Barbara Vanderhyden - Publications

Affiliations: 
Cellular and Molecular Medicine University of Ottawa, Ottawa, ON, Canada 
Area:
Oncology, Pathology, Molecular Biology

90 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Rodriguez GM, Yakubovich E, Murshed H, Maranda V, Galpin KJC, Cudmore A, Hanna AMR, Macdonald E, Ramesh S, Garson K, Vanderhyden BC. NLRC5 overexpression in ovarian tumors remodels the tumor microenvironment and increases T-cell reactivity toward autologous tumor-associated antigens. Frontiers in Immunology. 14: 1295208. PMID 38235131 DOI: 10.3389/fimmu.2023.1295208  0.387
2024 Galpin KJC, Rodriguez GM, Maranda V, Cook DP, Macdonald E, Murshed H, Zhao S, McCloskey CW, Chruscinski A, Levy GA, Ardolino M, Vanderhyden BC. FGL2 promotes tumour growth and attenuates infiltration of activated immune cells in melanoma and ovarian cancer models. Scientific Reports. 14: 787. PMID 38191799 DOI: 10.1038/s41598-024-51217-1  0.38
2023 Yakubovich E, Cook DP, Rodriguez GM, Vanderhyden BC. Mesenchymal ovarian cancer cells promote CD8 T cell exhaustion through the LGALS3-LAG3 axis. Npj Systems Biology and Applications. 9: 61. PMID 38086828 DOI: 10.1038/s41540-023-00322-4  0.404
2023 Rodriguez GM, Yakubovich E, Vanderhyden BC. Unveiling the Immunogenicity of Ovarian Tumors as the Crucial Catalyst for Therapeutic Success. Cancers. 15. PMID 38067396 DOI: 10.3390/cancers15235694  0.399
2023 Cook DP, Galpin KJC, Rodriguez GM, Shakfa N, Wilson-Sanchez J, Echaibi M, Pereira M, Matuszewska K, Haagsma J, Murshed H, Cudmore AO, MacDonald E, Tone A, Shepherd TG, Petrik JJ, ... ... Vanderhyden BC, et al. Comparative analysis of syngeneic mouse models of high-grade serous ovarian cancer. Communications Biology. 6: 1152. PMID 37957414 DOI: 10.1038/s42003-023-05529-z  0.34
2023 Wong B, Bergeron A, Maznyi G, Ng K, Jirovec A, Birdi HK, Serrano D, Spinelli M, Thomson M, Taha Z, Alwithenani A, Chen A, Lorimer I, Vanderhyden B, Arulanandam R, et al. Pevonedistat, a First in-class NEDD8-activating Enzyme Inhibitor, sensitizes cancer cells to VSVΔ51 Oncolytic Virotherapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 37766429 DOI: 10.1016/j.ymthe.2023.09.017  0.311
2023 Surendran A, Jamalkhah M, Poutou J, Birtch R, Lawson C, Dave J, Crupi MJF, Mayer J, Taylor V, Petryk J, de Souza CT, Moodie N, Billingsley JL, Austin B, Cormack N, ... ... Vanderhyden B, et al. Fatty acid transport protein inhibition sensitizes breast and ovarian cancers to oncolytic virus therapy lipid modulation of the tumor microenvironment. Frontiers in Immunology. 14: 1099459. PMID 36969187 DOI: 10.3389/fimmu.2023.1099459  0.325
2022 Rodriguez GM, Galpin KJC, Cook DP, Yakubovich E, Maranda V, Macdonald EA, Wilson-Sanchez J, Thomas AL, Burdette JE, Vanderhyden BC. The Tumor Immune Profile of Murine Ovarian Cancer Models: An Essential Tool For Ovarian Cancer Immunotherapy Research. Cancer Research Communications. 2: 417-433. PMID 36311166 DOI: 10.1158/2767-9764.crc-22-0017  0.414
