| Year |
Citation |
Score |
| 2020 |
Sulaiman A, McGarry S, Chambers J, Al-Kadi E, Phan A, Li L, Mediratta K, Dimitroulakos J, Addison C, Li X, Wang L. Targeting Hypoxia Sensitizes TNBC to Cisplatin and Promotes Inhibition of Both Bulk and Cancer Stem Cells. International Journal of Molecular Sciences. 21. PMID 32806648 DOI: 10.3390/Ijms21165788 |
0.453 |
|
| 2018 |
Tam RY, Yockell-Lelièvre J, Smith LJ, Julian LM, Baker AEG, Choey C, Hasim MS, Dimitroulakos J, Stanford WL, Shoichet MS. Rationally Designed 3D Hydrogels Model Invasive Lung Diseases Enabling High-Content Drug Screening. Advanced Materials (Deerfield Beach, Fla.). e1806214. PMID 30589121 DOI: 10.1002/Adma.201806214 |
0.353 |
|
| 2018 |
Quimby AE, Lebo NL, Griffiths R, Hall S, Dimitroulakos J, Johnson-Obaseki S. Does metformin usage improve survival in head and neck squamous cell carcinoma? A population-based study. Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'Oto-Rhino-Laryngologie Et De Chirurgie Cervico-Faciale. 47: 74. PMID 30514404 DOI: 10.1186/S40463-018-0322-7 |
0.324 |
|
| 2018 |
Sulaiman A, McGarry S, Lam KM, El-Sahli S, Chambers J, Kaczmarek S, Li L, Addison C, Dimitroulakos J, Arnaout A, Nessim C, Yao Z, Ji G, Song H, Liu S, et al. Co-inhibition of mTORC1, HDAC and ESR1α retards the growth of triple-negative breast cancer and suppresses cancer stem cells. Cell Death & Disease. 9: 815. PMID 30050079 DOI: 10.1038/S41419-018-0811-7 |
0.432 |
|
| 2018 |
Hasim MS, Nessim C, Villeneuve PJ, Vanderhyden BC, Dimitroulakos J. Activating Transcription Factor 3 as a Novel Regulator of Chemotherapy Response in Breast Cancer. Translational Oncology. 11: 988-998. PMID 29940414 DOI: 10.1016/J.Tranon.2018.06.001 |
0.469 |
|
| 2018 |
Lebo NL, Griffiths R, Hall S, Dimitroulakos J, Johnson-Obaseki S. Effect of statin use on oncologic outcomes in head and neck squamous cell carcinoma. Head & Neck. PMID 29934959 DOI: 10.1002/Hed.25152 |
0.331 |
|
| 2018 |
Sulaiman A, McGarry S, Li L, Jia D, Ooi S, Addison C, Dimitroulakos J, Arnaout A, Nessim C, Yao Z, Ji G, Song H, Gadde S, Li X, Wang L. Dual inhibition of Wnt and Yes-associated protein signaling retards the growth of triple negative breast cancer in both mesenchymal and epithelial states. Molecular Oncology. PMID 29316250 DOI: 10.1002/1878-0261.12167 |
0.375 |
|
| 2017 |
Atherton MJ, Stephenson KB, Pol J, Wang F, Lefebvre C, Stojdl DF, Nikota JK, Dvorkin-Gheva A, Nguyen A, Chen L, Johnson-Obaseki S, Villeneuve PJ, Diallo JS, Dimitroulakos J, Wan Y, et al. Customized Viral Immunotherapy for HPV-Associated Cancer. Cancer Immunology Research. PMID 28912369 DOI: 10.1158/2326-6066.Cir-17-0102 |
0.326 |
|
| 2017 |
Weberpals JI, Lo B, Duciaume MM, Spaans JN, Clancy AA, Dimitroulakos J, Goss GD, Sekhon HS. Vulvar squamous cell carcinoma (VSCC) as two diseases: HPV status identifies distinct mutational profiles including oncogenic fibroblast growth factor receptor 3. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28377483 DOI: 10.1158/1078-0432.Ccr-16-3230 |
0.379 |
|
| 2016 |
Sulaiman A, Sulaiman B, Khouri L, McGarry S, Nessim C, Arnaout A, Li X, Addison C, Dimitroulakos J, Wang L. Both bulk and cancer stem cell subpopulations in triple-negative breast cancer are susceptible to Wnt, HDAC and ERα co-inhibition. Febs Letters. PMID 27859250 DOI: 10.1002/1873-3468.12496 |
0.413 |
|
| 2016 |
Bar J, Hasim MS, Baghai T, Niknejad N, Perkins TJ, Stewart DJ, Sekhon HS, Villeneuve PJ, Dimitroulakos J. Induction of Activating Transcription Factor 3 Is Associated with Cisplatin Responsiveness in Non-Small Cell Lung Carcinoma Cells. Neoplasia (New York, N.Y.). 18: 525-35. PMID 27659012 DOI: 10.1016/J.Neo.2016.07.004 |
