| Year |
Citation |
Score |
| 2023 |
Dan Y, Radic N, Gay M, Fernández-Torras A, Arauz G, Vilaseca M, Aloy P, Canovas B, Nebreda A. Characterization of p38α signaling networks in cancer cells using quantitative proteomics and phosphoproteomics. Molecular & Cellular Proteomics : McP. 100527. PMID 36894123 DOI: 10.1016/j.mcpro.2023.100527 |
0.354 |
|
| 2022 |
Boccuni L, Podgorschek E, Schmiedeberg M, Platanitis E, Traxler P, Fischer P, Schirripa A, Novoszel P, Nebreda AR, Arthur JSC, Fortelny N, Farlik M, Sexl V, Bock C, Sibilia M, et al. Stress signaling boosts interferon-induced gene transcription in macrophages. Science Signaling. 15: eabq5389. PMID 36512641 DOI: 10.1126/scisignal.abq5389 |
0.334 |
|
| 2021 |
Gutierrez-Prat N, Cubillos-Rojas M, Cánovas B, Kuzmanic A, Gupta J, Igea A, Llonch E, Gaestel M, Nebreda AR. MK2 degradation as a sensor of signal intensity that controls stress-induced cell fate. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34272277 DOI: 10.1073/pnas.2024562118 |
0.317 |
|
| 2021 |
Canovas B, Nebreda AR. Diversity and versatility of p38 kinase signalling in health and disease. Nature Reviews. Molecular Cell Biology. 22: 346-366. PMID 33504982 DOI: 10.1038/s41580-020-00322-w |
0.342 |
|
| 2020 |
Gonzalez L, Nebreda AR. RINGO/Speedy proteins, a family of non-canonical activators of CDK1 and CDK2. Seminars in Cell & Developmental Biology. PMID 32317145 DOI: 10.1016/j.semcdb.2020.03.010 |
0.428 |
|
| 2019 |
Casadomé-Perales Á, Matteis L, Alleva M, Infantes-Rodríguez C, Palomares-Pérez I, Saito T, Saido TC, Esteban JA, Nebreda AR, de la Fuente JM, Dotti CG. Inhibition of p38 MAPK in the brain through nasal administration of p38 inhibitor loaded in chitosan nanocapsules. Nanomedicine (London, England). PMID 31456488 DOI: 10.2217/Nnm-2018-0496 |
0.326 |
|
| 2019 |
Slobodnyuk K, Radic N, Ivanova S, Llado A, Trempolec N, Zorzano A, Nebreda AR. Autophagy-induced senescence is regulated by p38α signaling. Cell Death & Disease. 10: 376. PMID 31092814 DOI: 10.1038/s41419-019-1607-0 |
0.324 |
|
| 2017 |
Salvador-Bernáldez M, Mateus SB, Del Barco Barrantes I, Arthur SC, Martínez-A C, Nebreda AR, Salvador JM. p38α regulates cytokine-induced IFNγ secretion via the Mnk1/eIF4E pathway in Th1 cells. Immunology and Cell Biology. 95: 814-823. PMID 28611474 DOI: 10.1038/icb.2017.51 |
0.313 |
|
| 2017 |
Kuzmanic A, Sutto L, Saladino G, Nebreda AR, Gervasio FL, Orozco M. Changes in the free-energy landscape of p38α MAP kinase through its canonical activation and binding events as studied by enhanced molecular dynamics simulations. Elife. 6. PMID 28445123 DOI: 10.7554/eLife.22175 |
0.347 |
|
| 2017 |
Terriente-Félix A, Pérez L, Bray SJ, Nebreda AR, Milán M. Drosophila model of myeloproliferative neoplasm reveals a feed-forward loop in the JAK pathway mediated by p38 MAPK signalling. Disease Models & Mechanisms. PMID 28237966 DOI: 10.1242/dmm.028118 |
0.404 |
|
| 2016 |
Galanos P, Vougas K, Walter D, Polyzos A, Maya-Mendoza A, Haagensen EJ, Kokkalis A, Roumelioti FM, Gagos S, Tzetis M, Canovas B, Igea A, Ahuja AK, Zellweger R, Havaki S, ... ... Nebreda A, et al. Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing. Nature Cell Biology. PMID 27323328 DOI: 10.1038/Ncb3378 |
0.33 |
|
| 2016 |
Mikolcevic P, Isoda M, Shibuya H, del Barco Barrantes I, Igea A, Suja JA, Shackleton S, Watanabe Y, Nebreda AR. Essential role of the Cdk2 activator RingoA in meiotic telomere tethering to the nuclear envelope. Nature Communications. 7: 11084. PMID 27025256 DOI: 10.1038/ncomms11084 |
0.312 |
|
| 2015 |
Igea A, Nebreda AR. The Stress Kinase p38α as a Target for Cancer Therapy. Cancer Research. 75: 3997-4002. PMID 26377941 DOI: 10.1158/0008-5472.CAN-15-0173 |
0.3 |
|
| 2015 |
Gupta J, Nebreda AR. Roles of p38α mitogen-activated protein kinase in mouse models of inflammatory diseases and cancer Febs Journal. 282: 1841-1857. PMID 25728574 DOI: 10.1111/febs.13250 |
0.331 |
|
| 2013 |
Pereira L, Igea A, Canovas B, Dolado I, Nebreda AR. Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK. Embo Molecular Medicine. 5: 1759-74. PMID 24115572 DOI: 10.1002/emmm.201302732 |
0.377 |
|
| 2013 |
Tormos AM, Taléns-Visconti R, Nebreda AR, Sastre J. p38 MAPK: a dual role in hepatocyte proliferation through reactive oxygen species. Free Radical Research. 47: 905-16. PMID 23906070 DOI: 10.3109/10715762.2013.821200 |
0.355 |
|
| 2013 |
Amata I, Maffei M, Igea A, Gay M, Vilaseca M, Nebreda AR, Pons M. Multi-phosphorylation of the intrinsically disordered unique domain of c-Src studied by in-cell and real-time NMR spectroscopy. Chembiochem : a European Journal of Chemical Biology. 14: 1820-7. PMID 23744817 DOI: 10.1002/cbic.201300139 |
0.43 |
|
| 2013 |
Trempolec N, Dave-Coll N, Nebreda AR. SnapShot: p38 MAPK substrates. Cell. 152: 924-924.e1. PMID 23415236 DOI: 10.1016/j.cell.2013.01.047 |
0.316 |
|
| 2013 |
Trempolec N, Dave-Coll N, Nebreda AR. SnapShot: p38 MAPK signaling. Cell. 152: 656-656.e1. PMID 23374355 DOI: 10.1016/j.cell.2013.01.029 |
0.338 |
|
| 2012 |
Warr N, Carre GA, Siggers P, Faleato JV, Brixey R, Pope M, Bogani D, Childers M, Wells S, Scudamore CL, Tedesco M, del Barco Barrantes I, Nebreda AR, Trainor PA, Greenfield A. Gadd45γ and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression. Developmental Cell. 23: 1020-31. PMID 23102580 DOI: 10.1016/J.Devcel.2012.09.016 |
0.396 |
|
| 2012 |
Llopis A, Salvador N, Ercilla A, Guaita-Esteruelas S, Barrantes Idel B, Gupta J, Gaestel M, Davis RJ, Nebreda AR, Agell N. The stress-activated protein kinases p38α/β and JNK1/2 cooperate with Chk1 to inhibit mitotic entry upon DNA replication arrest. Cell Cycle (Georgetown, Tex.). 11: 3627-37. PMID 22935704 DOI: 10.4161/Cc.21917 |
0.369 |
|
| 2012 |
Furlan A, Lamballe F, Stagni V, Hussain A, Richelme S, Prodosmo A, Moumen A, Brun C, Del Barco Barrantes I, Arthur JS, Koleske AJ, Nebreda AR, Barilà D, Maina F. Met acts through Abl to regulate p53 transcriptional outcomes and cell survival in the developing liver. Journal of Hepatology. 57: 1292-8. PMID 22889954 DOI: 10.1016/j.jhep.2012.07.044 |
0.332 |
|
| 2012 |
Joaquin M, Gubern A, González-Nuñez D, Josué Ruiz E, Ferreiro I, de Nadal E, Nebreda AR, Posas F. The p57 CDKi integrates stress signals into cell-cycle progression to promote cell survival upon stress. The Embo Journal. 31: 2952-64. PMID 22569127 DOI: 10.1038/emboj.2012.122 |
0.401 |
|
| 2012 |
del Barco Barrantes I, Nebreda AR. Roles of p38 MAPKs in invasion and metastasis. Biochemical Society Transactions. 40: 79-84. PMID 22260669 DOI: 10.1042/BST20110676 |
