| Year |
Citation |
Score |
| 2020 |
McGrath M, Hoyt H, Pence A, Jayakar SS, Zhou X, Forman SA, Cohen JB, Miller KW, Raines DE. Competitive Antagonism of Etomidate Action by Diazepam: In Vitro GABAA Receptor and In Vivo Zebrafish Studies. Anesthesiology. PMID 32541553 DOI: 10.1097/Aln.0000000000003403 |
0.349 |
|
| 2020 |
Jayakar SS, Chiara DC, Zhou X, Wu B, Bruzik KS, Miller KW, Cohen JB. Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABA) receptors. The Journal of Biological Chemistry. PMID 32540960 DOI: 10.1074/Jbc.Ra120.013452 |
0.341 |
|
| 2020 |
Shalabi AR, Yu Z, Zhou X, Jounaidi Y, Chen H, Dai J, Kent DE, Feng HJ, Forman SA, Cohen JB, Bruzik KS, Miller KW. A potent photoreactive general anesthetic with novel binding site selectivity for GABA receptors. European Journal of Medicinal Chemistry. 194: 112261. PMID 32247113 DOI: 10.1016/J.Ejmech.2020.112261 |
0.315 |
|
| 2019 |
Kent DE, Savechenkov PY, Bruzik KS, Miller KW. Binding Site Location on GABA Rs Determines Whether Mixtures of Intravenous General Anesthetics Interact Synergistically or Additively in vivo. British Journal of Pharmacology. PMID 31454409 DOI: 10.1111/Bph.14843 |
0.318 |
|
| 2019 |
Masiulis S, Desai R, Uchański T, Serna Martin I, Laverty D, Karia D, Malinauskas T, Zivanov J, Pardon E, Kotecha A, Steyaert J, Miller KW, Aricescu AR. GABA receptor signalling mechanisms revealed by structural pharmacology. Nature. PMID 30602790 DOI: 10.1038/s41586-018-0832-5 |
0.322 |
|
| 2019 |
Laverty D, Desai R, Uchański T, Masiulis S, Stec WJ, Malinauskas T, Zivanov J, Pardon E, Steyaert J, Miller KW, Aricescu AR. Cryo-EM structure of the human α1β3γ2 GABA receptor in a lipid bilayer. Nature. PMID 30602789 DOI: 10.1038/S41586-018-0833-4 |
0.333 |
|
| 2018 |
Wu B, Jayakar SS, Zhou X, Titterton K, Chiara DC, Szabo AL, Savechenkov PY, Kent DE, Cohen JB, Forman SA, Miller KW, Bruzik KS. Inhibitable photolabeling by neurosteroid diazirine analog in the β3-Subunit of human hetereopentameric type A GABA receptors. European Journal of Medicinal Chemistry. 162: 810-824. PMID 30544077 DOI: 10.1016/J.Ejmech.2018.11.019 |
0.345 |
|
| 2018 |
McGrath M, Yu Z, Jayakar SS, Ma C, Tolia M, Zhou X, Miller KW, Cohen JB, Raines DE. Etomidate and Etomidate Analog Binding and Positive Modulation of γ-Aminobutyric Acid Type A Receptors: Evidence for a State-dependent Cutoff Effect. Anesthesiology. PMID 30052529 DOI: 10.1097/Aln.0000000000002356 |
0.332 |
|
| 2018 |
Woll KA, Zhou X, Bhanu NV, Garcia BA, Covarrubias M, Miller KW, Eckenhoff RG. Identification of binding sites contributing to volatile anesthetic effects on GABA type A receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201701347R. PMID 29505303 DOI: 10.1096/Fj.201701347R |
0.345 |
|
| 2018 |
Zhou X, Desai R, Zhang Y, Stec WJ, Miller KW, Jounaidi Y. High-level production and purification in a functional state of an extrasynaptic gamma-aminobutyric acid type A receptor containing α4β3δ subunits. Plos One. 13: e0191583. PMID 29352320 DOI: 10.1371/Journal.Pone.0191583 |
0.34 |
|
| 2017 |
