Nick Westwood - Publications

Affiliations: 
Chemistry University of St. Andrews, Saint Andrews, Scotland, United Kingdom 

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Coufalova D, Remnant L, Hernychova L, Muller P, Healy A, Kannan S, Vojtesek B, Westwood N, Verma CS, Vojtesek B, Hupp TR, Houston DR. An inter-subunit protein-peptide interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone Reptin. Journal of Proteomics. PMID 30862565 DOI: 10.1016/J.Jprot.2019.02.012  0.537
2015 Healy AR, Izumikawa M, Slawin AM, Shin-Ya K, Westwood NJ. Stereochemical Assignment of the Protein-Protein Interaction Inhibitor JBIR-22 by Total Synthesis. Angewandte Chemie (Weinheim An Der Bergstrasse, Germany). 127: 4118-4122. PMID 27087707 DOI: 10.1002/ange.201411141  0.574
2015 Healy AR, Westwood NJ. Synthetic studies on the bioactive tetramic acid JBIR-22 using a late stage Diels-Alder reaction. Organic & Biomolecular Chemistry. 13: 10527-31. PMID 26337398 DOI: 10.1039/c5ob01771h  0.514
2015 Healy AR, Izumikawa M, Slawin AM, Shin-Ya K, Westwood NJ. Stereochemical assignment of the protein-protein interaction inhibitor JBIR-22 by total synthesis. Angewandte Chemie (International Ed. in English). 54: 4046-50. PMID 25650886 DOI: 10.1002/Anie.201411141  0.574
2015 Healy AR, Vinale F, Lorito M, Westwood NJ. Total synthesis and biological evaluation of the tetramic acid based natural product harzianic acid and its stereoisomers. Organic Letters. 17: 692-5. PMID 25629709 DOI: 10.1021/ol503717r  0.544
2015 Healy AR, Houston DR, Remnant L, Huart AS, Brychtova V, Maslon MM, Meers O, Muller P, Krejci A, Blackburn EA, Vojtesek B, Hernychova L, Walkinshaw MD, Westwood NJ, Hupp TR. Discovery of a novel ligand that modulates the protein-protein interactions of the AAA+ superfamily oncoprotein reptin Chemical Science. 6: 3109-3116. DOI: 10.1039/c4sc03885a  0.482
2010 WESTWOOD NJ, SCHOFIELD CJ, CLARIDGE TDW. ChemInform Abstract: Studies on the Reactivity of Azetidin-2-ones in Phosphate Buffer. Cheminform. 29: no-no. DOI: 10.1002/chin.199802245  0.317
2010 ADLINGTON RM, BALDWIN JE, MCCOULL W, PRITCHARD GJ, SCHOFIELD CJ, WESTWOOD NJ. ChemInform Abstract: An Investigation of the N-Arylsulfonylation of 2-Azetidinones. Cheminform. 28: no-no. DOI: 10.1002/chin.199752129  0.408
2001 Pelish HE, Westwood NJ, Feng Y, Kirchhausen T, Shair MD. Use of biomimetic diversity-oriented synthesis to discover galanthamine-like molecules with biological properties beyond those of the natural product. Journal of the American Chemical Society. 123: 6740-1. PMID 11439080 DOI: 10.1021/Ja016093H  0.683
2001 Tallarico JA, Depew KM, Pelish HE, Westwood NJ, Lindsley CW, Shair MD, Schreiber SL, Foley MA. An alkylsilyl-tethered, high-capacity solid support amenable to diversity-oriented synthesis for one-bead, one-stock solution chemical genetics. Journal of Combinatorial Chemistry. 3: 312-8. PMID 11350255 DOI: 10.1021/Cc000107I  0.646
1999 Wilmouth RC, Kassamally S, Westwood NJ, Sheppard RJ, Claridge TD, Aplin RT, Wright PA, Pritchard GJ, Schofield CJ. Mechanistic insights into the inhibition of serine proteases by monocyclic lactams. Biochemistry. 38: 7989-98. PMID 10387042 DOI: 10.1021/Bi990098Y  0.418
1999 Magnus P, Westwood N, Spyvee M, Frost C, Linnane P, Tavares F, Lynch V. Taxane diterpenes 5: Synthesis of the A- and C-rings: An unusual rearrangement of an N-hydroxyimino lactone Tetrahedron. 55: 6435-6452. DOI: 10.1016/S0040-4020(99)00305-1  0.528
1998 Wilmouth RC, Westwood NJ, Anderson K, Brownlee W, Claridge TD, Clifton IJ, Pritchard GJ, Aplin RT, Schofield CJ. Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex. Biochemistry. 37: 17506-13. PMID 9860865 DOI: 10.1021/Bi9816249  0.575
1997 Wilmouth RC, Clifton IJ, Robinson CV, Roach PL, Aplin RT, Westwood NJ, Hajdu J, Schofield CJ. Structure of a specific acyl-enzyme complex formed between beta-casomorphin-7 and porcine pancreatic elastase. Nature Structural Biology. 4: 456-62. PMID 9187653 DOI: 10.1038/Nsb0697-456  0.579
1997 Adlington RM, Baldwin JE, MC Coull W, Pritchard GJ, Schofield CJ, Westwood NJ. An Investigation of the N-Arylsulfonylation of 2-Azetidinones Synthetic Communications. 27: 3803-3813. DOI: 10.1080/00397919708007305  0.473
1997 Westwood NJ, Claridge TD, Edwards PN, Schofield CJ. Reversible acylation of elastase by γ-lactam analogues of β-lactam inhibitors Bioorganic & Medicinal Chemistry Letters. 7: 2973-2978. DOI: 10.1016/S0960-894X(97)10123-8  0.376
1997 Magnus P, Tavares F, Westwood N. Enantioselective synthesis of a taxane C-ring component using the Schultz asymmetric Birch reduction methodology Tetrahedron Letters. 38: 1341-1344. DOI: 10.1016/S0040-4039(97)00094-4  0.516
1996 Magnus P, Ujjainwalla F, Westwood N, Lynch V. Isomerization, autooxidation and epimerization for the introduction of C-1 to C-5 functionality into the taxane ABC ring system Tetrahedron Letters. 37: 6639-6642. DOI: 10.1016/S0040-4039(96)01495-5  0.479
1994 Aplin RT, Robinson CV, Schofield CJ, Westwood NJ. Does the observation of noncovalent complexes between biomolecules by electrospray ionisation mass spectrometry necessarily reflect specific solution interactions? Journal of the Chemical Society, Chemical Communications. 2415-2417. DOI: 10.1039/C39940002415  0.365
1993 Aplin RT, Robinson CV, Schofield CJ, Westwood NJ. An investigation into the mechanism of elastase inhibition by cephalosporins using electrospray ionisation mass spectrometry Tetrahedron. 49: 10903-10912. DOI: 10.1016/S0040-4020(01)80243-X  0.339
1992 Aplin RT, Robinson CV, Schofield CJ, Westwood NJ. Studies on the inhibition of porcine pancreatic elastase using electrospray mass spectrometry Journal of the Chemical Society, Chemical Communications. 1650-1652. DOI: 10.1039/C39920001650  0.323
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