0.41 |
|
| 2012 |
Ho KK, McGuire VA, Koo CY, Muir KW, de Olano N, Maifoshie E, Kelly DJ, McGovern UB, Monteiro LJ, Gomes AR, Nebreda AR, Campbell DG, Arthur JS, Lam EW. Phosphorylation of FOXO3a on Ser-7 by p38 promotes its nuclear localization in response to doxorubicin. The Journal of Biological Chemistry. 287: 1545-55. PMID 22128155 DOI: 10.1074/jbc.M111.284224 |
0.492 |
|
| 2011 |
Ronkina N, Menon MB, Schwermann J, Arthur JS, Legault H, Telliez JB, Kayyali US, Nebreda AR, Kotlyarov A, Gaestel M. Stress induced gene expression: a direct role for MAPKAP kinases in transcriptional activation of immediate early genes. Nucleic Acids Research. 39: 2503-18. PMID 21109534 DOI: 10.1093/nar/gkq1178 |
0.42 |
|
| 2010 |
Cuadrado A, Nebreda AR. Mechanisms and functions of p38 MAPK signalling. The Biochemical Journal. 429: 403-17. PMID 20626350 DOI: 10.1042/BJ20100323 |
0.47 |
|
| 2010 |
Mourón S, de Cárcer G, Seco E, Fernández-Miranda G, Malumbres M, Nebreda AR. RINGO C is required to sustain the spindle-assembly checkpoint. Journal of Cell Science. 123: 2586-95. PMID 20605920 DOI: 10.1242/jcs.059964 |
0.321 |
|
| 2010 |
Ruiz EJ, Vilar M, Nebreda AR. A two-step inactivation mechanism of Myt1 ensures CDK1/cyclin B activation and meiosis I entry. Current Biology : Cb. 20: 717-23. PMID 20362450 DOI: 10.1016/j.cub.2010.02.050 |
0.497 |
|
| 2010 |
Ferreiro I, Joaquin M, Islam A, Gomez-Lopez G, Barragan M, Lombardía L, Domínguez O, Pisano DG, Lopez-Bigas N, Nebreda AR, Posas F. Whole genome analysis of p38 SAPK-mediated gene expression upon stress. Bmc Genomics. 11: 144. PMID 20187982 DOI: 10.1186/1471-2164-11-144 |
0.306 |
|
| 2010 |
Lemaire M, Ducommun B, Nebreda AR. UV-induced downregulation of the CDC25B protein in human cells. Febs Letters. 584: 1199-204. PMID 20176018 DOI: 10.1016/j.febslet.2010.02.043 |
0.416 |
|
| 2009 |
Wagner EF, Nebreda AR. Signal integration by JNK and p38 MAPK pathways in cancer development. Nature Reviews. Cancer. 9: 537-49. PMID 19629069 DOI: 10.1038/Nrc2694 |
0.439 |
|
| 2009 |
Dinarina A, Santamaria PG, Nebreda AR. Cell cycle regulation of the mammalian CDK activator RINGO/Speedy A. Febs Letters. 583: 2772-8. PMID 19622356 DOI: 10.1016/j.febslet.2009.07.028 |
0.418 |
|
| 2009 |
Lafarga V, Cuadrado A, Lopez de Silanes I, Bengoechea R, Fernandez-Capetillo O, Nebreda AR. p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint. Molecular and Cellular Biology. 29: 4341-51. PMID 19528229 DOI: 10.1128/Mcb.00210-09 |
0.429 |
|
| 2009 |
Git A, Allison R, Perdiguero E, Nebreda AR, Houliston E, Standart N. Vg1RBP phosphorylation by Erk2 MAP kinase correlates with the cortical release of Vg1 mRNA during meiotic maturation of Xenopus oocytes. Rna (New York, N.Y.). 15: 1121-33. PMID 19376927 DOI: 10.1261/rna.1195709 |
0.447 |
|
| 2009 |
Swat A, Dolado I, Rojas JM, Nebreda AR. Cell density-dependent inhibition of epidermal growth factor receptor signaling by p38alpha mitogen-activated protein kinase via Sprouty2 downregulation. Molecular and Cellular Biology. 29: 3332-43. PMID 19364817 DOI: 10.1128/MCB.01955-08 |
0.405 |
|
| 2008 |
Ruiz EJ, Hunt T, Nebreda AR. Meiotic inactivation of Xenopus Myt1 by CDK/XRINGO, but not CDK/cyclin, via site-specific phosphorylation. Molecular Cell. 32: 210-20. PMID 18951089 DOI: 10.1016/j.molcel.2008.08.029 |
0.477 |
|
| 2008 |
Hernández-Torres F, MartÃnez-Fernández S, Zuluaga S, Nebreda A, Porras A, Aránega AE, Navarro F. A role for p38alpha mitogen-activated protein kinase in embryonic cardiac differentiation. Febs Letters. 582: 1025-31. PMID 18314011 DOI: 10.1016/j.febslet.2008.02.050 |
0.313 |
|
| 2008 |
Dinarina A, Ruiz EJ, O'Loghlen A, Mouron S, Perez L, Nebreda AR. Negative regulation of cell-cycle progression by RINGO/Speedy E. The Biochemical Journal. 410: 535-42. PMID 18072937 DOI: 10.1042/BJ20071453 |
0.336 |
|
| 2007 |
Cuadrado A, Nebreda AR. New insights into RSK activation and hematopoietic cancer. Cancer Cell. 12: 187-9. PMID 17785199 DOI: 10.1016/j.ccr.2007.08.017 |
0.465 |
|
| 2007 |
Lafarga V, Cuadrado A, Nebreda AR. p18(Hamlet) mediates different p53-dependent responses to DNA-damage inducing agents. Cell Cycle (Georgetown, Tex.). 6: 2319-22. PMID 17700068 |
0.403 |
|
| 2007 |
Zuluaga S, Gutiérrez-Uzquiza A, Bragado P, Alvarez-Barrientos A, Benito M, Nebreda AR, Porras A. p38alpha MAPK can positively or negatively regulate Rac-1 activity depending on the presence of serum. Febs Letters. 581: 3819-25. PMID 17658519 DOI: 10.1016/j.febslet.2007.06.078 |
0.353 |
|
| 2007 |
Casado-Vela J, Ruiz EJ, Nebreda AR, Casal JI. A combination of neutral loss and targeted product ion scanning with two enzymatic digestions facilitates the comprehensive mapping of phosphorylation sites. Proteomics. 7: 2522-9. PMID 17610206 DOI: 10.1002/pmic.200700026 |
0.348 |
|
| 2007 |
Cuadrado A, Lafarga V, Cheung PC, Dolado I, Llanos S, Cohen P, Nebreda AR. A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis. The Embo Journal. 26: 2115-26. PMID 17380123 DOI: 10.1038/Sj.Emboj.7601657 |
0.402 |
|
| 2007 |
Zuluaga S, Alvarez-Barrientos A, Gutiérrez-Uzquiza A, Benito M, Nebreda AR, Porras A. Negative regulation of Akt activity by p38alpha MAP kinase in cardiomyocytes involves membrane localization of PP2A through interaction with caveolin-1. Cellular Signalling. 19: 62-74. PMID 16844343 DOI: 10.1016/j.cellsig.2006.05.032 |
0.405 |
|
| 2006 |
Gutierrez GJ, Vögtlin A, Castro A, Ferby I, Salvagiotto G, Ronai Z, Lorca T, Nebreda AR. Meiotic regulation of the CDK activator RINGO/Speedy by ubiquitin-proteasome-mediated processing and degradation. Nature Cell Biology. 8: 1084-94. PMID 16964245 DOI: 10.1038/Ncb1472 |
0.437 |
|
| 2006 |
Lemaire M, Froment C, Boutros R, Mondesert O, Nebreda AR, Monsarrat B, Ducommun B. CDC25B phosphorylation by p38 and MK-2. Cell Cycle (Georgetown, Tex.). 5: 1649-53. PMID 16861915 DOI: 10.4161/cc.5.15.3006 |
0.457 |
|
| 2006 |
Giafis N, Katsoulidis E, Sassano A, Tallman MS, Higgins LS, Nebreda AR, Davis RJ, Platanias LC. Role of the p38 mitogen-activated protein kinase pathway in the generation of arsenic trioxide-dependent cellular responses. Cancer Research. 66: 6763-71. PMID 16818652 DOI: 10.1158/0008-5472.Can-05-3699 |
0.409 |
|
| 2006 |
Ventura JJ, Nebreda AR. Protein kinases and phosphatases as therapeutic targets in cancer. Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 8: 153-60. PMID 16648114 DOI: 10.1007/s12094-006-0005-0 |
0.379 |
|
| 2006 |