2022 Alwosaibai K, Al-Hujaily EM, Alamri S, Ghandorah S, Garson K, Vanderhyden BC. PAX2 induces vascular-like structures in normal ovarian cells and ovarian cancer. Experimental and Therapeutic Medicine. 23: 412. PMID 35601066 DOI: 10.3892/etm.2022.11339  0.487
2022 Cook DP, Vanderhyden BC. Transcriptional census of epithelial-mesenchymal plasticity in cancer. Science Advances. 8: eabi7640. PMID 34985957 DOI: 10.1126/sciadv.abi7640  0.326
2021 David S, Plante A, Dallaire F, Tremblay JP, Sheehy G, Macdonald E, Forrest L, Daneshmand M, Trudel D, Wilson BC, Hopkins L, Murugkar S, Vanderhyden B, Leblond F. Multispectral label-free Raman spectroscopy can detect ovarian and endometrial cancer with high accuracy. Journal of Biophotonics. e202100198. PMID 34837331 DOI: 10.1002/jbio.202100198  0.344
2021 Alkailani M, Palidwor G, Poulin A, Mohan R, Pepin D, Vanderhyden B, Gibbings D. A genome-wide strategy to identify causes and consequences of retrotransposon expression finds activation by BRCA1 in ovarian cancer. Nar Cancer. 3: zcaa040. PMID 33447827 DOI: 10.1093/narcan/zcaa040  0.425
2020 Landry DA, Vaishnav HT, Vanderhyden BC. The significance of ovarian fibrosis. Oncotarget. 11: 4366-4370. PMID 33315987 DOI: 10.18632/oncotarget.27822  0.397
2020 Mehdi S, Macdonald E, Galpin K, Landry DA, Rodriguez G, Vanderhyden B, Bachvarov D. LY75 Suppression in Mesenchymal Epithelial Ovarian Cancer Cells Generates a Stable Hybrid EOC Cellular Phenotype, Associated with Enhanced Tumor Initiation, Spreading and Resistance to Treatment in Orthotopic Xenograft Mouse Model. International Journal of Molecular Sciences. 21. PMID 32679765 DOI: 10.3390/Ijms21144992  0.448
2020 Kim O, Park EY, Klinkebiel DL, Pack SD, Shin YH, Abdullaev Z, Emerson RE, Coffey DM, Kwon SY, Creighton CJ, Kwon S, Chang EC, Chiang T, Yatsenko AN, Chien J, ... ... Vanderhyden B, et al. In vivo modeling of metastatic human high-grade serous ovarian cancer in mice. Plos Genetics. 16: e1008808. PMID 32497036 DOI: 10.1371/Journal.Pgen.1008808  0.506
2020 Arulanandam R, Taha Z, Garcia V, Selman M, Chen A, Varette O, Jirovec A, Sutherland K, Macdonald E, Tzelepis F, Birdi H, Alluqmani N, Landry A, Bergeron A, Vanderhyden B, et al. The strategic combination of trastuzumab emtansine with oncolytic rhabdoviruses leads to therapeutic synergy. Communications Biology. 3: 254. PMID 32444806 DOI: 10.1038/s42003-020-0972-7  0.302
2020 Al-Zahrani KN, Abou-Hamad J, Cook DP, Pryce BR, Hodgins JJ, Labrèche C, Robineau-Charette P, de Souza CT, Bell JC, Auer RC, Ardolino M, Vanderhyden BC, Sabourin LA. Loss of the Ste20-like kinase induces a basal/stem-like phenotype in HER2-positive breast cancers. Oncogene. PMID 32393835 DOI: 10.1038/s41388-020-1315-3  0.358
2020 Feng Y, Tang Y, Mao Y, Liu Y, Yao D, Yang L, Garson K, Vanderhyden BC, Wang Q. PAX2 promotes epithelial ovarian cancer progression involving fatty acid metabolic reprogramming. International Journal of Oncology. PMID 31922217 DOI: 10.3892/Ijo.2020.4958  0.446
