William E. Grizzle - Publications

Affiliations: 
Cell Biology University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Immunology

319 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Thomas A, Samykutty A, Gomez-Gutierrez JG, Yin W, Egger ME, McNally M, Chuong P, MacCuaig WM, Albeituni S, Zeiderman M, Li M, Edil BH, Grizzle WE, McMasters KM, McNally LR. Actively Targeted Nanodelivery of Echinomycin Induces Autophagy-Mediated Death in Chemoresistant Pancreatic Cancer In Vivo. Cancers. 12. PMID 32823919 DOI: 10.3390/Cancers12082279  0.358
2020 Davis M, Martini R, Newman L, Elemento O, White J, Verma A, Datta I, Adrianto I, Chen Y, Gardner K, Kim HG, Colomb WD, Eltoum IE, Frost AR, Grizzle WE, et al. Identification of Distinct Heterogenic Subtypes and Molecular Signatures Associated with African Ancestry in Triple Negative Breast Cancer Using Quantified Genetic Ancestry Models in Admixed Race Populations. Cancers. 12. PMID 32414099 DOI: 10.3390/Cancers12051220  0.328
2020 Chandrashekar DS, Chakravarthi BVSK, Robinson AD, Anderson JC, Agarwal S, Balasubramanya SAH, Eich ML, Bajpai AK, Davuluri S, Guru MS, Guru AS, Naik G, Della Manna DL, Acharya KK, Carskadon S, ... ... Grizzle WE, et al. Therapeutically actionable PAK4 is amplified, overexpressed, and involved in bladder cancer progression. Oncogene. PMID 32231273 DOI: 10.1038/S41388-020-1275-7  0.378
2020 Vaklavas C, Roberts BS, Varley KE, Lin NU, Liu MC, Rugo HS, Puhalla S, Nanda R, Storniolo AM, Carey LA, Saleh MN, Li Y, Delossantos JF, Grizzle WE, LoBuglio AF, et al. TBCRC 002: a phase II, randomized, open-label trial of preoperative letrozole with or without bevacizumab in postmenopausal women with newly diagnosed stage 2/3 hormone receptor-positive and HER2-negative breast cancer. Breast Cancer Research : Bcr. 22: 22. PMID 32070401 DOI: 10.1186/S13058-020-01258-X  0.321
2020 Vaklavas C, Blume SW, Grizzle WE. Hallmarks and Determinants of Oncogenic Translation Revealed by Ribosome Profiling in Models of Breast Cancer. Translational Oncology. 13: 452-470. PMID 31911279 DOI: 10.1016/J.Tranon.2019.12.002  0.33
2020 Dean-Colomb WM, Ahmed S, Karanam B, Wang H, Davis M, Grizzle WE, Gardner K, Yates C. Effect of Kaiso on immune signaling of breast cancer exosomes. Journal of Clinical Oncology. 38: 3088-3088. DOI: 10.1200/Jco.2020.38.15_Suppl.3088  0.376
2019 Grizzle WE, Kittles RA, Rais-Bahrami S, Shah E, Adams GW, DeGuenther MS, Kolettis PN, Nix JW, Bryant JE, Chinsky R, Kearns JE, Dehimer K, Terrin N, Chang H, Gaston SM. Self-Identified African Americans and prostate cancer risk: West African genetic ancestry is associated with prostate cancer diagnosis and with higher Gleason sum on biopsy. Cancer Medicine. PMID 31568648 DOI: 10.1002/Cam4.2434  0.308
2019 Behring M, Hale K, Ozaydin B, Grizzle WE, Sodeke SO, Manne U. Inclusiveness and ethical considerations for observational, translational, and clinical cancer health disparity research. Cancer. PMID 31502259 DOI: 10.1002/Cncr.32495  0.306
2019 Demark-Wahnefried W, Rogers LQ, Gibson JT, Harada S, Frugé AD, Oster RA, Grizzle WE, Norian LA, Yang ES, Della Manna D, Jones LW, Azrad M, Krontiras H. Randomized Trial of Weight Loss in Primary Breast Cancer: Impact on Body Composition, Circulating Biomarkers and Tumor Characteristics. International Journal of Cancer. PMID 31442303 DOI: 10.1002/Ijc.32637  0.354
2019 Al Diffalha S, Sexton KC, Watson PH, Grizzle WE. The Importance of Human Tissue Bioresources in Advancing Biomedical Research. Biopreservation and Biobanking. 17: 209-212. PMID 31188626 DOI: 10.1089/Bio.2019.0039  0.32
2019 Lin H, Wang H, White J, Karanam B, Ghebremedhin A, Addai BA, Grizzle WE, Yates C. Abstract 5219: Kaiso as a novel therapeutic target in castration-resistant prostate cancer (CRPC) Cancer Research. 79: 5219-5219. DOI: 10.1158/1538-7445.Sabcs18-5219  0.384
2019 Samykutty A, McNally M, Thomas A, Grizzle W, McNally LR. Abstract 1952: Tumor microenvironment targeted Rosella nanoparticle for the detection of triple negative breast cancer by multispectral optoacoustic tomography Cancer Research. 79: 1952-1952. DOI: 10.1158/1538-7445.Sabcs18-1952  0.347
2019 Ahmed SU, Jenkins B, Adu-Addai B, Karanam B, Davis MB, Grizzle WE, Wang H, Yates CC. Abstract 1525: Kaiso influences immune signaling of breast cancer exosomes Cancer Research. 79: 1525-1525. DOI: 10.1158/1538-7445.Am2019-1525  0.38
2018 Gaston SM, Grizzle WE, Rais-Bahrami S, Kearney GP. Nitrocellulose tissue prints: an innovative approach to preparing high quality DNA and RNA from prostate biopsies without compromising the cores for pathology diagnosis Translational Andrology and Urology. 7. PMID 30363516 DOI: 10.21037/Tau.2018.09.01  0.34
2018 Chakravarthi BVSK, Rodriguez Pena MDC, Agarwal S, Chandrashekar DS, Hodigere Balasubramanya SA, Jabboure FJ, Matoso A, Bivalacqua TJ, Rezaei K, Chaux A, Grizzle WE, Sonpavde G, Gordetsky J, Netto GJ, Varambally S. A Role for De Novo Purine Metabolic Enzyme PAICS in Bladder Cancer Progression. Neoplasia (New York, N.Y.). 20: 894-904. PMID 30121007 DOI: 10.1016/J.Neo.2018.07.006  0.393
2018 Davis M, Tripathi S, Hughley R, He Q, Bae S, Karanam B, Martini R, Newman L, Colomb W, Grizzle W, Yates C. AR negative triple negative or "quadruple negative" breast cancers in African American women have an enriched basal and immune signature. Plos One. 13: e0196909. PMID 29912871 DOI: 10.1371/Journal.Pone.0196909  0.359
2018 Vaklavas C, Zinn KR, Samuel SL, Meng Z, Grizzle WE, Choi H, Blume SW. Translational control of the undifferentiated phenotype in ER‑positive breast tumor cells: Cytoplasmic localization of ERα and impact of IRES inhibition. Oncology Reports. PMID 29620220 DOI: 10.3892/Or.2018.6332  0.341
2018 Samykutty A, McNally MW, Grizzle WE, Chiba A, Thomas A, McNally LR. Abstract 4122: Acidic tumor microenvironment targeted wormhole-shaped mesoporous silica nanoparticles to detect ovarian cancer by multispectral optoacoustic tomography Cancer Research. 78: 4122-4122. DOI: 10.1158/1538-7445.Am2018-4122  0.345
2018 Hayes JT, Samykutty A, McNally M, Thomas A, Chiba A, Grizzle W, Winkfield KM, McNally LR. Abstract 3727: Dual acidic pH targeted mesoporous silica nanoparticles for noninvasive detection of triple negative breast cancer Cancer Research. 78: 3727-3727. DOI: 10.1158/1538-7445.Am2018-3727  0.313
2018 Gaston SM, Rais-Bahrami S, Kearns J, Otali D, Oelschlager D, DeGuenther MS, Nix JW, Kolettis PN, Bryant JE, Oster RA, Grizzle WE. Abstract 372: Obesity matters: Prostate cancers that overexpress fatty acid binding protein 5 are more common in men who are overweight or obese Cancer Research. 78: 372-372. DOI: 10.1158/1538-7445.Am2018-372  0.347
2018 Gaston S, Rais-Bahrami S, Nix J, Kolettis P, Bryant J, Kearns J, Denise O, Otali D, Grizzle W. Mp29-15 Make It From Scratch Or Have It Delivered? Satisfying The Fatty Acid Demand Of Prostate Cancer The Journal of Urology. 199. DOI: 10.1016/J.Juro.2018.02.935  0.302
2017 Zhu B, Lindsey A, Li N, Lee K, Ramirez-Alcantara V, Canzoneri JC, Fajardo A, Madeira da Silva L, Thomas M, Piazza JT, Yet L, Eberhardt BT, Gurpinar E, Otali D, Grizzle W, et al. Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling. Oncotarget. 8: 69264-69280. PMID 29050202 DOI: 10.18632/Oncotarget.20566  0.34
2017 Demark-Wahnefried W, Rais-Bahrami S, Desmond RA, Gordetsky JB, Hunter GR, Yang ES, Azrad M, Frugé AD, Tsuruta Y, Norian LA, Segal R, Grizzle WE. Presurgical weight loss affects tumour traits and circulating biomarkers in men with prostate cancer. British Journal of Cancer. PMID 28881355 DOI: 10.1038/Bjc.2017.303  0.302
2017 Vaklavas C, Blume SW, Grizzle WE. Translational Dysregulation in Cancer: Molecular Insights and Potential Clinical Applications in Biomarker Development. Frontiers in Oncology. 7: 158. PMID 28798901 DOI: 10.3389/Fonc.2017.00158  0.357
2017 Van Neste L, Groskopf J, Grizzle WE, Adams GW, DeGuenther MS, Kolettis PN, Bryant JE, Kearney GP, Kearney MC, Van Criekinge W, Gaston SM. Epigenetic risk score improves prostate cancer risk assessment. The Prostate. PMID 28762545 DOI: 10.1002/Pros.23385  0.319
2017 Gaston SM, Kearns J, Adams GW, Rais-Bahrami S, Nix J, Kolettis PN, Bryant JE, Otali D, Grizzle WE. Satisfying the fatty acid demand of prostate cancer: De novo synthesis versus uptake as alternative and potentially cooperative prostate cancer phenotypes. Journal of Clinical Oncology. 35: 107-107. DOI: 10.1200/Jco.2017.35.6_Suppl.107  0.368
2017 Grizzle WE. Abstract IA24: Reduced Availability for Research of Human Tissues from Minority Populations Cancer Epidemiology, Biomarkers & Prevention. 26. DOI: 10.1158/1538-7755.Disp16-Ia24  0.372
2017 Gaston SM, Otali D, Kearns J, Dehimer K, Adams GW, Rais-Bahrami S, Nix J, Bryant JE, Kolettis P, Grizzle WE. Abstract C40: A biopsy-focused approach to molecular studies of prostate cancer in African Americans: the Birmingham Alabama Prostate Cancer Consortium (BAPrCa) Cancer Epidemiology, Biomarkers & Prevention. 26. DOI: 10.1158/1538-7755.Disp16-C40  0.354
2017 Lindsey AS, Lee K, Andrews J, Chang WL, Ramirez-Alcantara V, Tan M, Grizzle W, Clapper ML, Piazza G. Abstract B21: PDE10A overexpression in colon cancer cells and tumors relative to normal colonocytes and colon mucosa Cancer Research. 77. DOI: 10.1158/1538-7445.Crc16-B21  0.411
2017 Ahmed SU, Triphati S, Grizzle WE, Wang H, Yates CC. Abstract 5414: Kaiso influences the exosome profile required to induce cell proliferation, migration and metabolism in breast cancer Cancer Research. 77: 5414-5414. DOI: 10.1158/1538-7445.Am2017-5414  0.384
2017 Gaston SM, Kearns J, Adams GW, Rais-Bahrami S, Nix JW, Kolettis PN, Bryant JE, DeGuenther MS, Oelschlager D, Otali D, Grizzle WE. Abstract 457: Satisfying the fatty acid demand of prostate cancer: Outlier overexpression of genes involved inde novosynthesis vs fatty acid uptake define two different and potentially synergistic prostate cancer phenotypes Cancer Research. 77: 457-457. DOI: 10.1158/1538-7445.Am2017-457  0.316
2017 Otali DA, Oelschlager DK, Kearns J, Gaston SM, Grizzle WE. Abstract 2209: Characterization of FABP5 antibodies in prostate Cancer Research. 77: 2209-2209. DOI: 10.1158/1538-7445.Am2017-2209  0.354
2017 Ramirez-Alcantara V, Zhu B, Chen X, Savai R, Subbarayal P, Schuler MA, Lee KJ, Lindsey AS, Berry KL, Otali D, Canzoneri J, Valiyaveettil J, Keeton A, Coward L, Gorman G, ... Grizzle W, et al. Abstract 1140: Characterization of a novel PDE10 inhibitor in lung tumor cells and an orthotopic mouse model of lung cancer Cancer Research. 77: 1140-1140. DOI: 10.1158/1538-7445.Am2017-1140  0.365
2016 McDaniel JM, Varley KE, Gertz J, Savic DS, Roberts BS, Bailey SK, Shevde LA, Ramaker RC, Lasseigne BN, Kirby MK, Newberry KM, Partridge EC, Jones AL, Boone B, Levy SE, ... ... Grizzle WE, et al. Genomic regulation of invasion by STAT3 in triple negative breast cancer. Oncotarget. PMID 28030809 DOI: 10.18632/Oncotarget.14153  0.378
2016 Tsuruta Y, Rogers LQ, Krontiras H, Grizzle WE, Frugé AD, Oster RA, Umphrey HR, Jones LW, Azrad M, Demark-Wahnefried W. Exploring effects of presurgical weight loss among women with stage 0-II breast cancer: protocol for a randomised controlled feasibility trial. Bmj Open. 6: e012320. PMID 27633639 DOI: 10.1136/Bmjopen-2016-012320  0.308
2016 Vaklavas C, Grizzle WE, Choi H, Meng Z, Zinn KR, Shrestha K, Blume SW. IRES inhibition induces terminal differentiation and synchronized death in triple-negative breast cancer and glioblastoma cells. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. PMID 27460074 DOI: 10.1007/S13277-016-5161-4  0.352
2016 Kirby MK, Ramaker RC, Gertz J, Davis NS, Johnston BE, Oliver PG, Sexton KC, Greeno EW, Christein JD, Heslin MJ, Posey JA, Grizzle WE, Vickers SM, Buchsbaum DJ, Cooper SJ, et al. RNA sequencing of pancreatic adenocarcinoma tumors yields novel expression patterns associated with long-term survival and reveals a role for ANGPTL4. Molecular Oncology. PMID 27282075 DOI: 10.1016/J.Molonc.2016.05.004  0.316
