Laura Attardi - Publications

Affiliations: 
Stanford University, Palo Alto, CA 

104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mangoli A, Wu S, Liu HQ, Aksu M, Jain V, Foreman BE, Regal JA, Weidenhammer LB, Stewart CE, Guerra Garcia ME, Hocke E, Abramson K, Williams NT, Luo L, Deland K, ... Attardi L, et al. ( ) disruption sensitizes spatially-directed H3.3K27M/TP53 diffuse midline gliomas to radiation therapy. Biorxiv : the Preprint Server For Biology. PMID 37904990 DOI: 10.1101/2023.10.18.562892  0.333
2023 Kaiser AM, Gatto A, Hanson KJ, Zhao RL, Raj N, Ozawa MG, Seoane JA, Bieging-Rolett KT, Wang M, Li I, Trope WL, Liou DZ, Shrager JB, Plevritis SK, Newman AM, ... ... Attardi LD, et al. p53 governs an AT1 differentiation programme in lung cancer suppression. Nature. PMID 37468633 DOI: 10.1038/s41586-023-06253-8  0.439
2023 Morral C, Ayyaz A, Kuo HC, Fink M, Verginadis I, Daniel AR, Burner DN, Driver LM, Satow S, Hasapis S, Ghinnagow R, Luo L, Ma Y, Attardi LD, Koumenis C, et al. p53 promotes revival stem cells in the regenerating intestine after severe radiation injury. Biorxiv : the Preprint Server For Biology. PMID 37162959 DOI: 10.1101/2023.04.27.538576  0.362
2023 Mello SS, Flowers BM, Mazur PK, Lee JJ, Müller F, Denny SK, Ferreira S, Hanson K, Kim SK, Greenleaf WJ, Wood LD, Attardi LD. Multifaceted role for p53 in pancreatic cancer suppression. Proceedings of the National Academy of Sciences of the United States of America. 120: e2211937120. PMID 36848578 DOI: 10.1073/pnas.2211937120  0.483
2022 Raj N, Wang M, Seoane JA, Zhao RL, Kaiser AM, Moonie NA, Demeter J, Boutelle AM, Kerr CH, Mulligan AS, Moffatt C, Zeng SX, Lu H, Barna M, Curtis C, ... ... Attardi LD, et al. The Mettl3 epitranscriptomic writer amplifies p53 stress responses. Molecular Cell. PMID 35512709 DOI: 10.1016/j.molcel.2022.04.010  0.464
2022 Kuo HC, Luo L, Ma Y, Williams NT, da Silva Campos L, Attardi LD, Lee CL, Kirsch DG. The p53 Transactivation Domain 1-Dependent Response to Acute DNA Damage in Endothelial Cells Protects against Radiation-Induced Cardiac Injury. Radiation Research. PMID 35512345 DOI: 10.1667/RADE-22-00001.1  0.411
2021 Wang M, Attardi LD. A Balancing Act: p53 Activity from Tumor Suppression to Pathology and Therapeutic Implications. Annual Review of Pathology. PMID 34699262 DOI: 10.1146/annurev-pathol-042320-025840  0.429
2021 Tiu GC, Kerr CH, Forester CM, Krishnarao PS, Rosenblatt HD, Raj N, Lantz TC, Zhulyn O, Bowen ME, Shokat L, Attardi LD, Ruggero D, Barna M. A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies. Developmental Cell. PMID 34242585 DOI: 10.1016/j.devcel.2021.06.013  0.345
2021 Bieging-Rolett KT, Attardi LD. Zmat3 splices together p53-dependent tumor suppression. Molecular & Cellular Oncology. 8: 1898523. PMID 34027039 DOI: 10.1080/23723556.2021.1898523  0.36
2021 Bowen ME, Mulligan AS, Sorayya A, Attardi LD. Puma- and Caspase9-mediated apoptosis is dispensable for p53-driven neural crest-based developmental defects. Cell Death and Differentiation. PMID 33574585 DOI: 10.1038/s41418-021-00738-7  0.489
