David J Robbins - Publications

Affiliations: 
Experimental and Molecular Medicine Geisel School of Medicine at Dartmouth, Hanover, NH, United States 

95/187 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, ... Robbins DJ, et al. The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling. Nature Communications. 14: 6173. PMID 37798301 DOI: 10.1038/s41467-023-41836-z  0.303
2023 Spencer ZT, Ng VH, Benchabane H, Siddiqui GS, Duwadi D, Maines B, Bryant JM, Schwarzkopf A, Yuan K, Kassel SN, Mishra A, Pimentel A, Lebensohn AM, Rohatgi R, Gerber SA, Robbins DJ, et al. The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6. Nature Communications. 14: 6174. PMID 37798281 DOI: 10.1038/s41467-023-41843-0  0.314
2023 Kassel S, Hanson AJ, Benchabane H, Saito-Diaz K, Cabel CR, Goldsmith L, Taha M, Kanuganti A, Ng VH, Xu G, Ye F, Picker J, Port F, Boutros M, Weiss VL, ... Robbins DJ, et al. USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling. Science Signaling. 16: eabn8372. PMID 36749823 DOI: 10.1126/scisignal.abn8372  0.331
2022 Yang F, Wynn DT, Shen C, Ayad NG, Robbins DJ. Multiprotein GLI Transcriptional Complexes as Therapeutic Targets in Cancer. Life (Basel, Switzerland). 12. PMID 36556332 DOI: 10.3390/life12121967  0.355
2022 Wynn DT, Rodriguez-Blanco J, Long J, Yang F, Shen C, Fei D, Tang HY, Hanson D, Robbins DJ. Protein arginine methyltransferase 5 regulates SHH-subgroup medulloblastoma progression. Neuro-Oncology Advances. 4: vdac144. PMID 36299796 DOI: 10.1093/noajnl/vdac144  0.321
2022 Yang F, Rodriguez-Blanco J, Long J, Swiderska-Syn M, Wynn DT, Li B, Shen C, Nayak A, Ban Y, Sun X, Suter RK, McCrea HJ, Capobianco AJ, Ayad NG, Robbins DJ. A druggable UHRF1/DNMT1/GLI complex regulates Sonic hedgehog dependent tumor growth. Molecular Cancer Research : McR. PMID 35925047 DOI: 10.1158/1541-7786.MCR-22-0182  0.348
2022 Shen C, Nayak A, Neitzel LR, Yang F, Li B, Williams CH, Hong CC, Ahmed Y, Lee E, Robbins DJ. The Casein kinase 1α agonist pyrvinium attenuates Wnt-mediated CK1α degradation via interaction with the E3 ubiquitin ligase component Cereblon. The Journal of Biological Chemistry. 102227. PMID 35780831 DOI: 10.1016/j.jbc.2022.102227  0.307
2021 Shen C, Nayak A, Neitzel LR, Adams AA, Silver-Isenstadt M, Sawyer LM, Benchabane H, Wang H, Bunnag N, Li B, Wynn DT, Yang F, Garcia-Contreras M, Williams CH, Dakshanamurthy S, ... Robbins DJ, et al. The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling. Nature Communications. 12: 5263. PMID 34489457 DOI: 10.1038/s41467-021-25634-z  0.369
2021 Alvarez-Trotta A, Guerrant W, Astudillo L, Lahiry M, Diluvio G, Shersher E, Kaneku H, Robbins DJ, Orton D, Capobianco AJ. Pharmacological disruption of the Notch1 transcriptional complex inhibits tumor growth by selectively targeting cancer stem cells. Cancer Research. PMID 33820800 DOI: 10.1158/0008-5472.CAN-20-3611  0.393
2020 Alvarez-Trotta A, Wang Z, Shersher E, Li B, Long J, Lohse I, Wahlestedt C, El-Rifai W, Robbins DJ, Capobianco AJ. The bromodomain inhibitor IBET-151 attenuates vismodegib-resistant esophageal adenocarcinoma growth through reduction of GLI signaling. Oncotarget. 11: 3174-3187. PMID 32913560 DOI: 10.18632/Oncotarget.27699  0.458
2020 Shen C, Nayak A, Melendez RA, Wynn DT, Jackson J, Lee E, Ahmed Y, Robbins DJ. Casein Kinase 1α as a Regulator of Wnt-Driven Cancer. International Journal of Molecular Sciences. 21. PMID 32824859 DOI: 10.3390/Ijms21165940  0.479
2020 Anthony CC, Robbins DJ, Ahmed Y, Lee E. Nuclear Regulation of Wnt/β-Catenin Signaling: It's a Complex Situation. Genes. 11. PMID 32759724 DOI: 10.3390/Genes11080886  0.399
2019 Shen C, Li B, Astudillo L, Deutscher MP, Cobb MH, Capobianco AJ, Lee E, Robbins DJ. The CK1α Activator Pyrvinium Enhances the Catalytic Efficiency (/) of CK1α. Biochemistry. PMID 31820934 DOI: 10.1021/Acs.Biochem.9B00891  0.388
2019 Samaranayake GJ, Troccoli CI, Zhang L, Huynh M, Jayaraj CJ, Ji D, McPherson L, Onishi Y, Nguyen DM, Robbins DJ, Karbaschi M, Cooke MS, Barrientos A, Kool ET, Rai P. The existence of MTH1-independent 8-oxodGTPase activity in cancer cells as a compensatory mechanism against on-target effects of MTH1 inhibitors. Molecular Cancer Therapeutics. PMID 31744893 DOI: 10.1158/1535-7163.Mct-19-0437  0.383
2019 McPherson LA, Troccoli CI, Ji D, Bowles AE, Gardiner ML, Mohsen MG, Nagathihalli NS, Nguyen DM, Robbins DJ, Merchant NB, Kool ET, Rai P, Ford JM. Increased MTH1-specific 8-oxodGTPase activity is a hallmark of cancer in colon, lung and pancreatic tissue. Dna Repair. 102644. PMID 31311767 DOI: 10.1016/J.Dnarep.2019.102644  0.391
2019 Lu H, Bhat AA, Peng D, Chen Z, Zhu S, Hong J, Maacha S, Yan J, Robbins DJ, Washington MK, Belkhiri A, El-Rifai W. APE1 upregulates MMP-14 via redox-sensitive ARF6-mediated recycling to promote cell invasion of esophageal adenocarcinoma. Cancer Research. PMID 31308045 DOI: 10.1158/0008-5472.Can-19-0237  0.321
2019 Penas C, Maloof ME, Stathias V, Long J, Tan SK, Mier J, Fang Y, Valdes C, Rodriguez-Blanco J, Chiang CM, Robbins DJ, Liebl DJ, Lee JK, Hatten ME, Clarke J, et al. Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis. Nature Communications. 10: 3028. PMID 31292434 DOI: 10.1038/S41467-019-10799-5  0.376
2019 Cabel CR, Alizadeh E, Robbins DJ, Ahmed Y, Lee E, Thorne CA. Single-Cell Analyses Confirm the Critical Role of LRP6 for Wnt Signaling in APC-Deficient Cells. Developmental Cell. 49: 827-828. PMID 31211991 DOI: 10.1016/J.Devcel.2019.05.039  0.444
2019 Taylor R, Long J, Yoon JW, Childs R, Sylvestersen KB, Nielsen ML, Leong KF, Iannaccone S, Walterhouse DO, Robbins DJ, Iannaccone P. Regulation of GLI1 by cis DNA elements and epigenetic marks. Dna Repair. 79: 10-21. PMID 31085420 DOI: 10.1016/J.Dnarep.2019.04.011  0.377
2019 Neitzel LR, Spencer ZT, Nayak A, Cselenyi CS, Benchabane H, Youngblood CQ, Zouaoui A, Ng V, Stephens L, Hann T, Patton JG, Robbins D, Ahmed Y, Lee E. Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway. Mechanisms of Development. PMID 30904594 DOI: 10.1016/J.Mod.2019.03.002  0.455
2019 Lu H, Bhat AA, Peng D, Chen Z, Zhu S, Hong J, Maacha S, Robbins D, Belkhiri A, El-Rifai W. Abstract 157: APE1 upregulates MMP-14 to promote invasion of esophageal adenocarcinoma via redox-sensitive ARF6-mediated recycling Cancer Research. 79: 157-157. DOI: 10.1158/1538-7445.Am2019-157  0.343
2018 Robbins DJ, Rodriguez-Blanco J, Li B, Shen C, Orton D, Collins SA, Kasahara N, Ayad N, McCrea HJ, Roussel MF, Weiss WA, Capobianco AJ, Long J, Yang F. A CK1α activator penetrates the brain, and shows efficacy against drug-resistant metastatic medulloblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30487124 DOI: 10.1158/1078-0432.Ccr-18-1319  0.344
