MARK BOYETT - Publications

Affiliations: 
University of Leeds, Leeds, England, United Kingdom 

133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Bai X, Wang K, Boyett MR, Hancox JC, Zhang H. The Functional Role of Hyperpolarization Activated Current ( ) on Cardiac Pacemaking in Human vs. in the Rabbit Sinoatrial Node: A Simulation and Theoretical Study. Frontiers in Physiology. 12: 582037. PMID 34489716 DOI: 10.3389/fphys.2021.582037  0.514
2021 Boyett MR, Yanni J, Tellez J, Bucchi A, Mesirca P, Cai X, Logantha SJRJ, Wilson C, Anderson C, Ariyaratnam J, Stuart L, Nakao S, Abd Allah E, Jones S, Lancaster M, et al. Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease. Progress in Biophysics and Molecular Biology. PMID 34197836 DOI: 10.1016/j.pbiomolbio.2021.06.008  0.566
2021 Logantha SJRJ, Cai XJ, Yanni J, Jones CB, Stephenson RS, Stuart L, Quigley G, Monfredi O, Nakao S, Oh IY, Starborg T, Kitmitto A, Vohra A, Hutcheon RC, Corno AF, ... ... Boyett MR, et al. Remodeling of the Purkinje Network in Congestive Heart Failure in the Rabbit. Circulation. Heart Failure. CIRCHEARTFAILURE1200. PMID 34190577 DOI: 10.1161/CIRCHEARTFAILURE.120.007505  0.486
2021 Mesirca P, Nakao S, Nissen SD, Forte G, Anderson C, Trussell T, Li J, Cox C, Zi M, Logantha SJR, Yaar S, Carstensen H, Bidaud I, Stuart L, Soattin L, ... ... Boyett MR, et al. Intrinsic Electrical Remodeling Underlies Atrioventricular Block in Athletes. Circulation Research. PMID 33849278 DOI: 10.1161/CIRCRESAHA.119.316386  0.531
2021 Wang Y, Anderson C, Dobrzynski H, Hart G, D'Souza A, Boyett MR. RNAseq shows an all-pervasive day-night rhythm in the transcriptome of the pacemaker of the heart. Scientific Reports. 11: 3565. PMID 33574422 DOI: 10.1038/s41598-021-82202-7  0.502
2020 Bidaud I, D'Souza A, Forte G, Torre E, Greuet D, Thirard S, Anderson C, Chung You Chong A, Torrente AG, Roussel J, Wickman K, Boyett MR, Mangoni ME, Mesirca P. Genetic Ablation of G Protein-Gated Inwardly Rectifying K Channels Prevents Training-Induced Sinus Bradycardia. Frontiers in Physiology. 11: 519382. PMID 33551824 DOI: 10.3389/fphys.2020.519382  0.466
2020 Alghamdi AM, Boyett MR, Hancox JC, Zhang H. Cardiac Pacemaker Dysfunction Arising From Different Studies of Ion Channel Remodeling in the Aging Rat Heart. Frontiers in Physiology. 11: 546508. PMID 33343378 DOI: 10.3389/fphys.2020.546508  0.516
2020 Alghamdi AM, Testrow CP, Whittaker DG, Boyett MR, Hancox JC, Zhang H. Mechanistic Insights Into the Reduced Pacemaking Rate of the Rabbit Sinoatrial Node During Postnatal Development: A Simulation Study. Frontiers in Physiology. 11: 547577. PMID 33329016 DOI: 10.3389/fphys.2020.547577  0.552
2020 D'Souza A, Wang Y, Anderson C, Bucchi A, Barsucotti M, Olieslagers S, Mesirca P, Johnsen AB, Mastitskaya S, Ni H, Zhang Y, Black N, Cox C, Wegner S, Bano-Otalora B, ... ... Boyett MR, et al. A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate. Heart Rhythm. PMID 33278629 DOI: 10.1016/j.hrthm.2020.11.026  0.526
2020 Yanni J, D'Souza A, Wang Y, Li N, Hansen BJ, Zakharkin SO, Smith M, Hayward C, Whitson BA, Mohler PJ, Janssen PML, Zeef L, Choudhury M, Zi M, Cai X, ... ... Boyett MR, et al. Silencing miR-370-3p rescues funny current and sinus node function in heart failure. Scientific Reports. 10: 11279. PMID 32647133 DOI: 10.1038/S41598-020-67790-0  0.521
2020 Boyett M, Lundby A. A New Window onto the Pacemaker of the Heart, the Sinus Node, Provided by Quantitative Proteomics and Single-Nucleus Transcriptomics. Journal of Cellular Immunology. 2: 38-41. PMID 32342062  0.541
2019 Logantha SJRJ, Kharche SR, Zhang Y, Atkinson AJ, Hao G, Boyett MR, Dobrzynski H. Sinus node-like pacemaker mechanisms regulate ectopic pacemaker activity in the adult rat atrioventricular ring. Scientific Reports. 9: 11781. PMID 31409881 DOI: 10.1038/s41598-019-48276-0  0.56
2019 D'Souza A, Trussell T, Morris GM, Dobrzynski H, Boyett MR. Supraventricular Arrhythmias in Athletes: Basic Mechanisms and New Directions. Physiology (Bethesda, Md.). 34: 314-326. PMID 31389775 DOI: 10.1152/physiol.00009.2019  0.538
2019 Zhang Y, Wang Y, Yanni J, Qureshi MA, Logantha SJRJ, Kassab S, Boyett MR, Gardiner NJ, Sun H, Howarth FC, Dobrzynski H. Electrical Conduction System Remodeling in Streptozotocin-Induced Diabetes Mellitus Rat Heart. Frontiers in Physiology. 10: 826. PMID 31338036 DOI: 10.3389/Fphys.2019.00826  0.473
2019 Linscheid N, Logantha SJRJ, Poulsen PC, Zhang S, Schrölkamp M, Egerod KL, Thompson JJ, Kitmitto A, Galli G, Humphries MJ, Zhang H, Pers TH, Olsen JV, Boyett M, Lundby A. Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking. Nature Communications. 10: 2889. PMID 31253831 DOI: 10.1038/S41467-019-10709-9  0.582
2019 Boyett M, Wang Y, D'Souza A. CrossTalk opposing view: Heart rate variability as a measure of cardiac autonomic responsiveness is fundamentally flawed. The Journal of Physiology. PMID 31006856 DOI: 10.1113/Jp277501  0.496
