Minhong Yan - Publications

Affiliations: 
Molecular Oncology Genentech, Inc., San Francisco, CA, United States 

36/61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Kedage V, Ellerman D, Fei M, Liang WC, Zhang G, Cheng E, Zhang J, Chen Y, Huang H, Lee WP, Wu Y, Yan M. CLEC5a-directed bispecific antibody for effective cellular phagocytosis. Mabs. 14: 2040083. PMID 35293277 DOI: 10.1080/19420862.2022.2040083  0.334
2020 Chen Y, Paluch M, Zorn JA, Rajan S, Leonard B, Estevez A, Brady J, Chiu H, Phung W, Famili A, Yan M, Ciferri C, Matsumoto ML, Lazar GA, Crowell S, et al. Targeted IgMs agonize ocular targets with extended vitreal exposure. Mabs. 12: 1818436. PMID 32936727 DOI: 10.1080/19420862.2020.1818436  0.351
2020 Zhou Y, Fei M, Zhang G, Liang WC, Lin W, Wu Y, Piskol R, Ridgway J, McNamara E, Huang H, Zhang J, Oh J, Patel JM, Jakubiak D, Lau J, ... ... Yan M, et al. Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP. Immunity. PMID 32049051 DOI: 10.1016/J.Immuni.2020.01.014  0.446
2020 Kedage V, Ellerman D, Chen Y, Liang WC, Borneo J, Wu Y, Yan M. Harnessing MerTK agonism for targeted therapeutics. Mabs. 12: 1685832. PMID 31852344 DOI: 10.1080/19420862.2019.1685832  0.382
2018 Radojcic V, Paz K, Chung J, Du J, Perkey ET, Flynn R, Ivcevic S, Zaiken M, Friedman A, Yan M, Pletneva MA, Sarantopoulos S, Siebel CW, Blazar BR, Maillard I. Notch signaling mediated by Delta-like1/4 ligands controls the pathogenesis of chronic graft-versus-host disease in mice. Blood. PMID 30181175 DOI: 10.1182/Blood-2018-03-841155  0.326
2016 Ola R, Dubrac A, Han J, Zhang F, Fang JS, Larrivée B, Lee M, Urarte AA, Kraehling JR, Genet G, Hirschi KK, Sessa WC, Canals FV, Graupera M, Yan M, et al. PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia. Nature Communications. 7: 13650. PMID 27897192 DOI: 10.1038/Ncomms13650  0.394
2015 Zhang G, Brady J, Liang WC, Wu Y, Henkemeyer M, Yan M. EphB4 forward signalling regulates lymphatic valve development. Nature Communications. 6: 6625. PMID 25865237 DOI: 10.1038/Ncomms7625  0.36
2015 Wang W, Yu S, Zimmerman G, Wang Y, Myers J, Yu VW, Huang D, Huang X, Shim J, Huang Y, Xin W, Qiao P, Yan M, Xin W, Scadden DT, et al. Notch Receptor-Ligand Engagement Maintains Hematopoietic Stem Cell Quiescence and Niche Retention. Stem Cells (Dayton, Ohio). 33: 2280-93. PMID 25851125 DOI: 10.1002/Stem.2031  0.317
2014 Zhou L, Wang W, Zimmerman G, Myers J, Huang Y, Yu VW, Huang D, Yu S, Wang Y, Huang X, Shim J, Yan M, Lowe J, Xin W, Stanley P, et al. Loss of Notch Receptor-Ligand Engagement Leads to Increased Hematopoietic Stem and Progenitor Cell Egress and Mobilization Blood. 124: 652-652. DOI: 10.1182/Blood.V124.21.652.652  0.448
2013 Chen H, Brady Ridgway J, Sai T, Lai J, Warming S, Chen H, Roose-Girma M, Zhang G, Shou W, Yan M. Context-dependent signaling defines roles of BMP9 and BMP10 in embryonic and postnatal development. Proceedings of the National Academy of Sciences of the United States of America. 110: 11887-92. PMID 23812757 DOI: 10.1073/Pnas.1306074110  0.402
2013 Ebens CL, Chung J, Koch U, Tran IT, Sandy-Sloat AR, Friedman A, Blazar BR, Reddy P, Yan M, Siebel CW, Radtke F, Maillard I. Delta-Like Notch Ligands Expressed By Host Non-Hematopoietic Radioresistant Cells Regulate Graft-Versus-Host Disease and Extrathymic T Cell Development After Bone Marrow Transplantation Blood. 122: 2003-2003. DOI: 10.1182/Blood.V122.21.2003.2003  0.378