2016 Zhang J, Riby JE, Conde L, Grizzle WE, Cui X, Skibola CF. A Fucus vesiculosus extract inhibits estrogen receptor activation and induces cell death in female cancer cell lines. Bmc Complementary and Alternative Medicine. 16: 151. PMID 27234961 DOI: 10.1186/S12906-016-1129-6  0.317
2016 Schultz MJ, Holdbrooks AT, Chakraborty A, Grizzle WE, Landen CN, Buchsbaum DJ, Conner MB, Arend RC, Yoon KJ, Klug C, Bullard DC, Kesterson RA, Oliver PG, O'Connor AK, Yoder BK, et al. The tumor-associated glycosyltransferase ST6Gal-I regulates stem cell transcription factors and confers a cancer stem cell phenotype. Cancer Research. PMID 27216178 DOI: 10.1158/0008-5472.Can-15-2834  0.4
2016 McNally LR, Mezera M, Morgan DE, Frederick PJ, Yang ES, Eltoum IE, Grizzle WE. Current and Emerging Clinical Applications of Multispectral Optoacoustic Tomography (MSOT) in Oncology. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27208064 DOI: 10.1158/1078-0432.Ccr-16-0573  0.32
2016 Otali D, Fredenburgh J, Oelschlager DK, Grizzle WE. A standard tissue as a control for histochemical and immunohistochemical staining. Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission. 1-18. PMID 27149658 DOI: 10.1080/10520295.2016.1179342  0.319
2016 Forero A, Li Y, Chen D, Grizzle WE, Updike KL, Merz ND, Downs-Kelly E, Burwell TC, Vaklavas C, Buchsbaum DJ, Myers RM, LoBuglio AF, Varley KE. Expression of the MHC Class II Pathway in Triple-Negative Breast Cancer Tumor Cells is Associated with a Good Prognosis and Infiltrating Lymphocytes. Cancer Immunology Research. PMID 26980599 DOI: 10.1158/2326-6066.Cir-15-0243  0.366
2016 Demark-Wahnefried W, Nix JW, Hunter GR, Rais-Bahrami S, Desmond RA, Chacko B, Morrow CD, Azrad M, Frugé AD, Tsuruta Y, Ptacek T, Tully SA, Segal R, Grizzle WE. Feasibility outcomes of a presurgical randomized controlled trial exploring the impact of caloric restriction and increased physical activity versus a wait-list control on tumor characteristics and circulating biomarkers in men electing prostatectomy for prostate cancer. Bmc Cancer. 16: 61. PMID 26850040 DOI: 10.1186/S12885-016-2075-X  0.356
2016 Kim H, Samuel SL, Lopez-Casas PP, Grizzle WE, Hidalgo M, Kovar J, Oelschlager DK, Zinn KR, Warram JM, Buchsbaum DJ. SPARC independent delivery of nab-paclitaxel without depleting tumor stroma in patient-derived pancreatic cancer xenografts. Molecular Cancer Therapeutics. PMID 26832793 DOI: 10.1158/1535-7163.Mct-15-0764  0.345
2016 Neste LV, Stewart G, Gaston SM, Grizzle WE, Adams GW, Kearney GP, Epstein JI, Harrison DJ, Partin AW, Criekinge WV. Combined DNA-methylation intensity and clinical risk score to stratify patients for high-grade disease. Journal of Clinical Oncology. 34: 51-51. DOI: 10.1200/Jco.2016.34.2_Suppl.51  0.31
2016 Naik G, Chen D, Crowley M, Crossman D, Sexton KC, Grizzle WE, Mehta AN, Sonpavde G. Whole-exome sequencing (WES) of penile squamous cell carcinoma (PSCC) to identify multiple recurrent mutations. Journal of Clinical Oncology. 34: 484-484. DOI: 10.1200/Jco.2016.34.2_Suppl.484  0.32
2016 Gaston SM, Rais-Bahrami S, Kittles R, Dehimer K, Otali D, Nix JW, Kolettis PN, Adams G, Grizzle WE. Abstract C72: Improving the accuracy and diagnostic power of prostate biopsy for African American patients: The Birmingham Alabama Prostate Cancer (BAPrCa) Consortium Cancer Epidemiology, Biomarkers & Prevention. 25. DOI: 10.1158/1538-7755.Disp15-C72  0.351
2016 Lindsey AS, Lee K, Zhu B, Arora R, Otali D, Ramirez-Alacantara V, Grizzle W, Piazza G. Abstract 4736: PDE10A overexpression in cancer cells and tumors as compared to normal cells and tissues Cancer Research. 76: 4736-4736. DOI: 10.1158/1538-7445.Am2016-4736  0.395
2016 Chuong P, Zeiderman M, Grizzle WE, McNally LR. Abstract 4238: Multispectral optoacoustic tomography detects orthotopic pancreatic tumorsin vivousing a nano-contrast agent Cancer Research. 76: 4238-4238. DOI: 10.1158/1538-7445.Am2016-4238  0.334
2016 Schultz MJ, Holdbrooks AT, Chakraborty A, Grizzle WE, Landen CN, Buchsbaum DJ, Conner MG, Arend RC, Yoon KJ, Klug CA, Bullard DC, Kesterson RA, Oliver PG, O’Connor AK, Yoder BK, et al. Abstract 3327: The tumor associated sialyltransferase ST6Gal-I promotes a cancer stem cell phenotype and upregulates stem-related transcription factors Cancer Research. 76: 3327-3327. DOI: 10.1158/1538-7445.Am2016-3327  0.395
2016 Vaklavas C, Grizzle WE, Choi H, Meng Z, Zinn KR, Blume SW. Abstract 3037: Tumor cell death triggered by sustained IRES inhibition is a population-wide event involving a quorum-sensing mechanism in which putative tumor stem cells are eliminated along with their progeny Cancer Research. 76: 3037-3037. DOI: 10.1158/1538-7445.Am2016-3037  0.373
2016 Gaston SM, Dehimer K, Kearns J, Chinsky K, Otali D, Oelschlager D, Rais-Bahrami S, Nix JW, Kolettis P, Adams GW, Grizzle WE. Abstract 20: Outlier overexpression of genes involved in fatty acid metabolism and processing define two aggressive prostate cancer phenotypes Cancer Research. 76: 20-20. DOI: 10.1158/1538-7445.Am2016-20  0.36
2015 Boone JD, Arend RC, Johnston BE, Cooper SJ, Gilchrist SA, Oelschlager DK, Grizzle WE, McGwin G, Gangrade A, Straughn JM, Buchsbaum DJ. Targeting the Wnt/β-catenin pathway in primary ovarian cancer with the porcupine inhibitor WNT974. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 26658453 DOI: 10.1038/Labinvest.2015.150  0.367
2015 Yin W, Kimbrough CW, Gomez-Gutierrez JG, Burns CT, Chuong P, Grizzle WE, McNally LR. Tumor specific liposomes improve detection of pancreatic adenocarcinoma in vivo using optoacoustic tomography. Journal of Nanobiotechnology. 13: 90. PMID 26627455 DOI: 10.1186/S12951-015-0139-8  0.302
2015 Ludwig MR, Kojima K, Bowersock GJ, Chen D, Jhala NC, Buchsbaum DJ, Grizzle WE, Klug CA, Mobley JA. Surveying the serologic proteome in a tissue specific kras(G12D) knockin mouse model of pancreatic cancer. Proteomics. PMID 26572242 DOI: 10.1002/Pmic.201500133  0.365
2015 Anderson JC, Willey CD, Mehta A, Welaya K, Chen D, Duarte CW, Ghatalia P, Arafat W, Madan A, Sudarshan S, Naik G, Grizzle WE, Choueiri TK, Sonpavde G. High Throughput Kinomic Profiling of Human Clear Cell Renal Cell Carcinoma Identifies Kinase Activity Dependent Molecular Subtypes. Plos One. 10: e0139267. PMID 26406598 DOI: 10.1371/Journal.Pone.0139267  0.331
2015 Li R, Zhang K, Penedo TL, Kragel CP, Grizzle WE, Hameed O, Siegal GP, Wei S. The RANK Pathway in Advanced Breast Cancer: Does Src Play a Role? Applied Immunohistochemistry & Molecular Morphology : Aimm / Official Publication of the Society For Applied Immunohistochemistry. PMID 26200837 DOI: 10.1097/Pai.0000000000000151  0.368
2015 Vaklavas C, Meng Z, Choi H, Grizzle WE, Zinn KR, Blume SW. Small molecule inhibitors of IRES-mediated translation. Cancer Biology & Therapy. 0. PMID 26177060 DOI: 10.1080/15384047.2015.1071729  0.346
2015 Putcha BD, Jia X, Katkoori VR, Salih C, Shanmugam C, Jadhav T, Bovell LC, Behring MP, Callens T, Messiaen L, Bae S, Grizzle WE, Singh KP, Manne U. Clinical Implications of Rabphillin-3A-Like Gene Alterations in Breast Cancer. Plos One. 10: e0129216. PMID 26070152 DOI: 10.1371/Journal.Pone.0129216  0.36
2015 Stanley J, Klepczyk L, Keene K, Wei S, Li Y, Forero A, Grizzle W, Wielgos M, Brazelton J, LoBuglio AF, Yang ES. PARP1 and phospho-p65 protein expression is increased in human HER2-positive breast cancers. Breast Cancer Research and Treatment. 150: 569-79. PMID 25833211 DOI: 10.1007/S10549-015-3359-6  0.346
2015 Forero-Torres A, Varley KE, Abramson VG, Li Y, Vaklavas C, Lin NU, Liu MC, Rugo HS, Nanda R, Storniolo AM, Traina TA, Patil S, Van Poznak CH, Nangia JR, Irvin WJ, ... ... Grizzle W, et al. TBCRC 019: A Phase II Trial of Nanoparticle Albumin-Bound Paclitaxel with or without the Anti-Death Receptor 5 Monoclonal Antibody Tigatuzumab in Patients with Triple-Negative Breast Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2722-9. PMID 25779953 DOI: 10.1158/1078-0432.Ccr-14-2780  0.348
2015 Che P, Yang Y, Han X, Hu M, Sellers JC, Londono-Joshi AI, Cai GQ, Buchsbaum DJ, Christein JD, Tang Q, Chen D, Li Q, Grizzle WE, Lu YY, Ding Q. S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase. Scientific Reports. 5: 8453. PMID 25677816 DOI: 10.1038/Srep08453  0.406
2015 Isayeva T, Xu J, Ragin C, Dai Q, Cooper T, Carroll W, Dayan D, Vered M, Wenig B, Rosenthal E, Grizzle W, Anderson J, Willey CD, Yang ES, Brandwein-Gensler M. The protective effect of p16(INK4a) in oral cavity carcinomas: p16(Ink4A) dampens tumor invasion-integrated analysis of expression and kinomics pathways. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 28: 631-53. PMID 25523612 DOI: 10.1038/Modpathol.2014.149  0.322
2015 Li N, Lee K, Xi Y, Zhu B, Gary BD, Ramírez-Alcántara V, Gurpinar E, Canzoneri JC, Fajardo A, Sigler S, Piazza JT, Chen X, Andrews J, Thomas M, Lu W, ... ... Grizzle WE, et al. Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity. Oncogene. 34: 1499-509. PMID 24704829 DOI: 10.1038/Onc.2014.94  0.363
2015 Gaston SM, Grizzle WE, Neste LV, Bigley J, Yen J, Adams GW, Kearney GP. Epigenetic field effects: Potential applications for detection of occult high-grade prostate cancer. Journal of Clinical Oncology. 33: 20-20. DOI: 10.1200/Jco.2015.33.7_Suppl.20  0.338
2015 Stanley JA, Klepczyk LC, Keene KS, Wei S, Li Y, Forero-Torres A, Grizzle WE, Wielgos M, Brazelton JD, LoBuglio AF, Yang ES. Expression levels of PARP1 and phospho-p65 protein in human HER2-positive breast cancers. Journal of Clinical Oncology. 33: 601-601. DOI: 10.1200/Jco.2015.33.15_Suppl.601  0.347
2015 Forero-Torres A, Varley KE, Li Y, Chen D, Grizzle WE, Downs-Kelly E, Burwell TC, Buchsbaum DJ, Myers RM, LoBuglio AF. MHC II antigen presentation pathway expression in triple-negative breast cancer. Journal of Clinical Oncology. 33: 1066-1066. DOI: 10.1200/Jco.2015.33.15_Suppl.1066  0.357
2015 Ramirez-Alcantara V, Schuler M, Zhu B, Li N, Gurpinar E, Otali D, Canzoneri J, Keeton A, Gary B, Russo S, Coward L, Gorman G, Grizzle W, Chen X, Boyd M, et al. Abstract 950: Antitumor activity of a novel phosphodiesterase 10 inhibitor in an orthotopic mouse model of lung cancer Cancer Research. 75: 950-950. DOI: 10.1158/1538-7445.Am2015-950  0.365
2015 Vaklavas C, Meng Z, Choi H, Grizzle WE, Zinn KR, Blume SW. Abstract 4363: Selective modulation of IRES-mediated translation in malignant cells Cancer Research. 75: 4363-4363. DOI: 10.1158/1538-7445.Am2015-4363  0.34
2015 Otali D, Maston VR, Oelschlager DK, Grizzle WE. Abstract 3380: Loss of immunorecognition of selected molecules during long-term storage of paraffin blocks Cancer Research. 75: 3380-3380. DOI: 10.1158/1538-7445.Am2015-3380  0.31
2015 Khanal A, Kimbrough CW, Garbett NC, Burlison JA, Grizzle WE, McNally LR. Abstract 1500: Syndecan-1 targeted mesoporous silica-coated gold nanorods act as theranostic agents forin vivodetection of orthotopic pancreatic tumors using multispectral optoacoustic tomography Cancer Research. 75: 1500-1500. DOI: 10.1158/1538-7445.Am2015-1500  0.338
2015 Neste LV, Criekinge WV, Bigley J, Grizzle WE, Adams GW, Kearney GP, Gaston SM. Mp6-12 Epigenetic Assay Stratifies Prostate Cancer Patients' Risk For Aggressiveness The Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.259  0.318
2014 Varley KE, Gertz J, Roberts BS, Davis NS, Bowling KM, Kirby MK, Nesmith AS, Oliver PG, Grizzle WE, Forero A, Buchsbaum DJ, LoBuglio AF, Myers RM. Recurrent read-through fusion transcripts in breast cancer. Breast Cancer Research and Treatment. 146: 287-97. PMID 24929677 DOI: 10.1007/S10549-014-3019-2  0.34
2014 Nolen BM, Brand RE, Prosser D, Velikokhatnaya L, Allen PJ, Zeh HJ, Grizzle WE, Huang Y, Lomakin A, Lokshin AE. Prediagnostic serum biomarkers as early detection tools for pancreatic cancer in a large prospective cohort study. Plos One. 9: e94928. PMID 24747429 DOI: 10.1371/Journal.Pone.0094928  0.311