2019 Boyett M, Wang Y, D'Souza A. Rebuttal from Mark Boyett, Yanwen Wang and Alicia D'Souza. The Journal of Physiology. PMID 31006854 DOI: 10.1113/Jp277963  0.37
2019 Orini M, Yanni J, Taggart P, Hanson B, Hayward M, Smith A, Zhang H, Colman M, Jones G, Jie X, Dobrzynski H, Boyett MR, Lambiase PD. Mechanistic insights from targeted molecular profiling of repolarization alternans in the intact human heart. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. PMID 30753421 DOI: 10.1093/Europace/Euz007  0.537
2018 Wang W, Zhang S, Ni H, Garratt CJ, Boyett MR, Hancox JC, Zhang H. Mechanistic insight into spontaneous transition from cellular alternans to arrhythmia-A simulation study. Plos Computational Biology. 14: e1006594. PMID 30500818 DOI: 10.1371/Journal.Pcbi.1006594  0.548
2018 Black N, D'Souza A, Wang Y, Piggins H, Dobrzynski H, Morris G, Boyett MR. Circadian rhythm of cardiac electrophysiology, arrhythmogenesis and the underlying mechanisms. Heart Rhythm. PMID 30170229 DOI: 10.1016/J.Hrthm.2018.08.026  0.544
2017 Bai X, Wang K, Yuan Y, Li Q, Dobrzynski H, Boyett MR, Hancox JC, Zhang H. Mechanism underlying impaired cardiac pacemaking rhythm during ischemia: A simulation study. Chaos (Woodbury, N.Y.). 27: 093934. PMID 28964153 DOI: 10.1063/1.5002664  0.576
2017 Boyett MR. Last Word on Point:Counterpoint. Journal of Applied Physiology (Bethesda, Md. : 1985). 123: 694. PMID 28947628 DOI: 10.1152/japplphysiol.00542.2017  0.358
2017 D'Souza A, Pearman CM, Wang Y, Nakao S, Logantha SJR, Cox C, Bennett HJ, Zhang Y, Johnsen AB, Linscheid N, Poulsen PC, Elliott J, Coulson J, McPhee JS, Robertson AC, ... ... Boyett MR, et al. Targeting miR-423-5p Reverses Exercise Training-Induced HCN4 Channel Remodeling and Sinus Bradycardia. Circulation Research. PMID 28821541 DOI: 10.1161/Circresaha.117.311607  0.44
2017 Boyett MR, Wang Y, Nakao S, Ariyaratnam J, Hart G, Monfredi O, D'Souza A. Rebuttal from Boyett. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.00606.2017. PMID 28684595 DOI: 10.1152/Japplphysiol.00606.2017  0.356
2017 Boyett MR, Wang Y, Nakao S, Ariyaratnam J, Hart G, Monfredi O, D'Souza A. Point: Exercise training-induced bradycardia is caused by changes in intrinsic sinus node function. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.00604.2017. PMID 28684593 DOI: 10.1152/Japplphysiol.00604.2017  0.445
2017 Wang Y, Wang S, Lei M, Boyett M, Tsui H, Liu W, Wang X. The Pak1 signalling pathway in cardiac disease: from mechanistic study to therapeutic exploration. British Journal of Pharmacology. PMID 28574147 DOI: 10.1111/Bph.13872  0.498
2017 Pinali C, Malik N, Davenport JB, Allan LJ, Murfitt L, Iqbal MM, Boyett MR, Wright EJ, Walker R, Zhang Y, Dobryznski H, Holt CM, Kitmitto A. Post-Myocardial Infarction T-tubules Form Enlarged Branched Structures With Dysregulation of Junctophilin-2 and Bridging Integrator 1 (BIN-1). Journal of the American Heart Association. 6. PMID 28473402 DOI: 10.1161/JAHA.116.004834  0.436
2016 Temple IP, Logantha SJ, Absi M, Zhang Y, Pervolaraki E, Yanni J, Atkinson A, Petkova M, Quigley GM, Castro S, Drinkhill M, Schneider H, Monfredi O, Cartwright E, Zi M, ... ... Boyett MR, et al. Atrioventricular Node Dysfunction and Ion Channel Transcriptome in Pulmonary Hypertension. Circulation. Arrhythmia and Electrophysiology. 9. PMID 27979911 DOI: 10.1161/Circep.115.003432  0.543
2016 Chowdhury SK, Liu W, Zi M, Li Y, Wang S, Tsui H, Prehar S, Castro SJ, Zhang H, Ji Y, Zhang X, Xiao RP, Zhang R, Lei M, Cyganek L, ... ... Boyett MR, et al. Stress-Activated Kinase MKK7 Governs Epigenetics of Cardiac Repolarization for Arrhythmia Prevention. Circulation. PMID 27899394 DOI: 10.1161/Circulationaha.116.022941  0.487
2016 Xiao Y, Cai X, Atkinson A, Logantha SJ, Boyett M, Dobrzynski H. Expression of connexin 43, ion channels and Ca(2+)-handling proteins in rat pulmonary vein cardiomyocytes. Experimental and Therapeutic Medicine. 12: 3233-3241. PMID 27882143 DOI: 10.3892/Etm.2016.3766  0.578
2016 Ashrafi R, Yon M, Pickavance L, Yanni Gerges J, Davis G, Wilding J, Jian K, Zhang H, Hart G, Boyett M. Altered Left Ventricular Ion Channel Transcriptome in a High-Fat-Fed Rat Model of Obesity: Insight into Obesity-Induced Arrhythmogenesis. Journal of Obesity. 2016: 7127898. PMID 27747100 DOI: 10.1155/2016/7127898  0.484
2016 Cheng H, James DPhil AF, Boyett MR, Hancox JC. Cardiac background sodium current: Elusive but important. Channels (Austin, Tex.). 0. PMID 27367468 DOI: 10.1080/19336950.2016.1207476  0.503
2016 Cheng H, Li J, James AF, Inada S, Choisy SC, Orchard CH, Zhang H, Boyett MR, Hancox JC. Characterization and influence of cardiac background sodium current in the atrioventricular node. Journal of Molecular and Cellular Cardiology. PMID 27132017 DOI: 10.1016/J.Yjmcc.2016.04.014  0.668
