago, Illinois Pancreas. 41: 1343. DOI: 10.1097/Mpa.0B013E31827083F1  0.316
2011 Yue T, Maupin KA, Fallon B, Li L, Partyka K, Anderson MA, Brenner DE, Kaul K, Zeh H, Moser AJ, Simeone DM, Feng Z, Brand RE, Haab BB. Enhanced discrimination of malignant from benign pancreatic disease by measuring the CA 19-9 antigen on specific protein carriers. Plos One. 6: e29180. PMID 22220206 DOI: 10.1371/Journal.Pone.0029180  0.313
2011 Kwon RS, Simeone DM. The Use of Protein-Based Biomarkers for the Diagnosis of Cystic Tumors of the Pancreas International Journal of Proteomics. 2011: 413646-413646. PMID 22110950 DOI: 10.1155/2011/413646  0.337
2011 Bednar F, Simeone DM. Pancreatic cancer stem cell biology and its therapeutic implications. Journal of Gastroenterology. 46: 1345-52. PMID 22048257 DOI: 10.1007/S00535-011-0494-7  0.487
2011 Simeone DM. 2011 American Pancreatic Association presidential address: demystifying the pancreas. Pancreas. 40: 1163-1164. PMID 22001829 DOI: 10.1097/Mpa.0B013E3182346Cfb  0.345
2011 Li C, Wu JJ, Hynes M, Dosch J, Sarkar B, Welling TH, Pasca di Magliano M, Simeone DM. c-Met is a marker of pancreatic cancer stem cells and therapeutic target. Gastroenterology. 141: 2218-2227.e5. PMID 21864475 DOI: 10.1053/J.Gastro.2011.08.009  0.419
2011 Kim EJ, Simeone DM. Advances in pancreatic cancer. Current Opinion in Gastroenterology. 27: 460-466. PMID 21778878 DOI: 10.1097/Mog.0B013E328349E31F  0.474
2011 Li C, Zolotarevsky E, Thompson I, Anderson MA, Simeone DM, Casper JM, Mullenix MC, Lubman DM. A multiplexed bead assay for profiling glycosylation patterns on serum protein biomarkers of pancreatic cancer. Electrophoresis. 32: 2028-35. PMID 21732554 DOI: 10.1002/Elps.201000693  0.41
2011 Parsels LA, Qian Y, Tanska DM, Gross M, Zhao L, Hassan MC, Arumugarajah S, Parsels JD, Hylander-Gans L, Simeone DM, Morosini D, Brown JL, Zabludoff SD, Maybaum J, Lawrence TS, et al. Assessment of chk1 phosphorylation as a pharmacodynamic biomarker of chk1 inhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3706-15. PMID 21482692 DOI: 10.1158/1078-0432.Ccr-10-3082  0.459
2011 Lin Z, Simeone DM, Anderson MA, Brand RE, Xie X, Shedden KA, Ruffin MT, Lubman DM. Mass spectrometric assay for analysis of haptoglobin fucosylation in pancreatic cancer. Journal of Proteome Research. 10: 2602-11. PMID 21417406 DOI: 10.1021/Pr200102H  0.445
2011 Yue T, Maupin K, Partyka K, Li L, Anderson MA, Brenner D, Simeone D, Feng Z, Brand RE, Haab BB. Abstract 2216: Enhanced discrimination of malignant from benign pancreatic disease by measuring the CA 19-9 antigen on specific protein carriers Cancer Research. 71: 2216-2216. DOI: 10.1158/1538-7445.Am2011-2216  0.326
2011 Wilson RH, Chandra M, Lloyd W, Chen LC, Scheiman J, Simeone D, McKenna B, Mycek MA. Optical spectroscopy for quantitative sensing in human pancreatic tissues Optics Infobase Conference Papers. DOI: 10.1117/12.889724  0.356
2011 Chari ST, Simeone DM, Warshaw AL, Saluja AK, Freeman M, Liddle RA, Pandol SJ, Go VLW. Minutes of the Business Meeting of the American Pancreatic Association Friday, November 5, 2010, Chicago, Illinois Pancreas. 40: 1307. DOI: 10.1097/Mpa.0B013E3182334Ed9  0.316
2011 Proctor EN, Wu J, Hynes MJ, Dosch J, Simeone DM. Inhibition Of The Notch Signaling Pathway Targets Cancer Stem Cells In Pancreatic Ductal Adenocarcinoma Journal of Surgical Research. 165: 303. DOI: 10.1016/J.Jss.2010.11.354  0.409
