Donald J. Vander Griend, Ph.D. - Publications

Affiliations: 
2004 University of Chicago, Chicago, IL 
Area:
Oncology, Molecular Biology

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Vellky JE, Kirkpatrick BJ, Gutgesell LC, Morales M, Brown RM, Wu Y, Maienschein-Cline M, Notardonato LD, Weinfeld MS, Nguyen RH, Brister E, Sverdlov M, Liu L, Xu Z, Kregel S, ... ... Vander Griend DJ, et al. ERBB3 overexpression is enriched in diverse patient populations with castration-sensitive prostate cancer and is associated with a unique AR activity signature. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 38306015 DOI: 10.1158/1078-0432.CCR-23-2161  0.362
2023 Rather HA, Almousa S, Kumar A, Sharma M, Pennington I, Kim S, Su Y, He Y, Ghara AR, Sai KKS, Navone NM, Vander Griend DJ, Deep G. The β-Secretase 1 Enzyme as a Novel Therapeutic Target for Prostate Cancer. Cancers. 16. PMID 38201438 DOI: 10.3390/cancers16010010  0.375
2023 Bennett L, Jaiswal PK, Harkless RV, Long TM, Gao N, Vandenburg B, Selman P, Durdana I, Lastra RR, Vander Griend D, Adelaiye-Ogala R, Szmulewitz RZ, Conzen SD. Glucocorticoid receptor (GR) activation is associated with increased cAMP/PKA signaling in castrate-resistant prostate cancer. Molecular Cancer Therapeutics. PMID 38030378 DOI: 10.1158/1535-7163.MCT-22-0479  0.452
2023 Vellky JE, Wu Y, Moline D, Drnevich J, Maienschein-Cline M, Valyi-Nagy K, Kajdacsy-Balla A, Vander Griend DJ. Single-cell RNA sequencing of human prostate basal epithelial cells reveals zone-specific cellular populations and gene expression signatures. The Journal of Pathology. PMID 37984408 DOI: 10.1002/path.6227  0.338
2023 Williams A, Gutgesell L, de Wet L, Selman P, Dey A, Avineni M, Kapoor I, Mendez M, Brown R, Lamperis S, Blajszczak C, Bueter E, Kregel S, Vander Griend DJ, Szmulewitz R. SOX expression in prostate cancer drives resistance to nuclear hormone receptor signaling inhibition through the WEE1/CDK1 signaling axis. Cancer Letters. 216209. PMID 37169162 DOI: 10.1016/j.canlet.2023.216209  0.43
2022 Moline DC, Zenner ML, Burr A, Vellky JE, Nonn L, Vander Griend DJ. Single-cell RNA-Seq identifies factors necessary for the regenerative phenotype of prostate luminal epithelial progenitors. American Journal of Clinical and Experimental Urology. 10: 425-439. PMID 36636696  0.311
2022 Deng S, Wang C, Wang Y, Xu Y, Li X, Johnson NA, Mukherji A, Lo UG, Xu L, Gonzalez J, Metang LA, Ye J, Tirado CR, Rodarte K, Zhou Y, ... ... Vander Griend DJ, et al. Ectopic JAK-STAT activation enables the transition to a stem-like and multilineage state conferring AR-targeted therapy resistance. Nature Cancer. PMID 36065066 DOI: 10.1038/s43018-022-00431-9  0.333
2022 de Wet L, Williams A, Gillard M, Kregel S, Lamperis S, Gutgesell LC, Vellky JE, Brown R, Conger K, Paner GP, Wang H, Platz EA, De Marzo AM, Mu P, Coloff JL, ... ... Vander Griend DJ, et al. Correction to: SOX2 mediates metabolic reprogramming of prostate cancer cells. Oncogene. 41: 1234. PMID 35145235 DOI: 10.1038/s41388-022-02228-7  0.345
2022 de Wet L, Williams A, Gillard M, Kregel S, Lamperis S, Gutgesell LC, Vellky JE, Brown R, Conger K, Paner GP, Wang H, Platz EE, De Marzo AM, Mu P, Coloff JL, ... ... Vander Griend DJ, et al. SOX2 mediates metabolic reprogramming of prostate cancer cells. Oncogene. PMID 35067686 DOI: 10.1038/s41388-021-02157-x  0.454
2020 Hintz HM, Gallant JP, Vander Griend DJ, Coleman I, Nelson PS, LeBeau AM. Imaging Fibroblast Activation Protein Alpha improves diagnosis of metastatic Prostate Cancer with Positron Emission Tomography. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32636317 DOI: 10.1158/1078-0432.Ccr-20-1358  0.354
2020 VanOpstall C, Perike S, Brechka H, Gillard M, Lamperis S, Zhu B, Brown R, Bhanvadia R, Vander Griend DJ. MEIS-mediated suppression of human prostate cancer growth and metastasis through HOXB13-dependent regulation of proteoglycans. Elife. 9. PMID 32553107 DOI: 10.7554/Elife.53600  0.485
