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David T. Curiel - Publications

Affiliations: 
1993-2011 Medicine University of Alabama, Birmingham, Birmingham, AL, United States 
 2011- Washington University, Saint Louis, St. Louis, MO 
Area:
vector development, gene therapy vaccine and virotherapy interventions.
Website:
http://ocf.wustl.edu/research/cancerbio/curiel/people.aspx
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Year Citation  Score
2023 Rice-Boucher PJ, Mendonça SA, Alvarez AB, Sturtz AJ, Lorincz R, Dmitriev IP, Kashentseva EA, Lu ZH, Romano R, Selby M, Pingale K, Curiel DT. Adenoviral vectors infect B lymphocytes in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 37452494 DOI: 10.1016/j.ymthe.2023.07.004  0.304
2022 Lorincz R, Alvarez AB, Walkey CJ, Mendonça SA, Lu ZH, Martinez AE, Ljungberg C, Heaney JD, Lagor WR, Curiel DT. In vivo editing of the pan-endothelium by immunity evading simian adenoviral vector. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 158: 114189. PMID 36587560 DOI: 10.1016/j.biopha.2022.114189  0.368
2022 Lu ZH, Li J, Dmitriev IP, Kashentseva EA, Curiel DT. Efficient Genome Editing Achieved via Plug-and-Play Adenovirus Piggyback Transport of Cas9/gRNA Complex on Viral Capsid Surface. Acs Nano. PMID 35749339 DOI: 10.1021/acsnano.2c00909  0.306
2021 Collins LT, Curiel DT. Synthetic Biology Approaches for Engineering Next-Generation Adenoviral Gene Therapies. Acs Nano. PMID 34415739 DOI: 10.1021/acsnano.1c04556  0.327
2021 Lee M, Lu ZH, Shoemaker CB, Tremblay JM, St Croix B, Seaman S, Gonzalez-Pastor R, Kashentseva EA, Dmitriev IP, Curiel DT. Advanced genetic engineering to achieve in vivo targeting of adenovirus utilizing camelid single domain antibody. Journal of Controlled Release : Official Journal of the Controlled Release Society. 334: 106-113. PMID 33872627 DOI: 10.1016/j.jconrel.2021.04.009  0.305
2020 Gonzalez-Pastor R, Goedegebuure PS, Curiel DT. Understanding and addressing barriers to successful adenovirus-based virotherapy for ovarian cancer. Cancer Gene Therapy. PMID 32951021 DOI: 10.1038/S41417-020-00227-Y  0.421
2020 Hassan AO, Kafai NM, Dmitriev IP, Fox JM, Smith BK, Harvey IB, Chen RE, Winkler ES, Wessel AW, Case JB, Kashentseva E, McCune BT, Bailey AL, Zhao H, VanBlargan LA, ... ... Curiel DT, et al. A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2. Cell. PMID 32931734 DOI: 10.1016/J.Cell.2020.08.026  0.316
2020 Boucher P, Cui X, Curiel DT. Adenoviral vectors for in vivo delivery of CRISPR-Cas gene editors. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 32891680 DOI: 10.1016/J.Jconrel.2020.09.003  0.384
2020 Lorincz R, Curiel DT. Advances in Alpha-1 Antitrypsin Gene Therapy. American Journal of Respiratory Cell and Molecular Biology. PMID 32668173 DOI: 10.1165/Rcmb.2020-0159Ps  0.401
2020 Mooney R, Majid AA, Batalla-Covello J, Machado D, Liu X, Gonzaga J, Tirughana R, Hammad M, Dellinger TH, Lesniak MS, Curiel DT, Aboody KS. Erratum: Enhanced Delivery of Oncolytic Adenovirus by Neural Stem Cells for Treatment of Metastatic Ovarian Cancer. Molecular Therapy Oncolytics. 17: 508. PMID 32577499 DOI: 10.1016/J.Omto.2020.05.005  0.33
2020 Lu ZH, Dmitriev IP, Brough DE, Kashentseva EA, Li J, Curiel DT. A new gorilla adenoviral vector with natural lung tropism avoids liver toxicity and is amenable for capsid engineering and vector retargeting. Journal of Virology. PMID 32102889 DOI: 10.1128/Jvi.00265-20  0.397
2020 Lee M, Lu ZH, Li J, Kashentseva EA, Dmitriev IP, Mendonca SA, Curiel DT. Targeting tumor neoangiogenesis via targeted adenoviral vector to achieve effective cancer gene therapy for disseminated neoplastic disease. Molecular Cancer Therapeutics. PMID 31907220 DOI: 10.1158/1535-7163.Mct-19-0768  0.487
2019 Broeckel RM, Haese N, Ando T, Dmitriev I, Kreklywich CN, Powers J, Denton M, Smith P, Morrison TE, Heise M, DeFilippis V, Messaoudi I, Curiel DT, Streblow DN. Vaccine-Induced Skewing of T Cell Responses Protects Against Chikungunya Virus Disease. Frontiers in Immunology. 10: 2563. PMID 31736977 DOI: 10.3389/Fimmu.2019.02563  0.312
2019 Hassan AO, Dmitriev IP, Kashentseva EA, Zhao H, Brough DE, Fremont DH, Curiel DT, Diamond MS. A Gorilla Adenovirus-Based Vaccine against Zika Virus Induces Durable Immunity and Confers Protection in Pregnancy. Cell Reports. 28: 2634-2646.e4. PMID 31484074 DOI: 10.1016/J.Celrep.2019.08.005  0.303
2019 Stephens CJ, Lauron EJ, Kashentseva E, Lu ZH, Yokoyama WM, Curiel DT. Long-term correction of hemophilia B using adenoviral delivery of CRISPR/Cas9. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30771412 DOI: 10.1016/J.Jconrel.2019.02.009  0.41
2019 González-Pastor R, Ashshi AM, El-Shemi AG, Dmitriev IP, Kashentseva EA, Lu ZH, Goedegebuure SP, Podhajcer OL, Curiel DT. Defining a murine ovarian cancer model for the evaluation of conditionally-replicative adenovirus (CRAd) virotherapy agents. Journal of Ovarian Research. 12: 18. PMID 30767772 DOI: 10.1186/S13048-019-0493-5  0.384
2019 Mooney R, Majid AA, Batalla-Covello J, Machado D, Liu X, Gonzaga J, Tirughana R, Hammad M, Lesniak MS, Curiel DT, Aboody KS. Enhanced Delivery of Oncolytic Adenovirus by Neural Stem Cells for Treatment of Metastatic Ovarian Cancer. Molecular Therapy Oncolytics. 12: 79-92. PMID 30719498 DOI: 10.1016/J.Omto.2018.12.003  0.436
2019 Stephens C, Kashentseva E, Lu Z, Curiel D. Achievement of long term gene expression via adenoviral vector-mediated delivery of CRISPR/Cas9 for in vivo editing and gene knock-in Cytotherapy. 21: S14-S15. DOI: 10.1016/J.Jcyt.2019.03.579  0.425
2018 van Winkel CA, Moreno A, Curiel DT. Capsid-incorporation strategy to display antigens for an alternative adenoviral vector vaccine approach. Molecular Pharmaceutics. PMID 30359030 DOI: 10.1021/Acs.Molpharmaceut.8B00591  0.35
2018 Chondronasiou D, Eisden TTHD, Stam AGM, Matthews QL, Icyuz M, Hooijberg E, Dmitriev I, Curiel DT, de Gruijl TD, van de Ven R. Improved Induction of Anti-Melanoma T Cells by Adenovirus-5/3 Fiber Modification to Target Human DCs. Vaccines. 6. PMID 30022005 DOI: 10.3390/Vaccines6030042  0.43
2018 Stephens CJ, Kashentseva E, Everett W, Kaliberova L, Curiel DT. Targeted in vivo knock-in of human alpha-1-antitrypsin cDNA using adenoviral delivery of CRISPR/Cas9. Gene Therapy. PMID 29588497 DOI: 10.1038/S41434-018-0003-1  0.404
2017 Kuroki LM, Jin X, Dmitriev IP, Kashentseva EA, Powell MA, Mutch DG, Dietz AB, Curiel DT, Hawkins WG, Spitzer D. Adenovirus platform enhances transduction efficiency of human mesenchymal stem cells: An opportunity for cellular carriers of targeted TRAIL-based TR3 biologics in ovarian cancer. Plos One. 12: e0190125. PMID 29267342 DOI: 10.1371/Journal.Pone.0190125  0.482
2017 Sharma PK, Dmitriev IP, Kashentseva EA, Raes G, Li L, Kim SW, Lu ZH, Arbeit JM, Fleming TP, Kaliberov SA, Goedegebuure SP, Curiel DT, Gillanders WE. Development of an adenovirus vector vaccine platform for targeting dendritic cells. Cancer Gene Therapy. PMID 29242639 DOI: 10.1038/S41417-017-0002-1  0.4
2017 Fonseca JA, McCaffery JN, Kashentseva E, Singh B, Dmitriev IP, Curiel DT, Moreno A. A prime-boost immunization regimen based on a simian adenovirus 36 vectored multi-stage malaria vaccine induces protective immunity in mice. Vaccine. PMID 28483199 DOI: 10.1016/J.Vaccine.2017.04.062  0.341
2017 Naoum GE, Zhu ZB, Buchsbaum DJ, Curiel DT, Arafat WO. Survivin a radiogenetic promoter for glioblastoma viral gene therapy independently from CArG motifs. Clinical and Translational Medicine. 6: 11. PMID 28251571 DOI: 10.1186/S40169-017-0140-Y  0.6
2017 Lu ZH, Kaliberov S, Sohn RE, Kaliberova L, Du Y, Prior JL, Leib DJ, Chauchereau A, Sehn JK, Curiel DT, Arbeit JM. A new model of multi-visceral and bone metastatic prostate cancer with perivascular niche targeting by a novel endothelial specific adenoviral vector. Oncotarget. PMID 28103576 DOI: 10.18632/Oncotarget.14699  0.422
2017 Prima V, Kaliberova LN, Kaliberov S, Curiel DT, Kusmartsev S. COX2/mPGES1/PGE2 pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28096371 DOI: 10.1073/Pnas.1612920114  0.32
2017 Lesniak MS, Stupp R, Sachdev S, Lukas R, Chandler J, Portnow J, Amidei C, Miska J, Balyasnikova I, Ahmed A, Curiel D, Strong T, LeFever A, Adams A, Giles F, et al. ACTR-36. A PHASE I STUDY OF NEURAL STEM CELLS LOADED WITH AN ONCOLYTIC ADENOVIRUS FOR PATIENTS WITH NEWLY DIAGNOSED MALIGNANT GLIOMA: PRELIMINARY SAFETY AND DATA ANALYSIS Neuro-Oncology. 19: vi8-vi8. DOI: 10.1093/Neuonc/Nox168.027  0.376
2017 Kuroki LM, Jin X, Dmitriev I, Powell MA, Mutch DG, Curiel DT, Hawkins W, Spitzer D. Adenovirus platform enhances transduction efficiency of human mesenchymal stem cells: An opportunity for cellular carriers of targeted TRAIL-based TR3 therapeutics in ovarian cancer Gynecologic Oncology. 145: 91. DOI: 10.1016/J.Ygyno.2017.03.213  0.39
2016 Bhatia S, O'Bryan SM, Rivera AA, Curiel DT, Mathis JM. CXCL12 retargeting of an adenovirus vector to cancer cells using a bispecific adapter. Oncolytic Virotherapy. 5: 99-113. PMID 27957479 DOI: 10.2147/OV.S112107  0.391
2016 Cabrera-Mora M, Fonseca JA, Singh B, Zhao C, Makarova N, Dmitriev I, Curiel DT, Blackwell J, Moreno A. A Recombinant Chimeric Ad5/3 Vector Expressing a Multistage Plasmodium Antigen Induces Protective Immunity in Mice Using Heterologous Prime-Boost Immunization Regimens. Journal of Immunology (Baltimore, Md. : 1950). PMID 27574299 DOI: 10.4049/Jimmunol.1501926  0.398
2016 Stroud C, Dmitriev I, Kashentseva E, Bryan JN, Curiel DT, Rindt H, Reinero C, Henry CJ, Bergman PJ, Mason NJ, Gnanandarajah JS, Engiles JB, Gray F, Laughlin D, Gaurnier-Hausser A, et al. A One Health overview, facilitating advances in comparative medicine and translational research. Clinical and Translational Medicine. 5: 26. PMID 27558513 DOI: 10.1186/S40169-016-0107-4  0.309
2016 Schmidt DJ, Beamer G, Tremblay JM, Steele JA, Kim HB, Wang Y, Debatis M, Sun X, Kashentseva EA, Dmitriev IP, Curiel DT, Shoemaker CB, Tzipori S. A Tetraspecific VHH-based Neutralizing Antibody Modifies Disease Outcome in Three Animal Models of Clostridium difficile Infection. Clinical and Vaccine Immunology : Cvi. PMID 27413067 DOI: 10.1128/Cvi.00730-15  0.325
2016 Ashshi AM, El-Shemi AG, Dmitriev IP, Kashentseva EA, Curiel DT. Combinatorial strategies based on CRAd-IL24 and CRAd-ING4 virotherapy with anti-angiogenesis treatment for ovarian cancer. Journal of Ovarian Research. 9: 38. PMID 27349517 DOI: 10.1186/S13048-016-0248-5  0.445
2016 Fonseca JA, Cabrera-Mora M, Kashentseva EA, Villegas JP, Fernandez A, Van Pelt A, Dmitriev IP, Curiel DT, Moreno A. A Plasmodium Promiscuous T Cell Epitope Delivered within the Ad5 Hexon Protein Enhances the Protective Efficacy of a Protein Based Malaria Vaccine. Plos One. 11: e0154819. PMID 27128437 DOI: 10.1371/Journal.Pone.0154819  0.34
2016 Tatzel K, Kuroki L, Dmitriev I, Kashentseva E, Curiel DT, Goedegebuure SP, Powell MA, Mutch DG, Hawkins WG, Spitzer D. Membrane-proximal TRAIL species are incapable of inducing short circuit apoptosis signaling: Implications for drug development and basic cytokine biology. Scientific Reports. 6: 22661. PMID 26935795 DOI: 10.1038/Srep22661  0.363
2016 Abdelaziz M, Sherif L, ElKhiary M, Nair S, Shalaby S, Mohamed S, Eziba N, El-Lakany M, Curiel D, Ismail N, Diamond MP, Al-Hendy A. Targeted Adenoviral Vector Demonstrates Enhanced Efficacy for In Vivo Gene Therapy of Uterine Leiomyoma. Reproductive Sciences (Thousand Oaks, Calif.). 23: 464-74. PMID 26884457 DOI: 10.1177/1933719116630413  0.47
2016 Othman ER, Curiel DT, Hussein M, Abdelaal II, Fetih AN, Al-Hendy A. Enhancing Adenoviral-Mediated Gene Transfer and Expression to Endometrial Cells. Reproductive Sciences (Thousand Oaks, Calif.). PMID 26865542 DOI: 10.1177/1933719116630420  0.478
2016 Buggio M, Towe C, Annan A, Kaliberov S, Lu ZH, Stephens C, Arbeit JM, Curiel DT. Pulmonary Vasculature Directed Adenovirus Increases Epithelial Lining Fluid Alpha-1 Antitrypsin Levels. The Journal of Gene Medicine. PMID 26825735 DOI: 10.1002/Jgm.2874  0.322
2016 Moayeri M, Tremblay JM, Debatis M, Dmietriev IP, Kashentseva EA, Yeh AJ, Cheung GY, Curiel DT, Leppla S, Shoemaker CB. Adenoviral expression of a bispecific VHH-based neutralizing agent targeting protective antigen provides prophylactic protection from anthrax in mice. Clinical and Vaccine Immunology : Cvi. PMID 26740390 DOI: 10.1128/Cvi.00611-15  0.36
2016 Abdelaziz M, Sherif L, Elkhiary M, Nair S, Shalaby S, Mohamed S, Eziba N, El-Lakany M, Curiel D, Ismail N, Diamond MP, Al-Hendy A. Targeted Adenoviral Vector Demonstrates Enhanced Efficacy for in Vivo Gene Therapy of Uterine Leiomyoma Reproductive Sciences. 23: 464-474. DOI: 10.1177/1933719116630413  0.303
2016 Huang JL, LaRocca C, Jacobsen K, Kaliberov S, Curiel DT, Davydova J, Yamamoto M. 519. Intravenous Application of CXCR4 Targeted Conditionally Replicative Adenovirus with Fiber and Hexon Modifications to Pancreatic Cancer Molecular Therapy. 24: S207. DOI: 10.1016/S1525-0016(16)33328-7  0.455
2016 Smith BF, Agarwal P, Gammon E, Curiel DT, Dmitriev I, Kashentseva E. 517. Anti-Tumor Immunity Is Elicited by a Conditionally Replicative Adenovirus in Canine Osteosarcoma Molecular Therapy. 24: S206. DOI: 10.1016/S1525-0016(16)33326-3  0.379
2016 Huang J, LaRocca C, Jacobsen K, Karyverov S, Curiel DT, Davydova J, Yamamoto M. Intravenous application of CXCR4-targeted conditionally replicative adenovirus with fiber and hexon modifications to pancreatic cancer Pancreatology. 16: S43-S44. DOI: 10.1016/J.Pan.2016.06.165  0.349
2015 van Erp EA, Kaliberova LN, Kaliberov SA, Curiel DT. Retargeted oncolytic adenovirus displaying a single variable domain of camelid heavy-chain-only antibody in a fiber protein. Molecular Therapy Oncolytics. 2: 15001. PMID 27119101 DOI: 10.1038/Mto.2015.1  0.393
2015 Dobbins GC, Ugai H, Curiel DT, Gillespie GY. A Multi Targeting Conditionally Replicating Adenovirus Displays Enhanced Oncolysis while Maintaining Expression of Immunotherapeutic Agents. Plos One. 10: e0145272. PMID 26689910 DOI: 10.1371/Journal.Pone.0145272  0.624
2015 Kim JW, Kane JR, Young JS, Chang A, Kanojia D, Morshed R, Miska J, Ahmed A, Balyasnikova I, Han Y, Zhang L, Curiel D, Lesniak MS. A Genetically Modified Adenoviral Vector with a Phage Display Derived Peptide Incorporated into Fiber Fibritin Chimera Prolongs Survival in Experimental Glioma. Human Gene Therapy. PMID 26058317 DOI: 10.1089/Hum.2015.008  0.416
2015 Wilkinson-Ryan I, Kim J, Kim S, Ak F, Dodson L, Colonna M, Powell M, Mutch D, Spitzer D, Hansen T, Goedegebuure SP, Curiel D, Hawkins W. Incorporation of porcine adenovirus 4 fiber protein enhances infectivity of adenovirus vector on dendritic cells: implications for immune-mediated cancer therapy. Plos One. 10: e0125851. PMID 25933160 DOI: 10.1371/Journal.Pone.0125851  0.502
2015 Beatty MS, Timares L, Curiel DT. Augmented adenovirus transduction of murine T lymphocytes utilizing a bi-specific protein targeting murine interleukin 2 receptor. Cancer Gene Therapy. 22: 222. PMID 25904493 DOI: 10.1038/cgt.2015.13  0.708
2015 Everett WH, Curiel DT. Gene therapy for radioprotection. Cancer Gene Therapy. 22: 172-80. PMID 25721205 DOI: 10.1038/Cgt.2015.8  0.351
2015 Weber HL, Gidekel M, Werbajh S, Salvatierra E, Rotondaro C, Sganga L, Haab GA, Curiel DT, Cafferata EG, Podhajcer OL. A Novel CDC25B Promoter-Based Oncolytic Adenovirus Inhibited Growth of Orthotopic Human Pancreatic Tumors in Different Preclinical Models. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1665-74. PMID 25573380 DOI: 10.1158/1078-0432.Ccr-14-2316  0.365
2015 Sheoran AS, Dmitriev IP, Kashentseva EA, Cohen O, Mukherjee J, Debatis M, Shearer J, Tremblay JM, Beamer G, Curiel DT, Shoemaker CB, Tzipori S. Adenovirus vector expressing Stx1/Stx2-neutralizing agent protects piglets infected with Escherichia coli O157:H7 against fatal systemic intoxication. Infection and Immunity. 83: 286-91. PMID 25368111 DOI: 10.1128/Iai.02360-14  0.35
2015 Lu ZH, Kaliberov S, Kaliberova L, Sohn RE, Du Y, Curiel DT, Arbeit JM. Abstract 5210: Creation of endothelial-targeted adenoviral vectors for genetic engineering of the metastatic tumor microenvironment Cancer Research. 75: 5210-5210. DOI: 10.1158/1538-7445.Am2015-5210  0.48
2015 Muhoro L, Yan H, Kaliberov S, Jaboin J, Curiel D, Hallahan D. Abstract 4376: Characterization and targeting of TAF15, a radiation-inducible target in multiple cancer types Cancer Research. 75: 4376-4376. DOI: 10.1158/1538-7445.Am2015-4376  0.434
2015 van Erp E, Kaliberova L, Kaliberov S, Thomas E, Bevis K, Alvarez R, Curiel D. Utilizing camelid-derived single domain antibodies to enhance immunotherapy of ovarian cancer Gynecologic Oncology. 137: 133. DOI: 10.1016/J.Ygyno.2015.01.331  0.349
2015 Kuroki L, Dmitriev I, Gibbs J, Tatzel K, Powell M, Mutch D, Dietz A, Curiel D, Hawkins W, Spitzer D. Cell-based therapy in ovarian cancer: Improved adenoviral transduction strategy of human mesenchymal stem cells as tumor-homing drug factories Gynecologic Oncology. 137: 64. DOI: 10.1016/J.Ygyno.2015.01.150  0.394
2014 Dmitriev IP, Kashentseva EA, Kim KH, Matthews QL, Krieger SS, Parry JJ, Nguyen KN, Akers WJ, Achilefu S, Rogers BE, Alvarez RD, Curiel DT. Monitoring of biodistribution and persistence of conditionally replicative adenovirus in a murine model of ovarian cancer using capsid-incorporated mCherry and expression of human somatostatin receptor subtype 2 gene. Molecular Imaging. 13. PMID 25249483 DOI: 10.2310/7290.2014.00024  0.406
2014 Kawamura YI, Adachi Y, Curiel DT, Kawashima R, Kannagi R, Nishimoto N, Dohi T. Therapeutic adenoviral gene transfer of a glycosyltransferase for prevention of peritoneal dissemination and metastasis of gastric cancer. Cancer Gene Therapy. 21: 427-33. PMID 25213663 DOI: 10.1038/Cgt.2014.46  0.458
2014 Lewis TB, Glasgow JN, Harms AS, Standaert DG, Curiel DT. Fiber-modified adenovirus for central nervous system Parkinson's disease gene therapy. Viruses. 6: 3293-310. PMID 25196484 DOI: 10.3390/V6083293  0.446
