John Petrini - Publications

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 
Area:
Molecular Biology, Genetics

90 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wardlaw CP, Petrini JHJ. ISG15: A link between innate immune signaling, DNA replication, and genome stability. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e2300042. PMID 37147792 DOI: 10.1002/bies.202300042  0.339
2022 Belhadj S, Khurram A, Bandlamudi C, Palou-Márquez G, Ravichandran V, Steinsnyder Z, Wildman T, Catchings A, Kemel Y, Mukherjee S, Fesko B, Arora K, Mehine M, Dandiker S, Izhar A, ... Petrini J, et al. NBN pathogenic germline variants are associated with pan-cancer susceptibility and in vitro DNA damage response defects. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 36346689 DOI: 10.1158/1078-0432.CCR-22-1703  0.306
2022 Wardlaw CP, Petrini JHJ. ISG15 conjugation to proteins on nascent DNA mitigates DNA replication stress. Nature Communications. 13: 5971. PMID 36216822 DOI: 10.1038/s41467-022-33535-y  0.426
2022 Fernandez KC, Feeney L, Smolkin RM, Yen WF, Matthews AJ, Alread W, Petrini JHJ, Chaudhuri J. The structure-selective endonucleases GEN1 and MUS81 mediate complementary functions in safeguarding the genome of proliferating B lymphocytes. Elife. 11. PMID 36190107 DOI: 10.7554/eLife.77073  0.35
2020 Chansel-Da Cruz M, Hohl M, Ceppi I, Kermasson L, Maggiorella L, Modesti M, de Villartay JP, Ileri T, Cejka P, Petrini JHJ, Revy P. A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans. Cell Reports. 33: 108559. PMID 33378670 DOI: 10.1016/j.celrep.2020.108559  0.445
2020 Fagin JA, Petrini JH. Oncogene-induced DNA damage: cyclic AMP steps into the ring. The Journal of Clinical Investigation. PMID 32986019 DOI: 10.1172/JCI142237  0.37
2020 Carbone M, Arron ST, Beutler B, Bononi A, Cavenee W, Cleaver JE, Croce CM, D'Andrea A, Foulkes WD, Gaudino G, Groden JL, Henske EP, Hickson ID, Hwang PM, Kolodner RD, ... ... Petrini JH, et al. Tumour predisposition and cancer syndromes as models to study gene-environment interactions. Nature Reviews. Cancer. PMID 32472073 DOI: 10.1038/S41568-020-0265-Y  0.37
2020 Wu W, Bhowmick R, Vogel I, Özer Ö, Ghisays F, Thakur RS, Sanchez de Leon E, Richter PH, Ren L, Petrini JH, Hickson ID, Liu Y. RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome. Nature Structural & Molecular Biology. 27: 424-437. PMID 32398827 DOI: 10.1038/S41594-020-0408-6  0.305
2020 Hohl M, Mojumdar A, Hailemariam S, Kuryavyi V, Ghisays F, Sorenson K, Chang M, Taylor BS, Patel DJ, Burgers PM, Cobb JA, Petrini JHJ. Modeling cancer genomic data in yeast reveals selection against ATM function during tumorigenesis. Plos Genetics. 16: e1008422. PMID 32187176 DOI: 10.1371/Journal.Pgen.1008422  0.444
2020 Fagan-Solis KD, Simpson DA, Kumar RJ, Martelotto LG, Mose LE, Rashid NU, Ho AY, Powell SN, Wen YH, Parker JS, Reis-Filho JS, Petrini JHJ, Gupta GP. A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability. Cell Reports. 30: 1385-1399.e7. PMID 32023457 DOI: 10.1016/J.Celrep.2020.01.020  0.447
2019 Mojumdar A, Sorenson K, Hohl M, Toulouze M, Lees-Miller SP, Dubrana K, Petrini JHJ, Cobb JA. Nej1 Interacts with Mre11 to Regulate Tethering and Dna2 Binding at DNA Double-Strand Breaks. Cell Reports. 28: 1564-1573.e3. PMID 31390569 DOI: 10.1016/J.Celrep.2019.07.018  0.437