Rousseau S, Dolado I, Beardmore V, Shpiro N, Marquez R, Nebreda AR, Arthur JS, Case LM, Tessier-Lavigne M, Gaestel M, Cuenda A, Cohen P. CXCL12 and C5a trigger cell migration via a PAK1/2-p38alpha MAPK-MAPKAP-K2-HSP27 pathway. Cellular Signalling. 18: 1897-905. PMID 16574378 DOI: 10.1016/J.Cellsig.2006.02.006 |
0.346 |
|
| 2006 |
Ambrosino C, Iwata T, Scafoglio C, Mallardo M, Klein R, Nebreda AR. TEF-1 and C/EBPbeta are major p38alpha MAPK-regulated transcription factors in proliferating cardiomyocytes. The Biochemical Journal. 396: 163-72. PMID 16492136 DOI: 10.1042/Bj20051502 |
0.31 |
|
| 2006 |
Nebreda AR. CDK activation by non-cyclin proteins. Current Opinion in Cell Biology. 18: 192-8. PMID 16488127 DOI: 10.1016/J.CEB.2006.01.001 |
0.464 |
|
| 2005 |
Lluís F, Perdiguero E, Nebreda AR, Muñoz-Cánoves P. Regulation of skeletal muscle gene expression by p38 MAP kinases. Trends in Cell Biology. 16: 36-44. PMID 16325404 DOI: 10.1016/J.TCB.2005.11.002 |
0.315 |
|
| 2005 |
Macé G, Miaczynska M, Zerial M, Nebreda AR. Phosphorylation of EEA1 by p38 MAP kinase regulates mu opioid receptor endocytosis. The Embo Journal. 24: 3235-46. PMID 16138080 DOI: 10.1038/Sj.Emboj.7600799 |
0.406 |
|
| 2005 |
Faust D, Dolado I, Cuadrado A, Oesch F, Weiss C, Nebreda AR, Dietrich C. p38alpha MAPK is required for contact inhibition. Oncogene. 24: 7941-5. PMID 16027723 DOI: 10.1038/Sj.Onc.1208948 |
0.307 |
|
| 2005 |
Emerling BM, Platanias LC, Black E, Nebreda AR, Davis RJ, Chandel NS. Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling. Molecular and Cellular Biology. 25: 4853-62. PMID 15923604 DOI: 10.1128/Mcb.25.12.4853-4862.2005 |
0.352 |
|
| 2005 |
Dinarina A, Perez LH, Davila A, Schwab M, Hunt T, Nebreda AR. Characterization of a new family of cyclin-dependent kinase activators. The Biochemical Journal. 386: 349-55. PMID 15574121 DOI: 10.1042/BJ20041779 |
0.456 |
|
| 2004 |
Perdiguero E, Nebreda AR. Regulation of Cdc25C activity during the meiotic G2/M transition. Cell Cycle (Georgetown, Tex.). 3: 733-7. PMID 15136768 |
0.529 |
|
| 2004 |
Suelves M, Lluís F, Ruiz V, Nebreda AR, Muñoz-Cánoves P. Phosphorylation of MRF4 transactivation domain by p38 mediates repression of specific myogenic genes. The Embo Journal. 23: 365-75. PMID 14739931 DOI: 10.1038/sj.emboj.7600056 |
0.365 |
|
| 2004 |
Cheung PCF, Nebreda AR, Cohen P. TAB3, a new binding partner of the protein kinase TAK1 Biochemical Journal. 378: 27-34. PMID 14670075 DOI: 10.1042/Bj20031794 |
0.433 |
|
| 2004 |
Porras A, Zuluaga S, Black E, Valladares A, Alvarez AM, Ambrosino C, Benito M, Nebreda AR. P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli. Molecular Biology of the Cell. 15: 922-33. PMID 14617800 DOI: 10.1091/mbc.E03-08-0592 |
0.423 |
|
| 2004 |
Li Y, Sassano A, Majchrzak B, Deb DK, Levy DE, Gaestel M, Nebreda AR, Fish EN, Platanias LC. Role of p38alpha Map kinase in Type I interferon signaling. The Journal of Biological Chemistry. 279: 970-9. PMID 14578350 DOI: 10.1074/Jbc.M309927200 |
0.454 |
|
| 2003 |
Cheung PCF, Campbell DG, Nebreda AR, Cohen P. Feedback control of the protein kinase TAK1 by SAPK2a/p38α The Embo Journal. 22: 5793-5805. PMID 14592977 DOI: 10.1093/Emboj/Cdg552 |
0.394 |
|
| 2003 |
Perdiguero E, Pillaire MJ, Bodart JF, Hennersdorf F, Frödin M, Duesbery NS, Alonso G, Nebreda AR. Xp38gamma/SAPK3 promotes meiotic G(2)/M transition in Xenopus oocytes and activates Cdc25C. The Embo Journal. 22: 5746-56. PMID 14592973 DOI: 10.1093/emboj/cdg559 |
0.542 |
|
| 2003 |
Merckx A, Le Roch K, Nivez MP, Dorin D, Alano P, Gutierrez GJ, Nebreda AR, Goldring D, Whittle C, Patterson S, Chakrabarti D, Doerig C. Identification and initial characterization of three novel cyclin-related proteins of the human malaria parasite Plasmodium falciparum. The Journal of Biological Chemistry. 278: 39839-50. PMID 12869562 DOI: 10.1074/jbc.M301625200 |
0.414 |
|
| 2003 |
Biondi RM, Nebreda AR. Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions. The Biochemical Journal. 372: 1-13. PMID 12600273 DOI: 10.1042/BJ20021641 |
0.454 |
|
| 2003 |
Ambrosino C, Mace G, Galban S, Fritsch C, Vintersten K, Black E, Gorospe M, Nebreda AR. Negative feedback regulation of MKK6 mRNA stability by p38alpha mitogen-activated protein kinase. Molecular and Cellular Biology. 23: 370-81. PMID 12482988 DOI: 10.1128/MCB.23.1.370-381.2003 |
0.348 |
|
| 2002 |
Ramsauer K, Sadzak I, Porras A, Pilz A, Nebreda AR, Decker T, Kovarik P. p38 MAPK enhances STAT1-dependent transcription independently of Ser-727 phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 99: 12859-64. PMID 12232043 DOI: 10.1073/Pnas.192264999 |
0.478 |
|
| 2002 |
Bulavin DV, Demidov ON, Saito S, Kauraniemi P, Phillips C, Amundson SA, Ambrosino C, Sauter G, Nebreda AR, Anderson CW, Kallioniemi A, Fornace AJ, Appella E. Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity Nature Genetics. 31: 210-215. PMID 12021785 DOI: 10.1038/Ng894 |
0.392 |
|
| 2002 |
Schmitt A, Gutierrez GJ, Lénárt P, Ellenberg J, Nebreda AR. Histone H3 phosphorylation during Xenopus oocyte maturation: regulation by the MAP kinase/p90Rsk pathway and uncoupling from DNA condensation. Febs Letters. 518: 23-8. PMID 11997011 DOI: 10.1016/S0014-5793(02)02630-3 |
0.4 |
|
| 2002 |
Bodart JF, Gutierrez DV, Nebreda AR, Buckner BD, Resau JR, Duesbery NS. Characterization of MPF and MAPK activities during meiotic maturation of Xenopus tropicalis oocytes. Developmental Biology. 245: 348-61. PMID 11977986 DOI: 10.1006/dbio.2002.0647 |
0.453 |
|
| 2002 |
Riechmann V, Gutierrez GJ, Filardo P, Nebreda AR, Ephrussi A. Par-1 regulates stability of the posterior determinant Oskar by phosphorylation. Nature Cell Biology. 4: 337-42. PMID 11951092 DOI: 10.1038/ncb782 |
0.372 |
|
| 2002 |
Schmitt A, Nebreda AR. Inhibition of Xenopus oocyte meiotic maturation by catalytically inactive protein kinase A. Proceedings of the National Academy of Sciences of the United States of America. 99: 4361-6. PMID 11904361 DOI: 10.1073/pnas.022056399 |
0.433 |
|
| 2002 |
Ambrosino C, Nebreda AR. Cell cycle regulation by p38 MAP kinases. Biology of the Cell. 93: 47-51. PMID 11730321 DOI: 10.1016/S0248-4900(01)01124-8 |
0.495 |
|
| 2001 |
Karaiskou A, Perez LH, Ferby I, Ozon R, Jessus C, Nebreda AR. Differential regulation of Cdc2 and Cdk2 by RINGO and cyclins. The Journal of Biological Chemistry. 276: 36028-34. PMID 11461916 DOI: 10.1074/jbc.M104722200 |
0.517 |
|
| 2001 |