2014 Bhardwaj A, Singh S, Srivastava SK, Arora S, Hyde SJ, Andrews J, Grizzle WE, Singh AP. Restoration of PPP2CA expression reverses epithelial-to-mesenchymal transition and suppresses prostate tumour growth and metastasis in an orthotopic mouse model. British Journal of Cancer. 110: 2000-10. PMID 24642616 DOI: 10.1038/Bjc.2014.141  0.307
2014 Chanda D, Lee JH, Sawant A, Hensel JA, Isayeva T, Reilly SD, Siegal GP, Smith C, Grizzle W, Singh R, Ponnazhagan S. Anterior gradient protein-2 is a regulator of cellular adhesion in prostate cancer. Plos One. 9: e89940. PMID 24587138 DOI: 10.1371/Journal.Pone.0089940  0.392
2014 Jones J, Wang H, Karanam B, Theodore S, Dean-Colomb W, Welch DR, Grizzle W, Yates C. Nuclear localization of Kaiso promotes the poorly differentiated phenotype and EMT in infiltrating ductal carcinomas. Clinical & Experimental Metastasis. 31: 497-510. PMID 24570268 DOI: 10.1007/S10585-014-9644-7  0.353
2014 Londoño-Joshi AI, Arend RC, Aristizabal L, Lu W, Samant RS, Metge BJ, Hidalgo B, Grizzle WE, Conner M, Forero-Torres A, Lobuglio AF, Li Y, Buchsbaum DJ. Effect of niclosamide on basal-like breast cancers. Molecular Cancer Therapeutics. 13: 800-11. PMID 24552774 DOI: 10.1158/1535-7163.Mct-13-0555  0.35
2014 Gurpinar E, Grizzle WE, Piazza GA. NSAIDs inhibit tumorigenesis, but how? Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 1104-13. PMID 24311630 DOI: 10.1158/1078-0432.Ccr-13-1573  0.344
2014 Zhang HG, Grizzle WE. Exosomes: a novel pathway of local and distant intercellular communication that facilitates the growth and metastasis of neoplastic lesions. The American Journal of Pathology. 184: 28-41. PMID 24269592 DOI: 10.1016/J.Ajpath.2013.09.027  0.332
2014 Benavides MA, Bosland MC, da Silva CP, Gomes Sares CT, de Oliveira AM, Kemp R, dos Reis RB, Martins VR, Sampaio SV, Bland KI, Grizzle WE, dos Santos JS. L-Methionine inhibits growth of human pancreatic cancer cells. Anti-Cancer Drugs. 25: 200-3. PMID 24126240 DOI: 10.1097/Cad.0000000000000038  0.341
2014 Devine DJ, Rostas JW, Metge BJ, Das S, Mulekar MS, Tucker JA, Grizzle WE, Buchsbaum DJ, Shevde LA, Samant RS. Loss of N-Myc interactor promotes epithelial-mesenchymal transition by activation of TGF-β/SMAD signaling. Oncogene. 33: 2620-8. PMID 23770854 DOI: 10.1038/Onc.2013.215  0.326
2014 Mehta AN, Willey CD, Anderson J, Welaya KY, Chen D, Ghatalia P, Madan A, Sudarshan S, Naik G, Grizzle WE, Choueiri TK, Sonpavde G. Comprehensive kinase profiling to classify clear cell (cc)-renal cell carcinoma (RCC). Journal of Clinical Oncology. 32: 409-409. DOI: 10.1200/Jco.2014.32.4_Suppl.409  0.314
2014 Mehta AN, Willey C, Crowley M, Anderson J, Chen D, Crossman D, Necchi A, Lorenzo Gd, Eigl BJ, Lee RJ, Harshman LC, Dorff TB, Galsky MD, Milowsky MI, Bolger G, ... ... Grizzle WE, et al. Integrated comprehensive high-throughput kinomics profiling and whole exome sequencing of penile squamous cell cancer (PSCC). Journal of Clinical Oncology. 32: 383-383. DOI: 10.1200/Jco.2014.32.4_Suppl.383  0.359
2014 Russo S, Li N, Lee K, Xi Y, Zhu B, Gary B, Ramirez V, Gurpinar E, Canzeroni J, Fajardo A, Sigler S, Piazza JT, Chen X, Andrews J, Li Y, ... ... Grizzle WE, et al. Phosphodiesterase 10, a novel target in colon cancer. Journal of Clinical Oncology. 32: 503-503. DOI: 10.1200/Jco.2014.32.3_Suppl.503  0.381
2014 Russo SM, Ramirez-Alcantara V, Schuler M, Zhu B, Li N, Canzoneri J, Keeton A, Grizzle WE, Chen X, Piazza G. PDE10 inhibitors suppress lung tumor growth in mice. Journal of Clinical Oncology. 32: e22187-e22187. DOI: 10.1200/Jco.2014.32.15_Suppl.E22187  0.331
2014 Jones J, Wang H, Karanam B, Theodore S, Dean-Colomb WM, Welch DR, Grizzle WE, Yates C. Nuclear localization of Kaiso as a prognostic biomarker and promotion of EMT in infiltrating ductal breast carcinomas. Journal of Clinical Oncology. 32: e22061-e22061. DOI: 10.1200/Jco.2014.32.15_Suppl.E22061  0.338
2014 Mehta AN, Willey CD, Anderson J, Welaya KY, Chen D, Ghatalia P, Madan A, Sudarshan S, Naik G, Grizzle WE, Choueiri TK, Sonpavde G. Comprehensive functional kinase profiling to classify clear cell (cc)-renal cell carcinoma (RCC). Journal of Clinical Oncology. 32: 4572-4572. DOI: 10.1200/Jco.2014.32.15_Suppl.4572  0.311
2014 Theodore SC, Wang H, Rhim J, Turner T, Davis M, Grizzle W, Yates CC. Abstract PL01-02: Functional biomarkers that promote African American prostate cancer through epigenetic regulation Cancer Epidemiology, Biomarkers & Prevention. 23. DOI: 10.1158/1538-7755.Disp13-Pl01-02  0.381
2014 Garcia DL, Sexton K, Grizzle WE, Betsou F. Abstract 5319: The role of ISBER (The International Society for Biological and Environmental Repositories) in cancer research Cancer Research. 74: 5319-5319. DOI: 10.1158/1538-7445.Am2014-5319  0.309
2014 Gaston SM, Kearney GP, Kittles R, Kolettis PN, Adams GW, Grizzle WE. Abstract 4710: Innovative technologies to overcome disparities in prostate cancer research: Using snap-frozen prostate biopsy tissue prints to expand patient representation in biorepository collections used for molecular biomarker research Cancer Research. 74: 4710-4710. DOI: 10.1158/1538-7445.Am2014-4710  0.35
2014 Hudson SV, Kimbrough C, Egger M, Khanal A, Smith ME, Grizzle WE, McNally LR. Abstract 4301: Detection and characterization of regions of hypoxia within orthotopic pancreatic tumors using multispectral optoacoustic tomography Cancer Research. 74: 4301-4301. DOI: 10.1158/1538-7445.Am2014-4301  0.35
2014 Gupta P, Ward AB, Mir H, Kaur G, Grizzle WE, Lillard JW, Singh S. Abstract 4047: Potential role of CXCR6-CXCL16 in prostate cancer progression and chemotherapeutic efficacy Cancer Research. 74: 4047-4047. DOI: 10.1158/1538-7445.Am2014-4047  0.405
2014 Mir H, Gupta P, Singh R, Sharma PK, Kaur G, Ward AB, Grizzle WE, Lillard JW, Singh S. Abstract 4003: Clinical and biological significance of CXCR6 in lung cancer Cancer Research. 74: 4003-4003. DOI: 10.1158/1538-7445.Am2014-4003  0.389
2014 Srivastava SK, Bhardwaj A, Arora S, Singh S, Grizzle WE, Singh AP. Abstract 3398: Reciprocal regulation ofMYBandCXCR4in pancreatic cancer cells: Potential pathobiological implications Cancer Research. 74: 3398-3398. DOI: 10.1158/1538-7445.Am2014-3398  0.405
2014 Nolen BM, Grizzle W, Brand R, Lokshin AE. Abstract 295: Urine and serum biomarkers of pancreatic cancer Cancer Research. 74: 295-295. DOI: 10.1158/1538-7445.Am2014-295  0.31
2014 Tyagi N, Srivastava SK, Bhardwaj A, Arora S, Grizzle WE, Owen LB, Singh AP, Singh S. Abstract 2011: ETV4 promotes pancreatic cancer progression and metastasis Cancer Research. 74: 2011-2011. DOI: 10.1158/1538-7445.Am2014-2011  0.384
2014 Li N, Lee K, Xi Y, Zhu B, Gary BD, Ramírez-Alcántara V, Gurpinar E, Canzoneri JC, Fajardo A, Sigler S, Piazza JT, Chen X, Andrews J, Lu W, Li Y, ... ... Grizzle WE, et al. Abstract 1773: Phosphodiesterase 10A: A novel target for selective inhibition of colon tumor cell growth and Wnt/β-catenin signaling Cancer Research. 74: 1773-1773. DOI: 10.1158/1538-7445.Am2014-1773  0.381
2014 Ramirez-Alcantara V, Schuler MA, Zhu B, Li N, Gurpinar E, Canzoneri J, Keeton A, Gary B, Russo S, Coward L, Gorman GS, Grizzle W, Chen X, Piazza GA. Abstract 1768: A novel PDE10 inhibitor suppresses tumor growth in an orthotopic mouse model of lung cancer Cancer Research. 74: 1768-1768. DOI: 10.1158/1538-7445.Am2014-1768  0.36
2014 Zhu B, Li N, Ramirez-Alcantara V, Canzoneri J, Gurpinar E, Fajardo A, Lee K, Sigler S, Gary B, Thomas M, Keeton A, Chen X, Grizzle W, Piazza G. Abstract 1761: PDE10, a novel therapeutic target for lung cancer Cancer Research. 74: 1761-1761. DOI: 10.1158/1538-7445.Am2014-1761  0.362
2013 Nguyen TL, Grizzle WE, Zhang K, Hameed O, Siegal GP, Wei S. Syndecan-1 overexpression is associated with nonluminal subtypes and poor prognosis in advanced breast cancer. American Journal of Clinical Pathology. 140: 468-74. PMID 24045542 DOI: 10.1309/Ajcpz1D8Calhdxcj  0.317
2013 Jones J, Grizzle W, Wang H, Yates C. MicroRNAs that affect prostate cancer: emphasis on prostate cancer in African Americans. Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission. 88: 410-24. PMID 23901944 DOI: 10.3109/10520295.2013.807069  0.326
2013 Gurpinar E, Grizzle WE, Piazza GA. COX-Independent Mechanisms of Cancer Chemoprevention by Anti-Inflammatory Drugs. Frontiers in Oncology. 3: 181. PMID 23875171 DOI: 10.3389/Fonc.2013.00181  0.359
2013 Li N, Xi Y, Tinsley HN, Gurpinar E, Gary BD, Zhu B, Li Y, Chen X, Keeton AB, Abadi AH, Moyer MP, Grizzle WE, Chang WC, Clapper ML, Piazza GA. Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling. Molecular Cancer Therapeutics. 12: 1848-59. PMID 23804703 DOI: 10.1158/1535-7163.Mct-13-0048  0.355
2013 Bovell LC, Shanmugam C, Putcha BD, Katkoori VR, Zhang B, Bae S, Singh KP, Grizzle WE, Manne U. The prognostic value of microRNAs varies with patient race/ethnicity and stage of colorectal cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3955-65. PMID 23719259 DOI: 10.1158/1078-0432.Ccr-12-3302  0.303
2013 Frederick PJ, Green HN, Huang JS, Egger ME, Frieboes HB, Grizzle WE, McNally LR. Chemoresistance in ovarian cancer linked to expression of microRNAs. Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission. 88: 403-9. PMID 23672416 DOI: 10.3109/10520295.2013.788736  0.308
2013 Kerr EH, Frederick PJ, Egger ME, Stockard CR, Sellers J, DellaManna D, Oelschlager DK, Amm HM, Eltoum IE, Straughn JM, Buchsbaum DJ, Grizzle WE, McNally LR. Lung resistance-related protein (LRP) expression in malignant ascitic cells as a prognostic marker for advanced ovarian serous carcinoma. Annals of Surgical Oncology. 20: 3059-65. PMID 23525731 DOI: 10.1245/S10434-013-2878-9  0.331
2013 Gurpinar E, Grizzle WE, Shacka JJ, Mader BJ, Li N, Piazza NA, Russo S, Keeton AB, Piazza GA. A novel sulindac derivative inhibits lung adenocarcinoma cell growth through suppression of Akt/mTOR signaling and induction of autophagy. Molecular Cancer Therapeutics. 12: 663-74. PMID 23443799 DOI: 10.1158/1535-7163.Mct-12-0785  0.345
2013 Huang JS, Egger ME, Grizzle WE, McNally LR. MicroRNA-100 regulates IGF1-receptor expression in metastatic pancreatic cancer cells. Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission. 88: 397-402. PMID 23373509 DOI: 10.3109/10520295.2012.762460  0.365
2013 Katkoori VR, Manne K, Vital-Reyes VS, Rodríguez-Burford C, Shanmugam C, Sthanam M, Manne U, Chatla C, Abdulkadir SA, Grizzle WE. Selective COX-2 inhibitor (celecoxib) decreases cellular growth in prostate cancer cell lines independent of p53 Biotechnic and Histochemistry. 88: 38-46. PMID 23167625 DOI: 10.3109/10520295.2012.724713  0.344
2013 Tinsley HN, Grizzle WE, Abadi A, Keeton A, Zhu B, Xi Y, Piazza GA. New NSAID targets and derivatives for colorectal cancer chemoprevention. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 191: 105-20. PMID 22893202 DOI: 10.1007/978-3-642-30331-9_6  0.361
2013 Adams G, Mehrabi S, Vatcharapijarn Y, Iyamu OI, Akwe JA, Grizzle WE, Yao X, Aikhionbare FO. Frequencies of mtDNA mutations in primary tissue of colorectal adenopolyps Frontiers in Bioscience - Elite. 5: 809-813. DOI: 10.2741/E661  0.309
2013 Klepczyk LC, Wei S, Brazelton JD, Keene KS, Bonner JA, LoBuglio AF, Forero A, Grizzle WE, Yang ES. Correlation between poly (ADP-ribose) polymerase (PARP) and phospho-p65 expression in human breast cancer. Journal of Clinical Oncology. 31: 623-623. DOI: 10.1200/Jco.2013.31.15_Suppl.623  0.382
2013 Gurpinar E, Grizzle WE, Shacka JJ, Li N, Keeton AB, Piazza GA. Abstract 587: A novel non-COX-inhibitory sulindac derivative induces autophagic cell death by inhibiting Akt signaling in lung cancer cells. Cancer Research. 73: 587-587. DOI: 10.1158/1538-7445.Am2013-587  0.366
2013 Huang JS, Egger M, Grizzle WE, McNally LR. Abstract 5344: IGF1-receptor expression is regulated by miR-100 in metastatic pancreatic cancer cells. Cancer Research. 73: 5344-5344. DOI: 10.1158/1538-7445.Am2013-5344  0.316