2021 Valente LJ, Attardi LD. P53 orchestrates a complex symphony of cellular processes during oncosuppression. Molecular & Cellular Oncology. 8: 1852066. PMID 33553606 DOI: 10.1080/23723556.2020.1852066  0.407
2021 Boutelle AM, Attardi LD. p53 and Tumor Suppression: It Takes a Network. Trends in Cell Biology. PMID 33518400 DOI: 10.1016/j.tcb.2020.12.011  0.446
2021 Maor-Nof M, Shipony Z, Lopez-Gonzalez R, Nakayama L, Zhang YJ, Couthouis J, Blum JA, Castruita PA, Linares GR, Ruan K, Ramaswami G, Simon DJ, Nof A, Santana M, Han K, ... ... Attardi LD, et al. p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR). Cell. PMID 33482083 DOI: 10.1016/j.cell.2020.12.025  0.31
2020 Bieging-Rolett KT, Kaiser AM, Morgens DW, Boutelle AM, Seoane JA, Van Nostrand EL, Zhu C, Houlihan SL, Mello SS, Yee BA, McClendon J, Pierce SE, Winters IP, Wang M, Connolly AJ, ... ... Attardi LD, et al. Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program. Molecular Cell. 80: 452-469.e9. PMID 33157015 DOI: 10.1016/j.molcel.2020.10.022  0.585
2020 Valente LJ, Tarangelo A, Li AM, Naciri M, Raj N, Boutelle AM, Li Y, Mello SS, Bieging-Rolett K, DeBerardinis RJ, Ye J, Dixon SJ, Attardi LD. p53 deficiency triggers dysregulation of diverse cellular processes in physiological oxygen. The Journal of Cell Biology. 219. PMID 32886745 DOI: 10.1083/Jcb.201908212  0.472
2020 Flowers B, Xu H, Hanson K, Curtis C, Vogel H, Wood L, Attardi LD. Abstract IA14: Deconstructing the origins of PDAC development Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-Ia14  0.395
2019 Bowen ME, McClendon J, Long HK, Sorayya A, Van Nostrand JL, Wysocka J, Attardi LD. The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes. Developmental Cell. PMID 31178404 DOI: 10.1016/J.Devcel.2019.05.015  0.43
2019 Jacobs SBR, Van Nostrand JL, Bowen ME, Baker JC, Attardi LD. Siva plays a critical role in mouse embryonic development. Cell Death and Differentiation. PMID 31164717 DOI: 10.1038/S41418-019-0358-X  0.405
2019 Bowen ME, Attardi LD. The role of p53 in developmental syndromes. Journal of Molecular Cell Biology. PMID 30624728 DOI: 10.1093/Jmcb/Mjy087  0.424
2019 Flowers B, Xu H, Hanson K, Curtis C, Vogel H, Wood LD, Attardi LD. Abstract I15: Deciphering the origins of PDAC development Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-I15  0.36
2019 Flowers BM, Xu H, Hanson K, Curtis C, Vogel H, Wood LD, Attardi LD. Abstract A15: Elucidating the role of p53 in the cellular origins of pancreatic cancer development Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-A15  0.473
2018 Kaiser AM, Attardi LD. Deconstructing networks of p53-mediated tumor suppression in vivo. Cell Death and Differentiation. 25: 93-103. PMID 31745313 DOI: 10.1038/cdd.2017.171  0.47
2018 Durruthy-Durruthy R, Sperry ED, Bowen ME, Attardi LD, Heller S, Martin DM. Single Cell Transcriptomics Reveal Abnormalities in Neurosensory Patterning of the Mutant Mouse Ear. Frontiers in Genetics. 9: 473. PMID 30459807 DOI: 10.3389/Fgene.2018.00473  0.307