Ogimoto M, Arimura Y, Katagiri T, Mitomo K, Woodgett JR, Nebreda AR, Mizuno K, Yakura H. Opposing regulation of B cell receptor-induced activation of mitogen-activated protein kinases by CD45 Febs Letters. 490: 97-101. PMID 11172819 DOI: 10.1016/S0014-5793(00)02416-9 |
0.454 |
|
| 2001 |
Pillaire MJ, Nebreda AR, Darbon JM. Cisplatin and UV radiation induce activation of the stress-activated protein kinase p38gamma in human melanoma cells. Biochemical and Biophysical Research Communications. 278: 724-8. PMID 11095975 DOI: 10.1006/BBRC.2000.3877 |
0.424 |
|
| 2000 |
Nebreda AR, Ferby I. Regulation of the meiotic cell cycle in oocytes. Current Opinion in Cell Biology. 12: 666-75. PMID 11063930 DOI: 10.1016/S0955-0674(00)00150-2 |
0.315 |
|
| 2000 |
Alonso G, Ambrosino C, Jones M, Nebreda AR. Differential activation of p38 mitogen-activated protein kinase isoforms depending on signal strength. The Journal of Biological Chemistry. 275: 40641-8. PMID 11010976 DOI: 10.1074/Jbc.M007835200 |
0.466 |
|
| 2000 |
Nebreda AR, Porras A. p38 MAP kinases: beyond the stress response. Trends in Biochemical Sciences. 25: 257-60. PMID 10838561 DOI: 10.1016/S0968-0004(00)01595-4 |
0.38 |
|
| 2000 |
Palmer A, Nebreda AR. The activation of MAP kinase and p34cdc2/cyclin B during the meiotic maturation of Xenopus oocytes. Progress in Cell Cycle Research. 4: 131-43. PMID 10740821 DOI: 10.1007/978-1-4615-4253-7_12 |
0.518 |
|
| 2000 |
Reynolds CH, Betts JC, Blackstock WP, Nebreda AR, Anderton BH. Phosphorylation sites on tau identified by nanoelectrospray mass spectrometry: differences in vitro between the mitogen-activated protein kinases ERK2, c-Jun N-terminal kinase and P38, and glycogen synthase kinase-3beta. Journal of Neurochemistry. 74: 1587-95. PMID 10737616 DOI: 10.1046/j.1471-4159.2000.0741587.x |
0.498 |
|
| 2000 |
Adams RH, Porras A, Alonso G, Jones M, Vintersten K, Panelli S, Valladares A, Perez L, Klein R, Nebreda AR. Essential Role of p38α MAP Kinase in Placental but Not Embryonic Cardiovascular Development Molecular Cell. 6: 109-116. DOI: 10.1016/S1097-2765(05)00014-6 |
0.369 |
|
| 1999 |
Nebreda AR, Gavin AC. Perspectives: signal transduction. Cell survival demands some Rsk. Science (New York, N.Y.). 286: 1309-10. PMID 10610536 DOI: 10.1126/SCIENCE.286.5443.1309 |
0.477 |
|
| 1999 |
Gavin AC, Ni Ainle A, Chierici E, Jones M, Nebreda AR. A p90(rsk) mutant constitutively interacting with MAP kinase uncouples MAP kinase from p34(cdc2)/cyclin B activation in Xenopus oocytes. Molecular Biology of the Cell. 10: 2971-86. PMID 10473640 DOI: 10.1091/MBC.10.9.2971 |
0.63 |
|
| 1999 |
Ferby I, Blazquez M, Palmer A, Eritja R, Nebreda AR. A novel p34(cdc2)-binding and activating protein that is necessary and sufficient to trigger G(2)/M progression in Xenopus oocytes. Genes & Development. 13: 2177-89. PMID 10465793 DOI: 10.1101/GAD.13.16.2177 |
0.369 |
|
| 1999 |
Dorey K, Barilá D, Gavin AC, Nebreda AR, Superti-Furga G. Regulation of human c-Abl tyrosine kinase activity in Xenopus oocytes and acceleration of progesterone-induced G2/M transition by oncogenic forms. Biological Chemistry. 380: 223-30. PMID 10195429 DOI: 10.1515/BC.1999.030 |
0.607 |
|
| 1999 |
Gavin AC, Nebreda AR. A MAP kinase docking site is required for phosphorylation and activation of p90(rsk)/MAPKAP kinase-1. Current Biology : Cb. 9: 281-4. PMID 10074458 DOI: 10.1016/S0960-9822(99)80120-1 |
0.635 |
|
| 1998 |
Palmer A, Gavin AC, Nebreda AR. A link between MAP kinase and p34(cdc2)/cyclin B during oocyte maturation: p90(rsk) phosphorylates and inactivates the p34(cdc2) inhibitory kinase Myt1. The Embo Journal. 17: 5037-47. PMID 9724639 DOI: 10.1093/emboj/17.17.5037 |
0.643 |
|
| 1997 |
Reynolds CH, Nebreda AR, Gibb GM, Utton MA, Anderton BH. Reactivating kinase/p38 phosphorylates tau protein in vitro. Journal of Neurochemistry. 69: 191-8. PMID 9202310 DOI: 10.1046/j.1471-4159.1997.69010191.x |
0.449 |
|
| 1997 |
Mason C, Lake M, Nebreda A, Old R. A novel MAP kinase phosphatase is localised in the branchial arch region and tail tip of Xenopus embryos and is inducible by retinoic acid. Mechanisms of Development. 55: 133-44. PMID 8861094 DOI: 10.1016/0925-4773(96)00495-9 |
0.402 |
|
| 1996 |
Meier R, Rouse J, Cuenda A, Nebreda AR, Cohen P. Cellular Stresses and Cytokines Activate Multiple Mitogen‐Activated‐Protein Kinase Kinase Homologues in PC12 and KB Cells Febs Journal. 236: 796-805. PMID 8665897 DOI: 10.1111/J.1432-1033.1996.00796.X |
0.517 |
|
| 1996 |
Cuenda A, Alonso G, Morrice N, Jones M, Meier R, Cohen P, Nebreda AR. Purification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress- and cytokine-stimulated monocytes and epithelial cells. The Embo Journal. 15: 4156-4164. DOI: 10.1002/J.1460-2075.1996.Tb00790.X |
0.413 |
|
| 1995 |
Doza YN, Cuenda A, Thomas GM, Cohen P, Nebreda AR. Activation of the MAP kinase homologue RK requires the phosphorylation of Thr-180 and Tyr-182 and both residues are phosphorylated in chemically stressed KB cells Febs Letters. 364: 223-228. PMID 7750576 DOI: 10.1016/0014-5793(95)00346-B |
0.485 |
|
| 1995 |
Nebreda AR, Gannon JV, Hunt T. Newly synthesized protein(s) must associate with p34cdc2 to activate MAP kinase and MPF during progesterone-induced maturation of Xenopus oocytes. The Embo Journal. 14: 5597-5607. DOI: 10.1002/j.1460-2075.1995.tb00247.x |
0.47 |
|
| 1994 |
Nebreda AR. Inactivation of MAP kinases. Trends in Biochemical Sciences. 19: 1-2. PMID 8140614 DOI: 10.1016/0968-0004(94)90163-5 |
0.397 |
|
| 1994 |
Rouse J, Cohen P, Trigon S, Morange M, Alonso-Llamazares A, Zamanillo D, Hunt T, Nebreda AR. A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell. 78: 1027-1037. PMID 7923353 DOI: 10.1016/0092-8674(94)90277-1 |
0.493 |
|
| 1993 |
Merrall NW, Plevin RJ, Stokoe D, Cohen P, Nebreda AR, Gould GW. Mitogen-activated protein kinase (MAP kinase), MAP kinase kinase and c-Mos stimulate glucose transport in Xenopus oocytes. Biochemical Journal. 295: 351-355. PMID 8240233 DOI: 10.1042/Bj2950351 |
0.46 |
|
| 1993 |
Nebreda AR, Hill C, Gomez N, Cohen P, Hunt T. The protein kinase mos activates MAP kinase kinase in vitro and stimulates the MAP kinase pathway in mammalian somatic cells in vivo. Febs Letters. 333: 183-7. PMID 8224161 DOI: 10.1016/0014-5793(93)80401-F |
0.508 |
|
| 1993 |
Nebreda A, Hunt T. The c-mos proto-oncogene protein kinase turns on and maintains the activity of MAP kinase, but not MPF, in cell-free extracts of Xenopus oocytes and eggs. The Embo Journal. 12: 1979-1986. DOI: 10.1002/j.1460-2075.1993.tb05847.x |
0.489 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2008 |