2013 Singh R, Gupta P, Grizzle WE, Lillard JW, Singh S. Abstract 5121: Differential expression of CC chemokine receptor-9 in prostate cancer. Cancer Research. 73: 5121-5121. DOI: 10.1158/1538-7445.Am2013-5121  0.375
2013 Arora S, Bhardwaj A, Singh S, Srivastava SK, McClellan S, Grizzle WE, Owen LB, Singh AP. Abstract 4794: An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through upregulation of CXCR4. Cancer Research. 73: 4794-4794. DOI: 10.1158/1538-7445.Am2013-4794  0.37
2013 Cai G, Kerr EH, Hu M, Yang Y, Buchsbaum DJ, Grizzle WE, Ding Q. Abstract 4013: S100A4 promotes cell migration and growth through focal adhesion kinase and Src mediated dual signaling pathways in pancreatic cancer cells. Cancer Research. 73: 4013-4013. DOI: 10.1158/1538-7445.Am2013-4013  0.377
2013 Srivastava SK, Singh S, Bhardwaj A, Arora S, McClellan S, Grizzle WE, Singh AP. Abstract 3882: Myb contributes to pancreatic cancer growth and metastasis. Cancer Research. 73: 3882-3882. DOI: 10.1158/1538-7445.Am2013-3882  0.326
2013 Bhardwaj A, Singh S, Srivastava SK, Arora S, Hyde SJ, Honkanen RE, Grizzle WE, Singh AP. Abstract 3861: Downregulation of protein phosphatase 2A promotes prostate cancer progression and metastasis. Cancer Research. 73: 3861-3861. DOI: 10.1158/1538-7445.Am2013-3861  0.395
2013 Li N, Xi Y, Tinsley HN, Gurpinar E, Gary BD, Zhu B, Li Y, Keeton AB, Grizzle WE, Piazza GA. Abstract 3659: Next generation sulindac. Cancer Research. 73: 3659-3659. DOI: 10.1158/1538-7445.Am2013-3659  0.376
2013 Srivastava SK, Tyagi N, Kaur G, Arora S, Bhardwaj A, Grizzle WE, Singh AP, Singh S. Abstract 3120: Evidence supporting a role of ETV4 in pancreatic cancer pathogenesis. Cancer Research. 73: 3120-3120. DOI: 10.1158/1538-7445.Am2013-3120  0.311
2013 Theodore S, Davis M, Rhim J, Grizzle W, Turner T, Yates C. Abstract 3060: MicroRNA expression profiling in African American and Caucasian prostate cancer. Cancer Research. 73: 3060-3060. DOI: 10.1158/1538-7445.Am2013-3060  0.353
2013 Kaur G, Srivastava SK, Arora S, Bhardwaj A, McClellan S, Scammell JG, Grizzle WE, Owen LB, Fodstad O, Singh AP, Singh S. Abstract 2709: Functional Role of FKBP51 in malignant progression of melanoma. Cancer Research. 73: 2709-2709. DOI: 10.1158/1538-7445.Am2013-2709  0.403
2013 Li N, Lee K, Xi Y, Zhu B, Gary BD, Ramirez-Alcantara V, Gurpinar E, Canzoneri J, Fajardo A, Sigler S, Piazza JT, Chen X, Andrews J, Thomas M, Lu W, ... ... Grizzle WE, et al. Abstract C182: Phosphodiesterase 10: A novel cancer target. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C182  0.398
2013 Klepczyk L, Wei S, Brazelton J, Keene K, Li Y, Bonner J, Forero A, LoBuglio A, Grizzle W, Yang E. Abstract B37: Increased expression of poly (ADP-ribose) polymerase (PARP) and phospho-p65 in human HER2+ breast cancer Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-B37  0.383
2012 Kojima K, Bowersock GJ, Kojima C, Klug CA, Grizzle WE, Mobley JA. Validation of a robust proteomic analysis carried out on formalin-fixed paraffin-embedded tissues of the pancreas obtained from mouse and human. Proteomics. 12: 3393-402. PMID 22997103 DOI: 10.1002/Pmic.201100663  0.313
2012 Singh AP, Arora S, Bhardwaj A, Srivastava SK, Kadakia MP, Wang B, Grizzle WE, Owen LB, Singh S. CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor κB: implications for bidirectional tumor-stromal interactions. The Journal of Biological Chemistry. 287: 39115-24. PMID 22995914 DOI: 10.1074/Jbc.M112.409581  0.397
2012 Jones J, Wang H, Zhou J, Hardy S, Turner T, Austin D, He Q, Wells A, Grizzle WE, Yates C. Nuclear Kaiso indicates aggressive prostate cancers and promotes migration and invasiveness of prostate cancer cells. The American Journal of Pathology. 181: 1836-46. PMID 22974583 DOI: 10.1016/J.Ajpath.2012.08.008  0.405
2012 Grunda JM, Steg AD, He Q, Steciuk MR, Byan-Parker S, Johnson MR, Grizzle WE. Differential expression of breast cancer-associated genes between stage- and age-matched tumor specimens from African- and Caucasian-American Women diagnosed with breast cancer. Bmc Research Notes. 5: 248. PMID 22616718 DOI: 10.1186/1756-0500-5-248  0.324
2012 Whitt JD, Li N, Tinsley HN, Chen X, Zhang W, Li Y, Gary BD, Keeton AB, Xi Y, Abadi AH, Grizzle WE, Piazza GA. A novel sulindac derivative that potently suppresses colon tumor cell growth by inhibiting cGMP phosphodiesterase and β-catenin transcriptional activity. Cancer Prevention Research (Philadelphia, Pa.). 5: 822-33. PMID 22556201 DOI: 10.1158/1940-6207.Capr-11-0559  0.366
2012 Srivastava SK, Bhardwaj A, Singh S, Arora S, McClellan S, Grizzle WE, Reed E, Singh AP. Myb overexpression overrides androgen depletion-induced cell cycle arrest and apoptosis in prostate cancer cells, and confers aggressive malignant traits: potential role in castration resistance. Carcinogenesis. 33: 1149-57. PMID 22431717 DOI: 10.1093/Carcin/Bgs134  0.374
2012 Katayama H, Wang J, Treekitkarnmongkol W, Kawai H, Sasai K, Zhang H, Wang H, Adams HP, Jiang S, Chakraborty SN, Suzuki F, Arlinghaus RB, Liu J, Mobley JA, Grizzle WE, et al. Aurora kinase-A inactivates DNA damage-induced apoptosis and spindle assembly checkpoint response functions of p73. Cancer Cell. 21: 196-211. PMID 22340593 DOI: 10.1016/J.Ccr.2011.12.025  0.301
2012 Meredith R, You Z, Alvarez R, Partridge E, Grizzle W, LoBuglio A. Predictors of long-term outcome from intraperitoneal radioimmunotherapy for ovarian cancer. Cancer Biotherapy & Radiopharmaceuticals. 27: 36-40. PMID 22239432 DOI: 10.1089/Cbr.2011.1111  0.326
2012 Wang H, Jones J, Turner T, He QP, Hardy S, Grizzle WE, Welch DR, Yates C. Clinical and biological significance of KISS1 expression in prostate cancer. The American Journal of Pathology. 180: 1170-8. PMID 22226740 DOI: 10.1016/J.Ajpath.2011.11.020  0.404
2012 Deng Z, Cheng Z, Xiang X, Yan J, Zhuang X, Liu C, Jiang H, Ju S, Zhang L, Grizzle W, Mobley J, Roman J, Miller D, Zhang HG. Tumor cell cross talk with tumor-associated leukocytes leads to induction of tumor exosomal fibronectin and promotes tumor progression. The American Journal of Pathology. 180: 390-8. PMID 22067905 DOI: 10.1016/J.Ajpath.2011.09.023  0.342
2012 Piazza GA, Li N, Bernard GD, Chen X, Keeton AB, Xi Y, Zhu B, Zhang W, Fajardo A, Ramirez V, Sigler S, Lee K, Cawthon C, Gurpinar E, Brownby MA, ... ... Grizzle W, et al. Abstract B59: Cyclic GMP phosphodiesterase: A molecular target for cancer chemoprevention Cancer Prevention Research. 5: B59-B59. DOI: 10.1158/1940-6207.Prev-12-B59  0.393
2012 McNally LR, Kerr EH, Oelschlager D, Stockard C, Grizzle WE. Abstract B11: miRNA expression differs between African American and European American patients with pancreatic adenocarcinoma. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-B11  0.335
2012 Srivastava SK, Bhardwaj A, Arora S, Singh S, McClellan S, Wang B, Grizzle WE, Singh AP. Abstract LB-468: miR-345 downregulation is associated with apoptosis resistance in pancreatic cancer: therapeutic implications Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-468  0.315
2012 Gurpinar E, Grizzle WE, Liu Y, Shacka JJ, Keeton AB, Piazza GA. Abstract LB-355: A novel non-COX-inhibitory sulindac derivative induces autophagic cell death in lung adenocarcinoma cells Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-355  0.35
2012 Srivastava SK, Arora S, Bhardwaj A, Scammell JG, Owen LB, Grizzle WE, Singh AP, Singh S. Abstract 84: Evidence supporting a role of FKBP51 in melanoma pathogenesis Cancer Research. 72: 84-84. DOI: 10.1158/1538-7445.Am2012-84  0.362
2012 Tinsley HN, Gary BD, Whitt J, Zhang W, Chen X, Keeton AB, Grubbs CJ, Grizzle WE, Piazza GA. Abstract 570: Breast cancer chemopreventive activity of a novel amide derivative of sulindac involves inhibition of PDE5, activation of PKG, and attenuation of Wnt/β-catenin signaling Cancer Research. 72: 570-570. DOI: 10.1158/1538-7445.Am2012-570  0.391
2012 Ludwig MR, Kojima K, Grizzle W, Mobley JA, Klug CA. Abstract 4807: Identification of pre-invasive pancreatic cancer serum biomarkers using genetically engineered mouse models and mass spectrometry techniques Cancer Research. 72: 4807-4807. DOI: 10.1158/1538-7445.Am2012-4807  0.318
2012 Katkoori VR, Choudhary S, Butler AR, Shanmugam C, Bovell LL, Samuel T, Athar M, Grizzle WE, Manne U. Abstract 4156: Interaction between therabphillin-3A-likegene and phosphorylation of mammalian target of rapamycin (mTOR) in colorectal cancer Cancer Research. 72: 4156-4156. DOI: 10.1158/1538-7445.Am2012-4156  0.37
2012 Bhardwaj A, Srivastava SK, Singh S, Arora S, Honkanen RE, Grizzle WE, Reed E, Singh AP. Abstract 3991: Protein phosphatase 2A (PP2A) downregulation is associated with androgen-independent and aggressive phenotypes in prostate cancer Cancer Research. 72: 3991-3991. DOI: 10.1158/1538-7445.Am2012-3991  0.394
2012 Singh R, Grizzle WE, Singh S, Lillard JW. Abstract 3649: Expression of CXCR5 and its natural ligand CXCL13 in ovarian cancer Cancer Research. 72: 3649-3649. DOI: 10.1158/1538-7445.Am2012-3649  0.408
2012 Otali D, He Q, Stockard CR, Grizzle WE. Abstract 3189: Preservation of immunorecognition by the transfer of cells from 10% neutral buffered formalin to 70% ethanol Cancer Research. 72: 3189-3189. DOI: 10.1158/1538-7445.Am2012-3189  0.323
2012 Green H, Grizzle WE, Rosenthal EL, Mirov SB, McNally LR. Abstract 1972: Active targeting, fluorescence imaging, and NIR photothermal therapy of malignant tumors Cancer Research. 72: 1972-1972. DOI: 10.1158/1538-7445.Am2012-1972  0.338
2012 Vaklavas C, Meng Z, White EL, Rasmussen L, Maddry JA, Nebane-Akah M, Grizzle WE, Zinn KR, Frost AR, Stockard CR, Samuel SL, Everts M, Whitley RJ, Blume SW. Abstract 1816: Blocking synthesis of oncogenic proteins in breast tumor cells through pharmacologic inhibition of the IRES Cancer Research. 72: 1816-1816. DOI: 10.1158/1538-7445.Am2012-1816  0.374
2012 Berg P, Ghimbovschi S, Grizzle W, Nguyen T. Abstract P2-05-22: Preferential Activation of BP1 and c-Myc in Breast Cancer of African American Women Compared with Caucasian American Women Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P2-05-22  0.356
2012 Li R, Nguyen T, Grizzle W, Hameed O, Siegal GP, Wei S. Expression of Receptor Activator of Nuclear Factor kB Ligand (RANKL) in Breast Cancer Is Inversely Correlated With the Triple-Negative Phenotype and Brain Metastatic Potential American Journal of Clinical Pathology. 138. DOI: 10.1093/Ajcp/138.Suppl2.329  0.311
2011 Srivastava SK, Bhardwaj A, Singh S, Arora S, Wang B, Grizzle WE, Singh AP. MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cells. Carcinogenesis. 32: 1832-9. PMID 21983127 DOI: 10.1093/Carcin/Bgr223  0.316
2011 Singh R, Stockard CR, Grizzle WE, Lillard JW, Singh S. Expression and histopathological correlation of CCR9 and CCL25 in ovarian cancer. International Journal of Oncology. 39: 373-81. PMID 21637913 DOI: 10.3892/Ijo.2011.1059  0.408
2011 Sherman S, Shats O, Ketcham MA, Anderson MA, Whitcomb DC, Lynch HT, Ghiorzo P, Rubinstein WS, Sasson AR, Grizzle WE, Haynatzki G, Feng J, Sherman A, Kinarsky L, Brand RE. PCCR: Pancreatic Cancer Collaborative Registry. Cancer Informatics. 10: 83-91. PMID 21552494 DOI: 10.4137/Cin.S6919  0.326
2011 Johnson-Holiday C, Singh R, Johnson EL, Grizzle WE, Lillard JW, Singh S. CCR9-CCL25 interactions promote cisplatin resistance in breast cancer cell through Akt activation in a PI3K-dependent and FAK-independent fashion. World Journal of Surgical Oncology. 9: 46. PMID 21539750 DOI: 10.1186/1477-7819-9-46  0.36
2011 Fortson WS, Kayarthodi S, Fujimura Y, Xu H, Matthews R, Grizzle WE, Rao VN, Bhat GK, Reddy ES. Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells. International Journal of Oncology. 39: 111-9. PMID 21519790 DOI: 10.3892/Ijo.2011.1014  0.367
2011 Kim H, Folks KD, Guo L, Sellers JC, Fineberg NS, Stockard CR, Grizzle WE, Buchsbaum DJ, Morgan DE, George JF, Zinn KR. Early therapy evaluation of combined cetuximab and irinotecan in orthotopic pancreatic tumor xenografts by dynamic contrast-enhanced magnetic resonance imaging. Molecular Imaging. 10: 153-67. PMID 21496446 DOI: 10.2310/7290.2010.00040  0.322