2015 Choudhury M, Boyett MR, Morris GM. Biology of the Sinus Node and its Disease. Arrhythmia & Electrophysiology Review. 4: 28-34. PMID 26835096 DOI: 10.15420/aer.2015.4.1.28  0.547
2015 Jue Li, Logantha SJ, Yanni J, Xue Cai, Dobrzynski H, Hart G, Boyett MR. From the Purkinje fibres to the ventricle: One dimensional computer simulation for the healthy and failing heart. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2015: 34-37. PMID 26736194 DOI: 10.1109/EMBC.2015.7318294  0.541
2015 Nikolaidou T, Cai XJ, Stephenson RS, Yanni J, Lowe T, Atkinson AJ, Jones CB, Sardar R, Corno AF, Dobrzynski H, Withers PJ, Jarvis JC, Hart G, Boyett MR. Congestive Heart Failure Leads to Prolongation of the PR Interval and Atrioventricular Junction Enlargement and Ion Channel Remodelling in the Rabbit. Plos One. 10: e0141452. PMID 26509807 DOI: 10.1371/journal.pone.0141452  0.544
2015 D'Souza A, Sharma S, Boyett MR. Rebuttal from Alicia D'Souza, Sanjay Sharma and Mark R. Boyett. The Journal of Physiology. 593: 1755. PMID 25871553 DOI: 10.1113/JP270256  0.365
2015 D'Souza A, Sharma S, Boyett MR. CrossTalk opposing view: bradycardia in the trained athlete is attributable to a downregulation of a pacemaker channel in the sinus node. The Journal of Physiology. 593: 1749-51. PMID 25871551 DOI: 10.1113/jphysiol.2014.284356  0.501
2015 Monfredi O, Zhang H, Boyett MR. Letter by monfredi et al regarding article, "physical activity and heart rate variability in older adults: The cardiovascular health study" Circulation. 131: e348. PMID 25691708 DOI: 10.1161/Circulationaha.114.011515  0.455
2014 Li J, Inada S, Schneider JE, Zhang H, Dobrzynski H, Boyett MR. Three-dimensional computer model of the right atrium including the sinoatrial and atrioventricular nodes predicts classical nodal behaviours. Plos One. 9: e112547. PMID 25380074 DOI: 10.1371/Journal.Pone.0112547  0.555
2014 Monfredi O, Lyashkov AE, Johnsen AB, Inada S, Schneider H, Wang R, Nirmalan M, Wisloff U, Maltsev VA, Lakatta EG, Zhang H, Boyett MR. Biophysical characterization of the underappreciated and important relationship between heart rate variability and heart rate. Hypertension. 64: 1334-43. PMID 25225208 DOI: 10.1161/Hypertensionaha.114.03782  0.514
2014 Taggart P, Orini M, Hanson B, Hayward M, Clayton R, Dobrzynski H, Yanni J, Boyett M, Lambiase PD. Developing a novel comprehensive framework for the investigation of cellular and whole heart electrophysiology in the in situ human heart: historical perspectives, current progress and future prospects. Progress in Biophysics and Molecular Biology. 115: 252-60. PMID 24972083 DOI: 10.1016/J.Pbiomolbio.2014.06.004  0.566
2014 D'Souza A, Bucchi A, Johnsen AB, Logantha SJ, Monfredi O, Yanni J, Prehar S, Hart G, Cartwright E, Wisloff U, Dobryznski H, DiFrancesco D, Morris GM, Boyett MR. Exercise training reduces resting heart rate via downregulation of the funny channel HCN4. Nature Communications. 5: 3775. PMID 24825544 DOI: 10.1038/ncomms4775  0.526
2014 Inada S, Zhang H, Tellez JO, Shibata N, Nakazawa K, Kamiya K, Kodama I, Mitsui K, Dobrzynski H, Boyett MR, Honjo H. Importance of gradients in membrane properties and electrical coupling in sinoatrial node pacing. Plos One. 9: e94565. PMID 24759974 DOI: 10.1371/Journal.Pone.0094565  0.53
2014 Yanni J, Maczewski M, Mackiewicz U, Siew S, Fedorenko O, Atkinson A, Price M, Beresewicz A, Anderson RH, Boyett MR, Dobrzynski H. Structural and functional alterations in the atrioventricular node and atrioventricular ring tissue in ischaemia-induced heart failure Histology and Histopathology. 29: 891-902. PMID 24368587  0.516
2014 DI Veroli GY, Davies MR, Zhang H, Abi-Gerges N, Boyett MR. hERG inhibitors with similar potency but different binding kinetics do not pose the same proarrhythmic risk: implications for drug safety assessment. Journal of Cardiovascular Electrophysiology. 25: 197-207. PMID 24118558 DOI: 10.1111/Jce.12289  0.398
2014 D'Souza A, Howarth FC, Yanni J, Dobrzynski H, Boyett MR, Adeghate E, Bidasee KR, Singh J. Chronic effects of mild hyperglycaemia on left ventricle transcriptional profile and structural remodelling in the spontaneously type 2 diabetic Goto-Kakizaki rat. Heart Failure Reviews. 19: 65-74. PMID 23430124 DOI: 10.1007/S10741-013-9376-9  0.488
2013 Aslanidi OV, Colman MA, Varela M, Zhao J, Smaill BH, Hancox JC, Boyett MR, Zhang H. Heterogeneous and anisotropic integrative model of pulmonary veins: computational study of arrhythmogenic substrate for atrial fibrillation. Interface Focus. 3: 20120069. PMID 24427522 DOI: 10.1098/Rsfs.2012.0069  0.493
2013 Corno AF, Cai X, Jones CB, Mondani G, Boyett MR, Jarvis JC, Hart G. Congestive heart failure: experimental model. Frontiers in Pediatrics. 1: 33. PMID 24400279 DOI: 10.3389/fped.2013.00033  0.491