2020 Al-Zahrani KN, Abou-Hamad J, Pryce B, Cook DP, Hodgins J, Labreche C, Robineau-Charette P, Souza Cd, Bell J, Auer R, Ardolino M, Vanderhyden B, Schramek D, Sabourin L. Abstract P2-04-05: Loss of Ste20-like kinase induces a basal/stem-like phenotype in HER2-positive breast cancers Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P2-04-05  0.322
2019 McCloskey CW, Cook DP, Kelly BS, Azzi F, Allen CH, Forsyth-Greig A, Upham J, Rayner KJ, Gray DA, Boyd RW, Murugkar S, Lo B, Trudel D, Senterman MK, Vanderhyden BC. Metformin abrogates age-associated ovarian fibrosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31597663 DOI: 10.1158/1078-0432.Ccr-19-0603  0.349
2019 St-Jean G, Tsoi M, Abedini A, Levasseur A, Rico C, Morin M, Djordjevic B, Miinalainen I, Kaarteenaho R, Paquet M, Gévry N, Boyer A, Vanderhyden B, Boerboom D. and are required for the maintenance of multipotency in the Müllerian duct mesenchyme. Development (Cambridge, England). PMID 31575647 DOI: 10.1242/Dev.180430  0.335
2019 Cook DP, Vanderhyden BC. Ovarian cancer and the evolution of subtype classifications using transcriptional profiling. Biology of Reproduction. PMID 31187121 DOI: 10.1093/biolre/ioz099  0.443
2019 Sheta R, Bachvarova M, Macdonald E, Gobeil S, Vanderhyden B, Bachvarov D. The polypeptide GALNT6 Displays Redundant Functions upon Suppression of its Closest Homolog GALNT3 in Mediating Aberrant O-Glycosylation, Associated with Ovarian Cancer Progression. International Journal of Molecular Sciences. 20. PMID 31071912 DOI: 10.3390/Ijms20092264  0.48
2019 Xue Y, Meehan B, Macdonald E, Venneti S, Wang XQD, Witkowski L, Jelinic P, Kong T, Martinez D, Morin G, Firlit M, Abedini A, Johnson RM, Cencic R, Patibandla J, ... ... Vanderhyden B, et al. CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary. Nature Communications. 10: 558. PMID 30718512 DOI: 10.1038/S41467-018-06958-9  0.36
2018 Vuong NH, Cook DP, Forrest LA, Carter LE, Robineau-Charette P, Kofsky JM, Hodgkinson KM, Vanderhyden BC. Single-cell RNA-sequencing reveals transcriptional dynamics of estrogen-induced dysplasia in the ovarian surface epithelium. Plos Genetics. 14: e1007788. PMID 30418965 DOI: 10.1371/journal.pgen.1007788  0.434
2018 Al-Zahrani KN, Cook DP, Vanderhyden BC, Sabourin LA. Assessing the efficacy of androgen receptor and Sox10 as independent markers of the triple-negative breast cancer subtype by transcriptome profiling. Oncotarget. 9: 33348-33359. PMID 30279965 DOI: 10.18632/oncotarget.26072  0.334
2018 McCloskey CW, Rodriguez GM, Galpin KJC, Vanderhyden BC. Ovarian Cancer Immunotherapy: Preclinical Models and Emerging Therapeutics. Cancers. 10. PMID 30049987 DOI: 10.3390/cancers10080244  0.467
2018 Rodriguez GM, Galpin KJC, McCloskey CW, Vanderhyden BC. The Tumor Microenvironment of Epithelial Ovarian Cancer and Its Influence on Response to Immunotherapy. Cancers. 10. PMID 30042343 DOI: 10.3390/cancers10080242  0.465
2018 Hodgkinson K, Forrest LA, Vuong N, Garson K, Djordjevic B, Vanderhyden BC. GREB1 is an estrogen receptor-regulated tumour promoter that is frequently expressed in ovarian cancer. Oncogene. PMID 29973689 DOI: 10.1038/s41388-018-0377-y  0.506