2018 Saito-Diaz K, Benchabane H, Tiwari A, Tian A, Li B, Thompson JJ, Hyde AS, Sawyer LM, Jodoin JN, Santos E, Lee LA, Coffey RJ, Beauchamp RD, Williams CS, Kenworthy AK, ... Robbins DJ, et al. APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway. Developmental Cell. 44: 566-581.e8. PMID 29533772 DOI: 10.1016/J.Devcel.2018.02.013  0.436
2018 Pei X, Chan H, Zhang L, Wang C, Robbins D, Capobianco T, Bai F. Abstract P2-08-01: Loss of function of Brca1 or Gata3 induces basal-like breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P2-08-01  0.371
2018 Tan SK, Penas C, Chiang C, Robbins D, Ayad N. Abstract 4138: CK1δ-BRD4 pathway as novel therapeutic target for SHH subtype of medulloblastoma Tumor Biology. DOI: 10.1158/1538-7445.Am2018-4138  0.334
2018 Rodriguez-Blanco J, Pednekar L, Penas C, Li B, Martin V, Long J, Lee E, Weiss W, Rodriguez C, Mehrdad N, Nguyen D, Ayad N, Rai P, Capobianco A, Robbins D. MBRS-64. SURPRISING ROLE FOR WNT SIGNALING IN SONIC HEDGEHOG DRIVEN MEDULLOBLASTOMA Neuro-Oncology. 20: i142-i142. DOI: 10.1093/Neuonc/Noy059.508  0.413
2017 Rodriguez-Blanco J, Pednekar L, Penas C, Li B, Martin V, Long J, Lee E, Weiss WA, Rodriguez C, Mehrdad N, Nguyen DM, Ayad NG, Rai P, Capobianco AJ, Robbins DJ. Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma. Oncogene. PMID 28714964 DOI: 10.1038/Onc.2017.232  0.438
2017 Li B, Orton D, Neitzel LR, Astudillo L, Shen C, Long J, Chen X, Kirkbride KC, Doundoulakis T, Guerra ML, Zaias J, Fei DL, Rodriguez-Blanco J, Thorne C, Wang Z, ... ... Robbins DJ, et al. Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors. Science Signaling. 10. PMID 28655862 DOI: 10.1126/Scisignal.Aak9916  0.46
2017 Jin K, Zhou W, Han X, Wang Z, Li B, Jeffries S, Tao W, Robbins DJ, Capobianco AJ. p300-mediated acetylation of the Notch effector transcription factor Maml-1 recruits NACK to initiate Notch-dependent transcription. Cancer Research. PMID 28625977 DOI: 10.1158/0008-5472.Can-16-3156  0.36
2017 Han X, Ranganathan P, Tzimas C, Weaver KL, Jin K, Astudillo L, Zhou W, Zhu X, Li B, Robbins DJ, Capobianco AJ. Notch Represses Transcription by PRC2 Recruitment to the Ternary Complex. Molecular Cancer Research : McR. PMID 28584023 DOI: 10.1158/1541-7786.Mcr-17-0241  0.326
2017 Scott A, Bai F, Chan HL, Liu S, Slingerland JM, Robbins DJ, Capobianco AJ, Pei XH. p16 loss rescues functional decline of Brca1-deficient mammary stem cells. Cell Cycle (Georgetown, Tex.). 0. PMID 28278054 DOI: 10.1080/15384101.2017.1295185  0.325
2017 Rodriguez-Blanco J, Pednekar L, Penas C, Li B, Martin V, Long J, Lee E, Weiss W, Rodriguez C, Merhdad N, Nguyen D, Ayad N, Rai P, Capobianco A, Robbins DJ. PDTM-03. SURPRISING ROLE FOR WNT SIGNALING IN Trp53-MUTANT SHH MEDULLOBLASTOMA Neuro-Oncology. 19: vi190-vi190. DOI: 10.1093/Neuonc/Nox168.768  0.399
2016 Scott A, Bai F, Chan HL, Liu S, Ma J, Slingerland JM, Robbins DJ, Capobianco AJ, Pei XH. p16INK4a suppresses BRCA1-deficient mammary tumorigenesis. Oncotarget. PMID 27811360 DOI: 10.18632/Oncotarget.13015  0.342
2016 Liu S, Lam Chan H, Bai F, Ma J, Scott A, Robbins DJ, Capobianco AJ, Zhu P, Pei XH. Gata3 restrains B cell proliferation and cooperates with p18INK4c to repress B cell lymphomagenesis. Oncotarget. PMID 27588406 DOI: 10.18632/Oncotarget.11746  0.328
2016 Broadus MR, Chen TW, Neitzel LR, Ng VH, Jodoin JN, Lee LA, Salic A, Robbins DJ, Capobianco AJ, Patton JG, Huppert SS, Lee E. Identification of a Paralog-Specific Notch1 Intracellular Domain Degron. Cell Reports. PMID 27210761 DOI: 10.1016/J.Celrep.2016.04.070  0.412
2016 Astudillo L, da Silva TG, Wang Z, Han X, Jin K, VanWye J, Zhu X, Weaver KL, Oashi T, Lopes PE, Orton D, Neitzel LR, Lee E, Landgraf R, Robbins DJ, et al. The small molecule IMR-1 inhibits the Notch transcriptional activation complex to suppress tumorigenesis. Cancer Research. PMID 27197169 DOI: 10.1158/0008-5472.Can-16-0061  0.438
2016 Castellanos J, Srinivasan S, Honnenahally K, Shi C, VanSaun M, Robbins D, Merchant N, Nagathihalli N. Abstract 2618: Oncogenic mutant KRAS modulates CREB activation through MEK-ERK and AKT signaling in pancreatic cancer Cancer Research. 76: 2618-2618. DOI: 10.1158/1538-7445.Am2016-2618  0.472
2015 Li B, Giambelli C, Tang B, Winterbottom E, Long J, Jin K, Wang Z, Liang Fei D, Nguyen DM, Athar M, Wang B, Subbarayan PR, Wang L, Rai P, Ardalan B, ... ... Robbins DJ, et al. Arsenic Attenuates GLI Signaling, Increasing or Decreasing its Transcriptional Program in a Context Dependent Manner. Molecular Pharmacology. PMID 26573582 DOI: 10.1124/Mol.115.100867  0.476
2015 Long J, Winterbottom E, Robbins DJ. Sonic Hedgehog: a lipid speciated hormone? Oncotarget. 6: 19340-1. PMID 26305721 DOI: 10.18632/Oncotarget.4969  0.349
2015 Winterbottom EF, Fei DL, Koestler DC, Giambelli C, Wika E, Capobianco AJ, Lee E, Marsit CJ, Karagas MR, Robbins DJ. GLI3 Links Environmental Arsenic Exposure and Human Fetal Growth. Ebiomedicine. 2: 536-43. PMID 26288817 DOI: 10.1016/J.Ebiom.2015.04.019  0.325
2015 Farzan SF, Robbins DJ. Quantitative Immunoblotting of Endogenous Hedgehog Pathway Components. Methods in Molecular Biology (Clifton, N.J.). 1322: 93-104. PMID 26179042 DOI: 10.1007/978-1-4939-2772-2_9  0.396
2015 Penas C, Govek EE, Fang Y, Ramachandran V, Daniel M, Wang W, Maloof ME, Rahaim RJ, Bibian M, Kawauchi D, Finkelstein D, Han JL, Long J, Li B, Robbins DJ, et al. Casein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis. Cell Reports. 11: 249-60. PMID 25843713 DOI: 10.1016/J.Celrep.2015.03.016  0.406
2015 Long J, Tokhunts R, Old WM, Houel S, Rodgriguez-Blanco J, Singh S, Schilling N, Capobianco AJ, Ahn NG, Robbins DJ. Identification of a family of fatty-acid-speciated sonic hedgehog proteins, whose members display differential biological properties. Cell Reports. 10: 1280-7. PMID 25732819 DOI: 10.1016/J.Celrep.2015.01.058  0.737
2015 Lindley LE, Curtis KM, Sanchez-Mejias A, Rieger ME, Robbins DJ, Briegel KJ. The WNT-controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineage. Development (Cambridge, England). 142: 893-904. PMID 25655704 DOI: 10.1242/Dev.110403  0.386
2015 Allen BK, Stathias V, Maloof ME, Vidovic D, Winterbottom EF, Capobianco AJ, Clarke J, Schurer S, Robbins DJ, Ayad NG. Epigenetic pathways and glioblastoma treatment: insights from signaling cascades. Journal of Cellular Biochemistry. 116: 351-63. PMID 25290986 DOI: 10.1002/Jcb.24990  0.442
2015 Patel A, Burton DG, Halvorsen K, Balkan W, Reiner T, Perez-Stable C, Cohen A, Munoz A, Giribaldi MG, Singh S, Robbins DJ, Nguyen DM, Rai P. MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways. Oncogene. 34: 2586-96. PMID 25023700 DOI: 10.1038/Onc.2014.195  0.419
2015 Pei X, Bai F, Chan HL, Scott A, Smith MD, Fan C, Herschkowitz JI, Perou CM, Livingstone AS, Robbins DJ, Capobianco AJ. Abstract P4-05-01: Genetic analysis of the role of Brca1 in suppression of basal-like breast cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P4-05-01  0.377