2018 Mello SS, Attardi LD. Neat-en-ing up our understanding of p53 pathways in tumor suppression. Cell Cycle (Georgetown, Tex.). PMID 29895201 DOI: 10.1080/15384101.2018.1464835  0.415
2018 Calo E, Gu B, Bowen ME, Aryan F, Zalc A, Liang J, Flynn RA, Swigut T, Chang HY, Attardi LD, Wysocka J. Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders. Nature. PMID 29364875 DOI: 10.1038/Nature25449  0.347
2018 Tarangelo A, Magtanong L, Bieging-Rolett KT, Li Y, Ye J, Attardi LD, Dixon SJ. p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells. Cell Reports. 22: 569-575. PMID 29346757 DOI: 10.1016/j.celrep.2017.12.077  0.415
2018 Mello SS, Bieging-Rolett K, Kaiser A, Valente EJ, Raj N, McClendon J, Flowers BM, Morgens DW, Bassik MC, Attardi LD. Abstract IA07: Deconstructing p53 pathways in tumor suppression Cancer Research. 78. DOI: 10.1158/1538-7445.Mousemodels17-Ia07  0.515
2017 Mello SS, Attardi LD. Deciphering p53 signaling in tumor suppression. Current Opinion in Cell Biology. 51: 65-72. PMID 29195118 DOI: 10.1016/j.ceb.2017.11.005  0.483
2017 Kaiser AM, Attardi LD. Deconstructing networks of p53-mediated tumor suppression in vivo. Cell Death and Differentiation. PMID 29099489 DOI: 10.1038/cdd.2017.171  0.479
2017 Mello SS, Valente LJ, Raj N, Seoane JA, Flowers BM, McClendon J, Bieging-Rolett KT, Lee J, Ivanochko D, Kozak MM, Chang DT, Longacre TA, Koong AC, Arrowsmith CH, Kim SK, ... ... Attardi LD, et al. A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer. Cancer Cell. 32: 460-473.e6. PMID 29017057 DOI: 10.1016/J.Ccell.2017.09.007  0.428
2017 Mello SS, Sinow C, Raj N, Mazur PK, Bieging-Rolett K, Broz DK, Imam JFC, Vogel H, Wood LD, Sage J, Hirose T, Nakagawa S, Rinn J, Attardi LD. Neat1 is a p53-inducible lincRNA essential for transformation suppression. Genes & Development. PMID 28698299 DOI: 10.1101/Gad.284661.116  0.695
2017 Filipescu D, Naughtin M, Podsypanina K, Lejour V, Wilson L, Gurard-Levin ZA, Orsi GA, Simeonova I, Toufektchan E, Attardi LD, Toledo F, Almouzni G. Essential role for centromeric factors following p53 loss and oncogenic transformation. Genes & Development. PMID 28356341 DOI: 10.1101/Gad.290924.116  0.513
2017 Van Nostrand JL, Bowen ME, Vogel H, Barna M, Attardi LD. The p53 family members have distinct roles during mammalian embryonic development. Cell Death and Differentiation. PMID 28211873 DOI: 10.1038/Cdd.2016.128  0.429
2017 Simmons A, Kong C, Eyben Rv, Attardi L, Ma X, Le Q, Nathan C. Abstract 62: Loss of PERP p53/p63 target gene may indicate tumorigenesis at the margin and local recurrence Clinical Cancer Research. 23: 62-62. DOI: 10.1158/1557-3265.Aacrahns17-62  0.408
2016 Raj N, Attardi LD. The Transactivation Domains of the p53 Protein. Cold Spring Harbor Perspectives in Medicine. PMID 27864306 DOI: 10.1101/Cshperspect.A026047  0.406
2016 Schmitt AM, Garcia JT, Hung T, Flynn RA, Shen Y, Qu K, Payumo AY, Peres-da-Silva A, Broz DK, Baum R, Guo S, Chen JK, Attardi LD, Chang HY. An inducible long noncoding RNA amplifies DNA damage signaling. Nature Genetics. PMID 27668660 DOI: 10.1038/Ng.3673  0.362
