Kathryn L. Schwertfeger - Publications

Affiliations: 
Molecular, Cellular, Developmental Biology and Genetics University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Cell Biology, Molecular Biology

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Tarullo SE, He Y, Daughters C, Knutson TP, Henzler CM, Price MA, Shanley R, Witschen P, Tolg C, Kaspar RE, Hallstrom C, Gittsovich L, Sulciner ML, Zhang X, Forster CL, ... ... Schwertfeger KL, et al. Receptor for hyaluronan-mediated motility (RHAMM) defines an invasive niche associated with tumor progression and predicts poor outcomes in breast cancer patients. The Journal of Pathology. PMID 37186300 DOI: 10.1002/path.6082  0.46
2023 Bapat AS, O'Connor CH, Schwertfeger KL. Targeting the NF-κB pathway enhances responsiveness of mammary tumors to JAK inhibitors. Scientific Reports. 13: 5349. PMID 37005447 DOI: 10.1038/s41598-023-32321-0  0.417
2023 Witschen PM, Elfstrum AK, Nelson AC, Schwertfeger KL. Characterization of Hyaluronan Localization in the Developing Mammary Gland and Mammary Tumors. Journal of Mammary Gland Biology and Neoplasia. 28: 1. PMID 36723776 DOI: 10.1007/s10911-023-09528-y  0.397
2021 Jesser EA, Brady NJ, Huggins DN, Witschen PM, O'Connor CH, Schwertfeger KL. STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment. Breast Cancer Research : Bcr. 23: 104. PMID 34743736 DOI: 10.1186/s13058-021-01481-0  0.458
2021 Huggins DN, LaRue RS, Wang Y, Knutson TP, Xu Y, Williams JW, Schwertfeger KL. Characterizing macrophage diversity in metastasis-bearing lungs reveals a lipid-associated macrophage subset. Cancer Research. PMID 34389631 DOI: 10.1158/0008-5472.CAN-21-0101  0.323
2020 Ibrahim AM, Moss MA, Gray Z, Rojo MD, Burke CM, Schwertfeger KL, Dos Santos CO, Machado HL. Diverse Macrophage Populations Contribute to the Inflammatory Microenvironment in Premalignant Lesions During Localized Invasion. Frontiers in Oncology. 10: 569985. PMID 33072601 DOI: 10.3389/fonc.2020.569985  0.344
2020 Witschen PM, Chaffee TS, Brady NJ, Huggins DN, Knutson TP, LaRue RS, Munro SA, Tiegs L, McCarthy JB, Nelson AC, Schwertfeger KL. Erratum: Witschen, P.M., et al. Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer. 2020, , 1325. Cancers. 12. PMID 32977674 DOI: 10.3390/cancers12102736  0.339
2020 Wang Y, Chaffee TS, LaRue RS, Huggins DN, Witschen PM, Ibrahim AM, Nelson AC, Machado HL, Schwertfeger KL. Tissue resident macrophages promote extracellular matrix homeostasis in the mammary gland stroma of nulliparous mice. Elife. 9. PMID 32479261 DOI: 10.7554/Elife.57438  0.414
2020 Witschen PM, Chaffee TS, Brady NJ, Huggins DN, Knutson TP, LaRue RS, Munro SA, Tiegs L, McCarthy JB, Nelson AC, Schwertfeger KL. Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer. Cancers. 12. PMID 32455980 DOI: 10.3390/Cancers12051325  0.492
2020 Wang Y, Chaffee TS, LaRue RS, Huggins DN, Witschen PM, Ibrahim AM, Nelson AC, Machado HL, Schwertfeger KL. Author response: Tissue-resident macrophages promote extracellular matrix homeostasis in the mammary gland stroma of nulliparous mice Elife. DOI: 10.7554/Elife.57438.Sa2  0.342
2019 Brian BF, Jolicoeur AS, Guerrero CR, Nunez MG, Sychev ZE, Hegre SA, Sætrom P, Habib N, Drake JM, Schwertfeger KL, Freedman TS. Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells. Elife. 8. PMID 31282857 DOI: 10.7554/Elife.46043  0.418