2014 Mukherjee J, Dmitriev I, Debatis M, Tremblay JM, Beamer G, Kashentseva EA, Curiel DT, Shoemaker CB. Prolonged prophylactic protection from botulism with a single adenovirus treatment promoting serum expression of a VHH-based antitoxin protein. Plos One. 9: e106422. PMID 25170904 DOI: 10.1371/Journal.Pone.0106422  0.345
2014 Alqahtani A, Heesom K, Bramson JL, Curiel D, Ugai H, Matthews DA. Analysis of purified wild type and mutant adenovirus particles by SILAC based quantitative proteomics. The Journal of General Virology. 95: 2504-11. PMID 25096814 DOI: 10.1099/Vir.0.068221-0  0.318
2014 Liu L, Rogers BE, Aladyshkina N, Cheng B, Lokitz SJ, Curiel DT, Mathis JM. Construction and radiolabeling of adenovirus variants that incorporate human metallothionein into protein IX for analysis of biodistribution. Molecular Imaging. 13. PMID 25060486 DOI: 10.2310/7290.2014.00022  0.376
2014 Lu ZH, Kaliberov S, Zhang J, Muz B, Azab AK, Sohn RE, Kaliberova L, Du Y, Curiel DT, Arbeit JM. The myeloid-binding peptide adenoviral vector enables multi-organ vascular endothelial gene targeting. Laboratory Investigation; a Journal of Technical Methods and Pathology. 94: 881-92. PMID 24955893 DOI: 10.1038/Labinvest.2014.78  0.464
2014 Kaliberov SA, Kaliberova LN, Buggio M, Tremblay JM, Shoemaker CB, Curiel DT. Adenoviral targeting using genetically incorporated camelid single variable domains. Laboratory Investigation; a Journal of Technical Methods and Pathology. 94: 893-905. PMID 24933423 DOI: 10.1038/Labinvest.2014.82  0.474
2014 Kaliberov SA, Kaliberova LN, Buchsbaum DJ, Curiel DT. Experimental virotherapy of chemoresistant pancreatic carcinoma using infectivity-enhanced fiber-mosaic oncolytic adenovirus. Cancer Gene Therapy. 21: 264-74. PMID 24903014 DOI: 10.1038/Cgt.2014.26  0.625
2014 Sandey M, Bird RC, Das SK, Sarkar D, Curiel DT, Fisher PB, Smith BF. Characterization of the canine mda-7 gene, transcripts and expression patterns. Gene. 547: 23-33. PMID 24865935 DOI: 10.1016/J.Gene.2014.05.054  0.339
2014 Uchino J, Curiel DT, Ugai H. Species D human adenovirus type 9 exhibits better virus-spread ability for antitumor efficacy among alternative serotypes. Plos One. 9: e87342. PMID 24503714 DOI: 10.1371/Journal.Pone.0087342  0.464
2014 Curiel DT. Methods for Gene Transfer Using DNA-Adenovirus Conjugates. Methods in Molecular Medicine. 7: 1-23. PMID 24493415 DOI: 10.1385/0-89603-484-4:1  0.355
2014 Azab BM, Dash R, Das SK, Bhutia SK, Sarkar S, Shen XN, Quinn BA, Dent P, Dmitriev IP, Wang XY, Curiel DT, Pellecchia M, Reed JC, Sarkar D, Fisher PB. Enhanced prostate cancer gene transfer and therapy using a novel serotype chimera cancer terminator virus (Ad.5/3-CTV). Journal of Cellular Physiology. 229: 34-43. PMID 23868767 DOI: 10.1002/Jcp.24408  0.484
2014 Kaliberov SA, Kaliberova LN, Buchsbaum DJ, Curiel DT. Experimental virotherapy of chemoresistant pancreatic carcinoma using infectivity-enhanced fiber-mosaic oncolytic adenovirus Cancer Gene Therapy. 21: 264-274. DOI: 10.1038/cgt.2014.26  0.578
2014 Wilkinson-Ryan I, Kim J, Kim S, Powell M, Mutch D, Spitzer D, Hansen T, Goedebeuure S, Curiel D, Hawkins W. Incorporation of porcine adenovirus 4 fiber protein enhances infectivity of adenovirus vector on dendritic cells: Implications for immune-mediated cancer therapy Gynecologic Oncology. 133: 104-105. DOI: 10.1016/J.Ygyno.2014.03.278  0.407
2013 Lu ZH, Kaliberov S, Sohn RE, Kaliberova L, Curiel DT, Arbeit JM. Transcriptional targeting of primary and metastatic tumor neovasculature by an adenoviral type 5 roundabout4 vector in mice. Plos One. 8: e83933. PMID 24376772 DOI: 10.1371/Journal.Pone.0083933  0.458
2013 Kaliberov SA, Kaliberova LN, Hong Lu Z, Preuss MA, Barnes JA, Stockard CR, Grizzle WE, Arbeit JM, Curiel DT. Retargeting of gene expression using endothelium specific hexon modified adenoviral vector. Virology. 447: 312-25. PMID 24210128 DOI: 10.1016/J.Virol.2013.09.020  0.458
2013 Beatty MS, Timares L, Curiel DT. Augmented adenovirus transduction of murine T lymphocytes utilizing a bi-specific protein targeting murine interleukin 2 receptor. Cancer Gene Therapy. 20: 445-52. PMID 23928733 DOI: 10.1038/Cgt.2013.39  0.74
2013 Nair S, Saed GM, Atta HM, Rajaratnam V, Diamond MP, Curiel DT, Al-Hendy A. Towards gene therapy of postoperative adhesions: fiber and transcriptional modifications enhance adenovirus targeting towards human adhesion cells. Gynecologic and Obstetric Investigation. 76: 119-24. PMID 23920223 DOI: 10.1159/000353426  0.312
2013 Nair S, Curiel DT, Rajaratnam V, Thota C, Al-Hendy A. Targeting adenoviral vectors for enhanced gene therapy of uterine leiomyomas Human Reproduction. 28: 2398-2406. PMID 23820419 DOI: 10.1093/Humrep/Det275  0.488
2013 Kim KH, Dmitriev IP, Saddekni S, Kashentseva EA, Harris RD, Aurigemma R, Bae S, Singh KP, Siegal GP, Curiel DT, Alvarez RD. A phase I clinical trial of Ad5/3-Δ24, a novel serotype-chimeric, infectivity-enhanced, conditionally-replicative adenovirus (CRAd), in patients with recurrent ovarian cancer. Gynecologic Oncology. 130: 518-24. PMID 23756180 DOI: 10.1016/J.Ygyno.2013.06.003  0.407
2013 Viale DL, Cafferata EG, Gould D, Rotondaro C, Chernajovsky Y, Curiel DT, Podhajcer OL, Lopez MV. Therapeutic improvement of a stroma-targeted CRAd by incorporating motives responsive to the melanoma microenvironment. The Journal of Investigative Dermatology. 133: 2576-84. PMID 23604101 DOI: 10.1038/Jid.2013.191  0.446
2013 Kim JW, Glasgow JN, Nakayama M, Ak F, Ugai H, Curiel DT. An adenovirus vector incorporating carbohydrate binding domains utilizes glycans for gene transfer. Plos One. 8: e55533. PMID 23383334 DOI: 10.1371/Journal.Pone.0055533  0.504
2013 Chen D, Siddiq A, Emdad L, Rajasekaran D, Gredler R, Shen XN, Santhekadur PK, Srivastava J, Robertson CL, Dmitriev I, Kashentseva EA, Curiel DT, Fisher PB, Sarkar D. Insulin-like growth factor-binding protein-7 (IGFBP7): a promising gene therapeutic for hepatocellular carcinoma (HCC). Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 758-66. PMID 23319057 DOI: 10.1038/Mt.2012.282  0.351
2013 Alberti MO, Deshane JS, Chaplin DD, Pereboeva L, Curiel DT, Roth JC. A myeloid cell-binding adenovirus efficiently targets gene transfer to the lung and escapes liver tropism. Gene Therapy. 20: 733-41. PMID 23171918 DOI: 10.1038/Gt.2012.91  0.432
2013 Nair S, Curiel D, Sharan C, Al-Hendy A. Towards uterine fibroids gene therapy: fibroid-targeted adenovirus (AD-SSTR-RGD-TK/GCV) demonstrates enhanced inhibition of tumor growth in nude mice Fertility and Sterility. 100: S147. DOI: 10.1016/J.Fertnstert.2013.07.1549  0.438
2013 Mahalingam D, Brumlik MJ, Waehler R, Curiel DT, Curiel TJ. Targeted toxins in cancer immunotherapy Cancer Immunotherapy: Paradigms, Practice and Promise. 2147483647: 377-396. DOI: 10.1007/978-1-4614-4732-0_12  0.361
2012 Flatt JW, Fox TL, Makarova N, Blackwell JL, Dmitriev IP, Kashentseva EA, Curiel DT, Stewart PL. CryoEM visualization of an adenovirus capsid-incorporated HIV antigen. Plos One. 7: e49607. PMID 23166728 DOI: 10.1371/Journal.Pone.0049607  0.344
2012 Williams BJ, Bhatia S, Adams LK, Boling S, Carroll JL, Li XL, Rogers DL, Korokhov N, Kovesdi I, Pereboev AV, Curiel DT, Mathis JM. Dendritic cell based PSMA immunotherapy for prostate cancer using a CD40-targeted adenovirus vector. Plos One. 7: e46981. PMID 23056548 DOI: 10.1371/Journal.Pone.0046981  0.463
2012 Beatty MS, Curiel DT. Chapter two--Adenovirus strategies for tissue-specific targeting. Advances in Cancer Research. 115: 39-67. PMID 23021241 DOI: 10.1016/B978-0-12-398342-8.00002-1  0.764
2012 Lopez MV, Rivera AA, Viale DL, Benedetti L, Cuneo N, Kimball KJ, Wang M, Douglas JT, Zhu ZB, Bravo AI, Gidekel M, Alvarez RD, Curiel DT, Podhajcer OL. A tumor-stroma targeted oncolytic adenovirus replicated in human ovary cancer samples and inhibited growth of disseminated solid tumors in mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 2222-33. PMID 22948673 DOI: 10.1038/Mt.2012.147  0.447
2012 Chu QD, Sun G, Pope M, Luraguiz N, Curiel DT, Kim R, Li BD, Mathis JM. Virotherapy using a novel chimeric oncolytic adenovirus prolongs survival in a human pancreatic cancer xenograft model. Surgery. 152: 441-8. PMID 22853858 DOI: 10.1016/J.Surg.2012.05.040  0.468
2012 Ugai H, Dobbins GC, Wang M, Le LP, Matthews DA, Curiel DT. Adenoviral protein V promotes a process of viral assembly through nucleophosmin 1. Virology. 432: 283-95. PMID 22717133 DOI: 10.1016/J.Virol.2012.05.028  0.413
2012 Alberti MO, Roth JC, Ismail M, Tsuruta Y, Abraham E, Pereboeva L, Gerson SL, Curiel DT. Derivation of a myeloid cell-binding adenovirus for gene therapy of inflammation. Plos One. 7: e37812. PMID 22624065 DOI: 10.1371/Journal.Pone.0037812  0.507
2012 Kim KH, Dmitriev I, O'Malley JP, Wang M, Saddekni S, You Z, Preuss MA, Harris RD, Aurigemma R, Siegal GP, Zinn KR, Curiel DT, Alvarez RD. A phase I clinical trial of Ad5.SSTR/TK.RGD, a novel infectivity-enhanced bicistronic adenovirus, in patients with recurrent gynecologic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3440-51. PMID 22510347 DOI: 10.1158/1078-0432.Ccr-11-2852  0.445
2012 Hangalapura BN, Timares L, Oosterhoff D, Scheper RJ, Curiel DT, de Gruijl TD. CD40-targeted adenoviral cancer vaccines: the long and winding road to the clinic. The Journal of Gene Medicine. 14: 416-27. PMID 22228547 DOI: 10.1002/Jgm.1648  0.413
2012 Azab B, Dash R, Das SK, Bhutia SK, Shen XN, Quinn BA, Sarkar S, Wang XY, Hedvat M, Dmitriev IP, Curiel DT, Grant S, Dent P, Reed JC, Pellecchia M, et al. Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells. Journal of Cellular Physiology. 227: 2145-53. PMID 21780116 DOI: 10.1002/Jcp.22947  0.484
2012 Bhutia SK, Das SK, Kegelman TP, Azab B, Dash R, Su ZZ, Wang XY, Rizzi F, Bettuzzi S, Lee SG, Dent P, Grant S, Curiel DT, Sarkar D, Fisher PB. mda-7/IL-24 differentially regulates soluble and nuclear clusterin in prostate cancer. Journal of Cellular Physiology. 227: 1805-13. PMID 21732348 DOI: 10.1002/Jcp.22904  0.398
2012 Bilbao G, Gomez-Navarro J, Kazano K, Luis Contreras J, Curiel DT. 9 intracellular single-chain antibodies for gene therapy. Methods in Molecular Medicine. 35: 121-49. PMID 21390804 DOI: 10.1385/1-59259-086-1:121  0.393
2012 Azab B, Dash R, Das S, Bhutia S, Shen X, Quinn B, Dasgupta S, Dent P, Dmitriev I, Wang X, Curiel D, Grant S, Pellecchia M, Reed J, Sarkar D, et al. Abstract 61: A new serotype chimera Cancer Terminator Virus (Ad.5/3-CTV) expands the efficiency and specificity of prostate cancer gene transfer and therapy Cancer Research. 72: 61-61. DOI: 10.1158/1538-7445.Am2012-61  0.483
2011 Quinn BA, Dash R, Azab B, Sarkar S, Das SK, Kumar S, Oyesanya RA, Dasgupta S, Dent P, Grant S, Rahmani M, Curiel DT, Dmitriev I, Hedvat M, Wei J, et al. Targeting Mcl-1 for the therapy of cancer. Expert Opinion On Investigational Drugs. 20: 1397-411. PMID 21851287 DOI: 10.1517/13543784.2011.609167  0.402
2011 Hangalapura BN, Oosterhoff D, de Groot J, Boon L, Tüting T, van den Eertwegh AJ, Gerritsen WR, van Beusechem VW, Pereboev A, Curiel DT, Scheper RJ, de Gruijl TD. Potent antitumor immunity generated by a CD40-targeted adenoviral vaccine. Cancer Research. 71: 5827-37. PMID 21747119 DOI: 10.1158/0008-5472.Can-11-0804  0.407
2011 Rein DT, Volkmer A, Beyer IM, Curiel DT, Janni W, Dragoi A, Hess AP, Maass N, Baldus SE, Bauerschmitz G, Breidenbach M. Treatment of chemotherapy resistant ovarian cancer with a MDR1 targeted oncolytic adenovirus. Gynecologic Oncology. 123: 138-46. PMID 21741695 DOI: 10.1016/J.Ygyno.2011.06.007  0.407
2011 Dent P, Curiel DT, Fisher PB. The potential of virus-based gene therapies for treatment of metastatic kidney cancer. Expert Review of Anticancer Therapy. 11: 809-11. PMID 21707273 DOI: 10.1586/Era.11.59  0.39
2011 Bhutia SK, Das SK, Azab B, Dash R, Su ZZ, Lee SG, Dent P, Curiel DT, Sarkar D, Fisher PB. Autophagy switches to apoptosis in prostate cancer cells infected with melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24). Autophagy. 7: 1076-7. PMID 21610321 DOI: 10.4161/Auto.7.9.16163  0.357
2011 Dash R, Azab B, Quinn BA, Shen X, Wang XY, Das SK, Rahmani M, Wei J, Hedvat M, Dent P, Dmitriev IP, Curiel DT, Grant S, Wu B, Stebbins JL, et al. Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity. Proceedings of the National Academy of Sciences of the United States of America. 108: 8785-90. PMID 21555592 DOI: 10.1073/Pnas.1100769108  0.338
2011 Mathis JM, Bhatia S, Khandelwal A, Kovesdi I, Lokitz SJ, Odaka Y, Takalkar AM, Terry T, Curiel DT. Genetic incorporation of human metallothionein into the adenovirus protein IX for non-invasive SPECT imaging. Plos One. 6: e16792. PMID 21347423 DOI: 10.1371/Journal.Pone.0016792  0.435
2011 O'Neill AM, Smith AN, Spangler EA, Whitley EM, Schleis SE, Bird RC, Curiel DT, Thacker EE, Smith BF. Resistance of canine lymphoma cells to adenoviral infection due to reduced cell surface RGD binding integrins. Cancer Biology & Therapy. 11: 651-8. PMID 21321486 DOI: 10.4161/Cbt.11.7.14690  0.468
2011 Dash R, Azab B, Shen XN, Sokhi UK, Sarkar S, Su ZZ, Wang XY, Claudio PP, Dent P, Dmitriev IP, Curiel DT, Grant S, Sarkar D, Fisher PB. Developing an effective gene therapy for prostate cancer: New technologies with potential to translate from the laboratory into the clinic. Discovery Medicine. 11: 46-56. PMID 21276410  0.391
2011 Hangalapura BN, Oosterhoff D, Gupta T, de Groot J, Wijnands PG, van Beusechem VW, den Haan J, Tüting T, van den Eertwegh AJ, Curiel DT, Scheper RJ, de Gruijl TD. Delivery route, MyD88 signaling and cross-priming events determine the anti-tumor efficacy of an adenovirus based melanoma vaccine. Vaccine. 29: 2313-21. PMID 21272606 DOI: 10.1016/J.Vaccine.2011.01.022  0.342
2011 Kim KH, Ryan MJ, Estep JE, Miniard BM, Rudge TL, Peggins JO, Broadt TL, Wang M, Preuss MA, Siegal GP, Hemminki A, Harris RD, Aurigemma R, Curiel DT, Alvarez RD. A new generation of serotype chimeric infectivity-enhanced conditionally replicative adenovirals: the safety profile of ad5/3-Δ24 in advance of a phase I clinical trial in ovarian cancer patients. Human Gene Therapy. 22: 821-8. PMID 21171861 DOI: 10.1089/Hum.2010.180  0.404
2011 Park MA, Hamed HA, Mitchell C, Cruickshanks N, Dash R, Allegood J, Dmitriev IP, Tye G, Ogretmen B, Spiegel S, Yacoub A, Grant S, Curiel DT, Fisher PB, Dent P. A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels. Molecular Pharmacology. 79: 368-80. PMID 21119025 DOI: 10.1124/Mol.110.069484  0.393
2011 Kim K, Wang M, Barnes M, O'Malley J, You Z, Preuss M, Siegal G, Zinn K, Curiel D, Alvarez R. A phase I clinical trial of a novel infectivity-enhanced suicide gene adenovirus with gene transfer imaging capacity in patients with recurrent gynecologic cancer Gynecologic Oncology. 120: S31. DOI: 10.1016/J.Ygyno.2010.12.077  0.354
2010 Kimball KJ, Preuss MA, Barnes MN, Wang M, Siegal GP, Wan W, Kuo H, Saddekni S, Stockard CR, Grizzle WE, Harris RD, Aurigemma R, Curiel DT, Alvarez RD. A phase I study of a tropism-modified conditionally replicative adenovirus for recurrent malignant gynecologic diseases. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 5277-87. PMID 20978148 DOI: 10.1158/1078-0432.Ccr-10-0791  0.34
2010 Eulitt PJ, Park MA, Hossein H, Cruikshanks N, Yang C, Dmitriev IP, Yacoub A, Curiel DT, Fisher PB, Dent P. Enhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene delivery. Cancer Biology & Therapy. 10: 1290-305. PMID 20948318 DOI: 10.4161/Cbt.10.12.13497  0.436
2010 Dash R, Bhutia SK, Azab B, Su ZZ, Quinn BA, Kegelmen TP, Das SK, Kim K, Lee SG, Park MA, Yacoub A, Rahmani M, Emdad L, Dmitriev IP, Wang XY, ... ... Curiel DT, et al. mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity. Cytokine & Growth Factor Reviews. 21: 381-91. PMID 20926331 DOI: 10.1016/J.Cytogfr.2010.08.004  0.388
2010 Lewis TB, Glasgow JN, Glandon AM, Curiel DT, Standaert DG. Transduction of brain dopamine neurons by adenoviral vectors is modulated by CAR expression: rationale for tropism modified vectors in PD gene therapy. Plos One. 5. PMID 20862245 DOI: 10.1371/Journal.Pone.0012672  0.428
2010 Murakami M, Ugai H, Wang M, Belousova N, Dent P, Fisher PB, Glasgow JN, Everts M, Curiel DT. An adenoviral vector expressing human adenovirus 5 and 3 fiber proteins for targeting heterogeneous cell populations. Virology. 407: 196-205. PMID 20828776 DOI: 10.1016/J.Virol.2010.08.010  0.648
2010 Short JJ, Rivera AA, Wu H, Walter MR, Yamamoto M, Mathis JM, Curiel DT. Substitution of adenovirus serotype 3 hexon onto a serotype 5 oncolytic adenovirus reduces factor X binding, decreases liver tropism, and improves antitumor efficacy. Molecular Cancer Therapeutics. 9: 2536-44. PMID 20736345 DOI: 10.1158/1535-7163.Mct-10-0332  0.803
2010 Dent P, Yacoub A, Hamed HA, Park MA, Dash R, Bhutia SK, Sarkar D, Wang XY, Gupta P, Emdad L, Lebedeva IV, Sauane M, Su ZZ, Rahmani M, Broaddus WC, ... ... Curiel DT, et al. The development of MDA-7/IL-24 as a cancer therapeutic. Pharmacology & Therapeutics. 128: 375-84. PMID 20732354 DOI: 10.1016/J.Pharmthera.2010.08.001  0.357
2010 Pennington K, Chu QD, Curiel DT, Li BD, Mathis JM. The utility of a tissue slice model system to determine breast cancer infectivity by oncolytic adenoviruses. The Journal of Surgical Research. 163: 270-5. PMID 20691986 DOI: 10.1016/J.Jss.2010.03.072  0.378
2010 Matthews QL, Fatima A, Tang Y, Perry BA, Tsuruta Y, Komarova S, Timares L, Zhao C, Makarova N, Borovjagin AV, Stewart PL, Wu H, Blackwell JL, Curiel DT. HIV antigen incorporation within adenovirus hexon hypervariable 2 for a novel HIV vaccine approach. Plos One. 5: e11815. PMID 20676400 DOI: 10.1371/Journal.Pone.0011815  0.707
2010 Hangalapura BN, Oosterhoff D, Aggarwal S, Wijnands PG, van de Ven R, Santegoets SJ, van den Tol MP, Hooijberg E, Pereboev A, van den Eertwegh AJ, Curiel DT, Scheper RJ, de Gruijl TD. Selective transduction of dendritic cells in human lymph nodes and superior induction of high-avidity melanoma-reactive cytotoxic T cells by a CD40-targeted adenovirus. Journal of Immunotherapy (Hagerstown, Md. : 1997). 33: 706-15. PMID 20664356 DOI: 10.1097/Cji.0B013E3181Eccbd4  0.387