2016 Jackson PK, Attardi LD. p73 and FoxJ1: Programming Multiciliated Epithelia. Trends in Cell Biology. PMID 26988441 DOI: 10.1016/J.Tcb.2016.03.001  0.468
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Attardi LD, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886  0.542
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Attardi LD, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.584
2016 Bieging-Rolett KT, Johnson TM, Brady CA, Beaudry VG, Pathak N, Han S, Attardi LD. p19(Arf) is required for the cellular response to chronic DNA damage. Oncogene. PMID 26725325 DOI: 10.1038/onc.2015.490  0.367
2015 Mazur PK, Herner A, Mello SS, Wirth M, Hausmann S, Sánchez-Rivera FJ, Lofgren SM, Kuschma T, Hahn SA, Vangala D, Trajkovic-Arsic M, Gupta A, Heid I, Noël PB, Braren R, ... ... Attardi LD, et al. Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma. Nature Medicine. PMID 26390243 DOI: 10.1038/Nm.3952  0.748
2015 Younger ST, Kenzelmann-Broz D, Jung H, Attardi LD, Rinn JL. Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage. Nucleic Acids Research. 43: 4447-62. PMID 25883152 DOI: 10.1093/nar/gkv284  0.428
2015 Van Nostrand JL, Brisac A, Mello SS, Jacobs SB, Luong R, Attardi LD. The p53 Target Gene SIVA Enables Non-Small Cell Lung Cancer Development. Cancer Discovery. 5: 622-35. PMID 25813352 DOI: 10.1158/2159-8290.CD-14-0921  0.458
2015 Bieging KT, Attardi LD. A piece of the p53 puzzle Nature. 520: 37-38. PMID 25799989 DOI: 10.1038/Nature14374  0.418
2015 Jiang D, LaGory EL, Kenzelmann Brož D, Bieging KT, Brady CA, Link N, Abrams JM, Giaccia AJ, Attardi LD. Analysis of p53 transactivation domain mutants reveals Acad11 as a metabolic target important for p53 pro-survival function. Cell Reports. 10: 1096-109. PMID 25704813 DOI: 10.1016/J.Celrep.2015.01.043  0.45
2014 Van Nostrand JL, Attardi LD. Guilty as CHARGED: p53's expanding role in disease. Cell Cycle (Georgetown, Tex.). 13: 3798-807. PMID 25483057 DOI: 10.4161/15384101.2014.987627  0.403
2014 Van Nostrand JL, Brady CA, Jung H, Fuentes DR, Kozak MM, Johnson TM, Lin CY, Lin CJ, Swiderski DL, Vogel H, Bernstein JA, Attié-Bitach T, Chang CP, Wysocka J, Martin DM, ... Attardi LD, et al. Inappropriate p53 activation during development induces features of CHARGE syndrome. Nature. 514: 228-32. PMID 25119037 DOI: 10.1038/Nature13585  0.42
2014 Bieging KT, Mello SS, Attardi LD. Unravelling mechanisms of p53-mediated tumour suppression Nature Reviews Cancer. 14: 359-370. PMID 24739573 DOI: 10.1038/Nrc3711  0.417
2014 Garcia PB, Attardi LD. Illuminating p53 function in cancer with genetically engineered mouse models. Seminars in Cell & Developmental Biology. 27: 74-85. PMID 24394915 DOI: 10.1016/j.semcdb.2013.12.014  0.477
2013 Raj N, Attardi LD. Tumor suppression: P53 alters immune surveillance to restrain liver cancer Current Biology. 23: R527-R530. PMID 23787049 DOI: 10.1016/J.Cub.2013.04.076  0.392
2013 Mello SS, Attardi LD. Not all p53 gain-of-function mutants are created equal Cell Death and Differentiation. 20: 855-857. PMID 23749181 DOI: 10.1038/cdd.2013.53  0.33