Heinrichsdorff J, Luedde T, Perdiguero E, Nebreda AR, Pasparakis M. p38 alpha MAPK inhibits JNK activation and collaborates with IkappaB kinase 2 to prevent endotoxin-induced liver failure. Embo Reports. 9: 1048-54. PMID 18704119 DOI: 10.1038/embor.2008.149 |
0.298 |
|
| 2007 |
Meissner JD, Chang KC, Kubis HP, Nebreda AR, Gros G, Scheibe RJ. The p38alpha/beta mitogen-activated protein kinases mediate recruitment of CREB-binding protein to preserve fast myosin heavy chain IId/x gene activity in myotubes. The Journal of Biological Chemistry. 282: 7265-75. PMID 17210568 DOI: 10.1074/jbc.M609076200 |
0.294 |
|
| 2023 |
Gonzalez L, Domingo-Muelas A, Duart-Abadia P, Nuñez M, Mikolcevic P, Llonch E, Cubillos-Rojas M, Cánovas B, Forrow SMA, Morante-Redolat JM, Fariñas I, Nebreda AR. The atypical CDK activator RingoA/Spy1 regulates exit from quiescence in neural stem cells. Iscience. 26: 106202. PMID 36876138 DOI: 10.1016/j.isci.2023.106202 |
0.294 |
|
| 2011 |
del Barco Barrantes I, Coya JM, Maina F, Arthur JS, Nebreda AR. Genetic analysis of specific and redundant roles for p38alpha and p38beta MAPKs during mouse development. Proceedings of the National Academy of Sciences of the United States of America. 108: 12764-9. PMID 21768366 DOI: 10.1073/pnas.1015013108 |
0.289 |
|
| 2007 |
Dolado I, Swat A, Ajenjo N, De Vita G, Cuadrado A, Nebreda AR. p38alpha MAP kinase as a sensor of reactive oxygen species in tumorigenesis. Cancer Cell. 11: 191-205. PMID 17292829 DOI: 10.1016/j.ccr.2006.12.013 |
0.289 |
|
| 2023 |
Cubillos-Rojas M, Loren G, Hakim YZ, Verdaguer X, Riera A, Nebreda AR. Synthesis and Biological Activity of a VHL-Based PROTAC Specific for p38α. Cancers. 15. PMID 36765568 DOI: 10.3390/cancers15030611 |
0.288 |
|
| 2018 |
Hu P, Nebreda AR, Hanenberg H, Kinnebrew GH, Ivan M, Yoder MC, Filippi MD, Broxmeyer HE, Kapur R. P38α/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim. Nature Communications. 9: 3518. PMID 30158520 DOI: 10.1038/s41467-018-05955-2 |
0.286 |
|
| 2020 |
Arriazu E, Vicente C, Pippa R, Peris I, Martínez-Balsalobre E, García-Ramírez P, Marcotegui N, Igea A, Alignani D, Rifón J, Mateos MC, Cayuela ML, Nebreda AR, Odero MD. A new regulatory mechanism of protein phosphatase 2A activity via SET in acute myeloid leukemia. Blood Cancer Journal. 10: 3. PMID 31913266 DOI: 10.1038/s41408-019-0270-0 |
0.285 |
|
| 2017 |
Thornton TM, Hare B, Colié S, Pendlebury WW, Nebreda AR, Falls W, Jaworski DM, Rincon M. Failure to Inactivate Nuclear GSK3β by Ser(389)-Phosphorylation Leads to Focal Neuronal Death and Prolonged Fear Response. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28832021 DOI: 10.1038/npp.2017.187 |
0.285 |
|
| 2006 |
Alfonso P, Dolado I, Swat A, Núñez A, Cuadrado A, Nebreda AR, Casal JI. Proteomic analysis of p38alpha mitogen-activated protein kinase-regulated changes in membrane fractions of RAS-transformed fibroblasts. Proteomics. 6: S262-71. PMID 16534743 DOI: 10.1002/pmic.200500350 |
0.282 |
|
| 2023 |
González L, Díaz L, Pous J, Baginski B, Duran-Corbera A, Scarpa M, Brun-Heath I, Igea A, Martin-Malpartida P, Ruiz L, Pallara C, Esguerra M, Colizzi F, Mayor-Ruiz C, Biondi RM, ... ... Nebreda AR, et al. Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway. Nature Communications. 14: 3318. PMID 37308482 DOI: 10.1038/s41467-023-39051-x |
0.282 |
|
| 2011 |
Swat A, Dolado I, Igea A, Gomez-Lopez G, Pisano DG, Cuadrado A, Nebreda AR. Expression and functional validation of new p38α transcriptional targets in tumorigenesis. The Biochemical Journal. 434: 549-58. PMID 21226672 DOI: 10.1042/BJ20101410 |
0.279 |
|
| 1998 |
Gannon JV, Nebreda A, Goodger NM, Morgan PR, Hunt T. A measure of the mitotic index: studies of the abundance and half-life of p34cdc2 in cultured cells and normal and neoplastic tissues. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 3: 17-27. PMID 9581979 DOI: 10.1046/j.1365-2443.1998.00163.x |
0.275 |
|
| 2023 |
Pous J, Baginski B, Martin-Malpartida P, González L, Scarpa M, Aragon E, Ruiz L, Mees RA, Iglesias-Fernández J, Orozco M, Nebreda AR, Macias MJ. Structural basis of a redox-dependent conformational switch that regulates the stress kinase p38α. Nature Communications. 14: 7920. PMID 38040726 DOI: 10.1038/s41467-023-43763-5 |
0.272 |
|
| 2023 |
Sugioka S, Yamada H, Ishii A, Kato Y, Yamada R, Mori KP, Ohno S, Handa T, Ikushima A, Ishimura T, Osaki K, Tokudome T, Matsusaka T, Nebreda AR, Yanagita M, et al. Dual deletion of guanylyl cyclase-A and p38 mitogen-activated protein kinase in podocytes with aldosterone administration causes glomerular intra-capillary thrombi. Kidney International. PMID 37356621 DOI: 10.1016/j.kint.2023.06.007 |
0.271 |
|
| 2017 |
Trempolec N, Muñoz JP, Slobodnyuk K, Marin S, Cascante M, Zorzano A, Nebreda AR. Induction of oxidative metabolism by the p38α/MK2 pathway. Scientific Reports. 7: 11367. PMID 28900160 DOI: 10.1038/s41598-017-11309-7 |
0.266 |
|
| 2018 |
Del Barco Barrantes I, Stephan-Otto Attolini C, Slobodnyuk K, Igea A, Gregorio S, Gawrzak S, Gomis RR, Nebreda AR. Regulation of Mammary Luminal Cell Fate and Tumorigenesis by p38α. Stem Cell Reports. 10: 257-271. PMID 29290625 DOI: 10.1016/j.stemcr.2017.11.021 |
0.26 |
|
| 2008 |
Jagemann LR, Pérez-Rivas LG, Ruiz EJ, Ranea JA, Sánchez-Jiménez F, Nebreda AR, Alba E, Lozano J. The functional interaction of 14-3-3 proteins with the ERK1/2 scaffold KSR1 occurs in an isoform-specific manner. The Journal of Biological Chemistry. 283: 17450-62. PMID 18426801 DOI: 10.1074/jbc.M709185200 |
0.257 |
|
| 1992 |
Porras A, Nebreda A, Benito M, Santos E. Activation of Ras by insulin in 3T3 L1 cells does not involve GTPase-activating protein phosphorylation. Journal of Biological Chemistry. 267: 21124-21131. DOI: 10.1016/s0021-9258(19)36806-1 |
0.257 |
|
| 2002 |
Terret ME, Ferby I, Nebreda AR, Verlhac MH. RINGO efficiently triggers meiosis resumption in mouse oocytes and induces cell cycle arrest in embryos. Biology of the Cell. 93: 89-97. PMID 11730327 DOI: 10.1016/S0248-4900(01)01122-4 |
0.255 |
|
| 2008 |
Dolado I, Nebreda AR. AKT and oxidative stress team up to kill cancer cells. Cancer Cell. 14: 427-9. PMID 19061832 DOI: 10.1016/j.ccr.2008.11.006 |
0.248 |
|
| 2015 |
Gupta J, Igea A, Papaioannou M, Lopez-Casas PP, Llonch E, Hidalgo M, Gorgoulis VG, Nebreda AR. Pharmacological inhibition of p38 MAPK reduces tumor growth in patient-derived xenografts from colon tumors. Oncotarget. 6: 8539-51. PMID 25890501 DOI: 10.18632/oncotarget.3816 |
0.246 |
|
| 2020 |