2018 Hasim MS, Nessim C, Villeneuve PJ, Vanderhyden BC, Dimitroulakos J. Activating Transcription Factor 3 as a Novel Regulator of Chemotherapy Response in Breast Cancer. Translational Oncology. 11: 988-998. PMID 29940414 DOI: 10.1016/J.Tranon.2018.06.001  0.328
2018 Le Page C, Rahimi K, Köbel M, Tonin PN, Meunier L, Portelance L, Bernard M, Nelson BH, Bernardini MQ, Bartlett JMS, Bachvarov D, Gotlieb WH, Gilks B, McAlpine JN, Nachtigal MW, ... ... Vanderhyden B, et al. Characteristics and outcome of the COEUR Canadian validation cohort for ovarian cancer biomarkers. Bmc Cancer. 18: 347. PMID 29587661 DOI: 10.1186/S12885-018-4242-8  0.348
2017 Vuong NH, Salah Salah O, Vanderhyden BC. 17β-Estradiol sensitizes ovarian surface epithelium to transformation by suppressing Disabled-2 expression. Scientific Reports. 7: 16702. PMID 29196616 DOI: 10.1038/s41598-017-16219-2  0.508
2017 Sheta R, Wang ZQ, Bachvarova M, Plante M, Gregoire J, Renaud MC, Sebastianelli A, Gobeil S, Morin C, Macdonald E, Vanderhyden B, Bachvarov D. Hic-5 regulates epithelial to mesenchymal transition in ovarian cancer cells in a TGFβ1-independent manner. Oncotarget. 8: 82506-82530. PMID 29137281 DOI: 10.18632/Oncotarget.19714  0.49
2016 Moradi H, Ahmad A, Shepherdson D, Vuong NH, Niedbala G, Eapen L, Vanderhyden B, Nyiri B, Murugkar S. Raman micro-spectroscopy applied to treatment resistant and sensitive human ovarian cancer cells. Journal of Biophotonics. PMID 28009133 DOI: 10.1002/Jbio.201600211  0.397
2016 Köbel M, Rahimi K, Rambau PF, Naugler C, Le Page C, Meunier L, de Ladurantaye M, Lee S, Leung S, Goode EL, Ramus SJ, Carlson JW, Li X, Ewanowich CA, Kelemen LE, ... Vanderhyden B, et al. An Immunohistochemical Algorithm for Ovarian Carcinoma Typing. International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. PMID 26974996 DOI: 10.1097/Pgp.0000000000000274  0.377
2016 Bernaudo S, Salem M, Qi X, Zhou W, Zhang C, Yang W, Rosman D, Deng Z, Ye G, Yang B, Vanderhyden B, Wu Z, Peng C. Cyclin G2 inhibits epithelial-to-mesenchymal transition by disrupting Wnt/β-catenin signaling. Oncogene. PMID 26876206 DOI: 10.1038/Onc.2016.15  0.322
2016 Faddaoui A, Bachvarova M, Plante M, Gregoire J, Renaud MC, Sebastianelli A, Gobeil S, Morin C, Macdonald E, Vanderhyden B, Bachvarov D. The mannose receptor LY75 (DEC205/CD205) modulates cellular phenotype and metastatic potential of ovarian cancer cells. Oncotarget. 7: 14125-42. PMID 26871602 DOI: 10.18632/Oncotarget.7288  0.494
2015 Al-Hujaily EM, Tang Y, Yao DS, Carmona E, Garson K, Vanderhyden BC. Divergent roles of PAX2 in the etiology and progression of ovarian cancer. Cancer Prevention Research (Philadelphia, Pa.). PMID 26373819 DOI: 10.1158/1940-6207.CAPR-15-0121-T  0.48
2015 Wang ZQ, Faddaoui A, Bachvarova M, Plante M, Gregoire J, Renaud MC, Sebastianelli A, Guillemette C, Gobeil S, Macdonald E, Vanderhyden B, Bachvarov D. BCAT1 expression associates with ovarian cancer progression: possible implications in altered disease metabolism. Oncotarget. 6: 31522-43. PMID 26372729 DOI: 10.18632/Oncotarget.5159  0.55