2013 Kenzelmann Broz D, Mello SS, Bieging KT, Jiang D, Dusek RL, Brady CA, Sidow A, Attardi LD. Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses Genes and Development. 27: 1016-1031. PMID 23651856 DOI: 10.1101/Gad.212282.112  0.499
2013 Attardi LD, Sage J. RB goes mitochondrial Genes and Development. 27: 975-979. PMID 23651852 DOI: 10.1101/Gad.219451.113  0.597
2013 Jiang D, Attardi LD. Engaging the p53 metabolic brake drives senescence Cell Research. 23: 739-740. PMID 23478296 DOI: 10.1038/cr.2013.34  0.378
2013 Kong CS, Cao H, Kwok S, Nguyen CM, Jordan RC, Beaudry VG, Attardi LD, Le QT. Loss of the p53/p63 target PERP is an early event in oral carcinogenesis and correlates with higher rate of local relapse. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 115: 95-103. PMID 23217540 DOI: 10.1016/j.oooo.2012.10.017  0.494
2013 Brady CA, Broz DK, Jiang D, Mello SS, Bieging K, Johnson TM, Jarvis LA, Kozak MM, Basak S, Attardi LD. Abstract IA4: Deconstructing p53 pathways in vivo Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-Ia4  0.507
2012 Baron S, Hoang A, Vogel H, Attardi LD. Unimpaired skin carcinogenesis in Desmoglein 3 knockout mice. Plos One. 7: e50024. PMID 23185521 DOI: 10.1371/journal.pone.0050024  0.307
2012 Dusek RL, Bascom JL, Vogel H, Baron S, Borowsky AD, Bissell MJ, Attardi LD. Deficiency of the p53/p63 target Perp alters mammary gland homeostasis and promotes cancer. Breast Cancer Research : Bcr. 14: R65. PMID 22515648 DOI: 10.1186/Bcr3171  0.412
2012 Bieging KT, Attardi LD. Deconstructing p53 transcriptional networks in tumor suppression Trends in Cell Biology. 22: 97-106. PMID 22154076 DOI: 10.1016/J.Tcb.2011.10.006  0.484
2012 Sage J, Attardi L, van Dyke T. Roles of p53 and pRB tumor suppressor networks in human cancer: Insight from studies in the engineered mouse Genetically Engineered Mice For Cancer Research: Design, Analysis, Pathways, Validation and Pre-Clinical Testing. 293-308. DOI: 10.1007/978-0-387-69805-2_14  0.554
2011 Jiang D, Brady CA, Johnson TM, Lee EY, Park EJ, Scott MP, Attardi LD. Full p53 transcriptional activation potential is dispensable for tumor suppression in diverse lineages. Proceedings of the National Academy of Sciences of the United States of America. 108: 17123-8. PMID 21969549 DOI: 10.1073/pnas.1111245108  0.49
2011 Brady CA, Jiang D, Mello SS, Johnson TM, Jarvis LA, Kozak MM, Kenzelmann Broz D, Basak S, Park EJ, McLaughlin ME, Karnezis AN, Attardi LD. Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression. Cell. 145: 571-83. PMID 21565614 DOI: 10.1016/J.Cell.2011.03.035  0.492
2011 Renault VM, Thekkat PU, Hoang KL, White JL, Brady CA, Kenzelmann Broz D, Venturelli OS, Johnson TM, Oskoui PR, Xuan Z, Santo EE, Zhang MQ, Vogel H, Attardi LD, Brunet A. The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor. Oncogene. 30: 3207-21. PMID 21423206 DOI: 10.1038/Onc.2011.35  0.516