2011 Ben-Josef E, Schipper M, Francis I, Khan G, Hadley S, Lawrence T, Simeone D, Abrams R, Sonnenday C, Zalupski M. Phase I/II Radiation Dose-Escalation Trial of Intensity Modulated Radiotherapy (IMRT) with Concurrent Fixed Dose-Rate Gemcitabine (FDR-G) for Unresectable Pancreatic Cancer International Journal of Radiation Oncology*Biology*Physics. 81: S127-S128. DOI: 10.1016/J.Ijrobp.2011.06.263  0.3
2010 Li C, Kim HY, Vuong H, Patwa T, Pal M, Brand RE, Simeone DM, Lubman DM. The identification of auto-antibodies in pancreatic cancer patient sera using a naturally fractionated Panc-1 cell line. Cancer Biomarkers : Section a of Disease Markers. 7: 25-37. PMID 21045262 DOI: 10.3233/Cbm-2010-0145  0.464
2010 Wilson RH, Chandra M, Chen LC, Lloyd WR, Scheiman J, Simeone D, Purdy J, McKenna B, Mycek MA. Photon-tissue interaction model enables quantitative optical analysis of human pancreatic tissues. Optics Express. 18: 21612-21. PMID 20941059 DOI: 10.1364/Oe.18.021612  0.317
2010 Anderson MA, Brenner DE, Scheiman JM, Simeone DM, Singh N, Sikora MJ, Zhao L, Mertens AN, Rae JM. Reliable gene expression measurements from fine needle aspirates of pancreatic tumors: effect of amplicon length and quality assessment. The Journal of Molecular Diagnostics : Jmd. 12: 566-75. PMID 20709792 DOI: 10.2353/Jmoldx.2010.090107  0.361
2010 Lee CJ, Spalding AC, Ben-Josef E, Wang L, Simeone DM. In vivo bioluminescent imaging of irradiated orthotopic pancreatic cancer xenografts in nonobese diabetic-severe combined immunodeficient mice: a novel method for targeting and assaying efficacy of ionizing radiation. Translational Oncology. 3: 153-9. PMID 20563256 DOI: 10.1593/Tlo.09184  0.404
2010 Morgan MA, Parsels LA, Zhao L, Parsels JD, Davis MA, Hassan MC, Arumugarajah S, Hylander-Gans L, Morosini D, Simeone DM, Canman CE, Normolle DP, Zabludoff SD, Maybaum J, Lawrence TS. Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair. Cancer Research. 70: 4972-81. PMID 20501833 DOI: 10.1158/0008-5472.Can-09-3573  0.326
2010 Dai L, Li C, Shedden KA, Lee CJ, Li C, Quoc H, Simeone DM, Lubman DM. Quantitative proteomic profiling studies of pancreatic cancer stem cells. Journal of Proteome Research. 9: 3394-402. PMID 20486718 DOI: 10.1021/Pr100231M  0.448
2010 Dosch JS, Pasca di Magliano M, Simeone DM. Pancreatic cancer and hedgehog pathway signaling: new insights. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. 10: 151-7. PMID 20453550 DOI: 10.1159/000225923  0.398
2010 Haab BB, Porter A, Yue T, Li L, Scheiman J, Anderson MA, Barnes D, Schmidt CM, Feng Z, Simeone DM. Glycosylation variants of mucins and CEACAMs as candidate biomarkers for the diagnosis of pancreatic cystic neoplasms. Annals of Surgery. 251: 937-45. PMID 20395854 DOI: 10.1097/Sla.0B013E3181D7738D  0.366
2010 Chandra M, Scheiman J, Simeone D, McKenna B, Purdy J, Mycek MA. Spectral areas and ratios classifier algorithm for pancreatic tissue classification using optical spectroscopy. Journal of Biomedical Optics. 15: 010514. PMID 20210425 DOI: 10.1117/1.3314900  0.355
2010 Khan GN, di Magliano MP, Simeone DM. New Frontiers in Pancreatic Cancer Research Surgical Oncology Clinics of North America. 19: 431-451. PMID 20159524 DOI: 10.1016/J.Soc.2009.11.010  0.414
2010 Patwa T, Li C, Simeone DM, Lubman DM. Glycoprotein analysis using protein microarrays and mass spectrometry. Mass Spectrometry Reviews. 29: 830-44. PMID 20077480 DOI: 10.1002/Mas.20269  0.326
2010 Pausawasdi N, Heidt D, Kwon R, Simeone D, Scheiman J. Long-term follow-up of patients with incidentally discovered pancreatic cystic neoplasms evaluated by endoscopic ultrasound Surgery. 147: 13-20. PMID 19767045 DOI: 10.1016/J.Surg.2009.05.014  0.342