Ma C, Pejo E, McGrath M, Jayakar SS, Zhou X, Miller KW, Cohen JB, Raines DE. Competitive Antagonism of Anesthetic Action at the γ-Aminobutyric Acid Type A Receptor by a Novel Etomidate Analog with Low Intrinsic Efficacy. Anesthesiology. PMID 28857763 DOI: 10.1097/Aln.0000000000001840 |
0.303 |
|
| 2017 |
Savechenkov PY, Chiara DC, Desai R, Stern AT, Zhou X, Ziemba AM, Szabo AL, Zhang Y, Cohen JB, Forman SA, Miller KW, Bruzik KS. Synthesis and pharmacological evaluation of neurosteroid photoaffinity ligands. European Journal of Medicinal Chemistry. 136: 334-347. PMID 28505538 DOI: 10.1016/J.Ejmech.2017.04.043 |
0.344 |
|
| 2016 |
Chiara DC, Jounaidi Y, Zhou X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB. General Anesthetic Binding Sites in Human α4β3δ γ-Aminobutyric Acid Type-A Receptors (GABAAR). The Journal of Biological Chemistry. PMID 27821594 DOI: 10.1074/Jbc.M116.753335 |
0.325 |
|
| 2016 |
Amlong CA, Perkins MG, Houle TT, Miller KW, Pearce RA. Contrasting Effects of the γ-Aminobutyric Acid Type A Receptor β3 Subunit N265M Mutation on Loss of Righting Reflexes Induced by Etomidate and the Novel Anesthetic Barbiturate R-mTFD-MPAB. Anesthesia and Analgesia. PMID 27331778 DOI: 10.1213/Ane.0000000000001358 |
0.305 |
|
| 2016 |
Forman SA, Miller KW. Mapping General Anesthetic Sites in Heteromeric γ-Aminobutyric Acid Type A Receptors Reveals a Potential For Targeting Receptor Subtypes. Anesthesia and Analgesia. PMID 27167687 DOI: 10.1213/Ane.0000000000001368 |
0.35 |
|
| 2016 |
Zhang Y, Sarver JL, Zhou X, Cafiso DS, Miller KW. Pulsed Electron Paramagnetic Resonance of Spin Labeled Human GABA(A)Rs Functionally Reconstituted in Lipid Bilayers Suggests there is Space for Lipids between the Subunits Biophysical Journal. 110: 455a. DOI: 10.1016/J.Bpj.2015.11.2439 |
0.317 |
|
| 2016 |
Chiara DC, Savechenkov PY, Zhou X, Desai R, Stern AT, Zhang Y, Forman SA, Bruzik KS, Miller KW, Cohen JB. Interactions of a Photoreactive Steroid Anesthetic (F4N3-Alphaxalone) with Human α1β3γ2 GABA-A Receptors Biophysical Journal. 110: 455a. DOI: 10.1016/J.Bpj.2015.11.2438 |
0.352 |
|
| 2016 |
Jayakar SS, Zhou X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB. Identifying GABA-A Receptor Modulators that Bind to Intersubunit Sites in the GABA-A Receptor Transmembrane Domain Biophysical Journal. 110: 454a-455a. DOI: 10.1016/J.Bpj.2015.11.2437 |
0.33 |
|
| 2015 |
Desai R, Savechenkov PY, Zolkowska D, Ge RL, Rogawski MA, Bruzik KS, Forman SA, Raines DE, Miller KW. Contrasting actions of a convulsant barbiturate and its anti-convulsant enantiomer on the α1β3γ2L GABAA receptor account for their in vivo effects. The Journal of Physiology. PMID 26378885 DOI: 10.1113/Jp270971 |
0.346 |
|
| 2015 |
Dodson A, Zabaglo L, Yeo B, Miller K, Smith I, Dowsett M. Risk of recurrence estimates with IHC4+C are tolerant of variations in staining and scoring: an analytical validity study. Journal of Clinical Pathology. PMID 26281860 DOI: 10.1136/jclinpath-2015-203212 |
0.36 |
|
| 2015 |
Jayakar SS, Zhou X, Savechenkov PY, Chiara DC, Desai R, Bruzik KS, Miller KW, Cohen JB. Positive and Negative Allosteric Modulation of an α1β3γ2 γ-Aminobutyric acid Type A (GABAA) Receptor by Binding to a Site in the Transmembrane Domain at the γ+-β- Interface. The Journal of Biological Chemistry. PMID 26229099 DOI: 10.1074/Jbc.M115.672006 |
