Pengbo Zhou - Publications

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 
Area:
Molecular Biology

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zhou P, Yan F. CRL4 Ubiquitin Pathway and DNA Damage Response. Advances in Experimental Medicine and Biology. 1217: 225-239. PMID 31898231 DOI: 10.1007/978-981-15-1025-0_14  0.433
2017 Robu M, Shah RG, Purohit NK, Zhou P, Naegeli H, Shah GM. Poly(ADP-ribose) polymerase 1 escorts XPC to UV-induced DNA lesions during nucleotide excision repair. Proceedings of the National Academy of Sciences of the United States of America. PMID 28760956 DOI: 10.1073/Pnas.1706981114  0.376
2016 Jia L, Yan F, Cao W, Chen Z, Zheng H, Li H, Pan Y, Narula N, Ren X, Li H, Zhou P. Dysregulation of CUL4A and CUL4B Ubiquitin Ligases in Lung Cancer. The Journal of Biological Chemistry. PMID 27974468 DOI: 10.1074/Jbc.M116.765230  0.367
2016 Yin Y, Liu L, Yang C, Lin C, Veith GM, Wang C, Sutovsky P, Zhou P, Ma L. Cell autonomous and non-autonomous function of CUL4B in Mouse Spermatogenesis. The Journal of Biological Chemistry. PMID 26846852 DOI: 10.1074/Jbc.M115.699660  0.325
2015 Hannah J, Zhou P. Distinct and overlapping functions of the cullin E3 ligase scaffolding proteins CUL4A and CUL4B. Gene. 573: 33-45. PMID 26344709 DOI: 10.1016/J.Gene.2015.08.064  0.766
2015 Hannah J, Zhou P. Methods: A small-molecule SMASh hit. Nature Chemical Biology. 11: 637-8. PMID 26284670 DOI: 10.1038/Nchembio.1886  0.749
2015 Li Q, Li Y, Gu B, Fang L, Zhou P, Bao S, Huang L, Dai X. Akt Phosphorylates Wnt Coactivator and Chromatin Effector Pygo2 at Serine 48 to Antagonize Its Ubiquitin/Proteasome-Mediated Degradation. The Journal of Biological Chemistry. PMID 26170450 DOI: 10.1074/Jbc.M115.639419  0.37
2015 Yang C, Boyson CA, Di Liberto M, Huang X, Hannah J, Dorn DC, Moore MA, Chen-Kiang S, Zhou P. CDK4/6 Inhibitor PD 0332991 Sensitizes Acute Myeloid Leukemia to Cytarabine-Mediated Cytotoxicity. Cancer Research. 75: 1838-45. PMID 25744718 DOI: 10.1158/0008-5472.Can-14-2486  0.742
2015 Barbieri CE, Boysen G, Prandi D, Chae S, Dahiya A, Nataraj S, Blattner M, Marotz C, Xu L, Huang J, Lecca P, Chhangawala S, Zhou P, Sboner A, Demichelis F, et al. Abstract NG01: SPOP mutation is associated with genomic instability in prostate cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Ng01  0.325
2015 Hannah J, Zhou P. Methods: A small-molecule SMASh hit Nature Chemical Biology. 11: 637-638. DOI: 10.1038/nchembio.1886  0.71
2014 Fattah FJ, Hara K, Fattah KR, Yang C, Wu N, Warrington R, Chen DJ, Zhou P, Boothman DA, Yu H. The transcription factor TFII-I promotes DNA translesion synthesis and genomic stability. Plos Genetics. 10: e1004419. PMID 24922507 DOI: 10.1371/Journal.Pgen.1004419  0.403
2014 D'Alfonso TM, Hannah J, Chen Z, Liu Y, Zhou P, Shin SJ. Axl receptor tyrosine kinase expression in breast cancer. Journal of Clinical Pathology. 67: 690-6. PMID 24904064 DOI: 10.1136/Jclinpath-2013-202161  0.722
2013 Zhang S, Zhao H, Darzynkiewicz Z, Zhou P, Zhang Z, Lee EY, Lee MY. A novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phase. The Journal of Biological Chemistry. 288: 29550-61. PMID 23913683 DOI: 10.1074/Jbc.M113.490466  0.422
2013 Hannah J, Zhou PB. The CUL4A ubiquitin ligase is a potential therapeutic target in skin cancer and other malignancies. Chinese Journal of Cancer. 32: 478-82. PMID 23845142 DOI: 10.5732/Cjc.012.10279  0.773