2011 Mignot G, Chalmin F, Ladoire S, Rébé C, Ghiringhelli F, Xiang X, Taylor DD, Grizzle W, Zhang H. Tumor exosome-mediated MDSC activation. American Journal of Pathology. 178: 1403-1405. PMID 21356390 DOI: 10.1016/J.Ajpath.2010.11.078  0.301
2011 Qin Y, Xu J, Aysola K, Begum N, Reddy V, Chai Y, Grizzle WE, Partridge EE, Reddy ES, Rao VN. Ubc9 mediates nuclear localization and growth suppression of BRCA1 and BRCA1a proteins. Journal of Cellular Physiology. 226: 3355-67. PMID 21344391 DOI: 10.1002/Jcp.22695  0.33
2011 Johnson-Holiday C, Singh R, Johnson E, Singh S, Stockard CR, Grizzle WE, Lillard JW. CCL25 mediates migration, invasion and matrix metalloproteinase expression by breast cancer cells in a CCR9-dependent fashion. International Journal of Oncology. 38: 1279-85. PMID 21344163 DOI: 10.3892/Ijo.2011.953  0.379
2011 Brand RE, Nolen BM, Zeh HJ, Allen PJ, Eloubeidi MA, Goldberg M, Elton E, Arnoletti JP, Christein JD, Vickers SM, Langmead CJ, Landsittel DP, Whitcomb DC, Grizzle WE, Lokshin AE. Serum biomarker panels for the detection of pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 805-16. PMID 21325298 DOI: 10.1158/1078-0432.Ccr-10-0248  0.314
2011 Walsh SB, Xu J, Xu H, Kurundkar AR, Maheshwari A, Grizzle WE, Timares L, Huang CC, Kopelovich L, Elmets CA, Athar M. Cyclosporine a mediates pathogenesis of aggressive cutaneous squamous cell carcinoma by augmenting epithelial-mesenchymal transition: role of TGFβ signaling pathway. Molecular Carcinogenesis. 50: 516-27. PMID 21308804 DOI: 10.1002/Mc.20744  0.36
2011 Zhang HG, Grizzle WE. Exosomes and cancer: a newly described pathway of immune suppression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 959-64. PMID 21224375 DOI: 10.1158/1078-0432.Ccr-10-1489  0.358
2011 Balasenthil S, Chen N, Lott ST, Chen J, Carter J, Grizzle WE, Frazier ML, Sen S, Killary AM. A migration signature and plasma biomarker panel for pancreatic adenocarcinoma. Cancer Prevention Research (Philadelphia, Pa.). 4: 137-49. PMID 21071578 DOI: 10.1158/1940-6207.Capr-10-0025  0.346
2011 Hensel JA, Chanda D, Kumar S, Sawant A, Grizzle WE, Siegal GP, Ponnazhagan S. LL-37 as a therapeutic target for late stage prostate cancer. The Prostate. 71: 659-70. PMID 20957672 DOI: 10.1002/Pros.21282  0.355
2011 Benavides MA, Hu D, Baraoidan MK, Bruno A, Du P, Lin S, Yang W, Bland KI, Grizzle WE, Bosland MC. L-methionine-induced alterations in molecular signatures in MCF-7 and LNCaP cancer cells. Journal of Cancer Research and Clinical Oncology. 137: 441-53. PMID 20454975 DOI: 10.1007/S00432-010-0897-5  0.352
2011 Singh R, Singh S, Grizzle WE, Lillard JW. Abstract 5257: Expression and functional role of CXCR5 and CXCL13 in non-small cell lung carcinoma (NSCLC) Cancer Research. 71: 5257-5257. DOI: 10.1158/1538-7445.Am2011-5257  0.401
2011 Singh R, Lillard JW, Grizzle WE, Singh S. Abstract 5247: Expression and functional role of CCR9 in lung cancer Cancer Research. 71: 5247-5247. DOI: 10.1158/1538-7445.Am2011-5247  0.376
2011 Kim H, Zhai G, Shah N, Liu Z, Helman E, Knowles J, Stockard C, Grizzle W, Zhou T, Zinn K, Rosenthal E. Abstract 4575: Novel monoclonal antibody targeting EMMPRIN for pancreatic cancer therapy Cancer Research. 71: 4575-4575. DOI: 10.1158/1538-7445.Am2011-4575  0.3
2011 Sun D, Zhuang X, Grizzle W, Miller D, Zhang H. Abstract 4446: A novel nanoparticle drug delivery system: The anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes Cancer Research. 71: 4446-4446. DOI: 10.1158/1538-7445.Am2011-4446  0.314
2011 Singh S, Srivastava SK, Bhardwaj A, Owen LB, Grizzle WE, Singh AP. Abstract 4011: Evidence supporting a role of c-Myb in pancreatic cancer Cancer Research. 71: 4011-4011. DOI: 10.1158/1538-7445.Am2011-4011  0.376
2011 Nolen BM, Lomakin A, Grizzle WE, Jhala N, Eloubeidi MA, Christein JD, Arnoletti JP, Oelschlager DK, Vickers SM, Lokshin AE. Abstract 3181: The combined use of urine and serum biomarkers in early detection strategies for pancreatic cancer Cancer Research. 71: 3181-3181. DOI: 10.1158/1538-7445.Am2011-3181  0.307
2011 Shanmugam C, Salih C, Katkoori VR, Bovell LL, Callens T, Messiaen LM, Hameed O, Grizzle WE, Manne U. Abstract 2271: Single nucleotide polymorphisms inp53codon 72 is associated with grade III tumors in African Americans with breast carcinoma Cancer Research. 71: 2271-2271. DOI: 10.1158/1538-7445.Am2011-2271  0.334
2011 Ahluwalia S, Shanmugam C, Katkoori VR, Jhala NC, Sugandha SP, Grizzle WE, Manne U. Abstract 2262: The prognostic value of p53 abnormalities in colorectal cancers varies based on detection methods Cancer Research. 71: 2262-2262. DOI: 10.1158/1538-7445.Am2011-2262  0.32
2011 Srivastava SK, Bhardwaj A, Singh S, Reed E, Grizzle W, Singh AP. Abstract 2156: c-Myb promotes growth, invasion and androgen-independence of prostate cancer cells Cancer Research. 71: 2156-2156. DOI: 10.1158/1538-7445.Am2011-2156  0.374
2011 Piazza GA, Keeton AB, Tinsley HN, Gary BD, Whitt JD, Li N, Gurpinar E, Sun Y, Mathew B, Reynolds RC, Zhang W, Singh R, Coward L, Gorman G, Maxuitenko YY, ... Grizzle W, et al. Abstract 1865: Colon cancer chemopreventive properties of a non-cyclooxygenase inhibitory amide derivative of sulindac Cancer Research. 71: 1865-1865. DOI: 10.1158/1538-7445.Am2011-1865  0.369
2011 Kerr EH, Frederick PJ, Oelschlager DK, Amm H, Sellers J, Manna DD, Buchsbaum DJ, Grizzle WE, McNally LR. Abstract 1714: Chemoresistance in patients with papillary serous carcinoma of the ovary Cancer Research. 71: 1714-1714. DOI: 10.1158/1538-7445.Am2011-1714  0.362
2011 Srivastava SK, Singh S, Bhardwaj A, Grizzle WE, Singh AP. Abstract 129: miR-345 is a novel tumor suppressor microRNA in pancreatic cancer Cancer Research. 71: 129-129. DOI: 10.1158/1538-7445.Am2011-129  0.349
2011 Gaston SM, Kearney GP, Grizzle WE. Abstract A47: Prostate biopsy tissue print technologies: A practical and innovative approach to overcoming racial disparities in the datasets used for prostate cancer biomarker development Cancer Epidemiology, Biomarkers & Prevention. 20. DOI: 10.1158/1055-9965.Disp-11-A47  0.357
2011 Grizzle W, Steg A, He Q, Steciuk, Byan-Parker S, Johnson, Grunda J. P2-06-03: Differential Expression of Breast Cancer-Associated Genes between Stage- and Age-Matched Tumor Specimens from African- and Caucasian-American Women Diagnosed with Breast Cancer. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P2-06-03  0.36
2010 Piazza GA, Keeton AB, Tinsley HN, Whitt JD, Gary BD, Mathew B, Singh R, Grizzle WE, Reynolds RC. NSAIDs: Old Drugs Reveal New Anticancer Targets. Pharmaceuticals (Basel, Switzerland). 3: 1652-1667. PMID 27713322 DOI: 10.3390/Ph3051652  0.335
2010 Katkoori VR, Suarez-Cuervo C, Shanmugam C, Jhala NC, Callens T, Messiaen L, Posey J, Bumpers HL, Meleth S, Grizzle WE, Manne U. Bax expression is a candidate prognostic and predictive marker of colorectal cancer. Journal of Gastrointestinal Oncology. 1: 76-89. PMID 22811811 DOI: 10.3978/J.Issn.2078-6891.2010.019  0.328
2010 Grizzle WE, Bell WC, Sexton KC. Issues in collecting, processing and storing human tissues and associated information to support biomedical research. Cancer Biomarkers : Section a of Disease Markers. 9: 531-49. PMID 22112494 DOI: 10.3233/Cbm-2011-0183  0.313
2010 Manne U, Shanmugam C, Katkoori VR, Bumpers HL, Grizzle WE. Development and progression of colorectal neoplasia. Cancer Biomarkers : Section a of Disease Markers. 9: 235-65. PMID 22112479 DOI: 10.3233/Cbm-2011-0160  0.34
2010 Srivastava S, Grizzle WE. Biomarkers and the genetics of early neoplastic lesions. Cancer Biomarkers : Section a of Disease Markers. 9: 41-64. PMID 22112469 DOI: 10.3233/Cbm-2011-0204  0.336
2010 Grizzle WE, Srivastava S, Manne U. Translational pathology of neoplasia. Cancer Biomarkers : Section a of Disease Markers. 9: 7-20. PMID 22112467 DOI: 10.3233/Cbm-2011-0159  0.34
2010 Mehrabi S, Akwe JA, Adams G, Grizzle W, Yao X, Aikhionbare FO. Analysis of mtDNA sequence variants in colorectal adenomatous polyps Diagnostic Pathology. 5: 66-66. PMID 20929553 DOI: 10.1186/1746-1596-5-66  0.305
2010 McNally LR, Welch DR, Beck BH, Stafford LJ, Long JW, Sellers JC, Huang ZQ, Grizzle WE, Stockard CR, Nash KT, Buchsbaum DJ. KISS1 over-expression suppresses metastasis of pancreatic adenocarcinoma in a xenograft mouse model. Clinical & Experimental Metastasis. 27: 591-600. PMID 20844932 DOI: 10.1007/S10585-010-9349-5  0.371
2010 Xiang X, Liu Y, Zhuang X, Zhang S, Michalek S, Taylor DD, Grizzle W, Zhang HG. TLR2-mediated expansion of MDSCs is dependent on the source of tumor exosomes. The American Journal of Pathology. 177: 1606-10. PMID 20802178 DOI: 10.2353/Ajpath.2010.100245  0.324
2010 Johnson EL, Singh R, Singh S, Johnson-Holiday CM, Grizzle WE, Partridge EE, Lillard JW. CCL25-CCR9 interaction modulates ovarian cancer cell migration, metalloproteinase expression, and invasion. World Journal of Surgical Oncology. 8: 62. PMID 20649989 DOI: 10.1186/1477-7819-8-62  0.336
2010 Johnson EL, Singh R, Johnson-Holiday CM, Grizzle WE, Partridge EE, Lillard JW, Singh S. CCR9 interactions support ovarian cancer cell survival and resistance to cisplatin-induced apoptosis in a PI3K-dependent and FAK-independent fashion. Journal of Ovarian Research. 3: 15. PMID 20565782 DOI: 10.1186/1757-2215-3-15  0.334
2010 Liu Y, Xiang X, Zhuang X, Zhang S, Liu C, Cheng Z, Michalek S, Grizzle W, Zhang HG. Contribution of MyD88 to the tumor exosome-mediated induction of myeloid derived suppressor cells. The American Journal of Pathology. 176: 2490-9. PMID 20348242 DOI: 10.2353/Ajpath.2010.090777  0.308
2010 Blume SW, Jackson NL, Frost AR, Grizzle WE, Shcherbakov OD, Choi H, Meng Z. Northwestern profiling of potential translation-regulatory proteins in human breast epithelial cells and malignant breast tissues: evidence for pathological activation of the IGF1R IRES. Experimental and Molecular Pathology. 88: 341-52. PMID 20233590 DOI: 10.1016/J.Yexmp.2010.03.006  0.336
2010 Sharma PK, Singh R, Novakovic KR, Eaton JW, Grizzle WE, Singh S. CCR9 mediates PI3K/AKT-dependent antiapoptotic signals in prostate cancer cells and inhibition of CCR9-CCL25 interaction enhances the cytotoxic effects of etoposide. International Journal of Cancer. Journal International Du Cancer. 127: 2020-30. PMID 20127861 DOI: 10.1002/Ijc.25219  0.367
2010 Xu L, Kwon YJ, Frolova N, Steg AD, Yuan K, Johnson MR, Grizzle WE, Desmond RA, Frost AR. Gli1 promotes cell survival and is predictive of a poor outcome in ERalpha-negative breast cancer. Breast Cancer Research and Treatment. 123: 59-71. PMID 19902354 DOI: 10.1007/S10549-009-0617-5  0.386
2010 Benavides MA, Hu D, Baraoidan MK, Bruno A, Du P, Lin S, Yang W, Bland KI, Grizzle WE, Bosland MC. Abstract 658: Identification of a molecular signature after L-methionine treatment in MCF-7 and LNCaP cancer cells Cancer Research. 70: 658-658. DOI: 10.1158/1538-7445.Am10-658  0.38
2010 Kim H, Folks K, Guo L, Sellers J, Fineberg N, Stockard C, Grizzle W, Buchsbaum D, Morgan D, George J, Zinn K. Abstract 641: Early therapy assessment of cetuximab and irinotecan in orthotopic pancreatic tumor xenografts by dynamic contrast-enhanced magnetic resonance imaging Cancer Research. 70: 641-641. DOI: 10.1158/1538-7445.Am10-641  0.329
2010 Sharma PK, Singh R, Grizzle WE, Singh S. Abstract 5458: Clinical and biological significance of CCR9-CCL25 axis in prostate cancer Cancer Research. 70: 5458-5458. DOI: 10.1158/1538-7445.Am10-5458  0.413
2010 Nolen BM, Lomakin A, Bast R, Lu K, Grizzle WE, Jhala NC, Eloubeidi MA, Christein JD, Arnoletti JP, Oelschlager DK, Vickers SM, Marrangoni A, Lokshin A. Abstract 4567: Urine biomarkers outperform serum biomarkers in the diagnosis of various human cancers Cancer Research. 70: 4567-4567. DOI: 10.1158/1538-7445.Am10-4567  0.354
