| Year |
Citation |
Score |
| 2018 |
Dyer A, Schoeps B, Frost S, Jakeman PG, Scott EM, Freedman J, Seymour LW. Antagonism of glycolysis and reductive carboxylation of glutamine potentiates activity of oncolytic adenoviruses in cancer cells. Cancer Research. PMID 30487139 DOI: 10.1158/0008-5472.Can-18-1326 |
0.32 |
|
| 2018 |
Freedman JD, Duffy MR, Lei-Rossmann J, Muntzer A, Scott EM, Hagel J, Campo L, Bryant RJ, Verrill C, Lambert A, Miller P, Champion BR, Seymour LW, Fisher KD. An Oncolytic Virus Expressing a T-cell Engager Simultaneously Targets Cancer and Immunosuppressive Stromal Cells. Cancer Research. PMID 30449733 DOI: 10.1158/0008-5472.Can-18-1750 |
0.333 |
|
| 2017 |
Scott EM, Duffy MR, Freedman JD, Fisher KD, Seymour LW. Solid Tumor Immunotherapy with T Cell Engager-Armed Oncolytic Viruses. Macromolecular Bioscience. PMID 28902983 DOI: 10.1002/Mabi.201700187 |
0.322 |
|
| 2017 |
O'Cathail SM, Pokrovska TD, Maughan TS, Fisher KD, Seymour LW, Hawkins MA. Combining Oncolytic Adenovirus with Radiation-A Paradigm for the Future of Radiosensitization. Frontiers in Oncology. 7: 153. PMID 28791251 DOI: 10.3389/Fonc.2017.00153 |
0.341 |
|
| 2017 |
Freedman JD, Hagel J, Scott EM, Psallidas I, Gupta A, Spiers L, Miller P, Kanellakis N, Ashfield R, Fisher KD, Duffy MR, Seymour LW. Oncolytic adenovirus expressing bispecific antibody targets T-cell cytotoxicity in cancer biopsies. Embo Molecular Medicine. PMID 28634161 DOI: 10.15252/Emmm.201707567 |
0.325 |
|
| 2017 |
Dyer A, Di Y, Calderon H, Illingworth S, Kueberuwa G, Tedcastle A, Jakeman P, Chia SL, Brown A, Silva MA, Barlow D, Beadle J, Hermiston T, Ferguson DJ, Champion B, ... ... Seymour LW, et al. Oncolytic Group B Adenovirus Enadenotucirev Mediates Non-apoptotic Cell Death with Membrane Disruption and Release of Inflammatory Mediators. Molecular Therapy Oncolytics. 4: 18-30. PMID 28345021 DOI: 10.1016/J.Omto.2016.11.003 |
0.31 |
|
| 2017 |
Chia SL, Lei J, Ferguson DJ, Dyer A, Fisher KD, Seymour LW. Group B adenovirus enadenotucirev infects polarised colorectal cancer cells efficiently from the basolateral surface expected to be encountered during intravenous delivery to treat disseminated cancer. Virology. 505: 162-171. PMID 28260622 DOI: 10.1016/J.Virol.2017.02.011 |
0.305 |
|
| 2016 |
Seymour LW, Fisher KD. Oncolytic viruses: finally delivering. British Journal of Cancer. PMID 26766734 DOI: 10.1038/Bjc.2015.481 |
0.338 |
|
| 2015 |
Tedcastle A, Illingworth S, Brown A, Seymour LW, Fisher KD. Actin resistant DNAse I expression from oncolytic adenovirus Enadenotucirev enhances its intratumoural spread and reduces tumour growth. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26708004 DOI: 10.1038/Mt.2015.233 |
0.321 |
|
| 2015 |
Lynn GM, Laga R, Darrah PA, Ishizuka AS, Balaci AJ, Dulcey AE, Pechar M, Pola R, Gerner MY, Yamamoto A, Buechler CR, Quinn KM, Smelkinson MG, Vanek O, Cawood R, ... ... Seymour LW, et al. In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity. Nature Biotechnology. 33: 1201-10. PMID 26501954 DOI: 10.1038/Nbt.3371 |
0.305 |
|
| 2015 |
Kostka L, Šubr V, Laga R, Chytil P, Ulbrich K, Seymour LW, Etrych T. Nanotherapeutics shielded with a pH responsive polymeric layer. Physiological Research / Academia Scientiarum Bohemoslovaca. 64: S29-40. PMID 26447593 DOI: 10.33549/Physiolres.933139 |
0.382 |
|
| 2015 |