0.335 |
|
| 2015 |
Forman SA, Chiara DC, Miller KW. Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors. Neuropharmacology. 96: 169-77. PMID 25316107 DOI: 10.1016/J.Neuropharm.2014.10.002 |
0.369 |
|
| 2014 |
Jayakar SS, Zhou X, Chiara DC, Dostalova Z, Savechenkov PY, Bruzik KS, Dailey WP, Miller KW, Eckenhoff RG, Cohen JB. Multiple propofol-binding sites in a γ-aminobutyric acid type A receptor (GABAAR) identified using a photoreactive propofol analog. The Journal of Biological Chemistry. 289: 27456-68. PMID 25086038 DOI: 10.1074/Jbc.M114.581728 |
0.31 |
|
| 2014 |
Dostalova Z, Zhou X, Liu A, Zhang X, Zhang Y, Desai R, Forman SA, Miller KW. Human α1β3γ2L gamma-aminobutyric acid type A receptors: High-level production and purification in a functional state. Protein Science : a Publication of the Protein Society. 23: 157-66. PMID 24288268 DOI: 10.1002/Pro.2401 |
0.337 |
|
| 2014 |
Olsen RW, Li GD, Wallner M, Trudell JR, Bertaccini EJ, Lindahl E, Miller KW, Alkana RL, Davies DL. Structural models of ligand-gated ion channels: sites of action for anesthetics and ethanol. Alcoholism, Clinical and Experimental Research. 38: 595-603. PMID 24164436 DOI: 10.1111/Acer.12283 |
0.353 |
|
| 2014 |
Zhang Y, Jounaidi Y, Sarver JL, Zhou X, Cafiso DS, Miller KW. γ-Aminobutyric Acid Induced Conformational Change in GABAAR Measured by Pulsed Electron Paramagnetic Resonance Biophysical Journal. 106: 547a. DOI: 10.1016/J.Bpj.2013.11.3044 |
0.332 |
|
| 2013 |
Chiara DC, Jayakar SS, Zhou X, Zhang X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB. Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human α1β3γ2 γ-aminobutyric acid type A (GABAA) receptor. The Journal of Biological Chemistry. 288: 19343-57. PMID 23677991 DOI: 10.1074/Jbc.M113.479725 |
0.345 |
|
| 2013 |
Desai R, Miller KW, Raines DE. The pyrrole etomidate analog carboetomidate potently inhibits human 5-HT3A receptor function: comparisons with etomidate and potential implications for emetogenesis. Anesthesia and Analgesia. 116: 573-9. PMID 23400978 DOI: 10.1213/Ane.0B013E31827D204D |
0.307 |
|
| 2013 |
Jayakar SS, Zhou X, Dostalova Z, Dailey WP, Miller KW, Eckenhoff RG, Cohen JB. Identifying the Propofol Binding Site(S) in Heterologously Expressed Human Alpha1 Beta3 Gaba-A Receptors using a Photoreactive Propofol Analog Biophysical Journal. 104: 637a. DOI: 10.1016/J.Bpj.2012.11.3519 |
0.319 |
|
| 2012 |
Savechenkov PY, Zhang X, Chiara DC, Stewart DS, Ge R, Zhou X, Raines DE, Cohen JB, Forman SA, Miller KW, Bruzik KS. Allyl m-trifluoromethyldiazirine mephobarbital: an unusually potent enantioselective and photoreactive barbiturate general anesthetic. Journal of Medicinal Chemistry. 55: 6554-65. PMID 22734650 DOI: 10.1021/Jm300631E |
0.327 |
|
| 2012 |
Shanmugasundararaj S, Lehle S, Yamodo HI, Husain SS, Tseng C, Nguyen K, Addona GH, Miller KW. The location and nature of general anesthetic binding sites on the active conformation of firefly luciferase; a time resolved photolabeling study. Plos One. 7: e29854. PMID 22272253 DOI: 10.1371/Journal.Pone.0029854 |
0.312 |