2010 Wilson RH, Chandra M, Lloyd W, Scheiman J, Simeone D, Purdy J, McKenna B, Mycek M. Quantitative optical spectroscopy for pancreatic cancer detection Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2010.Bwb6  0.361
2010 Li C, Hynes M, Dosch J, Wu J, Sarkar B, Magliano MPd, Simeone DM. Abstract LB-257: c-Met: a new cancer stem cell marker and therapeutic target for pancreatic cancer Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-257  0.451
2010 Parsels LA, Morgan MA, Tanska DM, Parsels JD, Davis MA, Hassan MC, Arumugarajah S, Hylander-Gans L, Morosini D, Zhao L, Simeone DM, Canman CE, Normolle DP, Zabludoff SD, Lawrence TS, et al. Abstract 1765: Preclinical optimization of the Chk1/2 inhibitor AZD7762 in combination with gemcitabine in pancreatic cancer Cancer Research. 70: 1765-1765. DOI: 10.1158/1538-7445.Am10-1765  0.484
2010 Warshaw AL, Chari ST, Logsdon CD, Saluja AK, Freeman M, Liddle RA, Simeone DM, Go VLW. Minutes of the Business Meeting of the American Pancreatic Association, Friday, November 6, 2009, Honolulu, Hawaii Pancreas. 39: 1305. DOI: 10.1097/Mpa.0B013E3181F7064D  0.317
2009 Wilson RH, Chandra M, Scheiman J, Simeone D, McKenna B, Purdy J, Mycek MA. Optical spectroscopy detects histological hallmarks of pancreatic cancer. Optics Express. 17: 17502-16. PMID 19907534 DOI: 10.1364/Oe.17.017502  0.358
2009 Philip PA, Mooney M, Jaffe D, Eckhardt G, Moore M, Meropol N, Emens L, O'Reilly E, Korc M, Ellis L, Benedetti J, Rothenberg M, Willett C, Tempero M, Lowy A, ... ... Simeone D, et al. Consensus report of the national cancer institute clinical trials planning meeting on pancreas cancer treatment. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 5660-9. PMID 19858397 DOI: 10.1200/Jco.2009.21.9022  0.436
2009 Patwa TH, Li C, Poisson LM, Kim HY, Pal M, Ghosh D, Simeone DM, Lubman DM. The identification of phosphoglycerate kinase-1 and histone H4 autoantibodies in pancreatic cancer patient serum using a natural protein microarray. Electrophoresis. 30: 2215-26. PMID 19582723 DOI: 10.1002/Elps.200800857  0.457
2009 Li C, Lee CJ, Simeone DM. Identification of human pancreatic cancer stem cells. Methods of Molecular Biology. 568: 161-173. PMID 19582426 DOI: 10.1007/978-1-59745-280-9_10  0.48
2009 Brand RE, Greer JB, Zolotarevsky E, Brand R, Du H, Simeone D, Zisman A, Gorchow A, Lee SC, Roy HK, Anderson MA. Pancreatic Cancer Patients Who Smoke and Drink Are Diagnosed at Younger Ages Clinical Gastroenterology and Hepatology. 7: 1007-1012. PMID 19560558 DOI: 10.1016/J.Cgh.2009.06.008  0.308
2009 Sarkar B, Dosch J, Simeone DM. Cancer Stem Cells: A New Theory Regarding a Timeless Disease Chemical Reviews. 109: 3200-3208. PMID 19522504 DOI: 10.1021/Cr9000397  0.342
2009 Kryczek I, Banerjee M, Cheng P, Vatan L, Szeliga W, Wei S, Huang E, Finlayson E, Simeone D, Welling TH, Chang A, Coukos G, Liu R, Zou W. Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. Blood. 114: 1141-9. PMID 19470694 DOI: 10.1182/Blood-2009-03-208249  0.341
2009 Desai S, Ben-Josef E, Griffith KA, Simeone D, Greenson JK, Francis IR, Hampton J, Colletti L, Chang AE, Lawrence TS, Zalupski MM. Gemcitabine-based combination chemotherapy followed by radiation with capecitabine as adjuvant therapy for resected pancreas cancer. International Journal of Radiation Oncology, Biology, Physics. 75: 1450-5. PMID 19409732 DOI: 10.1016/J.Ijrobp.2009.01.023  0.31