Mo S, Carlisle R, Laga R, Myers R, Graham S, Cawood R, Ulbrich K, Seymour L, Coussios CC. Increasing the density of nanomedicines improves their ultrasound-mediated delivery to tumours. Journal of Controlled Release : Official Journal of the Controlled Release Society. 210: 10-8. PMID 25975831 DOI: 10.1016/J.Jconrel.2015.05.265 |
0.34 |
|
| 2015 |
Jakeman PG, Hills TE, Tedcastle AB, Di Y, Fisher KD, Seymour LW. Improved in vitro human tumor models for cancer gene therapy. Human Gene Therapy. 26: 249-56. PMID 25808057 DOI: 10.1089/Hum.2015.028 |
0.312 |
|
| 2014 |
Di Y, Seymour L, Fisher K. Activity of a group B oncolytic adenovirus (ColoAd1) in whole human blood. Gene Therapy. 21: 440-3. PMID 24553347 DOI: 10.1038/Gt.2014.2 |
0.321 |
|
| 2013 |
Bazan-Peregrino M, Sainson RC, Carlisle RC, Thoma C, Waters RA, Arvanitis C, Harris AL, Hernandez-Alcoceba R, Seymour LW. Combining virotherapy and angiotherapy for the treatment of breast cancer. Cancer Gene Therapy. 20: 461-8. PMID 23846253 DOI: 10.1038/Cgt.2013.41 |
0.302 |
|
| 2008 |
Bazan-Peregrino M, Carlisle RC, Purdie L, Seymour LW. Factors influencing retention of adenovirus within tumours following direct intratumoural injection. Gene Therapy. 15: 688-94. PMID 18288207 DOI: 10.1038/Gt.2008.2 |
0.303 |
|
| 2008 |
Morrison J, Briggs SS, Green N, Fisher K, Subr V, Ulbrich K, Kehoe S, Seymour LW. Virotherapy of ovarian cancer with polymer-cloaked adenovirus retargeted to the epidermal growth factor receptor. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 244-51. PMID 18071336 DOI: 10.1038/Sj.Mt.6300363 |
0.365 |
|
| 2007 |
Stevenson M, Hale AB, Hale SJ, Green NK, Black G, Fisher KD, Ulbrich K, Fabra A, Seymour LW. Incorporation of a laminin-derived peptide (SIKVAV) on polymer-modified adenovirus permits tumor-specific targeting via alpha6-integrins. Cancer Gene Therapy. 14: 335-45. PMID 17235355 DOI: 10.1038/Sj.Cgt.7701022 |
0.391 |
|
| 2007 |
Bazan-Peregrino M, Seymour LW, Harris AL. Gene therapy targeting to tumor endothelium. Cancer Gene Therapy. 14: 117-27. PMID 17096029 DOI: 10.1038/Sj.Cgt.7701001 |
0.33 |
|
| 2005 |
Parker AL, Fisher KD, Oupicky D, Read ML, Nicklin SA, Baker AH, Seymour LW. Enhanced gene transfer activity of peptide-targeted gene-delivery vectors. Journal of Drug Targeting. 13: 39-51. PMID 15848953 DOI: 10.1080/10611860400020449 |
0.302 |
|
| 2004 |
Howard KA, Li XW, Somavarapu S, Singh J, Green N, Atuah KN, Ozsoy Y, Seymour LW, Alpar HO. Formulation of a microparticle carrier for oral polyplex-based DNA vaccines. Biochimica Et Biophysica Acta. 1674: 149-57. PMID 15374619 DOI: 10.1016/J.Bbagen.2004.06.009 |
0.382 |
|
| 2004 |
Barrett LB, Berry M, Ying WB, Hodgkin MN, Seymour LW, Gonzalez AM, Read ML, Baird A, Logan A. CTb targeted non-viral cDNA delivery enhances transgene expression in neurons. The Journal of Gene Medicine. 6: 429-38. PMID 15079817 DOI: 10.1002/Jgm.524 |
0.342 |
|
| 2003 |
Read ML, Bremner KH, Oupický D, Green NK, Searle PF, Seymour LW. Vectors based on reducible polycations facilitate intracellular release of nucleic acids. The Journal of Gene Medicine. 5: 232-45. PMID 12666189 DOI: 10.1002/Jgm.331 |
0.323 |
|
| 2002 |
Ward CM, Pechar M, Oupicky D, Ulbrich K, Seymour LW. Modification of pLL/DNA complexes with a multivalent hydrophilic polymer permits folate-mediated targeting in vitro and prolonged plasma circulation in vivo. The Journal of Gene Medicine. 4: 536-47. PMID 12221647 DOI: 10.1002/Jgm.296 |
0.409 |
|
| 2002 |