Donoghue C, Cubillos-Rojas M, Gutierrez-Prat N, Sanchez-Zarzalejo C, Verdaguer X, Riera A, Nebreda AR. Optimal linker length for small molecule PROTACs that selectively target p38α and p38β for degradation. European Journal of Medicinal Chemistry. 201: 112451. PMID 32634680 DOI: 10.1016/J.Ejmech.2020.112451 |
0.245 |
|
| 2018 |
Youssif C, Cubillos-Rojas M, Comalada M, Llonch E, Perna C, Djouder N, Nebreda AR. Myeloid p38α signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis. Embo Molecular Medicine. 10. PMID 29907597 DOI: 10.15252/emmm.201708403 |
0.242 |
|
| 2012 |
Hu P, Carlesso N, Xu M, Liu Y, Nebreda AR, Takemoto C, Kapur R. Genetic evidence for critical roles of P38α protein in regulating mast cell differentiation and chemotaxis through distinct mechanisms. The Journal of Biological Chemistry. 287: 20258-69. PMID 22518842 DOI: 10.1074/Jbc.M112.358119 |
0.241 |
|
| 1991 |
Nebreda AR, Martin-Zanca D, Kaplan DR, Parada LF, Santos E. Induction by NGF of meiotic maturation of Xenopus oocytes expressing the trk proto-oncogene product. Science (New York, N.Y.). 252: 558-61. PMID 1850550 |
0.24 |
|
| 2009 |
Cuadrado M, Gutierrez-Martinez P, Swat A, Nebreda AR, Fernandez-Capetillo O. p27Kip1 stabilization is essential for the maintenance of cell cycle arrest in response to DNA damage. Cancer Research. 69: 8726-32. PMID 19843869 DOI: 10.1158/0008-5472.Can-09-0729 |
0.238 |
|
| 2010 |
Santamaria PG, Nebreda AR. Deconstructing ERK signaling in tumorigenesis. Molecular Cell. 38: 3-5. PMID 20385084 DOI: 10.1016/j.molcel.2010.03.012 |
0.238 |
|
| 2013 |
Amata I, Maffei M, Igea A, Gay M, Vilaseca M, Nebreda AR, Pons M. Cover Picture: Multi-phosphorylation of the Intrinsically Disordered Unique Domain of c-Src Studied by In-Cell and Real-Time NMR Spectroscopy (ChemBioChem 14/2013) Chembiochem. 14: 1669-1669. DOI: 10.1002/CBIC.201390050 |
0.237 |
|
| 2013 |
Pérez Y, Maffei M, Igea A, Amata I, Gairí M, Nebreda AR, Bernadó P, Pons M. Lipid binding by the Unique and SH3 domains of c-Src suggests a new regulatory mechanism. Scientific Reports. 3: 1295. PMID 23416516 DOI: 10.1038/Srep01295 |
0.235 |
|
| 2016 |
Isoda M, Mikolcevic P, Nebreda AR. New insights into Cdk2 regulation during meiosis. Cell Cycle (Georgetown, Tex.). 15: 2681-2. PMID 27384249 DOI: 10.1080/15384101.2016.1204856 |
0.234 |
|
| 2019 |
Martín-Segura A, Casadomé-Perales Á, Fazzari P, Mas JM, Artigas L, Valls R, Nebreda AR, Dotti CG. Aging Increases Hippocampal DUSP2 by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism. Frontiers in Neurology. 10: 675. PMID 31293510 DOI: 10.3389/Fneur.2019.00675 |
0.232 |
|
| 2002 |
Schmitt A, Nebreda AR. Signalling pathways in oocyte meiotic maturation. Journal of Cell Science. 115: 2457-9. PMID 12045215 DOI: 10.1242/jcs.115.12.2457 |
0.226 |
|
| 2007 |
Ventura JJ, Tenbaum S, Perdiguero E, Huth M, Guerra C, Barbacid M, Pasparakis M, Nebreda AR. p38alpha MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation. Nature Genetics. 39: 750-8. PMID 17468755 DOI: 10.1038/Ng2037 |
0.226 |
|
| 2010 |
Cuadrado A, Corrado N, Perdiguero E, Lafarga V, Muñoz-Canoves P, Nebreda AR. Essential role of p18Hamlet/SRCAP-mediated histone H2A.Z chromatin incorporation in muscle differentiation. The Embo Journal. 29: 2014-25. PMID 20473270 DOI: 10.1038/emboj.2010.85 |
0.226 |
|
| 2004 |
Perdiguero E, Nebreda AR. Use of Xenopus oocytes and early embryos to study MAPK signaling. Methods in Molecular Biology (Clifton, N.J.). 250: 299-314. PMID 14755096 DOI: 10.1385/1-59259-671-1:299 |
0.218 |
|
| 2013 |
Tormos AM, Arduini A, Talens-Visconti R, del Barco Barrantes I, Nebreda AR, Sastre J. Liver-specific p38α deficiency causes reduced cell growth and cytokinesis failure during chronic biliary cirrhosis in mice. Hepatology (Baltimore, Md.). 57: 1950-61. PMID 23354775 DOI: 10.1002/hep.26174 |
0.204 |
|
| 2002 |
Perez LH, Antonio C, Flament S, Vernos I, Nebreda AR. Xkid chromokinesin is required for the meiosis I to meiosis II transition in Xenopus laevis oocytes. Nature Cell Biology. 4: 737-42. PMID 12360284 DOI: 10.1038/ncb850 |
0.2 |
|
| 2009 |
Cuenda A, Nebreda AR. p38delta and PKD1: kinase switches for insulin secretion. Cell. 136: 209-10. PMID 19167323 DOI: 10.1016/j.cell.2009.01.005 |
0.2 |
|
| 2014 |
Urosevic J, Garcia-Albéniz X, Planet E, Real S, Céspedes MV, Guiu M, Fernandez E, Bellmunt A, Gawrzak S, Pavlovic M, Mangues R, Dolado I, Barriga FM, Nadal C, Kemeny N, ... ... Nebreda AR, et al. Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling and PTHLH. Nature Cell Biology. 16: 685-94. PMID 24880666 DOI: 10.1038/ncb2977 |
0.194 |
|
| 1989 |
Santos E, Nebreda AR. Structural and functional properties of ras proteins. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 3: 2151-63. PMID 2666231 DOI: 10.1096/fasebj.3.10.2666231 |
0.194 |
|
| 2012 |
Barry AO, Boucherit N, Mottola G, Vadovic P, Trouplin V, Soubeyran P, Capo C, Bonatti S, Nebreda A, Toman R, Lemichez E, Mege JL, Ghigo E. Impaired stimulation of p38α-MAPK/Vps41-HOPS by LPS from pathogenic Coxiella burnetii prevents trafficking to microbicidal phagolysosomes. Cell Host & Microbe. 12: 751-63. PMID 23245320 DOI: 10.1016/J.Chom.2012.10.015 |
0.188 |
|
| 2019 |
Rius-Pérez S, Tormos AM, Pérez S, Finamor I, Rada P, Valverde ÁM, Nebreda AR, Sastre J, Taléns-Visconti R. p38α deficiency restrains liver regeneration after partial hepatectomy triggering oxidative stress and liver injury. Scientific Reports. 9: 3775. PMID 30846722 DOI: 10.1038/s41598-019-39428-3 |
0.183 |
|
| 2018 |
Curtis M, Kenny HA, Ashcroft B, Mukherjee A, Johnson A, Zhang Y, Helou Y, Batlle R, Liu X, Gutierrez N, Gao X, Yamada SD, Lastra R, Montag A, Ahsan N, ... ... Nebreda AR, et al. Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis. Cell Metabolism. PMID 30174305 DOI: 10.1016/J.Cmet.2018.08.007 |
0.182 |
|
| 2016 |
Clemente-Ruiz M, Murillo-Maldonado JM, Benhra N, Barrio L, Pérez L, Quiroga G, Nebreda AR, Milán M. Gene Dosage Imbalance Contributes to Chromosomal Instability-Induced Tumorigenesis. Developmental Cell. 36: 290-302. PMID 26859353 DOI: 10.1016/j.devcel.2016.01.008 |
0.18 |
|
| 2004 |
Perdiguero E, Nebreda AR. Regulation of Cdc25C Activity During the Meiotic G2/M Transition Cell Cycle. 3: 731-735. DOI: 10.4161/cc.3.6.906 |
0.177 |
|
| 2012 |
Hu P, Nebreda AR, Liu Y, Carlesso N, Kaplan M, Kapur R. p38α protein negatively regulates T helper type 2 responses by orchestrating multiple T cell receptor-associated signals. The Journal of Biological Chemistry. 287: 33215-26. PMID 22859305 DOI: 10.1074/Jbc.M112.355594 |