2010 McNally LR, Frederick PJ, Bevis KS, Sellers JC, Manna DLD, Straughn JM, Stockard CR, Grizzle WE, Buchsbaum DJ. Abstract 2688: The expression of lung resistance protein (LRP) in patient ascites predicts platinum resistance in advanced epithelial ovarian carcinoma Cancer Research. 70: 2688-2688. DOI: 10.1158/1538-7445.Am10-2688  0.358
2010 Sharma P, Singh R, Novakovic K, Grizzle W, Singh S. 1428 Significance Of Ccr9-Ccl25 Axis In Prostate Cancer Metastasis The Journal of Urology. 183. DOI: 10.1016/J.Juro.2010.02.1121  0.335
2009 Ren Y, Wu L, Frost AR, Grizzle W, Cao X, Wan M. Dual effects of TGF-beta on ERalpha-mediated estrogenic transcriptional activity in breast cancer. Molecular Cancer. 8: 111. PMID 19943940 DOI: 10.1186/1476-4598-8-111  0.328
2009 Kaliberova LN, Kusmartsev SA, Krendelchtchikova V, Stockard CR, Grizzle WE, Buchsbaum DJ, Kaliberov SA. Experimental cancer therapy using restoration of NAD+ -linked 15-hydroxyprostaglandin dehydrogenase expression. Molecular Cancer Therapeutics. 8: 3130-9. PMID 19887544 DOI: 10.1158/1535-7163.Mct-09-0270  0.398
2009 Otali D, Stockard CR, Oelschlager DK, Wan W, Manne U, Watts SA, Grizzle WE. Combined effects of formalin fixation and tissue processing on immunorecognition Fixation effects on immunostaining Biotechnic and Histochemistry. 84: 223-247. PMID 19886759 DOI: 10.3109/10520290903039094  0.315
2009 Jian B, Nagineni CN, Meleth S, Grizzle W, Bland K, Chaudry I, Raju R. Anosmin-1 involved in neuronal cell migration is hypoxia inducible and cancer regulated. Cell Cycle (Georgetown, Tex.). 8: 3770-6. PMID 19844165 DOI: 10.4161/Cc.8.22.10066  0.365
2009 Singh S, Singh R, Singh UP, Rai SN, Novakovic KR, Chung LW, Didier PJ, Grizzle WE, Lillard JW. Clinical and biological significance of CXCR5 expressed by prostate cancer specimens and cell lines. International Journal of Cancer. Journal International Du Cancer. 125: 2288-95. PMID 19610059 DOI: 10.1002/Ijc.24574  0.347
2009 Frederick PJ, Kendrick JE, Straughn JM, Della Manna DL, Oliver PG, Lin HY, Grizzle WE, Stockard CR, Alvarez RD, Zhou T, LoBuglio AF, Buchsbaum DJ. Effect of TRA-8 anti-death receptor 5 antibody in combination with chemotherapy in an ex vivo human ovarian cancer model. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. 19: 814-9. PMID 19574765 DOI: 10.1111/Igc.0B013E3181A2A003  0.312
2009 Li J, Wang Y, Yang C, Wang P, Oelschlager DK, Zheng Y, Tian DA, Grizzle WE, Buchsbaum DJ, Wan M. Polyethylene glycosylated curcumin conjugate inhibits pancreatic cancer cell growth through inactivation of Jab1. Molecular Pharmacology. 76: 81-90. PMID 19395473 DOI: 10.1124/Mol.109.054551  0.379
2009 Singh S, Singh R, Sharma PK, Singh UP, Rai SN, Chung LW, Cooper CR, Novakovic KR, Grizzle WE, Lillard JW. Serum CXCL13 positively correlates with prostatic disease, prostate-specific antigen and mediates prostate cancer cell invasion, integrin clustering and cell adhesion. Cancer Letters. 283: 29-35. PMID 19375853 DOI: 10.1016/J.Canlet.2009.03.022  0.337
2009 Liu K, Bellam N, Lin HY, Wang B, Stockard CR, Grizzle WE, Lin WC. Regulation of p53 by TopBP1: a potential mechanism for p53 inactivation in cancer. Molecular and Cellular Biology. 29: 2673-93. PMID 19289498 DOI: 10.1128/Mcb.01140-08  0.353
2009 Xiang X, Poliakov A, Liu C, Liu Y, Deng ZB, Wang J, Cheng Z, Shah SV, Wang GJ, Zhang L, Grizzle WE, Mobley J, Zhang HG. Induction of myeloid-derived suppressor cells by tumor exosomes. International Journal of Cancer. Journal International Du Cancer. 124: 2621-33. PMID 19235923 DOI: 10.1002/Ijc.24249  0.329
2009 Shanmugam C, Katkoori VR, Jhala NC, Grizzle WE, Manne U. Immunohistochemical expression of rabphilin-3A-like (Noc2) in normal and tumor tissues of human endocrine pancreas. Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission. 84: 39-45. PMID 19212825 DOI: 10.1080/10520290902738878  0.341
2009 Singh S, Bond VC, Powell M, Singh UP, Bumpers HL, Grizzle WE, Lillard JW. CXCR4-gp120-IIIB interactions induce caspase-mediated apoptosis of prostate cancer cells and inhibit tumor growth Molecular Cancer Therapeutics. 8: 178-184. PMID 19139127 DOI: 10.1158/1535-7163.Mct-08-0643  0.389
2009 Sharma PK, Singh R, Eaton JW, Lillard JW, Novakovic KR, Grizzle WE, Chung LWk, Singh S. Ccl25 Blockade Inhibits Anti-Apoptotic Signals In Prostate Cancer Cells And Enhances The Efficacy Of Etoposide The Journal of Urology. 181: 398-399. DOI: 10.1016/S0022-5347(09)61131-9  0.345
2008 Newman JR, Bohannon IA, Zhang W, Skipper JB, Grizzle WE, Rosenthal EL. Modulation of tumor cell growth in vivo by extracellular matrix metalloprotease inducer. Archives of Otolaryngology--Head & Neck Surgery. 134: 1218-24. PMID 19015455 DOI: 10.1001/Archotol.134.11.1218  0.365
2008 Kim H, Morgan DE, Buchsbaum DJ, Zeng H, Grizzle WE, Warram JM, Stockard CR, McNally LR, Long JW, Sellers JC, Forero A, Zinn KR. Early therapy evaluation of combined anti-death receptor 5 antibody and gemcitabine in orthotopic pancreatic tumor xenografts by diffusion-weighted magnetic resonance imaging. Cancer Research. 68: 8369-76. PMID 18922909 DOI: 10.1158/0008-5472.Can-08-1771  0.303
2008 Wang D, Stockard CR, Harkins L, Lott P, Salih C, Yuan K, Buchsbaum D, Hashim A, Zayzafoon M, Hardy RW, Hameed O, Grizzle W, Siegal GP. Immunohistochemistry in the evaluation of neovascularization in tumor xenografts. Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission. 83: 179-89. PMID 18846440 DOI: 10.1080/10520290802451085  0.312
2008 Aikhionbare FO, Mehrabi S, Thompson W, Yao X, Grizzle W, Partridge E. mtDNA sequence variants in subtypes of epithelial ovarian cancer stages in relation to ethnic and age difference Diagnostic Pathology. 3: 32-32. PMID 18662401 DOI: 10.1186/1746-1596-3-32  0.307
2008 Kendrick JE, Straughn JM, Oliver PG, Wang W, Nan L, Grizzle WE, Stockard CR, Alvarez RD, Buchsbaum DJ. Anti-tumor activity of the TRA-8 anti-DR5 antibody in combination with cisplatin in an ex vivo human cervical cancer model. Gynecologic Oncology. 108: 591-7. PMID 18177927 DOI: 10.1016/J.Ygyno.2007.11.039  0.328
2008 Shanmugam C, Katkoori VR, Jhala NC, Grizzle WE, Siegal GP, Manne U. p53 Nuclear accumulation and Bcl-2 expression in contiguous adenomatous components of colorectal adenocarcinomas predict aggressive tumor behavior. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 56: 305-12. PMID 18071066 DOI: 10.1369/Jhc.7A7362.2007  0.303
2008 McLerran D, Grizzle WE, Feng Z, Bigbee WL, Banez LL, Cazares LH, Chan DW, Diaz J, Izbicka E, Kagan J, Malehorn DE, Malik G, Oelschlager D, Partin A, Randolph T, et al. Analytical validation of serum proteomic profiling for diagnosis of prostate cancer: sources of sample bias. Clinical Chemistry. 54: 44-52. PMID 17981926 DOI: 10.1373/Clinchem.2007.091470  0.311
2007 Derosier LC, Vickers SM, Zinn KR, Huang Z, Wang W, Grizzle WE, Sellers J, Stockard CR, Zhou T, Oliver PG, Arnoletti P, Lobuglio AF, Buchsbaum DJ. TRA-8 anti-DR5 monoclonal antibody and gemcitabine induce apoptosis and inhibit radiologically validated orthotopic pancreatic tumor growth. Molecular Cancer Therapeutics. 6: 3198-207. PMID 18089714 DOI: 10.1158/1535-7163.Mct-07-0299  0.373
2007 Steg A, Vickers SM, Eloubeidi M, Wang W, Eltoum IA, Grizzle WE, Saif MW, Lobuglio AF, Frost AR, Johnson MR. Hedgehog pathway expression in heterogeneous pancreatic adenocarcinoma: implications for the molecular analysis of clinically available biopsies. Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B. 16: 229-37. PMID 18043287 DOI: 10.1097/Pdm.0B013E31811Edc7E  0.361
2007 Grizzle WE, Xu X, Zhang S, Stockard CR, Liu C, Yu S, Wang J, Mountz JD, Zhang HG. Age-related increase of tumor susceptibility is associated with myeloid-derived suppressor cell mediated suppression of T cell cytotoxicity in recombinant inbred BXD12 mice. Mechanisms of Ageing and Development. 128: 672-80. PMID 18036633 DOI: 10.1016/J.Mad.2007.10.003  0.304
2007 Chakrabarti R, Jones JL, Oelschlager DK, Tapia T, Tousson A, Grizzle WE. Phosphorylated LIM kinases colocalize with gamma-tubulin in centrosomes during early stages of mitosis. Cell Cycle (Georgetown, Tex.). 6: 2944-52. PMID 18000399 DOI: 10.4161/Cc.6.23.4957  0.311
2007 Phillips PA, Dudeja V, McCarroll JA, Borja-Cacho D, Dawra RK, Grizzle WE, Vickers SM, Saluja AK. Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70. Cancer Research. 67: 9407-16. PMID 17909050 DOI: 10.1158/0008-5472.Can-07-1077  0.382
2007 DeRosier LC, Buchsbaum DJ, Oliver PG, Huang ZQ, Sellers JC, Grizzle WE, Wang W, Zhou T, Zinn KR, Long JW, Vickers SM. Combination treatment with TRA-8 anti death receptor 5 antibody and CPT-11 induces tumor regression in an orthotopic model of pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 5535s-5543s. PMID 17875786 DOI: 10.1158/1078-0432.Ccr-07-1075  0.348
2007 Chhieng DC, Rodriguez-Burford C, Meleth S, Grizzle WE, Ferguson SM. Assessment of biomarker expression in predicting pathologic response to neoadjuvant chemotherapy in patients with locally advanced breast cancer. The Breast Journal. 13: 534-5. PMID 17760684 DOI: 10.1111/J.1524-4741.2007.00483.X  0.316
2007 Huffman DM, Grizzle WE, Bamman MM, Kim JS, Eltoum IA, Elgavish A, Nagy TR. SIRT1 is significantly elevated in mouse and human prostate cancer. Cancer Research. 67: 6612-8. PMID 17638871 DOI: 10.1158/0008-5472.Can-07-0085  0.396
2007 Davila M, Jhala D, Ghosh D, Grizzle WE, Chakrabarti R. Expression of LIM kinase 1 is associated with reversible G1/S phase arrest, chromosomal instability and prostate cancer. Molecular Cancer. 6: 40. PMID 17559677 DOI: 10.1186/1476-4598-6-40  0.375
2007 Zhang HG, Kim H, Liu C, Yu S, Wang J, Grizzle WE, Kimberly RP, Barnes S. Curcumin reverses breast tumor exosomes mediated immune suppression of NK cell tumor cytotoxicity. Biochimica Et Biophysica Acta. 1773: 1116-23. PMID 17555831 DOI: 10.1016/J.Bbamcr.2007.04.015  0.348
2007 Yu S, Liu C, Su K, Wang J, Liu Y, Zhang L, Li C, Cong Y, Kimberly R, Grizzle WE, Falkson C, Zhang HG. Tumor exosomes inhibit differentiation of bone marrow dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 6867-75. PMID 17513735 DOI: 10.4049/Jimmunol.178.11.6867  0.326
2007 Estes JM, Oliver PG, Straughn JM, Zhou T, Wang W, Grizzle WE, Alvarez RD, Stockard CR, LoBuglio AF, Buchsbaum DJ. Efficacy of anti-death receptor 5 (DR5) antibody (TRA-8) against primary human ovarian carcinoma using a novel ex vivo tissue slice model. Gynecologic Oncology. 105: 291-8. PMID 17303227 DOI: 10.1016/J.Ygyno.2006.12.033  0.324
2007 Liu C, Yu S, Kappes J, Wang J, Grizzle WE, Zinn KR, Zhang HG. Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host. Blood. 109: 4336-42. PMID 17244679 DOI: 10.1182/Blood-2006-09-046201  0.325
2007 Benavides MA, Oelschlager DK, Zhang HG, Stockard CR, Vital-Reyes VS, Katkoori VR, Manne U, Wang W, Bland KI, Grizzle WE. Methionine inhibits cellular growth dependent on the p53 status of cells. American Journal of Surgery. 193: 274-83. PMID 17236862 DOI: 10.1016/J.Amjsurg.2006.07.016  0.316
2007 Qiu T, Grizzle WE, Oelschlager DK, Shen X, Cao X. Control of prostate cell growth: BMP antagonizes androgen mitogenic activity with incorporation of MAPK signals in Smad1. The Embo Journal. 26: 346-57. PMID 17183365 DOI: 10.1038/Sj.Emboj.7601499  0.335
2007 Huisman A, Ploeger LS, Dullens HFJ, Jonges TN, Belien JAM, Meijer GA, Poulin N, Grizzle WE, Van Diest PJ. Discrimination between benign and malignant prostate tissue using chromatin texture analysis in 3-D by confocal laser scanning microscopy Prostate. 67: 248-254. PMID 17075809 DOI: 10.1002/Pros.20507  0.305
2007 Huffman DM, Grizzle WE, Bamman MM, Kim JS, Eltoum IA, Elgavish A, Nagy TR. Erratum: SIRT1 is significantly elevated in mouse and human prostate cancer (Cancer Research (2007) 67, (6612-6618)) Cancer Research. 67. DOI: 10.1158/0008-5472.Can-67-17-Cor2  0.353
2006 Vital-Reyes V, Rodríguez-Burford C, Chhieng DC, Oelschlager DK, Reyes-Fuentes A, Barnes M, Grizzle WE. Celecoxib Inhibits Cellular Growth, Decreases Ki-67 Expression and Modifies Apoptosis in Ovarian Cancer Cell Lines Archives of Medical Research. 37: 689-695. PMID 16824926 DOI: 10.1016/J.Arcmed.2005.11.014  0.348