Oupický D, Ogris M, Seymour LW. Development of long-circulating polyelectrolyte complexes for systemic delivery of genes. Journal of Drug Targeting. 10: 93-8. PMID 12074545 DOI: 10.1080/10611860290016685 |
0.399 |
|
| 2002 |
Maruta F, Parker AL, Fisher KD, Hallissey MT, Ismail T, Rowlands DC, Chandler LA, Kerr DJ, Seymour LW. Identification of FGF receptor-binding peptides for cancer gene therapy. Cancer Gene Therapy. 9: 543-52. PMID 12032665 DOI: 10.1038/Sj.Cgt.7700470 |
0.328 |
|
| 2002 |
Reschel T, Konák C, Oupický D, Seymour LW, Ulbrich K. Physical properties and in vitro transfection efficiency of gene delivery vectors based on complexes of DNA with synthetic polycations. Journal of Controlled Release : Official Journal of the Controlled Release Society. 81: 201-17. PMID 11992692 DOI: 10.1016/S0168-3659(02)00045-7 |
0.365 |
|
| 2002 |
Oupicky D, Ogris M, Howard KA, Dash PR, Ulbrich K, Seymour LW. Importance of lateral and steric stabilization of polyelectrolyte gene delivery vectors for extended systemic circulation. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 463-72. PMID 11945074 DOI: 10.1006/Mthe.2002.0568 |
0.371 |
|
| 2002 |
Seymour LW, Ferry DR, Anderson D, Hesslewood S, Julyan PJ, Poyner R, Doran J, Young AM, Burtles S, Kerr DJ. Hepatic drug targeting: phase I evaluation of polymer-bound doxorubicin. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 20: 1668-76. PMID 11896118 DOI: 10.1200/Jco.20.6.1668 |
0.362 |
|
| 2002 |
Parker AL, Oupicky D, Dash PR, Seymour LW. Methodologies for monitoring nanoparticle formation by self-assembly of DNA with poly(l-lysine). Analytical Biochemistry. 302: 75-80. PMID 11846378 DOI: 10.1006/Abio.2001.5507 |
0.336 |
|
| 2002 |
Oupický D, Parker AL, Seymour LW. Laterally stabilized complexes of DNA with linear reducible polycations: strategy for triggered intracellular activation of DNA delivery vectors. Journal of the American Chemical Society. 124: 8-9. PMID 11772047 DOI: 10.1021/Ja016440N |
0.401 |
|
| 2001 |
Carlisle RC, Bettinger T, Ogris M, Hale S, Mautner V, Seymour LW. Adenovirus hexon protein enhances nuclear delivery and increases transgene expression of polyethylenimine/plasmid DNA vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 4: 473-83. PMID 11708884 DOI: 10.1006/Mthe.2001.0472 |
0.349 |
|
| 2001 |
Ogris M, Carlisle RC, Bettinger T, Seymour LW. Melittin enables efficient vesicular escape and enhanced nuclear access of nonviral gene delivery vectors. The Journal of Biological Chemistry. 276: 47550-5. PMID 11600500 DOI: 10.1074/Jbc.M108331200 |
0.387 |
|
| 2001 |
Bettinger T, Carlisle RC, Read ML, Ogris M, Seymour LW. Peptide-mediated RNA delivery: a novel approach for enhanced transfection of primary and post-mitotic cells. Nucleic Acids Research. 29: 3882-91. PMID 11557821 DOI: 10.1093/Nar/29.18.3882 |
0.318 |
|
| 2001 |
Oupický D, Carlisle RC, Seymour LW. Triggered intracellular activation of disulfide crosslinked polyelectrolyte gene delivery complexes with extended systemic circulation in vivo. Gene Therapy. 8: 713-24. PMID 11406766 DOI: 10.1038/Sj.Gt.3301446 |
0.388 |
|
| 2001 |
Atkinson SF, Bettinger T, Seymour LW, Behr JP, Ward CM. Conjugation of folate via gelonin carbohydrate residues retains ribosomal-inactivating properties of the toxin and permits targeting to folate receptor positive cells. The Journal of Biological Chemistry. 276: 27930-5. PMID 11359781 DOI: 10.1074/Jbc.M102825200 |
0.345 |
|
| 2001 |