|
| 2012 |
Chiara DC, Dostalova Z, Jayakar SS, Zhou X, Miller KW, Cohen JB. Mapping general anesthetic binding site(s) in human α1β3 γ-aminobutyric acid type A receptors with [³H]TDBzl-etomidate, a photoreactive etomidate analogue. Biochemistry. 51: 836-47. PMID 22243422 DOI: 10.1021/Bi201772M |
0.31 |
|
| 2011 |
Stewart DS, Savechenkov PY, Dostalova Z, Chiara DC, Ge R, Raines DE, Cohen JB, Forman SA, Bruzik KS, Miller KW. p-(4-Azipentyl)propofol: a potent photoreactive general anesthetic derivative of propofol. Journal of Medicinal Chemistry. 54: 8124-35. PMID 22029276 DOI: 10.1021/Jm200943F |
0.34 |
|
| 2011 |
Forman SA, Miller KW. Anesthetic sites and allosteric mechanisms of action on Cys-loop ligand-gated ion channels. Canadian Journal of Anaesthesia = Journal Canadien D'AnesthéSie. 58: 191-205. PMID 21213095 DOI: 10.1007/S12630-010-9419-9 |
0.348 |
|
| 2011 |
Jayakar∗ SS, Dostalova Z, Chiara DC, Zhou X, Liu A, Miller KW, Cohen JB. Identifying an Etomidate Binding Site in Heterologously Expressed Human Alpha1/Beta3 GABAA Receptors (GABAAR) Using Photoactive Etomidate Analogs Biophysical Journal. 100: 271a. DOI: 10.1016/J.Bpj.2010.12.1689 |
0.316 |
|
| 2010 |
Husain SS, Stewart D, Desai R, Hamouda AK, Li SG, Kelly E, Dostalova Z, Zhou X, Cotten JF, Raines DE, Olsen RW, Cohen JB, Forman SA, Miller KW. p-Trifluoromethyldiazirinyl-etomidate: a potent photoreactive general anesthetic derivative of etomidate that is selective for ligand-gated cationic ion channels. Journal of Medicinal Chemistry. 53: 6432-44. PMID 20704351 DOI: 10.1021/Jm100498U |
0.323 |
|
| 2010 |
Dostalova Z, Liu A, Zhou X, Farmer SL, Krenzel ES, Arevalo E, Desai R, Feinberg-Zadek PL, Davies PA, Yamodo IH, Forman SA, Miller KW. High-level expression and purification of Cys-loop ligand-gated ion channels in a tetracycline-inducible stable mammalian cell line: GABAA and serotonin receptors. Protein Science : a Publication of the Protein Society. 19: 1728-38. PMID 20662008 DOI: 10.1002/Pro.456 |
0.333 |
|
| 2010 |
Chiara DC, Dostalova Z, Liu A, Zhou X, Forman SA, Miller KW, Cohen JB. Characterization of the Etomidate Binding Site in Expressed α1β3 GABAAR by Photoaffinity Labeling Biophysical Journal. 98: 704a. DOI: 10.1016/J.Bpj.2009.12.3862 |
0.342 |
|
| 2009 |
Gilligan PJ, He L, Clarke T, Tivitmahaisoon P, Lelas S, Li YW, Heman K, Fitzgerald L, Miller K, Zhang G, Marshall A, Krause C, McElroy J, Ward K, Shen H, et al. 8-(4-Methoxyphenyl)pyrazolo[1,5-a]-1,3,5-triazines: selective and centrally active corticotropin-releasing factor receptor-1 (CRF1) antagonists. Journal of Medicinal Chemistry. 52: 3073-83. PMID 19361210 DOI: 10.1021/Jm9000242 |
0.301 |
|
| 2009 |
Chiara DC, Hong FH, Arevalo E, Husain SS, Miller KW, Forman SA, Cohen JB. Time-resolved photolabeling of the nicotinic acetylcholine receptor by [3H]azietomidate, an open-state inhibitor. Molecular Pharmacology. 75: 1084-95. PMID 19218367 DOI: 10.1124/Mol.108.054353 |
0.334 |
|
| 2009 |
Stewart DS, Husain SS, Miller KW, Forman SA. MTS-Etomidate Selectively Reacts Within the GABAA Receptor Etomidate Binding Site Biophysical Journal. 96: 487a-488a. DOI: 10.1016/J.Bpj.2008.12.2516 |