2019 Irey EA, Lassiter CM, Brady NJ, Chuntova P, Wang Y, Knutson TP, Henzler C, Chaffee TS, Vogel RI, Nelson AC, Farrar MA, Schwertfeger KL. JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors. Proceedings of the National Academy of Sciences of the United States of America. PMID 31147469 DOI: 10.1073/Pnas.1816410116  0.483
2019 Leon-Cabrera S, Schwertfeger KL, Terrazas LI. Inflammation as a Target in Cancer Therapy Mediators of Inflammation. 2019: 1971698. PMID 30983878 DOI: 10.1155/2019/1971698  0.31
2019 Brian BF, Jolicoeur AS, Guerrero CR, Nunez MG, Sychev ZE, Hegre SA, Sætrom P, Habib N, Drake JM, Schwertfeger KL, Freedman TS. Author response: Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells Elife. DOI: 10.7554/Elife.46043.050  0.342
2018 Nelson AC, Machado HL, Schwertfeger KL. Breaking through to the Other Side: Microenvironment Contributions to DCIS Initiation and Progression. Journal of Mammary Gland Biology and Neoplasia. PMID 30168075 DOI: 10.1007/S10911-018-9409-Z  0.461
2018 Regan Anderson TM, Ma S, Perez Kerkvliet C, Peng Y, Helle TM, Krutilina RI, Raj GV, Cidlowski JA, Ostrander JH, Schwertfeger KL, Seagroves TN, Lange CA. Taxol Induces Brk-dependent Pro-survival Phenotypes in TNBC Cells through an AhR/GR/HIF-driven Signaling Axis. Molecular Cancer Research : McR. PMID 29991529 DOI: 10.1158/1541-7786.Mcr-18-0410  0.51
2018 Doak GR, Schwertfeger KL, Wood DK. Distant Relations: Macrophage Functions in the Metastatic Niche. Trends in Cancer. 4: 445-459. PMID 29860988 DOI: 10.1016/J.Trecan.2018.03.011  0.469
2018 Truong TH, Hu H, Temiz NA, Hagen K, Girard BJ, Brady NJ, Schwertfeger KL, Lange CA, Ostrander JH. Cancer Stem Cell Phenotypes in ER+ Breast Cancer Models are Promoted by PELP1/AIB1 Complexes. Molecular Cancer Research : McR. PMID 29348189 DOI: 10.1158/1541-7786.Mcr-17-0598  0.557
2017 Aukes K, Forsman C, Brady NJ, Astleford K, Blixt N, Sachdev D, Jensen ED, Mansky KC, Schwertfeger KL. Breast cancer cell-derived fibroblast growth factors enhance osteoclast activity and contribute to the formation of metastatic lesions. Plos One. 12: e0185736. PMID 28968431 DOI: 10.1371/Journal.Pone.0185736  0.532
2017 Brady NJ, Farrar MA, Schwertfeger KL. STAT5 deletion in macrophages alters ductal elongation and branching during mammary gland development. Developmental Biology. PMID 28606561 DOI: 10.1016/J.Ydbio.2017.06.007  0.453
2017 Knutson TP, Truong TH, Ma S, Brady NJ, Sullivan ME, Raj G, Schwertfeger KL, Lange CA. Posttranslationally modified progesterone receptors direct ligand-specific expression of breast cancer stem cell-associated gene programs. Journal of Hematology & Oncology. 10: 89. PMID 28412963 DOI: 10.1186/S13045-017-0462-7  0.439
2016 Girard BJ, Knutson TP, Kuker B, McDowell L, Schwertfeger KL, Ostrander JH. Cytoplasmic Localization of Proline, Glutamic Acid, Leucine Rich Protein 1 (PELP1) Induces Breast Epithelial Cell Migration through Upregulation of Inhibitor of kappa B Kinase Epsilon and Inflammatory Crosstalk with Macrophages. The Journal of Biological Chemistry. PMID 27881676 DOI: 10.1074/Jbc.M116.739847  0.526