2013 Geng C, He B, Xu L, Barbieri CE, Eedunuri VK, Chew SA, Zimmermann M, Bond R, Shou J, Li C, Blattner M, Lonard DM, Demichelis F, Coarfa C, Rubin MA, ... Zhou P, et al. Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover. Proceedings of the National Academy of Sciences of the United States of America. 110: 6997-7002. PMID 23559371 DOI: 10.1073/Pnas.1304502110  0.373
2013 Lee J, Shieh JH, Zhang J, Liu L, Zhang Y, Eom JY, Morrone G, Moore MA, Zhou P. Improved ex vivo expansion of adult hematopoietic stem cells by overcoming CUL4-mediated degradation of HOXB4. Blood. 121: 4082-9. PMID 23520338 DOI: 10.1182/Blood-2012-09-455204  0.346
2013 Kong F, Zhang J, Li Y, Hao X, Ren X, Li H, Zhou P. Engineering a single ubiquitin ligase for the selective degradation of all activated ErbB receptor tyrosine kinases. Oncogene. 33: 986-95. PMID 23416973 DOI: 10.1038/Onc.2013.33  0.377
2013 Malatesta M, Peschiaroli A, Memmi EM, Zhang J, Antonov A, Green DR, Barlev NA, Garabadgiu AV, Zhou P, Melino G, Bernassola F. The Cul4A–DDB1 E3 ubiquitin ligase complex represses p73 transcriptional activity Oncogene. 32: 4721-4726. PMID 23085759 DOI: 10.1038/Onc.2012.463  0.393
2012 Lee J, Zhou P. Pathogenic Role of the CRL4 Ubiquitin Ligase in Human Disease. Frontiers in Oncology. 2: 21. PMID 22649780 DOI: 10.3389/Fonc.2012.00021  0.347
2012 Liu L, Yin Y, Li Y, Prevedel L, Lacy EH, Ma L, Zhou P. Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis. Cell Research. 22: 1258-69. PMID 22453236 DOI: 10.1038/Cr.2012.48  0.316
2012 Lee J, Shieh J, Zhang J, Liu L, Morrone G, Moore MAS, Zhou P. Abstract 211: Ubiquitin-proteolytic regulation of hematopoietic stem cell expansion Cancer Research. 72: 211-211. DOI: 10.1158/1538-7445.Am2012-211  0.361
2011 Cooper J, Li W, You L, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO, Long SB, Erdjument-Bromage H, Zhou P, Tempst P, Giancotti FG. Merlin/NF2 functions upstream of the nuclear E3 ubiquitin ligase CRL4DCAF1 to suppress oncogenic gene expression. Science Signaling. 4: pt6. PMID 21878678 DOI: 10.1126/Scisignal.2002314  0.346
2011 Yin Y, Lin C, Kim ST, Roig I, Chen H, Liu L, Veith GM, Jin RU, Keeney S, Jasin M, Moley K, Zhou P, Ma L. The E3 ubiquitin ligase Cullin 4A regulates meiotic progression in mouse spermatogenesis. Developmental Biology. 356: 51-62. PMID 21624359 DOI: 10.1016/J.Ydbio.2011.05.661  0.429
2011 Hannah J, Zhou P. Maximizing target protein ablation by integration of RNAi and protein knockout. Cell Research. 21: 1152-4. PMID 21606956 DOI: 10.1038/Cr.2011.89  0.734
2011 Funasaka T, Nakano H, Wu Y, Hashizume C, Gu L, Nakamura T, Wang W, Zhou P, Moore MA, Sato H, Wong RW. RNA export factor RAE1 contributes to NUP98-HOXA9-mediated leukemogenesis. Cell Cycle (Georgetown, Tex.). 10: 1456-67. PMID 21467841 DOI: 10.4161/Cc.10.9.15494  0.317
2010 Lee J, Zhou P. Cullins and cancer. Genes & Cancer. 1: 690-9. PMID 21127736 DOI: 10.1177/1947601910382899  0.321
2010 Liu L, Lee J, Zhou P. Navigating the nucleotide excision repair threshold. Journal of Cellular Physiology. 224: 585-9. PMID 20458729 DOI: 10.1002/Jcp.22205  0.419