2009 Kryczek I, Liu R, Wang G, Wu K, Shu X, Szeliga W, Vatan L, Finlayson E, Huang E, Simeone D, Redman B, Welling TH, Chang A, Zou W. FOXP3 defines regulatory T cells in human tumor and autoimmune disease. Cancer Research. 69: 3995-4000. PMID 19383912 DOI: 10.1158/0008-5472.Can-08-3804  0.316
2009 Bednar F, Simeone DM. Pancreatic cancer stem cells and relevance to cancer treatments. Journal of Cellular Biochemistry. 107: 40-5. PMID 19301275 DOI: 10.1002/Jcb.22093  0.471
2009 Wang L, Heidt DG, Lee CJ, Yang H, Logsdon CD, Zhang L, Fearon ER, Ljungman M, Simeone DM. Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and beta-catenin stabilization. Cancer Cell. 15: 207-19. PMID 19249679 DOI: 10.1016/J.Ccr.2009.01.018  0.462
2009 Li C, Simeone DM, Brenner DE, Anderson MA, Shedden KA, Ruffin MT, Lubman DM. Pancreatic cancer serum detection using a lectin/glyco-antibody array method. Journal of Proteome Research. 8: 483-92. PMID 19072160 DOI: 10.1021/Pr8007013  0.411
2009 Logsdon CD, Warshaw AL, Forsmark CE, Saluja AK, Chari ST, Liddle RA, Simeone DM, Go VLW. Minutes of the Business Meeting of the American Pancreatic Association Thursday, November 6, 2008, Chicago, Illinois Pancreas. 38: 979. DOI: 10.1097/Mpa.0B013E3181Bd176B  0.316
2009 Lee C, Dosch J, Wang L, Ljungman M, Simeone D. PL4. Expression of ATDC in Pancreatic Cancer Stem Cells Confers Resistance to DNA Damage Journal of Surgical Research. 151: 227. DOI: 10.1016/J.Jss.2008.11.135  0.393
2008 Simeone DM. Pancreatic Cancer Stem Cells: Implications for the Treatment of Pancreatic Cancer Clinical Cancer Research. 14: 5646-5648. PMID 18794070 DOI: 10.1158/1078-0432.Ccr-08-0584  0.489
2008 Grote T, Siwak DR, Fritsche HA, Joy C, Mills GB, Simeone D, Whitcomb DC, Logsdon CD. Validation of reverse phase protein array for practical screening of potential biomarkers in serum and plasma: Accurate detection of CA19-9 levels in pancreatic cancer Proteomics. 8: 3051-3060. PMID 18615426 DOI: 10.1002/Pmic.200700951  0.302
2008 Lee CJ, Li C, Simeone DM. Human pancreatic cancer stem cells: implications for how we treat pancreatic cancer. Translational Oncology. 1: 14-18. PMID 18607507 DOI: 10.1593/Tlo.08013  0.489
2008 Lee CJ, Dosch J, Simeone DM. Pancreatic Cancer Stem Cells Journal of Clinical Oncology. 26: 2806-2812. PMID 18539958 DOI: 10.1200/Jco.2008.16.6702  0.478
2008 Patwa TH, Wang Y, Simeone DM, Lubman DM. Enhanced detection of autoantibodies on protein microarrays using a modified protein digestion technique. Journal of Proteome Research. 7: 2553-61. PMID 18452326 DOI: 10.1021/Pr800023G  0.355
2008 Simeone DM. SSAT/AGA/ASGE state of the art conference on cystic neoplasms of the pancreas. Journal of Gastrointestinal Surgery. 12: 1475-1477. PMID 18224378 DOI: 10.1007/S11605-007-0351-4  0.311
2008 Lee CJ, Scheiman J, Anderson MA, Hines OJ, Reber HA, Farrell J, Kochman ML, Foley PJ, Drebin J, Oh YS, Ginsberg G, Ahmad N, Merchant NB, Isbell J, Parikh AA, ... ... Simeone DM, et al. Risk of malignancy in resected cystic tumors of the pancreas < or =3 cm in size: is it safe to observe asymptomatic patients? A multi-institutional report. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 12: 234-42. PMID 18040749 DOI: 10.1007/S11605-007-0381-Y  0.356
2008 Wilson RH, Chandra M, Scheiman J, Heidt D, Simeone D, McKenna B, Mycek M. Modeling Reflectance and Fluorescence Spectra of Human Pancreatic Tissues for Cancer Diagnostics Frontiers in Optics. DOI: 10.1364/Fio.2008.Ftuk5  0.385