0.37 |
|
| 2009 |
Marius P, Miller KW, Williamson PT. Probing Molecular Interactions in Biological Membranes by Solid-State NMR Biophysical Journal. 96: 207a. DOI: 10.1016/J.Bpj.2008.12.1841 |
0.31 |
|
| 2008 |
Ho C, Shanmugasundararaj S, Miller KW, Malinowski SA, Cook AC, Slater SJ. Interaction of anesthetics with the Rho GTPase regulator Rho GDP dissociation inhibitor. Biochemistry. 47: 9540-52. PMID 18702520 DOI: 10.1021/Bi800544D |
0.308 |
|
| 2007 |
Williamson PT, Verhoeven A, Miller KW, Meier BH, Watts A. The conformation of acetylcholine at its target site in the membrane-embedded nicotinic acetylcholine receptor. Proceedings of the National Academy of Sciences of the United States of America. 104: 18031-6. PMID 17989232 DOI: 10.1073/Pnas.0704785104 |
0.359 |
|
| 2006 |
Husain SS, Nirthanan S, Ruesch D, Solt K, Cheng Q, Li GD, Arevalo E, Olsen RW, Raines DE, Forman SA, Cohen JB, Miller KW. Synthesis of trifluoromethylaryl diazirine and benzophenone derivatives of etomidate that are potent general anesthetics and effective photolabels for probing sites on ligand-gated ion channels. Journal of Medicinal Chemistry. 49: 4818-25. PMID 16884293 DOI: 10.1021/Jm051207B |
0.361 |
|
| 2005 |
Arevalo E, Chiara DC, Forman SA, Cohen JB, Miller KW. Gating-enhanced accessibility of hydrophobic sites within the transmembrane region of the nicotinic acetylcholine receptor's {delta}-subunit. A time-resolved photolabeling study. The Journal of Biological Chemistry. 280: 13631-40. PMID 15664985 DOI: 10.1074/Jbc.M413911200 |
0.321 |
|
| 2004 |
Das J, Addona GH, Sandberg WS, Husain SS, Stehle T, Miller KW. Identification of a general anesthetic binding site in the diacylglycerol-binding domain of protein kinase Cdelta. The Journal of Biological Chemistry. 279: 37964-72. PMID 15234976 DOI: 10.1074/Jbc.M405137200 |
0.302 |
|
| 2004 |
Ziebell MR, Nirthanan S, Husain SS, Miller KW, Cohen JB. Identification of binding sites in the nicotinic acetylcholine receptor for [3H]azietomidate, a photoactivatable general anesthetic. The Journal of Biological Chemistry. 279: 17640-9. PMID 14761946 DOI: 10.1074/Jbc.M313886200 |
0.342 |
|
| 2003 |
Husain SS, Ziebell MR, Ruesch D, Hong F, Arevalo E, Kosterlitz JA, Olsen RW, Forman SA, Cohen JB, Miller KW. 2-(3-Methyl-3H-diaziren-3-yl)ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate: a derivative of the stereoselective general anesthetic etomidate for photolabeling ligand-gated ion channels. Journal of Medicinal Chemistry. 46: 1257-65. PMID 12646036 DOI: 10.1021/Jm020465V |
0.331 |
|
| 2003 |
Addona GH, Sandermann H, Kloczewiak MA, Miller KW. Low chemical specificity of the nicotinic acetylcholine receptor sterol activation site. Biochimica Et Biophysica Acta. 1609: 177-82. PMID 12543379 DOI: 10.1016/S0005-2736(02)00685-5 |
0.319 |
|
| 2002 |
Miller KW. The nature of sites of general anaesthetic action. British Journal of Anaesthesia. 89: 17-31. PMID 12173229 DOI: 10.1093/Bja/Aef167 |
0.366 |
|
| 2001 |
Williamson PT, Watts JA, Addona GH, Miller KW, Watts A. Dynamics and orientation of N+(CD3)3-bromoacetylcholine bound to its binding site on the nicotinic acetylcholine receptor. Proceedings of the National Academy of Sciences of the United States of America. 98: 2346-51. PMID 11226242 DOI: 10.1073/Pnas.031361698 |
