| Year |
Citation |
Score |
| 2021 |
Canman CE. Which Holds the Key to BRCAness: Inability to Repair the Break, Protect the Fork, or Prevent the Gap? Cancer Research. 81: 1214-1215. PMID 33822743 DOI: 10.1158/0008-5472.CAN-20-4340 |
0.432 |
|
| 2020 |
Parsels LA, Engelke CG, Parsels J, Flanagan SA, Zhang Q, Tanska D, Wahl DR, Canman CE, Lawrence TS, Morgan MA. Combinatorial efficacy of olaparib with radiation and ATR inhibitor requires PARP1 protein in homologous recombination proficient pancreatic cancer. Molecular Cancer Therapeutics. PMID 33268569 DOI: 10.1158/1535-7163.MCT-20-0365 |
0.386 |
|
| 2018 |
Morgan MA, Canman CE. Replication Stress: An Achilles' Heel of Glioma Cancer Stem–like Cells Cancer Research. 78: 6713-6716. PMID 30498082 DOI: 10.1158/0008-5472.Can-18-2439 |
0.458 |
|
| 2016 |
Fritzen R, Delbos F, De Smet A, Palancade B, Canman CE, Aoufouchi S, Weill JC, Reynaud CA, Storck S. A single aspartate mutation in the conserved catalytic site of Rev3L generates a hypomorphic phenotype in vivo and in vitro. Dna Repair. PMID 27481099 DOI: 10.1016/J.Dnarep.2016.07.002 |
0.388 |
|
| 2014 |
Ziv O, Zeisel A, Mirlas-Neisberg N, Swain U, Nevo R, Ben-Chetrit N, Martelli MP, Rossi R, Schiesser S, Canman CE, Carell T, Geacintov NE, Falini B, Domany E, Livneh Z. Identification of novel DNA-damage tolerance genes reveals regulation of translesion DNA synthesis by nucleophosmin. Nature Communications. 5: 5437. PMID 25421715 DOI: 10.1038/Ncomms6437 |
0.458 |
|
| 2014 |
Inoue A, Kikuchi S, Hishiki A, Shao Y, Heath R, Evison BJ, Actis M, Canman CE, Hashimoto H, Fujii N. A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin. The Journal of Biological Chemistry. 289: 7109-20. PMID 24474685 DOI: 10.1074/Jbc.M113.520429 |
0.514 |
|
| 2014 |
Prensner JR, Chen W, Iyer MK, Cao Q, Ma T, Han S, Sahu A, Malik R, Wilder-Romans K, Navone N, Logothetis CJ, Araujo JC, Pisters LL, Tewari AK, Canman CE, et al. PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer. Cancer Research. 74: 1651-60. PMID 24473064 DOI: 10.1158/0008-5472.Can-13-3159 |
0.39 |
|
| 2014 |
Wang L, Yang H, Palmbos PL, Ney G, Detzler TA, Coleman D, Leflein J, Davis M, Zhang M, Tang W, Hicks JK, Helchowski CM, Prasad J, Lawrence TS, Xu L, ... ... Canman CE, et al. ATDC/TRIM29 phosphorylation by ATM/MAPKAP kinase 2 mediates radioresistance in pancreatic cancer cells. Cancer Research. 74: 1778-88. PMID 24469230 DOI: 10.1158/0008-5472.Can-13-2289 |
0.539 |
|
| 2013 |
Ladd B, Ackroyd JJ, Hicks JK, Canman CE, Flanagan SA, Shewach DS. Inhibition of homologous recombination with vorinostat synergistically enhances ganciclovir cytotoxicity. Dna Repair. 12: 1114-21. PMID 24231389 DOI: 10.1016/J.Dnarep.2013.10.008 |
0.521 |
|
| 2013 |
Helchowski CM, Skow LF, Roberts KH, Chute CL, Canman CE. A small ubiquitin binding domain inhibits ubiquitin-dependent protein recruitment to DNA repair foci. Cell Cycle (Georgetown, Tex.). 12: 3749-58. PMID 24107634 DOI: 10.4161/Cc.26640 |
0.512 |
|
| 2013 |
Tian F, Sharma S, Zou J, Lin SY, Wang B, Rezvani K, Wang H, Parvin JD, Ludwig T, Canman CE, Zhang D. BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade. Proceedings of the National Academy of Sciences of the United States of America. 110: 13558-63. PMID 23901102 DOI: 10.1073/Pnas.1306534110 |
0.518 |
|
| 2013 |
Sharma S, Helchowski CM, Canman CE. The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability. Mutation Research. 743: 97-110. PMID 23195997 DOI: 10.1016/J.Mrfmmm.2012.11.002 |
0.501 |
|
| 2012 |
Sharma S, Canman CE. REV1 and DNA polymerase zeta in DNA interstrand crosslink repair. Environmental and Molecular Mutagenesis. 53: 725-40. PMID 23065650 DOI: 10.1002/Em.21736 |