2013 Atkinson AJ, Logantha SJ, Hao G, Yanni J, Fedorenko O, Sinha A, Gilbert SH, Benson AP, Buckley DL, Anderson RH, Boyett MR, Dobrzynski H. Functional, anatomical, and molecular investigation of the cardiac conduction system and arrhythmogenic atrioventricular ring tissue in the rat heart. Journal of the American Heart Association. 2: e000246. PMID 24356527 DOI: 10.1161/JAHA.113.000246  0.542
2013 Morris GM, Kalman JM, Boyett MR. Letter by Morris et al regarding article, "Low heart rates predict incident atrial fibrillation in healthy middle-aged men" by Grundvold et al. Circulation. Arrhythmia and Electrophysiology. 6: e101. PMID 24347601 DOI: 10.1161/CIRCEP.113.001033  0.434
2013 Inada S, Ono T, Shibata N, Iwata M, Haraguchi R, Ashihara T, Mitsui K, Boyett MR, Dobrzynski H, Nakazawa K. Simulation study of complex action potential conduction in atrioventricular node. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2013: 6850-3. PMID 24111318 DOI: 10.1109/EMBC.2013.6611131  0.554
2013 Monfredi O, Maltseva LA, Spurgeon HA, Boyett MR, Lakatta EG, Maltsev VA. Beat-to-Beat Variation in Periodicity of Local Calcium Releases Contributes to Intrinsic Variations of Spontaneous Cycle Length in Isolated Single Sinoatrial Node Cells. Plos One. 8: e67247. PMID 23826247 DOI: 10.1371/journal.pone.0067247  0.498
2013 Morris GM, D'Souza A, Dobrzynski H, Lei M, Choudhury M, Billeter R, Kryukova Y, Robinson RB, Kingston PA, Boyett MR. Characterization of a right atrial subsidiary pacemaker and acceleration of the pacing rate by HCN over-expression. Cardiovascular Research. 100: 160-9. PMID 23787003 DOI: 10.1093/Cvr/Cvt164  0.525
2013 Boyett MR, D'Souza A, Zhang H, Morris GM, Dobrzynski H, Monfredi O. Reply to Matelot, Schnell, Kervio, Thillaye du Boullay, and Carre. Journal of Applied Physiology (Bethesda, Md. : 1985). 114: 1757. PMID 23772054 DOI: 10.1152/Japplphysiol.00391.2013  0.483
2013 Colman MA, Aslanidi OV, Kharche S, Boyett MR, Garratt C, Hancox JC, Zhang H. Pro-arrhythmogenic effects of atrial fibrillation-induced electrical remodelling: Insights from the three-dimensional virtual human atria Journal of Physiology. 591: 4249-4272. PMID 23732649 DOI: 10.1113/Jphysiol.2013.254987  0.515
2013 Dobrzynski H, Anderson RH, Atkinson A, Borbas Z, D'Souza A, Fraser JF, Inada S, Logantha SJ, Monfredi O, Morris GM, Moorman AF, Nikolaidou T, Schneider H, Szuts V, Temple IP, ... ... Boyett MR, et al. Structure, function and clinical relevance of the cardiac conduction system, including the atrioventricular ring and outflow tract tissues. Pharmacology & Therapeutics. 139: 260-88. PMID 23612425 DOI: 10.1016/j.pharmthera.2013.04.010  0.616
2013 Boyett MR, D'Souza A, Zhang H, Morris GM, Dobrzynski H, Monfredi O. Viewpoint: is the resting bradycardia in athletes the result of remodeling of the sinoatrial node rather than high vagal tone? Journal of Applied Physiology (Bethesda, Md. : 1985). 114: 1351-5. PMID 23288551 DOI: 10.1152/Japplphysiol.01126.2012  0.519
2013 Anderson RH, Boyett MR, Dobrzynski H, Moorman AFM. The anatomy of the conduction system: Implications for the clinical cardiologist Journal of Cardiovascular Translational Research. 6: 187-196. PMID 23242580 DOI: 10.1007/s12265-012-9433-0  0.551
2013 Di Veroli GY, Davies MR, Zhang H, Abi-Gerges N, Boyett MR. High-throughput screening of drug-binding dynamics to HERG improves early drug safety assessment American Journal of Physiology - Heart and Circulatory Physiology. 304: H104-H117. PMID 23103500 DOI: 10.1152/Ajpheart.00511.2012  0.446
2013 Temple IP, Inada S, Dobrzynski H, Boyett MR. Connexins and the atrioventricular node. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 10: 297-304. PMID 23085482  0.542
2013 Aslanidi OV, Nikolaidou T, Zhao J, Smaill BH, Gilbert SH, Holden AV, Lowe T, Withers PJ, Stephenson RS, Jarvis JC, Hancox JC, Boyett MR, Zhang H. Application of micro-computed tomography with iodine staining to cardiac imaging, segmentation, and computational model development. Ieee Transactions On Medical Imaging. 32: 8-17. PMID 22829390 DOI: 10.1109/Tmi.2012.2209183  0.459
2012 Aslanidi OV, Colman MA, Zhao J, Smaill BH, Gilbert SH, Hancox JC, Boyett MR, Zhang H. Arrhythmogenic substrate for atrial fibrillation: insights from an integrative computational model of pulmonary veins. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2012: 203-6. PMID 23365867 DOI: 10.1109/EMBC.2012.6345906  0.478
2012 Zhang H, Butters T, Adeniran I, Higham J, Holden AV, Boyett MR, Hancox JC. Modeling the chronotropic effect of isoprenaline on rabbit sinoatrial node. Frontiers in Physiology. 3: 241. PMID 23060799 DOI: 10.3389/Fphys.2012.00241  0.498
2012 Hanson B, Gill J, Western D, Gilbey MP, Bostock J, Boyett MR, Zhang H, Coronel R, Taggart P. Cyclical modulation of human ventricular repolarization by respiration. Frontiers in Physiology. 3: 379. PMID 23055983 DOI: 10.3389/Fphys.2012.00379  0.5