0.176 |
|
| 2020 |
Vitos-Faleato J, Real SM, Gutierrez-Prat N, Villanueva A, Llonch E, Drosten M, Barbacid M, Nebreda AR. Requirement for epithelial p38α in KRAS-driven lung tumor progression. Proceedings of the National Academy of Sciences of the United States of America. PMID 31969449 DOI: 10.1073/Pnas.1921404117 |
0.173 |
|
| 2018 |
De Mol E, Szulc E, Di Sanza C, Martínez-Cristóbal P, Bertoncini CW, Fenwick RB, Frigolé-Vivas M, Masín M, Hunter I, Buzón V, Brun-Heath I, García J, De Fabritiis G, Estébanez-Perpiñá E, McEwan IJ, et al. Regulation of Androgen Receptor Activity by Transient Interactions of Its Transactivation Domain with General Transcription Regulators. Structure (London, England : 1993). 26: 145-152.e3. PMID 29225078 DOI: 10.1016/j.str.2017.11.007 |
0.164 |
|
| 2019 |
Batlle R, Andrés E, Gonzalez L, Llonch E, Igea A, Gutierrez-Prat N, Berenguer-Llergo A, Nebreda AR. Regulation of tumor angiogenesis and mesenchymal-endothelial transition by p38α through TGF-β and JNK signaling. Nature Communications. 10: 3071. PMID 31296856 DOI: 10.1038/s41467-019-10946-y |
0.164 |
|
| 2020 |
Urosevic J, Blasco MT, Llorente A, Bellmunt A, Berenguer-Llergo A, Guiu M, Cañellas A, Fernandez E, Burkov I, Clapés Cabrer M, Cartañá M, Figueras-Puig C, Batlle E, Nebreda AR, Gomis RR. ERK1/2 signaling induces upregulation of ANGPT2 and CXCR4 to mediate liver metastasis in colon cancer. Cancer Research. PMID 32816905 DOI: 10.1158/0008-5472.CAN-19-4028 |
0.163 |
|
| 2018 |
Pérez S, Rius-Pérez S, Tormos AM, Finamor I, Nebreda ÁR, Taléns-Visconti R, Sastre J. Age-dependent regulation of antioxidant genes by p38α MAPK in the liver. Redox Biology. 16: 276-284. PMID 29567616 DOI: 10.1016/j.redox.2018.02.017 |
0.161 |
|
| 1991 |
Nebreda AR, Bryan T, Segade F, Wingfield P, Venkatesan S, Santos E. Biochemical and biological comparison of HIV-1 NEF and ras gene products. Virology. 183: 151-9. PMID 2053279 DOI: 10.1016/0042-6822(91)90128-X |
0.161 |
|
| 1991 |
Benito M, Porras A, Nebreda AR, Santos E. Differentiation of 3T3-L1 fibroblasts to adipocytes induced by transfection of ras oncogenes. Science (New York, N.Y.). 253: 565-8. PMID 1857988 DOI: 10.1126/SCIENCE.1857988 |
0.153 |
|
| 2020 |
Marruecos L, Bertran J, Guillén Y, González J, Batlle R, López-Arribillaga E, Garrido M, Ruiz-Herguido C, Lisiero D, González-Farré M, Arce-Gallego S, Iglesias M, Nebreda AR, Miyamoto S, Bigas A, et al. IκBα deficiency imposes a fetal phenotype to intestinal stem cells. Embo Reports. e49708. PMID 32270911 DOI: 10.15252/Embr.201949708 |
0.151 |
|
| 2018 |
Matesanz N, Nikolic I, Leiva M, Pulgarín-Alfaro M, Santamans AM, Bernardo E, Mora A, Herrera-Melle L, Rodríguez E, Beiroa D, Caballero A, Martín-García E, Acín-Pérez R, Hernández-Cosido L, Leiva-Vega L, ... ... Nebreda AR, et al. p38α blocks brown adipose tissue thermogenesis through p38δ inhibition. Plos Biology. 16: e2004455. PMID 29979672 DOI: 10.1371/journal.pbio.2004455 |
0.15 |
|
| 2017 |
Tormos AM, Rius-Pérez S, Jorques M, Rada P, Ramirez L, Valverde ÁM, Nebreda ÁR, Sastre J, Taléns-Visconti R. p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging. Plos One. 12: e0171738. PMID 28166285 DOI: 10.1371/journal.pone.0171738 |
0.147 |
|
| 2019 |
Ivanova S, Polajnar M, Narbona-Perez AJ, Hernandez-Alvarez MI, Frager P, Slobodnyuk K, Plana N, Nebreda AR, Palacin M, Gomis RR, Behrends C, Zorzano A. Regulation of death receptor signaling by the autophagy protein TP53INP2. The Embo Journal. 38. PMID 30979779 DOI: 10.15252/embj.201899300 |
0.146 |
|
| 2018 |
Cánovas B, Igea A, Sartori AA, Gomis RR, Paull TT, Isoda M, Pérez-Montoyo H, Serra V, González-Suárez E, Stracker TH, Nebreda AR. Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells. Cancer Cell. PMID 29805078 DOI: 10.1016/J.Ccell.2018.04.010 |
0.146 |
|
| 2021 |
Nebreda AR, Barral Y. Demixing the cell: how cells channel and store signaling information. Current Opinion in Cell Biology. 69: iii-v. PMID 33789797 DOI: 10.1016/j.ceb.2021.02.012 |
0.145 |
|
| 2014 |
Tormos AM, Pérez-Garrido S, Taléns-Visconti R, Nebreda ÁR, Sastre J. Long term p38-a deficiency up-regulates antioxidant enzymes through compensatory NF-?B activation. Free Radical Biology & Medicine. 75: S52. PMID 26461407 DOI: 10.1016/j.freeradbiomed.2014.10.823 |
0.144 |
|
| 2014 |
Urosevic J, Nebreda AR, Gomis RR. MAPK signaling control of colon cancer metastasis. Cell Cycle (Georgetown, Tex.). 13: 2641-2. PMID 25486343 DOI: 10.4161/15384101.2014.946374 |
0.142 |
|
| 1991 |
Daar I, Nebreda AR, Yew N, Sass P, Paules R, Santos E, Wigler M, Vande Woude GF. The ras oncoprotein and M-phase activity. Science (New York, N.Y.). 253: 74-6. PMID 1829549 DOI: 10.1126/Science.1829549 |
0.142 |
|
| 2014 |
Gupta J, delBarcoBarrantes I, Igea A, Sakellariou S, Pateras IS, Gorgoulis VG, Nebreda AR. Dual Function of p38α MAPK in Colon Cancer: Suppression of Colitis-Associated Tumor Initiation but Requirement for Cancer Cell Survival Cancer Cell. 25: 484-500. PMID 24684847 DOI: 10.1016/j.ccr.2014.02.019 |
0.14 |
|
| 1984 |
Esteban R, Nebreda AR. Synthesis and Regulation of Bacillus circulans WL-12 1,3- -D-Glucanases Microbiology. 130: 2483-2487. DOI: 10.1099/00221287-130-10-2483 |
0.13 |
|
| 2019 |
Eftekharzadeh B, Banduseela VC, Chiesa G, Martínez-Cristóbal P, Rauch JN, Nath SR, Schwarz DMC, Shao H, Marin-Argany M, Di Sanza C, Giorgetti E, Yu Z, Pieratelli R, Felli IC, Brun-Heath I, et al. Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor. Nature Communications. 10: 3562. PMID 31395886 DOI: 10.1038/S41467-019-11594-Y |
0.126 |
|
| 1991 |
Vazquez de Aldana CR, Correa J, San Segundo P, Bueno A, Nebreda AR, Mendez E, del Rey F. Nucleotide sequence of the exo-1,3-beta-glucanase-encoding gene, EXG1, of the yeast Saccharomyces cerevisiae. Gene. 97: 173-82. PMID 1900250 DOI: 10.1016/0378-1119(91)90049-H |
0.119 |
|
| 2019 |
Eftekharzadeh B, Banduseela VC, Chiesa G, Martínez-Cristóbal P, Rauch JN, Nath SR, Schwarz DMC, Shao H, Marin-Argany M, Di Sanza C, Giorgetti E, Yu Z, Pierattelli R, Felli IC, Brun-Heath I, et al. Author Correction: Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor. Nature Communications. 10: 4605. PMID 31591399 DOI: 10.1038/S41467-019-12578-8 |
0.118 |
|
| 1992 |
Daar I, Zhou R, Shen RL, Nebreda A, Oskarsson M, Santos E, da Silva PP, Masui Y, Vande Woude GF. Mos and Ras: two oncoproteins that display M-phase activity. Cold Spring Harbor Symposia On Quantitative Biology. 56: 477-88. PMID 1840260 DOI: 10.1101/SQB.1991.056.01.054 |