2010 Dent P, Yacoub A, Hamed HA, Park MA, Dash R, Bhutia SK, Sarkar D, Gupta P, Emdad L, Lebedeva IV, Sauane M, Su ZZ, Rahmani M, Broaddus WC, Young HF, ... ... Curiel DT, et al. MDA-7/IL-24 as a cancer therapeutic: from bench to bedside. Anti-Cancer Drugs. 21: 725-31. PMID 20613485 DOI: 10.1097/Cad.0B013E32833Cfbe1  0.345
2010 Paupoo AAV, Zhu ZB, Wang M, Rein DT, Starzinski-Powitz A, Curiel DT. A conditionally replicative adenovirus, CRAd-S-pK7, can target endometriosis with a cell-killing effect Human Reproduction. 25: 2068-2083. PMID 20573677 DOI: 10.1093/Humrep/Deq137  0.434
2010 Dash R, Richards JE, Su ZZ, Bhutia SK, Azab B, Rahmani M, Dasmahapatra G, Yacoub A, Dent P, Dmitriev IP, Curiel DT, Grant S, Pellecchia M, Reed JC, Sarkar D, et al. Mechanism by which Mcl-1 regulates cancer-specific apoptosis triggered by mda-7/IL-24, an IL-10-related cytokine. Cancer Research. 70: 5034-45. PMID 20501829 DOI: 10.1158/0008-5472.Can-10-0563  0.307
2010 Komarova S, Roth J, Alvarez R, Curiel DT, Pereboeva L. Targeting of mesenchymal stem cells to ovarian tumors via an artificial receptor. Journal of Ovarian Research. 3: 12. PMID 20500878 DOI: 10.1186/1757-2215-3-12  0.373
2010 Bhutia SK, Dash R, Das SK, Azab B, Su ZZ, Lee SG, Grant S, Yacoub A, Dent P, Curiel DT, Sarkar D, Fisher PB. Mechanism of autophagy to apoptosis switch triggered in prostate cancer cells by antitumor cytokine melanoma differentiation-associated gene 7/interleukin-24. Cancer Research. 70: 3667-76. PMID 20406981 DOI: 10.1158/0008-5472.Can-09-3647  0.393
2010 Borovjagin AV, McNally LR, Wang M, Curiel DT, MacDougall MJ, Zinn KR. Noninvasive monitoring of mRFP1- and mCherry-labeled oncolytic adenoviruses in an orthotopic breast cancer model by spectral imaging. Molecular Imaging. 9: 59-75. PMID 20236604 DOI: 10.2310/7290.2010.00003  0.365
2010 Hamed HA, Yacoub A, Park MA, Eulitt PJ, Dash R, Sarkar D, Dmitriev IP, Lesniak MS, Shah K, Grant S, Curiel DT, Fisher PB, Dent P. Inhibition of multiple protective signaling pathways and Ad.5/3 delivery enhances mda-7/IL-24 therapy of malignant glioma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1130-42. PMID 20179672 DOI: 10.1038/Mt.2010.29  0.433
2010 Dash R, Dmitriev I, Su ZZ, Bhutia SK, Azab B, Vozhilla N, Yacoub A, Dent P, Curiel DT, Sarkar D, Fisher PB. Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells Cancer Gene Therapy. 17: 447-456. PMID 20150932 DOI: 10.1038/cgt.2009.91  0.385
2010 Hamed HA, Yacoub A, Park MA, Eulitt P, Sarkar D, Dimitrie IP, Chen CS, Grant S, Curiel DT, Fisher PB, Dent P. OSU-03012 enhances Ad.7-induced GBM cell killing via ER stress and autophagy and by decreasing expression of mitochondrial protective proteins. Cancer Biology & Therapy. 9: 526-36. PMID 20107314 DOI: 10.4161/Cbt.9.7.11116  0.383
2010 Yacoub A, Hamed HA, Allegood J, Mitchell C, Spiegel S, Lesniak MS, Ogretmen B, Dash R, Sarkar D, Broaddus WC, Grant S, Curiel DT, Fisher PB, Dent P. PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells. Cancer Research. 70: 1120-9. PMID 20103619 DOI: 10.1158/0008-5472.Can-09-4043  0.408
2010 Li J, Fatima A, Komarova S, Ugai H, Uprety P, Roth JC, Wang M, Oster RA, Curiel DT, Matthews QL. Evaluation of adenovirus capsid labeling versus transgene expression. Virology Journal. 7: 21. PMID 20102632 DOI: 10.1186/1743-422X-7-21  0.396
2010 Yamamoto M, Curiel DT. Current issues and future directions of oncolytic adenoviruses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 243-50. PMID 19935777 DOI: 10.1038/Mt.2009.266  0.412
2010 Murakami M, Ugai H, Belousova N, Pereboev A, Dent P, Fisher PB, Everts M, Curiel DT. Chimeric adenoviral vectors incorporating a fiber of human adenovirus 3 efficiently mediate gene transfer into prostate cancer cells. The Prostate. 70: 362-76. PMID 19902467 DOI: 10.1002/Pros.21070  0.671
2010 Davydova J, Gavrikova T, Brown EJ, Luo X, Curiel DT, Vickers SM, Yamamoto M. In vivo bioimaging tracks conditionally replicative adenoviral replication and provides an early indication of viral antitumor efficacy. Cancer Science. 101: 474-81. PMID 19900190 DOI: 10.1111/J.1349-7006.2009.01407.X  0.37
2010 Greco A, Di Benedetto A, Howard CM, Kelly S, Nande R, Dementieva Y, Miranda M, Brunetti A, Salvatore M, Claudio L, Sarkar D, Dent P, Curiel DT, Fisher PB, Claudio PP. Eradication of therapy-resistant human prostate tumors using an ultrasound-guided site-specific cancer terminator virus delivery approach. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 295-306. PMID 19888195 DOI: 10.1038/Mt.2009.252  0.521
2010 Ugai H, Wang M, Le LP, Matthews DA, Yamamoto M, Curiel DT. In vitro dynamic visualization analysis of fluorescently labeled minor capsid protein IX and core protein V by simultaneous detection. Journal of Molecular Biology. 395: 55-78. PMID 19853616 DOI: 10.1016/J.Jmb.2009.10.034  0.332
2010 Rein DT, Schmidt T, Bauerschmitz G, Hampl M, Beyer IM, Paupoo AA, Curiel DT, Breidenbach M. Treatment of endometriosis with a VEGF-targeted conditionally replicative adenovirus. Fertility and Sterility. 93: 2687-94. PMID 19524222 DOI: 10.1016/J.Fertnstert.2009.04.042  0.309
2010 Curiel DT, Preuss M, Wang M, Kimball KJ, Barnes MN, Wan W, Siegal G, Harris R, Aurigemma R, Alvarez RD. A phase I study of the infectivity enhanced CRAd Ad5-Δ24RGD for recurrent gynecologic cancer. Journal of Clinical Oncology. 28: 5107-5107. DOI: 10.1200/Jco.2010.28.15_Suppl.5107  0.378
2010 Annan AC, Preuss MA, Borovjagin AV, Ugai H, Curiel DT. Abstract 1508: Development of a strategy to knock down SDF-1 using shRNA as a means to prevent pulmonary metastasis Cancer Research. 70: 1508-1508. DOI: 10.1158/1538-7445.Am10-1508  0.406
2010 Bhutia SK, Dash R, Azab B, Das S, Su Z, Lee S, Grant S, Dent P, Curiel DT, Sarkar D, Fisher PB. Abstract 1038: Defining the mechanism by which melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24)-induced autophagy switches to apoptosis in prostate cancer cells Cancer Research. 70: 1038-1038. DOI: 10.1158/1538-7445.Am10-1038  0.393
2009 Uchino J, Takayama K, Harada A, Kawakami Y, Inoue H, Curiel DT, Nakanishi Y. [hTERT promoter-based conditionally replicative adenoviruses are useful for lung cancer and other solid cancer treatment]. Fukuoka Igaku Zasshi = Hukuoka Acta Medica. 100: 338-48. PMID 20391937  0.318
2009 Kawakami Y, Curiel DT. Construction of adenovirus vectors for transcriptional targeting. Cold Spring Harbor Protocols. 2009: pdb.prot5219. PMID 20147171 DOI: 10.1101/Pdb.Prot5219  0.352
2009 Kawakami Y, Curiel DT. Construction of adenovirus vectors with RGD-modified fiber for transductional targeting. Cold Spring Harbor Protocols. 2009: pdb.prot5217. PMID 20147169 DOI: 10.1101/Pdb.Prot5217  0.331
2009 Tang Y, Wu H, Ugai H, Matthews QL, Curiel DT. Derivation of a triple mosaic adenovirus for cancer gene therapy. Plos One. 4: e8526. PMID 20046872 DOI: 10.1371/Journal.Pone.0008526  0.777
2009 Glasgow JN, Mikheeva G, Krasnykh V, Curiel DT. A strategy for adenovirus vector targeting with a secreted single chain antibody. Plos One. 4: e8355. PMID 20027223 DOI: 10.1371/Journal.Pone.0008355  0.445
2009 van de Ven R, Lindenberg JJ, Oosterhoff D, van den Tol MP, Rosalia RA, Murakami M, Everts M, Scheffer GL, Scheper RJ, de Gruijl TD, Curiel DT. Selective transduction of mature DC in human skin and lymph nodes by CD80/CD86-targeted fiber-modified adenovirus-5/3. Journal of Immunotherapy (Hagerstown, Md. : 1997). 32: 895-906. PMID 19816192 DOI: 10.1097/Cji.0B013E3181B56Deb  0.637
2009 Kimball KJ, Rivera AA, Zinn KR, Icyuz M, Saini V, Li J, Zhu ZB, Siegal GP, Douglas JT, Curiel DT, Alvarez RD, Borovjagin AV. Novel infectivity-enhanced oncolytic adenovirus with a capsid-incorporated dual-imaging moiety for monitoring virotherapy in ovarian cancer. Molecular Imaging. 8: 264-77. PMID 19796604 DOI: 10.2310/7290.2009.00025  0.595
2009 Thacker EE, Nakayama M, Smith BF, Bird RC, Muminova Z, Strong TV, Timares L, Korokhov N, O'Neill AM, de Gruijl TD, Glasgow JN, Tani K, Curiel DT. A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific immune responses in vivo. Vaccine. 27: 7116-24. PMID 19786146 DOI: 10.1016/J.Vaccine.2009.09.055  0.439
2009 Nelson AR, Davydova J, Curiel DT, Yamamoto M. Combination of conditionally replicative adenovirus and standard chemotherapies shows synergistic antitumor effect in pancreatic cancer. Cancer Science. 100: 2181-7. PMID 19689475 DOI: 10.1111/J.1349-7006.2009.01289.X  0.402
2009 Short JJ, Curiel DT. Oncolytic adenoviruses targeted to cancer stem cells. Molecular Cancer Therapeutics. 8: 2096-102. PMID 19671759 DOI: 10.1158/1535-7163.Mct-09-0367  0.741
2009 Matthews K, Noker PE, Tian B, Grimes SD, Fulton R, Schweikart K, Harris R, Aurigemma R, Wang M, Barnes MN, Siegal GP, Hemminki A, Zinn K, Curiel DT, Alvarez RD. Identifying the safety profile of Ad5.SSTR/TK.RGD, a novel infectivity-enhanced bicistronic adenovirus, in anticipation of a phase I clinical trial in patients with recurrent ovarian cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 4131-7. PMID 19509153 DOI: 10.1158/1078-0432.Ccr-08-3354  0.409
2009 Matthews KS, Alvarez RD, Curiel DT. Advancements in adenoviral based virotherapy for ovarian cancer. Advanced Drug Delivery Reviews. 61: 836-41. PMID 19422865 DOI: 10.1016/J.Addr.2009.04.012  0.361
2009 Park MA, Walker T, Martin AP, Allegood J, Vozhilla N, Emdad L, Sarkar D, Rahmani M, Graf M, Yacoub A, Koumenis C, Spiegel S, Curiel DT, Voelkel-Johnson C, Grant S, et al. MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism. Molecular Cancer Therapeutics. 8: 1280-91. PMID 19417161 DOI: 10.1158/1535-7163.Mct-09-0073  0.307
2009 Dent P, Curiel DT, Fisher PB, Grant S. Synergistic combinations of signaling pathway inhibitors: mechanisms for improved cancer therapy. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 12: 65-73. PMID 19395305 DOI: 10.1016/J.Drup.2009.03.001  0.369
2009 Kashentseva EA, Douglas JT, Zinn KR, Curiel DT, Dmitriev IP. Targeting of adenovirus serotype 5 pseudotyped with short fiber from serotype 41 to c-erbB2-positive cells using bispecific single-chain diabody. Journal of Molecular Biology. 388: 443-61. PMID 19285990 DOI: 10.1016/J.Jmb.2009.03.016  0.415
2009 Emdad L, Lebedeva IV, Su ZZ, Gupta P, Sauane M, Dash R, Grant S, Dent P, Curiel DT, Sarkar D, Fisher PB. Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24. Cancer Biology & Therapy. 8: 391-400. PMID 19276652 DOI: 10.4161/Cbt.8.5.7581  0.373
2009 Haisma HJ, Boesjes M, Beerens AM, van der Strate BW, Curiel DT, Plüddemann A, Gordon S, Bellu AR. Scavenger receptor A: a new route for adenovirus 5. Molecular Pharmaceutics. 6: 366-74. PMID 19227971 DOI: 10.1021/Mp8000974  0.644
2009 Li HJ, Everts M, Yamamoto M, Curiel DT, Herschman HR. Combined transductional untargeting/retargeting and transcriptional restriction enhances adenovirus gene targeting and therapy for hepatic colorectal cancer tumors. Cancer Research. 69: 554-64. PMID 19147569 DOI: 10.1158/0008-5472.Can-08-3209  0.452
2009 Hedley SJ, Krendelshchikov A, Kim MH, Chen J, Hsu HC, Mountz JD, Curiel DT, Kovesdi I. Assessment of genetic shielding for adenovirus vectors Open Gene Therapy Journal. 2: 1-11. DOI: 10.2174/1875037000902010001  0.419
2009 Stoff-Khalili M, Nedeljkovic-Kurepa A, Jung J, Glover B, Wappenschmidt B, Rhiem K, Bosse K, Mallmann P, Curiel D, Schmutzler R, Mathis M. Combination of oncolytic adenoviral therapy with chemotherapy for enhanced breast cancer cell killing. Cancer Research. 69: 2129. DOI: 10.1158/0008-5472.Sabcs-2129  0.457
2009 Stoff-Khalili M, Bhatia S, Odaka Y, Li X, Podduturi J, Smart L, Mallmann P, Schmutzler R, Curiel D, Mathis M. Ligand-mediated selective targeting of adenovirus in metastatic breast cancer. Cancer Research. 69: 2126. DOI: 10.1158/0008-5472.Sabcs-2126  0.472
2009 Othman E, Hornung D, El-Helw B, El-Maghraby H, Curiel D, Al-Hendy A. Targeting adenoviral gene therapy vectors towards human endometrial cells Fertility and Sterility. 92: S123. DOI: 10.1016/J.Fertnstert.2009.07.1145  0.436
2008 Preuss MA, Glasgow JN, Everts M, Stoff-Khalili MA, Wu H, Curiel DT. Enhanced Gene Delivery to Human Primary Endothelial Cells Using Tropism-Modified Adenovirus Vectors. The Open Gene Therapy Journal. 1: 7-11. PMID 19834585 DOI: 10.2174/1875037000801010007  0.7
2008 Park MA, Zhang G, Mitchell C, Rahmani M, Hamed H, Hagan MP, Yacoub A, Curiel DT, Fisher PB, Grant S, Dent P. Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95. Molecular Cancer Therapeutics. 7: 2633-48. PMID 18790746 DOI: 10.1158/1535-7163.Mct-08-0400  0.327
2008 San Martín C, Glasgow JN, Borovjagin A, Beatty MS, Kashentseva EA, Curiel DT, Marabini R, Dmitriev IP. Localization of the N-terminus of minor coat protein IIIa in the adenovirus capsid. Journal of Molecular Biology. 383: 923-34. PMID 18786542 DOI: 10.1016/J.Jmb.2008.08.054  0.738
2008 Zhang G, Park MA, Mitchell C, Hamed H, Rahmani M, Martin AP, Curiel DT, Yacoub A, Graf M, Lee R, Roberts JD, Fisher PB, Grant S, Dent P. Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 5385-99. PMID 18765530 DOI: 10.1158/1078-0432.Ccr-08-0469  0.312
2008 Paul CP, Everts M, Glasgow JN, Dent P, Fisher PB, Ulasov IV, Lesniak MS, Stoff-Khalili MA, Roth JC, Preuss MA, Dirven CM, Lamfers ML, Siegal GP, Zhu ZB, Curiel DT. Characterization of infectivity of knob-modified adenoviral vectors in glioma. Cancer Biology & Therapy. 7: 786-93. PMID 18756624 DOI: 10.4161/Cbt.7.5.5421  0.495
2008 Matthews QL, Yang P, Wu Q, Belousova N, Rivera AA, Stoff-Khalili MA, Waehler R, Hsu HC, Li Z, Li J, Mountz JD, Wu H, Curiel DT. Optimization of capsid-incorporated antigens for a novel adenovirus vaccine approach. Virology Journal. 5: 98. PMID 18718011 DOI: 10.1186/1743-422X-5-98  0.675
2008 Dent P, Yacoub A, Park M, Sarkar D, Shah K, Curiel DT, Grant S, Fisher PB. Searching for a cure: gene therapy for glioblastoma. Cancer Biology & Therapy. 7: 1335-40. PMID 18708757 DOI: 10.4161/Cbt.7.9.6408  0.373
2008 Othman EE, Zhu ZB, Curiel DT, Khatoon N, Salem HT, Khalifa EA, Al-Hendy A. Toward gene therapy of endometriosis: transductional and transcriptional targeting of adenoviral vectors to endometriosis cells. American Journal of Obstetrics and Gynecology. 199: 117.e1-6. PMID 18674655 DOI: 10.1016/J.Ajog.2008.01.059  0.466
2008 Tang Y, Le LP, Matthews QL, Han T, Wu H, Curiel DT. Derivation of a triple mosaic adenovirus based on modification of the minor capsid protein IX. Virology. 377: 391-400. PMID 18570971 DOI: 10.1016/J.Virol.2008.04.023  0.726
2008 Chen J, Wang J, Li J, Wu Q, Chu Lim F, Yang P, Hsu HC, Curiel DT, Mountz JD. Enhancement of cytotoxic T-lymphocyte response in aged mice by a novel treatment with recombinant AdIL-12 and wild-type adenovirus in rapid succession. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1500-6. PMID 18545221 DOI: 10.1038/Mt.2008.121  0.336
2008 Sekine S, Kataoka K, Fukuyama Y, Adachi Y, Davydova J, Yamamoto M, Kobayashi R, Fujihashi K, Suzuki H, Curiel DT, Shizukuishi S, McGhee JR, Fujihashi K. A novel adenovirus expressing Flt3 ligand enhances mucosal immunity by inducing mature nasopharyngeal-associated lymphoreticular tissue dendritic cell migration. Journal of Immunology (Baltimore, Md. : 1950). 180: 8126-34. PMID 18523277 DOI: 10.4049/Jimmunol.180.12.8126  0.371
2008 Tsuruta Y, Pereboeva L, Breidenbach M, Rein DT, Wang M, Alvarez RD, Siegal GP, Dent P, Fisher PB, Curiel DT. A fiber-modified mesothelin promoter-based conditionally replicating adenovirus for treatment of ovarian cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3582-8. PMID 18519792 DOI: 10.1158/1078-0432.Ccr-07-5053  0.401
2008 Zhu ZB, Lu B, Park M, Makhija SK, Numnum TM, Kendrick JE, Wang M, Tsuruta Y, Fisher P, Alvarez RD, Zhou F, Siegal GP, Wu H, Curiel DT. Development of an optimized conditionally replicative adenoviral agent for ovarian cancer. International Journal of Oncology. 32: 1179-88. PMID 18497979 DOI: 10.3892/Ijo_32_6_1179  0.719
2008 Wu H, Curiel DT. Fiber-modified adenoviruses for targeted gene therapy. Methods in Molecular Biology (Clifton, N.J.). 434: 113-32. PMID 18470642 DOI: 10.1007/978-1-60327-248-3_8  0.709
2008 Bird RC, Deinnocentes P, Lenz S, Thacker EE, Curiel DT, Smith BF. An allogeneic hybrid-cell fusion vaccine against canine mammary cancer. Veterinary Immunology and Immunopathology. 123: 289-304. PMID 18423623 DOI: 10.1016/J.Vetimm.2008.02.013  0.387
2008 Haviv YS, Curiel DT. Gene therapy for renal cancer. Contributions to Nephrology. 159: 135-50. PMID 18391590 DOI: 10.1159/000125687  0.417
2008 Yacoub A, Hamed H, Emdad L, Dos Santos W, Gupta P, Broaddus WC, Ramakrishnan V, Sarkar D, Shah K, Curiel DT, Grant S, Fisher PB, Dent P. MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors. Cancer Biology & Therapy. 7: 917-33. PMID 18376144 DOI: 10.4161/Cbt.7.6.5928  0.439
2008 Roth JC, Curiel DT, Pereboeva L. Cell vehicle targeting strategies Gene Therapy. 15: 716-729. PMID 18369326 DOI: 10.1038/Gt.2008.38  0.393
2008 Curiel D. Introduction to special issue on cellular vehicles Gene Therapy. 15: 703-703. PMID 18369323 DOI: 10.1038/Gt.2008.46  0.325
2008 Ramírez PJ, Vickers SM, Ono HA, Davydova J, Takayama K, Thompson TC, Curiel DT, Bland KI, Yamamoto M. Optimization of conditionally replicative adenovirus for pancreatic cancer and its evaluation in an orthotopic murine xenograft model American Journal of Surgery. 195: 481-490. PMID 18361926 DOI: 10.1016/J.Amjsurg.2007.04.014  0.448
2008 Sarkar D, Su ZZ, Park ES, Vozhilla N, Dent P, Curiel DT, Fisher PB. A cancer terminator virus eradicates both primary and distant human melanomas. Cancer Gene Therapy. 15: 293-302. PMID 18323853 DOI: 10.1038/cgt.2008.14  0.398
2008 Park MA, Yacoub A, Sarkar D, Emdad L, Rahmani M, Spiegel S, Koumenis C, Graf M, Curiel DT, Grant S, Fisher PB, Dent P. PERK-dependent regulation of MDA-7/IL-24-induced autophagy in primary human glioma cells. Autophagy. 4: 513-5. PMID 18299661 DOI: 10.4161/Auto.5725  0.365
2008 Yacoub A, Gupta P, Park MA, Rhamani M, Hamed H, Hanna D, Zhang G, Sarkar D, Lebedeva IV, Emdad L, Koumenis C, Curiel DT, Grant S, Fisher PB, Dent P. Regulation of GST-MDA-7 toxicity in human glioblastoma cells by ERBB1, ERK1/2, PI3K, and JNK1-3 pathway signaling Molecular Cancer Therapeutics. 7: 314-329. PMID 18281516 DOI: 10.1158/1535-7163.Mct-07-2150  0.345