2011 Jheon AH, Mostowfi P, Snead ML, Ihrie RA, Sone E, Pramparo T, Attardi LD, Klein OD. PERP regulates enamel formation via effects on cell-cell adhesion and gene expression Journal of Cell Science. 124: 745-754. PMID 21285247 DOI: 10.1242/Jcs.078071  0.668
2011 Le Q, Cao H, Kwok S, Jordan R, Beaudry V, Attardi L, Kong C. Loss of the p53/p63 Target PERP is an Early Event in Oral Cavity Carcinogenesis and Correlates with Higher Local Failure Rate in These Tumors International Journal of Radiation Oncology*Biology*Physics. 81: S756. DOI: 10.1016/J.IJROBP.2011.06.1257  0.339
2010 Beaudry VG, Jiang D, Dusek RL, Park EJ, Knezevich S, Ridd K, Vogel H, Bastian BC, Attardi LD. Loss of the p53/p63 regulated desmosomal protein Perp promotes tumorigenesis. Plos Genetics. 6: e1001168. PMID 20975948 DOI: 10.1371/journal.pgen.1001168  0.398
2010 Brady CA, Attardi LD. p53 at a glance Journal of Cell Science. 123: 2527-2532. PMID 20940128 DOI: 10.1242/jcs.064501  0.403
2010 Huarte M, Guttman M, Feldser D, Garber M, Koziol MJ, Kenzelmann-Broz D, Khalil AM, Zuk O, Amit I, Rabani M, Attardi LD, Regev A, Lander ES, Jacks T, Rinn JL. A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell. 142: 409-19. PMID 20673990 DOI: 10.1016/J.Cell.2010.06.040  0.686
2010 Beaudry VG, Ihrie RA, Jacobs SB, Nguyen B, Pathak N, Park E, Attardi LD. Loss of the desmosomal component perp impairs wound healing in vivo. Dermatology Research and Practice. 2010: 759731. PMID 20628490 DOI: 10.1155/2010/759731  0.609
2010 Brož DK, Attardi LD. In vivo analysis of p53 tumor suppressor function using genetically engineered mouse models Carcinogenesis. 31: 1311-1318. PMID 20097732 DOI: 10.1093/carcin/bgp331  0.499
2009 Beaudry VG, Attardi LD. SKP-ing TAp63: Stem Cell Depletion, Senescence, and Premature Aging Cell Stem Cell. 5: 1-2. PMID 19570504 DOI: 10.1016/j.stem.2009.06.015  0.32
2008 McGowan KA, Li JZ, Park CY, Beaudry V, Tabor HK, Sabnis AJ, Zhang W, Fuchs H, de Angelis MH, Myers RM, Attardi LD, Barsh GS. Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects. Nature Genetics. 40: 963-70. PMID 18641651 DOI: 10.1038/Ng.188  0.305
2008 Basak S, Jacobs SB, Krieg AJ, Pathak N, Zeng Q, Kaldis P, Giaccia AJ, Attardi LD. The metastasis-associated gene Prl-3 is a p53 target involved in cell-cycle regulation. Molecular Cell. 30: 303-14. PMID 18471976 DOI: 10.1016/J.Molcel.2008.04.002  0.46
2008 Johnson TM, Meade K, Pathak N, Marques MR, Attardi LD. Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence Proceedings of the National Academy of Sciences of the United States of America. 105: 1215-1220. PMID 18216268 DOI: 10.1073/pnas.0706764105  0.515
2008 Jarvis L, Johnson T, Attardi L. Full Transcriptional Activation of p53 Target Genes is Not Necessary for Suppression of K-ras Induced Lung Adenocarcinomas International Journal of Radiation Oncology*Biology*Physics. 72: S21-S22. DOI: 10.1016/J.Ijrobp.2008.06.814  0.379
2007 Wijnhoven SWP, Speksnijder EN, Liu X, Zwart E, VanOostrom CTM, Beems RB, Hoogervorst EM, Schaap MM, Attardi LD, Jacks T, Van Steeg H, Jonkers J, De Vries A. Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damage Cancer Research. 67: 4648-4656. PMID 17510390 DOI: 10.1158/0008-5472.Can-06-4681  0.699