0.48 |
|
| 2016 |
Howe GA, Xiao B, Zhao H, Al-Zahrani KN, Hasim MS, Villeneuve J, Sekhon HS, Goss GD, Sabourin LA, Dimitroulakos J, Addison CL. Focal Adhesion Kinase Inhibitors in Combination with Erlotinib Demonstrate Enhanced Anti-Tumor Activity in Non-Small Cell Lung Cancer. Plos One. 11: e0150567. PMID 26962872 DOI: 10.1371/Journal.Pone.0150567 |
0.441 |
|
| 2015 |
Bar J, Ding K, Zhao H, Han L, Laurie SA, Seymour L, Addison CL, Shepherd FA, Goss GD, Dimitroulakos J, Bradbury PA. Angiotensin-Converting Enzyme and Aldosterone Serum Levels as Prognostic and Predictive Biomarkers for Cediranib in NCIC Clinical Trials Group Study BR.24. Clinical Lung Cancer. PMID 26081815 DOI: 10.1016/J.Cllc.2015.05.002 |
0.328 |
|
| 2015 |
Bar J, Gorn-Hondermann I, Moretto P, Perkins TJ, Niknejad N, Stewart DJ, Goss GD, Dimitroulakos J. miR Profiling Identifies Cyclin-Dependent Kinase 6 Downregulation as a Potential Mechanism of Acquired Cisplatin Resistance in Non-Small-Cell Lung Carcinoma. Clinical Lung Cancer. PMID 25703099 DOI: 10.1016/J.Cllc.2015.01.008 |
0.379 |
|
| 2014 |
Bar J, Gorn-Hondermann I, Moretto P, Niknejad N, Stewart DJ, Goss GD, Dimitroulakos J. 154PMIR PROFILING IDENTIFIES CDK6 DOWN-REGULATION AS A POTENTIAL MECHANISM OF ACQUIRED CISPLATIN RESISTANCE IN NON-SMALL CELL LUNG CARCINOMA. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 25: iv53-iv54. PMID 28170821 DOI: 10.1093/Annonc/Mdu325.4 |
0.396 |
|
| 2014 |
Dayekh K, Johnson-Obaseki S, Corsten M, Villeneuve PJ, Sekhon HS, Weberpals JI, Dimitroulakos J. Monensin inhibits epidermal growth factor receptor trafficking and activation: synergistic cytotoxicity in combination with EGFR inhibitors. Molecular Cancer Therapeutics. 13: 2559-71. PMID 25189541 DOI: 10.1158/1535-7163.Mct-13-1086 |
0.503 |
|
| 2014 |
Niknejad N, Gorn-Hondermann I, Ma L, Zahr S, Johnson-Obeseki S, Corsten M, Dimitroulakos J. Lovastatin-induced apoptosis is mediated by activating transcription factor 3 and enhanced in combination with salubrinal. International Journal of Cancer. 134: 268-79. PMID 23824972 DOI: 10.1002/Ijc.28369 |
0.466 |
|
| 2014 |
Bar J, Stewart D, Glenwood GD, Villeneuve PJ, Dimitroulakos J. Abstract A16: Induction of activating transcription factor 3 is associated with cisplatin responsiveness in NSCLC: A potential predictive biomarker of response. Clinical Cancer Research. 20. DOI: 10.1158/1078-0432.14Aacriaslc-A16 |
0.436 |
|
| 2013 |
Honeywell DR, Cabrita MA, Zhao H, Dimitroulakos J, Addison CL. miR-105 Inhibits Prostate Tumour Growth by Suppressing CDK6 Levels Plos One. 8. PMID 23950948 DOI: 10.1371/Journal.Pone.0070515 |
0.349 |
|
| 2013 |
Bar J, Ding K, Zhao H, Laurie SA, Han L, Shepherd FA, Addison CL, Goss GD, Dimitroulakos J, Bradbury PA. Exploratory analysis of angiotensin converting enzyme (ACE) and aldosterone (Ald) serum levels as prognostic and predictive biomarkers on the NCIC CTG BR24 trial. Journal of Clinical Oncology. 31: 8048-8048. DOI: 10.1200/Jco.2013.31.15_Suppl.8048 |
0.313 |
|
| 2013 |
Bar J, Gorn-Hondermann I, Stephanie R, Moretto P, Shiran I, Jessel S, Perelman M, Heller E, Kamer I, Daniel-Meshulam I, Goss GD, Dimitroulakos J. Abstract 895: Activating transcription factor 3 (ATF3) down-regulation correlates with platinum resistance in non-small cell lung cancer (NSCLC). Cancer Research. 73: 895-895. DOI: 10.1158/1538-7445.Am2013-895 |
0.429 |
|
| 2012 |
Ma L, Niknejad N, Gorn-Hondermann I, Dayekh K, Dimitroulakos J. Lovastatin induces multiple stress pathways including LKB1/AMPK activation that regulate its cytotoxic effects in squamous cell carcinoma cells. Plos One. 7: e46055. PMID 23029387 DOI: 10.1371/Journal.Pone.0046055 |