2008 Yacoub A, Park MA, Gupta P, Rahmani M, Zhang G, Hamed H, Hanna D, Sarkar D, Lebedeva IV, Emdad L, Sauane M, Vozhilla N, Spiegel S, Koumenis C, Graf M, ... Curiel DT, et al. Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells. Molecular Cancer Therapeutics. 7: 297-313. PMID 18281515 DOI: 10.1158/1535-7163.Mct-07-2166  0.356
2008 Sarkar D, Dent P, Curiel DT, Fisher PB. Acquired and innate resistance to the cancer-specific apoptosis-inducing cytokine, mda-7/IL-24: Not insurmountable therapeutic problems Cancer Biology and Therapy. 7: 109-112. PMID 18277093 DOI: 10.4161/Cbt.7.1.5693  0.446
2008 Gupta P, Emdad L, Lebedeva IV, Sarkar D, Dent P, Curiel DT, Settleman J, Fisher PB. Targeted combinatorial therapy of non-small cell lung carcinoma using a GST-fusion protein of full-length or truncated MDA-7/IL-24 with Tarceva. Journal of Cellular Physiology. 215: 827-36. PMID 18270968 DOI: 10.1002/Jcp.21369  0.345
2008 Park MA, Curiel DT, Koumenis C, Graf M, Chen CS, Fisher PB, Grant S, Dent P. PERK-dependent regulation of HSP70 expression and the regulation of autophagy. Autophagy. 4: 364-7. PMID 18216498 DOI: 10.4161/Auto.5593  0.312
2008 Schoehn G, El Bakkouri ME, Fabry CMS, Billet O, Estrozi LF, Le L, Curiel DT, Kajava AV, Ruigrok RWH, Kremer EJ. Three-dimensional structure of canine adenovirus serotype 2 capsid Journal of Virology. 82: 3192-3203. PMID 18216088 DOI: 10.1128/Jvi.02393-07  0.306
2008 Saini V, Martyshkin DV, Mirov SB, Perez A, Perkins G, Ellisman MH, Towner VD, Wu H, Pereboeva L, Borovjagin A, Curiel DT, Everts M. An adenoviral platform for selective self-assembly and targeted delivery of nanoparticles. Small (Weinheim An Der Bergstrasse, Germany). 4: 262-9. PMID 18200644 DOI: 10.1002/Smll.200700403  0.753
2008 Hassan MH, Khatoon N, Curiel DT, Hamada FM, Arafa HM, Al-Hendy A. Toward gene therapy of uterine fibroids: targeting modified adenovirus to human leiomyoma cells. Human Reproduction (Oxford, England). 23: 514-24. PMID 18184643 DOI: 10.1093/Humrep/Dem410  0.467
2008 Park MA, Yacoub A, Rahmani M, Zhang G, Hart L, Hagan MP, Calderwood SK, Sherman MY, Koumenis C, Spiegel S, Chen CS, Graf M, Curiel DT, Fisher PB, Grant S, et al. OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells. Molecular Pharmacology. 73: 1168-84. PMID 18182481 DOI: 10.1124/Mol.107.042697  0.309
2008 Uchino J, Takayama K, Harada A, Sone T, Harada T, Curiel DT, Kuroki M, Nakanishi Y. Tumor targeting carboxylesterase fused with anti-CEA scFv improve the anticancer effect with a less toxic dose of irinotecan Cancer Gene Therapy. 15: 94-100. PMID 18157147 DOI: 10.1038/Sj.Cgt.7701100  0.401
2008 Brumlik MJ, Daniel BJ, Waehler R, Curiel DT, Giles FJ, Curiel TJ. Trends in immunoconjugate and ligand-receptor based targeting development for cancer therapy Expert Opinion On Drug Delivery. 5: 87-103. PMID 18095930 DOI: 10.1517/17425247.5.1.87  0.362
2008 Numnum TM, Makhija S, Lu B, Wang M, Rivera A, Stoff-Khalili M, Alvarez RD, Zhu ZB, Curiel DT. Improved anti-tumor therapy based upon infectivity-enhanced adenoviral delivery of RNA interference in ovarian carcinoma cell lines. Gynecologic Oncology. 108: 34-41. PMID 18061250 DOI: 10.1016/J.Ygyno.2007.08.096  0.461
2008 Huang D, Pereboev AV, Korokhov N, He R, Larocque L, Gravel C, Jaentschke B, Tocchi M, Casley WL, Lemieux M, Curiel DT, Chen W, Li X. Significant alterations of biodistribution and immune responses in Balb/c mice administered with adenovirus targeted to CD40(+) cells. Gene Therapy. 15: 298-308. PMID 18046426 DOI: 10.1038/Sj.Gt.3303085  0.372
2008 Schierer S, Hesse A, Müller I, Kämpgen E, Curiel DT, Schuler G, Steinkasserer A, Nettelbeck DM. Modulation of viability and maturation of human monocyte-derived dendritic cells by oncolytic adenoviruses International Journal of Cancer. 122: 219-229. PMID 17764070 DOI: 10.1002/Ijc.23074  0.41
2008 Stoff-Khalili MA, Rivera AA, Nedeljkovic-Kurepa A, DeBenedetti A, Li XL, Odaka Y, Podduturi J, Sibley DA, Siegal GP, Stoff A, Young S, Zhu ZB, Curiel DT, Mathis JM. Cancer-specific targeting of a conditionally replicative adenovirus using mRNA translational control. Breast Cancer Research and Treatment. 108: 43-55. PMID 17508279 DOI: 10.1007/S10549-007-9587-7  0.403
2008 Reynolds PN, Curiel DT. New generation adenoviral vectors improve gene transfer by coxsackie and adenoviral receptor-independent cell entry. Kidney International. 61: S24-31. PMID 11841608 DOI: 10.1046/J.1523-1755.2002.0610S1024.X  0.461
2008 Sarkar D, Dent P, Curiel DT, Fisher PB. INGN-241: Cancer gene therapy Drugs of the Future. 33: 396-401. DOI: 10.1358/Dof.2008.033.05.1201624  0.443
2008 Jung J, Nedeljkovic-Kurepa A, Glover B, Curiel D, Schmutzler R, Mathis J, Stoff-Khalili M. Combination of Oncolytic Adenoviral Therapy with Chemotherapy for Enhanced Breast Cancer Cell Killing – Virotherapy in combination with chemotherapy Geburtshilfe Und Frauenheilkunde. 68. DOI: 10.1055/S-0028-1088821  0.334
2008 Nettelbeck DM, Alvarez RD, Curiel DT. Tumor-Busting Viruses Scientific American Sp. 18: 72-79. DOI: 10.1038/Scientificamerican1003-68  0.311
2007 Mitchell C, Park MA, Zhang G, Yacoub A, Curiel DT, Fisher PB, Roberts JD, Grant S, Dent P. Extrinsic pathway- and cathepsin-dependent induction of mitochondrial dysfunction are essential for synergistic flavopiridol and vorinostat lethality in breast cancer cells. Molecular Cancer Therapeutics. 6: 3101-12. PMID 18065490 DOI: 10.1158/1535-7163.Mct-07-0561  0.332
2007 Emdad L, Lebedeva IV, Su ZZ, Sarkar D, Dent P, Curiel DT, Fisher PB. Melanoma differentiation associated gene-7/interleukin-24 reverses multidrug resistance in human colorectal cancer cells. Molecular Cancer Therapeutics. 6: 2985-94. PMID 18025283 DOI: 10.1158/1535-7163.Mct-07-0399  0.361
2007 Zhu ZB, Mathis JM, Makhija SK, Lu B, Wang M, Ji S, Rivera AA, Rosenthal EL, Siegal GP, Curiel DT. Targeting of a conditionally replicative adenovirus agent to human squamous cell carcinomas of the head and neck. International Journal of Oncology. 31: 1213-22. PMID 17912450 DOI: 10.3892/Ijo.31.5.1213  0.465
2007 Lebedeva IV, Emdad L, Su ZZ, Gupta P, Sauane M, Sarkar D, Staudt MR, Liu SJ, Taher MM, Xiao R, Barral P, Lee SG, Wang D, Vozhilla N, Park ES, ... ... Curiel DT, et al. mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review). International Journal of Oncology. 31: 985-1007. PMID 17912425 DOI: 10.3892/Ijo.31.5.985  0.381
2007 Ulasov IV, Rivera AA, Han Y, Curiel DT, Zhu ZB, Lesniak MS. Targeting adenovirus to CD80 and CD86 receptors increases gene transfer efficiency to malignant glioma cells Journal of Neurosurgery. 107: 617-627. PMID 17886563 DOI: 10.3171/Jns-07/09/0617  0.362
2007 Miura Y, Yoshida K, Nishimoto T, Hatanaka K, Ohnami S, Asaka M, Douglas JT, Curiel DT, Yoshida T, Aoki K. Direct selection of targeted adenovirus vectors by random peptide display on the fiber knob. Gene Therapy. 14: 1448-60. PMID 17700705 DOI: 10.1038/Sj.Gt.3303007  0.399
2007 Gaballah K, Hills A, Curiel D, Hallden G, Harrison P, Partridge M. Lysis of dysplastic but not normal oral keratinocytes and tissue-engineered epithelia with conditionally replicating adenoviruses Cancer Research. 67: 7284-7294. PMID 17671197 DOI: 10.1158/0008-5472.Can-06-3834  0.329
2007 Ulasov IV, Zhu ZB, Tyler MA, Han Y, Rivera AA, Khramtsov A, Curiel DT, Lesniak MS. Survivin-driven and fiber-modified oncolytic adenovirus exhibits potent antitumor activity in established intracranial glioma Human Gene Therapy. 18: 589-602. PMID 17630837 DOI: 10.1089/Hum.2007.002  0.457
2007 Waehler R, Russell SJ, Curiel DT. Engineering targeted viral vectors for gene therapy Nature Reviews Genetics. 8: 573-587. PMID 17607305 DOI: 10.1038/Nrg2141  0.445
2007 Mitchell C, Kabolizadeh P, Ryan J, Roberts JD, Yacoub A, Curiel DT, Fisher PB, Hagan MP, Farrell NP, Grant S, Dent P. Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling. Molecular Pharmacology. 72: 704-14. PMID 17578896 DOI: 10.1124/Mol.107.038406  0.361
2007 Sarkar D, Lebedeva IV, Su ZZ, Park ES, Chatman L, Vozhilla N, Dent P, Curiel DT, Fisher PB. Eradication of therapy-resistant human prostate tumors using a cancer terminator virus. Cancer Research. 67: 5434-42. PMID 17545625 DOI: 10.1158/0008-5472.Can-07-0195  0.429
2007 Li HJ, Everts M, Pereboeva L, Komarova S, Idan A, Curiel DT, Herschman HR. Adenovirus tumor targeting and hepatic untargeting by a coxsackie/adenovirus receptor ectodomain anti-carcinoembryonic antigen bispecific adapter. Cancer Research. 67: 5354-61. PMID 17545616 DOI: 10.1158/0008-5472.Can-06-4679  0.42
2007 Van Houdt WJ, Wu H, Glasgow JN, Lamfers ML, Dirven CM, Gillespie GY, Curiel DT, Haviv YS. Gene delivery into malignant glioma by infectivity-enhanced adenovirus: in vivo versus in vitro models. Neuro-Oncology. 9: 280-90. PMID 17522331 DOI: 10.1215/15228517-2007-017  0.782
2007 Sarkar D, Lebedeva IV, Gupta P, Emdad L, Sauane M, Dent P, Curiel DT, Fisher PB. Melanoma differentiation associated gene-7 (mda-7)/IL-24: A 'magic bullet' for cancer therapy? Expert Opinion On Biological Therapy. 7: 577-586. PMID 17477796 DOI: 10.1517/14712598.7.5.577  0.43
2007 Tsuruta Y, Pereboeva L, Glasgow JN, Rein DT, Kawakami Y, Alvarez RD, Rocconi RP, Siegal GP, Dent P, Fisher PB, Curiel DT. A mosaic fiber adenovirus serotype 5 vector containing reovirus sigma 1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 2777-83. PMID 17473211 DOI: 10.1158/1078-0432.Ccr-06-2706  0.461
2007 Page JG, Tian B, Schweikart K, Tomaszewski J, Harris R, Broadt T, Polley-Nelson J, Noker PE, Wang M, Makhija S, Aurigemma R, Curiel DT, Alvarez RD. Identifying the safety profile of a novel infectivity-enhanced conditionally replicative adenovirus, Ad5-delta24-RGD, in anticipation of a phase I trial for recurrent ovarian cancer. American Journal of Obstetrics and Gynecology. 196: 389.e1-9; discussion. PMID 17403430 DOI: 10.1016/J.Ajog.2006.12.016  0.396
2007 Valerie K, Yacoub A, Hagan MP, Curiel DT, Fisher PB, Grant S, Dent P. Radiation-induced cell signaling: inside-out and outside-in. Molecular Cancer Therapeutics. 6: 789-801. PMID 17363476 DOI: 10.1158/1535-7163.Mct-06-0596  0.316
2007 Lebedeva IV, Washington I, Sarkar D, Clark JA, Fine RL, Dent P, Curiel DT, Turro NJ, Fisher PB. Strategy for reversing resistance to a single anticancer agent in human prostate and pancreatic carcinomas. Proceedings of the National Academy of Sciences of the United States of America. 104: 3484-9. PMID 17360670 DOI: 10.1073/Pnas.0700042104  0.374
2007 Yoshio-Hoshino N, Adachi Y, Aoki C, Pereboev A, Curiel DT, Nishimoto N. Establishment of a new interleukin-6 (IL-6) receptor inhibitor applicable to the gene therapy for IL-6-dependent tumor. Cancer Research. 67: 871-5. PMID 17283116 DOI: 10.1158/0008-5472.Can-06-3641  0.328
2007 Preuss MA, Curiel DT. Gene therapy: science fiction or reality? Southern Medical Journal. 100: 101-4. PMID 17269545 DOI: 10.1097/Smj.0B013E31802E65Dd  0.313
2007 Matthews QL, Curiel DT. Gene therapy: Human germline genetic modifications - Assessing the scientific, socioethical, and religious issues Southern Medical Journal. 100: 98-100. PMID 17269544 DOI: 10.1097/Smj.0B013E31802E645F  0.318
2007 Pereboeva L, Komarova S, Roth J, Ponnazhagan S, Curiel DT. Targeting EGFR with metabolically biotinylated fiber-mosaic adenovirus Gene Therapy. 14: 627-637. PMID 17251987 DOI: 10.1038/Sj.Gt.3302916  0.438
2007 Lam JT, Hemminki A, Kanerva A, Lee KB, Blackwell JL, Desmond R, Siegal GP, Curiel DT. A three-dimensional assay for measurement of viral-induced oncolysis Cancer Gene Therapy. 14: 421-430. PMID 17235353 DOI: 10.1038/Sj.Cgt.7701028  0.41
2007 Perreau M, Mennechet F, Serratrice N, Glasgow JN, Curiel DT, Wodrich H, Kremer EJ. Contrasting effects of human, canine, and hybrid adenovirus vectors on the phenotypical and functional maturation of human dendritic cells: implications for clinical efficacy. Journal of Virology. 81: 3272-84. PMID 17229706 DOI: 10.1128/Jvi.01530-06  0.41
2007 Stoff-Khalili MA, Rivera AA, Mathis JM, Banerjee NS, Moon AS, Hess A, Rocconi RP, Numnum TM, Everts M, Chow LT, Douglas JT, Siegal GP, Zhu ZB, Bender HG, Dall P, ... ... Curiel DT, et al. Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma. Breast Cancer Research and Treatment. 105: 157-67. PMID 17221158 DOI: 10.1007/S10549-006-9449-8  0.381
2007 Fisher PB, Sarkar D, Lebedeva IV, Emdad L, Gupta P, Sauane M, Su ZZ, Grant S, Dent P, Curiel DT, Senzer N, Nemunaitis J. Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): novel gene therapeutic for metastatic melanoma. Toxicology and Applied Pharmacology. 224: 300-7. PMID 17208263 DOI: 10.1016/J.Taap.2006.11.021  0.424
2007 Ugai H, Borovjagin AV, Le LP, Wang M, Curiel DT. Thermostability/Infectivity Defect Caused by Deletion of the Core Protein V Gene in Human Adenovirus Type 5 Is Rescued by Thermo-selectable Mutations in the Core Protein X Precursor Journal of Molecular Biology. 366: 1142-1160. PMID 17208253 DOI: 10.1016/J.Jmb.2006.11.090  0.404
2007 Witlox MA, Lamfers ML, Wuisman PIJM, Curiel DT, Siegal GP. Evolving gene therapy approaches for osteosarcoma using viral vectors: Review Bone. 40: 797-812. PMID 17189720 DOI: 10.1016/J.Bone.2006.10.017  0.45
2007 Rocconi RP, Zhu ZB, Stoff-Khalili M, Rivera AA, Lu B, Wang M, Alvarez RD, Curiel DT, Makhija SK. Treatment of ovarian cancer with a novel dual targeted conditionally replicative adenovirus (CRAd) Gynecologic Oncology. 105: 113-121. PMID 17173958 DOI: 10.1016/J.Ygyno.2006.10.057  0.428
2007 Tang Y, Han T, Everts M, Zhu ZB, Gillespie GY, Curiel DT, Wu H. Directing adenovirus across the blood-brain barrier via melanotransferrin (P97) transcytosis pathway in an in vitro model. Gene Therapy. 14: 523-32. PMID 17167498 DOI: 10.1038/Sj.Gt.3302888  0.778
2007 Stoff-Khalili MA, Rivera AA, Stoff A, Mathis JM, Rocconi RP, Matthews QL, Numnum MT, Herrmann I, Dall P, Eckhoff DE, Douglas JT, Siegal GP, Zhu ZB, Curiel DT. Combining high selectivity of replication via CXCR4 promoter with fiber chimerism for effective adenoviral oncolysis in breast cancer International Journal of Cancer. 120: 935-941. PMID 17131341 DOI: 10.1002/Ijc.22338  0.453
2007 Zhu ZB, Rivera AA, Makhija SK, Lu B, Wang M, Izumi M, Cerfolio RJ, Stoff-Khalili MA, Zhou F, Takayama K, Siegal GP, Curiel DT. Targeting lung cancer using an infectivity enhanced CXCR4-CRAd Lung Cancer. 55: 145-156. PMID 17113184 DOI: 10.1016/J.Lungcan.2006.10.012  0.453
2007 Yacoub A, Hawkins W, Hanna D, Young H, Park MA, Grant M, Roberts JD, Curiel DT, Fisher PB, Valerie K, Grant S, Hagan MP, Dent P. Human chorionic gonadotropin modulates prostate cancer cell survival after irradiation or HMG CoA reductase inhibitor treatment. Molecular Pharmacology. 71: 259-75. PMID 17050804 DOI: 10.1124/Mol.106.031153  0.329
2007 Takayama K, Reynolds PN, Adachi Y, Kaliberova L, Uchino J, Nakanishi Y, Curiel DT. Vascular endothelial growth factor promoter-based conditionally replicative adenoviruses for pan-carcinoma application Cancer Gene Therapy. 14: 105-116. PMID 17024232 DOI: 10.1038/Sj.Cgt.7700991  0.411
2007 Jung JS, Stoff A, Rivera AA, Mathis JM, Hess A, Rein D, Fleisch MC, Dall P, Curiel DT, Niederacher D, Bender HG, Stoff-Khalili MA. Stem cells as cellular vehicles for virotherapeutic agents in metastatic breast cancer | Stammzellen als zelluläre vehikel virotherapeutischer agenzien beim metastasierten mammakarzinom Geburtshilfe Und Frauenheilkunde. 67: 236-241. DOI: 10.1055/S-2007-965053  0.382
2006 Gommans WM, Oosterhuis D, Dmitriev I, Schaack J, Curiel DT, Haisma HJ, Rots MG. Towards a double controlled conditionally replicative adenovirus for potent and specific melanoma cell kill. Journal of Controlled Release : Official Journal of the Controlled Release Society. 116: e64-6. PMID 17718975 DOI: 10.1016/J.Jconrel.2006.09.052  0.599
2006 Smith BF, Curiel DT, Ternovoi VV, Borovjagin AV, Baker HJ, Cox N, Siegal GP. Administration of a conditionally replicative oncolytic canine adenovirus in normal dogs. Cancer Biotherapy & Radiopharmaceuticals. 21: 601-6. PMID 17257075 DOI: 10.1089/Cbr.2006.21.601  0.387
2006 Matthews QL, Sibley DA, Wu H, Li J, Stoff-Khalili MA, Waehler R, Mathis JM, Curiel DT. Genetic incorporation of a herpes simplex virus type 1 thymidine kinase and firefly luciferase fusion into the adenovirus protein IX for functional display on the virion. Molecular Imaging. 5: 510-9. PMID 17150163 DOI: 10.2310/7290.2006.00029  0.682
2006 Zhu ZB, Chen Y, Makhija SK, Lu B, Wang M, Rivera AA, Yamamoto M, Wang S, Siegal GP, Curiel DT, McDonald JM. Survivin promoter-based conditionally replicative adenoviruses target cholangiocarcinoma. International Journal of Oncology. 29: 1319-29. PMID 17016667 DOI: 10.3892/Ijo.29.5.1319  0.456
2006 Stoff A, Rivera AA, Banerjee NS, Mathis JM, Espinosa-de-los-Monteros A, Le LP, De la Torre JI, Vasconez LO, Broker TR, Richter DF, Stoff-Khalili MA, Curiel DT. Strategies to enhance transductional efficiency of adenoviral-based gene transfer to primary human fibroblasts and keratinocytes as a platform in dermal wounds. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 14: 608-17. PMID 17014674 DOI: 10.1111/J.1743-6109.2006.00168.X  0.463
2006 Tyler MA, Ulasov IV, Borovjagin A, Sonabend AM, Khramtsov A, Han Y, Dent P, Fisher PB, Curiel DT, Lesniak MS. Enhanced transduction of malignant glioma with a double targeted Ad5/3-RGD fiber-modified adenovirus Molecular Cancer Therapeutics. 5: 2408-2416. PMID 16985075 DOI: 10.1158/1535-7163.Mct-06-0187  0.497
2006 Abid MR, Shih SC, Otu HH, Spokes KC, Okada Y, Curiel DT, Minami T, Aird WC. A novel class of vascular endothelial growth factor-responsive genes that require forkhead activity for expression. The Journal of Biological Chemistry. 281: 35544-53. PMID 16980307 DOI: 10.1074/Jbc.M608620200  0.336
2006 Hakkarainen T, Hemminki A, Curiel DT, Wahlfors J. A conditionally replicative adenovirus that codes for a TK-GFP fusion protein (Ad5Delta24TK-GFP) for evaluation of the potency of oncolytic virotherapy combined with molecular chemotherapy. International Journal of Molecular Medicine. 18: 751-9. PMID 16964432 DOI: 10.3892/Ijmm.18.4.751  0.453