2016 Bohrer LR, Chaffee TS, Chuntova P, Brady NJ, Witschen PM, Kemp SE, Nelson AC, Walcheck B, Schwertfeger KL. ADAM17 in tumor associated leukocytes regulates inflammatory mediators and promotes mammary tumor formation. Genes & Cancer. 7: 240-253. PMID 27738494 DOI: 10.18632/Genesandcancer.115  0.498
2016 Brady NJ, Chuntova P, Schwertfeger KL. Macrophages: Regulators of the Inflammatory Microenvironment during Mammary Gland Development and Breast Cancer. Mediators of Inflammation. 2016: 4549676. PMID 26884646 DOI: 10.1155/2016/4549676  0.497
2016 Brady NJ, Farrar MA, Schwertfeger KL. Abstract B64: Macrophage-specific deletion of STAT5 disrupts normal mammary gland development and accelerates mammary tumorigenesis Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Advbc15-B64  0.582
2015 Brincks EL, Kucaba TA, James BR, Murphy KA, Schwertfeger KL, Sangwan V, Banerjee S, Saluja AK, Griffith TS. Triptolide Enhances the Tumoricidal Activity of TRAIL Against Renal Cell Carcinoma. The Febs Journal. PMID 26426449 DOI: 10.1111/Febs.13532  0.403
2015 Farooqui M, Bohrer LR, Brady NJ, Chuntova P, Kemp SE, Wardwell CT, Nelson AC, Schwertfeger KL. Epiregulin contributes to breast tumorigenesis through regulating matrix metalloproteinase 1 and promoting cell survival. Molecular Cancer. 14: 138. PMID 26215578 DOI: 10.1186/S12943-015-0408-Z  0.465
2015 Schwertfeger KL, Cowman MK, Telmer PG, Turley EA, McCarthy JB. Hyaluronan, Inflammation, and Breast Cancer Progression. Frontiers in Immunology. 6: 236. PMID 26106384 DOI: 10.3389/Fimmu.2015.00236  0.534
2015 Avdulov S, Herrera J, Smith K, Peterson M, Gomez-Garcia JR, Beadnell TC, Schwertfeger KL, Benyumov AO, Manivel JC, Li S, Bielinsky AK, Yee D, Bitterman PB, Polunovsky VA. eIF4E threshold levels differ in governing normal and neoplastic expansion of mammary stem and luminal progenitor cells. Cancer Research. 75: 687-97. PMID 25524901 DOI: 10.1158/0008-5472.Can-14-2571  0.407
2015 Brady NJ, Farrar MA, Schwertfeger KL. Abstract S4-01: Macrophage-specific deletion of STAT5 disrupts normal mammary gland development and accelerates mammary tumorigenesis Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-S4-01  0.579
2015 Schwertfeger KL, Farooqui M, Bohrer LR, Nelson AC. Abstract P4-06-01: Epiregulin-induced matrix metalloproteinase-1 contributes to early stages of breast tumorigenesis Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P4-06-01  0.534
2015 Bohrer LR, Chuntova P, McCarthy JB, Schwertfeger KL. Abstract B84: Activation of the STAT3 pathway leads to a hyaluronan-rich microenvironment that promotes breast cancer growth and therapeutic resistance Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-B84  0.537
2015 Barcelo H, Brady NJ, Schwertfeger KL, Gross M, Thyagarajan B. Abstract 2771: Neutrophil specific mitochondrial DNA copy number as a biomarker for breast cancer Epidemiology. 75: 2771-2771. DOI: 10.1158/1538-7445.Am2015-2771  0.354
2014 Tseng YY, Moriarity BS, Gong W, Akiyama R, Tiwari A, Kawakami H, Ronning P, Reuland B, Guenther K, Beadnell TC, Essig J, Otto GM, O'Sullivan MG, Largaespada DA, Schwertfeger KL, et al. PVT1 dependence in cancer with MYC copy-number increase. Nature. 512: 82-6. PMID 25043044 DOI: 10.1038/Nature13311  0.344
2014 Klos KS, Warmka JK, Drachenberg DM, Chang L, Luxton GW, Leung CT, Schwertfeger KL, Wattenberg EV. Building bridges toward invasion: tumor promoter treatment induces a novel protein kinase C-dependent phenotype in MCF10A mammary cell acini. Plos One. 9: e90722. PMID 24599099 DOI: 10.1371/Journal.Pone.0090722  0.478