2015 Allen BK, Stathias V, Maloof ME, Vidovic D, Winterbottom EF, Capobianco AJ, Clarke J, Schurer S, Robbins DJ, Ayad NG. Editor's Choice: Epigenetic Pathways and Glioblastoma Treatment: Insights from Signaling Cascades Journal of Cellular Biochemistry. 116: iii. DOI: 10.1002/Jcb.25034  0.371
2014 Long J, Li B, Rodriguez-Blanco J, Pastori C, Volmar CH, Wahlestedt C, Capobianco A, Bai F, Pei XH, Ayad NG, Robbins DJ. The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers. The Journal of Biological Chemistry. 289: 35494-502. PMID 25355313 DOI: 10.1074/Jbc.M114.595348  0.52
2014 Bai F, Chan HL, Scott A, Smith MD, Fan C, Herschkowitz JI, Perou CM, Livingstone AS, Robbins DJ, Capobianco AJ, Pei XH. BRCA1 suppresses epithelial-to-mesenchymal transition and stem cell dedifferentiation during mammary and tumor development. Cancer Research. 74: 6161-72. PMID 25239453 DOI: 10.1158/0008-5472.Can-14-1119  0.417
2014 Wang Z, Da Silva TG, Jin K, Han X, Ranganathan P, Zhu X, Sanchez-Mejias A, Bai F, Li B, Fei DL, Weaver K, Carpio RV, Moscowitz AE, Koshenkov VP, Sanchez L, ... ... Robbins DJ, et al. Notch signaling drives stemness and tumorigenicity of esophageal adenocarcinoma. Cancer Research. 74: 6364-74. PMID 25164006 DOI: 10.1158/0008-5472.Can-14-2051  0.457
2014 Weaver KL, Alves-Guerra MC, Jin K, Wang Z, Han X, Ranganathan P, Zhu X, DaSilva T, Liu W, Ratti F, Demarest RM, Tzimas C, Rice M, Vasquez-Del Carpio R, Dahmane N, ... Robbins DJ, et al. NACK is an integral component of the Notch transcriptional activation complex and is critical for development and tumorigenesis. Cancer Research. 74: 4741-51. PMID 25038227 DOI: 10.1158/0008-5472.Can-14-1547  0.414
2014 Li B, Flaveny CA, Giambelli C, Fei DL, Han L, Hang BI, Bai F, Pei XH, Nose V, Burlingame O, Capobianco AJ, Orton D, Lee E, Robbins DJ. Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis. Plos One. 9: e101969. PMID 25003333 DOI: 10.1371/Journal.Pone.0101969  0.421
2014 Li B, Fei DL, Flaveny CA, Dahmane N, Baubet V, Wang Z, Bai F, Pei XH, Rodriguez-Blanco J, Hang B, Orton D, Han L, Wang B, Capobianco AJ, Lee E, ... Robbins DJ, et al. Pyrvinium attenuates Hedgehog signaling downstream of smoothened. Cancer Research. 74: 4811-21. PMID 24994715 DOI: 10.1158/0008-5472.Can-14-0317  0.515
2014 Sverrisson EF, Zens MS, Fei DL, Andrews A, Schned A, Robbins D, Kelsey KT, Li H, DiRenzo J, Karagas MR, Seigne JD. Clinicopathological correlates of Gli1 expression in a population-based cohort of patients with newly diagnosed bladder cancer. Urologic Oncology. 32: 539-45. PMID 24856810 DOI: 10.1016/J.Urolonc.2014.03.006  0.414
2014 Busch AM, Galimberti F, Nehls KE, Roengvoraphoj M, Sekula D, Li B, Guo Y, Direnzo J, Fiering SN, Spinella MJ, Robbins DJ, Memoli VA, Freemantle SJ, Dmitrovsky E. All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched. Cancer Biology & Therapy. 15: 463-72. PMID 24496080 DOI: 10.4161/Cbt.27821  0.63
2014 You M, Varona-Santos J, Singh S, Robbins DJ, Savaraj N, Nguyen DM. Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro. The Journal of Thoracic and Cardiovascular Surgery. 147: 508-16. PMID 24094913 DOI: 10.1016/J.Jtcvs.2013.08.035  0.451
2014 Patel A, Halvorsen K, Balkan W, Cohen A, Reiner T, Robbins D, Nguyen D, Rai P. Abstract B14: Human Mut T homolog 1 (MTH1) as a novel facilitator of KRAS-driven lung cancer Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-B14  0.42
2014 Singh S, Nguyen DM, Capobianco AJ, Robbins DJ. Abstract 1951: Role of embryonic signaling pathways in lung cancer Cancer Research. 74: 1951-1951. DOI: 10.1158/1538-7445.Am2014-1951  0.511
2014 Rodriguez-Blanco J, Bin L, Martin V, Lee E, Rodriguez C, Capobianco A, Robbins DJ. SC-28 * NOVEL INHIBITORS ON HEDGEHOG PATHWAY TO PREVENT MEDULLOBLASTOMA RELAPSE Neuro-Oncology. 16: v203-v203. DOI: 10.1093/Neuonc/Nou275.28  0.433
2013 Srivastava RK, Li C, Chaudhary SC, Ballestas ME, Elmets CA, Robbins DJ, Matalon S, Deshane JS, Afaq F, Bickers DR, Athar M. Unfolded protein response (UPR) signaling regulates arsenic trioxide-mediated macrophage innate immune function disruption. Toxicology and Applied Pharmacology. 272: 879-87. PMID 23954561 DOI: 10.1016/J.Taap.2013.08.004  0.36
2013 Rodriguez-Blanco J, Schilling NS, Tokhunts R, Giambelli C, Long J, Liang Fei D, Singh S, Black KE, Wang Z, Galimberti F, Bejarano PA, Elliot S, Glassberg MK, Nguyen DM, Lockwood WW, ... ... Robbins DJ, et al. The hedgehog processing pathway is required for NSCLC growth and survival. Oncogene. 32: 2335-45. PMID 22733134 DOI: 10.1038/Onc.2012.243  0.777
2013 Pochi SR, Doshi N, Han X, Wang Z, Capobianco A, Robbins D, Ardalan B. Abstract 4019: Regulatory role of Gli motifs in thymidylate synthase expression . Cancer Research. 73: 4019-4019. DOI: 10.1158/1538-7445.Am2013-4019  0.407
2013 You M, Santos JV, Robbins DJ, Savaraj N, Nguyen DM. Abstract 3246: Pharmacologic targeting of the Hedgehog (HH) signal transduction pathway significantly suppresses growth of malignant pleural mesothelioma (MPM) and non-small cell lung cancer (NSCLC) cells in vitro. Cancer Research. 73: 3246-3246. DOI: 10.1158/1538-7445.Am2013-3246  0.539
2013 Singh S, Robbins D, Capobianco AJ, Nguyen DM. Abstract 2645: Role of embryonic signaling pathways in lung cancer. Cancer Research. 73: 2645-2645. DOI: 10.1158/1538-7445.Am2013-2645  0.513
2012 Robbins DJ, Fei DL, Riobo NA. The Hedgehog signal transduction network. Science Signaling. 5: re6. PMID 23074268 DOI: 10.1126/Scisignal.2002906  0.436
2012 Galimberti F, Busch AM, Chinyengetere F, Ma T, Sekula D, Memoli VA, Dragnev KH, Liu F, Johnson KC, Guo Y, Freemantle SJ, Andrew AS, Greninger P, Robbins DJ, Settleman J, et al. Response to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations. International Journal of Oncology. 41: 1751-61. PMID 22923130 DOI: 10.3892/Ijo.2012.1599  0.604
2012 Fei DL, Sanchez-Mejias A, Wang Z, Flaveny C, Long J, Singh S, Rodriguez-Blanco J, Tokhunts R, Giambelli C, Briegel KJ, Schulz WA, Gandolfi AJ, Karagas M, Zimmers TA, Jorda M, ... ... Robbins DJ, et al. Hedgehog signaling regulates bladder cancer growth and tumorigenicity. Cancer Research. 72: 4449-58. PMID 22815529 DOI: 10.1158/0008-5472.Can-11-4123  0.778
2012 Hang BI, Thorne CA, Robbins DJ, Huppert SS, Lee LA, Lee E. Screening for small molecule inhibitors of embryonic pathways: sometimes you gotta crack a few eggs. Bioorganic & Medicinal Chemistry. 20: 1869-77. PMID 22261025 DOI: 10.1016/J.Bmc.2011.12.044  0.352
2012 Wang Z, Ranganathan P, Koshenkov V, Bai F, Li B, Fei DL, Livingstone A, Franceschi D, Martell J, Robbins DJ, Capobianco AJ. Abstract 3336: The role of Notch signaling in esophageal adenocarcinoma Cancer Research. 72: 3336-3336. DOI: 10.1158/1538-7445.Am2012-3336  0.527