2015 Barger CJ, Zhang W, Hillman J, Stablewski AB, Higgins MJ, Vanderhyden BC, Odunsi K, Karpf AR. Genetic determinants of FOXM1 overexpression in epithelial ovarian cancer and functional contribution to cell cycle progression. Oncotarget. 6: 27613-27. PMID 26243836 DOI: 10.18632/oncotarget.4546  0.48
2015 Eddie SL, Quartuccio SM, hAinmhire EÓ, Moyle-Heyrman G, Lantvit DD, Wei JJ, Vanderhyden BC, Burdette JE. Tumorigenesis and peritoneal colonization from fallopian tube epithelium. Oncotarget. PMID 25971410 DOI: 10.18632/Oncotarget.3985  0.394
2015 Arulanandam R, Batenchuk C, Varette O, Zakaria C, Garcia V, Forbes NE, Davis C, Krishnan R, Karmacharya R, Cox J, Sinha A, Babawy A, Waite K, Weinstein E, Falls T, ... ... Vanderhyden B, et al. Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing. Nature Communications. 6: 6410. PMID 25817275 DOI: 10.1038/Ncomms7410  0.441
2015 Ali AY, Kim JY, Pelletier JF, Vanderhyden BC, Bachvarov DR, Tsang BK. Akt confers cisplatin chemoresistance in human gynecological carcinoma cells by modulating PPM1D stability. Molecular Carcinogenesis. 54: 1301-14. PMID 25154814 DOI: 10.1002/mc.22205  0.398
2014 Hodgkinson KM, Vanderhyden BC. Consideration of GREB1 as a potential therapeutic target for hormone-responsive or endocrine-resistant cancers. Expert Opinion On Therapeutic Targets. 18: 1065-76. PMID 24998469 DOI: 10.1517/14728222.2014.936382  0.397
2014 McCloskey CW, Goldberg RL, Carter LE, Gamwell LF, Al-Hujaily EM, Collins O, Macdonald EA, Garson K, Daneshmand M, Carmona E, Vanderhyden BC. A new spontaneously transformed syngeneic model of high-grade serous ovarian cancer with a tumor-initiating cell population. Frontiers in Oncology. 4: 53. PMID 24672774 DOI: 10.3389/fonc.2014.00053  0.445
2014 Ribeiro JR, Lovasco LA, Vanderhyden BC, Freiman RN. Targeting TBP-Associated Factors in Ovarian Cancer. Frontiers in Oncology. 4: 45. PMID 24653979 DOI: 10.3389/Fonc.2014.00045  0.485
2014 Laviolette LA, Hodgkinson KM, Minhas N, Perez-Iratxeta C, Vanderhyden BC. 17β-estradiol upregulates GREB1 and accelerates ovarian tumor progression in vivo. International Journal of Cancer. Journal International Du Cancer. 135: 1072-84. PMID 24469735 DOI: 10.1002/Ijc.28741  0.785
2014 Ribeiro JR, Lovasco LA, Vanderhyden BC, Freiman RN. Targeting TBP-associated factors in ovarian cancer Frontiers in Oncology. 4. DOI: 10.3389/fonc.2014.00045  0.335
2014 Hodgkinson K, Laviolette L, Vanderhyden B. 322: Identification of GREB1 as a potential mediator of estrogen effects on ovarian cancer progression in a mouse model European Journal of Cancer. 50: S77. DOI: 10.1016/S0959-8049(14)50287-0  0.469
2013 Abdallah BY, Horne SD, Stevens JB, Liu G, Ying AY, Vanderhyden B, Krawetz SA, Gorelick R, Heng HH. Single cell heterogeneity: why unstable genomes are incompatible with average profiles. Cell Cycle (Georgetown, Tex.). 12: 3640-9. PMID 24091732 DOI: 10.4161/Cc.26580  0.37
2013 Wardell JR, Hodgkinson KM, Binder AK, Seymour KA, Korach KS, Vanderhyden BC, Freiman RN. Estrogen responsiveness of the TFIID subunit TAF4B in the normal mouse ovary and in ovarian tumors Biology of Reproduction. 89. PMID 24068106 DOI: 10.1095/Biolreprod.113.111336  0.49