2012 Abd Allah ESH, Aslanidi OV, Tellez JO, Yanni J, Billeter R, Zhang H, Dobrzynski H, Boyett MR. Postnatal development of transmural gradients in expression of ion channels and Ca 2+-handling proteins in the ventricle Journal of Molecular and Cellular Cardiology. 53: 145-155. PMID 22537893 DOI: 10.1016/J.Yjmcc.2012.04.004  0.489
2012 Stephenson RS, Boyett MR, Hart G, Nikolaidou T, Cai X, Corno AF, Alphonso N, Jeffery N, Jarvis JC. Contrast enhanced micro-computed tomography resolves the 3-dimensional morphology of the cardiac conduction system in mammalian hearts. Plos One. 7: e35299. PMID 22509404 DOI: 10.1371/journal.pone.0035299  0.521
2012 Kharche S, Adeniran I, Stott J, Law P, Boyett MR, Hancox JC, Zhang H. Pro-arrhythmogenic effects of the S140G KCNQ1 mutation in human atrial fibrillation - insights from modelling. The Journal of Physiology. 590: 4501-14. PMID 22508963 DOI: 10.1113/Jphysiol.2012.229146  0.481
2012 Marshall GE, Russell JA, Tellez JO, Jhund PS, Currie S, Dempster J, Boyett MR, Kane KA, Rankin AC, Workman AJ. Remodelling of human atrial K+ currents but not ion channel expression by chronic β-blockade. Pflã¼Gers Archiv : European Journal of Physiology. 463: 537-48. PMID 22160437 DOI: 10.1007/s00424-011-1061-z  0.477
2011 Morris GM, Monfredi O, Boyett MR. Not so fast! Sick sinus syndrome is a complex and incompletely understood disease that might prove hard to model in animals. Cardiovascular Research. 92: 178; author reply 17. PMID 21791463 DOI: 10.1093/cvr/cvr204  0.398
2011 Aslanidi OV, Colman MA, Stott J, Dobrzynski H, Boyett MR, Holden AV, Zhang H. 3D virtual human atria: A computational platform for studying clinical atrial fibrillation. Progress in Biophysics and Molecular Biology. 107: 156-68. PMID 21762716 DOI: 10.1016/J.Pbiomolbio.2011.06.011  0.52
2011 Atkinson A, Inada S, Li J, Tellez JO, Yanni J, Sleiman R, Allah EA, Anderson RH, Zhang H, Boyett MR, Dobrzynski H. Anatomical and molecular mapping of the left and right ventricular His-Purkinje conduction networks Journal of Molecular and Cellular Cardiology. 51: 689-701. PMID 21741388 DOI: 10.1016/J.Yjmcc.2011.05.020  0.536
2011 D'Souza A, Howarth FC, Yanni J, Dobryznski H, Boyett MR, Adeghate E, Bidasee KR, Singh J. Left ventricle structural remodelling in the prediabetic Goto-Kakizaki rat. Experimental Physiology. 96: 875-88. PMID 21622965 DOI: 10.1113/Expphysiol.2011.058271  0.474
2011 Chandler N, Aslanidi O, Buckley D, Inada S, Birchall S, Atkinson A, Kirk D, Monfredi O, Molenaar P, Anderson R, Sharma V, Sigg D, Zhang H, Boyett M, Dobrzynski H. Computer three-dimensional anatomical reconstruction of the human sinus node and a novel paranodal area. Anatomical Record (Hoboken, N.J. : 2007). 294: 970-9. PMID 21538926 DOI: 10.1002/Ar.21379  0.56
2011 Hao X, Zhang Y, Zhang X, Nirmalan M, Davies L, Konstantinou D, Yin F, Dobrzynski H, Wang X, Grace A, Zhang H, Boyett M, Huang CLH, Lei M. TGF-β1-mediated fibrosis and ion channel remodeling are key mechanisms in producing the sinus node dysfunction associated with SCN5A deficiency and aging Circulation: Arrhythmia and Electrophysiology. 4: 397-406. PMID 21493874 DOI: 10.1161/Circep.110.960807  0.554
2011 Zi M, Kimura TE, Liu W, Jin J, Higham J, Kharche S, Hao G, Shi Y, Shen W, Prehar S, Mironov A, Neyses L, Bierhuizen MF, Boyett MR, Zhang H, et al. Mitogen-activated protein kinase kinase 4 deficiency in cardiomyocytes causes connexin 43 reduction and couples hypertrophic signals to ventricular arrhythmogenesis. The Journal of Biological Chemistry. 286: 17821-30. PMID 21454599 DOI: 10.1074/Jbc.M111.228791  0.495
2011 Allah EA, Tellez JO, Yanni J, Nelson T, Monfredi O, Boyett MR, Dobrzynski H. Changes in the expression of ion channels, connexins and Ca2+-handling proteins in the sino-atrial node during postnatal development Experimental Physiology. 96: 426-438. PMID 21278078 DOI: 10.1113/expphysiol.2010.055780  0.524
2010 Monfredi O, Dobrzynski H, Mondal T, Boyett MR, Morris GM. The anatomy and physiology of the sinoatrial node--a contemporary review. Pacing and Clinical Electrophysiology : Pace. 33: 1392-406. PMID 20946278 DOI: 10.1111/j.1540-8159.2010.02838.x  0.577
2010 Aslanidi OV, Sleiman RN, Boyett MR, Hancox JC, Zhang H. Ionic mechanisms for electrical heterogeneity between rabbit purkinje fiber and ventricular cells Biophysical Journal. 98: 2420-2431. PMID 20513385 DOI: 10.1016/J.Bpj.2010.02.033  0.527
2010 Butters TD, Aslanidi OV, Inada S, Boyett MR, Hancox JC, Lei M, Zhang H. Mechanistic links between Na+ channel (SCN5A) mutations and impaired cardiac pacemaking in sick sinus syndrome Circulation Research. 107: 126-137. PMID 20448214 DOI: 10.1161/Circresaha.110.219949  0.511