2010 Li W, You L, Cooper J, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO, Long SB, Erdjument-Bromage H, Zhou P, Tempst P, Giancotti FG. Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus. Cell. 140: 477-90. PMID 20178741 DOI: 10.1016/J.Cell.2010.01.029  0.312
2010 Zhou P, Lee J, Zhang J, Liu L, Shieh J, Moore MAS. Abstract 1157: Ubiquitin-proteolytic control of HOX homeodomain proteins in normal and malignant hematopoiesis Cancer Research. 70: 1157-1157. DOI: 10.1158/1538-7445.Am10-1157  0.401
2009 Liu L, Lee S, Zhang J, Peters SB, Hannah J, Zhang Y, Yin Y, Koff A, Ma L, Zhou P. CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis. Molecular Cell. 34: 451-60. PMID 19481525 DOI: 10.1016/J.Molcel.2009.04.020  0.754
2009 Hannah J, Zhou P. Regulation of DNA damage response pathways by the cullin-RING ubiquitin ligases. Dna Repair. 8: 536-43. PMID 19231300 DOI: 10.1016/J.Dnarep.2009.01.011  0.759
2007 Lee J, Zhou P. DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase. Molecular Cell. 26: 775-80. PMID 17588513 DOI: 10.1016/J.Molcel.2007.06.001  0.384
2007 Moore MA, Chung KY, Plasilova M, Schuringa JJ, Shieh JH, Zhou P, Morrone G. NUP98 dysregulation in myeloid leukemogenesis. Annals of the New York Academy of Sciences. 1106: 114-42. PMID 17442773 DOI: 10.1196/Annals.1392.019  0.328
2007 Cang Y, Zhang J, Nicholas SA, Kim AL, Zhou P, Goff SP. DDB1 is essential for genomic stability in developing epidermis. Proceedings of the National Academy of Sciences of the United States of America. 104: 2733-7. PMID 17301228 DOI: 10.1073/Pnas.0611311104  0.389
2006 Chung KY, Morrone G, Schuringa JJ, Plasilova M, Shieh JH, Zhang Y, Zhou P, Moore MA. Enforced expression of NUP98-HOXA9 in human CD34(+) cells enhances stem cell proliferation. Cancer Research. 66: 11781-91. PMID 17178874 DOI: 10.1158/0008-5472.Can-06-0706  0.373
2006 Cang Y, Zhang J, Nicholas SA, Bastien J, Li B, Zhou P, Goff SP. Deletion of DDB1 in mouse brain and lens leads to p53-dependent elimination of proliferating cells. Cell. 127: 929-40. PMID 17129780 DOI: 10.1016/J.Cell.2006.09.045  0.395
2006 Chen X, Zhang J, Lee J, Lin PS, Ford JM, Zheng N, Zhou P. A kinase-independent function of c-Abl in promoting proteolytic destruction of damaged DNA binding proteins. Molecular Cell. 22: 489-99. PMID 16713579 DOI: 10.1016/J.Molcel.2006.04.021  0.431
2006 Zhou P. REGgamma: a shortcut to destruction. Cell. 124: 256-7. PMID 16439199 DOI: 10.1016/J.Cell.2006.01.003  0.327
2006 Li T, Chen X, Garbutt KC, Zhou P, Zheng N. Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase. Cell. 124: 105-17. PMID 16413485 DOI: 10.1016/J.Cell.2005.10.033  0.313
2005 Zhang J, Zhou P. Ectopic targeting of substrates to the ubiquitin pathway. Methods in Enzymology. 399: 823-33. PMID 16338397 DOI: 10.1016/S0076-6879(05)99053-8  0.385
2005 Zhou P. Targeted protein degradation. Current Opinion in Chemical Biology. 9: 51-5. PMID 15701453 DOI: 10.1016/J.Cbpa.2004.10.012  0.424
2005 Plasilova M, Chung K, Shieh JH, Fields RJ, Morrone G, Chadburn A, Knowles DM, Zhou P, Moore MA. Depletion of NUP98: A Common Leukemogenetic Mechanism in AML? Blood. 106: 667-667. DOI: 10.1182/Blood.V106.11.667.667  0.352
2004 Zhou P. Determining protein half-lives. Methods in Molecular Biology (Clifton, N.J.). 284: 67-77. PMID 15173609 DOI: 10.1385/1-59259-816-1:067  0.347