2019 Kim JH, Penson AV, Taylor BS, Petrini JHJ. Nbn-Mre11 interaction is required for tumor suppression and genomic integrity. Proceedings of the National Academy of Sciences of the United States of America. PMID 31285322 DOI: 10.1073/pnas.1905305116  0.335
2019 Huang G, Kaufman AJ, Ryan RJH, Romin Y, Huryn L, Bains S, Manova-Todorova K, Morris PL, Hunnicutt GR, Adelman CA, Petrini JHJ, Ramanathan Y, Singh B. Mouse DCUN1D1 (SCCRO) is required for spermatogenetic individualization. Plos One. 14: e0209995. PMID 30653527 DOI: 10.1371/Journal.Pone.0209995  0.659
2019 Fagan-Solis K, Simpson D, Kapustina M, Martelotto L, Reis-Filho J, Petrini J, Gupta G. Abstract P1-06-08: A p53-independent DNA damage response that regulates breast cancer phenotypes Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P1-06-08  0.473
2018 Hung PJ, Johnson B, Chen BR, Byrum AK, Bredemeyer AL, Yewdell WT, Johnson TE, Lee BJ, Deivasigamani S, Hindi I, Amatya P, Gross ML, Paull TT, Pisapia DJ, Chaudhuri J, ... Petrini JJH, et al. MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining. Molecular Cell. PMID 30017584 DOI: 10.1016/J.Molcel.2018.06.018  0.403
2017 Henssen AG, Reed C, Jiang E, Garcia HD, von Stebut J, MacArthur IC, Hundsdoerfer P, Kim JH, de Stanchina E, Kuwahara Y, Hosoi H, Ganem NJ, Dela Cruz F, Kung AL, Schulte JH, ... Petrini JH, et al. Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors. Science Translational Medicine. 9. PMID 29093183 DOI: 10.1126/Scitranslmed.Aam9078  0.334
2017 Kim JH, Grosbart M, Anand R, Wyman C, Cejka P, Petrini JH. The Mre11-Nbs1 Interface Is Essential for Viability and Tumor Suppression. Cell Reports. 18: 496-507. PMID 28076792 DOI: 10.1016/J.Celrep.2016.12.035  0.492
2017 Henssen A, Reed C, Jiang E, Wai W, Stanchina Ed, Kuwahara Y, Hosoi H, Schulte JH, Ganem N, Petrini J, Kentsis A. Abstract 3002: Therapeutic targeting of PGBD5-induced DNA repair dependence in pediatric solid tumors Cancer Research. 77: 3002-3002. DOI: 10.1158/1538-7445.Am2017-3002  0.392
2016 Rocha PP, Raviram R, Fu Y, Kim J, Luo VM, Aljoufi A, Swanzey E, Pasquarella A, Balestrini A, Miraldi ER, Bonneau R, Petrini J, Schotta G, Skok JA. A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination. Cell Reports. PMID 27320916 DOI: 10.1016/J.Celrep.2016.05.073  0.413
2016 Asai T, Hatlen MA, Lossos C, Ndiaye-Lobry D, Deblasio A, Murata K, Fleisher M, Cortizas EM, Verdun RE, Petrini J, Nimer SD. Generation of a novel, multi-stage, progressive, and transplantable model of plasma cell neoplasms. Scientific Reports. 6: 22760. PMID 26961797 DOI: 10.1038/Srep22760  0.336
2016 Inagaki A, Roset R, Petrini JH. Functions of the MRE11 complex in the development and maintenance of oocytes. Chromosoma. 125: 151-62. PMID 26232174 DOI: 10.1007/s00412-015-0535-8  0.53
2015 Balestrini A, Nicolas L, Yang-Lott K, Guryanova OA, Levine RL, Bassing CH, Chaudhuri J, Petrini JH. Defining ATM-independent Functions of the Mre11 Complex with a Novel Mouse Model. Molecular Cancer Research : McR. PMID 26538284 DOI: 10.1158/1541-7786.Mcr-15-0281  0.535