2012 Sverrisson E, Zens M, Fei D, Schned A, Robbins D, Kelsey K, Karagas M, Seigne J. 889 Clinicopathological Correlates Of Gli1 Expression In A Population Based Cohort Of Patients With Newly Diagnosed Bladder Cancer The Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.984  0.302
2011 Thorne CA, Lafleur B, Lewis M, Hanson AJ, Jernigan KK, Weaver DC, Huppert KA, Chen TW, Wichaidit C, Cselenyi CS, Tahinci E, Meyers KC, Waskow E, Orton D, Salic A, ... ... Robbins DJ, et al. A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts. Journal of Biomolecular Screening. 16: 995-1006. PMID 21859680 DOI: 10.1177/1087057111416657  0.407
2011 Singh S, Wang Z, Liang Fei D, Black KE, Goetz JA, Tokhunts R, Giambelli C, Rodriguez-Blanco J, Long J, Lee E, Briegel KJ, Bejarano PA, Dmitrovsky E, Capobianco AJ, Robbins DJ. Hedgehog-producing cancer cells respond to and require autocrine Hedgehog activity. Cancer Research. 71: 4454-63. PMID 21565978 DOI: 10.1158/0008-5472.Can-10-2313  0.776
2011 Vasquez-Del Carpio R, Kaplan FM, Weaver KL, VanWye JD, Alves-Guerra MC, Robbins DJ, Capobianco AJ. Assembly of a Notch transcriptional activation complex requires multimerization. Molecular and Cellular Biology. 31: 1396-408. PMID 21245387 DOI: 10.1128/Mcb.00360-10  0.348
2011 Singh S, Wang Z, Giambelli C, Long J, Briegel KJ, Bejarano PA, Capobianco AJ, Robbins DJ. Abstract LB-430: Hedgehog signaling is required for the survival and tumorigenicity of cancer cells. Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-430  0.515
2011 Saeed A, Ngyuen D, Glassberg M, Koniaris L, Zimmers T, Robbins D, Lally B. The Influence of Latino Ethnicity on the Outcomes for Patients with Non-small Cell Lung Cancer: An Analysis of the Survival, Epidemiology, and End Results (SEER) Database International Journal of Radiation Oncology*Biology*Physics. 81: S597. DOI: 10.1016/J.Ijrobp.2011.06.1120  0.322
2010 Xiao C, Ogle SA, Schumacher MA, Schilling N, Tokhunts RA, Orr-Asman MA, Miller ML, Robbins DJ, Hollande F, Zavros Y. Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G1252-65. PMID 20847300 DOI: 10.1152/Ajpgi.00512.2009  0.756
2010 Fei DL, Li H, Kozul CD, Black KE, Singh S, Gosse JA, DiRenzo J, Martin KA, Wang B, Hamilton JW, Karagas MR, Robbins DJ. Activation of Hedgehog signaling by the environmental toxicant arsenic may contribute to the etiology of arsenic-induced tumors. Cancer Research. 70: 1981-8. PMID 20179202 DOI: 10.1158/0008-5472.Can-09-2898  0.356
2010 Farzan SF, Ogden SK, Robbins DJ. Quantitative insight into models of Hedgehog signal transduction Fly. 4: 141-144. PMID 20081354 DOI: 10.4161/Fly.4.2.10927  0.437
2010 Tokhunts R, Singh S, Chu T, D'Angelo G, Baubet V, Goetz JA, Huang Z, Yuan Z, Ascano M, Zavros Y, Thérond PP, Kunes S, Dahmane N, Robbins DJ. The full-length unprocessed hedgehog protein is an active signaling molecule. The Journal of Biological Chemistry. 285: 2562-8. PMID 19920144 DOI: 10.1074/Jbc.M109.078626  0.755
2009 Farzan SF, Stegman MA, Ogden SK, Ascano M, Black KE, Tacchelly O, Robbins DJ. A quantification of pathway components supports a novel model of Hedgehog signal transduction. The Journal of Biological Chemistry. 284: 28874-84. PMID 19717563 DOI: 10.1074/Jbc.M109.041608  0.347
2009 Singh S, Tokhunts R, Baubet V, Goetz JA, Huang ZJ, Schilling NS, Black KE, MacKenzie TA, Dahmane N, Robbins DJ. Sonic hedgehog mutations identified in holoprosencephaly patients can act in a dominant negative manner. Human Genetics. 125: 95-103. PMID 19057928 DOI: 10.1007/S00439-008-0599-0  0.738
2008 Ogden SK, Fei DL, Schilling NS, Ahmed YF, Hwa J, Robbins DJ. G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling. Nature. 456: 967-70. PMID 18987629 DOI: 10.1038/Nature07459  0.321
2008 Farzan SF, Ascano M, Ogden SK, Sanial M, Brigui A, Plessis A, Robbins DJ. Costal2 functions as a kinesin-like protein in the hedgehog signal transduction pathway. Current Biology : Cb. 18: 1215-20. PMID 18691888 DOI: 10.1016/J.Cub.2008.07.026  0.332
2008 Li N, Singh S, Cherukuri P, Li H, Yuan Z, Ellisen LW, Wang B, Robbins D, DiRenzo J. Reciprocal intraepithelial interactions between TP63 and hedgehog signaling regulate quiescence and activation of progenitor elaboration by mammary stem cells. Stem Cells (Dayton, Ohio). 26: 1253-64. PMID 18292212 DOI: 10.1634/Stemcells.2007-0691  0.311
2008 Tafe LJ, Robbins DJ, Fei DL, Srivastava A. M1953 GLI-1 Expression Suggests That Sonic Hedgehog Signaling May Be Involved in the Pathogenesis of Barrett's Esophagus Gastroenterology. 134: A-438. DOI: 10.1016/S0016-5085(08)62046-6  0.351
2007 Robbins DJ, Hebrok M. Hedgehogs: la dolce vita. Workshop on Hedgehog-Gli Signaling in Cancer and Stem Cells. Embo Reports. 8: 451-5. PMID 17431408 DOI: 10.1038/Sj.Embor.7400959  0.304
2007 Ma Y, Fiering S, Black C, Liu X, Yuan Z, Memoli VA, Robbins DJ, Bentley HA, Tsongalis GJ, Demidenko E, Freemantle SJ, Dmitrovsky E. Transgenic cyclin E triggers dysplasia and multiple pulmonary adenocarcinomas. Proceedings of the National Academy of Sciences of the United States of America. 104: 4089-94. PMID 17360482 DOI: 10.1073/Pnas.0606537104  0.537
2007 Yuan Z, Goetz JA, Singh S, Ogden SK, Petty WJ, Black CC, Memoli VA, Dmitrovsky E, Robbins DJ. Frequent requirement of hedgehog signaling in non-small cell lung carcinoma. Oncogene. 26: 1046-55. PMID 16909105 DOI: 10.1038/Sj.Onc.1209860  0.622
2006 Ogden SK, Casso DJ, Ascano M, Yore MM, Kornberg TB, Robbins DJ. Smoothened regulates activator and repressor functions of Hedgehog signaling via two distinct mechanisms. The Journal of Biological Chemistry. 281: 7237-43. PMID 16423832 DOI: 10.1074/Jbc.M510169200  0.349
2005 Robbins D, Goetz J, Yuan Z, Stegman M. Inhibitors of the Hedgehog Signal Transduction Pathway Current Cancer Therapy Reviews. 1: 277-288. DOI: 10.2174/157339405774574243  0.408
2004 Ogden SK, Ascano M, Stegman MA, Robbins DJ. Regulation of Hedgehog signaling: a complex story. Biochemical Pharmacology. 67: 805-14. PMID 15104233 DOI: 10.1016/J.Bcp.2004.01.002  0.323
2003 Ogden SK, Ascano M, Stegman MA, Suber LM, Hooper JE, Robbins DJ. Identification of a functional interaction between the transmembrane protein Smoothened and the kinesin-related protein Costal2. Current Biology : Cb. 13: 1998-2003. PMID 14614827 DOI: 10.1016/J.Cub.2003.10.004  0.364
2003 Krebs O, Schreiner CM, Scott WJ, Bell SM, Robbins DJ, Goetz JA, Alt H, Hawes N, Wolf E, Favor J. Replicated anterior zeugopod (raz): a polydactylous mouse mutant with lowered Shh signaling in the limb bud. Development (Cambridge, England). 130: 6037-47. PMID 14597572 DOI: 10.1242/Dev.00861  0.347
2002 Alvarez J, Sohn P, Zeng X, Doetschman T, Robbins DJ, Serra R. TGFbeta2 mediates the effects of hedgehog on hypertrophic differentiation and PTHrP expression. Development (Cambridge, England). 129: 1913-24. PMID 11934857  0.313