0.492 |
|
| 2012 |
Sharma S, Shah NA, Joiner AM, Roberts KH, Canman CE. DNA polymerase ζ is a major determinant of resistance to platinum-based chemotherapeutic agents. Molecular Pharmacology. 81: 778-87. PMID 22387291 DOI: 10.1124/Mol.111.076828 |
0.501 |
|
| 2012 |
Sharma S, Hicks JK, Chute CL, Brennan JR, Ahn JY, Glover TW, Canman CE. REV1 and polymerase ζ facilitate homologous recombination repair. Nucleic Acids Research. 40: 682-91. PMID 21926160 DOI: 10.1093/Nar/Gkr769 |
0.517 |
|
| 2012 |
Sharma S, Canman CE. Abstract 2115: REV1, DNA polymerase ≤ and the fanconi anemia proteins FANCD2 and FANCI function together during repair Cancer Research. 72: 2115-2115. DOI: 10.1158/1538-7445.Am2012-2115 |
0.52 |
|
| 2010 |
Morgan MA, Parsels LA, Zhao L, Parsels JD, Davis MA, Hassan MC, Arumugarajah S, Hylander-Gans L, Morosini D, Simeone DM, Canman CE, Normolle DP, Zabludoff SD, Maybaum J, Lawrence TS. Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair. Cancer Research. 70: 4972-81. PMID 20501833 DOI: 10.1158/0008-5472.Can-09-3573 |
0.429 |
|
| 2010 |
Hicks JK, Chute CL, Paulsen MT, Ragland RL, Howlett NG, Guéranger Q, Glover TW, Canman CE. Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links. Molecular and Cellular Biology. 30: 1217-30. PMID 20028736 DOI: 10.1128/Mcb.00993-09 |
0.502 |
|
| 2010 |
Morgan MA, Parsels L, Zhao L, Parsels J, Davis M, Arumugarajah S, Canman C, Zabludoff S, Maybaum J, Lawrence T. Abstract 491: The roles of homologous recombination repair and cell cycle checkpoints in radiosensitization by the Chk1/2 inhibitor, AZD7762 Cancer Research. 70: 491-491. DOI: 10.1158/1538-7445.Am10-491 |
0.447 |
|
| 2010 |
Parsels LA, Morgan MA, Tanska DM, Parsels JD, Davis MA, Hassan MC, Arumugarajah S, Hylander-Gans L, Morosini D, Zhao L, Simeone DM, Canman CE, Normolle DP, Zabludoff SD, Lawrence TS, et al. Abstract 1765: Preclinical optimization of the Chk1/2 inhibitor AZD7762 in combination with gemcitabine in pancreatic cancer Cancer Research. 70: 1765-1765. DOI: 10.1158/1538-7445.Am10-1765 |
0.391 |
|
| 2009 |
Parsels LA, Morgan MA, Tanska DM, Parsels JD, Palmer BD, Booth RJ, Denny WA, Canman CE, Kraker AJ, Lawrence TS, Maybaum J. Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells. Molecular Cancer Therapeutics. 8: 45-54. PMID 19139112 DOI: 10.1158/1535-7163.Mct-08-0662 |
0.448 |
|
| 2009 |
Derheimer FA, Hicks JK, Paulsen MT, Canman CE, Ljungman M. Psoralen-lnduced DNA interstrand cross-links block transcription and induce p53 in an ataxia-telangiectasia and rad3-related-dependent manner Molecular Pharmacology. 75: 599-607. PMID 19064630 DOI: 10.1124/Mol.108.051698 |
0.521 |
|
| 2006 |
Nyati MK, Feng FY, Maheshwari D, Varambally S, Zielske SP, Ahsan A, Chun PY, Arora VA, Davis MA, Jung M, Ljungman M, Canman CE, Chinnaiyan AM, Lawrence TS. Ataxia telangiectasia mutated down-regulates phospho-extracellular signal-regulated kinase 1/2 via activation of MKP-1 in response to radiation. Cancer Research. 66: 11554-9. PMID 17178844 DOI: 10.1158/0008-5472.Can-06-1935 |
0.435 |
|
| 2004 |
Garg R, Callens S, Lim DS, Canman CE, Kastan MB, Xu B. Chromatin association of rad17 is required for an ataxia telangiectasia and rad-related kinase-mediated S-phase checkpoint in response to low-dose ultraviolet radiation. Molecular Cancer Research : McR. 2: 362-9. PMID 15235112 |
0.312 |
|
| 2003 |
Lee JH, Xu B, Lee CH, Ahn JY, Song MS, Lee H, Canman CE, Lee JS, Kastan MB, Lim DS. Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage. Molecular Cancer Research : McR. 1: 674-81. PMID 12861053 |
0.356 |
|
| 2003 |
Canman CE. Checkpoint mediators: relaying signals from DNA strand breaks. Current Biology : Cb. 13: R488-90. PMID 12814569 |