2008 Urrutia RA, Logsdon CD, Forsmark CE, Saluja AK, Chari ST, Simeone DM, Warshaw AL, Go VLW. Minutes of the Business Meeting of the American Pancreatic Association Friday, November 2, 2007, Chicago, Illinois Pancreas. 37: 454-455. DOI: 10.1097/Mpa.0B013E31818De01F  0.316
2008 Haab BB, Porter A, Schmidt M, Lee CJ, Barnes D, Simeone D. GLYCOSYLATION VARIANTS ON MUCINS AS CANDIDATE MARKERS FOR THE DIAGNOSIS OF PANCREATIC CYSTIC NEOPLASMS Pancreas. 37: 472-473. DOI: 10.1097/01.Mpa.0000335466.30936.C1  0.353
2008 Barnes D, Wang L, Ljungman M, Simeone D. 203. ATDC, A Novel DNA Damage Response Protein, Is Highly Expressed in Pancreatic Cancer Journal of Surgical Research. 144: 267-268. DOI: 10.1016/J.Jss.2007.12.231  0.388
2008 Lee CJ, Simeone DM, Lee C, Zielske S, Dosch J, Ljungman M. 140. Pancreatic Cancer Stem Cells are Resistant to Ionizing Radiation and the Chemotherapeutic Agent Gemcitabine Journal of Surgical Research. 144: 238. DOI: 10.1016/J.Jss.2007.12.159  0.397
2007 Chandra M, Scheiman J, Heidt D, Simeone D, McKenna B, Mycek MA. Probing pancreatic disease using tissue optical spectroscopy. Journal of Biomedical Optics. 12: 060501. PMID 18163796 DOI: 10.1117/1.2818029  0.401
2007 Misek DE, Patwa TH, Lubman DM, Simeone DM. Early detection and biomarkers in pancreatic cancer. Journal of the National Comprehensive Cancer Network : Jnccn. 5: 1034-41. PMID 18053427 DOI: 10.6004/Jnccn.2007.0086  0.442
2007 Desai SP, Ben-Josef E, Normolle DP, Francis IR, Greenson JK, Simeone DM, Chang AE, Colletti LM, Lawrence TS, Zalupski MM. Phase I study of oxaliplatin, full-dose gemcitabine, and concurrent radiation therapy in pancreatic cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 4587-92. PMID 17925553 DOI: 10.1200/Jco.2007.12.0592  0.326
2007 Dalerba P, Dylla SJ, Park IK, Liu R, Wang X, Cho RW, Hoey T, Gurney A, Huang EH, Simeone DM, Shelton AA, Parmiani G, Castelli C, Clarke MF. Phenotypic characterization of human colorectal cancer stem cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 10158-63. PMID 17548814 DOI: 10.1073/Pnas.0703478104  0.428
2007 Simeone DM, Ji B, Banerjee M, Arumugam T, Li D, Anderson MA, Bamberger AM, Greenson J, Brand RE, Ramachandran V, Logsdon CD. CEACAM1, a novel serum biomarker for pancreatic cancer. Pancreas. 34: 436-43. PMID 17446843 DOI: 10.1097/Mpa.0B013E3180333Ae3  0.441
2007 Chen J, Anderson M, Misek DE, Simeone DM, Lubman DM. Characterization of apolipoprotein and apolipoprotein precursors in pancreatic cancer serum samples via two-dimensional liquid chromatography and mass spectrometry. Journal of Chromatography. A. 1162: 117-25. PMID 17434173 DOI: 10.1016/J.Chroma.2007.03.096  0.336
2007 Zhao J, Patwa TH, Qiu W, Shedden K, Hinderer R, Misek DE, Anderson MA, Simeone DM, Lubman DM. Glycoprotein microarrays with multi-lectin detection: unique lectin binding patterns as a tool for classifying normal, chronic pancreatitis and pancreatic cancer sera. Journal of Proteome Research. 6: 1864-74. PMID 17428079 DOI: 10.1021/Pr070062P  0.483
2007 Heidt DG, Burant C, Simeone DM. Total pancreatectomy: indications, operative technique, and postoperative sequelae. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 11: 209-16. PMID 17390175 DOI: 10.1007/S11605-006-0025-7  0.363
2007 Huang EH, Heidt DG, Li CW, Simeone DM. Cancer stem cells: a new paradigm for understanding tumor progression and therapeutic resistance. Surgery. 141: 415-419. PMID 17383517 DOI: 10.1016/J.Surg.2006.12.015  0.392