Low-probability matches (unlikely to be authored by this person)
2012 Saeed AM, Toonkel R, Glassberg MK, Nguyen D, Hu JJ, Zimmers TA, Robbins DJ, Koniaris LG, Lally BE. The influence of Hispanic ethnicity on nonsmall cell lung cancer histology and patient survival: an analysis of the Survival, Epidemiology, and End Results database. Cancer. 118: 4495-501. PMID 22528551 DOI: 10.1002/Cncr.26686  0.295
2004 Tsonis PA, Vergara MN, Spence JR, Madhavan M, Kramer EL, Call MK, Santiago WG, Vallance JE, Robbins DJ, Del Rio-Tsonis K. A novel role of the hedgehog pathway in lens regeneration. Developmental Biology. 267: 450-61. PMID 15013805 DOI: 10.1016/J.Ydbio.2003.12.005  0.295
2004 Ascano M, Robbins DJ. An intramolecular association between two domains of the protein kinase Fused is necessary for Hedgehog signaling. Molecular and Cellular Biology. 24: 10397-405. PMID 15542847 DOI: 10.1128/Mcb.24.23.10397-10405.2004  0.294
2002 Ascano M, Nybakken KE, Sosinski J, Stegman MA, Robbins DJ. The carboxyl-terminal domain of the protein kinase fused can function as a dominant inhibitor of hedgehog signaling. Molecular and Cellular Biology. 22: 1555-66. PMID 11839821 DOI: 10.1128/Mcb.22.5.1555-1566.2002  0.29
2008 Farzan SF, Singh S, Schilling NS, Robbins DJ. The adventures of sonic hedgehog in development and repair. III. Hedgehog processing and biological activity. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G844-9. PMID 18239057 DOI: 10.1152/ajpgi.00564.2007  0.289
2002 Goetz JA, Suber LM, Zeng X, Robbins DJ. Sonic Hedgehog as a mediator of long-range signaling. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 24: 157-65. PMID 11835280 DOI: 10.1002/bies.10056  0.285
1997 Robbins DJ, Nybakken KE, Kobayashi R, Sisson JC, Bishop JM, Thérond PP. Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2. Cell. 90: 225-34. PMID 9244297 DOI: 10.1016/S0092-8674(00)80331-1  0.285
2005 Bell SM, Schreiner CM, Goetz JA, Robbins DJ, Scott WJ. Shh signaling in limb bud ectoderm: potential role in teratogen-induced postaxial ectrodactyly. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 233: 313-25. PMID 15858818 DOI: 10.1002/dvdy.20409  0.275
2017 Winterbottom EF, Koestler DC, Fei DL, Wika E, Capobianco AJ, Marsit CJ, Karagas MR, Robbins DJ. The aquaglyceroporin AQP9 contributes to the sex-specific effects of in utero arsenic exposure on placental gene expression. Environmental Health : a Global Access Science Source. 16: 59. PMID 28615018 DOI: 10.1186/S12940-017-0267-8  0.275
2019 Meng J, Banerjee S, Zhang L, Sindberg G, Moidunny S, Li B, Robbins DJ, Girotra M, Segura B, Ramakrishnan S, Roy S. Opioids Impair Intestinal Epithelial Repair in HIV-Infected Humanized Mice. Frontiers in Immunology. 10: 2999. PMID 32010125 DOI: 10.3389/Fimmu.2019.02999  0.268
1997 Burczak JD, Wilkinson FE, Robbins DJ. Impact of genomics on diagnostic medicine Drug Development Research. 41: 193-204. DOI: 10.1002/(Sici)1098-2299(199707/08)41:3/4<193::Aid-Ddr9>3.0.Co;2-G  0.266
2019 Winterbottom EF, Moroishi Y, Halchenko Y, Armstrong DA, Beach PJ, Nguyen QP, Capobianco AJ, Ayad NG, Marsit CJ, Li Z, Karagas MR, Robbins DJ. Prenatal arsenic exposure alters the placental expression of multiple epigenetic regulators in a sex-dependent manner. Environmental Health : a Global Access Science Source. 18: 18. PMID 30819207 DOI: 10.1186/S12940-019-0455-9  0.263
2015 Clarke R, Kim W, Groff B, Abujarour R, Robinson M, Huang X, Sahaf N, Raynel S, Rezner B, Robbins D, Guerrettaz L, Shoemaker D, Valamehr B. A Platform for the Scalable Derivation of Genetically-Enhanced T and NK Lymphocytes from Naive Human Induced Pluripotent Stem Cells for Cancer Immunotherapy Blood. 126: 2364-2364. DOI: 10.1182/Blood.V126.23.2364.2364  0.257
2006 Caserta TM, Kommagani R, Yuan Z, Robbins DJ, Mercer CA, Kadakia MP. p63 overexpression induces the expression of Sonic Hedgehog. Molecular Cancer Research : McR. 4: 759-68. PMID 17050669 DOI: 10.1158/1541-7786.Mcr-05-0149  0.256
2017 Li B, Lee E, Robbins DJ. Casein kinase1α activators, a precision weapon for CRC. Oncotarget. 8: 96462-96463. PMID 29228537 DOI: 10.18632/Oncotarget.21892  0.255
2015 Huang X, Lan W, Parone P, Clarke R, Abujarour R, Robinson M, Meza M, Raynel S, Rezner B, Robbins D, Lee TT, Shoemaker D, Valamehr B. Human Induced Pluripotent Stem Cells Incorporating Safe Harbor Loci Integrated Inducible Suicide Systems for Use in the Application of Cellular Therapeutics Blood. 126: 3237-3237. DOI: 10.1182/Blood.V126.23.3237.3237  0.254
2021 Shersher E, Lahiry M, Alvarez-Trotta A, Diluvio G, Robbins DJ, Shiekhattar R, Capobianco AJ. NACK and INTEGRATOR act coordinately to activate Notch-mediated transcription in tumorigenesis. Cell Communication and Signaling : Ccs. 19: 96. PMID 34551776 DOI: 10.1186/s12964-021-00776-1  0.248
2014 Nadeau KC, Li Z, Farzan S, Koestler D, Robbins D, Fei DL, Malipatlolla M, Maecker H, Enelow R, Korrick S, Karagas MR. In utero arsenic exposure and fetal immune repertoire in a US pregnancy cohort. Clinical Immunology (Orlando, Fla.). 155: 188-97. PMID 25229165 DOI: 10.1016/J.Clim.2014.09.004  0.247
2016 Bjordahl R, Clarke R, Gaidarova S, Groff B, Rogers P, Moreno S, Abujarour R, Bonello G, Lee TT, Lan W, Burrascano M, Bauer M, Robinson M, Sasaki J, Kim W, ... Robbins D, et al. Off-the-Shelf Natural Killer Cell Immunotherapy for Enhanced Antibody Directed Cellular Cytotoxicity Blood. 128: 3363-3363. DOI: 10.1182/Blood.V128.22.3363.3363  0.242
2016 Rosen J, Rezner B, Robbins D, Hardy I, Peralta E, Maine C, Sabouri M, Reynal S, Truong C, Moreno S, Foster H, Borchelt S, Meza M, Thompson L, Fontenot J, et al. Identification of Small Molecule Modulators to Enhance the Therapeutic Properties of Chimeric Antigen Receptor T Cells Blood. 128: 4712-4712. DOI: 10.1182/BLOOD.V128.22.4712.4712  0.242
2002 Jeffries S, Robbins DJ, Capobianco AJ. Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line. Molecular and Cellular Biology. 22: 3927-41. PMID 11997524 DOI: 10.1128/MCB.22.11.3927-3941.2002  0.241
2016 Abujarour R, Lan W, Lee TT, Bonello G, Meza M, Robinson M, Clarke R, Truong C, Lynn C, Robbins D, Rezner B, Abbot SE, Shoemaker D, Valamehr B. Efficient Site-Specific Multi-Gene Engineering of Renewable Pluripotent Cells for Generation of Off-the-Shelf Hematopoietic Immunotherapeutics Blood. 128: 5887-5887. DOI: 10.1182/Blood.V128.22.5887.5887  0.24
2019 Winterbottom EF, Ban Y, Sun X, Capobianco AJ, Marsit CJ, Chen X, Wang L, Karagas MR, Robbins DJ. Transcriptome-wide analysis of changes in the fetal placenta associated with prenatal arsenic exposure in the New Hampshire Birth Cohort Study. Environmental Health : a Global Access Science Source. 18: 100. PMID 31752878 DOI: 10.1186/S12940-019-0535-X  0.237