2015 Hohl M, Kochańczyk T, Tous C, Aguilera A, Krężel A, Petrini JH. Interdependence of the rad50 hook and globular domain functions. Molecular Cell. 57: 479-91. PMID 25601756 DOI: 10.1016/j.molcel.2014.12.018  0.347
2014 Al-Ahmadie H, Iyer G, Hohl M, Asthana S, Inagaki A, Schultz N, Hanrahan AJ, Scott SN, Brannon AR, McDermott GC, Pirun M, Ostrovnaya I, Kim P, Socci ND, Viale A, ... ... Petrini JH, et al. Synthetic lethality in ATM-deficient RAD50-mutant tumors underlies outlier response to cancer therapy. Cancer Discovery. 4: 1014-21. PMID 24934408 DOI: 10.1158/2159-8290.Cd-14-0380  0.325
2014 Katyal S, Lee Y, Nitiss KC, Downing SM, Li Y, Shimada M, Zhao J, Russell HR, Petrini JH, Nitiss JL, McKinnon PJ. Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes. Nature Neuroscience. 17: 813-21. PMID 24793032 DOI: 10.1038/nn.3715  0.416
2014 Roth S, Rottach A, Lotz-Havla AS, Laux V, Muschaweckh A, Gersting SW, Muntau AC, Hopfner KP, Jin L, Vanness K, Petrini JH, Drexler I, Leonhardt H, Ruland J. Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production. Nature Immunology. 15: 538-45. PMID 24777530 DOI: 10.1038/ni.2888  0.331
2014 Roset R, Inagaki A, Hohl M, Brenet F, Lafrance-Vanasse J, Lange J, Scandura JM, Tainer JA, Keeney S, Petrini JH. The Rad50 hook domain regulates DNA damage signaling and tumorigenesis. Genes & Development. 28: 451-62. PMID 24532689 DOI: 10.1101/Gad.236745.113  0.426
2014 Petrini J. Abstract SY33-04: Tumor suppression by the DNA damage response Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Sy33-04  0.468
2013 Gupta GP, Vanness K, Barlas A, Manova-Todorova KO, Wen YH, Petrini JH. The Mre11 complex suppresses oncogene-driven breast tumorigenesis and metastasis. Molecular Cell. 52: 353-65. PMID 24120666 DOI: 10.1016/j.molcel.2013.09.001  0.332
2013 Balestrini A, Ristic D, Dionne I, Liu XZ, Wyman C, Wellinger RJ, Petrini JH. The Ku heterodimer and the metabolism of single-ended DNA double-strand breaks. Cell Reports. 3: 2033-45. PMID 23770241 DOI: 10.1016/J.Celrep.2013.05.026  0.41
2013 Jalas C, Fedick A, Ballew BJ, Alter BP, Giri N, Boulton S, Offit K, Petrini J, Treff N, Savage SA. Higher Than Expected Carrier Frequency Of The Dyskeratosis Congenita RTEL1 p.Arg1264His recessive Founder In Individuals Of Ashkenazi Jewish Ancestry Blood. 122: 1228-1228. DOI: 10.1182/Blood.V122.21.1228.1228  0.322
2012 Wohlbold L, Merrick KA, De S, Amat R, Kim JH, Larochelle S, Allen JJ, Zhang C, Shokat KM, Petrini JH, Fisher RP. Chemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cells. Plos Genetics. 8: e1002935. PMID 22927831 DOI: 10.1371/Journal.Pgen.1002935  0.432
2012 Tittel-Elmer M, Lengronne A, Davidson MB, Bacal J, François P, Hohl M, Petrini JH, Pasero P, Cobb JA. Cohesin association to replication sites depends on rad50 and promotes fork restart. Molecular Cell. 48: 98-108. PMID 22885006 DOI: 10.1016/j.molcel.2012.07.004  0.421
2012 Lovejoy CA, Li W, Reisenweber S, Thongthip S, Bruno J, de Lange T, De S, Petrini JH, Sung PA, Jasin M, Rosenbluh J, Zwang Y, Weir BA, Hatton C, Ivanova E, et al. Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway. Plos Genetics. 8: e1002772. PMID 22829774 DOI: 10.1371/Journal.Pgen.1002772  0.372
