Year |
Citation |
Score |
2019 |
Coufalova D, Remnant L, Hernychova L, Muller P, Healy A, Kannan S, Vojtesek B, Westwood N, Verma CS, Vojtesek B, Hupp TR, Houston DR. An inter-subunit protein-peptide interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone Reptin. Journal of Proteomics. PMID 30862565 DOI: 10.1016/J.Jprot.2019.02.012 |
0.537 |
|
2015 |
Healy AR, Izumikawa M, Slawin AM, Shin-Ya K, Westwood NJ. Stereochemical Assignment of the Protein-Protein Interaction Inhibitor JBIR-22 by Total Synthesis. Angewandte Chemie (Weinheim An Der Bergstrasse, Germany). 127: 4118-4122. PMID 27087707 DOI: 10.1002/ange.201411141 |
0.574 |
|
2015 |
Healy AR, Westwood NJ. Synthetic studies on the bioactive tetramic acid JBIR-22 using a late stage Diels-Alder reaction. Organic & Biomolecular Chemistry. 13: 10527-31. PMID 26337398 DOI: 10.1039/c5ob01771h |
0.514 |
|
2015 |
Healy AR, Izumikawa M, Slawin AM, Shin-Ya K, Westwood NJ. Stereochemical assignment of the protein-protein interaction inhibitor JBIR-22 by total synthesis. Angewandte Chemie (International Ed. in English). 54: 4046-50. PMID 25650886 DOI: 10.1002/Anie.201411141 |
0.574 |
|
2015 |
Healy AR, Vinale F, Lorito M, Westwood NJ. Total synthesis and biological evaluation of the tetramic acid based natural product harzianic acid and its stereoisomers. Organic Letters. 17: 692-5. PMID 25629709 DOI: 10.1021/ol503717r |
0.544 |
|
2015 |
Healy AR, Houston DR, Remnant L, Huart AS, Brychtova V, Maslon MM, Meers O, Muller P, Krejci A, Blackburn EA, Vojtesek B, Hernychova L, Walkinshaw MD, Westwood NJ, Hupp TR. Discovery of a novel ligand that modulates the protein-protein interactions of the AAA+ superfamily oncoprotein reptin Chemical Science. 6: 3109-3116. DOI: 10.1039/c4sc03885a |
0.482 |
|
2010 |
WESTWOOD NJ, SCHOFIELD CJ, CLARIDGE TDW. ChemInform Abstract: Studies on the Reactivity of Azetidin-2-ones in Phosphate Buffer. Cheminform. 29: no-no. DOI: 10.1002/chin.199802245 |
0.317 |
|
2010 |
ADLINGTON RM, BALDWIN JE, MCCOULL W, PRITCHARD GJ, SCHOFIELD CJ, WESTWOOD NJ. ChemInform Abstract: An Investigation of the N-Arylsulfonylation of 2-Azetidinones. Cheminform. 28: no-no. DOI: 10.1002/chin.199752129 |
0.408 |
|
2001 |
Pelish HE, Westwood NJ, Feng Y, Kirchhausen T, Shair MD. Use of biomimetic diversity-oriented synthesis to discover galanthamine-like molecules with biological properties beyond those of the natural product. Journal of the American Chemical Society. 123: 6740-1. PMID 11439080 DOI: 10.1021/Ja016093H |
0.683 |
|
2001 |
Tallarico JA, Depew KM, Pelish HE, Westwood NJ, Lindsley CW, Shair MD, Schreiber SL, Foley MA. An alkylsilyl-tethered, high-capacity solid support amenable to diversity-oriented synthesis for one-bead, one-stock solution chemical genetics. Journal of Combinatorial Chemistry. 3: 312-8. PMID 11350255 DOI: 10.1021/Cc000107I |
0.646 |
|
1999 |
Wilmouth RC, Kassamally S, Westwood NJ, Sheppard RJ, Claridge TD, Aplin RT, Wright PA, Pritchard GJ, Schofield CJ. Mechanistic insights into the inhibition of serine proteases by monocyclic lactams. Biochemistry. 38: 7989-98. PMID 10387042 DOI: 10.1021/Bi990098Y |
0.418 |
|
1999 |
Magnus P, Westwood N, Spyvee M, Frost C, Linnane P, Tavares F, Lynch V. Taxane diterpenes 5: Synthesis of the A- and C-rings: An unusual rearrangement of an N-hydroxyimino lactone Tetrahedron. 55: 6435-6452. DOI: 10.1016/S0040-4020(99)00305-1 |
0.528 |
|
1998 |
Wilmouth RC, Westwood NJ, Anderson K, Brownlee W, Claridge TD, Clifton IJ, Pritchard GJ, Aplin RT, Schofield CJ. Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex. Biochemistry. 37: 17506-13. PMID 9860865 DOI: 10.1021/Bi9816249 |
0.575 |
|
1997 |
Wilmouth RC, Clifton IJ, Robinson CV, Roach PL, Aplin RT, Westwood NJ, Hajdu J, Schofield CJ. Structure of a specific acyl-enzyme complex formed between beta-casomorphin-7 and porcine pancreatic elastase. Nature Structural Biology. 4: 456-62. PMID 9187653 DOI: 10.1038/Nsb0697-456 |
0.579 |
|
1997 |
Adlington RM, Baldwin JE, MC Coull W, Pritchard GJ, Schofield CJ, Westwood NJ. An Investigation of the N-Arylsulfonylation of 2-Azetidinones Synthetic Communications. 27: 3803-3813. DOI: 10.1080/00397919708007305 |
0.473 |
|
1997 |
Westwood NJ, Claridge TD, Edwards PN, Schofield CJ. Reversible acylation of elastase by γ-lactam analogues of β-lactam inhibitors Bioorganic & Medicinal Chemistry Letters. 7: 2973-2978. DOI: 10.1016/S0960-894X(97)10123-8 |
0.376 |
|
1997 |
Magnus P, Tavares F, Westwood N. Enantioselective synthesis of a taxane C-ring component using the Schultz asymmetric Birch reduction methodology Tetrahedron Letters. 38: 1341-1344. DOI: 10.1016/S0040-4039(97)00094-4 |
0.516 |
|
1996 |
Magnus P, Ujjainwalla F, Westwood N, Lynch V. Isomerization, autooxidation and epimerization for the introduction of C-1 to C-5 functionality into the taxane ABC ring system Tetrahedron Letters. 37: 6639-6642. DOI: 10.1016/S0040-4039(96)01495-5 |
0.479 |
|
1994 |
Aplin RT, Robinson CV, Schofield CJ, Westwood NJ. Does the observation of noncovalent complexes between biomolecules by electrospray ionisation mass spectrometry necessarily reflect specific solution interactions? Journal of the Chemical Society, Chemical Communications. 2415-2417. DOI: 10.1039/C39940002415 |
0.365 |
|
1993 |
Aplin RT, Robinson CV, Schofield CJ, Westwood NJ. An investigation into the mechanism of elastase inhibition by cephalosporins using electrospray ionisation mass spectrometry Tetrahedron. 49: 10903-10912. DOI: 10.1016/S0040-4020(01)80243-X |
0.339 |
|
1992 |
Aplin RT, Robinson CV, Schofield CJ, Westwood NJ. Studies on the inhibition of porcine pancreatic elastase using electrospray mass spectrometry Journal of the Chemical Society, Chemical Communications. 1650-1652. DOI: 10.1039/C39920001650 |
0.323 |
|
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