Nicholas Hughes - Publications

Affiliations: 
2008-2011 Radiology Stanford University, Palo Alto, CA 

7/39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Tang R, Shuldiner EG, Kelly M, Murray CW, Hebert JD, Andrejka L, Tsai MK, Hughes NW, Parker MI, Cai H, Li YC, Wahl GM, Dunbrack RL, Jackson PK, Petrov DA, et al. Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth. Nature Cell Biology. PMID 36635501 DOI: 10.1038/s41556-022-01049-w  0.374
2012 Hughes N, Mehta S, Winchester L, Han C, Buffa F, Adams R, Harris A. Abstract P4-01-01: Integrating dynamic magnetic resonance imaging and gene expression profiling reveals novel therapeutic targets in locally advanced breast cancer. Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P4-01-01  0.408
2012 Mehta S, Hughes N, Adams R, Li S, Han C, Kaur K, Taylor N, Padhani A, Makris A, Buffa F, Harris A. Abstract P1-06-01: Upregulation of metabolism as a potential resistance mechanism to bevacizumab in primary breast cancer Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P1-06-01  0.399
2011 Mehta S, Hughes NP, Buffa FM, Li SP, Adams RF, Adwani A, Taylor NJ, Levitt NC, Padhani AR, Makris A, Harris AL. Assessing early therapeutic response to bevacizumab in primary breast cancer using magnetic resonance imaging and gene expression profiles. Journal of the National Cancer Institute. Monographs. 2011: 71-4. PMID 22043045 DOI: 10.1093/jncimonographs/lgr027  0.365
2011 Tseng JR, Stuart D, Aardalen K, Kaplan A, Aziz N, Hughes NP, Gambhir SS. Use of DNA microarray and small animal positron emission tomography in preclinical drug evaluation of RAF265, a novel B-Raf/VEGFR-2 inhibitor. Neoplasia (New York, N.Y.). 13: 266-75. PMID 21390189 DOI: 10.1593/Neo.101466  0.392
2010 Mehta S, Buffa F, Li S, Hughes N, Adams R, Adwani A, Taylor N, Levitt N, Padhani A, Makris A, Harris A. Abstract P2-09-28: Integrated Gene Expression and MRI Analysis To Assess Early Therapeutic Response to Bevacizumab in Primary Breast Cancer Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P2-09-28  0.373
2010 Hughes N, Mehta S, Li S, Taylor J, Adwani A, Buffa F, Levitt N, Makris A, Adams R, Harris A, Padhani A. Abstract P2-02-07: Predicting Response to Bevacizumab Therapy in Primary Breast Cancer Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P2-02-07  0.356
Low-probability matches (unlikely to be authored by this person)
2018 Hughes NP, Xu L, Nielsen CH, Chang E, Hori SS, Natarajan A, Lee S, Kjær A, Kani K, Wang SX, Mallick P, Gambhir SS. A blood biomarker for monitoring response to anti-EGFR therapy. Cancer Biomarkers : Section a of Disease Markers. PMID 29689709 DOI: 10.3233/Cbm-171149  0.278
2021 Cai H, Chew SK, Li C, Tsai MK, Andrejka L, Murray CW, Hughes NW, Shuldiner EG, Ashkin EL, Tang R, Hung KL, Chen LC, Lee SYC, Yousefi M, Lin WY, et al. A functional taxonomy of tumor suppression in oncogenic KRAS-driven lung cancer. Cancer Discovery. PMID 33608386 DOI: 10.1158/2159-8290.CD-20-1325  0.247
2011 Tran PT, Bendapudi PK, Lin HJ, Choi P, Koh S, Chen J, Horng G, Hughes NP, Schwartz LH, Miller VA, Kawashima T, Kitamura T, Paik D, Felsher DW. Survival and death signals can predict tumor response to therapy after oncogene inactivation. Science Translational Medicine. 3: 103ra99. PMID 21974937 DOI: 10.1126/Scitranslmed.3002018  0.241
2024 Hebert JD, Xu H, Tang YJ, Ruiz PA, Detrick C, Wang J, Hughes NW, Donosa O, Andrejka L, Karmakar S, Aboiralor I, Cong L, Sage J, Petrov DA, Winslow MM. Modeling the genomic complexity of human cancer using Cas12a mice. Biorxiv : the Preprint Server For Biology. PMID 38496463 DOI: 10.1101/2024.03.07.583774  0.221