0.37 |
|
| 2012 |
Le Boeuf F, Niknejad N, Wang J, Auer R, Weberpals JI, Bell JC, Dimitroulakos J. Sensitivity of cervical carcinoma cells to vesicular stomatitis virus-induced oncolysis: Potential role of human papilloma virus infection International Journal of Cancer. 131: E204-E215. PMID 22173567 DOI: 10.1002/Ijc.27404 |
0.388 |
|
| 2012 |
Vickers MM, Bar J, Gorn-Hondermann I, Yarom N, Daneshmand M, Hanson JE, Addison CL, Asmis TR, Jonker DJ, Maroun J, Lorimer IA, Goss GD, Dimitroulakos J. Stage-dependent differential expression of microRNAs in colorectal cancer: potential role as markers of metastatic disease. Clinical & Experimental Metastasis. 29: 123-32. PMID 22120473 DOI: 10.1007/S10585-011-9435-3 |
0.304 |
|
| 2011 |
Bar J, Gorn-Hundermann I, Reid S, O'Brien A, Niknejad N, Goss GD, Dimitroulakos J. Activating transcription factor 3 (ATF3) as a potential biomarker of platinum sensitivity in non-small cell lung cancer (NSCLC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: e21012. PMID 28022359 DOI: 10.1200/Jco.2011.29.15_Suppl.E21012 |
0.413 |
|
| 2011 |
Weberpals JI, O'Brien AM, Niknejad N, Garbuio KD, Clark-Knowles KV, Dimitroulakos J. The effect of the histone deacetylase inhibitor M344 on BRCA1 expression in breast and ovarian cancer cells. Cancer Cell International. 11: 29. PMID 21854619 DOI: 10.1186/1475-2867-11-29 |
0.406 |
|
| 2011 |
Bar J, Perez-Iratxeta C, Gorn-hundermann I, Stefanie R, Goss GD, Dimitroulakos J. Abstract 4949: microRNA (miR) analysis as a tool for discovering platinum resistance mechanisms in non-small cell lung cancer (NSCLC) Cancer Research. 71: 4949-4949. DOI: 10.1158/1538-7445.Am2011-4949 |
0.349 |
|
| 2010 |
Zhao TT, Trinh D, Addison CL, Dimitroulakos J. Lovastatin inhibits VEGFR and AKT activation: Synergistic cytotoxicity in combination with VEGFR inhibitors Plos One. 5: 1-11. PMID 20838437 DOI: 10.1371/Journal.Pone.0012563 |
0.425 |
|
| 2010 |
St Germain C, O'Brien A, Dimitroulakos J. Activating Transcription Factor 3 regulates in part the enhanced tumour cell cytotoxicity of the histone deacetylase inhibitor M344 and cisplatin in combination. Cancer Cell International. 10: 32. PMID 20828393 DOI: 10.1186/1475-2867-10-32 |
0.417 |
|
| 2010 |
Arnold DE, Gagne C, Niknejad N, McBurney MW, Dimitroulakos J. Lovastatin induces neuronal differentiation and apoptosis of embryonal carcinoma and neuroblastoma cells: enhanced differentiation and apoptosis in combination with dbcAMP. Molecular and Cellular Biochemistry. 345: 1-11. PMID 20694854 DOI: 10.1007/S11010-010-0553-Z |
0.434 |
|
| 2010 |
St Germain C, Niknejad N, Ma L, Garbuio K, Hai T, Dimitroulakos J. Cisplatin induces cytotoxicity through the mitogen-activated protein kinase pathways and activating transcription factor 3. Neoplasia (New York, N.Y.). 12: 527-38. PMID 20651982 DOI: 10.1593/Neo.92048 |
0.453 |
|
| 2010 |
Zhao TT, Le Francois BG, Goss G, Ding K, Bradbury PA, Dimitroulakos J. Lovastatin inhibits EGFR dimerization and AKT activation in squamous cell carcinoma cells: Potential regulation by targeting rho proteins Oncogene. 29: 4682-4692. PMID 20562912 DOI: 10.1038/Onc.2010.219 |
0.466 |
|
| 2010 |
Zhao TT, Dimitroulakos J. Abstract A53: Lovastatin inhibits EGFR dimerization and AKT activation in squamous cell carcinoma cells: Potential regulation through targeting rho proteins Clinical Cancer Research. 16. DOI: 10.1158/1078-0432.Tcmusa10-A53 |
0.48 |
|
| 2009 |