2014 Bohrer LR, Chuntova P, Bade LK, Beadnell TC, Leon RP, Brady NJ, Ryu Y, Goldberg JE, Schmechel SC, Koopmeiners JS, McCarthy JB, Schwertfeger KL. Activation of the FGFR-STAT3 pathway in breast cancer cells induces a hyaluronan-rich microenvironment that licenses tumor formation. Cancer Research. 74: 374-86. PMID 24197137 DOI: 10.1158/0008-5472.Can-13-2469  0.558
2013 Brady N, Chuntova P, Bade LK, Schwertfeger KL. The FGF/FGFR axis as a therapeutic target in breast cancer. Expert Review of Endocrinology & Metabolism. 8: 391-402. PMID 25400686 DOI: 10.1586/17446651.2013.811910  0.482
2013 Forsman CL, Ng BC, Heinze RK, Kuo C, Sergi C, Gopalakrishnan R, Yee D, Graf D, Schwertfeger KL, Petryk A. BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization Developmental Biology. 373: 95-106. PMID 23103586 DOI: 10.1016/J.Ydbio.2012.10.007  0.404
2013 Chuntova P, Bohrer L, Bade L, Schwertfeger K. Abstract A37: Activation of FGFR1 signaling in mammary tumors leads to STAT3 activation and chemoresistance Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-A37  0.497
2012 Reed JR, Stone MD, Beadnell TC, Ryu Y, Griffin TJ, Schwertfeger KL. Fibroblast growth factor receptor 1 activation in mammary tumor cells promotes macrophage recruitment in a CX3CL1-dependent manner. Plos One. 7: e45877. PMID 23029290 DOI: 10.1371/Journal.Pone.0045877  0.567
2012 Bohrer LR, Schwertfeger KL. Macrophages promote fibroblast growth factor receptor-driven tumor cell migration and invasion in a CXCR2-dependent manner. Molecular Cancer Research : McR. 10: 1294-305. PMID 22893608 DOI: 10.1158/1541-7786.Mcr-12-0275  0.55
2012 Tseng Y, Beadnell T, Schwertfeger K, Bagchi A. Abstract 3288: A chromosome engineering mouse model to identify mechanisms by which duplication of 8q24 promotes human breast cancer Cancer Research. 72: 3288-3288. DOI: 10.1158/1538-7445.Am2012-3288  0.455
2011 Lofgren KA, Ostrander JH, Housa D, Hubbard GK, Locatelli A, Bliss RL, Schwertfeger KL, Lange CA. Mammary gland specific expression of Brk/PTK6 promotes delayed involution and tumor formation associated with activation of p38 MAPK. Breast Cancer Research : Bcr. 13: R89. PMID 21923922 DOI: 10.1186/Bcr2946  0.527
2011 Bade LK, Goldberg JE, Dehut HA, Hall MK, Schwertfeger KL. Mammary tumorigenesis induced by fibroblast growth factor receptor 1 requires activation of the epidermal growth factor receptor. Journal of Cell Science. 124: 3106-17. PMID 21868365 DOI: 10.1242/Jcs.082651  0.435
2011 Dressing GE, Goldberg JE, Charles NJ, Schwertfeger KL, Lange CA. Membrane progesterone receptor expression in mammalian tissues: a review of regulation and physiological implications. Steroids. 76: 11-7. PMID 20869977 DOI: 10.1016/J.Steroids.2010.09.006  0.4
2010 Reed JR, Schwertfeger KL. Immune cell location and function during post-natal mammary gland development. Journal of Mammary Gland Biology and Neoplasia. 15: 329-39. PMID 20730636 DOI: 10.1007/S10911-010-9188-7  0.376
2010 Goldberg JE, Schwertfeger KL. Proinflammatory cytokines in breast cancer: mechanisms of action and potential targets for therapeutics. Current Drug Targets. 11: 1133-46. PMID 20545607 DOI: 10.2174/138945010792006799  0.466