2019 Peak TC, Panigrahi GK, Praharaj PP, Su Y, Shi L, Chyr J, Rivera-Chávez J, Flores-Bocanegra L, Singh R, Vander Griend DJ, Oberlies NH, Kerr BA, Hemal A, Bitting RL, Deep G. Syntaxin 6-mediated exosome secretion regulates enzalutamide resistance in prostate cancer. Molecular Carcinogenesis. PMID 31674708 DOI: 10.1002/Mc.23129  0.341
2019 Shapovalova M, Lee JK, Li Y, Vander Griend DJ, Coleman I, Nelson PS, Dehm SM, LeBeau AM. PEG10 promoter-driven expression of reporter genes enables molecular imaging of lethal prostate cancer. Cancer Research. PMID 31530569 DOI: 10.1158/0008-5472.Can-19-2181  0.39
2019 Madueke I, Hu WY, Hu D, Swanson SM, Vander Griend D, Abern M, Prins GS. The role of WNT10B in normal prostate gland development and prostate cancer. The Prostate. PMID 31433503 DOI: 10.1002/pros.23894  0.346
2019 Hu WY, Xu L, Chen B, Ou S, Muzzarelli KM, Hu DP, Li Y, Yang Z, Vander Griend DJ, Prins GS, Qin Z. Targeting prostate cancer cells with enzalutamide-HDAC inhibitor hybrid drug 2-75. The Prostate. PMID 31135075 DOI: 10.1002/pros.23832  0.394
2019 McAuley E, Moline D, VanOpstall C, Lamperis S, Brown R, Vander Griend DJ. Sox2 Expression Marks Castration-Resistant Progenitor Cells in the Adult Murine Prostate. Stem Cells (Dayton, Ohio). PMID 30720908 DOI: 10.1002/Stem.2987  0.339
2018 Bhanvadia RR, VanOpstall C, Brechka H, Barashi NS, Gillard M, McAuley EM, Apiz J, Paner GP, Chan WC, Andrade J, Demarzo A, Han M, Szmulewitz RZ, Vander Griend DJ. MEIS1 and MEIS2 Expression and Prostate Cancer Progression: A Role For HOXB13 Binding Partners in Metastatic Disease. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29716922 DOI: 10.1158/1078-0432.CCR-17-3673  0.372
2018 Peak TC, Praharaj P, Panigrahi GK, Doyle M, Su Y, Schlaepfer IR, Singh R, Vander Griend DJ, Alickson J, Hemal A, Atala A, Deep G. Exosomes secreted by placental stem cells selectively inhibit growth of aggressive prostate cancer cells. Biochemical and Biophysical Research Communications. PMID 29627574 DOI: 10.1016/J.Bbrc.2018.04.038  0.416
2017 Gillard M, Lack J, Pontier A, Gandla D, Hatcher D, Sowalsky AG, Rodriguez-Nieves J, Vander Griend D, Paner G, VanderWeele D. Integrative Genomic Analysis of Coincident Cancer Foci Implicates CTNNB1 and PTEN Alterations in Ductal Prostate Cancer. European Urology Focus. PMID 29229583 DOI: 10.1016/J.Euf.2017.12.003  0.337
2017 Brechka H, Bhanvadia RR, VanOpstall C, Vander Griend DJ. HOXB13 mutations and binding partners in prostate development and cancer: Function, clinical significance, and future directions. Genes & Diseases. 4: 75-87. PMID 28798948 DOI: 10.1016/j.gendis.2017.01.003  0.42
2017 Urbanucci A, Barfeld SJ, Kytölä V, Itkonen HM, Coleman IM, Vodák D, Sjöblom L, Sheng X, Tolonen T, Minner S, Burdelski C, Kivinummi KK, Kohvakka A, Kregel S, Takhar M, ... ... Vander Griend DJ, et al. Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer. Cell Reports. 19: 2045-2059. PMID 28591577 DOI: 10.1016/J.Celrep.2017.05.049  0.392
2017 Bhanvadia R, McAuley E, Chan W, Brechka H, Paner G, Vander Griend D. MP87-04 MEIS PROTEINS AS PREDICTIVE MARKERS OF METASTATIC PROSTATE CANCER PROGRESSION Journal of Urology. 197. DOI: 10.1016/j.juro.2017.02.2708  0.387
2016 Brechka H, McAuley EM, Lamperis SM, Paner GP, Vander Griend DJ. Contribution of Caudal Müllerian Duct Mesenchyme to Prostate Development. Stem Cells and Development. PMID 27595922 DOI: 10.1089/scd.2016.0088  0.31
2016 Kregel S, Chen JL, Tom W, Krishnan V, Kach J, Brechka H, Fessenden TB, Isikbay M, Paner GP, Szmulewitz RZ, Vander Griend DJ. Acquired resistance to the second-generation androgen receptor antagonist enzalutamide in castration-resistant prostate cancer. Oncotarget. PMID 27036029 DOI: 10.18632/Oncotarget.8456  0.335