2006 Yacoub A, Gilfor D, Hawkins W, Park MA, Hanna D, Hagan MP, Curiel DT, Fisher PB, Grant S, Dent P. MEK1/2 inhibition promotes Taxotere lethality in mammary tumors in vivo. Cancer Biology & Therapy. 5: 1332-9. PMID 16957420 DOI: 10.4161/Cbt.5.10.3215  0.343
2006 Short JJ, Vasu C, Holterman MJ, Curiel DT, Pereboev A. Members of adenovirus species B utilize CD80 and CD86 as cellular attachment receptors. Virus Research. 122: 144-53. PMID 16920215 DOI: 10.1016/J.Virusres.2006.07.009  0.691
2006 Belousova N, Harris R, Zinn K, Rhodes-Selser MA, Kotov A, Kotova O, Wang M, Aurigemma R, Zhu ZB, Curiel DT, Alvarez RD. Circumventing recombination events encountered with production of a clinical-grade adenoviral vector with a double-expression cassette. Molecular Pharmacology. 70: 1488-93. PMID 16896072 DOI: 10.1124/Mol.106.025619  0.429
2006 Rocconi RP, Numnum MT, Zhu ZB, Lu B, Wang M, Rivera AA, Stoff-Khalili M, Alvarez RD, Curiel DT, Makhija S. Icodextrin enhances survival in an intraperitoneal ovarian cancer murine model utilizing gene therapy Gynecologic Oncology. 103: 985-989. PMID 16857247 DOI: 10.1016/J.Ygyno.2006.06.005  0.412
2006 Chen J, Hsu HC, Zajac AJ, Wu Q, Yang P, Xu X, McPherson SA, Li J, Curiel DT, Mountz JD. In vivo analysis of adenovirus-specific cytotoxic T lymphocyte response in mice deficient in CD28, fas ligand, and perforin. Human Gene Therapy. 17: 669-82. PMID 16776575 DOI: 10.1089/Hum.2006.17.669  0.413
2006 Ternovoi VV, Curiel DT, Smith BF, Siegal GP. Adenovirus-mediated p53 tumor suppressor gene therapy of osteosarcoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 748-66. PMID 16751779 DOI: 10.1038/Labinvest.3700444  0.434
2006 Kangasniemi L, Kiviluoto T, Kanerva A, Raki M, Ranki T, Sarkioja M, Wu H, Marini F, Höckerstedt K, Isoniemi H, Alfthan H, Stenman UH, Curiel DT, Hemminki A. Infectivity-enhanced adenoviruses deliver efficacy in clinical samples and orthotopic models of disseminated gastric cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 3137-44. PMID 16707613 DOI: 10.1158/1078-0432.Ccr-05-2576  0.682
2006 Le LP, Le HN, Nelson AR, Matthews DA, Yamamoto M, Curiel DT. Core labeling of adenovirus with EGFP Virology. 351: 291-302. PMID 16678874 DOI: 10.1016/J.Virol.2006.03.042  0.396
2006 Mathis JM, Stewart PL, Zhu ZB, Curiel DT. Advanced generation adenoviral virotherapy agents embody enhanced potency based upon CAR-independent tropism. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 2651-6. PMID 16675555 DOI: 10.1158/1078-0432.Ccr-06-0497  0.369
2006 Emdad L, Sarkar D, Lebedeva IV, Su ZZ, Gupta P, Mahasreshti PJ, Dent P, Curiel DT, Fisher PB. Ionizing radiation enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human ovarian cancer. Journal of Cellular Physiology. 208: 298-306. PMID 16646087 DOI: 10.1002/Jcp.20663  0.429
2006 Van Houdt WJ, Haviv YS, Lu B, Wang M, Rivera AA, Ulasov IV, Lamfers MLM, Rein D, Lesniak MS, Siegal GP, Dirven CMF, Curiel DT, Zhu ZB. The human survivin promoter: A novel transcriptional targeting strategy for treatment of glioma Journal of Neurosurgery. 104: 583-592. PMID 16619663 DOI: 10.3171/Jns.2006.104.4.583  0.39
2006 Hedley SJ, Chen J, Mountz JD, Li J, Curiel DT, Korokhov N, Kovesdi I. Targeted and shielded adenovectors for cancer therapy. Cancer Immunology, Immunotherapy : Cii. 55: 1412-9. PMID 16612598 DOI: 10.1007/S00262-006-0158-2  0.488
2006 Everts M, Saini V, Leddon JL, Kok RJ, Stoff-Khalili M, Preuss MA, Millican CL, Perkins G, Brown JM, Bagaria H, Nikles DE, Johnson DT, Zharov VP, Curiel DT. Covalently linked Au nanoparticles to a viral vector: potential for combined photothermal and gene cancer therapy. Nano Letters. 6: 587-91. PMID 16608249 DOI: 10.1021/Nl0500555  0.606
2006 Bauerschmitz GJ, Guse K, Kanerva A, Menzel A, Herrmann I, Desmond RA, Yamamoto M, Nettelbeck DM, Hakkarainen T, Dall P, Curiel DT, Hemminki A. Triple-targeted oncolytic adenoviruses featuring the cox2 promoter, E1A transcomplementation, and serotype chimerism for enhanced selectivity for ovarian cancer cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 164-74. PMID 16580264 DOI: 10.1016/J.Ymthe.2006.01.010  0.45
2006 Rein DT, Breidenbach M, Hille S, Curiel DT. Current developments in adenovirus-based cancer gene therapy Future Oncology. 2: 137-144. PMID 16556080 DOI: 10.2217/14796694.2.1.137  0.507
2006 Komarova S, Kawakami Y, Stoff-Khalili MA, Curiel DT, Pereboeva L. Mesenchymal progenitor cells as cellular vehicles for delivery of oncolytic adenoviruses. Molecular Cancer Therapeutics. 5: 755-66. PMID 16546991 DOI: 10.1158/1535-7163.Mct-05-0334  0.479
2006 Nakayama M, Both GW, Banizs B, Tsuruta Y, Yamamoto S, Kawakami Y, Douglas JT, Tani K, Curiel DT, Glasgow JN. An adenovirus serotype 5 vector with fibers derived from ovine atadenovirus demonstrates CAR-independent tropism and unique biodistribution in mice. Virology. 350: 103-15. PMID 16516257 DOI: 10.1016/J.Virol.2006.01.037  0.43
2006 Curiel DT, Zhu ZB. Combining chemotherapy with virotherapy: a novel treatment strategy for malignant pleural mesothelioma. Cancer Biology & Therapy. 5: 236-7. PMID 16481733 DOI: 10.4161/Cbt.5.2.2564  0.35
2006 Gupta P, Su ZZ, Lebedeva IV, Sarkar D, Sauane M, Emdad L, Bachelor MA, Grant S, Curiel DT, Dent P, Fisher PB. mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine. Pharmacology & Therapeutics. 111: 596-628. PMID 16464504 DOI: 10.1016/J.Pharmthera.2005.11.005  0.411
2006 Rocconi RP, Numnum TM, Stoff-Khalili M, Makhija S, Alvarez RD, Curiel DT. Targeted gene therapy for ovarian cancer. Current Gene Therapy. 5: 643-53. PMID 16457653 DOI: 10.2174/156652305774964668  0.439
2006 Le LP, Le HN, Dmitriev IP, Davydova JG, Gavrikova T, Yamamoto S, Curiel DT, Yamamoto M. Dynamic monitoring of oncolytic adenovirus in vivo by genetic capsid labeling. Journal of the National Cancer Institute. 98: 203-14. PMID 16449680 DOI: 10.1093/Jnci/Djj022  0.349
2006 Glasgow JN, Everts M, Curiel DT. Transductional targeting of adenovirus vectors for gene therapy. Cancer Gene Therapy. 13: 830-44. PMID 16439993 DOI: 10.1038/Sj.Cgt.7700928  0.488
2006 Gomez-Manzano C, Alonso MM, Yung WK, McCormick F, Curiel DT, Lang FF, Jiang H, Bekele BN, Zhou X, Alemany R, Fueyo J. Delta-24 increases the expression and activity of topoisomerase I and enhances the antiglioma effect of irinotecan. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 556-62. PMID 16428500 DOI: 10.1158/1078-0432.Ccr-05-1892  0.314
2006 Stoff-Khalili MA, Dall P, Curiel DT. Gene therapy for carcinoma of the breast. Cancer Gene Therapy. 13: 633-47. PMID 16410823 DOI: 10.1038/Sj.Cgt.7700929  0.367
2006 Stoff-Khalili MA, Rivera AA, Le LP, Stoff A, Everts M, Contreras JL, Chen D, Teng L, Rots MG, Haisma HJ, Rocconi RP, Bauerschmitz GJ, Rein DT, Yamamoto M, Siegal GP, ... ... Curiel DT, et al. Employment of liver tissue slice analysis to assay hepatotoxicity linked to replicative and nonreplicative adenoviral agents Cancer Gene Therapy. 13: 606-618. PMID 16410819 DOI: 10.1038/Sj.Cgt.7700934  0.566
2006 Lee CT, Lee YJ, Kwon SY, Lee J, Kim KI, Park KH, Kang JH, Yoo CG, Kim YW, Han SK, Chung JK, Shim YS, Curiel DT, Carbone DP. In vivo imaging of adenovirus transduction and enhanced therapeutic efficacy of combination therapy with conditionally replicating adenovirus and adenovirus-p27. Cancer Research. 66: 372-7. PMID 16397251 DOI: 10.1158/0008-5472.Can-05-1515  0.489
2006 Noureddini SC, Krendelshchikov A, Simonenko V, Hedley SJ, Douglas JT, Curiel DT, Korokhov N. Generation and selection of targeted adenoviruses embodying optimized vector properties. Virus Research. 116: 185-95. PMID 16293334 DOI: 10.1016/J.Virusres.2005.10.002  0.422
2006 Le LP, Rivera AA, Glasgow JN, Ternovoi VV, Wu H, Wang M, Smith BF, Siegal GP, Curiel DT. Infectivity enhancement for adenoviral transduction of canine osteosarcoma cells. Gene Therapy. 13: 389-99. PMID 16292351 DOI: 10.1038/Sj.Gt.3302674  0.482
2006 Breidenbach M, Rein DT, Schöndorf T, Khan KN, Herrmann I, Schmidt T, Reynolds PN, Vlodavsky I, Haviv YS, Curiel DT. A new targeting approach for breast cancer gene therapy using the Heparanase promoter Cancer Letters. 240: 114-122. PMID 16271435 DOI: 10.1016/J.Canlet.2005.09.007  0.4
2006 Mahasreshti PJ, Kataram M, Wu H, Yalavarthy LP, Carey D, Fisher PB, Chada S, Alvarez RD, Haisma HJ, Dent P, Curiel DT. Ovarian cancer targeted adenoviral-mediated mda-7/IL-24 gene therapy. Gynecologic Oncology. 100: 521-32. PMID 16225913 DOI: 10.1016/J.Ygyno.2005.08.042  0.794
2006 Noureddini SC, Curiel DT. Genetic targeting strategies for adenovirus. Molecular Pharmaceutics. 2: 341-7. PMID 16196486 DOI: 10.1021/Mp050045C  0.465
2006 Hedley SJ, Auf der Maur A, Hohn S, Escher D, Barberis A, Glasgow JN, Douglas JT, Korokhov N, Curiel DT. An adenovirus vector with a chimeric fiber incorporating stabilized single chain antibody achieves targeted gene delivery. Gene Therapy. 13: 88-94. PMID 16107860 DOI: 10.1038/Sj.Gt.3302603  0.464
2006 Gommans WM, van Eert SJ, McLaughlin PM, Harmsen MC, Yamamoto M, Curiel DT, Haisma HJ, Rots MG. The carcinoma-specific epithelial glycoprotein-2 promoter controls efficient and selective gene expression in an adenoviral context. Cancer Gene Therapy. 13: 150-8. PMID 16096650 DOI: 10.1038/Sj.Cgt.7700882  0.651
2006 Yamamoto M, Nishimoto N, Davydova J, Kishimoto T, Curiel DT. Suppressor of cytokine signaling-1 expression by infectivity-enhanced adenoviral vector inhibits IL-6-dependent proliferation of multiple myeloma cells. Cancer Gene Therapy. 13: 194-202. PMID 16082380 DOI: 10.1038/Sj.Cgt.7700873  0.344
2006 Rots MG, Elferink MG, Gommans WM, Oosterhuis D, Schalk JA, Curiel DT, Olinga P, Haisma HJ, Groothuis GM. An ex vivo human model system to evaluate specificity of replicating and non-replicating gene therapy agents. The Journal of Gene Medicine. 8: 35-41. PMID 16044485 DOI: 10.1002/Jgm.815  0.595
2006 Grill J, Lamfers ML, van Beusechem VW, van der Valk P, Huisman A, Sminia P, Alemany R, Curiel DT, Vandertop WP, Gerritsen WR, Dirven CM. Oncolytic virotherapy of meningiomas in vitro with replication-competent adenovirus. Neurosurgery. 56: 146-53; discussion 1. PMID 15617597 DOI: 10.1227/01.Neu.0000146207.55774.69  0.366
2006 Chen J, Hsu H-, Zajac A, Wu Q, Yang P-, Xu X, Curiel DT, Mountz JD. 152 IN VIVO ANALYSIS OF THE ADENOVIRUS-SPECIFIC CYTOTOXIC T-LYMPHOCYTE RESPONSE IN CD28-, FASL-, AND PERFORIN-DEFICIENT MICE. Journal of Investigative Medicine. 54: S283.1-S283. DOI: 10.2310/6650.2005.X0008.129  0.343
2006 Tsuruta Y, Pereboeva L, Rein DT, Breidenbach M, Curiel DT. Therapeutic efficacy of an oncolytic adenovirus monitored by in vivo imaging of an ovarian cancer model Journal of Clinical Oncology. 24: 10061-10061. DOI: 10.1200/Jco.2006.24.18_Suppl.10061  0.49
2006 Zhu ZB, Makhija SK, Lu B, Wang M, Kaliberova L, Liu B, Rivera AA, Nettelbeck DM, Mahasreshti PJ, Leath CA, Yamaoto M, Alvarez RD, Curiel DT. Erratum: Transcriptional targeting of adenoviral vector through the CXCR4 tumor-specific promoter Gene Therapy. 13: 374-374. DOI: 10.1038/Sj.Gt.3302731  0.382
2006 Zhu ZB, Makhija SK, Lu B, Wang M, Wang S, Takayama K, Siegal GP, Reynolds PN, Curiel DT. Targeting Mesothelioma Using an Infectivity Enhanced Survivin-Conditionally Replicative Adenoviruses Journal of Thoracic Oncology. 1: 701-711. DOI: 10.1016/S1556-0864(15)30385-3  0.454
2006 Davydova J, Nelson AR, Gavrikova T, Le LP, Ono HA, Curiel DT, Yamamoto M. 853. Monitoring of Promoter-Controlled Adenoviral Replication with Noninvasive Imaging in Lung Cancer Molecular Therapy. 13: S329. DOI: 10.1016/J.Ymthe.2006.08.939  0.434
2006 Sibley DA, Barlow S, DeBenedetti R, Curiel DT, Mathis JM. 843. MicroPET Imaging of HSV-TK Activity To Assess Cancer-Specific Gene Expression Targeted at the Level of Protein Translation Initiation Molecular Therapy. 13: S326. DOI: 10.1016/J.Ymthe.2006.08.929  0.486
2006 Mody DA, Pereboev AV, Sibley DA, Curiel DT, Mathis JM. 836. Changes in Maturation Profiles of Dendritic Cells Transduced with a CD40-Targeted Adenoviral Vector Molecular Therapy. 13: S323. DOI: 10.1016/J.Ymthe.2006.08.922  0.419
2006 Tsuruta Y, Pereboeva L, Breidenbach M, Rein DT, Nakayama M, Siegal GP, Curiel DT. 304. Therapeutic Efficacy of a Mesothelin Promoter-Based Conditionally Replicative Adenovirus Monitored by In Vivo Imaging of an Ovarian Cancer Model Molecular Therapy. 13: S116. DOI: 10.1016/J.Ymthe.2006.08.359  0.485
2006 Nakayama M, Glasgow JN, Smith BF, Li J, Korokhov N, Belousova N, Tani K, Curiel DT. 131. Design and Construction of an Adenovirus Vector Containing Fiber Fibritin/Canine CD40L Fibers Directed to Canine CD40-Expressing Cells Molecular Therapy. 13: S53. DOI: 10.1016/J.Ymthe.2006.08.152  0.477
2006 Chen J, Wu Q, Zajac AJ, Yang P, Xu X, Hsu H, Curiel DT, Mountz JD. 990. In Vivo Analysis of Adenovirus Specific Cytotoxic T Lymphocyte Response in CD28, PD-1, Fas Ligand or Perforin Deficient Mice Molecular Therapy. 13: S381. DOI: 10.1016/J.Ymthe.2006.08.1083  0.354
2006 Aoki K, Miura Y, Yoshida K, Hatanaka K, Nishimoto T, Ohnami S, Douglas JT, Curiel DT, Yoshida T. 16. Direct Selection of Targeted Vector from a Random Peptide Library Displayed on Adenoviral Fiber Knob Molecular Therapy. 13: S7. DOI: 10.1016/J.Ymthe.2006.08.027  0.415
2006 Kawakami Y, Curiel DT. Vector Targeting in Gene Therapy Reviews in Cell Biology and Molecular Medicine. DOI: 10.1002/3527600906.Mcb.200500036  0.448
2005 Stoff-Khalili MA, Stoff A, Rivera AA, Banerjee NS, Everts M, Young S, Siegal GP, Richter DF, Wang M, Dall P, Mathis JM, Zhu ZB, Curiel DT. Preclinical evaluation of transcriptional targeting strategies for carcinoma of the breast in a tissue slice model system. Breast Cancer Research : Bcr. 7: R1141-52. PMID 16457694 DOI: 10.1186/Bcr1353  0.405
2005 Passineau MJ, Siegal GP, Everts M, Pereboev A, Jhala D, Wang M, Zhu ZB, Park SK, Curiel DT, Nelson GM. The natural history of a novel, systemic, disseminated model of syngeneic mouse B-cell lymphoma. Leukemia & Lymphoma. 46: 1627-1638. PMID 16334907 DOI: 10.1080/10428190500221454X  0.376
2005 Mathis JM, Stoff-Khalili MA, Curiel DT. Oncolytic adenoviruses - selective retargeting to tumor cells. Oncogene. 24: 7775-91. PMID 16299537 DOI: 10.1038/Sj.Onc.1209044  0.44
2005 Le LP, Li J, Ternovoi VV, Siegal GP, Curiel DT. Fluorescently tagged canine adenovirus via modification with protein IX-enhanced green fluorescent protein. The Journal of General Virology. 86: 3201-3208. PMID 16298964 DOI: 10.1099/Vir.0.80968-0  0.352
2005 Stoff-Khalili MA, Stoff A, Rivera AA, Mathis JM, Everts M, Wang M, Kawakami Y, Waehler R, Mathews QL, Yamamoto M, Rocconi RP, Siegal GP, Richter DF, Dall P, Zhu ZB, ... Curiel DT, et al. Gene transfer to carcinoma of the breast with fiber-modified adenoviral vectors in a tissue slice model system. Cancer Biology & Therapy. 4: 1203-10. PMID 16177567 DOI: 10.4161/Cbt.4.11.2084  0.465
2005 Izumi M, Kawakami Y, Glasgow JN, Belousova N, Everts M, Kim-Park S, Yamamoto S, Wang M, Le LP, Reynolds PN, Curiel DT. In vivo analysis of a genetically modified adenoviral vector targeted to human CD40 using a novel transient transgenic model. The Journal of Gene Medicine. 7: 1517-25. PMID 16170831 DOI: 10.1002/Jgm.806  0.405
2005 Tsuruta Y, Pereboeva L, Glasgow JN, Luongo CL, Komarova S, Kawakami Y, Curiel DT. Reovirus sigma1 fiber incorporated into adenovirus serotype 5 enhances infectivity via a CAR-independent pathway. Biochemical and Biophysical Research Communications. 335: 205-14. PMID 16061208 DOI: 10.1016/J.Bbrc.2005.07.054  0.417
2005 Stoff-Khalili MA, Rivera AA, Glasgow JN, Le LP, Stoff A, Everts M, Tsuruta Y, Kawakami Y, Bauerschmitz GJ, Mathis JM, Pereboeva L, Seigal GP, Dall P, Curiel DT. A human adenoviral vector with a chimeric fiber from canine adenovirus type 1 results in novel expanded tropism for cancer gene therapy. Gene Therapy. 12: 1696-706. PMID 16034451 DOI: 10.1038/Sj.Gt.3302588  0.515
2005 Yamamoto M, Curiel DT. Cancer gene therapy. Technology in Cancer Research & Treatment. 4: 315-30. PMID 16029053 DOI: 10.1177/153303460500400402  0.406
2005 Li J, Le L, Sibley DA, Mathis JM, Curiel DT. Genetic incorporation of HSV-1 thymidine kinase into the adenovirus protein IX for functional display on the virion. Virology. 338: 247-58. PMID 15996701 DOI: 10.1016/J.Ymthe.2005.06.028  0.363
2005 Zhu ZB, Makhija SK, Lu B, Wang M, Rivera AA, Kim-Park S, Ulasov IV, Zhou F, Alvarez RD, Siegal GP, Curiel DT. Incorporating the survivin promoter in an infectivity enhanced CRAd-analysis of oncolysis and anti-tumor effects in vitro and in vivo. International Journal of Oncology. 27: 237-46. PMID 15942665  0.345
2005 Korokhov N, Noureddini SC, Curiel DT, Santegoets SJ, Scheper RJ, de Gruijl TD. A single-component CD40-targeted adenovirus vector displays highly efficient transduction and activation of dendritic cells in a human skin substrate system. Molecular Pharmaceutics. 2: 218-23. PMID 15934782 DOI: 10.1021/Mp050002W  0.403
2005 Dent P, Yacoub A, Grant S, Curiel DT, Fisher PB. MDA-7/IL-24 regulates proliferation, invasion and tumor cell radiosensitivity: A new cancer therapy? Journal of Cellular Biochemistry. 95: 712-719. PMID 15880678 DOI: 10.1002/Jcb.20502  0.349
2005 Uchino J, Takayama K, Harada A, Kawakami Y, Inoue H, Curiel DT, Nakanishi Y. Infectivity enhanced, hTERT promoter-based conditionally replicative adenoviruses are useful for SCLC treatment. Cancer Gene Therapy. 12: 737-48. PMID 15861179 DOI: 10.1038/Sj.Cgt.7700838  0.455
2005 Tekant Y, Davydova J, Ramirez PJ, Curiel DT, Vickers SM, Yamamoto M. Oncolytic adenoviral therapy in gallbladder carcinoma. Surgery. 137: 527-35. PMID 15855925 DOI: 10.1016/J.Surg.2004.12.014  0.411
2005 Everts M, Kim-Park SA, Preuss MA, Passineau MJ, Glasgow JN, Pereboev AV, Mahasreshti PJ, Grizzle WE, Reynolds PN, Curiel DT. Selective induction of tumor-associated antigens in murine pulmonary vasculature using double-targeted adenoviral vectors. Gene Therapy. 12: 1042-8. PMID 15789059 DOI: 10.1038/sj.gt.3302491  0.32
2005 Korokhov N, de Gruijl TD, Aldrich WA, Triozzi PL, Banerjee PT, Gillies SD, Curiel TJ, Douglas JT, Scheper RJ, Curiel DT. High efficiency transduction of dendritic cells by adenoviral vectors targeted to DC-SIGN. Cancer Biology & Therapy. 4: 289-94. PMID 15753654 DOI: 10.4161/Cbt.4.3.1499  0.399