2016 Vilalta M, Hughes NP, Von Eyben R, Giaccia AJ, Graves EE. Patterns of Vasculature in Mouse Models of Lung Cancer Are Dependent on Location. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 27709411 DOI: 10.1007/S11307-016-1010-5  0.195
2015 Wang T, Birsoy K, Hughes NW, Krupczak KM, Post Y, Wei JJ, Lander ES, Sabatini DM. Identification and characterization of essential genes in the human genome. Science (New York, N.Y.). PMID 26472758 DOI: 10.1126/Science.Aac7041  0.161
2017 Wang T, Yu H, Hughes NW, Liu B, Kendirli A, Klein K, Chen WW, Lander ES, Sabatini DM. Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras. Cell. PMID 28162770 DOI: 10.1016/j.cell.2017.01.013  0.158
2022 Wang C, Xia Q, Zhang Q, Qu Y, Su S, Cheng JKW, Hughes NW, Cong L. CRISPR-Cas12a System With Synergistic Phage Recombination Proteins for Multiplex Precision Editing in Human Cells. Frontiers in Cell and Developmental Biology. 9: 719705. PMID 35774104 DOI: 10.3389/fcell.2021.719705  0.145
2018 Allsop MJ, Wright-Hughes A, Black K, Hartley S, Fletcher M, Ziegler LE, Bewick BM, Meads D, Hughes ND, Closs SJ, Hulme C, Taylor S, Flemming K, Hackett J, O'Dwyer JL, et al. Improving the management of pain from advanced cancer in the community: study protocol for a pragmatic multicentre randomised controlled trial. Bmj Open. 8: e021965. PMID 29572400 DOI: 10.1136/bmjopen-2018-021965  0.141
2021 Wang C, Cheng JKW, Zhang Q, Hughes NW, Xia Q, Winslow MM, Cong L. Microbial single-strand annealing proteins enable CRISPR gene-editing tools with improved knock-in efficiencies and reduced off-target effects. Nucleic Acids Research. PMID 33619540 DOI: 10.1093/nar/gkaa1264  0.112
2016 Hughes ND, Closs SJ, Flemming K, Bennett MI. Supporting self-management of pain by patients with advanced cancer: views of palliative care professionals. Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer. PMID 27557834 DOI: 10.1007/s00520-016-3372-2  0.104
2022 Wang C, Qu Y, Cheng JKW, Hughes NW, Zhang Q, Wang M, Cong L. dCas9-based gene editing for cleavage-free genomic knock-in of long sequences. Nature Cell Biology. 24: 268-278. PMID 35145221 DOI: 10.1038/s41556-021-00836-1  0.102
2022 Hughes NW, Qu Y, Zhang J, Tang W, Pierce J, Wang C, Agrawal A, Morri M, Neff N, Winslow MM, Wang M, Cong L. Machine-learning-optimized Cas12a barcoding enables the recovery of single-cell lineages and transcriptional profiles. Molecular Cell. PMID 35752172 DOI: 10.1016/j.molcel.2022.06.001  0.1
2014 Hughes NJ, Hunt JJ, Cloherty SL, Ibbotson MR, Sengpiel F, Goodhill GJ. Stripe-rearing changes multiple aspects of the structure of primary visual cortex. Neuroimage. 95: 305-19. PMID 24657308 DOI: 10.1016/J.Neuroimage.2014.03.031  0.072
2016 Avitan L, Pujic Z, Hughes NJ, Scott EK, Goodhill GJ. Limitations of Neural Map Topography for Decoding Spatial Information. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 5385-96. PMID 27170134 DOI: 10.1523/Jneurosci.0385-16.2016  0.07
2016 Hughes NJ, Goodhill GJ. Estimating Cortical Feature Maps with Dependent Gaussian Processes. Ieee Transactions On Pattern Analysis and Machine Intelligence. PMID 27831860 DOI: 10.1109/Tpami.2016.2624295  0.041
2016 Cloherty SL, Hughes NJ, Hietanen MA, Bhagavatula PS, Goodhill GJ, Ibbotson MR. Sensory experience modifies feature map relationships in visual cortex. Elife. 5. PMID 27310531 DOI: 10.7554/Elife.13911  0.04
2018 Stewart A, Hughes ND, Simkin S, Locock L, Ferrey A, Kapur N, Gunnell D, Hawton K. Navigating an unfamiliar world: how parents of young people who self-harm experience support and treatment. Child and Adolescent Mental Health. 23: 78-84. PMID 32677335 DOI: 10.1111/Camh.12205  0.035