2010 Pond AC, Herschkowitz JI, Schwertfeger KL, Welm B, Zhang Y, York B, Cardiff RD, Hilsenbeck S, Perou CM, Creighton CJ, Lloyd RE, Rosen JM. Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer. Cancer Research. 70: 4868-79. PMID 20501844 DOI: 10.1158/0008-5472.Can-09-4404  0.496
2010 Tseng Y, Schwertfeger KL, Bagchi A. Abstract 3272: Chromosome engineered mouse model for human 8q24 amplicon observed in breast cancer patients Cancer Research. 70: 3272-3272. DOI: 10.1158/1538-7445.Am10-3272  0.453
2009 Schwertfeger KL. Fibroblast growth factors in development and cancer: insights from the mammary and prostate glands. Current Drug Targets. 10: 632-44. PMID 19601767 DOI: 10.2174/138945009788680419  0.441
2009 Reed JR, Leon RP, Hall MK, Schwertfeger KL. Interleukin-1beta and fibroblast growth factor receptor 1 cooperate to induce cyclooxygenase-2 during early mammary tumourigenesis. Breast Cancer Research : Bcr. 11: R21. PMID 19393083 DOI: 10.1186/Bcr2246  0.471
2007 Xian W, Schwertfeger KL, Rosen JM. Distinct roles of fibroblast growth factor receptor 1 and 2 in regulating cell survival and epithelial-mesenchymal transition. Molecular Endocrinology (Baltimore, Md.). 21: 987-1000. PMID 17284663 DOI: 10.1210/Me.2006-0518  0.446
2006 Schwertfeger KL, Rosen JM, Cohen DA. Mammary gland macrophages: pleiotropic functions in mammary development. Journal of Mammary Gland Biology and Neoplasia. 11: 229-38. PMID 17115264 DOI: 10.1007/S10911-006-9028-Y  0.421
2006 Limesand KH, Schwertfeger KL, Anderson SM. MDM2 is required for suppression of apoptosis by activated Akt1 in salivary acinar cells. Molecular and Cellular Biology. 26: 8840-56. PMID 16982679 DOI: 10.1128/Mcb.01846-05  0.358
2006 Schwertfeger KL, Xian W, Kaplan AM, Burnett SH, Cohen DA, Rosen JM. A critical role for the inflammatory response in a mouse model of preneoplastic progression. Cancer Research. 66: 5676-85. PMID 16740705 DOI: 10.1158/0008-5472.Can-05-3781  0.502
2005 Xian W, Schwertfeger KL, Vargo-Gogola T, Rosen JM. Pleiotropic effects of FGFR1 on cell proliferation, survival, and migration in a 3D mammary epithelial cell model. The Journal of Cell Biology. 171: 663-73. PMID 16301332 DOI: 10.1083/Jcb.200505098  0.428
2003 Schwertfeger KL, McManaman JL, Palmer CA, Neville MC, Anderson SM. Expression of constitutively activated Akt in the mammary gland leads to excess lipid synthesis during pregnancy and lactation. Journal of Lipid Research. 44: 1100-12. PMID 12700340 DOI: 10.1194/Jlr.M300045-Jlr200  0.353
2001 Schwertfeger KL, Richert MM, Anderson SM. Mammary gland involution is delayed by activated Akt in transgenic mice. Molecular Endocrinology (Baltimore, Md.). 15: 867-81. PMID 11376107 DOI: 10.1210/Mend.15.6.0663  0.4
2000 Richert MM, Schwertfeger KL, Ryder JW, Anderson SM. An atlas of mouse mammary gland development. Journal of Mammary Gland Biology and Neoplasia. 5: 227-41. PMID 11149575 DOI: 10.1023/A:1026499523505  0.333
2000 Schwertfeger KL, Hunter S, Heasley LE, Levresse V, Leon RP, DeGregori J, Anderson SM. Prolactin stimulates activation of c-jun N-terminal kinase (JNK). Molecular Endocrinology (Baltimore, Md.). 14: 1592-602. PMID 11043575 DOI: 10.1210/Mend.14.10.0536  0.355
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