2013 Gamwell LF, Gambaro K, Merziotis M, Crane C, Arcand SL, Bourada V, Davis C, Squire JA, Huntsman DG, Tonin PN, Vanderhyden BC. Small cell ovarian carcinoma: genomic stability and responsiveness to therapeutics. Orphanet Journal of Rare Diseases. 8: 33. PMID 23433318 DOI: 10.1186/1750-1172-8-33  0.37
2013 King SM, Quartuccio SM, Vanderhyden BC, Burdette JE. Early transformative changes in normal ovarian surface epithelium induced by oxidative stress require Akt upregulation, DNA damage and epithelial-stromal interaction. Carcinogenesis. 34: 1125-33. PMID 23299406 DOI: 10.1093/Carcin/Bgt003  0.321
2012 Garson K, Gamwell LF, Pitre EM, Vanderhyden BC. Technical challenges and limitations of current mouse models of ovarian cancer. Journal of Ovarian Research. 5: 39. PMID 23190474 DOI: 10.1186/1757-2215-5-39  0.345
2012 Parato KA, Breitbach CJ, Le Boeuf F, Wang J, Storbeck C, Ilkow C, Diallo JS, Falls T, Burns J, Garcia V, Kanji F, Evgin L, Hu K, Paradis F, Knowles S, ... ... Vanderhyden BC, et al. The oncolytic poxvirus JX-594 selectively replicates in and destroys cancer cells driven by genetic pathways commonly activated in cancers Molecular Therapy. 20: 749-758. PMID 22186794 DOI: 10.1038/mt.2011.276  0.402
2012 Aguirre MG, Chabot J, So R, Chaparro LES, Yan FJ, Garson K, Vanderhyden B, Sokoll KK. Abstract 2907: Novel liposomal compositions of PharmaGap's lead peptide: Effect on ovarian cancer cell proliferation and signaling pathways Cancer Research. 72: 2907-2907. DOI: 10.1158/1538-7445.Am2012-2907  0.412
2012 Vuong NH, Macdonald E, Hodgkinson K, Laviolette LA, Vanderhyden BC. Mechanisms by Which Estrogen Accelerates Ovarian Tumor Initiation. Biology of Reproduction. 87: 548-548. DOI: 10.1093/Biolreprod/87.S1.548  0.748
2012 Wardell JR, Hodgkinson K, Seymour KA, O'Brien CW, Vanderhyden BC, Freiman RN. TAF4b Is Induced by Estrogen in the Normal Mouse Ovary and During Estrogen-Supplemented Ovarian Tumorigenesis. Biology of Reproduction. 87: 536-536. DOI: 10.1093/Biolreprod/87.S1.536  0.365
2011 Pépin D, Shao ZQ, Huppé G, Wakefield A, Chu CW, Sharif Z, Vanderhyden BC. Kallikreins 5, 6 and 10 differentially alter pathophysiology and overall survival in an ovarian cancer xenograft model. Plos One. 6: e26075. PMID 22102857 DOI: 10.1371/journal.pone.0026075  0.475
2011 Laviolette LA, Ethier JF, Senterman MK, Devine PJ, Vanderhyden BC. Induction of a menopausal state alters the growth and histology of ovarian tumors in a mouse model of ovarian cancer. Menopause (New York, N.Y.). 18: 549-57. PMID 21221022 DOI: 10.1097/Gme.0B013E3181Fca1B6  0.783
2011 Hodgkinson KM, Laviolette L, Perez-Iratxeta C, Vanderhyden BC. Reproductive Steroid Hormones Alter Ovarian Cancer Progression in Mouse Models. Biology of Reproduction. 85: 343-343. DOI: 10.1093/Biolreprod/85.S1.343  0.778
2011 Vanderhyden BC, Laviolette L, Hodgkinson K, Garson K. Lessons Learned from Mouse Models of Ovarian Cancer. Biology of Reproduction. 85: 15-15. DOI: 10.1093/BIOLREPROD/85.S1.15  0.317