2011 Niessen K, Zhang G, Ridgway JB, Chen H, Kolumam G, Siebel CW, Yan M. The Notch1-Dll4 signaling pathway regulates mouse postnatal lymphatic development. Blood. 118: 1989-97. PMID 21700774 DOI: 10.1182/Blood-2010-11-319129  0.352
2011 Tran IT, Sandy AR, Carulli A, Shan GT, Radojcic V, Friedman A, Shelton A, Samuelson LC, Yan M, Siebel CW, Maillard I. In Vivo Blockade of Individual Notch Ligands and Receptors Provides a New Targeted Therapeutic Approach In Graft-Versus-Host Disease Blood. 118: 819-819. DOI: 10.1182/Blood.V118.21.819.819  0.357
2010 Wu Y, Cain-Hom C, Choy L, Hagenbeek TJ, de Leon GP, Chen Y, Finkle D, Venook R, Wu X, Ridgway J, Schahin-Reed D, Dow GJ, Shelton A, Stawicki S, Watts RJ, ... ... Yan M, et al. Therapeutic antibody targeting of individual Notch receptors. Nature. 464: 1052-7. PMID 20393564 DOI: 10.1038/Nature08878  0.441
2010 Yan M, Callahan CA, Beyer JC, Allamneni KP, Zhang G, Ridgway JB, Niessen K, Plowman GD. Chronic DLL4 blockade induces vascular neoplasms. Nature. 463: E6-7. PMID 20147986 DOI: 10.1038/Nature08751  0.323
2010 Niessen K, Zhang G, Ridgway JB, Chen H, Yan M. ALK1 signaling regulates early postnatal lymphatic vessel development. Blood. 115: 1654-61. PMID 19903896 DOI: 10.1182/Blood-2009-07-235655  0.391
2007 Yan M, Plowman GD. Delta-like 4/Notch signaling and its therapeutic implications. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 7243-6. PMID 18094402 DOI: 10.1158/1078-0432.Ccr-07-1393  0.315
2006 Ridgway J, Zhang G, Wu Y, Stawicki S, Liang WC, Chanthery Y, Kowalski J, Watts RJ, Callahan C, Kasman I, Singh M, Chien M, Tan C, Hongo JA, de Sauvage F, ... ... Yan M, et al. Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis. Nature. 444: 1083-7. PMID 17183323 DOI: 10.1038/Nature05313  0.372
2005 Hymowitz SG, Patel DR, Wallweber HJ, Runyon S, Yan M, Yin J, Shriver SK, Gordon NC, Pan B, Skelton NJ, Kelley RF, Starovasnik MA. Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding. The Journal of Biological Chemistry. 280: 7218-27. PMID 15542592 DOI: 10.1074/Jbc.M411714200  0.427
2004 Newton K, French DM, Yan M, Frantz GD, Dixit VM. Myodegeneration in EDA-A2 Transgenic Mice Is Prevented by XEDAR Deficiency Molecular and Cellular Biology. 24: 1608-1613. PMID 14749376 DOI: 10.1128/Mcb.24.4.1608-1613.2004  0.536
2003 Hymowitz SG, Compaan DM, Yan M, Wallweber HJA, Dixit VM, Starovasnik MA, De Vos AM. The Crystal Structures of EDA-A1 and EDA-A2: Splice Variants with Distinct Receptor Specificity Structure. 11: 1513-1520. PMID 14656435 DOI: 10.1016/J.Str.2003.11.009  0.52
2003 Gordon NC, Pan B, Hymowitz SG, Yin J, Kelley RF, Cochran AG, Yan M, Dixit VM, Fairbrother WJ, Starovasnik MA. BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site. Biochemistry. 42: 5977-83. PMID 12755599 DOI: 10.1021/Bi034017G  0.575
2003 Seshasayee D, Valdez P, Yan M, Dixit VM, Tumas D, Grewal IS. Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor Immunity. 18: 279-288. PMID 12594954 DOI: 10.1016/S1074-7613(03)00025-6  0.642
2002 Kayagaki N, Yan M, Seshasayee D, Wang H, Lee W, French DM, Grewal IS, Cochran AG, Gordon NC, Yin J, Starovasnik MA, Dixit VM. BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2. Immunity. 17: 515-24. PMID 12387744 DOI: 10.1016/S1074-7613(02)00425-9  0.613
2002 Moreno E, Yan M, Basler K. Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily. Current Biology : Cb. 12: 1263-8. PMID 12176339 DOI: 10.1016/S0960-9822(02)00954-5  0.397