2006 Grunda JM, Nabors LB, Palmer CA, Chhieng DC, Steg A, Mikkelsen T, Diasio RB, Zhang K, Allison D, Grizzle WE, Wang W, Gillespie GY, Johnson MR. Increased expression of thymidylate synthetase (TS), ubiquitin specific protease 10 (USP10) and survivin is associated with poor survival in glioblastoma multiforme (GBM). Journal of Neuro-Oncology. 80: 261-74. PMID 16773218 DOI: 10.1007/S11060-006-9191-4  0.319
2006 Steg A, Wang W, Blanquicett C, Grunda JM, Eltoum IA, Wang K, Buchsbaum DJ, Vickers SM, Russo S, Diasio RB, Frost AR, LoBuglio AF, Grizzle WE, Johnson MR. Multiple gene expression analyses in paraffin-embedded tissues by TaqMan low-density array: Application to hedgehog and Wnt pathway analysis in ovarian endometrioid adenocarcinoma. The Journal of Molecular Diagnostics : Jmd. 8: 76-83. PMID 16436637 DOI: 10.2353/Jmoldx.2006.040402  0.332
2006 Liu C, Yu S, Zinn K, Wang J, Zhang L, Jia Y, Kappes JC, Barnes S, Kimberly RP, Grizzle WE, Zhang HG. Murine mammary carcinoma exosomes promote tumor growth by suppression of NK cell function. Journal of Immunology (Baltimore, Md. : 1950). 176: 1375-85. PMID 16424164 DOI: 10.4049/Jimmunol.176.3.1375  0.343
2006 Straughn JM, Oliver PG, Zhou T, Wang W, Alvarez RD, Grizzle WE, Buchsbaum DJ. Anti-tumor activity of TRA-8 anti-death receptor 5 (DR5) monoclonal antibody in combination with chemotherapy and radiation therapy in a cervical cancer model. Gynecologic Oncology. 101: 46-54. PMID 16271751 DOI: 10.1016/J.Ygyno.2005.09.053  0.311
2006 Manne U, Suarez-Cuervo C, Jhala NC, Posey J, Herring CB, Meleth S, Grizzle WE. Phenotypic expression of Bax is a predictive marker of 5-fluorouracil treatment in colorectal cancer Journal of Clinical Oncology. 24: 3605-3605. DOI: 10.1200/Jco.2006.24.18_Suppl.3605  0.348
2006 Singh S, Singh R, Singh UP, Kimbro KS, Cooper CR, Chung LWK, Datta MW, Didier PJ, Grizzle WE, Lillard JW. 824: CXCR5-CXCL13 Expression Regulates Cellular Mechanisms Involved in Prostate Cancer Cell Migration, Invasion and Clinically Correlates with Prostate Cancer Progression The Journal of Urology. 175: 266-266. DOI: 10.1016/S0022-5347(18)33060-X  0.358
2005 Barnes MN, Chhieng DF, Dreher M, Jones JL, Grizzle WE, Jones L, Talley L, Partridge EE. Feasibility of performing chemoprevention trials in women at elevated risk of ovarian carcinoma: initial examination of celecoxib as a chemopreventive agent. Gynecologic Oncology. 98: 376-82. PMID 15993933 DOI: 10.1016/J.Ygyno.2005.05.022  0.315
2005 Stonecypher MS, Byer SJ, Grizzle WE, Carroll SL. Activation of the neuregulin-1/ErbB signaling pathway promotes the proliferation of neoplastic Schwann cells in human malignant peripheral nerve sheath tumors. Oncogene. 24: 5589-605. PMID 15897877 DOI: 10.1038/Sj.Onc.1208730  0.34
2005 Li Q, Wu L, Oelschlager DK, Wan M, Stockard CR, Grizzle WE, Wang N, Chen H, Sun Y, Cao X. Smad4 inhibits tumor growth by inducing apoptosis in estrogen receptor-alpha-positive breast cancer cells. The Journal of Biological Chemistry. 280: 27022-8. PMID 15886208 DOI: 10.1074/Jbc.M505071200  0.372
2005 Alexander D, Jhala N, Chatla C, Steinhauer J, Funkhouser E, Coffey CS, Grizzle WE, Manne U. High-grade tumor differentiation is an indicator of poor prognosis in African Americans with colonic adenocarcinomas. Cancer. 103: 2163-70. PMID 15816050 DOI: 10.1002/Cncr.21021  0.303
2005 Bumpers HL, Huang MB, Powell M, Grizzle WE, Lillard JW, Okoli J, Bond VC. Effects of HIV-1 Nef, a cytotoxic viral protein, on the growth of primary colorectal cancer. Cancer Biology & Therapy. 4: 65-9. PMID 15662115 DOI: 10.4161/Cbt.4.1.1377  0.34
2005 Semmes OJ, Feng Z, Adam BL, Banez LL, Bigbee WL, Campos D, Cazares LH, Chan DW, Grizzle WE, Izbicka E, Kagan J, Malik G, McLerran D, Moul JW, Partin A, et al. Evaluation of serum protein profiling by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry for the detection of prostate cancer: I. Assessment of platform reproducibility. Clinical Chemistry. 51: 102-12. PMID 15613711 DOI: 10.1373/Clinchem.2004.038950  0.35
2005 Mahendra G, Kumar S, Isayeva T, Mahasreshti PJ, Curiel DT, Stockardt CR, Grizzle WE, Alapati V, Singh R, Siegal GP, Meleth S, Ponnazhagan S. Antiangiogenic cancer gene therapy by adeno-associated virus 2-mediated stable expression of the soluble FMS-like tyrosine kinase-1 receptor. Cancer Gene Therapy. 12: 26-34. PMID 15359287 DOI: 10.1038/Sj.Cgt.7700754  0.354
2005 Ferguson SM, Rodriguez-Burford C, Chhieng DC, Grizzle WE. The effects of sequential chemotherapy on locally advanced breast cancer (LABC) in African-Americans Journal of Clinical Oncology. 23: 901-901. DOI: 10.1200/Jco.2005.23.16_Suppl.901  0.322
2005 Everts M, Kim-Park S, Preuss MA, Passineau MJ, Glasgow JN, Pereboev AV, Mahasreshti PJ, Grizzle WE, Reynolds PN, Curiel DT. 1017. Selective Induction of Tumor-Associated Antigens in Murine Pulmonary Vasculature Using Double-Targeted Adenoviral Vectors Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.564  0.336
2004 Singh S, Singh UP, Stiles JK, Grizzle WE, Lillard JW. Expression and functional role of CCR9 in prostate cancer cell migration and invasion. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 8743-50. PMID 15623660 DOI: 10.1158/1078-0432.Ccr-04-0266  0.396
2004 Kaliberov SA, Kaliberova LN, Stockard CR, Grizzle WE, Buchsbaum DJ. Adenovirus-mediated FLT1-targeted proapoptotic gene therapy of human prostate cancer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 1059-70. PMID 15564138 DOI: 10.1016/J.Ymthe.2004.08.024  0.393
2004 Singh S, Singh UP, Grizzle WE, Lillard JW. CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion. Laboratory Investigation; a Journal of Technical Methods and Pathology. 84: 1666-76. PMID 15467730 DOI: 10.1038/Labinvest.3700181  0.349
2004 Grizzle WE, Semmes OJ, Basler J, Izbicka E, Feng Z, Kagan J, Adam BL, Troyer D, Srivastava S, Thornquist M, Zhang Z, Thompson IM. The early detection research network surface-enhanced laser desorption and ionization prostate cancer detection study: A study in biomarker validation in genitourinary oncology. Urologic Oncology. 22: 337-43. PMID 15283893 DOI: 10.1016/J.Urolonc.2004.04.008  0.339
2004 Grizzle WE, Meleth S. Clarification in the point/counterpoint discussion related to surface-enhanced laser desorption/ionization time-of-flight mass spectrometric identification of patients with adenocarcinomas of the prostate. Clinical Chemistry. 50: 1475-6; author reply. PMID 15277364 DOI: 10.1373/Clinchem.2004.033456  0.301
2004 Chhieng DC, Frost AR, Niwas S, Weiss H, Grizzle WE, Beeken S. Intratumor heterogeneity of biomarker expression in breast carcinomas Biotechnic and Histochemistry. 79: 25-36. PMID 15223751 DOI: 10.1080/10520290410001715237  0.349
2004 Dulaimi E, Caceres IId, Uzzo RG, Al-Saleem T, Greenberg RE, Polascik TJ, Babb JS, Grizzle WE, Cairns P. Promoter Hypermethylation Profile of Kidney Cancer Clinical Cancer Research. 10: 3972-3979. PMID 15217927 DOI: 10.1158/1078-0432.Ccr-04-0175  0.358
2004 Pandya AY, Talley LI, Frost AR, Fitzgerald TJ, Trivedi V, Chakravarthy M, Chhieng DC, Grizzle WE, Engler JA, Krontiras H, Bland KI, LoBuglio AF, Lobo-Ruppert SM, Ruppert JM. Nuclear localization of KLF4 is associated with an aggressive phenotype in early-stage breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 2709-19. PMID 15102675 DOI: 10.1158/1078-0432.Ccr-03-0484  0.331
2004 Manne U, Jhala NC, Jones J, Weiss HL, Chatla C, Meleth S, Suarez-Cuervo C, Grizzle WE. Prognostic significance of p27(kip-1) expression in colorectal adenocarcinomas is associated with tumor stage. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 1743-52. PMID 15014027 DOI: 10.1158/1078-0432.Ccr-03-0037  0.324
2004 Ponnazhagan S, Mahendra G, Kumar S, Shaw DR, Stockard CR, Grizzle WE, Meleth S. Adeno-associated virus 2-mediated antiangiogenic cancer gene therapy: long-term efficacy of a vector encoding angiostatin and endostatin over vectors encoding a single factor. Cancer Research. 64: 1781-7. PMID 14996740 DOI: 10.1158/0008-5472.Can-03-1786  0.344
2004 Bonner JA, Buchsbaum DJ, Rogers BE, Grizzle WE, Trummell HQ, Curiel DT, Fiveash JB, Ove R, Raisch KP. Adenoviral vector-mediated augmentation of epidermal growth factor receptor (EGFr) enhances the radiosensitization properties of anti-EGFr treatment in prostate cancer cells. International Journal of Radiation Oncology, Biology, Physics. 58: 950-8. PMID 14967455 DOI: 10.1016/J.Ijrobp.2003.09.095  0.322
2004 Straughn JM, Shaw DR, Guerrero A, Bhoola SM, Racelis A, Wang Z, Chiriva-Internati M, Grizzle WE, Alvarez RD, Lim SH, Strong TV. Expression of sperm protein 17 (Sp17) in ovarian cancer. International Journal of Cancer. 108: 805-11. PMID 14712480 DOI: 10.1002/Ijc.11617  0.348
2004 Alexander D, Chatla C, Funkhouser E, Jhala N, Grizzle W, Manne U. Racial differences in survival based on tumor differentiation and stage in patients who have undergone surgery for colon cancer Journal of Clinical Oncology. 22: 3609-3609. DOI: 10.1200/Jco.2004.22.90140.3609  0.317
2004 Everts M, Kim-Park SA, Le LP, Reynolds PN, Grizzle WE, Curiel DT. 21. Induction of CEA in Pulmonary Vasculature to Study Targeting Strategies for Cancer Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.05.044  0.332
2003 Weiss HL, Niwas S, Grizzle WE, Piyathilake C. Receiver operating characteristic (ROC) to determine cut-off points of biomarkers in lung cancer patients. Disease Markers. 19: 273-8. PMID 15258328 DOI: 10.1155/2004/856026  0.339
2003 Chhieng DC, Rodriguez-Burford C, Talley LI, Sviglin H, Stockard CR, Kleinberg MJ, Barnes MN, Partridge EE, Khazaeli MB, Grizzle WE. Expression of CEA, Tag-72, and Lewis-Y antigen in primary and metastatic lesions of ovarian carcinoma. Human Pathology. 34: 1016-21. PMID 14608535 DOI: 10.1053/S0046-8177(03)00355-1  0.31
2003 Rosenthal EL, Shreenivas S, Peters GE, Grizzle WE, Desmond R, Gladson CL. Expression of extracellular matrix metalloprotease inducer in laryngeal squamous cell carcinoma. The Laryngoscope. 113: 1406-10. PMID 12897567 DOI: 10.1097/00005537-200308000-00027  0.397
2003 Blume SW, Miller DM, Guarcello V, Shrestha K, Meng Z, Snyder RC, Grizzle WE, Ruppert JM, Gartland GL, Stockard CR, Jones DE, Emanuel PD. Inhibition of tumorigenicity by the 5'-untranslated RNA of the human c-myc P0 transcript. Experimental Cell Research. 288: 131-42. PMID 12878165 DOI: 10.1016/S0014-4827(03)00182-4  0.315
2003 Davila M, Frost AR, Grizzle WE, Chakrabarti R. LIM kinase 1 is essential for the invasive growth of prostate epithelial cells: implications in prostate cancer. The Journal of Biological Chemistry. 278: 36868-75. PMID 12821664 DOI: 10.1074/Jbc.M306196200  0.369
2003 Bell WC, Myers RB, Hosein TO, Oelschlager DK, Grizzle WE. The response of extracellular signal-regulated kinase (ERK) to androgen-induced proliferation in the androgen-sensitive prostate cancer cell line, LNCaP. Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission. 78: 11-6. PMID 12713136 DOI: 10.1080/10520290312120003  0.358
2003 Piyathilake CJ, Frost AR, Manne U, Weiss H, Heimburger DC, Grizzle WE. Nuclear accumulation of p53 is a potential marker for the development of squamous cell lung cancer in smokers. Chest. 123: 181-6. PMID 12527620 DOI: 10.1378/Chest.123.1.181  0.325
2002 Rodríguez-Burford C, Steele VE, Anderson AS, Stockard CR, Weiss HL, Eto I, Johanning GL, Grizzle WE, Grubbs CJ. Effects of body weight gain reduction resulting from chemopreventive agent treatment on mammary gland morphology. Nutrition and Cancer. 43: 67-75. PMID 12467137 DOI: 10.1207/S15327914Nc431_8  0.308
2002 MacLennan PA, Delzell E, Sathiakumar N, Myers SL, Cheng H, Grizzle W, Chen VW, Wu XC. Cancer incidence among triazine herbicide manufacturing workers. Journal of Occupational and Environmental Medicine / American College of Occupational and Environmental Medicine. 44: 1048-58. PMID 12448356 DOI: 10.1097/00043764-200211000-00011  0.325