2007 Jacobs SB, Basak S, Murray JI, Pathak N, Attardi LD. Siva is an apoptosis-selective p53 target gene important for neuronal cell death. Cell Death and Differentiation. 14: 1374-85. PMID 17464332 DOI: 10.1038/Sj.Cdd.4402128  0.391
2007 Carroll DK, Brugge JS, Attardi LD. p63, cell adhesion and survival Cell Cycle. 6: 255-261. PMID 17297292 DOI: 10.4161/Cc.6.3.3799  0.456
2006 Hammond EM, Mandell DJ, Salim A, Krieg AJ, Johnson TM, Shirazi HA, Attardi LD, Giaccia AJ. Genome-wide analysis of p53 under hypoxic conditions Molecular and Cellular Biology. 26: 3492-3504. PMID 16611991 DOI: 10.1128/Mcb.26.9.3492-3504.2006  0.484
2006 Johnson TM, Attardi LD. Dissecting p53 tumor suppressor function in vivo through the analysis of genetically modified mice Cell Death and Differentiation. 13: 902-908. PMID 16557272 DOI: 10.1038/sj.cdd.4401902  0.334
2006 Ihrie RA, Bronson RT, Attardi LD. Adult mice lacking the p53/p63 target gene Perp are not predisposed to spontaneous tumorigenesis but display features of ectodermal dysplasia syndromes [2] Cell Death and Differentiation. 13: 1614-1618. PMID 16485031 DOI: 10.1038/Sj.Cdd.4401871  0.697
2006 Marques MR, Ihrie RA, Horner JS, Attardi LD. The requirement for Perp in postnatal viability and epithelial integrity reflects an intrinsic role in stratified epithelia Journal of Investigative Dermatology. 126: 69-73. PMID 16417219 DOI: 10.1038/Sj.Jid.5700032  0.63
2005 Marques MR, Horner JS, Ihrie RA, Bronson RT, Attardi LD. Mice lacking the p53/p63 target gene Perp are resistant to papilloma development Cancer Research. 65: 6551-6556. PMID 16061634 DOI: 10.1158/0008-5472.Can-05-0366  0.736
2005 Attardi LD, Donehower LA. Probing p53 biological functions through the use of genetically engineered mouse models Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 576: 4-21. PMID 16038709 DOI: 10.1016/j.mrfmmm.2004.08.022  0.45
2005 Ihrie RA, Attardi LD. A new perp in the lineup: Linking p63 and desmosomal adhesion Cell Cycle. 4: 873-876. PMID 15970683 DOI: 10.4161/Cc.4.7.1836  0.729
2005 Johnson TM, Attardi LD. p53QS: An old mutant teaches us new tricks Cell Cycle. 4: 731-734. PMID 15908788  0.5
2005 Ihrie RA, Marques MR, Nguyen BT, Horner JS, Papazoglu C, Bronson RT, Mills AA, Attardi LD. Perp is a p63-regulated gene essential for epithelial integrity Cell. 120: 843-856. PMID 15797384 DOI: 10.1016/J.Cell.2005.01.008  0.731
2005 Johnson TM, Hammond EM, Giaccia A, Attardi LD. The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality Nature Genetics. 37: 145-152. PMID 15654339 DOI: 10.1038/Ng1498  0.509
2005 Attardi LD. The role of p53-mediated apoptosis as a crucial anti-tumor response to genomic instability: Lessons from mouse models Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 569: 145-157. PMID 15603759 DOI: 10.1016/j.mrfmmm.2004.04.019  0.417
2004 Bruins W, Zwart E, Attardi LD, Iwakuma T, Hoogervorst EM, Beems RB, Miranda B, Van Oostrom CTM, Van Den Berg J, Van Den Aardweg GJ, Lozano G, Van Steeg H, Jacks T, De Vries A. Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389 Molecular and Cellular Biology. 24: 8884-8894. PMID 15456863 DOI: 10.1128/Mcb.24.20.8884-8894.2004  0.699