0.364 |
|
| 2001 |
Chiara DC, Kloczewiak MA, Addona GH, Yu JA, Cohen JB, Miller KW. Site of resting state inhibition of the nicotinic acetylcholine receptor by a hydrophobic inhibitor. Biochemistry. 40: 296-304. PMID 11141083 DOI: 10.1021/Bi0021481 |
0.331 |
|
| 2000 |
Pratt MB, Husain SS, Miller KW, Cohen JB. Identification of sites of incorporation in the nicotinic acetylcholine receptor of a photoactivatible general anesthetic. The Journal of Biological Chemistry. 275: 29441-51. PMID 10859324 DOI: 10.1074/Jbc.M004710200 |
0.32 |
|
| 1999 |
Husain SS, Forman SA, Kloczewiak MA, Addona GH, Olsen RW, Pratt MB, Cohen JB, Miller KW. Synthesis and properties of 3-(2-hydroxyethyl)-3-n-pentyldiazirine, a photoactivable general anesthetic. Journal of Medicinal Chemistry. 42: 3300-7. PMID 10464016 DOI: 10.1021/Jm9806300 |
0.352 |
|
| 1999 |
Addona GH, Kloczewiak MA, Miller KW. Time-resolved photolabeling of membrane proteins: application to the nicotinic acetylcholine receptor. Analytical Biochemistry. 267: 135-40. PMID 9918665 DOI: 10.1006/Abio.1998.2959 |
0.344 |
|
| 1998 |
Miller KW, Addona GH, Kloczewiak MA. Approaches to proving there are general anesthetic sites on ligand gated ion channels. Toxicology Letters. 100: 139-47. PMID 10049134 DOI: 10.1016/S0378-4274(98)00178-7 |
0.324 |
|
| 1998 |
Williamson PT, Watts J, Gröbner G, Miller KW, Watts A. Solid state NMR studies of ligands bound to the nicotinic acetylcholine receptor. Biochemical Society Transactions. 26: S297. PMID 9766016 DOI: 10.1042/Bst026S297 |
0.305 |
|
| 1998 |
Williamson PT, Gröbner G, Spooner PJ, Miller KW, Watts A. Probing the agonist binding pocket in the nicotinic acetylcholine receptor: a high-resolution solid-state NMR approach. Biochemistry. 37: 10854-9. PMID 9692976 DOI: 10.1021/Bi980390Q |
0.375 |
|
| 1998 |
Addona GH, Sandermann H, Kloczewiak MA, Husain SS, Miller KW. Where does cholesterol act during activation of the nicotinic acetylcholine receptor? Biochimica Et Biophysica Acta. 1370: 299-309. PMID 9545586 DOI: 10.1016/S0005-2736(97)00280-0 |
0.333 |
|
| 1997 |
Rankin SE, Addona GH, Kloczewiak MA, Bugge B, Miller KW. The cholesterol dependence of activation and fast desensitization of the nicotinic acetylcholine receptor. Biophysical Journal. 73: 2446-55. PMID 9370438 DOI: 10.1016/S0006-3495(97)78273-0 |
0.337 |
|
| 1995 |
Raines DE, Rankin SE, Miller KW. General anesthetics modify the kinetics of nicotinic acetylcholine receptor desensitization at clinically relevant concentrations Anesthesiology. 82: 276-287. PMID 7832311 DOI: 10.1097/00000542-199501000-00033 |
0.365 |
|
| 1994 |
Abadji V, Raines DE, Dalton LA, Miller KW. Lipid-protein interactions and protein dynamics in vesicles containing the nicotinic acetylcholine receptor: a study with ethanol. Biochimica Et Biophysica Acta. 1194: 25-34. PMID 8075138 DOI: 10.1016/0005-2736(94)90199-6 |
0.306 |
|
| 1994 |
Wu G, Miller KW. Ethanol enhances agonist-induced fast desensitization in nicotinic acetylcholine receptors. Biochemistry. 33: 9085-91. PMID 8049210 DOI: 10.1021/Bi00197A009 |