2005 Wu H, Han T, Belousova N, Krasnykh V, Kashentseva E, Dmitriev I, Kataram M, Mahasreshti PJ, Curiel DT. Identification of sites in adenovirus hexon for foreign peptide incorporation. Journal of Virology. 79: 3382-90. PMID 15731232 DOI: 10.1128/Jvi.79.6.3382-3390.2005  0.709
2005 Rein DT, Breidenbach M, Kirby TO, Han T, Siegal GP, Bauerschmitz GJ, Wang M, Nettelbeck DM, Tsuruta Y, Yamamoto M, Dall P, Hemminki A, Curiel DT. A fiber-modified, secretory leukoprotease inhibitor promoter-based conditionally replicating adenovirus for treatment of ovarian cancer Clinical Cancer Research. 11: 1327-1335. PMID 15709205  0.401
2005 Borovjagin AV, Krendelchtchikov A, Ramesh N, Yu DC, Douglas JT, Curiel DT. Complex mosaicism is a novel approach to infectivity enhancement of adenovirus type 5-based vectors. Cancer Gene Therapy. 12: 475-86. PMID 15706356 DOI: 10.1038/Sj.Cgt.7700806  0.456
2005 Lu B, Makhija SK, Nettelbeck DM, Rivera AA, Wang M, Komarova S, Zhou F, Yamamoto M, Haisma HJ, Alvarez RD, Curiel DT, Zhu ZB. Evaluation of tumor-specific promoter activities in melanoma. Gene Therapy. 12: 330-8. PMID 15696177 DOI: 10.1038/Sj.Gt.3302385  0.666
2005 Ono HA, Davydova JG, Adachi Y, Takayama K, Barker SD, Reynolds PN, Krasnykh VN, Kunisaki C, Shimada H, Curiel DT, Yamamoto M. Promoter-controlled infectivity-enhanced conditionally replicative adenoviral vectors for the treatment of gastric cancer. Journal of Gastroenterology. 40: 31-42. PMID 15692787 DOI: 10.1007/S00535-004-1490-Y  0.738
2005 Engesaeter BØ, Bonsted A, Berg K, Høgset A, Engebråten O, Fodstad Ø, Curiel DT, Maelandsmo GM. PCI-enhanced adenoviral transduction employs the known uptake mechanism of adenoviral particles. Cancer Gene Therapy. 12: 439-48. PMID 15678152 DOI: 10.1038/Sj.Cgt.7700808  0.461
2005 Wang M, Hemminki A, Siegal GP, Barnes MN, Dmitriev I, Krasnykh V, Liu B, Curiel DT, Alvarez RD. Adenoviruses with an RGD-4C modification of the fiber knob elicit a neutralizing antibody response but continue to allow enhanced gene delivery. Gynecologic Oncology. 96: 341-8. PMID 15661219 DOI: 10.1016/J.Ygyno.2004.09.063  0.373
2005 Ternovoi VV, Le LP, Belousova N, Smith BF, Siegal GP, Curiel DT. Productive replication of human adenovirus type 5 in canine cells. Journal of Virology. 79: 1308-11. PMID 15613357 DOI: 10.1128/Jvi.79.2.1308-1311.2005  0.414
2005 Pereboeva L, Curiel DT. Cellular vehicles for cancer gene therapy: current status and future potential. Biodrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. 18: 361-85. PMID 15571421 DOI: 10.2165/00063030-200418060-00003  0.48
2005 Breidenbach M, Rein DT, Everts M, Glasgow JN, Wang M, Passineau MJ, Alvarez RD, Korokhov N, Curiel DT. Mesothelin-mediated targeting of adenoviral vectors for ovarian cancer gene therapy. Gene Therapy. 12: 187-93. PMID 15526007 DOI: 10.1038/Sj.Gt.3302404  0.495
2005 Lam JT, Kanerva A, Bauerschmitz GJ, Takayama K, Suzuki K, Yamamoto M, Bhoola SM, Liu B, Wang M, Barnes MN, Alvarez RD, Siegal GP, Curiel DT, Hemminki A. Inter-patient variation in efficacy of five oncolytic adenovirus candidates for ovarian cancer therapy. The Journal of Gene Medicine. 6: 1333-42. PMID 15493039 DOI: 10.1002/Jgm.635  0.464
2005 Kanerva A, Zinn KR, Peng KW, Ranki T, Kangasniemi L, Chaudhuri TR, Desmond RA, Wang M, Takayama K, Hakkarainen T, Alfthan H, Stenman UH, Curiel DT, Hemminki A. Noninvasive dual modality in vivo monitoring of the persistence and potency of a tumor targeted conditionally replicating adenovirus. Gene Therapy. 12: 87-94. PMID 15385953 DOI: 10.1038/sj.gt.3302387  0.305
2005 Volk AL, Rivera AA, Page GP, Salazar-Gonzalez JF, Nettelbeck DM, Matthews QL, Curiel DT. Employment of microarray analysis to characterize biologic differences associated with tropism-modified adenoviral vectors: utilization of non-native cellular entry pathways. Cancer Gene Therapy. 12: 162-74. PMID 15375380 DOI: 10.1038/Sj.Cgt.7700776  0.431
2005 Mahendra G, Kumar S, Isayeva T, Mahasreshti PJ, Curiel DT, Stockardt CR, Grizzle WE, Alapati V, Singh R, Siegal GP, Meleth S, Ponnazhagan S. Antiangiogenic cancer gene therapy by adeno-associated virus 2-mediated stable expression of the soluble FMS-like tyrosine kinase-1 receptor. Cancer Gene Therapy. 12: 26-34. PMID 15359287 DOI: 10.1038/Sj.Cgt.7700754  0.449
2005 Pereboeva L, Komarova S, Mahasreshti PJ, Curiel DT. Fiber-mosaic adenovirus as a novel approach to design genetically modified adenoviral vectors. Virus Research. 105: 35-46. PMID 15325079 DOI: 10.1016/J.Virusres.2004.04.012  0.308
2005 Haviv YS, van Houdt WJ, Lu B, Curiel DT, Zhu ZB. Transcriptional targeting in renal cancer cell lines via the human CXCR4 promoter. Molecular Cancer Therapeutics. 3: 687-91. PMID 15210854  0.35
2005 Ferrer M, de Winter JP, Mastenbroek DC, Curiel DT, Gerritsen WR, Giaccone G, Kruyt FA. Chemosensitizing tumor cells by targeting the Fanconi anemia pathway with an adenovirus overexpressing dominant-negative FANCA. Cancer Gene Therapy. 11: 539-46. PMID 15192709 DOI: 10.1038/Sj.Cgt.7700734  0.449
2005 Zhu ZB, Makhija SK, Lu B, Wang M, Rivera AA, Kim-Park S, Ulasov IV, Zhou F, Alvarez RD, Siegal GP, Curiel DT. Incorporating the survivin promoter in an infectivity enhanced CRAd-analysis of oncolysis and anti-tumor effects in vitro and in vivo International Journal of Oncology. 27: 237-246. DOI: 10.3892/Ijo.27.1.237  0.453
2005 Rein D, Breidenbach M, Bauerschmitz G, Nettelbeck D, Curiel D, Dall P. Gene Therapy for ovarian cancer via a novel fiber modified conditionally replicating Adenovirus Zentralblatt FüR GynäKologie. 127. DOI: 10.1055/S-2005-921026  0.391
2005 Breidenbach M, Rimbach S, Rath W, Curiel DT, Rein DT. A novel transcriptional targeting strategy for breast cancer gene therapy Geburtshilfe Und Frauenheilkunde. 65: 186-191. DOI: 10.1055/S-2005-837498  0.382
2005 Korokhov N, Noureddini SC, Curiel DT, Santegoets SJAM, Scheper RJ, Gruijl TDd. 1130. A Single-Component CD40-Targeted Adenoviral Vector for Efficient Transduction and Activation of Cutaneous Dendritic Cells Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.678  0.427
2005 Kawakami Y, Rivera AA, Wang M, Nettelbeck DM, Stoff-Khalili MA, Barnes MN, Siegal GP, Alvarez RD, Curiel DT. 1029. Integrin and Serotype 3 Receptor-Targeted Virotherapy Using a Telomerase-Selective Oncolytic Adenovirus Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.576  0.489
2005 Särkioja M, Kanerva A, Hakkarainen T, Salo J, Kangasniemi L, Raki M, Ranki T, Wu H, Curiel DT, Hemminki A. 1026. In Vivo Imaging for Evaluation of Adenoviral Capsid Modifications for Systemic Delivery in an Orthotopic Model of Locally Advanced Lung Cancer Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.573  0.747
2005 Davydova J, Ono HA, Le LP, Gavrikova T, Yamamoto S, Nelson AR, Curiel DT, Yamamoto M. 1020. Noninvasive Optical Monitoring of Conditionally Replivative Adenovirus Replication Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.567  0.39
2005 Stoff-Khalili MA, Rivera AA, Glasgow JN, Le LP, Stoff A, Everts M, Tsuruta Y, Kawakami Y, Mathis JM, Pereboeva L, Dall P, Curiel DT. 1018. Infectivity Enhancement for Ovarian Cancer and Glioma Via a Novel Human Adenoviral Vector with a Chimeric Fiber Derived from Canine Adenovirus Type 1 Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.565  0.517
2005 Everts M, Kim-Park S, Preuss MA, Passineau MJ, Glasgow JN, Pereboev AV, Mahasreshti PJ, Grizzle WE, Reynolds PN, Curiel DT. 1017. Selective Induction of Tumor-Associated Antigens in Murine Pulmonary Vasculature Using Double-Targeted Adenoviral Vectors Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.564  0.433
2005 Schierer S, Kosmides D, Rivera AA, Hesse A, Mainka A, Volk AL, Schuler G, Curiel DT, Nettelbeck DM. 1007. Genetic Strategies to Improve Oncolytic Adenoviruses for Targeted and Efficient Virotherapy of Malignant Melanoma Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.554  0.419
2005 Nakayama M, Glasgow JN, Both GW, Palmarini M, Tsuruta Y, Tani K, Douglas JT, Curiel DT. 886. An Adenovirus Vector with a Chimeric Fiber Derived from Ovine Adenovirus for Novel Tropism Discovery Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.429  0.499
2005 Everts M, Leddon JL, Kok RJ, Preuss MA, Millican CL, Nikles DE, Johnson DT, Curiel DT. 883. Gold Nanoparticles as an Amplifying Payload Strategy for Adenoviral Cancer Gene Therapy Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.426  0.383
2005 Glasgow JN, Kashentseva E, Dmitriev IP, Curiel DT. 873. Adenovirus Polypeptide IIIa as a Novel Locale for Incorporation of Heterologous Peptides Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.416  0.428
2005 Reynolds AM, Holmes MD, Curiel DT, Baker AH, Reynolds PN. 811. ACE-Targeted eNOS and BMPR2 Gene Therapy Attenuates Pulmonary Hypertension in a Chronic Hypoxia Rat Model Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.348  0.379
2005 Adachi Y, Yoshio N, Aoki C, Pereboev A, Curiel DT, Yamamoto M, Nishimoto N. 679. Establishment of New IL-6 Receptor Inhibitor Applicable to the Gene Therapy Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.219  0.322
2005 Pereboeva L, Komarova S, Ponnazhagan S, Curiel DT. 542. Targeting EGFR with Metabolically Biotinylated Fiber-Mosaic Adenovirus Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.082  0.386
2005 Everts M, Li J, Pondugula K, Rivera AA, Curiel DT, Mathis JM. 540. Re-Targeting of Adenoviral Vector-Mediated Interferon-|[gamma]| Gene Transfer to Colon Cancer Cells That Express the Human Carcinoembryonic Antigen Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.080  0.46
2005 Zhu ZB, Houdt WJ, Haviv YS, Lu B, Wang M, Rivera AA, Ulasov IV, Lesniak MS, Siegal GP, Dirven CMF, Curiel DT. 537. Transcriptionally Targeting the Survivin Promoter to Human Gliomas Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.077  0.493
2005 Tsuruta Y, Pereboeva L, Glasgow JN, Kawakami Y, Curiel DT. 528. Infectivity Enhancement of a Genetic Fiber Mosaic Adenovirus Vector in Ovarian Cancer Cells Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.068  0.489
2005 Ranki T, Kanerva A, Smitten Kv, Sarkioja M, Kangasniemi L, Raki M, Laakkonen P, Wu H, Curiel DT, Goodison S, Hemminki A. 328. An Orthotopic Murine Model of Advanced Breast Cancer for Imaging and Comparison of Targeting Moieties Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.331  0.749
2005 Uchino J, Takayama k, Sone T, Harada a, Harada T, Curiel DT, Nakanishi Y. 322. Tumor Specific Activation of Irinotecan by a Carboxylesterase Fused with Anti CEA scFv Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.325  0.4
2005 Williams BJ, Korokhov N, Boling S, Li L, Mathis M, Curiel DT. 316. Dendritic Cell-Based Genetic Immunotherapy for Prostate Cancer Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.319  0.472
2005 Gommans WM, Duns G, McLaughlin PMJ, Eert SJv, Yamamoto M, Curiel DT, Haisma HJ, Rots MG. 314. The Epithelial Glycoprotein-2 Promoter for Highly Specific and Efficient Cancer Gene Therapy for a Broad Range of Tumors Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.317  0.68
2005 Kangasniemi L, Kanerva A, Raki M, Ranki T, Sarkioja M, Kiviluoto T, Stenman U, Alfthan H, Wu H, Curiel DT, Hemminki A. 299. Increasing Gene Transfer and Oncolytic Potency of Adenoviruses in Orthotopic Models of Gastric Cancer Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.302  0.748
2005 Chen J, Zajac AJ, McPherson SA, Xu X, Yang P, Wu Q, Curiel DT, Mountz JD. 140. Primary Adenovirus Specific Cytotoxic T Lymphocyte Response Occurs after Viral Clearance and Liver Enzyme Elevation Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.145  0.4
2005 Glasgow JN, Korokhov N, Curiel DT. 28. Adenovirus Targeting Via Leucine Zipper Peptide-Mediated Ligand Attachment Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.040  0.479
2005 Noureddini SC, Krendelshchikov A, Simonenko V, Douglas JT, Curiel DT, Korokhov N. 30. AdenoLibrary for Construction and Selection of Targeted Adenoviruses Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.032  0.409
2004 Arafat WO, Rein D, Buchsbaum D, Curiel D, Zhu Z. Survivin as a novel radiation/CIS platinum/tumor specific promoter for conditional oncolytic viral therapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 1535. PMID 28015408 DOI: 10.1200/Jco.2004.22.14_Suppl.1535  0.647
2004 Stoff-Khalili MA, Dall P, Curiel DT. From gene therapy to virotherapy for ovarian cancer. Minerva Ginecologica. 56: 503-14. PMID 15729203  0.338
2004 Kirby TO, Rivera A, Rein D, Wang M, Ulasov I, Breidenbach M, Kataram M, Contreras JL, Krumdieck C, Yamamoto M, Rots MG, Haisma HJ, Alvarez RD, Mahasreshti PJ, Curiel DT. A novel ex vivo model system for evaluation of conditionally replicative adenoviruses therapeutic efficacy and toxicity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 8697-703. PMID 15623655 DOI: 10.1158/1078-0432.Ccr-04-1166  0.598
2004 Liang Q, Yamamoto M, Curiel DT, Herschman HR. Noninvasive imaging of transcriptionally restricted transgene expression following intratumoral injection of an adenovirus in which the COX-2 promoter drives a reporter gene. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 6: 395-404. PMID 15564150 DOI: 10.1016/J.Mibio.2004.09.002  0.431
2004 Liang Q, Dmitriev I, Kashentseva E, Curiel DT, Herschman HR. Noninvasive of adenovirus tumor retargeting in living subjects by a soluble adenovirus receptor-epidermal growth factor (sCAR-EGF) fusion protein. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 6: 385-94. PMID 15564149 DOI: 10.1016/J.Mibio.2004.09.001  0.368
2004 Rivera AA, Davydova J, Schierer S, Wang M, Krasnykh V, Yamamoto M, Curiel DT, Nettelbeck DM. Combining high selectivity of replication with fiber chimerism for effective adenoviral oncolysis of CAR-negative melanoma cells Gene Therapy. 11: 1694-1702. PMID 15496964 DOI: 10.1038/Sj.Gt.3302346  0.488
2004 Everts M, Curiel DT. Transductional targeting of adenoviral cancer gene therapy. Current Gene Therapy. 4: 337-46. PMID 15384947 DOI: 10.2174/1566523043346372  0.414
2004 Lee CT, Park KH, Yanagisawa K, Adachi Y, Ohm JE, Nadaf S, Dikov MM, Curiel DT, Carbone DP. Combination therapy with conditionally replicating adenovirus and replication defective adenovirus. Cancer Research. 64: 6660-5. PMID 15374981 DOI: 10.1158/0008-5472.Can-04-1200  0.431
2004 Rein DT, Breidenbach M, Nettelbeck DM, Kawakami Y, Siegal GP, Huh WK, Wang M, Hemminki A, Bauerschmitz GJ, Yamamoto M, Adachi Y, Takayama K, Dall P, Curiel DT. Evaluation of tissue-specific promoters in carcinomas of the cervix uteri Journal of Gene Medicine. 6: 1281-1289. PMID 15368588 DOI: 10.1002/Jgm.606  0.467
2004 Contreras JL, Xie D, Mays J, Smyth CA, Eckstein C, Rahemtulla FG, Young CJ, Anthony Thompson J, Bilbao G, Curiel DT, Eckhoff DE. A novel approach to xenotransplantation combining surface engineering and genetic modification of isolated adult porcine islets. Surgery. 136: 537-47. PMID 15349100 DOI: 10.1016/J.Surg.2004.05.031  0.32
2004 Leath CA, Kataram M, Bhagavatula P, Gopalkrishnan RV, Dent P, Fisher PB, Pereboev A, Carey D, Lebedeva IV, Haisma HJ, Alvarez RD, Curiel DT, Mahasreshti PJ. Infectivity enhanced adenoviral-mediated mda-7/IL-24 gene therapy for ovarian carcinoma. Gynecologic Oncology. 94: 352-62. PMID 15297172 DOI: 10.1016/J.Ygyno.2004.04.028  0.658
2004 Le LP, Everts M, Dmitriev IP, Davydova JG, Yamamoto M, Curiel DT. Fluorescently labeled adenovirus with pIX-EGFP for vector detection. Molecular Imaging. 3: 105-16. PMID 15296675 DOI: 10.1162/1535350041464874  0.394
2004 Rein DT, Breidenbach M, Wu H, Han T, Haviv YS, Wang M, Kirby TO, Kawakami Y, Dall P, Alvarez RD, Curiel DT. Gene transfer to cervical cancer with fiber-modified adenoviruses. International Journal of Cancer. Journal International Du Cancer. 111: 698-704. PMID 15252838 DOI: 10.1002/Ijc.20295  0.752
2004 Zhu ZB, Makhija SK, Lu B, Wang M, Rivera AA, Preuss M, Zhou F, Siegal GP, Alvarez RD, Curiel DT. Transport across a polarized monolayer of Caco-2 cells by transferrin receptor-mediated adenovirus transcytosis. Virology. 325: 116-28. PMID 15231391 DOI: 10.1016/J.Virol.2004.04.021  0.371
2004 Bauerschmitz GJ, Kanerva A, Wang M, Herrmann I, Shaw DR, Strong TV, Desmond R, Rein DT, Dall P, Curiel DT, Hemminki A. Evaluation of a selectively oncolytic adenovirus for local and systemic treatment of cervical cancer. International Journal of Cancer. 111: 303-9. PMID 15197787 DOI: 10.1002/Ijc.20217  0.41
2004 Yacoub A, Mitchell C, Hong Y, Gopalkrishnan RV, Su ZZ, Gupta P, Sauane M, Lebedeva IV, Curiel DT, Mahasreshti PJ, Rosenfeld MR, Broaddus WC, James CD, Grant S, Fisher PB, et al. MDA-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells. Cancer Biology & Therapy. 3: 739-51. PMID 15197348 DOI: 10.4161/Cbt.3.8.968  0.368
2004 Glasgow JN, Kremer EJ, Hemminki A, Siegal GP, Douglas JT, Curiel DT. An adenovirus vector with a chimeric fiber derived from canine adenovirus type 2 displays novel tropism. Virology. 324: 103-16. PMID 15183058 DOI: 10.1016/J.Virol.2004.03.028  0.457
2004 Breidenbach M, Rein DT, Wang M, Nettelbeck DM, Hemminki A, Ulasov I, Rivera AR, Everts M, Alvarez RD, Douglas JT, Curiel DT. Genetic replacement of the adenovirus shaft fiber reduces liver tropism in ovarian cancer gene therapy. Human Gene Therapy. 15: 509-18. PMID 15144580 DOI: 10.1089/10430340460745829  0.452
2004 Bonner JA, Buchsbaum DJ, Russo SM, Fiveash JB, Trummell HQ, Curiel DT, Raisch KP. Anti-EGFR-mediated radiosensitization as a result of augmented EGFR expression. International Journal of Radiation Oncology, Biology, Physics. 59: 2-10. PMID 15142629 DOI: 10.1016/J.Ijrobp.2004.01.053  0.5
2004 Preuss MA, Lam JT, Wang M, Leath CA, Kataram M, Mahasreshti PJ, Alvarez RD, Curiel DT. Transcriptional blocks limit adenoviral replication in primary ovarian tumor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 3189-94. PMID 15131060 DOI: 10.1158/1078-0432.Ccr-03-0802  0.408