2004 Beer S, Zetterberg A, Ihrie RA, McTaggart RA, Yang Q, Bradon N, Arvanitis C, Attardi LD, Feng S, Ruebner B, Cardiff RD, Felsher DW. Developmental context determines latency of MYC-induced tumorigenesis Plos Biology. 2. PMID 15455033 DOI: 10.1371/Journal.Pbio.0020332  0.689
2004 Attardi LD, De Vries A, Jacks T. Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer Oncogene. 23: 973-980. PMID 14749764 DOI: 10.1038/Sj.Onc.1207026  0.692
2004 Ihrie RA, Attardi LD. Perp-etrating p53-dependent apoptosis Cell Cycle. 3: 267-269. PMID 14726658 DOI: 10.4161/Cc.3.3.722  0.753
2004 Attardi LD, DePinho RA. Conquering the complexity of p53. Nature Genetics. 36: 7-8. PMID 14702030 DOI: 10.1038/Ng0104-7  0.383
2003 Reczek EE, Flores ER, Tsay AS, Attardi LD, Jacks T. Multiple Response Elements and Differential p53 Binding Control Perp Expression during Apoptosis Molecular Cancer Research. 1: 1048-1057. PMID 14707288  0.727
2003 Ihrie RA, Reczek E, Horner JS, Khachatrian L, Sage J, Jacks T, Attardi LD. Perp Is a Mediator of p53-Dependent Apoptosis in Diverse Cell Types Current Biology. 13: 1985-1990. PMID 14614825 DOI: 10.1016/J.Cub.2003.10.055  0.812
2000 Sage J, Mulligan GJ, Attardi LD, Miller A, Chen S, Williams B, Theodorou E, Jacks T. Targeted disruption of the three Rb-related genes leads to loss of G1 control and immortalization Genes and Development. 14: 3037-3050. PMID 11114892 DOI: 10.1101/Gad.843200  0.76
2000 Attardi LD, Reczek EE, Cosmas C, Demicco EG, McCurrach ME, Lowe SW, Jacks T. PERP, an apoptosis-associated target of p53, in a novel member of the PMP-22/gas3 family Genes and Development. 14: 704-718. PMID 10733530 DOI: 10.1101/Gad.14.6.704  0.772
1999 Attardi LD, Jacks T. The role of p53 in tumour suppression: Lessons from mouse models Cellular and Molecular Life Sciences. 55: 48-63. PMID 10065151 DOI: 10.1007/S000180050269  0.719
1998 Attardi L, Brugarolas J, Heinrichs A. HDAC, a key to pRb tumour suppression? Trends in Cell Biology. 8: 182. DOI: 10.1016/S0962-8924(98)01277-X  0.453
1997 Jones JM, Attardi L, Godley LA, Laucirica R, Medina D, Jacks T, Varmus HE, Donehower LA. Absence of p53 in a mouse mammary tumor model promotes tumor cell proliferation without affecting apoptosis. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 8: 829-38. PMID 9269892  0.731
1996 Attardi LD, Lowe SW, Brugarolas J, Jacks T. Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis Embo Journal. 15: 3693-3701. PMID 8758936  0.529
1996 Attardi LD, Lowe SW, Brugarolas J, Jacks T. Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis. The Embo Journal. 15: 3693-3701. DOI: 10.1002/J.1460-2075.1996.Tb00739.X  0.794
1995 Sah VP, Attardi LD, Mulligan GJ, Williams BO, Bronson RT, Jacks T. A subset of p53-deficient embryos exhibit exencephaly Nature Genetics. 10: 175-180. PMID 7663512 DOI: 10.1038/Ng0695-175  0.722
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