0.312 |
|
| 1994 |
Wu G, Raines DE, Miller KW. A hydrophobic inhibitor of the nicotinic acetylcholine receptor acts on the resting state. Biochemistry. 33: 15375-15381. PMID 7803400 DOI: 10.1021/Bi00255A018 |
0.305 |
|
| 1994 |
Raines DE, Rankin SE, Miller KW. ISOFLURANEʼS ACTIONS ON THE NICOTINIC ACETYLCHOLINE RECEPTOR DEPEND ON THE COMPOSITION OF THE LIPID BILAYER Anesthesiology. 81: A885. DOI: 10.1097/00000542-199409001-00884 |
0.318 |
|
| 1993 |
Baenziger JE, Miller KW, Rothschild KJ. Fourier transform infrared difference spectroscopy of the nicotinic acetylcholine receptor: Evidence for specific protein structural changes upon desensitization Biochemistry. 32: 5448-5454. PMID 8499448 DOI: 10.1021/Bi00071A022 |
0.706 |
|
| 1993 |
de Armendi AJ, Tonner PH, Bugge B, Miller KW. Barbiturate action is dependent on the conformational state of the acetylcholine receptor. Anesthesiology. 79: 1033-41. PMID 8238981 DOI: 10.1097/00000542-199311000-00022 |
0.344 |
|
| 1993 |
Alifimoff J, Bugge B, Forman S, Miller K. Stereoselectivity of Channel Inhibition by Secondary Alkanol Enantiomers at Nicotinic Acetylcholine Receptors Anesthesiology. 79: 122-128. DOI: 10.1097/00000542-199307000-00018 |
0.348 |
|
| 1993 |
Rankin SE, Raines DE, Dalton LA, Miller KW. Chapter 9 Functional aspects of acetylcholine receptor-lipid interactions New Comprehensive Biochemistry. 25: 213-229. DOI: 10.1016/S0167-7306(08)60238-0 |
0.324 |
|
| 1992 |
Baenziger JE, Miller KW, McCarthy MP, Rothschild KJ. Probing conformational changes in the nicotinic acetylcholine receptor by Fourier transform infrared difference spectroscopy Biophysical Journal. 62: 64-66. PMID 1600101 DOI: 10.1016/S0006-3495(92)81780-0 |
0.703 |
|
| 1992 |
Baenziger JE, Miller KW, Rotschild KJ. Incorporation of the nicotinic acetylcholine receptor into planar multilamellar films: Characterization by fluorescence and Fourier transform infrared difference spectroscopy Biophysical Journal. 61: 983-992. PMID 1581507 DOI: 10.1016/S0006-3495(92)81905-7 |
0.611 |
|
| 1991 |
Miller KW, Wood SC, Forman SA, Bugge B, Hill WA, Abadji V. The nicotinic acetylcholine receptor in its membrane environment. Annals of the New York Academy of Sciences. 625: 600-15. PMID 1711816 DOI: 10.1111/J.1749-6632.1991.Tb33895.X |
0.316 |
|
| 1990 |
Forman SA, Miller KW. Molecular sites of anesthetic action in postsynaptic nicotinic membranes. Trends in Pharmacological Sciences. 10: 447-52. PMID 2692257 DOI: 10.1016/S0165-6147(89)80009-4 |
0.365 |
|
| 1990 |
Dodson BA, Urh RR, Miller KW. Relative potencies for barbiturate binding to the Torpedo acetylcholine receptor. British Journal of Pharmacology. 101: 710-4. PMID 1963806 DOI: 10.1111/J.1476-5381.1990.Tb14145.X |
0.318 |
|
| 1989 |
Forman SA, Miller KW. Procaine rapidly inactivates acetylcholine receptors from Torpedo and competes with agonist for inhibition sites. Biochemistry. 28: 1678-85. PMID 2719927 DOI: 10.1021/Bi00430A038 |
0.33 |
|
| 1989 |
Alifimoff JK, Bugge B, Forman S, Miller KW. NONSTEREOSELECTIVE BLOCK OF NICOTINIC ACETYLCHOLINE RECEPTOR CHANNELS BY ENANTIOMERS OF GENERAL ANESTHETICS Anesthesiology. 71: A317. DOI: 10.1097/00000542-198909001-00317 |