0.117 |
|
| 2017 |
Perez S, Rius-Perez S, Finamor I, Martinez A, Marti P, Nebreda A, Talens R, Sastre J. p38α and NF-κB regulate antioxidant defense in the liver through an age-dependent mechanism Free Radical Biology and Medicine. 108: S47. DOI: 10.1016/J.FREERADBIOMED.2017.04.173 |
0.111 |
|
| 1984 |
Esteban R, Nebreda A, Villanueva J, Villa* T. Possible role of cAMP in the synthesis of β-glucanases and β-xylanases ofBacillus circulansWL-12 Fems Microbiology Letters. 23: 91-94. DOI: 10.1111/J.1574-6968.1984.TB01041.X |
0.109 |
|
| 1987 |
Nebreda AR, Villa TG, Villanueva JR, del Rey F. Cloning of genes related to exo-beta-glucanase production in Saccharomyces cerevisiae: characterization of an exo-beta-glucanase structural gene. Gene. 47: 245-59. PMID 3104142 DOI: 10.1016/0378-1119(86)90068-5 |
0.102 |
|
| 2016 |
Jaeger S, Igea A, Arroyo R, Alcalde V, Canovas B, Orozco M, Nebreda AR, Aloy P. Quantification of pathway crosstalk reveals novel synergistic drug combinations for breast cancer. Cancer Research. PMID 27879272 DOI: 10.1158/0008-5472.Can-16-0097 |
0.102 |
|
| 2018 |
Tauriello DVF, Palomo-Ponce S, Stork D, Berenguer-Llergo A, Badia-Ramentol J, Iglesias M, Sevillano M, Ibiza S, Cañellas A, Hernando-Momblona X, Byrom D, Matarin JA, Calon A, Rivas EI, Nebreda AR, et al. TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis. Nature. PMID 29443964 DOI: 10.1038/Nature25492 |
0.1 |
|
| 2001 |
Kimura Y, Schmitt A, Fukushima N, Ishii I, Kimura H, Nebreda AR, Chun J. Two novel Xenopus homologs of mammalian LP(A1)/EDG-2 function as lysophosphatidic acid receptors in Xenopus oocytes and mammalian cells. The Journal of Biological Chemistry. 276: 15208-15. PMID 11278944 DOI: 10.1074/Jbc.M011588200 |
0.096 |
|
| 1984 |
Sánchez A, Nebreda AR, Villanueva JR, Villa TG. Post-secretional modification of exo-1,3-beta-D-glucanases from Saccharomyces cerevisiae. The Biochemical Journal. 215: 471-4. PMID 6419724 DOI: 10.1042/BJ2150471 |
0.096 |
|
| 2019 |
Moreno‐Cugnon L, Revuelta M, Arrizabalaga O, Colie S, Moreno‐Valladares M, Jimenez‐Blasco D, Gil‐Bea F, Llarena I, Bolaños JP, Nebreda AR, Matheu A. Neuronal p38α mediates age-associated neural stem cell exhaustion and cognitive decline. Aging Cell. 18. PMID 31560167 DOI: 10.1111/Acel.13044 |
0.095 |
|
| 2018 |
Gawrzak S, Rinaldi L, Gregorio S, Arenas EJ, Salvador F, Urosevic J, Figueras-Puig C, Rojo F, Del Barco Barrantes I, Cejalvo JM, Palafox M, Guiu M, Berenguer-Llergo A, Symeonidi A, Bellmunt A, ... ... Nebreda AR, et al. MSK1 regulates luminal cell differentiation and metastatic dormancy in ER+ breast cancer. Nature Cell Biology. PMID 29358704 DOI: 10.1038/s41556-017-0021-z |
0.092 |
|
| 2019 |
Navarrete M, Cuartero MI, Palenzuela R, Draffin JE, Konomi A, Serra I, Colié S, Castaño-Castaño S, Hasan MT, Nebreda ÁR, Esteban JA. Astrocytic p38α MAPK drives NMDA receptor-dependent long-term depression and modulates long-term memory. Nature Communications. 10: 2968. PMID 31273206 DOI: 10.1038/s41467-019-10830-9 |
0.089 |
|
| 2017 |
Colié S, Sarroca S, Palenzuela R, Garcia I, Matheu A, Corpas R, Dotti CG, Esteban JA, Sanfeliu C, Nebreda AR. Neuronal p38α mediates synaptic and cognitive dysfunction in an Alzheimer's mouse model by controlling β-amyloid production. Scientific Reports. 7: 45306. PMID 28361984 DOI: 10.1038/Srep45306 |
0.082 |
|
| 1992 |
Nebreda AR, Segade F, Santos E. The nef gene products: biochemical properties and effects on host cell functions. Research in Virology. 143: 55-9. PMID 1565859 DOI: 10.1016/S0923-2516(06)80081-6 |
0.078 |
|
| 2018 |
Gawrzak S, Rinaldi L, Gregorio S, Arenas EJ, Salvador F, Urosevic J, Figueras-Puig C, Rojo F, Del Barco Barrantes I, Cejalvo JM, Palafox M, Guiu M, Berenguer-Llergo A, Symeonidi A, Bellmunt A, ... ... Nebreda AR, et al. Publisher Correction: MSK1 regulates luminal cell differentiation and metastatic dormancy in ER breast cancer. Nature Cell Biology. PMID 29674681 DOI: 10.1038/s41556-018-0052-0 |
0.075 |
|
| 1987 |
Nebreda AR, Vazquez CR, Villa TG, Villanueva JR, del Rey F. Heterogeneous glycosylation of the EXG1 gene product accounts for the two extracellular exo-beta-glucanases of Saccharomyces cerevisiae. Febs Letters. 220: 27-30. PMID 3111887 DOI: 10.1016/0014-5793(87)80869-4 |
0.069 |
|
| 2022 |
Suñer C, Sibilio A, Martín J, Castellazzi CL, Reina O, Dotu I, Caballé A, Rivas E, Calderone V, Díez J, Nebreda AR, Méndez R. Macrophage inflammation resolution requires CPEB4-directed offsetting of mRNA degradation. Elife. 11. PMID 35442882 DOI: 10.7554/eLife.75873 |
0.068 |
|
| 2000 |
Antonio C, Ferby I, Wilhelm H, Jones M, Karsenti E, Nebreda AR, Vernos I. Xkid, a chromokinesin required for chromosome alignment on the metaphase plate. Cell. 102: 425-35. PMID 10966105 DOI: 10.1016/S0092-8674(00)00048-9 |
0.057 |
|
| 2015 |
Igea A, Gupta J, Nebreda AR. Targeting of non-oncogene addiction. Aging. 7: 525-6. PMID 26298432 DOI: 10.18632/aging.100796 |
0.046 |
|
| 1982 |
Sánchez A, Nebreda AR, Villa TG. Self-associating properties of yeast exo-beta-glucanases are dependent on the ionic strength. Febs Letters. 145: 213-6. PMID 6751872 DOI: 10.1016/0014-5793(82)80170-1 |
0.045 |
|
| 2016 |
García-Mesa Y, Colie S, Corpas R, Cristòfol R, Comellas F, Nebreda AR, Giménez-Llort L, Sanfeliu C. Oxidative Stress Is a Central Target for Physical Exercise Neuroprotection Against Pathological Brain Aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 71: 40-9. PMID 25720862 DOI: 10.1093/gerona/glv005 |
0.036 |
|
| 2017 |
Gómez-Miragaya J, Palafox M, Paré L, Yoldi G, Ferrer I, Vila S, Galván P, Pellegrini P, Pérez-Montoyo H, Igea A, Muñoz P, Esteller M, Nebreda AR, Urruticoechea A, Morilla I, et al. Resistance to Taxanes in Triple-Negative Breast Cancer Associates with the Dynamics of a CD49f+ Tumor-Initiating Population. Stem Cell Reports. PMID 28457887 DOI: 10.1016/J.Stemcr.2017.03.026 |
0.026 |
|
| 2014 |
Gupta J, Nebreda A. Induction of Colitis and Colitis-associated Colorectal Cancer (CAC) Bio-Protocol. 4. DOI: 10.21769/BIOPROTOC.1290 |
0.021 |
|
| 2021 |
Gaestel M, Nebreda AR, Yaffe MB. Cytokine Storm. The New England Journal of Medicine. 384: e59. PMID 33882214 DOI: 10.1056/NEJMc2036236#sa1 |
0.01 |
|
| 2014 |
Gupta J, Nebreda A. Analysis of Intestinal Permeability in Mice Bio-Protocol. 4. DOI: 10.21769/BIOPROTOC.1289 |
0.01 |
|
| 2009 |
Nebreda A. Angel Nebreda. Febs Letters. 583: 2155-6. PMID 19508872 DOI: 10.1016/j.febslet.2009.06.005 |
0.01 |
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