2010 Xiao YF, Chandler N, Dobrzynski H, Richardson ES, Tenbroek EM, Wilhelm JJ, Sharma V, Varghese A, Boyett MR, Iaizzo PA, Sigg DC. Hysteresis in human HCN4 channels: a crucial feature potentially affecting sinoatrial node pacemaking. Sheng Li Xue Bao : [Acta Physiologica Sinica]. 62: 1-13. PMID 20179882  0.538
2009 Aslanidi OV, Robinson R, Cheverton D, Boyett MR, Zhang H. Electrophysiological substrate for a dominant reentrant source during atrial fibrillation. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 2819-22. PMID 19964268 DOI: 10.1109/IEMBS.2009.5333573  0.485
2009 Greener ID, Tellez JO, Dobrzynski H, Yamamoto M, Graham GM, Billeter R, Boyett MR. Ion channel transcript expression at the rabbit atrioventricular conduction axis. Circulation. Arrhythmia and Electrophysiology. 2: 305-15. PMID 19808481 DOI: 10.1161/CIRCEP.108.803569  0.532
2009 Morris GM, Boyett MR. Perspectives -- biological pacing, a clinical reality? Therapeutic Advances in Cardiovascular Disease. 3: 479-83. PMID 19717570 DOI: 10.1177/1753944709345792  0.472
2009 Boyett MR. 'And the beat goes on.' The cardiac conduction system: the wiring system of the heart. Experimental Physiology. 94: 1035-49. PMID 19592411 DOI: 10.1113/expphysiol.2009.046920  0.607
2009 Aslanidi OV, Stewart P, Boyett MR, Zhang H. Optimal velocity and safety of discontinuous conduction through the heterogeneous Purkinje-ventricular junction. Biophysical Journal. 97: 20-39. PMID 19580741 DOI: 10.1016/J.Bpj.2009.03.061  0.483
2009 Stewart P, Aslanidi OV, Noble D, Noble PJ, Boyett MR, Zhang H. Mathematical models of the electrical action potential of Purkinje fibre cells. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 367: 2225-55. PMID 19414454 DOI: 10.1098/Rsta.2008.0283  0.567
2009 Brioschi C, Micheloni S, Tellez JO, Pisoni G, Longhi R, Moroni P, Billeter R, Barbuti A, Dobrzynski H, Boyett MR, DiFrancesco D, Baruscotti M. Distribution of the pacemaker HCN4 channel mRNA and protein in the rabbit sinoatrial node. Journal of Molecular and Cellular Cardiology. 47: 221-7. PMID 19394343 DOI: 10.1016/j.yjmcc.2009.04.009  0.518
2009 Yanni J, Boyett MR, Anderson RH, Dobrzynski H. The extent of the specialized atrioventricular ring tissues. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 6: 672-80. PMID 19328044 DOI: 10.1016/j.hrthm.2009.01.021  0.504
2009 Chandler NJ, Greener ID, Tellez JO, Inada S, Musa H, Molenaar P, Difrancesco D, Baruscotti M, Longhi R, Anderson RH, Billeter R, Sharma V, Sigg DC, Boyett MR, Dobrzynski H. Molecular architecture of the human sinus node: insights into the function of the cardiac pacemaker. Circulation. 119: 1562-75. PMID 19289639 DOI: 10.1161/Circulationaha.108.804369  0.504
2009 Musa H, Tellez JO, Chandler NJ, Greener ID, Maczewski M, Mackiewicz U, Beresewicz A, Molenaar P, Boyett MR, Dobrzynski H. P2 purinergic receptor mRNA in rat and human sinoatrial node and other heart regions. Naunyn-Schmiedeberg's Archives of Pharmacology. 379: 541-9. PMID 19234689 DOI: 10.1007/S00210-009-0403-2  0.496
2009 Aslanidi OV, Boyett MR, Dobrzynski H, Li J, Zhang H. Mechanisms of transition from normal to reentrant electrical activity in a model of rabbit atrial tissue: interaction of tissue heterogeneity and anisotropy. Biophysical Journal. 96: 798-817. PMID 19186122 DOI: 10.1016/J.Bpj.2008.09.057  0.489
2009 Mackiewicz U, Maczewski M, Konior A, Tellez JO, Nowis D, Dobrzynski H, Boyett MR, Lewartowski B. Sarcolemmal Ca2+-ATPase ability to transport Ca2+ gradually diminishes after myocardial infarction in the rat. Cardiovascular Research. 81: 546-54. PMID 18948275 DOI: 10.1093/cvr/cvn285  0.457
2009 Anderson RH, Yanni J, Boyett MR, Chandler NJ, Dobrzynski H. The anatomy of the cardiac conduction system. Clinical Anatomy (New York, N.Y.). 22: 99-113. PMID 18773472 DOI: 10.1002/ca.20700  0.549
2008 Jones SA, Yamamoto M, Tellez JO, Billeter R, Boyett MR, Honjo H, Lancaster MK. Distinguishing properties of cells from the myocardial sleeves of the pulmonary veins: a comparison of normal and abnormal pacemakers. Circulation. Arrhythmia and Electrophysiology. 1: 39-48. PMID 19808392 DOI: 10.1161/CIRCEP.107.748467  0.52
2008 Aslanidi OV, Dewey RS, Morgan AR, Boyett MR, Zhang H. Regional differences in rabbit atrial action potential properties: mechanisms, consequences and pharmacological implications. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2008: 141-4. PMID 19162613 DOI: 10.1109/IEMBS.2008.4649110  0.491
2008 Kharche S, Garratt CJ, Boyett MR, Inada S, Holden AV, Hancox JC, Zhang H. Atrial proarrhythmia due to increased inward rectifier current (IK1) arising from KCNJ2 mutation - A simulation study Progress in Biophysics and Molecular Biology. 98: 186-197. PMID 19041665 DOI: 10.1016/J.Pbiomolbio.2008.10.010  0.493