2010 Laviolette LA, Garson K, Macdonald EA, Senterman MK, Courville K, Crane CA, Vanderhyden BC. 17beta-estradiol accelerates tumor onset and decreases survival in a transgenic mouse model of ovarian cancer. Endocrinology. 151: 929-38. PMID 20056833 DOI: 10.1210/en.2009-0602  0.791
2009 Clark-Knowles KV, Senterman MK, Collins O, Vanderhyden BC. Conditional inactivation of Brca1, p53 and Rb in mouse ovaries results in the development of leiomyosarcomas. Plos One. 4: e8534. PMID 20046869 DOI: 10.1371/journal.pone.0008534  0.382
2009 Shah SP, Köbel M, Senz J, Morin RD, Clarke BA, Wiegand KC, Leung G, Zayed A, Mehl E, Kalloger SE, Sun M, Giuliany R, Yorida E, Jones S, Varhol R, ... ... Vanderhyden B, et al. Mutation of FOXL2 in granulosa-cell tumors of the ovary. The New England Journal of Medicine. 360: 2719-29. PMID 19516027 DOI: 10.1056/Nejmoa0902542  0.364
2008 Weberpals JI, Clark-Knowles KV, Vanderhyden BC. Sporadic epithelial ovarian cancer: clinical relevance of BRCA1 inhibition in the DNA damage and repair pathway. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 3259-67. PMID 18591560 DOI: 10.1200/JCO.2007.11.3902  0.328
2008 Salehi F, Dunfield L, Phillips KP, Krewski D, Vanderhyden BC. Risk factors for ovarian cancer: an overview with emphasis on hormonal factors. Journal of Toxicology and Environmental Health. Part B, Critical Reviews. 11: 301-21. PMID 18368558 DOI: 10.1080/10937400701876095  0.409
2008 Shaw TJ, Lacasse EC, Durkin JP, Vanderhyden BC. Downregulation of XIAP expression in ovarian cancer cells induces cell death in vitro and in vivo. International Journal of Cancer. 122: 1430-4. PMID 18027851 DOI: 10.1002/ijc.23278  0.468
2008 Laviolette LA, Garson K, Macdonald EA, Senterman MK, Courville K, Vanderhyden BC. Exogenous 17β-estradiol Results in an Earlier Onset of Ovarian Cancer and a Decreased Survival Time in a Transgenic Mouse Model of Ovarian Cancer. Biology of Reproduction. 78: 179-179. DOI: 10.1093/Biolreprod/78.S1.179  0.767
2007 Shaw TJ, Vanderhyden BC. AKT mediates the pro-survival effects of KIT in ovarian cancer cells and is a determinant of sensitivity to imatinib mesylate. Gynecologic Oncology. 105: 122-31. PMID 17169414 DOI: 10.1016/j.ygyno.2006.10.052  0.496
2007 Clark-Knowles KV, Garson K, Jonkers J, Vanderhyden BC. Conditional inactivation of Brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes. Experimental Cell Research. 313: 133-45. PMID 17070800 DOI: 10.1016/j.yexcr.2006.09.026  0.343
2006 Yao DS, Li L, Garson K, Vanderhyden BC. [*OPCML gene transferred by recombinant lentiviruses in vitro and its inhibition to ovarian cancer cells]. Zhonghua Fu Chan Ke Za Zhi. 41: 333-8. PMID 16762191  0.374
2006 Chambers AF, Vanderhyden BC. Ovarian cancer biomarkers in urine. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 323-7. PMID 16428467 DOI: 10.1158/1078-0432.CCR-05-2563  0.387
2005 Garson K, Shaw TJ, Clark KV, Yao DS, Vanderhyden BC. Models of ovarian cancer--are we there yet? Molecular and Cellular Endocrinology. 239: 15-26. PMID 15955618 DOI: 10.1016/j.mce.2005.03.019  0.491