2002 Yan M, Zhang Z, Brady JR, Schilbach S, Fairbrother WJ, Dixit VM. Identification of a novel death domain-containing adaptor molecule for ectodysplasin-A receptor that is mutated in crinkled mice Current Biology. 12: 409-413. PMID 11882293 DOI: 10.1016/S0960-9822(02)00687-5  0.594
2001 Zhao H, Yan M, Wang H, Erickson S, Grewal IS, Dixit VM. Impaired c-Jun amino terminal kinase activity and T cell differentiation in death receptor 6-deficient mice Journal of Experimental Medicine. 194: 1441-1448. PMID 11714751 DOI: 10.1084/Jem.194.10.1441  0.562
2001 Yan M, Brady JR, Chan B, Lee WP, Hsu B, Harless S, Cancro M, Grewal IS, Dixit VM. Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency Current Biology. 11: 1547-1552. PMID 11591325 DOI: 10.1016/S0960-9822(01)00481-X  0.633
2001 Yan M, Wang H, Chan B, Roose-Girma M, Erickson S, Baker T, Tumas D, Grewal IS, Dixit VM. Activation and accumulation of B cells in TACI-deficient mice Nature Immunology. 2: 638-643. PMID 11429549 DOI: 10.1038/89790  0.624
2001 Wang H, Marsters SA, Baker T, Chan B, Lee WP, Fu L, Tumas D, Yan M, Dixit VM, Ashkenazi A, Grewal IS. TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice. Nature Immunology. 2: 632-7. PMID 11429548 DOI: 10.1038/89782  0.59
2000 Yan M, Wang LC, Hymowitz SG, Schilbach S, Lee J, Goddard A, De Vos AM, Gao WQ, Dixit VM. Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors Science. 290: 523-527. PMID 11039935 DOI: 10.1126/Science.290.5491.523  0.543
2000 Marsters SA, Yan M, Pitti RM, Haas PE, Dixit VM, Ashkenazi A. Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI. Current Biology : Cb. 10: 785-8. PMID 10898980 DOI: 10.1016/S0960-9822(00)00566-2  0.619
2000 Yan M, Marsters SA, Grewal IS, Wang H, Ashkenazi A, Dixit VM. Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity. Nature Immunology. 1: 37-41. PMID 10881172 DOI: 10.1038/76889  0.615
1999 Zhang Q, Siebert R, Yan M, Hinzmann B, Cui X, Xue L, Rakestraw KM, Naeve CW, Beckmann G, Weisenburger DD, Sanger WG, Nowotny H, Vesely M, Callet-Bauchu E, Salles G, et al. Inactivating mutations and overexpression of BCL 10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32) Nature Genetics. 22: 63-68. PMID 10319863 DOI: 10.1038/8767  0.553
1999 Yan M, Lee J, Schilbach S, Goddard A, Dixit V. mE10, a novel caspase recruitment domain-containing proapoptotic molecule. The Journal of Biological Chemistry. 274: 10287-92. PMID 10187815 DOI: 10.1074/Jbc.274.15.10287  0.524
1998 Gerber HP, McMurtrey A, Kowalski J, Yan M, Keyt BA, Dixit V, Ferrara N. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. The Journal of Biological Chemistry. 273: 30336-43. PMID 9804796 DOI: 10.1074/Jbc.273.46.30336  0.522
Low-probability matches (unlikely to be authored by this person)
2014 Kamath AV, Yip V, Gupta P, Boswell CA, Bumbaca D, Haughney P, Castro J, Tsai SP, Pacheco G, Ross S, Yan M, Damico-Beyer LA, Khawli L, Shen BQ. Dose dependent pharmacokinetics, tissue distribution, and anti-tumor efficacy of a humanized monoclonal antibody against DLL4 in mice. Mabs. 6: 1631-7. PMID 25484068 DOI: 10.4161/Mabs.36107  0.299
2011 Lee S, Maeda M, Wilson AE, Li M, Ishikawa Y, Judd AM, Sakurai N, Fiorini E, Radtke F, Yan M, Macdonald HR, Chen C, Maeda T. LRF Maintains HSC Homeostasis by Preventing Lymphoid-Primed LT-HSCs From Excessive Differentiation Blood. 118: 44-44. DOI: 10.1182/blood.v118.21.44.44  0.296