2016 Clarke R, Groff B, Sasaki J, Bauer M, Lee TT, Lan W, Burrascano M, Abujarour R, Bonello G, Robinson M, Foster H, Robbins D, Wolchko S, Shoemaker D, Abbot SE, et al. Genetically Enhanced Pluripotent Stem Cell-Derived T Lymphocytes for Off-the-Shelf Cellular Immunotherapy Blood. 128: 2164-2164. DOI: 10.1182/Blood.V128.22.2164.2164  0.237
2013 Fei DL, Koestler DC, Li Z, Giambelli C, Sanchez-Mejias A, Gosse JA, Marsit CJ, Karagas MR, Robbins DJ. Association between In Utero arsenic exposure, placental gene expression, and infant birth weight: a US birth cohort study. Environmental Health : a Global Access Science Source. 12: 58. PMID 23866971 DOI: 10.1186/1476-069X-12-58  0.233
2016 Green BB, Karagas MR, Punshon T, Jackson BP, Robbins DJ, Houseman EA, Marsit CJ. Epigenome-Wide Assessment of DNA Methylation in the Placenta and Arsenic Exposure in the New Hampshire Birth Cohort Study (USA). Environmental Health Perspectives. PMID 26771251 DOI: 10.1289/Ehp.1510437  0.233
2004 Stegman MA, Goetz JA, Ascano M, Ogden SK, Nybakken KE, Robbins DJ. The Kinesin-related protein Costal2 associates with membranes in a Hedgehog-sensitive, Smoothened-independent manner. The Journal of Biological Chemistry. 279: 7064-71. PMID 14645371 DOI: 10.1074/Jbc.M311794200  0.23
2001 Zeng X, Goetz JA, Suber LM, Scott WJ, Schreiner CM, Robbins DJ. A freely diffusible form of Sonic hedgehog mediates long-range signalling. Nature. 411: 716-20. PMID 11395778 DOI: 10.1038/35079648  0.227
2018 Rodriguez Blanco J, Li B, Long J, Orthon D, Ayad N, MaCrea H, Roussel M, Weiss W, Capobianco A, Robbins D. DDIS-11. A CK1a ACTIVATOR PENETRATES THE BRAIN, AND SHOWS EFFICACY AGAINST DRUG-RESISTANT METASTATIC MEDULLOBLASTOMA Neuro-Oncology. 20: vi71-vi71. DOI: 10.1093/Neuonc/Noy148.290  0.227
2010 Giambelli C, Fei DL, Wang H, Robbins DJ. Repurposing an old anti-fungal drug as a Hedgehog inhibitor. Protein & Cell. 1: 417-8. PMID 21203953 DOI: 10.1007/S13238-010-0063-5  0.227
2014 Abujarour R, Bennett M, Valamehr B, Lee TT, Robinson M, Robbins D, Le T, Lai K, Flynn P. Myogenic differentiation of muscular dystrophy-specific induced pluripotent stem cells for use in drug discovery. Stem Cells Translational Medicine. 3: 149-60. PMID 24396035 DOI: 10.5966/Sctm.2013-0095  0.226
2019 Richardson A, Collins S, Inagaki A, Armstrong V, Roussel M, Robbins D, Ayad N, Jolly D, Kasahara N. THER-30. COMBINATION TOCA 511 & 5-FC SIGNIFICANTLY EXTENDS SURVIVAL IN A MURINE ORTHOTOPIC MODEL OF INTRACEREBELLAR MEDULLOBLASTOMA Neuro-Oncology. 21: ii120-ii120. DOI: 10.1093/Neuonc/Noz036.235  0.223
1981 Robbins D, Odom OW, Lynch J, Kramer G, Hardesty B, Liou R, Ofengand J. Position of transfer ribonucleic acid on Escherichia coli ribosomes. Distance from the 3′ end of 16S ribonucleic acid to three points on phenylalanine-accepting transfer ribonucleic acid in the donor site of 70S ribosomes Biochemistry. 20: 5301-5309. PMID 6170320 DOI: 10.1021/Bi00521A033  0.215
2017 Pei X, Chan H, Liu S, Scott A, Pimentel E, Slingerland J, Robbins D, Capobianco A, Bai F. Abstract P6-08-08: GATA3 inhibits breast basal-like tumorigenesis Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P6-08-08  0.215
2006 Goetz JA, Singh S, Suber LM, Kull FJ, Robbins DJ. A highly conserved amino-terminal region of sonic hedgehog is required for the formation of its freely diffusible multimeric form. The Journal of Biological Chemistry. 281: 4087-93. PMID 16339763 DOI: 10.1074/Jbc.M511427200  0.215
2014 Cutler CS, Shoemaker D, Westervelt P, Couriel DR, Vasu S, Isola LM, Karanes C, Newell L, Rezner B, Guerrettaz L, Robbins D, Medcalf A, Wolchko S, Ferraro J, Multani PS. Ex Vivo Pharmacologic Modulation in a Nutrient-Rich Medium to Accelerate Engraftment of Human Umbilical Cord Blood Blood. 124: 3807-3807. DOI: 10.1182/blood.V124.21.3807.3807  0.213
2017 Richardson AM, Collins SA, Inagaki A, Armstrong VL, Roussel M, Jolly D, Robbins DJ, Ayad N, Kasahara N. Pdtm-19. Toca 511 & Toca Fc: Pre-Clinical Proof Of Concept In Medulloblastoma Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.783  0.21
2005 Scott WJ, Schreiner CM, Goetz JA, Robbins D, Bell SM. Cadmium-induced postaxial forelimb ectrodactyly: association with altered sonic hedgehog signaling. Reproductive Toxicology (Elmsford, N.Y.). 19: 479-85. PMID 15749261 DOI: 10.1016/j.reprotox.2004.11.013  0.21
1983 Robbins D, Hardesty B. Comparison of ribosomal entry and acceptor transfer ribonucleic acid binding sites on Escherichia coli 70S ribosomes. Fluorescence energy transfer measurements from Phe-tRNAPhe to the 3' end of 16S ribonucleic acid. Biochemistry. 22: 5675-9. PMID 6197085 DOI: 10.1021/Bi00293A034  0.207
1991 Boulton TG, Nye SH, Robbins DJ, Ip NY, Radziejewska E, Morgenbesser SD, DePinho RA, Panayotatos N, Cobb MH, Yancopoulos GD. ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell. 65: 663-75. PMID 2032290 DOI: 10.1016/0092-8674(91)90098-J  0.205
2000 Stegman MA, Vallance JE, Elangovan G, Sosinski J, Cheng Y, Robbins DJ. Identification of a tetrameric hedgehog signaling complex. The Journal of Biological Chemistry. 275: 21809-12. PMID 10825151 DOI: 10.1074/jbc.C000043200  0.204
2002 Nybakken KE, Turck CW, Robbins DJ, Bishop JM. Hedgehog-stimulated phosphorylation of the kinesin-related protein Costal2 is mediated by the serine/threonine kinase fused. The Journal of Biological Chemistry. 277: 24638-47. PMID 11934882 DOI: 10.1074/jbc.M110730200  0.201
1980 Odom OW, Robbins DJ, Lynch J, Dottavio-Martin D, Kramer G, Hardesty B. Distances between 3′ ends of ribosomal ribonucleic acids reassembled into Escherichia coli ribosomes Biochemistry. 19: 5947-5954. PMID 6162473 DOI: 10.1021/Bi00567A001  0.196
2007 Stegman M, Robbins D. Biochemical fractionation of Drosophila cells. Methods in Molecular Biology (Clifton, N.J.). 397: 203-13. PMID 18025722 DOI: 10.1007/978-1-59745-516-9_14  0.194
1997 Lin-Goerke JL, Robbins DJ, Burczak JD. PCR-Based Random Mutagenesis Using Manganese and Reduced dNTP Concentration Biotechniques. 23: 409-412. PMID 9298207 DOI: 10.2144/97233Bm12  0.193
2022 Ben Nasr M, Robbins D, Parone P, Usuelli V, Tacke R, Seelam AJ, Driver E, Le T, Sabouri-Ghomi M, Guerrettaz L, Shoemaker D, Fiorina P. Pharmacologically Enhanced Regulatory Hematopoietic Stem Cells Revert Experimental Autoimmune Diabetes and Mitigate Other Autoimmune Disorders. Journal of Immunology (Baltimore, Md. : 1950). 208: 1554-1565. PMID 35321879 DOI: 10.4049/jimmunol.2100949  0.186
2012 Valamehr B, Abujarour R, Robinson M, Le T, Robbins D, Shoemaker D, Flynn P. A novel platform to enable the high-throughput derivation and characterization of feeder-free human iPSCs. Scientific Reports. 2: 213. PMID 22355727 DOI: 10.1038/Srep00213  0.175