2005 Vanderhyden BC. Loss of ovarian function and the risk of ovarian cancer. Cell and Tissue Research. 322: 117-24. PMID 15902502 DOI: 10.1007/s00441-005-1100-1  0.451
2005 Steller MD, Shaw TJ, Vanderhyden BC, Ethier JF. Inhibin resistance is associated with aggressive tumorigenicity of ovarian cancer cells. Molecular Cancer Research : McR. 3: 50-61. PMID 15671249  0.498
2004 Shaw TJ, Senterman MK, Dawson K, Crane CA, Vanderhyden BC. Characterization of intraperitoneal, orthotopic, and metastatic xenograft models of human ovarian cancer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 1032-42. PMID 15564135 DOI: 10.1016/j.ymthe.2004.08.013  0.474
2003 Hamilton TC, Connolly DC, Nikitin AY, Garson K, Vanderhyden BC. Translational research in ovarian cancer: A must International Journal of Gynecological Cancer. 13: 220-230. PMID 14656284 DOI: 10.1111/J.1525-1438.2003.13350.X  0.44
2003 Vanderhyden BC, Shaw TJ, Ethier JF. Animal models of ovarian cancer. Reproductive Biology and Endocrinology : Rb&E. 1: 67. PMID 14613552 DOI: 10.1186/1477-7827-1-67  0.469
2003 Garson K, Macdonald E, Dubé M, Bao R, Hamilton TC, Vanderhyden BC. Generation of tumors in transgenic mice expressing the SV40 T antigen under the control of ovarian-specific promoter 1. Journal of the Society For Gynecologic Investigation. 10: 244-50. PMID 12759154 DOI: 10.1016/S1071-5576(03)00073-X  0.368
2003 Connolly DC, Bao R, Nikitin AY, Stephens KC, Poole TW, Hua X, Harris SS, Vanderhyden BC, Hamilton TC. Female mice chimeric for expression of the simian virus 40 TAg under control of the MISIIR promoter develop epithelial ovarian cancer. Cancer Research. 63: 1389-97. PMID 12649204  0.452
2003 Hamilton TC, Connolly DC, Nikitin AY, Garson K, Vanderhyden BC. Translational research in ovarian cancer: a must International Journal of Gynecologic Cancer. 13: 220-230. DOI: 10.1136/ijgc-00009577-200311001-00016  0.44
2002 Vanderhyden B. Molecular basis of ovarian development and function. Frontiers in Bioscience : a Journal and Virtual Library. 7: d2006-22. PMID 12161348 DOI: 10.2741/Vander  0.443
2002 Shaw TJ, Keszthelyi EJ, Tonary AM, Cada M, Vanderhyden BC. Cyclic AMP in ovarian cancer cells both inhibits proliferation and increases c-KIT expression. Experimental Cell Research. 273: 95-106. PMID 11795950 DOI: 10.1006/Excr.2001.5426  0.76
2001 Li J, Feng Q, Kim JM, Schneiderman D, Liston P, Li M, Vanderhyden B, Faught W, Fung MFK, Senterman M, Korneluk RG, Tsang BK. Human ovarian cancer and cisplatin resistance: Possible role of inhibitor of apoptosis proteins Endocrinology. 142: 370-380. PMID 11145600 DOI: 10.1210/Endo.142.1.7897  0.432
2000 Tonary AM, Macdonald EA, Faught W, Senterman MK, Vanderhyden BC. Lack of expression of c-KIT in ovarian cancers is associated with poor prognosis. International Journal of Cancer. Journal International Du Cancer. 89: 242-50. PMID 10861500 DOI: 10.1002/1097-0215(20000520)89:3<242::Aid-Ijc6>3.0.Co;2-6  0.753
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