2012 Foster SS, De S, Johnson LK, Petrini JH, Stracker TH. Cell cycle- and DNA repair pathway-specific effects of apoptosis on tumor suppression. Proceedings of the National Academy of Sciences of the United States of America. 109: 9953-8. PMID 22670056 DOI: 10.1073/pnas.1120476109  0.471
2012 Asai T, Menendez S, Ndiaye-Lobry D, Deblasio AR, Murata K, Fleisher M, Petrini J, Nimer SD. Generation of a Novel, Multi-Stage, Progressive, and Transplantable Model of Multiple Myeloma Blood. 120: 327-327. DOI: 10.1182/Blood.V120.21.327.327  0.386
2011 Hohl M, Kwon Y, Galván SM, Xue X, Tous C, Aguilera A, Sung P, Petrini JH. The Rad50 coiled-coil domain is indispensable for Mre11 complex functions. Nature Structural & Molecular Biology. 18: 1124-31. PMID 21892167 DOI: 10.1038/Nsmb.2116  0.324
2011 Foster SS, Balestrini A, Petrini JH. Functional interplay of the Mre11 nuclease and Ku in the response to replication-associated DNA damage. Molecular and Cellular Biology. 31: 4379-89. PMID 21876003 DOI: 10.1128/MCB.05854-11  0.47
2011 Stracker TH, Petrini JH. The MRE11 complex: starting from the ends. Nature Reviews. Molecular Cell Biology. 12: 90-103. PMID 21252998 DOI: 10.1038/nrm3047  0.476
2010 Squatrito M, Brennan CW, Helmy K, Huse JT, Petrini JH, Holland EC. Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas. Cancer Cell. 18: 619-29. PMID 21156285 DOI: 10.1016/j.ccr.2010.10.034  0.316
2010 Hakem R, Hande MP, Petrini J, Slijepcevic P. Genome Integrity - a new open access journal. Genome Integrity. 1: 1. PMID 20678251 DOI: 10.1186/2041-9414-1-1  0.411
2009 Brugmans L, Verkaik NS, Kunen M, van Drunen E, Williams BR, Petrini JH, Kanaar R, Essers J, van Gent DC. NBS1 cooperates with homologous recombination to counteract chromosome breakage during replication. Dna Repair. 8: 1363-70. PMID 19782649 DOI: 10.1016/J.Dnarep.2009.09.002  0.491
2009 Attwooll CL, Akpinar M, Petrini JH. The mre11 complex and the response to dysfunctional telomeres. Molecular and Cellular Biology. 29: 5540-51. PMID 19667076 DOI: 10.1128/MCB.00479-09  0.448
2009 Muzi-Falconi M, Petrini J. Checkpoint response to DNA damage. Dna Repair. 8: 973. PMID 19648065 DOI: 10.1016/J.Dnarep.2009.07.005  0.449
2009 Stracker TH, Usui T, Petrini JH. Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response. Dna Repair. 8: 1047-54. PMID 19473886 DOI: 10.1016/j.dnarep.2009.04.012  0.352
2009 Adelman CA, Petrini JH. Division of labor: DNA repair and the cell cycle specific functions of the Mre11 complex. Cell Cycle (Georgetown, Tex.). 8: 1510-4. PMID 19395852 DOI: 10.4161/Cc.8.10.8380  0.736
2009 Petrini JH. DNA replication reaches the breaking point. Cell. 137: 211-2. PMID 19379688 DOI: 10.1016/j.cell.2009.04.003  0.375
2009 Deriano L, Stracker TH, Baker A, Petrini JH, Roth DB. Roles for NBS1 in alternative nonhomologous end-joining of V(D)J recombination intermediates. Molecular Cell. 34: 13-25. PMID 19362533 DOI: 10.1016/j.molcel.2009.03.009  0.438
2009 Usui T, Foster SS, Petrini JH. Maintenance of the DNA-damage checkpoint requires DNA-damage-induced mediator protein oligomerization. Molecular Cell. 33: 147-59. PMID 19187758 DOI: 10.1016/j.molcel.2008.12.022  0.401