2007 Ramachandran V, Arumugam T, Hwang RF, Greenson JK, Simeone DM, Logsdon CD. Adrenomedullin is expressed in pancreatic cancer and stimulates cell proliferation and invasion in an autocrine manner via the adrenomedullin receptor, ADMR. Cancer Research. 67: 2666-75. PMID 17363587 DOI: 10.1158/0008-5472.Can-06-3362  0.465
2007 Li C, Heidt DG, Dalerba P, Burant CF, Zhang L, Adsay V, Wicha M, Clarke MF, Simeone DM. Identification of pancreatic cancer stem cells Cancer Research. 67: 1030-1037. PMID 17283135 DOI: 10.1158/0008-5472.Can-06-2030  0.464
2007 Zhao J, Qiu W, Simeone DM, Lubman DM. N-linked glycosylation profiling of pancreatic cancer serum using capillary liquid phase separation coupled with mass spectrometric analysis. Journal of Proteome Research. 6: 1126-38. PMID 17249709 DOI: 10.1021/Pr0604458  0.389
2007 Yue T, Chen S, Goldstein I, Hollingsworth MA, Simeone D, Brand RE, Haab BB. PROFILING GLYCAN STRUCTURES ON MUCINS IN THE SERA OF PANCREATIC CANCER PATIENTS USING ANTIBODY ARRAYS Pancreas. 35: 437-438. DOI: 10.1097/01.Mpa.0000297820.29441.D1  0.386
2007 Wang L, Lee CJ, Heidt DG, Ljungman ME, Simeone DM. ATDC, A HIGHLY EXPRESSED PROTEIN IN PANCREATIC CANCER, CONTRIBUTES TO TUMORIGENICITY BY UPREGULATING WNT/β-CATENIN SIGNALING Pancreas. 35: 434. DOI: 10.1097/01.Mpa.0000297808.26412.87  0.374
2007 Zolotarevsky E, Kwon RS, Piraka CR, Wamsteker EJ, Elta GH, Simeone DM, Scheiman J, Pedroza JM, Anderson MA. Endoscopic Ultrasound with Fine Needle Aspiration (EUS-FNA) with Pancreatic Cyst Fluid DNA Analysis Influences Clinical Management in Patients with Cystic Lesions of the Pancreas Gastrointestinal Endoscopy. 65. DOI: 10.1016/J.Gie.2007.03.363  0.306
2006 Hong SH, Misek DE, Wang H, Puravs E, Hinderer R, Giordano TJ, Greenson JK, Brenner DE, Simeone DM, Logsdon CD, Hanash SM. Identification of a Specific Vimentin Isoform That Induces an Antibody Response in Pancreatic Cancer. Biomarker Insights. 1: 175-183. PMID 18769604  0.39
2006 Patwa TH, Zhao J, Anderson MA, Simeone DM, Lubman DM. Screening of glycosylation patterns in serum using natural glycoprotein microarrays and multi-lectin fluorescence detection. Analytical Chemistry. 78: 6411-21. PMID 16970316 DOI: 10.1021/Ac060726Z  0.375
2006 Zhao J, Simeone DM, Heidt D, Anderson MA, Lubman DM. Comparative serum glycoproteomics using lectin selected sialic acid glycoproteins with mass spectrometric analysis: application to pancreatic cancer serum. Journal of Proteome Research. 5: 1792-802. PMID 16823988 DOI: 10.1021/Pr060034R  0.362
2006 Newman EA, Simeone DM, Mulholland MW. Adjuvant treatment strategies for pancreatic cancer. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 10: 916-26. PMID 16769552 DOI: 10.1016/J.Gassur.2005.10.018  0.453
2006 Simeone DM, Zhang L, Treutelaar MK, Zhang L, Graziano K, Logsdon CD, Burant CF. Islet hypertrophy following pancreatic disruption of Smad4 signaling. American Journal of Physiology. Endocrinology and Metabolism. 291: E1305-16. PMID 16735447 DOI: 10.1152/Ajpendo.00561.2005  0.307
2006 Zhang L, Chenwei L, Mahmood R, van Golen K, Greenson J, Li G, D'Silva NJ, Li X, Burant CF, Logsdon CD, Simeone DM. Identification of a putative tumor suppressor gene Rap1GAP in pancreatic cancer. Cancer Research. 66: 898-906. PMID 16424023 DOI: 10.1158/0008-5472.Can-05-3025  0.489
2006 Desai SP, Ben-Josef E, Lawrence TJ, Francis IR, Greenson JK, Alfred CE, Colletti LM, Simeone DM, Normolle DP, Zalupski MM. A phase I study of oxaliplatin, full-dose gemcitabine and concurrent radiation therapy in patients with pancreatic cancer Journal of Clinical Oncology. 24: 4107-4107. DOI: 10.1200/Jco.2006.24.18_Suppl.4107  0.306