2002 Buchsbaum DJ, Bonner JA, Grizzle WE, Stackhouse MA, Carpenter M, Hicklin DJ, Bohlen P, Raisch KP. Treatment of pancreatic cancer xenografts with Erbitux (IMC-C225) anti-EGFR antibody, gemcitabine, and radiation. International Journal of Radiation Oncology, Biology, Physics. 54: 1180-93. PMID 12419447 DOI: 10.1016/S0360-3016(02)03788-4  0.303
2002 Piyathilake CJ, Bell WC, Oelschlager DK, Heimburger DC, Grizzle WE. The pattern of expression of Mn and Cu-Zn superoxide dismutase varies among squamous cell cancers of the lung, larynx, and oral cavity. Head & Neck. 24: 859-67. PMID 12211050 DOI: 10.1002/Hed.10135  0.346
2002 Grizzle WE, Mountz JD, Yang PA, Xu X, Sun S, Van Zant GE, Williams RW, Hsu HC, Zhang HG. BXD recombinant inbred mice represent a novel T cell-mediated immune response tumor model. International Journal of Cancer. Journal International Du Cancer. 101: 270-9. PMID 12209979 DOI: 10.1002/Ijc.10606  0.335
2002 Barnes MN, Grizzle WE, Grubbs CJ, Partridge EE. Paradigms for primary prevention of ovarian carcinoma. Ca: a Cancer Journal For Clinicians. 52: 216-225. PMID 12139233 DOI: 10.3322/Canjclin.52.4.216  0.329
2002 Robles LD, Frost AR, Davila M, Hutson AD, Grizzle WE, Chakrabarti R. Down-regulation of Cdc6, a cell cycle regulatory gene, in prostate cancer. The Journal of Biological Chemistry. 277: 25431-8. PMID 12006585 DOI: 10.1074/Jbc.M201199200  0.353
2002 Grizzle WE, Manne U, Weiss HL, Jhala N, Talley L. Molecular staging of colorectal cancer in African-American and Caucasian patients using phenotypic expression of p53, Bcl-2, MUC-1 AND p27(kip-1). International Journal of Cancer. Journal International Du Cancer. 97: 403-9. PMID 11802199 DOI: 10.1002/Ijc.1617  0.317
2001 Meredith RF, Alvarez RD, Partridge EE, Khazaeli MB, Lin CY, Macey DJ, Austin JM, Kilgore LC, Grizzle WE, Schlom J, LoBuglio AF. Intraperitoneal radioimmunochemotherapy of ovarian cancer: a phase I study. Cancer Biotherapy & Radiopharmaceuticals. 16: 305-15. PMID 11603001 DOI: 10.1089/108497801753131381  0.318
2001 Rodrıguez-Burford C, Barnes MN, Berry W, Partridge EE, Grizzle WE. Immunohistochemical Expression of Molecular Markers in an Avian Model: A Potential Model for Preclinical Evaluation of Agents for Ovarian Cancer Chemoprevention Gynecologic Oncology. 81: 373-379. PMID 11371125 DOI: 10.1006/Gyno.2001.6191  0.346
2001 Beenken SW, Grizzle WE, Crowe DR, Conner MG, Weiss HL, Sellers MT, Krontiras H, Urist MM, Bland KI. Molecular biomarkers for breast cancer prognosis: coexpression of c-erbB-2 and p53. Annals of Surgery. 233: 630-8. PMID 11323501 DOI: 10.1097/00000658-200105000-00006  0.324
2001 Weiss HL, Urban DA, Grizzle WE, Cronin KA, Freedman LS, Kelloff GJ, Lieberman R. Bayesian monitoring of a phase 2 chemoprevention trial in high-risk cohorts for prostate cancer. Urology. 57: 220-3. PMID 11295632 DOI: 10.1016/S0090-4295(00)00979-1  0.308
2001 Yamamoto M, Alemany R, Adachi Y, Grizzle WE, Curiel DT. Characterization of the cyclooxygenase-2 promoter in an adenoviral vector and its application for the mitigation of toxicity in suicide gene therapy of gastrointestinal cancers. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 385-94. PMID 11273781 DOI: 10.1006/Mthe.2001.0275  0.313
2000 Piyathilake CJ, Frost AR, Manne U, Bell WC, Weiss H, Heimburger DC, Grizzle WE. The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung. Human Pathology. 31: 1068-73. PMID 11014573 DOI: 10.1053/Hupa.2000.9842  0.352
2000 Manne U, Weiss HL, Grizzle WE. Bcl-2 expression is associated with improved prognosis in patients with distal colorectal adenocarcinomas. International Journal of Cancer. 89: 423-30. PMID 11008204 DOI: 10.1002/1097-0215(20000920)89:5<423::Aid-Ijc5>3.0.Co;2-T  0.326
2000 Piyathilake CJ, Frost AR, Weiss H, Manne U, Heimburger DC, Grizzle WE. The expression of Ep-CAM (17-1A) in squamous cell cancers of the lung Human Pathology. 31: 482-487. PMID 10821496 DOI: 10.1053/Hp.2000.6711  0.37
2000 Ren S, Smith MJ, Louro ID, McKie-Bell P, Bani MR, Wagner M, Zochodne B, Redden DT, Grizzle WE, Wang Nd, Smith DI, Herbst RA, Bardenheuer W, Opalka B, Schütte J, et al. The p44S10 locus, encoding a subunit of the proteasome regulatory particle, is amplified during progression of cutaneous malignant melanoma. Oncogene. 19: 1419-27. PMID 10723133 DOI: 10.1038/Sj.Onc.1203462  0.352
1999 Saleh MN, Raisch KP, Stackhouse MA, Grizzle WE, Bonner JA, Mayo MS, Kim HG, Meredith RF, Wheeler RH, Buchsbaum DJ. Combined modality therapy of A431 human epidermoid cancer using anti-EGFr antibody C225 and radiation. Cancer Biotherapy & Radiopharmaceuticals. 14: 451-63. PMID 10850332 DOI: 10.1089/Cbr.1999.14.451  0.316
1999 Myers RB, Oelschlager D, Manne U, Coan PN, Weiss H, Grizzle WE. Androgenic regulation of growth factor and growth factor receptor expression in the CWR22 model of prostatic adenocarcinoma. International Journal of Cancer. 82: 424-9. PMID 10399960 DOI: 10.1002/(Sici)1097-0215(19990730)82:3<424::Aid-Ijc16>3.0.Co;2-B  0.313
1999 Krontiras H, Roye GD, Beenken SE, Myers RB, Mayo MS, Peters GE, Grizzle WE. Fatty acid synthase expression is increased in neoplastic lesions of the oral tongue. Head and Neck-Journal For the Sciences and Specialties of the Head and Neck. 21: 325-329. PMID 10376752 DOI: 10.1002/(Sici)1097-0347(199907)21:4<325::Aid-Hed6>3.0.Co;2-P  0.323
1999 Stackhouse MA, Buchsbaum DJ, Kancharla SR, Grizzle WE, Grimes C, Laffoon K, Pederson LC, Curiel DT. Specific membrane receptor gene expression targeted with radiolabeled peptide employing the erbB-2 and DF3 promoter elements in adenoviral vectors Cancer Gene Therapy. 6: 209-219. PMID 10359206 DOI: 10.1038/Sj.Cgt.7700049  0.355
1999 Urban D, Myers R, Manne U, Weiss H, Mohler J, Perkins D, Markiewicz M, Lieberman R, Kelloff G, Marshall M, Grizzle W. Evaluation of biomarker modulation by fenretinide in prostate cancer patients European Urology. 35: 429-438. PMID 10325501 DOI: 10.1159/000019875  0.361
1998 Fabian CJ, Kimler BF, Elledge RM, Grizzle WE, Beenken SW, Ward JH. Models for early chemoprevention trials in breast cancer Hematology-Oncology Clinics of North America. 12: 993-1017. PMID 9888018 DOI: 10.1016/S0889-8588(05)70038-1  0.311
1998 Stackhouse MA, Buchsbaum DJ, Grizzle WE, Bright SJ, Olsen CC, Kancharla S, Mayo MS, Curiel DT. Radiosensitization mediated by a transfected anti-erbB-2 single-chain antibody in vitro and in vivo. International Journal of Radiation Oncology, Biology, Physics. 42: 817-22. PMID 9845103 DOI: 10.1016/S0360-3016(98)00330-7  0.385
1998 Saleh MN, Tilden AB, Meredith RF, Lobuglio AF, Grizzle WE. Chimeric antibodies with specificity for tumor antigens: demonstration of in situ localization to tumors after antibody therapy. Biotechnic & Histochemistry. 73: 186-197. PMID 9735877 DOI: 10.3109/10520299809141109  0.318
1997 Manne U, Myers RB, Moron C, Poczatek RB, Dillard S, Weiss H, Brown D, Srivastava S, Grizzle WE. Prognostic significance of Bcl-2 expression and p53 nuclear accumulation in colorectal adenocarcinoma. International Journal of Cancer. 74: 346-58. PMID 9221816 DOI: 10.1002/(Sici)1097-0215(19970620)74:3<346::Aid-Ijc19>3.0.Co;2-9  0.318
1997 Myers RB, Grizzle WE. Changes in biomarker expression in the development of prostatic adenocarcinoma. Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission. 72: 86-95. PMID 9152521 DOI: 10.3109/10520299709082217  0.353
1997 Manne U, Myers RB, Srivastava S, Grizzle WE. Re: loss of tumor marker-immunostaining intensity on stored paraffin slides of breast cancer. Journal of the National Cancer Institute. 89: 585-6. PMID 9106651 DOI: 10.1093/Jnci/89.8.585  0.338
1997 Alvarez RD, Partridge EE, Khazaeli MB, Plott G, Austin M, Kilgore L, Russell CD, Liu T, Grizzle WE, Schlom J, LoBuglio AF, Meredith RF. Intraperitoneal radioimmunotherapy of ovarian cancer with 177Lu- CC49: A phase I/II study Gynecologic Oncology. 65: 94-101. PMID 9103398 DOI: 10.1006/Gyno.1996.4577  0.306
1996 Myers RB, Oelschlager DK, Hockett RD, Rogers MD, Conway-Myers BA, Grizzle WE. The effects of dihydrotestosterone on the expression of p185(erbB-2) and c-erbB-2 mRNA in the prostatic cell line LNCaP. The Journal of Steroid Biochemistry and Molecular Biology. 59: 441-7. PMID 9010349 DOI: 10.1016/S0960-0760(96)00143-4  0.311
1996 Myers RB, Brown D, Oelschlager DK, Waterbor JW, Marshall ME, Srivastava S, Stockard CR, Urban DA, Grizzle WE. Elevated serum levels of p105(erbB-2) in patients with advanced-stage prostatic adenocarcinoma. International Journal of Cancer. Journal International Du Cancer. 69: 398-402. PMID 8900374 DOI: 10.1002/(Sici)1097-0215(19961021)69:5<398::Aid-Ijc8>3.0.Co;2-0  0.333
1996 Arnold MM, Srivastava S, Fredenburgh J, Stockard CR, Myers RB, Grizzle WE. Effects of fixation and tissue processing on immunohistochemical demonstration of specific antigens. Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission. 71: 224-30. PMID 8896794 DOI: 10.3109/10520299609117164  0.34
1996 Myers RB, Srivastava S, Oelschlager DK, Brown D, Grizzle WE. Expression of nm23-H1 in prostatic intraepithelial neoplasia and adenocarcinoma. Human Pathology. 27: 1021-4. PMID 8892585 DOI: 10.1016/S0046-8177(96)90278-6  0.303
1996 Grizzle WE. Silver Staining Methods to Identify Cells of the Dispersed Neuroendocrine System Journal of Histotechnology. 19: 225-234. DOI: 10.1179/His.1996.19.3.225  0.329
1995 Grizzle WE, Myers RB, Oelschlager DK. Prognostic Biomarkers in Breast Cancer: Factors Affecting Immunohistochemical Evaluation Breast Journal. 1: 243-250. DOI: 10.1111/J.1524-4741.1995.Tb00246.X  0.372
1995 Myers RB, Srivastava S, Grizzle WE. Lewis Y Antigen as Detected by the Monoclonal Antibody BR96 is Expressed Strongly in Prostatic Adenocarcinoma Journal of Urology. 153: 1572-1574. DOI: 10.1016/S0022-5347(01)67464-0  0.341
1994 Myers RB, Meredith RF, Schlom J, LoBuglio AF, Bueschen AJ, Wheeler RH, Stockard CR, Grizzle WE. Tumor Associated Glycoprotein-72 is Highly Expressed in Prostatic Adenocarcinomas The Journal of Urology. 152: 243-246. PMID 8201675 DOI: 10.1016/S0022-5347(17)32870-7  0.333
1994 Myers RB, Oelschlager D, Srivastava S, Grizzle WE. Accumulation of the p53 protein occurs more frequently in metastatic than in localized prostatic adenocarcinomas. The Prostate. 25: 243-8. PMID 7971515 DOI: 10.1002/Pros.2990250504  0.302
1994 Kakar SS, Grizzle WE, Neill JD. The nucleotide sequences of human GnRH receptors in breast and ovarian tumors are identical with that found in pituitary Molecular and Cellular Endocrinology. 106: 145-149. PMID 7534732 DOI: 10.1016/0303-7207(94)90196-1  0.348
1993 Meredith RF, Khazaeli MB, Grizzle WE, Orr RA, Plott G, Urist MM, Liu T, Russell CD, Wheeler RH, Schlom J, LoBuglio AF. Direct localization comparison of murine and chimeric B72.3 antibodies in patients with colon cancer Human Antibodies. 4: 190-197. PMID 8257773 DOI: 10.3233/Hab-1993-4406  0.304
1990 Bookstein R, Rio P, Madreperla SA, Hong F, Allred C, Grizzle WE, Lee W. Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 87: 7762-7766. PMID 2217208 DOI: 10.1073/Pnas.87.19.7762  0.344
1987 Clausen KP, Grizzle WE, Livolsi VA, Newton WE. Availability of human tissues for research in cancer. Science. 237: 10-11. DOI: 10.1126/Science.237.4810.10-C  0.331
1984 Herrera GA, Moraes HPD, Grizzle WE, Han SG. Malignant small bowel neoplasm of enteric plexus derivation (plexosarcoma). Light and electron microscopic study confirming the origin of the neoplasm. Digestive Diseases and Sciences. 29: 275-284. PMID 6321118 DOI: 10.1007/Bf01296263  0.307
1982 Phillips JG, Orr JW, Grizzle W, Hatch KD, Shingleton HM. An extra-adrenal pheochromocytoma mimicking lymph node metastasis from a cervical cancer Gynecologic Oncology. 13: 416-422. PMID 7095580 DOI: 10.1016/0090-8258(82)90081-6  0.309
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