2009 Shull ER, Lee Y, Nakane H, Stracker TH, Zhao J, Russell HR, Petrini JH, McKinnon PJ. Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS. Genes & Development. 23: 171-80. PMID 19171781 DOI: 10.1101/gad.1746609  0.428
2009 Stracker TH, Williams BR, Deriano L, Theunissen JW, Adelman CA, Roth DB, Petrini JH. Artemis and nonhomologous end joining-independent influence of DNA-dependent protein kinase catalytic subunit on chromosome stability. Molecular and Cellular Biology. 29: 503-14. PMID 19015239 DOI: 10.1128/Mcb.01354-08  0.729
2009 Adelman CA, De S, Petrini JH. Rad50 is dispensable for the maintenance and viability of postmitotic tissues. Molecular and Cellular Biology. 29: 483-92. PMID 19001091 DOI: 10.1128/Mcb.01525-08  0.734
2008 Stracker TH, Petrini JH. Working together and apart: the twisted relationship of the Mre11 complex and Chk2 in apoptosis and tumor suppression. Cell Cycle (Georgetown, Tex.). 7: 3618-21. PMID 19029802 DOI: 10.4161/cc.7.23.7064  0.401
2008 Stracker TH, Couto SS, Cordon-Cardo C, Matos T, Petrini JH. Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage. Molecular Cell. 31: 21-32. PMID 18614044 DOI: 10.1016/j.molcel.2008.04.028  0.535
2008 Morales M, Liu Y, Laiakis EC, Morgan WF, Nimer SD, Petrini JH. DNA damage signaling in hematopoietic cells: a role for Mre11 complex repair of topoisomerase lesions. Cancer Research. 68: 2186-93. PMID 18381424 DOI: 10.1158/0008-5472.Can-07-2355  0.454
2008 Adelman CA, Petrini JH. ZIP4H (TEX11) deficiency in the mouse impairs meiotic double strand break repair and the regulation of crossing over. Plos Genetics. 4: e1000042. PMID 18369460 DOI: 10.1371/Journal.Pgen.1000042  0.728
2008 Kim HS, Vijayakumar S, Reger M, Harrison JC, Haber JE, Weil C, Petrini JH. Functional interactions between Sae2 and the Mre11 complex. Genetics. 178: 711-23. PMID 18245357 DOI: 10.1534/Genetics.107.081331  0.465
2007 Stracker TH, Morales M, Couto SS, Hussein H, Petrini JH. The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex. Nature. 447: 218-21. PMID 17429352 DOI: 10.1038/nature05740  0.463
2007 Krishna S, Wagener BM, Liu HP, Lo YC, Sterk R, Petrini JH, Nickoloff JA. Mre11 and Ku regulation of double-strand break repair by gene conversion and break-induced replication. Dna Repair. 6: 797-808. PMID 17321803 DOI: 10.1016/J.Dnarep.2007.01.006  0.434
2007 Usui T, Petrini JH. The Saccharomyces cerevisiae 14-3-3 proteins Bmh1 and Bmh2 directly influence the DNA damage-dependent functions of Rad53. Proceedings of the National Academy of Sciences of the United States of America. 104: 2797-802. PMID 17299042 DOI: 10.1073/pnas.0611259104  0.372
2007 Cherry SM, Adelman CA, Theunissen JW, Hassold TJ, Hunt PA, Petrini JH. The Mre11 complex influences DNA repair, synapsis, and crossing over in murine meiosis. Current Biology : Cb. 17: 373-8. PMID 17291760 DOI: 10.1016/J.Cub.2006.12.048  0.735
2006 Usui T, Petrini JH, Morales M. Rad50S alleles of the Mre11 complex: questions answered and questions raised. Experimental Cell Research. 312: 2694-9. PMID 16857186 DOI: 10.1016/j.yexcr.2006.06.013  0.364
2006 Theunissen JW, Petrini JH. Methods for studying the cellular response to DNA damage: influence of the Mre11 complex on chromosome metabolism. Methods in Enzymology. 409: 251-84. PMID 16793406 DOI: 10.1016/S0076-6879(05)09015-4  0.331