2014 Reyes EE, VanderWeele DJ, Isikbay M, Duggan R, Campanile A, Stadler WM, Vander Griend DJ, Szmulewitz RZ. Quantitative characterization of androgen receptor protein expression and cellular localization in circulating tumor cells from patients with metastatic castration-resistant prostate cancer. Journal of Translational Medicine. 12: 313. PMID 25424879 DOI: 10.1186/S12967-014-0313-Z  0.762
2014 Kregel S, Szmulewitz RZ, Vander Griend DJ. The pluripotency factor Nanog is directly upregulated by the androgen receptor in prostate cancer cells. The Prostate. 74: 1530-43. PMID 25175748 DOI: 10.1002/pros.22870  0.424
2014 Vander Griend DJ, Litvinov IV, Isaacs JT. Conversion of androgen receptor signaling from a growth suppressor in normal prostate epithelial cells to an oncogene in prostate cancer cells involves a gain of function in c-Myc regulation. International Journal of Biological Sciences. 10: 627-42. PMID 24948876 DOI: 10.7150/Ijbs.8756  0.403
2014 Isikbay M, Otto K, Kregel S, Kach J, Cai Y, Vander Griend DJ, Conzen SD, Szmulewitz RZ. Glucocorticoid receptor activity contributes to resistance to androgen-targeted therapy in prostate cancer. Hormones & Cancer. 5: 72-89. PMID 24615402 DOI: 10.1007/S12672-014-0173-2  0.429
2013 Cai Y, Kregel S, Vander Griend DJ. Formation of human prostate epithelium using tissue recombination of rodent urogenital sinus mesenchyme and human stem cells. Journal of Visualized Experiments : Jove. PMID 23852031 DOI: 10.3791/50327  0.34
2013 Zeng Y, Wodzenski D, Gao D, Shiraishi T, Terada N, Li Y, Vander Griend DJ, Luo J, Kong C, Getzenberg RH, Kulkarni P. Stress-response protein RBM3 attenuates the stem-like properties of prostate cancer cells by interfering with CD44 variant splicing. Cancer Research. 73: 4123-33. PMID 23667174 DOI: 10.1158/0008-5472.Can-12-1343  0.396
2013 Kregel S, Kiriluk KJ, Rosen AM, Cai Y, Reyes EE, Otto KB, Tom W, Paner GP, Szmulewitz RZ, Vander Griend DJ. Sox2 is an androgen receptor-repressed gene that promotes castration-resistant prostate cancer. Plos One. 8: e53701. PMID 23326489 DOI: 10.1371/Journal.Pone.0053701  0.756
2013 Reyes EE, Kunovac SK, Duggan R, Kregel S, Vander Griend DJ. Growth kinetics of CD133-positive prostate cancer cells. The Prostate. 73: 724-33. PMID 23138940 DOI: 10.1002/Pros.22616  0.735
2012 Chen JL, Otto K, Vander Griend D. Role of homeobox pathway in prostate carcinogenesis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 126. PMID 27968195 DOI: 10.1200/jco.2012.30.5_suppl.126  0.381
2012 Chen JL, Li J, Kiriluk KJ, Rosen AM, Paner GP, Antic T, Lussier YA, Vander Griend DJ. Deregulation of a Hox protein regulatory network spanning prostate cancer initiation and progression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 4291-302. PMID 22723371 DOI: 10.1158/1078-0432.Ccr-12-0373  0.424
2011 Knopeke MT, Ritschdorff ET, Clark R, Vander Griend DJ, Khan S, Thobe M, Shear JB, Rinker-Schaeffer CW. Building on the foundation of daring hypotheses: using the MKK4 metastasis suppressor to develop models of dormancy and metastatic colonization. Febs Letters. 585: 3159-65. PMID 21925502 DOI: 10.1016/J.Febslet.2011.09.007  0.752
2010 D'Antonio JM, Vander Griend DJ, Antony L, Ndikuyeze G, Dalrymple SL, Koochekpour S, Isaacs JT. Loss of androgen receptor-dependent growth suppression by prostate cancer cells can occur independently from acquiring oncogenic addiction to androgen receptor signaling. Plos One. 5: e11475. PMID 20628607 DOI: 10.1371/Journal.Pone.0011475  0.405
2010 Vander Griend DJ, D'Antonio J, Gurel B, Antony L, Demarzo AM, Isaacs JT. Cell-autonomous intracellular androgen receptor signaling drives the growth of human prostate cancer initiating cells. The Prostate. 70: 90-9. PMID 19790235 DOI: 10.1002/Pros.21043  0.419