2014 Valamehr B, Robinson M, Abujarour R, Rezner B, Vranceanu F, Le T, Medcalf A, Lee TT, Fitch M, Robbins D, Flynn P. Platform for induction and maintenance of transgene-free hiPSCs resembling ground state pluripotent stem cells. Stem Cell Reports. 2: 366-81. PMID 24672758 DOI: 10.1016/J.Stemcr.2014.01.014  0.172
2009 Donald RG, Skwish S, Forsyth RA, Anderson JW, Zhong T, Burns C, Lee S, Meng X, LoCastro L, Jarantow LW, Martin J, Lee SH, Taylor I, Robbins D, Malone C, et al. A Staphylococcus aureus fitness test platform for mechanism-based profiling of antibacterial compounds. Chemistry & Biology. 16: 826-36. PMID 19716473 DOI: 10.1016/j.chembiol.2009.07.004  0.163
2021 Movassagh H, Halchenko Y, Sampath V, Nygaard UC, Jackson B, Robbins D, Li Z, Nadeau KC, Karagas MR. Maternal gestational mercury exposure in relation to cord blood T cell alterations and placental gene expression signatures. Environmental Research. 111385. PMID 34129869 DOI: 10.1016/j.envres.2021.111385  0.159
2010 Xu HH, Trawick JD, Haselbeck RJ, Forsyth RA, Yamamoto RT, Archer R, Patterson J, Allen M, Froelich JM, Taylor I, Nakaji D, Maile R, Kedar GC, Pilcher M, Brown-Driver V, ... ... Robbins D, et al. Staphylococcus aureus TargetArray: comprehensive differential essential gene expression as a mechanistic tool to profile antibacterials. Antimicrobial Agents and Chemotherapy. 54: 3659-70. PMID 20547796 DOI: 10.1128/AAC.00308-10  0.15
2002 Forsyth RA, Haselbeck RJ, Ohlsen KL, Yamamoto RT, Xu H, Trawick JD, Wall D, Wang L, Brown-Driver V, Froelich JM, Kedar GC, King P, McCarthy M, Malone C, Misiner B, ... Robbins D, et al. A genome-wide strategy for the identification of essential genes in Staphylococcus aureus Molecular Microbiology. 43: 1387-1400. PMID 11952893 DOI: 10.1046/J.1365-2958.2002.02832.X  0.147
2014 Aboulaich N, Chung WK, Thompson JH, Larkin C, Robbins D, Zhu M. A novel approach to monitor clearance of host cell proteins associated with monoclonal antibodies. Biotechnology Progress. 30: 1114-24. PMID 25044920 DOI: 10.1002/btpr.1948  0.144
2013 Cutler C, Multani P, Robbins D, Kim HT, Le T, Hoggatt J, Pelus LM, Desponts C, Chen YB, Rezner B, Armand P, Koreth J, Glotzbecker B, Ho VT, Alyea E, et al. Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. Blood. 122: 3074-81. PMID 23996087 DOI: 10.1182/Blood-2013-05-503177  0.126
2022 Bosley A, Cook K, Lin S, Robbins D. Improved process intermediate stability through the identification and elimination of reactive glycation residues - a monoclonal antibody case study. Bioengineered. 13: 14402-14412. PMID 35757891 DOI: 10.1080/21655979.2022.2086350  0.123
2020 Luo H, Li Y, Robbins D, Wang SC, Xi G, Cox M, Nicholson SM, Wei C, Pabst TM, Wang WK. Safety Risk Management for Low Molecular Weight Process-related Impurities in Monoclonal Antibody Therapeutics: Categorization, Risk Assessment, Testing Strategy, and Process Development With Leveraging Clearance Potential. Biotechnology Progress. e3119. PMID 33373106 DOI: 10.1002/btpr.3119  0.118
2019 Prentice J, Vu D, Robbins D, Ferreira G. Process Characterization Strategy for a Precipitation Step for Host Cell Protein Reduction. Biotechnology Progress. e2908. PMID 31513727 DOI: 10.1002/btpr.2908  0.111
2019 Ranjan S, Chung WK, Zhu M, Robbins D, Cramer SM. Implementation of an Experimental and Computational Tool Set to Study Protein-mAb Interactions. Biotechnology Progress. e2825. PMID 31017347 DOI: 10.1002/btpr.2825  0.103
2017 Chung WK, Russell B, Yang Y, Handlogten M, Hudak S, Cao M, Wang J, Robbins D, Ahuja S, Zhu M. Effects of antibody disulfide bond reduction on purification process performance and final drug substance stability. Biotechnology and Bioengineering. PMID 28186329 DOI: 10.1002/Bit.26265  0.098
2019 Ranjan S, Chung WK, Hofele R, Thompson JH, Bee J, Zhang L, Robbins D, Cramer SM. Investigation of cathepsin D-mAb interactions using a combined experimental and computational tool set. Biotechnology and Bioengineering. PMID 30882893 DOI: 10.1002/Bit.26968  0.094
2019 Chestnut C, Smelser W, Dum T, Bechtel M, Hand L, Michel C, Bawajeeh A, Zohreh S, Liu W, Anant S, Robbins D, Holzbeierlein JM, Hamilton-Reeves J, Lee EK. Glycemic impact of a diet and lifestyle intervention on diabetics and prediabetics during treatment for non-muscle invasive bladder cancer. Nutrition and Cancer. 1-6. PMID 31588804 DOI: 10.1080/01635581.2019.1672761  0.086
2020 Lease N, Kay LM, Brown GW, Chavez DE, Robbins D, Byrd EFC, Imler GH, Parrish DA, Manner VW. Synthesis of Erythritol Tetranitrate (ETN) Derivatives: Functional Group Tuning of Explosive Sensitivity. The Journal of Organic Chemistry. PMID 32102544 DOI: 10.1021/Acs.Joc.9B03344  0.076
2015 Aguirre LE, Colleluori G, Fowler KE, Jan IZ, Villareal K, Qualls C, Robbins D, Villareal DT, Armamento-Villareal R. High aromatase activity in hypogonadal men is associated with higher spine bone mineral density, increased truncal fat and reduced lean mass. European Journal of Endocrinology / European Federation of Endocrine Societies. 173: 167-74. PMID 26142101 DOI: 10.1530/EJE-14-1103  0.067
2017 Keller WR, Evans ST, Ferreira G, Robbins D, Cramer SM. Understanding operational system differences for transfer of miniaturized chromatography column data using simulations. Journal of Chromatography. A. PMID 28811099 DOI: 10.1016/j.chroma.2017.07.091  0.058
2014 Sahasrabuddhe VV, Gravitt PE, Dunn ST, Robbins D, Brown D, Allen RA, Eby YJ, Smith KM, Zuna RE, Zhang RR, Gold MA, Schiffman M, Walker JL, Castle PE, Wentzensen N. Evaluation of clinical performance of a novel urine-based HPV detection assay among women attending a colposcopy clinic. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 60: 414-7. PMID 24881489 DOI: 10.1016/J.Jcv.2014.04.016  0.057
2005 Best LG, Zhang Y, Lee ET, Yeh JL, Cowan L, Palmieri V, Roman M, Devereux RB, Fabsitz RR, Tracy RP, Robbins D, Davidson M, Ahmed A, Howard BV. C-reactive protein as a predictor of cardiovascular risk in a population with a high prevalence of diabetes: the Strong Heart Study. Circulation. 112: 1289-95. PMID 16116058 DOI: 10.1161/Circulationaha.104.489260  0.057
2019 Song X, Waitman LR, Hu Y, Yu ASL, Robbins D, Liu M. An exploration of ontology-based EMR data abstraction for diabetic kidney disease prediction. Amia Joint Summits On Translational Science Proceedings. Amia Joint Summits On Translational Science. 2019: 704-713. PMID 31259027  0.053
2006 Ebbesson SO, Laston S, Wenger CR, Dyke B, Romenesko T, Swenson M, Fabsitz RR, MacCluer JW, Devereux R, Roman M, Robbins D, Howard BV. Recruitment and community interactions in the GOCADAN study. International Journal of Circumpolar Health. 65: 55-64. PMID 16544648 DOI: 10.3402/Ijch.V65I1.17882  0.05
2015 Keller WR, Evans ST, Ferreira G, Robbins D, Cramer SM. Use of MiniColumns for linear isotherm parameter estimation and prediction of benchtop column performance. Journal of Chromatography. A. 1418: 94-102. PMID 26422303 DOI: 10.1016/j.chroma.2015.09.038  0.045