2006 Heikkinen K, Rapakko K, Karppinen SM, Erkko H, Knuutila S, Lundán T, Mannermaa A, Børresen-Dale AL, Borg A, Barkardottir RB, Petrini J, Winqvist R. RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability. Carcinogenesis. 27: 1593-9. PMID 16474176 DOI: 10.1093/Carcin/Bgi360  0.364
2006 Adelman CA, Petrini JH, Attwooll CL. Modeling disease in the mouse: lessons from DNA damage response and cell cycle control genes. Journal of Cellular Biochemistry. 97: 459-73. PMID 16288461 DOI: 10.1002/Jcb.20701  0.655
2005 Morales M, Theunissen JW, Kim CF, Kitagawa R, Kastan MB, Petrini JH. The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor. Genes & Development. 19: 3043-54. PMID 16357220 DOI: 10.1101/Gad.1373705  0.462
2005 Levran O, Attwooll C, Henry RT, Milton KL, Neveling K, Rio P, Batish SD, Kalb R, Velleuer E, Barral S, Ott J, Petrini J, Schindler D, Hanenberg H, Auerbach AD. The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia. Nature Genetics. 37: 931-3. PMID 16116424 DOI: 10.1038/Ng1624  0.435
2005 Chiolo I, Carotenuto W, Maffioletti G, Petrini JH, Foiani M, Liberi G. Srs2 and Sgs1 DNA helicases associate with Mre11 in different subcomplexes following checkpoint activation and CDK1-mediated Srs2 phosphorylation. Molecular and Cellular Biology. 25: 5738-51. PMID 15964827 DOI: 10.1128/Mcb.25.13.5738-5751.2005  0.497
2005 Levran O, Attwooll C, Henry RT, Milton KL, Neveling K, Rio P, Batish SD, Kalb R, Velleuer E, Barral S, Ott J, Petrini J, Schindler D, Hanenberg H, Auerbach AD. Addendum: The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia Nature Genetics. 37: 1296-1296. DOI: 10.1038/Ng1105-1296  0.308
2004 Shroff R, Arbel-Eden A, Pilch D, Ira G, Bonner WM, Petrini JH, Haber JE, Lichten M. Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break Current Biology. 14: 1703-1711. PMID 15458641 DOI: 10.1016/J.Cub.2004.09.047  0.397
2004 Karlseder J, Hoke K, Mirzoeva OK, Bakkenist C, Kastan MB, Petrini JH, de Lange T. The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response. Plos Biology. 2: E240. PMID 15314656 DOI: 10.1371/Journal.Pbio.0020240  0.425
2004 Stracker TH, Theunissen JW, Morales M, Petrini JH. The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together. Dna Repair. 3: 845-54. PMID 15279769 DOI: 10.1016/J.Dnarep.2004.03.014  0.474
2004 Petrini JH, Theunissen JW. Double strand break metabolism and cancer susceptibility: lessons from the mre11 complex. Cell Cycle (Georgetown, Tex.). 3: 541-2. PMID 15034299 DOI: 10.4161/Cc.3.5.835  0.413
2004 Borde V, Lin W, Novikov E, Petrini JH, Lichten M, Nicolas A. Association of Mre11p with double-strand break sites during yeast meiosis. Molecular Cell. 13: 389-401. PMID 14967146 DOI: 10.1016/S1097-2765(04)00034-6  0.443
2003 Theunissen JW, Kaplan MI, Hunt PA, Williams BR, Ferguson DO, Alt FW, Petrini JH. Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice. Molecular Cell. 12: 1511-23. PMID 14690604 DOI: 10.1016/S1097-2765(03)00455-6  0.398
2003 Petrini JH, Stracker TH. The cellular response to DNA double-strand breaks: defining the sensors and mediators. Trends in Cell Biology. 13: 458-62. PMID 12946624  0.344