2008 Li J, Greener ID, Inada S, Nikolski VP, Yamamoto M, Hancox JC, Zhang H, Billeter R, Efimov IR, Dobrzynski H, Boyett MR. Computer three-dimensional reconstruction of the atrioventricular node. Circulation Research. 102: 975-85. PMID 18309098 DOI: 10.1161/Circresaha.108.172403  0.548
2008 Liu J, Noble PJ, Xiao G, Abdelrahman M, Dobrzynski H, Boyett MR, Lei M, Noble D. Role of pacemaking current in cardiac nodes: insights from a comparative study of sinoatrial node and atrioventricular node. Progress in Biophysics and Molecular Biology. 96: 294-304. PMID 17905415 DOI: 10.1016/J.Pbiomolbio.2007.07.009  0.548
2008 Nikmaram MR, Liu J, Abdelrahman M, Dobrzynski H, Boyett MR, Lei M. Characterization of the effects of ryanodine, TTX, E-4031 and 4-AP on the sinoatrial and atrioventricular nodes. Progress in Biophysics and Molecular Biology. 96: 452-64. PMID 17850852 DOI: 10.1016/J.Pbiomolbio.2007.07.003  0.51
2007 Dobrzynski H, Boyett MR, Anderson RH. New insights into pacemaker activity: promoting understanding of sick sinus syndrome. Circulation. 115: 1921-32. PMID 17420362 DOI: 10.1161/CIRCULATIONAHA.106.616011  0.409
2007 Liu B, Westhead DR, Boyett MR, Warwicker J. Modelling the pH-dependent properties of Kv1 potassium channels. Journal of Molecular Biology. 368: 328-35. PMID 17359997 DOI: 10.1016/j.jmb.2007.02.041  0.462
2007 Jones SA, Boyett MR, Lancaster MK. Declining into failure: the age-dependent loss of the L-type calcium channel within the sinoatrial node. Circulation. 115: 1183-90. PMID 17339548 DOI: 10.1161/CIRCULATIONAHA.106.663070  0.545
2007 Liu J, Dobrzynski H, Yanni J, Boyett MR, Lei M. Organisation of the mouse sinoatrial node: structure and expression of HCN channels. Cardiovascular Research. 73: 729-38. PMID 17222809 DOI: 10.1016/J.Cardiores.2006.11.016  0.525
2006 Tellez JO, Dobrzynski H, Greener ID, Graham GM, Laing E, Honjo H, Hubbard SJ, Boyett MR, Billeter R. Differential expression of ion channel transcripts in atrial muscle and sinoatrial node in rabbit. Circulation Research. 99: 1384-93. PMID 17082478 DOI: 10.1161/01.RES.0000251717.98379.69  0.501
2006 Dobrzynski H, Boyett MR. What do we learn from double Cx40/Cx45-deficient mice about cardiac morphogenetic defects and conduction abnormalities? Journal of Molecular and Cellular Cardiology. 41: 774-7. PMID 17014863 DOI: 10.1016/j.yjmcc.2006.08.014  0.442
2006 Yamamoto M, Dobrzynski H, Tellez J, Niwa R, Billeter R, Honjo H, Kodama I, Boyett MR. Extended atrial conduction system characterised by the expression of the HCN4 channel and connexin45. Cardiovascular Research. 72: 271-81. PMID 16989793 DOI: 10.1016/j.cardiores.2006.07.026  0.543
2006 Yoo S, Dobrzynski H, Fedorov VV, Xu SZ, Yamanushi TT, Jones SA, Yamamoto M, Nikolski VP, Efimov IR, Boyett MR. Localization of Na+ channel isoforms at the atrioventricular junction and atrioventricular node in the rat. Circulation. 114: 1360-71. PMID 16966585 DOI: 10.1161/Circulationaha.106.613182  0.532
2006 Barnes K, Dobrzynski H, Foppolo S, Beal PR, Ismat F, Scullion ER, Sun L, Tellez J, Ritzel MW, Claycomb WC, Cass CE, Young JD, Billeter-Clark R, Boyett MR, Baldwin SA. Distribution and functional characterization of equilibrative nucleoside transporter-4, a novel cardiac adenosine transporter activated at acidic pH. Circulation Research. 99: 510-9. PMID 16873718 DOI: 10.1161/01.Res.0000238359.18495.42  0.469
2006 Dubuis E, Rockliffe N, Hussain M, Boyett M, Wray D, Gawler D. Evidence for multiple Src binding sites on the alpha1c L-type Ca2+ channel and their roles in activity regulation. Cardiovascular Research. 69: 391-401. PMID 16352297 DOI: 10.1016/J.Cardiores.2005.11.006  0.446
2005 Boyett MR, Li J, Inada S, Dobrzynski H, Schneider JE, Holden AV, Zhang H. Imaging the heart: computer 3-dimensional anatomic models of the heart. Journal of Electrocardiology. 38: 113-20. PMID 16226085 DOI: 10.1016/J.Jelectrocard.2005.06.102  0.541
2005 Makary SM, Claydon TW, Enkvetchakul D, Nichols CG, Boyett MR. A difference in inward rectification and polyamine block and permeation between the Kir2.1 and Kir3.1/Kir3.4 K+ channels. The Journal of Physiology. 568: 749-66. PMID 16109731 DOI: 10.1113/jphysiol.2005.085746  0.618
2004 Efimov IR, Nikolski VP, Rothenberg F, Greener ID, Li J, Dobrzynski H, Boyett M. Structure-function relationship in the AV junction. The Anatomical Record. Part a, Discoveries in Molecular, Cellular, and Evolutionary Biology. 280: 952-65. PMID 15368340 DOI: 10.1002/Ar.A.20108  0.595
2004 Jones SA, Lancaster MK, Boyett MR. Ageing-related changes of connexins and conduction within the sinoatrial node. The Journal of Physiology. 560: 429-37. PMID 15308686 DOI: 10.1113/jphysiol.2004.072108  0.53
2004 Lei M, Jones SA, Liu J, Lancaster MK, Fung SS, Dobrzynski H, Camelliti P, Maier SK, Noble D, Boyett MR. Requirement of neuronal- and cardiac-type sodium channels for murine sinoatrial node pacemaking. The Journal of Physiology. 559: 835-48. PMID 15254155 DOI: 10.1113/Jphysiol.2004.068643  0.568