2016 Ferrey AE, Hughes ND, Simkin S, Locock L, Stewart A, Kapur N, Gunnell D, Hawton K. The impact of self-harm by young people on parents and families: a qualitative study. Bmj Open. 6: e009631. PMID 26739734 DOI: 10.1136/Bmjopen-2015-009631  0.032
2020 Cathcart J, Johnson RC, Hughes N, Patel M. Diagnostic difficulties in a patient with multiple sclerosis who presents with cranial nerve palsies: an unusual complication of dental work. Bmj Case Reports. 13. PMID 33127721 DOI: 10.1136/bcr-2019-232903  0.031
2019 Mazanderani F, Hughes N, Hardy C, Sillence E, Powell J. Health information work and the enactment of care in couples and families affected by Multiple Sclerosis. Sociology of Health & Illness. PMID 30677163 DOI: 10.1111/1467-9566.12842  0.028
2007 Hughes NJ, Pullin RD, Sanganee MJ, Sellars JD, Steel PG, Turner MJ. Hosomi-Sakurai reactions of silacyclohexenes. Organic & Biomolecular Chemistry. 5: 2841-8. PMID 17700853 DOI: 10.1039/B709318G  0.028
2016 Ferrey AE, Hughes ND, Simkin S, Locock L, Stewart A, Kapur N, Gunnell D, Hawton K. Changes in parenting strategies after a young person's self-harm: a qualitative study. Child and Adolescent Psychiatry and Mental Health. 10: 20. PMID 27375774 DOI: 10.1186/S13034-016-0110-Y  0.026
2015 Ferrey AE, Hawton K, Simkin S, Hughes N, Stewart A, Locock L. "As a parent, there is no rulebook": a new resource for parents and carers of young people who self-harm. The Lancet. Psychiatry. 2: 577-9. PMID 26303538 DOI: 10.1016/S2215-0366(15)00182-0  0.022
2021 Hughes NW, Cong L. A CRISPR Landing for Genome Rewriting at Locus-Scale. The Crispr Journal. 4: 163-166. PMID 33876954 DOI: 10.1089/crispr.2021.29124.lec  0.022
2015 Hughes NS, Haselgrove A, Tovey MS, Khokhar WA, Husain M, Osman-Hicks VC. Exit examination: a survey of UK psychiatrists' views. Bjpsych Bulletin. 39: 254-9. PMID 26755972 DOI: 10.1192/pb.bp.114.046805  0.022
2008 Mansor S, Hughes NP, Noble JA. Wall motion classification of stress echocardiography based on combined rest-and-stress data. Medical Image Computing and Computer-Assisted Intervention : Miccai ... International Conference On Medical Image Computing and Computer-Assisted Intervention. 11: 139-46. PMID 18982599  0.019
2015 Hughes NJ, Goodhill GJ. Optimizing the representation of orientation preference maps in visual cortex. Neural Computation. 27: 32-41. PMID 25380336 DOI: 10.1162/Neco_A_00687  0.017
2015 Hughes ND, Locock L, Simkin S, Stewart A, Ferrey AE, Gunnell D, Kapur N, Hawton K. Making Sense of an Unknown Terrain: How Parents Understand Self-Harm in Young People. Qualitative Health Research. PMID 26369673 DOI: 10.1177/1049732315603032  0.016
2010 McNulty K, Massouh L, Hughes NC, Ho TB. Incidental findings of solitary pulmonary nodules on computed tomographic pulmonary angiography: a hidden workload. Clinical Medicine (London, England). 10: 100. PMID 20408324  0.01
2009 Strachan IG, Hughes NP, Poonawala MH, Mason JW, Tarassenko L. Automated QT analysis that learns from cardiologist annotations. Annals of Noninvasive Electrocardiology : the Official Journal of the International Society For Holter and Noninvasive Electrocardiology, Inc. 14: S9-21. PMID 19143745 DOI: 10.1111/j.1542-474X.2008.00259.x  0.01
2004 Hughes NP, Roberts SJ, Tarassenko L. Semi-supervised learning of probabilistic models for ECG segmentation. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 1: 434-7. PMID 17271705 DOI: 10.1109/IEMBS.2004.1403187  0.01
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