2006 Heidt DG, Li C, Mollenberg N, Clarke MF, Simeone D. Identification of pancreatic cancer stem cells Journal of Surgical Research. 130: 194-195. DOI: 10.1016/J.Jss.2005.11.093  0.448
2006 Lee C, Zhang L, Uhler M, Simeone D. A TGFβ-induced Smad complex directly activates PKA in pancreatic acinar cells and regulates pancreatic acinar cell growth Journal of Surgical Research. 130: 171. DOI: 10.1016/J.Jss.2005.11.030  0.385
2005 Arumugam T, Simeone DM, Van Golen K, Logsdon CD. S100P promotes pancreatic cancer growth, survival, and invasion. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 5356-64. PMID 16061848 DOI: 10.1158/1078-0432.CCR-05-0092  0.329
2005 Zhang L, Heidt DG, Simeone DM, Burant CF. Prospective Identification Of Adult Pancreatic Stem/Progenitor Cells Pancreas. 31: 480. DOI: 10.1097/01.Mpa.0000193801.74497.D3  0.321
2005 Li C, Heidt DG, Mollenberg N, Clarke M, Simeone DM. Identification Of Pancreatic Cancer Stem Cells Pancreas. 31: 452. DOI: 10.1097/01.Mpa.0000193704.00116.C2  0.448
2005 Heidt D, Birkmeyer JD, Sun Y, Ben-Josef E, Simeone DM. Effect Of Adjuvant Radiation Treatment On Survival Following Pancreaticoduodenectomy For Pancreatic Cancer: A Population-Based Study Pancreas. 31: 446. DOI: 10.1097/01.Mpa.0000193684.67835.6B  0.375
2005 Simeone DM. Pancreatic Cancer: Methods and Protocols Gastroenterology. 129: 1136. DOI: 10.1053/J.Gastro.2005.07.035  0.435
2005 Anderson M, Ji B, Scheiman JM, Song J, Weinman BM, Simeone D, Logsdon C. Molecular Markers From EUS Fine Needle Specimens Can Differentiate Pancreatic Neoplasia Requiring Surgery From Chronic Pancreatitis and Other Benign Conditions of the Pancreas Gastrointestinal Endoscopy. 61. DOI: 10.1016/S0016-5107(05)00594-8  0.351
2004 Binkley CE, Zhang L, Greenson JK, Giordano TJ, Kuick R, Misek D, Hanash S, Logsdon CD, Simeone DM. The molecular basis of pancreatic fibrosis: common stromal gene expression in chronic pancreatitis and pancreatic adenocarcinoma. Pancreas. 29: 254-63. PMID 15502640 DOI: 10.1097/00006676-200411000-00003  0.434
2004 Hong SH, Misek DE, Wang H, Puravs E, Giordano TJ, Greenson JK, Brenner DE, Simeone DM, Logsdon CD, Hanash SM. An autoantibody-mediated immune response to calreticulin isoforms in pancreatic cancer. Cancer Research. 64: 5504-10. PMID 15289361 DOI: 10.1158/0008-5472.Can-04-0077  0.492
2004 Okami J, Simeone DM, Logsdon CD. Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer. Cancer Research. 64: 5338-46. PMID 15289340 DOI: 10.1158/0008-5472.Can-04-0089  0.455
2004 Ji B, Anderson M, Song J, Simeone D, Weinman B, Scheiman J, Logsdon CD. Pancreatic Cancer Associated Gene Expression From Fna Samples Differentiates Neoplastic From Benign Pancreatic Diseases. Pancreas. 29: 337. DOI: 10.1097/00006676-200411000-00054  0.43
2004 Arumugam T, Simeone DM, Logsdon CD. S100P Increases Pancreatic Cancer Growth And Invasion. Pancreas. 29: 333. DOI: 10.1097/00006676-200411000-00040  0.411
2004 Ramachandran V, Arimugam T, Li G, Logsdon CD, Simeone DM. Adrenomedullin Is Overexpressed In Pancreatic Cancer And Stimulates Cell Growth And Invasion. Pancreas. 29: 331. DOI: 10.1097/00006676-200411000-00034  0.431
2003 Shedden KA, Taylor JM, Giordano TJ, Kuick R, Misek DE, Rennert G, Schwartz DR, Gruber SB, Logsdon C, Simeone D, Kardia SL, Greenson JK, Cho KR, Beer DG, Fearon ER, et al. Accurate molecular classification of human cancers based on gene expression using a simple classifier with a pathological tree-based framework. The American Journal of Pathology. 163: 1985-95. PMID 14578198 DOI: 10.1016/S0002-9440(10)63557-2  0.33