2003 Mirzoeva OK, Petrini JH. DNA replication-dependent nuclear dynamics of the Mre11 complex. Molecular Cancer Research : McR. 1: 207-18. PMID 12556560  0.414
2002 Lee SE, Bressan DA, Petrini JH, Haber JE. Complementation between N-terminal Saccharomyces cerevisiae mre11 alleles in DNA repair and telomere length maintenance. Dna Repair. 1: 27-40. PMID 12509295 DOI: 10.1016/S1568-7864(01)00003-9  0.424
2002 Bender CF, Sikes ML, Sullivan R, Huye LE, Le Beau MM, Roth DB, Mirzoeva OK, Oltz EM, Petrini JH. Cancer predisposition and hematopoietic failure in Rad50(S/S) mice. Genes & Development. 16: 2237-51. PMID 12208847 DOI: 10.1101/Gad.1007902  0.369
2002 Hopfner KP, Craig L, Moncalian G, Zinkel RA, Usui T, Owen BA, Karcher A, Henderson B, Bodmer JL, McMurray CT, Carney JP, Petrini JH, Tainer JA. The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair. Nature. 418: 562-6. PMID 12152085 DOI: 10.1038/Nature00922  0.377
2002 Williams BR, Mirzoeva OK, Morgan WF, Lin J, Dunnick W, Petrini JH. A murine model of Nijmegen breakage syndrome. Current Biology : Cb. 12: 648-53. PMID 11967151 DOI: 10.1016/S0960-9822(02)00763-7  0.455
2002 Falck J, Petrini JH, Williams BR, Lukas J, Bartek J. The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways. Nature Genetics. 30: 290-4. PMID 11850621 DOI: 10.1038/Ng845  0.457
2001 Maser RS, Zinkel R, Petrini JH. An alternative mode of translation permits production of a variant NBS1 protein from the common Nijmegen breakage syndrome allele. Nature Genetics. 27: 417-21. PMID 11279524 DOI: 10.1038/86920  0.38
2001 Mirzoeva OK, Petrini JHJ. DNA Damage-Dependent Nuclear Dynamics of the Mre11 Complex Molecular and Cellular Biology. 21: 1898-1898. DOI: 10.1128/mcb.21.5.1898-1898.2001  0.37
2000 Zhu XD, Küster B, Mann M, Petrini JH, de Lange T. Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres. Nature Genetics. 25: 347-52. PMID 10888888 DOI: 10.1038/77139  0.433
2000 Petrini JH. The Mre11 complex and ATM: collaborating to navigate S phase. Current Opinion in Cell Biology. 12: 293-6. PMID 10801460 DOI: 10.1016/S0955-0674(00)00091-0  0.474
1999 Luo G, Yao MS, Bender CF, Mills M, Bladl AR, Bradley A, Petrini JH. Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation. Proceedings of the National Academy of Sciences of the United States of America. 96: 7376-81. PMID 10377422 DOI: 10.1073/Pnas.96.13.7376  0.491
1999 Petrini JH. The mammalian Mre11-Rad50-nbs1 protein complex: integration of functions in the cellular DNA-damage response. American Journal of Human Genetics. 64: 1264-9. PMID 10205255 DOI: 10.1086/302391  0.423
1997 Petrini JH, Bressan DA, Yao MS. The RAD52 epistasis group in mammalian double strand break repair. Seminars in Immunology. 9: 181-8. PMID 9200329 DOI: 10.1006/Smim.1997.0067  0.414
1997 Yao MS, Bladl AR, Petrini JH. 22 Functional analysis of the protein complex through targeted disruption of the murine RAD50 genomic locus: Implications for DNA double strand break repair. An astro research fellowship presentation International Journal of Radiation Oncology*Biology*Physics. 39: 145. DOI: 10.1016/S0360-3016(97)80579-2  0.432
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