2009 Vander Griend DJ, Antony L, Dalrymple SL, Xu Y, Christensen SB, Denmeade SR, Isaacs JT. Amino acid containing thapsigargin analogues deplete androgen receptor protein via synthesis inhibition and induce the death of prostate cancer cells. Molecular Cancer Therapeutics. 8: 1340-9. PMID 19417145 DOI: 10.1158/1535-7163.Mct-08-1136  0.381
2009 D'Antonio JM, Vander Griend DJ, Isaacs JT. DNA licensing as a novel androgen receptor mediated therapeutic target for prostate cancer. Endocrine-Related Cancer. 16: 325-32. PMID 19240183 DOI: 10.1677/Erc-08-0205  0.355
2008 Vander Griend DJ, Karthaus WL, Dalrymple S, Meeker A, DeMarzo AM, Isaacs JT. The role of CD133 in normal human prostate stem cells and malignant cancer-initiating cells. Cancer Research. 68: 9703-11. PMID 19047148 DOI: 10.1158/0008-5472.Can-08-3084  0.356
2007 Vander Griend DJ, Litvinov IV, Isaacs JT. Stabilizing androgen receptor in mitosis inhibits prostate cancer proliferation. Cell Cycle (Georgetown, Tex.). 6: 647-51. PMID 17387277 DOI: 10.4161/Cc.6.6.4028  0.41
2006 Litvinov IV, Vander Griend DJ, Antony L, Dalrymple S, De Marzo AM, Drake CG, Isaacs JT. Androgen receptor as a licensing factor for DNA replication in androgen-sensitive prostate cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 15085-90. PMID 17015840 DOI: 10.1073/Pnas.0603057103  0.393
2006 Litvinov IV, Vander Griend DJ, Xu Y, Antony L, Dalrymple SL, Isaacs JT. Low-calcium serum-free defined medium selects for growth of normal prostatic epithelial stem cells. Cancer Research. 66: 8598-607. PMID 16951173 DOI: 10.1158/0008-5472.Can-06-1228  0.304
2006 Hickson JA, Huo D, Vander Griend DJ, Lin A, Rinker-Schaeffer CW, Yamada SD. The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma Cancer Research. 66: 2264-2270. PMID 16489030 DOI: 10.1158/0008-5472.Can-05-3676  0.782
2005 Vander Griend DJ, Kocherginsky M, Hickson JA, Stadler WM, Lin A, Rinker-Schaeffer CW. Suppression of metastatic colonization by the context-dependent activation of the c-Jun NH2-terminal kinase kinases JNKK1/MKK4 and MKK7 Cancer Research. 65: 10984-10991. PMID 16322247 DOI: 10.1158/0008-5472.Can-05-2382  0.777
2005 Berger JC, Vander Griend DJ, Robinson VL, Hickson JA, Rinker-Schaeffer CW. Metastasis suppressor genes: from gene identification to protein function and regulation. Cancer Biology & Therapy. 4: 805-12. PMID 16082183 DOI: 10.4161/Cbt.4.8.1865  0.773
2004 Berger JC, Vander Griend D, Stadler WM, Rinker-Schaeffer C. Metastasis suppressor genes: signal transduction, cross-talk and the potential for modulating the behavior of metastatic cells. Anti-Cancer Drugs. 15: 559-68. PMID 15205597 DOI: 10.1097/01.Cad.0000132233.36512.Fa  0.755
2004 Vander Griend DJ, Berger JC, Rinker-Schaeffer CW. Suppression of metastasis--a new function for known proteins. Journal of the National Cancer Institute. 96: 344-5. PMID 14996848 DOI: 10.1093/JNCI/DJH078  0.649
2004 Vander Griend DJ, Rinker-Schaeffer CW. A new look at an old problem: the survival and organ-specific growth of metastases. Science's Stke : Signal Transduction Knowledge Environment. 2004: pe3. PMID 14734785 DOI: 10.1126/stke.2162004pe3  0.706
2003 Robinson VL, Hickson JA, Vander Griend DJ, Dubauskas Z, Rinker-Schaeffer CW. MKK4 and metastasis suppression: a marriage of signal transduction and metastasis research. Clinical & Experimental Metastasis. 20: 25-30. PMID 12650604 DOI: 10.1023/A:1022586318678  0.762
2002 Yamada SD, Hickson JA, Hrobowski Y, Vander Griend DJ, Benson D, Montag A, Karrison T, Huo D, Rutgers J, Adams S, Rinker-Schaeffer CW. Mitogen-activated protein kinase kinase 4 (MKK4) acts as a metastasis suppressor gene in human ovarian carcinoma Cancer Research. 62: 6717-6723. PMID 12438272  0.784
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