2004 Lancaster MK, Jones SA, Harrison SM, Boyett MR. Intracellular Ca2+ and pacemaking within the rabbit sinoatrial node: heterogeneity of role and control. The Journal of Physiology. 556: 481-94. PMID 14724216 DOI: 10.1113/Jphysiol.2003.057372  0.432
2003 Garny A, Kohl P, Hunter PJ, Boyett MR, Noble D. One-dimensional rabbit sinoatrial node models: benefits and limitations. Journal of Cardiovascular Electrophysiology. 14: S121-32. PMID 14760914 DOI: 10.1046/J.1540.8167.90301.X  0.549
2003 Leach RN, Boyett MR, Findlay JB. Expression, purification and spectroscopic studies of full-length Kir3.1 channel C-terminus. Biochimica Et Biophysica Acta. 1652: 83-90. PMID 14644043  0.431
2003 Dobrzynski H, Nikolski VP, Sambelashvili AT, Greener ID, Yamamoto M, Boyett MR, Efimov IR. Site of origin and molecular substrate of atrioventricular junctional rhythm in the rabbit heart. Circulation Research. 93: 1102-10. PMID 14563715 DOI: 10.1161/01.Res.0000101913.95604.B9  0.57
2003 Claydon TW, Makary SY, Dibb KM, Boyett MR. The selectivity filter may act as the agonist-activated gate in the G protein-activated Kir3.1/Kir3.4 K+ channel. The Journal of Biological Chemistry. 278: 50654-63. PMID 14525972 DOI: 10.1074/jbc.M308183200  0.446
2003 Dibb KM, Rose T, Makary SY, Claydon TW, Enkvetchakul D, Leach R, Nichols CG, Boyett MR. Molecular basis of ion selectivity, block, and rectification of the inward rectifier Kir3.1/Kir3.4 K(+) channel. The Journal of Biological Chemistry. 278: 49537-48. PMID 14504281 DOI: 10.1074/jbc.M307723200  0.586
2003 Honjo H, Boyett MR, Niwa R, Inada S, Yamamoto M, Mitsui K, Horiuchi T, Shibata N, Kamiya K, Kodama I. Pacing-induced spontaneous activity in myocardial sleeves of pulmonary veins after treatment with ryanodine. Circulation. 107: 1937-43. PMID 12668519 DOI: 10.1161/01.CIR.0000062645.38670.BD  0.45
2003 Maier SK, Westenbroek RE, Yamanushi TT, Dobrzynski H, Boyett MR, Catterall WA, Scheuer T. An unexpected requirement for brain-type sodium channels for control of heart rate in the mouse sinoatrial node. Proceedings of the National Academy of Sciences of the United States of America. 100: 3507-12. PMID 12631690 DOI: 10.1073/pnas.2627986100  0.55
2003 Boyett MR, Dobrzynski H, Lancaster MK, Jones SA, Honjo H, Kodama I. Sophisticated architecture is required for the sinoatrial node to perform its normal pacemaker function. Journal of Cardiovascular Electrophysiology. 14: 104-6. PMID 12625620 DOI: 10.1046/j.1540-8167.2003.02307.x  0.542
2003 Khatib SY, Boyett MR. Effects of glyburide (glibenclamide) on myocardial function in Langendorff perfused rabbit heart and on myocardial contractility and slow calcium current in guinea-pig single myocytes. Molecular and Cellular Biochemistry. 242: 81-7. PMID 12619869  0.488
2003 Nikolski VP, Jones SA, Lancaster MK, Boyett MR, Efimov IR. Cx43 and dual-pathway electrophysiology of the atrioventricular node and atrioventricular nodal reentry. Circulation Research. 92: 469-75. PMID 12600895 DOI: 10.1161/01.Res.0000059304.97120.2F  0.503
2003 Taggart P, Sutton P, Chalabi Z, Boyett MR, Simon R, Elliott D, Gill JS. Effect of adrenergic stimulation on action potential duration restitution in humans. Circulation. 107: 285-9. PMID 12538429  0.485
2002 Kodama I, Honjo H, Boyett MR. Are we lost in the labyrinth of the sinoatrial node pacemaker mechanism? Journal of Cardiovascular Electrophysiology. 13: 1303-5. PMID 12521351  0.499
2002 Zhang H, Holden AV, Boyett MR. Sustained inward current and pacemaker activity of mammalian sinoatrial node. Journal of Cardiovascular Electrophysiology. 13: 809-12. PMID 12212702 DOI: 10.1046/J.1540-8167.2002.00809.X  0.477
2002 Jones SA, Morton MJ, Hunter M, Boyett MR. Expression of TASK-1, a pH-sensitive twin-pore domain K(+) channel, in rat myocytes. American Journal of Physiology. Heart and Circulatory Physiology. 283: H181-5. PMID 12063289 DOI: 10.1152/Ajpheart.00963.2001  0.463
2002 Zhang H, Holden AV, Noble D, Boyett MR. Analysis of the chronotropic effect of acetylcholine on sinoatrial node cells. Journal of Cardiovascular Electrophysiology. 13: 465-74. PMID 12030529 DOI: 10.1046/J.1540-8167.2002.00465.X  0.464
2002 Musa H, Lei M, Honjo H, Jones SA, Dobrzynski H, Lancaster MK, Takagishi Y, Henderson Z, Kodama I, Boyett MR. Heterogeneous expression of Ca(2+) handling proteins in rabbit sinoatrial node. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 50: 311-24. PMID 11850434 DOI: 10.1177/002215540205000303  0.496
2002 Honjo H, Boyett MR, Coppen SR, Takagishi Y, Opthof T, Severs NJ, Kodama I. Heterogeneous expression of connexins in rabbit sinoatrial node cells: correlation between connexin isotype and cell size. Cardiovascular Research. 53: 89-96. PMID 11744016  0.5
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