2016 Radojcic V, Flynn RP, Chung J, Du J, Perkey E, Paz K, Zaiken M, Friedman A, Yan M, Siebel CW, Blazar BR, Maillard I. Notch Signaling Mediated By Dll1/4 Notch Ligands Controls the Pathogenesis of Both Multi-Organ System Non-Sclerodermatous and Sclerodermatous Chronic Graft-Versus-Host Disease Blood. 128: 805-805. DOI: 10.1182/Blood.V128.22.805.805  0.295
2010 Lee S, Li M, Maeda M, Sakurai N, Ishikawa Y, Radtke F, Yan M, Macdonald HR, Maeda T. Notch Repression by LRF Is Necessary for the Maintenance of Adult Hematopoietic Stem Cell Pool. Blood. 116: 2633-2633. DOI: 10.1182/blood.v116.21.2633.2633  0.29
2013 Tran IT, Sandy AR, Carulli AJ, Ebens C, Chung J, Shan GT, Radojcic V, Friedman A, Gridley T, Shelton A, Reddy P, Samuelson LC, Yan M, Siebel CW, Maillard I. Blockade of individual Notch ligands and receptors controls graft-versus-host disease. The Journal of Clinical Investigation. 123: 1590-604. PMID 23454750 DOI: 10.1172/Jci65477  0.288
2017 Chung J, Ebens CL, Perkey E, Radojcic V, Koch U, Scarpellino L, Tong A, Allen F, Wood S, Feng J, Friedman A, Granadier D, Tran IT, Chai Q, Onder L, ... Yan M, et al. Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands. The Journal of Clinical Investigation. PMID 28319044 DOI: 10.1172/Jci89535  0.287
2014 Chung J, Ebens CL, Radojcic V, Koch U, Friedman A, Tran IT, Chai Q, Onder L, Yan M, Reddy P, Blazar BR, Ludewig B, Siebel CW, Radtke F, Maillard I. Delta-like Ligands Expressed By Stromal Cells in Secondary Lymphoid Organs Deliver an Early Pulse of Notch Signaling and Drive T Cell Pathogenicity in Acute Graft-Versus-Host Disease Blood. 124: 841-841. DOI: 10.1182/Blood.V124.21.841.841  0.282
2015 Gama-Norton L, Ferrando E, Ruiz-Herguido C, Liu Z, Guiu J, Islam AB, Lee SU, Yan M, Guidos CJ, López-Bigas N, Maeda T, Espinosa L, Kopan R, Bigas A. Notch signal strength controls cell fate in the haemogenic endothelium. Nature Communications. 6: 8510. PMID 26465397 DOI: 10.1038/ncomms9510  0.271
2011 Yin N, Zhang N, Lal G, Xu J, Yan M, Ding Y, Bromberg JS. Lymphangiogenesis is required for pancreatic islet inflammation and diabetes. Plos One. 6: e28023. PMID 22132197 DOI: 10.1371/journal.pone.0028023  0.259
2019 Thackaberry EA, Zhou Y, Zuch de Zafra CL, Fuh G, Lee CV, Sanowar S, Ridgway JB, Kusi AM, Farman C, Booler H, Sheinson D, Rasmussen CA, Miller PE, Wakshull E, Yan M, et al. Rapid Development of Glaucoma Via ITV Nonselective ANGPT 1/2 Antibody: A Potential Role for ANGPT/TIE2 Signaling in Primate Aqueous Humor Outflow. Investigative Ophthalmology & Visual Science. 60: 4097-4108. PMID 31574535 DOI: 10.1167/Iovs.18-26349  0.246
2022 Vollmar BS, Fei M, Liang WC, Bravo DD, Wang J, Yu L, Corr N, Zhang G, McNamara E, Masih S, Chee E, Shin G, Ohri R, Leipold DD, Wu C, ... ... Yan M, et al. PEGylation of anti-MerTK Antibody Modulates Ocular Biodistribution. Bioconjugate Chemistry. PMID 36153839 DOI: 10.1021/acs.bioconjchem.2c00276  0.231
2023 Bravo DD, Shi Y, Sheu A, Liang WC, Lin W, Wu Y, Yan M, Wang J. A Real-Time Image-Based Efferocytosis Assay for the Discovery of Functionally Inhibitory Anti-MerTK Antibodies. Journal of Immunology (Baltimore, Md. : 1950). PMID 36881873 DOI: 10.4049/jimmunol.2200597  0.223
2015 Wood S, Feng J, Chung J, Radojcic V, Sandy-Sloat AR, Friedman A, Shelton A, Yan M, Siebel CW, Bishop DK, Maillard I. Transient blockade of delta-like Notch ligands prevents allograft rejection mediated by cellular and humoral mechanisms in a mouse model of heart transplantation. Journal of Immunology (Baltimore, Md. : 1950). 194: 2899-908. PMID 25687759 DOI: 10.4049/Jimmunol.1402034  0.214