2020 Prentice J, Evans ST, Robbins D, Ferreira G. Pressure-Flow experiments, packing, and modeling for scale-up of a mixed mode chromatography column for biopharmaceutical manufacturing. Journal of Chromatography. A. 1625: 461117. PMID 32709364 DOI: 10.1016/j.chroma.2020.461117  0.044
1998 Kim KS, Robbins D, Turner M, Adams-Campbell LL. Anthropometric determinants of risk factors in an African American population. American Journal of Human Biology : the Official Journal of the Human Biology Council. 10: 249-258. PMID 28561442 DOI: 10.1002/(SICI)1520-6300(1998)10:2<249::AID-AJHB10>3.0.CO;2-8  0.043
2005 Nobmann ED, Ponce R, Mattil C, Devereux R, Dyke B, Ebbesson SO, Laston S, MacCluer J, Robbins D, Romenesko T, Ruotolo G, Wenger CR, Howard BV. Dietary intakes vary with age among Eskimo adults of Northwest Alaska in the GOCADAN study, 2000-2003. The Journal of Nutrition. 135: 856-62. PMID 15795447 DOI: 10.1093/Jn/135.4.856  0.043
2021 Krause DS, Davis K, Dowd D, Robbins DJ. A Novel Real-Time PCR Assay for Detection of HLA-A*31:01 in Individuals Being Considered for Carbamazepine Therapy. Cns Spectrums. 26: 154-155. PMID 34127142 DOI: 10.1017/S1092852920002461  0.042
2022 Keller WR, Evans ST, Ferreira G, Robbins D, Cramer SM. Understanding the effects of system differences for parameter estimation and scale-up of high throughput chromatographic data. Journal of Chromatography. A. 1661: 462696. PMID 34875516 DOI: 10.1016/j.chroma.2021.462696  0.04
2011 Tao Y, Carta G, Ferreira G, Robbins D. Adsorption of deamidated antibody variants on macroporous and dextran-grafted cation exchangers: I. Adsorption equilibrium. Journal of Chromatography. A. 1218: 1519-29. PMID 21306721 DOI: 10.1016/J.Chroma.2011.01.049  0.039
2022 Thelen M, Sutlive T, Traygord B, Robbins D, Schiferl R, Brock B, Demsher K, Godin A, Anstead K. Demonstration and Evaluation of Physical Examination Techniques Intended to Identify Proximal Femoral Bone Stress Injuries. Medical Journal (Fort Sam Houston, Tex.). 66-73. PMID 34940971  0.035
2018 Lease N, Kay L, Chavez DE, Robbins D, Manner VW. Increased handling sensitivity of molten erythritol tetranitrate (ETN). Journal of Hazardous Materials. 367: 546-549. PMID 30641424 DOI: 10.1016/J.Jhazmat.2018.12.110  0.035
2017 Aguirre LE, Colleluori G, Dorin R, Robbins D, Chen R, Jiang B, Qualls C, Villareal DT, Armamento-Villareal R. Hypogonadal Men with Higher Body Mass Index have Higher Bone Density and Better Bone Quality but Reduced Muscle Density. Calcified Tissue International. PMID 28856390 DOI: 10.1007/s00223-017-0316-x  0.029
2011 Tao Y, Almodovar EX, Carta G, Ferreira G, Robbins D. Adsorption kinetics of deamidated antibody variants on macroporous and dextran-grafted cation exchangers. III. Microscopic studies. Journal of Chromatography. A. 1218: 8027-35. PMID 21955780 DOI: 10.1016/J.Chroma.2011.09.010  0.029
2020 Jacobson LT, Collins TC, Lucas M, Zackula R, Okut H, Nazir N, Robbins D, Stern JE, Wolfe M, Grainger DA. Electronic Monitoring Of Mom's Schedule (eMOMS™): Protocol for a feasibility randomized controlled trial to improve postpartum weight, blood sugars, and breastfeeding among high BMI women. Contemporary Clinical Trials Communications. 18: 100565. PMID 32346648 DOI: 10.1016/j.conctc.2020.100565  0.029
2019 Aguirre LE, Colleluori G, Robbins D, Dorin R, Shah VO, Chen R, Jan IZ, Qualls C, Villareal DT, Armamento-Villareal R. Bone and body composition response to testosterone therapy vary according to polymorphisms in the CYP19A1 gene. Endocrine. PMID 31325085 DOI: 10.1007/s12020-019-02008-6  0.028
2010 Hecht EM, Bennett GL, Brown KW, Robbins D, Hyams ES, Taneja SS, Stifelman MA. Laparoscopic and open partial nephrectomy: frequency and long-term follow-up of postoperative collections. Radiology. 255: 476-84. PMID 20413760 DOI: 10.1148/radiol.10091256  0.025
2011 Tao Y, Carta G, Ferreira G, Robbins D. Adsorption of deamidated antibody variants on macroporous and dextran-grafted cation exchangers: II. Adsorption kinetics. Journal of Chromatography. A. 1218: 1530-7. PMID 21300361 DOI: 10.1016/j.chroma.2011.01.050  0.02
2009 Shekhtman EM, Anne K, Melkonyan HS, Robbins DJ, Warsof SL, Umansky SR. Optimization of transrenal DNA analysis: detection of fetal DNA in maternal urine. Clinical Chemistry. 55: 723-9. PMID 19181739 DOI: 10.1373/clinchem.2008.113050  0.02
2017 Nagula S, Pourmand K, Aslanian H, Bucobo JC, Gonda T, Gonzalez S, Goodman A, Gross SA, Ho S, DiMaio CJ, Kim M, Pais S, Poneros J, Robbins D, Schnoll-Sussman F, et al. Comparing EUS-Fine Needle Aspiration and EUS-Fine Needle Biopsy for Solid Lesions: A Multicenter, Randomized Trial. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 28624647 DOI: 10.1016/J.Cgh.2017.06.013  0.02
2019 Pittas AG, Dawson-Hughes B, Sheehan P, Ware JH, Knowler WC, Aroda VR, Brodsky I, Ceglia L, Chadha C, Chatterjee R, Desouza C, Dolor R, Foreyt J, Fuss P, Ghazi A, ... ... Robbins D, et al. Vitamin D Supplementation and Prevention of Type 2 Diabetes. The New England Journal of Medicine. PMID 31173679 DOI: 10.1056/Nejmoa1900906  0.019
2006 Borm PJ, Robbins D, Haubold S, Kuhlbusch T, Fissan H, Donaldson K, Schins R, Stone V, Kreyling W, Lademann J, Krutmann J, Warheit D, Oberdorster E. The potential risks of nanomaterials: a review carried out for ECETOC. Particle and Fibre Toxicology. 3: 11. PMID 16907977 DOI: 10.1186/1743-8977-3-11  0.018
2017 Cuzick JM, Cadman L, Ahmad AS, Ho L, Terry G, Kleeman M, Lyons D, Austin J, Stoler MH, Vibat CR, Dockter J, Robbins D, Billings PR, Erlander MG. Performance and Diagnostic Accuracy of a Urine-Based Human Papillomavirus Assay in a Referral Population. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 28223432 DOI: 10.1158/1055-9965.EPI-16-0960  0.016
2007 Lepor H, Robbins D. Inguinal hernias in men undergoing open radical retropubic prostatectomy. Urology. 70: 961-4. PMID 18068454 DOI: 10.1016/j.urology.2007.08.038  0.016
2020 Hennessy B, Vicari J, Bernstein B, Chapman F, Khaykis I, Littenberg G, Robbins D. GUIDANCE FOR RESUMING GI ENDOSCOPY AND PRACTICE OPERATIONS AFTER THE COVID-19 PANDEMIC. Gastrointestinal Endoscopy. PMID 32437712 DOI: 10.1016/j.gie.2020.05.006  0.014
2017 Colleluori G, Aguirre L, Dorin R, Robbins D, Blevins D, Barnouin Y, Chen R, Qualls C, Villareal DT, Armamento-Villareal R. Hypogonadal men with type 2 diabetes mellitus have smaller bone size and lower bone turnover. Bone. PMID 28323146 DOI: 10.1016/j.bone.2017.03.039  0.012
2012 Kothari T, Jormark S, Machnicki S, Robbins D. Acute purulent erosive appendicitis diagnosed during colonoscopy. Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society. 24: 292. PMID 22725128 DOI: 10.1111/j.1443-1661.2011.01226.x  0.01
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