2004 Pereboev AV, Nagle JM, Shakhmatov MA, Triozzi PL, Matthews QL, Kawakami Y, Curiel DT, Blackwell JL. Enhanced gene transfer to mouse dendritic cells using adenoviral vectors coated with a novel adapter molecule. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 712-20. PMID 15120332 DOI: 10.1016/J.Ymthe.2004.02.006  0.464
2004 Short JJ, Pereboev AV, Kawakami Y, Vasu C, Holterman MJ, Curiel DT. Adenovirus serotype 3 utilizes CD80 (B7.1) and CD86 (B7.2) as cellular attachment receptors. Virology. 322: 349-59. PMID 15110532 DOI: 10.1016/J.Virol.2004.02.016  0.684
2004 Verwijnen SM, Sillevis Smith PA, Hoeben RC, Rabelink MJ, Wiebe L, Curiel DT, Hemminki A, Krenning EP, de Jong M. Molecular imaging and treatment of malignant gliomas following adenoviral transfer of the herpes simplex virus-thymidine kinase gene and the somatostatin receptor subtype 2 gene. Cancer Biotherapy & Radiopharmaceuticals. 19: 111-20. PMID 15068619 DOI: 10.1089/108497804773391757  0.478
2004 Glasgow JN, Bauerschmitz GJ, Curiel DT, Hemminki A. Transductional and transcriptional targeting of adenovirus for clinical applications. Current Gene Therapy. 4: 1-14. PMID 15032610 DOI: 10.2174/1566523044577997  0.449
2004 Zhu ZB, Makhija SK, Lu B, Wang M, Kaliberova L, Liu B, Rivera AA, Nettelbeck DM, Mahasreshti PJ, Leath CA, Yamamoto M, Yamaoto M, Alvarez RD, Curiel DT. Transcriptional targeting of adenoviral vector through the CXCR4 tumor-specific promoter. Gene Therapy. 11: 645-8. PMID 15029227 DOI: 10.1038/Sj.Gt.3302089  0.476
2004 Zhu ZB, Makhija SK, Lu B, Wang M, Kaliberova L, Liu B, Rivera AA, Nettelbeck DM, Mahasreshti PJ, Leath CA, Barker S, Yamaoto M, Li F, Alvarez RD, Curiel DT. Transcriptional targeting of tumors with a novel tumor-specific survivin promoter. Cancer Gene Therapy. 11: 256-62. PMID 15017380 DOI: 10.1038/Sj.Cgt.7700679  0.764
2004 Leath CA, Douglas JT, Curiel DT, Alvarez RD. Single-chain antibodies: A therapeutic modality for cancer gene therapy (review). International Journal of Oncology. 24: 765-71. PMID 15010813  0.337
2004 Grandi P, Wang S, Schuback D, Krasnykh V, Spear M, Curiel DT, Manservigi R, Breakefield XO. HSV-1 virions engineered for specific binding to cell surface receptors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 419-27. PMID 15006609 DOI: 10.1016/J.Ymthe.2003.12.010  0.41
2004 Rivera AA, Wang M, Suzuki K, Uil TG, Krasnykh V, Curiel DT, Nettelbeck DM. Mode of transgene expression after fusion to early or late viral genes of a conditionally replicating adenovirus via an optimized internal ribosome entry site in vitro and in vivo. Virology. 320: 121-34. PMID 15003868 DOI: 10.1016/J.Virol.2003.11.028  0.425
2004 Wu H, Han T, Lam JT, Leath CA, Dmitriev I, Kashentseva E, Barnes MN, Alvarez RD, Curiel DT. Preclinical evaluation of a class of infectivity-enhanced adenoviral vectors in ovarian cancer gene therapy Gene Therapy. 11: 874-878. PMID 14999229 DOI: 10.1038/Sj.Gt.3302249  0.747
2004 Kanerva A, Bauerschmitz GJ, Yamamoto M, Lam JT, Alvarez RD, Siegal GP, Curiel DT, Hemminki A. A cyclooxygenase-2 promoter-based conditionally replicating adenovirus with enhanced infectivity for treatment of ovarian adenocarcinoma. Gene Therapy. 11: 552-9. PMID 14999227 DOI: 10.1038/Sj.Gt.3302181  0.43
2004 Timares L, Douglas JT, Tillman BW, Krasnykh V, Curiel DT. Adenovirus-mediated gene delivery to dendritic cells. Methods in Molecular Biology (Clifton, N.J.). 246: 139-54. PMID 14970589 DOI: 10.1385/1-59259-650-9:139  0.68
2004 Bonner JA, Buchsbaum DJ, Rogers BE, Grizzle WE, Trummell HQ, Curiel DT, Fiveash JB, Ove R, Raisch KP. Adenoviral vector-mediated augmentation of epidermal growth factor receptor (EGFr) enhances the radiosensitization properties of anti-EGFr treatment in prostate cancer cells. International Journal of Radiation Oncology, Biology, Physics. 58: 950-8. PMID 14967455 DOI: 10.1016/J.Ijrobp.2003.09.095  0.543
2004 Witlox AM, Van Beusechem VW, Molenaar B, Bras H, Schaap GR, Alemany R, Curiel DT, Pinedo HM, Wuisman PI, Gerritsen WR. Conditionally replicative adenovirus with tropism expanded towards integrins inhibits osteosarcoma tumor growth in vitro and in vivo. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 61-7. PMID 14734452 DOI: 10.1158/1078-0432.Ccr-0609-03  0.546
2004 Yamamoto M, Curiel DT. Nonreplicating DNA viral vectors for suicide gene therapy: the adenoviral vectors. Methods in Molecular Medicine. 90: 61-70. PMID 14657559 DOI: 10.1385/1-59259-429-8:61  0.356
2004 Nettelbeck DM, Rivera AA, Kupsch J, Dieckmann D, Douglas JT, Kontermann RE, Alemany R, Curiel DT. Retargeting of adenoviral infection to melanoma: combining genetic ablation of native tropism with a recombinant bispecific single-chain diabody (scDb) adapter that binds to fiber knob and HMWMAA. International Journal of Cancer. Journal International Du Cancer. 108: 136-45. PMID 14618628 DOI: 10.1002/Ijc.11563  0.5
2004 Volk AL, Rivera AA, Kanerva A, Bauerschmitz G, Dmitriev I, Nettelbeck DM, Curiel DT. Enhanced adenovirus infection of melanoma cells by fiber-modification: incorporation of RGD peptide or Ad5/3 chimerism. Cancer Biology & Therapy. 2: 511-5. PMID 14614316 DOI: 10.4161/cbt.2.5.440  0.366
2004 Kirby TO, Curiel DT, Alvarez RD. Gene therapy for ovarian cancer: progress and potential. Hematology/Oncology Clinics of North America. 17: 1021-50. PMID 12959190 DOI: 10.1016/S0889-8588(03)00055-8  0.463
2004 Hemminki A, Wang M, Hakkarainen T, Desmond RA, Wahlfors J, Curiel DT. Production of an EGFR targeting molecule from a conditionally replicating adenovirus impairs its oncolytic potential. Cancer Gene Therapy. 10: 583-8. PMID 12872139 DOI: 10.1038/Sj.Cgt.7700606  0.417
2004 Haviv YS, Curiel DT. Engineering regulatory elements for conditionally-replicative adeno-viruses. Current Gene Therapy. 3: 357-85. PMID 12871022 DOI: 10.2174/1566523034578311  0.474
2004 Pereboeva L, Komarova S, Mikheeva G, Krasnykh V, Curiel DT. Approaches to utilize mesenchymal progenitor cells as cellular vehicles. Stem Cells (Dayton, Ohio). 21: 389-404. PMID 12832693 DOI: 10.1634/Stemcells.21-4-389  0.531
2004 Nettelbeck DM, Rivera AA, Davydova J, Dieckmann D, Yamamoto M, Curiel DT. Cyclooxygenase-2 promoter for tumour-specific targeting of adenoviral vectors to melanoma. Melanoma Research. 13: 287-92. PMID 12777984 DOI: 10.1097/00008390-200306000-00010  0.452
2004 Leath CA, Douglas JT, Curiel DT, Alvarez RD. Single-chain antibodies: A therapeutic modality for cancer gene therapy (review). International Journal of Oncology. 24: 765-771. DOI: 10.3892/Ijo.24.4.765  0.447
2004 Contreras JL, Chaudhuri TR, Stargel AV, Wu H, Smyth C, Bilbao G, Curiel DT, Eckhoff D, Zinn K. IN VIVO QUANTITATIVE NON-INVASIVE BIOLUMINESCENCE IMAGING OF INTRAHEPATIC TRANSPLANTED ISLETS. Transplantation. 78: 439-440. DOI: 10.1097/00007890-200407271-01176  0.6
2004 Zhu ZB, Makhija SK, Lu B, Wang M, Preuss MA, Rivera AA, Zhou F, Siegal GP, Alvarez RD, Curiel DT. 1023. Adenoviruses Transport across a Polarized Monolayer of Caco-2 Cells by Transferrin Receptor-Mediated Transcytosis Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.968  0.461
2004 Gavrikova T, Davydova J, Le LP, Ono HA, Ramirez PJ, Krasnykh V, Curiel DT, Yamamoto M. 971. New Generation Conditionally Replicative Adenovirus for Hormone-Refractory Prostate Cancer Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.914  0.461
2004 Rein DT, Breidenbach M, Wang M, Kirby TO, Siegal GP, Bauerschmitz GJ, Dall P, Nettelbeck DM, Hemminki A, Alvarez RD, Curiel DT. 970. A Fiber Modified SLPI Promoter Based Conditionally Replicating Adenovirus for Treatment of Ovarian Cancer Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.913  0.507
2004 Takayama K, Uchino J, Harada A, Kawakami Y, Curiel DT, Nakanishi Y. 964. Infectivity Enhanced, hTERT Promoter-Based Conditionally Replicative Adenoviruses Are Useful for the Treatment of Small Cell Lung Cancer Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.907  0.431
2004 Kanerva A, Raki M, Bauerschmitz GJ, Takayama K, Yamamoto M, Desmond RA, Curiel DT, Hemminki A. 960. Regulation of Cyclooxygenase-2 and Vascular Endothelial Growth Factor Promoter Based Conditionally Replicating Adenoviruses for Treatment of Cervical Cancer Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.903  0.37
2004 Ono HA, Le LP, Davydova JG, Gavrikova T, Ramirez PJ, Shimada H, Curiel DT, Yamamoto M. 788. Imaging of Adenoviral Replication with a Fluorescent Reporter in the E3 Region Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.878  0.423
2004 Le LP, Dmitriev IP, Davydova JG, Yamamoto M, Curiel DT. Genetic labeling of adenovirus with luciferase on pIX for vector detection Molecular Therapy. 9: 297-298. DOI: 10.1016/J.Ymthe.2004.06.876  0.425
2004 Le LP, Dmitriev IP, Davydova JG, Yamamoto M, Curiel DT. Genetic labeling of adenovirus with red fluorescent proteins on pIX for vector detection Molecular Therapy. 9: 296. DOI: 10.1016/J.Ymthe.2004.06.872  0.373
2004 Kawakami Y, Danilov SM, Reynolds PN, Grunda JM, Passineau M, Balyasnikova IV, Glasgow JN, Wang M, Zhu Z, Triozzi PL, Aldrich WA, Blackwell JL, Curiel DT. 664. Surface-Expressed Angiotensin-Converting Enzyme as a Novel Approach To Target Adenovirus to Dendritic Cells Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.628  0.421
2004 Glasgow JN, Mhashilkar A, Curiel DT, Korokhov N. 662. Adenovirus Targeting Via Leucine Zipper Peptide Ligand Attachment Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.626  0.484
2004 Chen J, McPherson SA, Zajac A, Hsu H, Wu Q, Yang P, Curiel DT, Mountz JD. 644. Decreased Generation and Cytotoxic Function of Adenovirus-Specific CD8 T Cells in Both CD28 and FasL Deficient Mice Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.585  0.362
2004 Chen J, McPherson SA, Zajac A, Hsu H, Wu Q, Yang P, Xu X, Curiel DT, Mountz JD. 640. E1Bp-Specific CD8+ T Lymphocytes Are Highly Induced in the Liver and Spleen Eight Days after Adenoviral Infection Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.578  0.387
2004 Takayama K, Ikegami A, Inoue H, Kaliberova L, Uchino J, Curiel DT, Nakanishi Y. 629. VEGF Promoter-Based Conditionally Replicative Adenoviruses Are Useful for the Treatment of Malignant Pleural Mesothelioma Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.553  0.429
2004 Breidenbach M, Rein DT, Tsuruta Y, Wang M, Herrmann I, Alvarez RD, Reynolds PN, Curiel DT. 623. Transcriptional Targeting of Breast Cancer Employing the Heparanase Promoter Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.547  0.393
2004 Kawakami Y, Takayama K, Yamamoto M, Nettelbeck DM, Wang M, Barnes MN, Siegal GP, Alvarez RD, Curiel DT, Blackwell JL. 620. A Longer Human Telomerase Reverse Transcriptase Promoter-Based Conditionally Replicative Adenovirus Shows Oncolysis with Less Toxicity for Ovarian Cancer Treatment Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.544  0.426
2004 Zhu ZB, Makhija SK, Lu B, Wang M, Rivera AA, Siegal GP, Alvarez RD, Curiel DT. 443. Incorporating the Survivin Promoter in an Infectivity Enhanced CRAd-Analysis of Oncolysis in Five Different Cancer Cell Lines Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.361  0.479
2004 Bauerschmitz GJ, Kanerva A, Yamamoto M, Nettelbeck D, Hakkarainen T, Dall P, Curiel DT, Hemminki A. 442. Novel cox-2 Driven Infectivity Enhanced CRAds for Treatment of Ovarian Cancer Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.358  0.451
2004 Gommans W, Rots M, McLaughlin P, Eert Sv, Harmsen M, Yamamoto M, Curiel D, Haisma H. The epithelial glycoprotein-2 promoter controls selective and efficient killing of epithelium derived cancer cells Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.235  0.64
2004 Graat HCA, Witlox MA, Schagen FHE, Kaspers GJL, Curiel DT, Helder MN, Bras J, Schaap GR, Gerritsen WR, Wuisman PIJM, Beusechem VWv. 289. Cisplatin and Doxorubicin Enhance the Activity of the CRAd Ad5-|[Delta]|24RGD Against Osteosarcoma Cell Lines but Not Primary Osteosarcoma Cells Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.229  0.406
2004 Banerjee PT, Klinz SG, Pereboev AV, Nelson DR, Huston JS, Curiel DT, Gillies SD. 267. Enhancement of T-Cell Immunity by CEA Delivery to Dendritic Cells with Adenovirus Retargeted Via sCAR-Fibritin-CD40L Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.207  0.442
2004 Tsuruta Y, Pereboeva L, Glasgow JN, Luongo CL, Komarova S, Kawakami Y, Curiel DT. 129. Infectivity enhancement of an adenovirus vector via genetic incorporation of the reovirus spike protein sigma 1 Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.085  0.473
2004 Short JJ, Pereboev AV, Kawakami Y, Vasu C, Holterman MJ, Curiel DT. 116. Members of Adenovirus Subgroup B Utilize CD80 (B7.1) and CD86 (B7.2) as Primary Cellular Attachment Receptors Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.082  0.707
2004 Noureddini SC, Korokhov N, Mhashilkar A, Douglas JT, Curiel DT. 126. Zc-Ad Vector: A Novel Immunotargeting Vector with a Modified Fc-binding Domain Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.067  0.452
2004 Korokhov N, Aldrich WA, Krendelchtchikov A, Granelli-Piperno A, Banerjee PT, Gillies SD, Triozzi PL, Mhashilkar AM, Curiel DT. 124. Efficient Transduction and Activation of Dendritic Cells by Adenoviral Vectors Targeted to DC-SIGN Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.065  0.38
2004 Izumi M, Kawakami Y, Glasgow JN, Belousova N, Curiel DT. 122. Expression of hCD40 in the Pulmonary Endothelium Targeted Via a Fiber-Modified Adenovirus Improves Gene Delivery to the Lung Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.063  0.48
2004 Pereboeva L, Komarova S, Curiel DT. 115. Genetic Fiber Mosaic Adenovirus Confers New Properties to Adenoviral Particles Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.052  0.376
2004 Rots MG, Elferink MG, Oosterhuis D, Olinga P, Curiel DT, Haisma HJ, Groothuis GMM. A clinically relevant ex vivo toxicity assay using human liver slices to determine specificity of oncolytic viruses Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.05.051  0.632
2004 Everts M, Kim-Park SA, Le LP, Reynolds PN, Grizzle WE, Curiel DT. 21. Induction of CEA in Pulmonary Vasculature to Study Targeting Strategies for Cancer Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.05.044  0.473
2003 Kawakami Y, Curiel TJ, Curiel DT. Cancer gene therapy and immunotherapy. Cancer Chemotherapy and Biological Response Modifiers. 21: 327-37. PMID 15338753 DOI: 10.1016/S0921-4410(03)21016-4  0.385
2003 Korokhov N, Mikheeva G, Krendelshchikov A, Belousova N, Simonenko V, Krendelshchikova V, Pereboev A, Kotov A, Kotova O, Triozzi PL, Aldrich WA, Douglas JT, Lo KM, Banerjee PT, Gillies SD, ... Curiel DT, et al. Targeting of adenovirus via genetic modification of the viral capsid combined with a protein bridge. Journal of Virology. 77: 12931-40. PMID 14645549 DOI: 10.1128/Jvi.77.24.12931-12940.2003  0.447
2003 Buskens CJ, Marsman WA, Wesseling JG, Offerhaus GJ, Yamamoto M, Curiel DT, Bosma PJ, van Lanschot JJ. A genetically retargeted adenoviral vector enhances viral transduction in esophageal carcinoma cell lines and primary cultured esophageal resection specimens. Annals of Surgery. 238: 815-24; discussion 8. PMID 14631218 DOI: 10.1097/01.Sla.0000098622.47909.C0  0.398
2003 Belousova N, Korokhov N, Krendelshchikova V, Simonenko V, Mikheeva G, Triozzi PL, Aldrich WA, Banerjee PT, Gillies SD, Curiel DT, Krasnykh V. Genetically targeted adenovirus vector directed to CD40-expressing cells. Journal of Virology. 77: 11367-77. PMID 14557622 DOI: 10.1128/Jvi.77.21.11367-11377.2003  0.476
2003 Haviv YS, Takayama K, Nagi PA, Tousson A, Cook W, Wang M, Lam JT, Naito S, Lei X, Carey DE, Curiel DT. Modulation of renal glomerular disease using remote delivery of adenoviral-encoded solubletype II TGF-beta receptor fusion molecule. The Journal of Gene Medicine. 5: 839-51. PMID 14533192 DOI: 10.1002/Jgm.428  0.318
2003 Stam AG, Santegoets SJ, Westers TM, Sombroek CC, Janssen JJ, Tillman BW, van de Loosdrecht AA, Pinedo HM, Curiel DT, Ossenkoppele GJ, Scheper RJ, de Gruijl TD. CD40-targeted adenoviral GM-CSF gene transfer enhances and prolongs the maturation of human CML-derived dendritic cells upon cytokine deprivation. British Journal of Cancer. 89: 1162-5. PMID 14520439 DOI: 10.1038/Sj.Bjc.6601225  0.728
2003 Yamamoto M, Davydova J, Wang M, Siegal GP, Krasnykh V, Vickers SM, Curiel DT. Infectivity enhanced, cyclooxygenase-2 promoter-based conditionally replicative adenovirus for pancreatic cancer. Gastroenterology. 125: 1203-18. PMID 14517802 DOI: 10.1016/S0016-5085(03)01196-X  0.366
2003 Kanerva A, Zinn KR, Chaudhuri TR, Lam JT, Suzuki K, Uil TG, Hakkarainen T, Bauerschmitz GJ, Wang M, Liu B, Cao Z, Alvarez RD, Curiel DT, Hemminki A. Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 449-58. PMID 12946318 DOI: 10.1016/S1525-0016(03)00200-4  0.527
2003 Contreras JL, Wu H, Smyth CA, Eckstein CP, Young CJ, Seki T, Bilbao G, Curiel DT, Eckhoff DE. Double genetic modification of adenovirus fiber with RGD polylysine motifs significantly enhances gene transfer to isolated human pancreatic islets. Transplantation. 76: 252-61. PMID 12865820 DOI: 10.1097/01.Tp.0000066361.02042.Ca  0.722
2003 Mahasreshti PJ, Kataram M, Wang MH, Stockard CR, Grizzle WE, Carey D, Siegal GP, Haisma HJ, Alvarez RD, Curiel DT. Intravenous delivery of adenovirus-mediated soluble FLT-1 results in liver toxicity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 2701-10. PMID 12855650  0.572
2003 Barker SD, Dmitriev IP, Nettelbeck DM, Liu B, Rivera AA, Alvarez RD, Curiel DT, Hemminki A. Combined transcriptional and transductional targeting improves the specificity and efficacy of adenoviral gene delivery to ovarian carcinoma. Gene Therapy. 10: 1198-204. PMID 12833129 DOI: 10.1038/Sj.Gt.3301974  0.778
2003 Takayama K, Reynolds PN, Short JJ, Kawakami Y, Adachi Y, Glasgow JN, Rots MG, Krasnykh V, Douglas JT, Curiel DT. A mosaic adenovirus possessing serotype Ad5 and serotype Ad3 knobs exhibits expanded tropism. Virology. 309: 282-93. PMID 12758175 DOI: 10.1016/S0042-6822(03)00067-9  0.742
2003 Brandão JG, Scheper RJ, Lougheed SM, Curiel DT, Tillman BW, Gerritsen WR, van den Eertwegh AJ, Pinedo HM, Haisma HJ, de Gruijl TD. CD40-targeted adenoviral gene transfer to dendritic cells through the use of a novel bispecific single-chain Fv antibody enhances cytotoxic T cell activation. Vaccine. 21: 2268-72. PMID 12744857 DOI: 10.1016/S0264-410X(03)00050-1  0.809