2004 Cohen JC, Scott D, Miller J, Zhang J, Zhou P, Larson JE. Transient in utero knockout (TIUKO) of C-MYC affects late lung and intestinal development in the mouse Bmc Developmental Biology. 4. PMID 15090077 DOI: 10.1186/1471-213X-4-4  0.306
2003 Zhang Y, Morrone G, Zhang J, Chen X, Lu X, Ma L, Moore M, Zhou P. CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein. The Embo Journal. 22: 6057-67. PMID 14609952 DOI: 10.1093/Emboj/Cdg577  0.341
2003 Zhang J, Zheng N, Zhou P. Exploring the functional complexity of cellular proteins by protein knockout. Proceedings of the National Academy of Sciences of the United States of America. 100: 14127-32. PMID 14593203 DOI: 10.1073/Pnas.2233012100  0.361
2003 Cong F, Zhang J, Pao W, Zhou P, Varmus H. A protein knockdown strategy to study the function of β-catenin in tumorigenesis Bmc Molecular Biology. 4. PMID 14516475 DOI: 10.1186/1471-2199-4-10  0.319
2001 Chen X, Zhang Y, Douglas L, Zhou P. UV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradation. The Journal of Biological Chemistry. 276: 48175-82. PMID 11673459 DOI: 10.1074/Jbc.M106808200  0.363
2000 Zhou P, Bogacki R, McReynolds L, Howley PM. Harnessing the ubiquitination machinery to target the degradation of specific cellular proteins. Molecular Cell. 6: 751-6. PMID 11030355 DOI: 10.1016/S1097-2765(00)00074-5  0.413
2000 Kleijnen MF, Shih AH, Zhou P, Kumar S, Soccio RE, Kedersha NL, Gill G, Howley PM. The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome Molecular Cell. 6: 409-419. PMID 10983987 DOI: 10.1016/S1097-2765(00)00040-X  0.364
1998 Zhou P, Howley PM. Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases. Molecular Cell. 2: 571-80. PMID 9844630 DOI: 10.1016/S1097-2765(00)80156-2  0.342
1998 Patrick GN, Zhou P, Kwon YT, Howley PM, Tsai LH. p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway. The Journal of Biological Chemistry. 273: 24057-64. PMID 9727024 DOI: 10.1074/Jbc.273.37.24057  0.315
1995 Zhou P, Byrne C, Jacobs J, Fuchs E. Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate. Genes & Development. 9: 700-13. PMID 7537238 DOI: 10.1101/Gad.9.6.700  0.323
1994 Zhou P, Szczypka MS, Young R, Thiele DJ. A system for gene cloning and manipulation in the yeast Candida glabrata Gene. 142: 135-140. PMID 8181748 DOI: 10.1016/0378-1119(94)90368-9  0.573
1993 Zhou P, Thiele DJ. Rapid transcriptional autoregulation of a yeast metalloregulatory transcription factor is essential for nigh-level copper detoxification Genes and Development. 7: 1824-1835. PMID 8370529 DOI: 10.1101/Gad.7.9.1824  0.581
1993 Zhou P, Koch KA, Thiele DJ. Transcriptional regulation and function of yeast metallothioneins Journal of Inorganic Biochemistry. 51: 578. DOI: 10.1016/0162-0134(93)85600-D  0.585
1992 Zhou P, Szczypka MS, Sosinowski T, Thiele DJ. Expression of a yeast metallothionein gene family is activated by a single metalloregulatory transcription factor. Molecular and Cellular Biology. 12: 3766-75. PMID 1508182 DOI: 10.1128/Mcb.12.9.3766  0.615
1991 Zhou P, Thiele DJ. Isolation of a metal-activated transcription factor gene from Candida glabrata by complementation in Saccharomyces cerevisiae Proceedings of the National Academy of Sciences of the United States of America. 88: 6112-6116. PMID 2068090 DOI: 10.1073/Pnas.88.14.6112  0.612
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