2003 Treutelaar MK, Skidmore JM, Dias-Leme CL, Hara M, Zhang L, Simeone D, Martin DM, Burant CF. Nestin-lineage cells contribute to the microvasculature but not endocrine cells of the islet. Diabetes. 52: 2503-12. PMID 14514633 DOI: 10.2337/Diabetes.52.10.2503  0.342
2003 Logsdon CD, Simeone DM, Binkley C, Arumugam T, Greenson JK, Giordano TJ, Misek DE, Kuick R, Hanash S. Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer. Cancer Research. 63: 2649-57. PMID 12750293  0.368
2003 Arumugam T, Simeone D, Logsdon C. S100P is expressed in pancreatic adenocarcinoma and stimulates pancreatic cancer cell proliferation and survival Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)81457-9  0.396
2003 Okami J, Arumugam T, Simeone D, Logsdon C. Genes down-regulated in pancreatic adenocarcinoma affect cell survival: Reintroduction of proapoptotic BNIP3 leads to cancer cell death Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)80101-4  0.417
2003 Binkley CE, Davis MA, Zhang L, Lawrence TS, Logsdon CD, Simeone DM. The ataxia telangiectasia group D associated gene confers a cellular survival advantage in pancreatic adenocarcinoma Journal of Surgical Research. 114: 240. DOI: 10.1016/J.Jss.2003.08.131  0.377
2002 Ji B, Bi Y, Simeone D, Mortensen RM, Logsdon CD. Human pancreatic acinar cells do not respond to cholecystokinin. Pharmacology & Toxicology. 91: 327-32. PMID 12688376 DOI: 10.1034/J.1600-0773.2002.910610.X  0.308
2002 Burant CF, Simeone DM. Connecting islet development and developing useful islets. Trends in Endocrinology and Metabolism: Tem. 13: 48-9. PMID 11854014 DOI: 10.1016/S1043-2760(01)00555-0  0.356
2001 Ji B, Bi Y, Simeone D, Mortensen RM, Logsdon CD. Human pancreatic acinar cells lack functional responses to cholecystokinin and gastrin. Gastroenterology. 121: 1380-90. PMID 11729117 DOI: 10.1053/Gast.2001.29557  0.333
2001 Zhang L, Vanleeuwen K, Surg G, Logsdon CD, Simeone DM. TGFβ activation of cAMP responsive element-binding protein (CREB) is dependent on PKA and smads in pancreatic acinar cells Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)81731-3  0.313
2000 Simeone DM, Pham T, Logsdon CD. Disruption of TGFbeta signaling pathways in human pancreatic cancer cells. Annals of Surgery. 232: 73-80. PMID 10862198 DOI: 10.1097/00000658-200007000-00011  0.411
2000 Zhang L, Logsdon CD, Simeone DM. TGFB-mediated growth inhibition and induction of P21 in pancreatic acinar cells is blocked by adenoviral gene transfer of dominant negative DPC4 Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)84977-X  0.307
2000 vanLeeuwen K, Zhang L, Han B, Logsdon CD, Simeone DM. Transcription factor activation by TGFB in pancreatic acinar cells: role of DPC4 and map kinases Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)83898-6  0.309
2000 vanLeeuwen K, Pham T, Logsdon CD, Simeone DM. TGFb inhibits growth in a human pancreatic cancer cell line lacking DPC4 Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)81551-6  0.413
1997 Simeone DM, Cascarelli A, Logsdon CD. Adenoviral-mediated gene transfer of a constitutively active retinoblastoma gene inhibits human pancreatic tumor cell proliferation Surgery. 122: 428-434. PMID 9288150 DOI: 10.1016/S0039-6060(97)90036-2  0.453
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