Weberpals J, Garbuio K, O'Brien A, Clark-Knowles K, Doucette S, Antoniouk O, Goss G, Dimitroulakos J. The DNA repair proteins BRCA1 and ERCC1 as predictive markers in sporadic ovarian cancer. International Journal of Cancer. 124: 806-15. PMID 19035454 DOI: 10.1002/ijc.23987 |
0.311 |
|
| 2009 |
Weberpals JI, O'Brien A, Garbuio K, Clark-Knowles K, Dimitroulakos J. Investigation of HDAC inhibition targeting of BRCA1 expression as a mechanism to enhance platinum sensitivity in breast and ovarian cancer Journal of Clinical Oncology. 27. DOI: 10.1200/Jco.2009.27.15_Suppl.E22017 |
0.387 |
|
| 2009 |
Weberpals JI, O'Brien A, Garbuio K, Clark‐Knowles K, Dimitroulakos J. Abstract B174: The effect of histone deacetylase inhibition on BRCA1 expression: A potential novel mechanism for enhancing platinum sensitivity in breast and ovarian cancer Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B174 |
0.428 |
|
| 2008 |
Cemeus C, Zhao TT, Barrett GM, Lorimer IA, Dimitroulakos J. Lovastatin enhances gefitinib activity in glioblastoma cells irrespective of EGFRvIII and PTEN status. Journal of Neuro-Oncology. 90: 9-17. PMID 18566746 DOI: 10.1007/S11060-008-9627-0 |
0.462 |
|
| 2008 |
Weberpals JI, Clark-Knowles K, O'Brien A, Antoniouk O, Garbuio K, Dimitroulakos J. The evaluation of BRCA1 and ERCC1 expression as predictors of platinum response in ovarian cancer Journal of Clinical Oncology. 26: 5587-5587. DOI: 10.1200/Jco.2008.26.15_Suppl.5587 |
0.349 |
|
| 2007 |
Niknejad N, Morley M, Dimitroulakos J. Activation of the integrated stress response regulates lovastatin-induced apoptosis. The Journal of Biological Chemistry. 282: 29748-56. PMID 17699156 DOI: 10.1074/Jbc.M705859200 |
0.427 |
|
| 2006 |
Dimitroulakos J, Lorimer IA, Goss G. Strategies to enhance epidermal growth factor inhibition: targeting the mevalonate pathway. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4426s-4431s. PMID 16857822 DOI: 10.1158/1078-0432.Ccr-06-0089 |
0.457 |
|
| 2003 |
Mantha AJ, McFee KE, Niknejad N, Goss G, Lorimer IA, Dimitroulakos J. Epidermal growth factor receptor-targeted therapy potentiates lovastatin-induced apoptosis in head and neck squamous cell carcinoma cells. Journal of Cancer Research and Clinical Oncology. 129: 631-41. PMID 12942316 DOI: 10.1007/S00432-003-0490-2 |
0.45 |
|
| 2002 |
Dimitroulakos J, Marhin WH, Tokunaga J, Irish J, Gullane P, Penn LZ, Kamel-Reid S. Microarray and biochemical analysis of lovastatin-induced apoptosis of squamous cell carcinomas. Neoplasia (New York, N.Y.). 4: 337-46. PMID 12082550 DOI: 10.1038/Sj.Neo.7900247 |
0.376 |
|
| 2001 |
Dimitroulakos J, Ye LY, Benzaquen M, Moore MJ, Kamel-Reid S, Freedman MH, Yeger H, Penn LZ. Differential sensitivity of various pediatric cancers and squamous cell carcinomas to lovastatin-induced apoptosis: Therapeutic implications Clinical Cancer Research. 7: 158-167. PMID 11205904 |
0.375 |
|
| 1999 |
Macaulay RJ, Wang W, Dimitroulakos J, Becker LE, Yeger H. Lovastatin-induced apoptosis of human medulloblastoma cell lines in vitro. Journal of Neuro-Oncology. 42: 1-11. PMID 10360474 DOI: 10.1023/A:1006164406202 |
0.329 |
|
| 1999 |
Dimitroulakos J, Nohynek D, Backway KL, Medley DW, Yeger H, Freedman MH, Minden MD, Penn LZ. Increased sensitivity of acute myeloid leukemias to lovastatin-induced apoptosis: A potential therapeutic approach Blood. 93: 1308-1318. PMID 9949174 DOI: 10.1182/Blood.V93.4.1308.404K08_1308_1318 |
0.33 |
|
| 1996 |
Dimitroulakos J, Yeger H. HMG-CoA reductase mediates the biological effects of retinoic acid on human neuroblastoma cells: Lovastatin specifically targets P-glycoprotein-expressing cells Nature Medicine. 2: 326-333. PMID 8612233 DOI: 10.1038/Nm0396-326 |
0.318 |
|
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