0.308 |
|
| 1988 |
Forman SA, Miller KW. High acetylcholine concentrations cause rapid inactivation before fast desensitization in nicotinic acetylcholine receptors from Torpedo. Biophysical Journal. 54: 149-58. PMID 3416024 DOI: 10.1016/S0006-3495(88)82939-4 |
0.349 |
|
| 1987 |
Forman SA, Firestone LL, Miller KW. Is agonist self-inhibition at the nicotinic acetylcholine receptor a nonspecific action? Biochemistry. 26: 2807-14. PMID 3038165 DOI: 10.1021/Bi00384A023 |
0.354 |
|
| 1987 |
Leibel WS, Firestone LL, Legler DC, Braswell LM, Miller KW. Two pools of cholesterol in acetylcholine receptor-rich membranes from Torpedo. Biochimica Et Biophysica Acta. 897: 249-60. PMID 2434127 DOI: 10.1016/0005-2736(87)90421-4 |
0.31 |
|
| 1986 |
Firestone L, Sauter J-, Braswell L, Miller K. Actions of General Anesthetics on Acetylcholine Receptor-rich Membranes from Torpedo californica Anesthesiology. 64: 694-702. DOI: 10.1097/00000542-198606000-00004 |
0.388 |
|
| 1984 |
Braswell LM, Miller KW, Sauter JF. Pressure reversal of the action of octanol on postsynaptic membranes from Torpedo. British Journal of Pharmacology. 83: 305-11. PMID 6487895 DOI: 10.1111/J.1476-5381.1984.Tb10147.X |
0.377 |
|
| 1982 |
Miller KW, Sauter JF, Braswell LM. A stereoselective pentobarbital binding site in cholinergic membranes from Torpedo californica. Biochemical and Biophysical Research Communications. 105: 659-66. PMID 7092877 DOI: 10.1016/0006-291X(82)91485-1 |
0.336 |
|
| 1975 |
Gait D, Miller KW, Paton WD, Smith EB, Welch B. The redistribution of vascular bubbles in multiple dives. Undersea Biomedical Research. 2: 42-50. PMID 1181707 |
0.545 |
|
| 1973 |
Miller KW, Paton WD, Smith RA, Smith EB. The pressure reversal of general anesthesia and the critical volume hypothesis. Molecular Pharmacology. 9: 131-43. PMID 4711696 |
0.581 |
|
| 1972 |
Miller KW, Paton WD, Smith EB, Smith RA. Physicochemical approaches to the mode of action of general anesthetics. Anesthesiology. 36: 339-51. PMID 5020643 |
0.558 |
|
| 1971 |
Lever MJ, Miller KW, Paton WD, Smith EB. Pressure reversal of anaesthesia. Nature. 231: 368-71. PMID 4931002 |
0.573 |
|
| 1971 |
Griffiths HB, Miller KW, Paton WD, Smith EB. On the role of separated gas in decompression procedures. Proceedings of the Royal Society of London. Series B, Biological Sciences. 178: 389-406. PMID 4398676 |
0.547 |
|
| 1967 |
Miller KW, Paton WD, Smith EB. The anaesthetic pressures of certain fluorine-containing gases. British Journal of Anaesthesia. 39: 910-8. PMID 6082560 |
0.578 |
|
| 1967 |
Miller KW, Paton WD, Streett WB, Smith EB. Animals at very high pressures of helium and neon. Science (New York, N.Y.). 157: 97-8. PMID 6026676 |
0.575 |
|
| 1966 |
Lever MJ, Miller KW, Paton WD, Smith EB. Experiments on the genesis of bubbles as a result of rapid decompression. The Journal of Physiology. 184: 964-9. PMID 5912215 |
0.563 |
|
| 1965 |
Miller KW, Paton WD, Smith EB. Site of action of general anaesthetics. Nature. 206: 574-7. PMID 5890773 |
0.591 |
|
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