2003 Noya F, Balagué C, Banerjee NS, Curiel DT, Broker TR, Chow LT. Activation of adenovirus early promoters and lytic phase in differentiated strata of organotypic cultures of human keratinocytes. Journal of Virology. 77: 6533-40. PMID 12743310 DOI: 10.1128/Jvi.77.11.6533-6540.2003  0.362
2003 Fueyo J, Alemany R, Gomez-Manzano C, Fuller GN, Khan A, Conrad CA, Liu TJ, Jiang H, Lemoine MG, Suzuki K, Sawaya R, Curiel DT, Yung WK, Lang FF. Preclinical characterization of the antiglioma activity of a tropism-enhanced adenovirus targeted to the retinoblastoma pathway. Journal of the National Cancer Institute. 95: 652-60. PMID 12734316 DOI: 10.1093/Jnci/95.9.652  0.435
2003 Lam JT, Bauerschmitz GJ, Kanerva A, Barker SD, Straughn JM, Wang M, Barnes MN, Blackwell JL, Siegal GP, Alvarez RD, Curiel DT, Hemminki A. Replication of an integrin targeted conditionally replicating adenovirus on primary ovarian cancer spheroids. Cancer Gene Therapy. 10: 377-87. PMID 12719707 DOI: 10.1038/Sj.Cgt.7700578  0.775
2003 Curiel TJ, Wei S, Dong H, Alvarez X, Cheng P, Mottram P, Krzysiek R, Knutson KL, Daniel B, Zimmermann MC, David O, Burow M, Gordon A, Dhurandhar N, Myers L, ... ... Curiel DT, et al. Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity. Nature Medicine. 9: 562-7. PMID 12704383 DOI: 10.1038/Nm863  0.324
2003 Barker SD, Coolidge CJ, Kanerva A, Hakkarainen T, Yamamoto M, Liu B, Rivera AA, Bhoola SM, Barnes MN, Alvarez RD, Curiel DT, Hemminki A. The secretory leukoprotease inhibitor (SLPI) promoter for ovarian cancer gene therapy. The Journal of Gene Medicine. 5: 300-10. PMID 12692864 DOI: 10.1002/Jgm.341  0.774
2003 Nagi P, Vickers SM, Davydova J, Adachi Y, Takayama K, Barker S, Krasnykh V, Curiel DT, Yamamoto M, Sugerman HJ. Development of a therapeutic adenoviral vector for cholangiocarcinoma combining tumor-restricted gene expression and infectivity enhancement Journal of Gastrointestinal Surgery. 7: 364-371. PMID 12654561 DOI: 10.1016/S1091-255X(02)00437-7  0.757
2003 Kawakami Y, Li H, Lam JT, Krasnykh V, Curiel DT, Blackwell JL. Substitution of the adenovirus serotype 5 knob with a serotype 3 knob enhances multiple steps in virus replication. Cancer Research. 63: 1262-9. PMID 12649186  0.363
2003 Rots MG, Curiel DT, Gerritsen WR, Haisma HJ. Targeted cancer gene therapy: the flexibility of adenoviral gene therapy vectors. Journal of Controlled Release : Official Journal of the Controlled Release Society. 87: 159-65. PMID 12618032 DOI: 10.1016/S0168-3659(02)00360-7  0.661
2003 Arafat WO, Buchsbaum DJ, Gómez-Navarro J, Tawil SA, Olsen C, Xiang J, El-Akad H, Salama AM, Badib AO, Stackhouse MA, Curiel DT. An adenovirus encoding proapoptotic Bax synergistically radiosensitizes malignant glioma. International Journal of Radiation Oncology, Biology, Physics. 55: 1037-50. PMID 12605984 DOI: 10.1016/S0360-3016(02)04488-7  0.577
2003 Hemminki A, Kanerva A, Kremer EJ, Bauerschmitz GJ, Smith BF, Liu B, Wang M, Desmond RA, Keriel A, Barnett B, Baker HJ, Siegal GP, Curiel DT. A canine conditionally replicating adenovirus for evaluating oncolytic virotherapy in a syngeneic animal model. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 163-73. PMID 12597904 DOI: 10.1016/S1525-0016(02)00049-7  0.412
2003 Hakkarainen T, Hemminki A, Pereboev AV, Barker SD, Asiedu CK, Strong TV, Kanerva A, Wahlfors J, Curiel DT. CD40 is expressed on ovarian cancer cells and can be utilized for targeting adenoviruses. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 619-24. PMID 12576427  0.717
2003 Uil TG, Seki T, Dmitriev I, Kashentseva E, Douglas JT, Rots MG, Middeldorp JM, Curiel DT. Generation of an adenoviral vector containing an addition of a heterologous ligand to the serotype 3 fiber knob. Cancer Gene Therapy. 10: 121-4. PMID 12536200 DOI: 10.1038/Sj.Cgt.7700543  0.399
2003 Yamamoto M, Davydova J, Takayama K, Alemany R, Curiel DT. Transcription initiation activity of adenovirus left-end sequence in adenovirus vectors with e1 deleted. Journal of Virology. 77: 1633-7. PMID 12502881 DOI: 10.1128/Jvi.77.2.1633-1637.2003  0.31
2003 Kanerva A, Wang M, Bauerschmitz GJ, Lam JT, Desmond RA, Bhoola SM, Barnes MN, Alvarez RD, Siegal GP, Curiel DT, Hemminki A. Gene transfer to ovarian cancer versus normal tissues with fiber-modified adenoviruses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 695-704. PMID 12027553 DOI: 10.1006/Mthe.2002.0599  0.498
2003 Arafat W, Buchsbaum D, Kaliberov S, Li F, Zhu Z, Curiel D. A novel radiation/tissue-specific promoter for gene therapy of brain tumors International Journal of Radiation Oncology*Biology*Physics. 57: S146. DOI: 10.1016/S0360-3016(03)00915-5  0.545
2003 Lee C, Park K, Yanagisawa K, Dikov MM, Nadaf S, Roberts JR, Curiel DT, Carbone DP. O-155 Combined gene therapy with conditionally replicating adenovirus and replication defective adenovirus improves the efficacy of gene therapy Lung Cancer. 41: S47. DOI: 10.1016/S0169-5002(03)91813-7  0.353
2003 Yamamoto M, Davydova J, Le LP, Ono HA, Ramirez PJ, Gavrikova T, Krasnykh V, Curiel DT. Infectivity enhanced, COX-2 promoter-based, conditionally replicative adenovirus for esophageal adenocarcinoma Gastroenterology. 124: A293. DOI: 10.1016/S0016-5085(03)81473-7  0.311
2002 Haviv YS, Takayama K, Glasgow JN, Blackwell JL, Wang M, Lei X, Curiel DT. A model system for the design of armed replicating adenoviruses using p53 as a candidate transgene. Molecular Cancer Therapeutics. 1: 321-8. PMID 12489848  0.379
2002 Barnes MN, Coolidge CJ, Hemminki A, Alvarez RD, Curiel DT. Conditionally replicative adenoviruses for ovarian cancer therapy. Molecular Cancer Therapeutics. 1: 435-9. PMID 12477056  0.347
2002 Wu H, Dmitriev I, Kashentseva E, Seki T, Wang M, Curiel DT. Construction and characterization of adenovirus serotype 5 packaged by serotype 3 hexon. Journal of Virology. 76: 12775-82. PMID 12438602 DOI: 10.1128/Jvi.76.24.12775-12782.2002  0.701
2002 Zhang HG, Xie J, Dmitriev I, Kashentseva E, Curiel DT, Hsu HC, Mountz JD. Addition of six-His-tagged peptide to the C terminus of adeno-associated virus VP3 does not affect viral tropism or production. Journal of Virology. 76: 12023-31. PMID 12414944 DOI: 10.1128/Jvi.76.23.12023-12031.2002  0.342
2002 Grill J, Lamfers ML, van Beusechem VW, Dirven CM, Pherai DS, Kater M, Van der Valk P, Vogels R, Vandertop WP, Pinedo HM, Curiel DT, Gerritsen WR. The organotypic multicellular spheroid is a relevant three-dimensional model to study adenovirus replication and penetration in human tumors in vitro. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 609-14. PMID 12409259 DOI: 10.1016/S1525-0016(02)90713-6  0.51
2002 Bilbao G, Contreras JL, Curiel DT. Genetically engineered intracellular single-chain antibodies in gene therapy. Molecular Biotechnology. 22: 191-211. PMID 12405266 DOI: 10.1385/Mb:22:2:191  0.37
2002 Clement A, Pereboev A, Curiel DT, Dong SS, Hutchings A, Thomas JM. Converting nonhuman primate dendritic cells into potent antigen-specific cellular immunosuppressants by genetic modification. Immunologic Research. 26: 297-302. PMID 12403367 DOI: 10.1385/Ir:26:1-3:297  0.339
2002 de Gruijl TD, Luykx-de Bakker SA, Tillman BW, van den Eertwegh AJ, Buter J, Lougheed SM, van der Bij GJ, Safer AM, Haisma HJ, Curiel DT, Scheper RJ, Pinedo HM, Gerritsen WR. Prolonged maturation and enhanced transduction of dendritic cells migrated from human skin explants after in situ delivery of CD40-targeted adenoviral vectors. Journal of Immunology (Baltimore, Md. : 1950). 169: 5322-31. PMID 12391253 DOI: 10.4049/Jimmunol.169.9.5322  0.797
2002 Lamfers ML, Grill J, Dirven CM, Van Beusechem VW, Geoerger B, Van Den Berg J, Alemany R, Fueyo J, Curiel DT, Vassal G, Pinedo HM, Vandertop WP, Gerritsen WR. Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy. Cancer Research. 62: 5736-42. PMID 12384532  0.529
2002 Asiedu C, Dong SS, Pereboev A, Wang W, Navarro J, Curiel DT, Thomas JM. Rhesus monocyte-derived dendritic cells modified to over-express TGF-beta1 exhibit potent veto activity. Transplantation. 74: 629-637. PMID 12352878 DOI: 10.1097/00007890-200209150-00008  0.357
2002 Barnett BG, Tillman BW, Curiel DT, Douglas JT. Dual targeting of adenoviral vectors at the levels of transduction and transcription enhances the specificity of gene expression in cancer cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 377-85. PMID 12231174 DOI: 10.1006/Mthe.2002.0670  0.77
2002 Wu H, Seki T, Dmitriev I, Uil T, Kashentseva E, Han T, Curiel DT. Double modification of adenovirus fiber with RGD and polylysine motifs improves coxsackievirus-adenovirus receptor-independent gene transfer efficiency. Human Gene Therapy. 13: 1647-53. PMID 12228019 DOI: 10.1089/10430340260201734  0.719
2002 Witlox MA, Van Beusechem VW, Grill J, Haisma HJ, Schaap G, Bras J, Van Diest P, De Gast A, Curiel DT, Pinedo HM, Gerritsen WR, Wuisman PI. Epidermal growth factor receptor targeting enhances adenoviral vector based suicide gene therapy of osteosarcoma. The Journal of Gene Medicine. 4: 510-6. PMID 12221644 DOI: 10.1002/Jgm.308  0.677
2002 Hemminki A, Wang M, Desmond RA, Strong TV, Alvarez RD, Curiel DT. Serum and ascites neutralizing antibodies in ovarian cancer patients treated with intraperitoneal adenoviral gene therapy. Human Gene Therapy. 13: 1505-14. PMID 12215271 DOI: 10.1089/10430340260185139  0.362
2002 Kim M, Zinn KR, Barnett BG, Sumerel LA, Krasnykh V, Curiel DT, Douglas JT. The therapeutic efficacy of adenoviral vectors for cancer gene therapy is limited by a low level of primary adenovirus receptors on tumour cells. European Journal of Cancer (Oxford, England : 1990). 38: 1917-26. PMID 12204675 DOI: 10.1016/S0959-8049(02)00131-4  0.494
2002 Dirven CM, Grill J, Lamfers ML, Van der Valk P, Leonhart AM, Van Beusechem VW, Haisma HJ, Pinedo HM, Curiel DT, Vandertop WP, Gerritsen WR. Gene therapy for meningioma: improved gene delivery with targeted adenoviruses. Journal of Neurosurgery. 97: 441-9. PMID 12186474 DOI: 10.3171/Jns.2002.97.2.0441  0.662
2002 Nettelbeck DM, Rivera AA, Balagué C, Alemany R, Curiel DT. Novel oncolytic adenoviruses targeted to melanoma: specific viral replication and cytolysis by expression of E1A mutants from the tyrosinase enhancer/promoter. Cancer Research. 62: 4663-70. PMID 12183423  0.337
2002 Pereboev AV, Asiedu CK, Kawakami Y, Dong SS, Blackwell JL, Kashentseva EA, Triozzi PL, Aldrich WA, Curiel DT, Thomas JM, Dmitriev IP. Coxsackievirus-adenovirus receptor genetically fused to anti-human CD40 scFv enhances adenoviral transduction of dendritic cells. Gene Therapy. 9: 1189-93. PMID 12170383 DOI: 10.1038/Sj.Gt.3301767  0.44
2002 Belousova N, Krendelchtchikova V, Curiel DT, Krasnykh V. Modulation of adenovirus vector tropism via incorporation of polypeptide ligands into the fiber protein. Journal of Virology. 76: 8621-31. PMID 12163581 DOI: 10.1128/Jvi.76.17.8621-8631.2002  0.405
2002 Kaliberov SA, Buchsbaum DJ, Gillespie GY, Curiel DT, Arafat WO, Carpenter M, Stackhouse MA. Adenovirus-mediated transfer of BAX driven by the vascular endothelial growth factor promoter induces apoptosis in lung cancer cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 190-8. PMID 12161185 DOI: 10.1006/Mthe.2002.0648  0.692
2002 Haviv YS, Blackwell JL, Kanerva A, Nagi P, Krasnykh V, Dmitriev I, Wang M, Naito S, Lei X, Hemminki A, Carey D, Curiel DT. Adenoviral gene therapy for renal cancer requires retargeting to alternative cellular receptors. Cancer Research. 62: 4273-81. PMID 12154029  0.368
2002 Seki T, Dmitriev I, Suzuki K, Kashentseva E, Takayama K, Rots M, Uil T, Wu H, Wang M, Curiel DT. Fiber shaft extension in combination with HI loop ligands augments infectivity for CAR-negative tumor targets but does not enchance hepatotropism in vivo Gene Therapy. 9: 1101-1108. PMID 12140738 DOI: 10.1038/Sj.Gt.3301815  0.72
2002 Bilbao G, Contreras JL, Dmitriev I, Smyth CA, Jenkins S, Eckhoff D, Thomas F, Thomas J, Curiel DT. Genetically modified adenovirus vector containing an RGD peptide in the HI loop of the fiber knob improves gene transfer to nonhuman primate isolated pancreatic islets. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2: 237-43. PMID 12096786 DOI: 10.1034/J.1600-6143.2002.20308.X  0.449
2002 Dmitriev IP, Kashentseva EA, Curiel DT. Engineering of adenovirus vectors containing heterologous peptide sequences in the C terminus of capsid protein IX. Journal of Virology. 76: 6893-9. PMID 12072490 DOI: 10.1128/Jvi.76.14.6893-6899.2002  0.433
2002 Hemminki A, Zinn KR, Liu B, Chaudhuri TR, Desmond RA, Rogers BE, Barnes MN, Alvarez RD, Curiel DT. In vivo molecular chemotherapy and noninvasive imaging with an infectivity-enhanced adenovirus. Journal of the National Cancer Institute. 94: 741-9. PMID 12011224 DOI: 10.1093/Jnci/94.10.741  0.433
2002 Zinn KR, Chaudhuri TR, Krasnykh VN, Buchsbaum DJ, Belousova N, Grizzle WE, Curiel DT, Rogers BE. Gamma camera dual imaging with a somatostatin receptor and thymidine kinase after gene transfer with a bicistronic adenovirus in mice. Radiology. 223: 417-25. PMID 11997547 DOI: 10.1148/Radiol.2232010501  0.588
2002 Zhang HG, Xie J, Xu L, Yang P, Xu X, Sun S, Wang Y, Curiel DT, Hsu HC, Mountz JD. Hepatic DR5 induces apoptosis and limits adenovirus gene therapy product expression in the liver. Journal of Virology. 76: 5692-700. PMID 11991997 DOI: 10.1128/Jvi.76.11.5692-5700.2002  0.405
2002 McKay T, Reynolds P, Jezzard S, Curiel D, Coutelle C. Secretin-Mediated Gene Delivery, a Specific Targeting Mechanism with Potential for Treatment of Biliary and Pancreatic Disease in Cystic Fibrosis Molecular Therapy. 5: 447-454. PMID 11945072 DOI: 10.1006/Mthe.2002.0560  0.432
2002 Adachi Y, Matsubara S, Muramatsu T, Curiel DT, Reynolds PN. Midkine promoter-based adenoviral suicide gene therapy to midkine-positive pediatric tumor. Journal of Pediatric Surgery. 37: 588-92. PMID 11912516 DOI: 10.1053/Jpsu.2002.31615  0.472
2002 Gómez-Navarro J, Curiel DT. Conditionally replicative adenoviral vectors for cancer gene therapy. The Lancet. Oncology. 1: 148-58. PMID 11905653 DOI: 10.1016/S1470-2045(00)00030-9  0.443
2002 Arafat WO, Gómez-Navarro J, Buchsbaum DJ, Xiang J, Wang M, Casado E, Barker SD, Mahasreshti PJ, Haisma HJ, Barnes MN, Siegal GP, Alvarez RD, Hemminki A, Nettelbeck DM, Curiel DT. Effective single chain antibody (scFv) concentrations in vivo via adenoviral vector mediated expression of secretory scFv. Gene Therapy. 9: 256-62. PMID 11896464 DOI: 10.1038/Sj.Gt.3301639  0.818
2002 Bauerschmitz GJ, Lam JT, Kanerva A, Suzuki K, Nettelbeck DM, Dmitriev I, Krasnykh V, Mikheeva GV, Barnes MN, Alvarez RD, Dall P, Alemany R, Curiel DT, Hemminki A. Treatment of ovarian cancer with a tropism modified oncolytic adenovirus. Cancer Research. 62: 1266-70. PMID 11888888  0.348
2002 Kruyt FA, Curiel DT. Toward a new generation of conditionally replicating adenoviruses: pairing tumor selectivity with maximal oncolysis. Human Gene Therapy. 13: 485-95. PMID 11874627 DOI: 10.1089/10430340252809784  0.416
2002 Contreras JL, Bilbao G, Smyth CA, Eckhoff DE, Jiang XL, Jenkins S, Thomas FT, Curiel DT, Thomas JM. Cytoprotection of pancreatic islets before and early after transplantation using gene therapy. Kidney International. 61: S79-84. PMID 11841618 DOI: 10.1046/J.1523-1755.2002.0610S1079.X  0.31
2002 Curiel TJ, Curiel DT. Tumor immunotherapy: inching toward the finish line. The Journal of Clinical Investigation. 109: 311-2. PMID 11827989 DOI: 10.1172/Jci15042  0.395
2002 Kashentseva EA, Seki T, Curiel DT, Dmitriev IP. Adenovirus targeting to c-erbB-2 oncoprotein by single-chain antibody fused to trimeric form of adenovirus receptor ectodomain. Cancer Research. 62: 609-16. PMID 11809717  0.396
2002 Kanerva A, Mikheeva GV, Krasnykh V, Coolidge CJ, Lam JT, Mahasreshti PJ, Barker SD, Straughn M, Barnes MN, Alvarez RD, Hemminki A, Curiel DT. Targeting adenovirus to the serotype 3 receptor increases gene transfer efficiency to ovarian cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 275-80. PMID 11801569  0.767
2002 Holm PS, Bergmann S, Jürchott K, Lage H, Brand K, Ladhoff A, Mantwill K, Curiel DT, Dobbelstein M, Dietel M, Gänsbacher B, Royer HD. YB-1 relocates to the nucleus in adenovirus-infected cells and facilitates viral replication by inducing E2 gene expression through the E2 late promoter Journal of Biological Chemistry. 277: 10427-10434. PMID 11788582 DOI: 10.1074/Jbc.M106955200  0.388
2002 Wesseling JG, Yamamoto M, Adachi Y, Bosma PJ, van Wijland M, Blackwell JL, Li H, Reynolds PN, Dmitriev I, Vickers SM, Huibregtse K, Curiel DT. Midkine and cyclooxygenase-2 promoters are promising for adenoviral vector gene delivery of pancreatic carcinoma. Cancer Gene Therapy. 8: 990-6. PMID 11781662 DOI: 10.1038/Sj.Cgt.7700403  0.456
2002 Seki T, Dmitriev I, Kashentseva E, Takayama K, Rots M, Suzuki K, Curiel DT. Artificial extension of the adenovirus fiber shaft inhibits infectivity in coxsackievirus and adenovirus receptor-positive cell lines. Journal of Virology. 76: 1100-8. PMID 11773386 DOI: 10.1128/Jvi.76.3.1100-1108.2002  0.416
2002 Zou W, Borvak J, Wei S, Isaeva T, Curiel DT, Curiel TJ. Reciprocal regulation of plasmacytoid dendritic cells and monocytes during viral infection. European Journal of Immunology. 31: 3833-9. PMID 11745405 DOI: 10.1002/1521-4141(200112)31:12<3833::Aid-Immu3833>3.0.Co;2-Y  0.313
2002 Haviv YS, Curiel DT. Conditional gene targeting for cancer gene therapy. Advanced Drug Delivery Reviews. 53: 135-54. PMID 11731024 DOI: 10.1016/S0169-409X(01)00225-3  0.477
2002 Buchsbaum DJ, Curiel DT. Gene therapy for the treatment of cancer. Cancer Biotherapy & Radiopharmaceuticals. 16: 275-88. PMID 11602998 DOI: 10.1089/108497801753131354  0.562
2002 Van der Poel H, Molena B, Haisma H, Rodriguez R, Curiel D, Gerritsen W. EGF-receptor targeting of replication competent adenovirus enhances cytotoxicity in bladder cancer European Urology Supplements. 1: 43. DOI: 10.1016/S1569-9056(02)80161-0  0.619
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