0.427 |
|
| 2002 |
Ahn JY, Li X, Davis HL, Canman CE. Phosphorylation of threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated domain. The Journal of Biological Chemistry. 277: 19389-95. PMID 11901158 DOI: 10.1074/Jbc.M200822200 |
0.351 |
|
| 2001 |
Canman CE. Replication checkpoint: Preventing mitotic catastrophe Current Biology. 11. PMID 11250164 DOI: 10.1016/S0960-9822(01)00057-4 |
0.431 |
|
| 1999 |
Kim ST, Lim DS, Canman CE, Kastan MB. Substrate Specificities and Identification of Putative Substrates of ATM Kinase Family Members Journal of Biological Chemistry. 274: 37538-37543. PMID 10608806 DOI: 10.1074/Jbc.274.53.37538 |
0.445 |
|
| 1998 |
Canman CE, Lim DS. The role of ATM in DNA damage responses and cancer Oncogene. 17: 3301-3308. PMID 9916992 DOI: 10.1038/Sj.Onc.1202577 |
0.521 |
|
| 1998 |
Canman CE, Lim DS, Cimprich KA, Taya Y, Tamai K, Sakaguchi K, Appella E, Kastan MB, Siliciano JD. Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science (New York, N.Y.). 281: 1677-9. PMID 9733515 DOI: 10.1126/Science.281.5383.1677 |
0.417 |
|
| 1998 |
Canman CE, Kastan MB. Small contribution of G1 checkpoint control manipulation to modulation of p53-mediated apoptosis. Oncogene. 16: 957-966. PMID 9519869 DOI: 10.1038/Sj.Onc.1201612 |
0.381 |
|
| 1997 |
Siliciano JD, Canman CE, Taya Y, Sakaguchi K, Appella E, Kastan MB. Dna Damage Induces Phosphorylation Of The Amino Terminus Of P53 Genes & Development. 11: 3471-3481. PMID 9407038 DOI: 10.1101/Gad.11.24.3471 |
0.452 |
|
| 1997 |
Metcalfe SM, Canman CE, Milner J, Morris RE, Goldman S, Kastan MB. Rapamycin and p53 act on different pathways to induce G1 arrest in mammalian cells Oncogene. 15: 1635-1642. PMID 9349496 DOI: 10.1038/Sj.Onc.1201341 |
0.477 |
|
| 1997 |
Canman CE, Kastan MB. Role Of P53 In Apoptosis Advances in Pharmacology. 41: 429-460. PMID 9204155 DOI: 10.1016/S1054-3589(08)61068-6 |
0.414 |
|
| 1997 |
Baskaran R, Wood LD, Whitaker LL, Canman CE, Morgan SE, Xu Y, Barlow C, Baltimore D, Wynshaw-Boris A, Kastan MB, Wang JY. Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation. Nature. 387: 516-9. PMID 9168116 DOI: 10.1038/387516A0 |
0.36 |
|
| 1995 |
Canman CE, Gilmer TM, Coutts SB, Kastan MB. Growth factor modulation of p53-mediated growth arrest versus apoptosis. Genes & Development. 9: 600-611. PMID 7698649 DOI: 10.1101/Gad.9.5.600 |
0.392 |
|
| 1995 |
Kastan MB, Canman CE, Leonard CJ. P53, cell cycle control and apoptosis: implications for cancer. Cancer Metastasis Reviews. 14: 3-15. PMID 7606818 DOI: 10.1007/Bf00690207 |
0.381 |
|
| 1995 |
Canman CE, Kastan MB. Induction of apoptosis by tumor suppressor genes and oncogenes Seminars in Cancer Biology. 6: 17-25. PMID 7548837 DOI: 10.1006/Scbi.1995.0003 |
0.445 |
|
| 1995 |
Lawrence TS, Davis MA, Chang EY, Canman CE, Maybaum J, Radany EH. Lack of dependence of 5-fluorodeoxyuridine-mediated radiosensitization on cytotoxicity. Radiation Research. 143: 281-285. DOI: 10.2307/3579214 |
0.349 |
|
| 1994 |
Canman CE, Chen C-, Lee M-, Kastan MB. DNA Damage Responses: p53 Induction, Cell Cycle Perturbations, and Apoptosis Cold Spring Harbor Symposia On Quantitative Biology. 59: 277-286. PMID 7587079 DOI: 10.1101/Sqb.1994.059.01.032 |
0.499 |
|
| 1992 |
Canman CE, Tang H, Normolle DP, Lawrence TS, Maybaum J. Variations in patterns of DNA damage induced in human colorectal tumor cells by 5-fluorodeoxyuridine: implications for mechanisms of resistance and cytotoxicity Proceedings of the National Academy of Sciences of the United States of America. 89: 10474-10478. PMID 1438236 DOI: 10.1073/Pnas.89.21.10474 |
0.468 |
|
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