1996 Zanke BW, Rubie EA, Winnett E, Chan J, Randall S, Parsons M, Boudreau K, McInnis M, Yan M, Templeton DJ, Woodgett JR. Mammalian mitogen-activated protein kinase pathways are regulated through formation of specific kinase-activator complexes. The Journal of Biological Chemistry. 271: 29876-81. PMID 8939929 DOI: 10.1074/Jbc.271.47.29876  0.212
2018 Jabs M, Rose AJ, Lehmann LH, Taylor J, Moll I, Sijmonsma TP, Herberich SE, Sauer SW, Poschet G, Federico G, Mogler C, Weis EM, Augustin HG, Yan M, Gretz N, et al. Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart. Circulation. PMID 29353241 DOI: 10.1161/Circulationaha.117.029733  0.208
2013 Lee SU, Maeda M, Ishikawa Y, Li SM, Wilson A, Jubb AM, Sakurai N, Weng L, Fiorini E, Radtke F, Yan M, Macdonald HR, Chen CC, Maeda T. LRF-mediated Dll4 repression in erythroblasts is necessary for hematopoietic stem cell maintenance. Blood. 121: 918-29. PMID 23134786 DOI: 10.1182/blood-2012-03-418103  0.196
2011 Yan M. Therapeutic promise and challenges of targeting DLL4/NOTCH1. Vascular Cell. 3: 17. PMID 21824400 DOI: 10.1186/2045-824X-3-17  0.164
2011 Yan M. Therapeutic promise and challenges of targeting DLL4/NOTCH1 Vascular Cell. 3. DOI: 10.1186/2045-824X-3-17  0.164
2015 Couch J, Zhang G, Beyer J, Zuch de Zafra C, Gupta P, Kamath A, Lewin-Koh N, Tarrant J, Allamneni K, Cain G, Yee S, Ross S, Cook R, Tsai SP, Ruppel J, ... ... Yan M, et al. Balancing efficacy and safety of an anti-DLL4 antibody through pharmacokinetic modulation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26589434 DOI: 10.1158/1078-0432.CCR-15-1380  0.151
2020 Oh SA, Wu D, Cheung J, Navarro A, Xiong H, Cubas R, Totpal K, Chiu H, Wu Y, Comps-Agrar L, Leader AM, Merad M, Roose-Germa M, Warming S, Yan M, et al. PD-L1 expression by dendritic cells is a key regulator of T-cell immunity in cancer Nature Cancer. 1: 681-691. DOI: 10.1038/s43018-020-0075-x  0.148
2003 Seanor KL, Cross JV, Nguyen SM, Yan M, Templeton DJ. Reactive quinones differentially regulate SAPK/JNK and p38/mHOG stress kinases. Antioxidants & Redox Signaling. 5: 103-13. PMID 12626122 DOI: 10.1089/152308603321223595  0.141
2020 Oh SA, Wu DC, Cheung J, Navarro A, Xiong H, Cubas R, Totpal K, Chiu H, Wu Y, Comps-Agrar L, Leader AM, Merad M, Roose-Germa M, Warming S, Yan M, et al. PD-L1 expression by dendritic cells is a key regulator of T-cell immunity in cancer. Nature Cancer. 1: 681-691. PMID 35122038 DOI: 10.1038/s43018-020-0075-x  0.137
2016 Gama-Norton L, Ferrando E, Ruiz-Herguido C, Liu Z, Guiu J, Islam AB, Lee SU, Yan M, Guidos CJ, López-Bigas N, Maeda T, Espinosa L, Kopan R, Bigas A. Corrigendum: Notch signal strength controls cell fate in the haemogenic endothelium. Nature Communications. 7: 10978. PMID 26939771 DOI: 10.1038/ncomms10978  0.09
2022 Agard NJ, Zhang G, Ridgeway J, Dicara DM, Chu PY, Ohri R, Sanowar S, Vernes JM, Chi H, Zhang J, Holz E, Paluch M, He G, Benson Y, Zhang J, ... ... Yan M, et al. Direct Tie2 Agonists Stabilize Vasculature for the Treatment of Diabetic Macular Edema. Translational Vision Science & Technology. 11: 27. PMID 36255358 DOI: 10.1167/tvst.11.10.27  0.088
2019 Fu Y, Yan M, Yang H, Ma X, Guo J. Palm-Sized Uric Acid Test Lab Powered by Smartphone for Proactive Gout Management. Ieee Transactions On Biomedical Circuits and Systems. PMID 31226083 DOI: 10.1109/TBCAS.2019.2922674  0.043
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