Fisher KD, Stallwood Y, Green NK, Ulbrich K, Mautner V, Seymour LW. Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies. Gene Therapy. 8: 341-8. PMID 11313809 DOI: 10.1038/Sj.Gt.3301389 |
0.392 |
|
| 2001 |
Ward CM, Read ML, Seymour LW. Systemic circulation of poly(L-lysine)/DNA vectors is influenced by polycation molecular weight and type of DNA: differential circulation in mice and rats and the implications for human gene therapy. Blood. 97: 2221-9. PMID 11290582 DOI: 10.1182/Blood.V97.8.2221 |
0.367 |
|
| 2000 |
Fisher KD, Ulbrich K, Subr V, Ward CM, Mautner V, Blakey D, Seymour LW. A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression. Gene Therapy. 7: 1337-43. PMID 10918506 DOI: 10.1038/Sj.Gt.3301230 |
0.421 |
|
| 2000 |
Howard KA, Dash PR, Read ML, Ward K, Tomkins LM, Nazarova O, Ulbrich K, Seymour LW. Influence of hydrophilicity of cationic polymers on the biophysical properties of polyelectrolyte complexes formed by self-assembly with DNA. Biochimica Et Biophysica Acta. 1475: 245-55. PMID 10913823 DOI: 10.1016/S0304-4165(00)00076-3 |
0.389 |
|
| 2000 |
Ward CM, Acheson N, Seymour LW. Folic acid targeting of protein conjugates into ascites tumour cells from ovarian cancer patients. Journal of Drug Targeting. 8: 119-23. PMID 10852343 DOI: 10.3109/10611860008996857 |
0.336 |
|
| 2000 |
Read ML, Dash PR, Clark A, Howard KA, Oupicky D, Toncheva V, Alpar HO, Schacht EH, Ulbrich K, Seymour LW. Physicochemical and biological characterisation of an antisense oligonucleotide targeted against the bcl-2 mRNA complexed with cationic-hydrophilic copolymers. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 10: 169-77. PMID 10767594 DOI: 10.1016/S0928-0987(00)00069-5 |
0.398 |
|
| 2000 |
Dekie L, Toncheva V, Dubruel P, Schacht EH, Barrett L, Seymour LW. Poly-L-glutamic acid derivatives as vectors for gene therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 65: 187-202. PMID 10699280 DOI: 10.1016/S0168-3659(99)00235-7 |
0.386 |
|
| 2000 |
Oupický D, Konák C, Ulbrich K, Wolfert MA, Seymour LW. DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers. Journal of Controlled Release : Official Journal of the Controlled Release Society. 65: 149-71. PMID 10699278 DOI: 10.1016/S0168-3659(99)00249-7 |
0.362 |
|
| 2000 |
Dash PR, Read ML, Fisher KD, Howard KA, Wolfert M, Oupicky D, Subr V, Strohalm J, Ulbrich K, Seymour LW. Decreased binding to proteins and cells of polymeric gene delivery vectors surface modified with a multivalent hydrophilic polymer and retargeting through attachment of transferrin. The Journal of Biological Chemistry. 275: 3793-802. PMID 10660529 DOI: 10.1074/Jbc.275.6.3793 |
0.411 |
|
| 1999 |
Wolfert MA, Dash PR, Nazarova O, Oupicky D, Seymour LW, Smart S, Strohalm J, Ulbrich K. Polyelectrolyte vectors for gene delivery: influence of cationic polymer on biophysical properties of complexes formed with DNA. Bioconjugate Chemistry. 10: 993-1004. PMID 10563768 DOI: 10.1021/Bc990025R |
0.37 |
|
| 1999 |
Read ML, Etrych T, Ulbrich K, Seymour LW. Characterisation of the binding interaction between poly(L-lysine) and DNA using the fluorescamine assay in the preparation of non-viral gene delivery vectors. Febs Letters. 461: 96-100. PMID 10561503 DOI: 10.1016/S0014-5793(99)01435-0 |
0.409 |
|
| 1999 |
Oupický D, Konák C, Dash PR, Seymour LW, Ulbrich K. Effect of albumin and polyanion on the structure of DNA complexes with polycation containing hydrophilic nonionic block. Bioconjugate Chemistry. 10: 764-72. PMID 10502341 DOI: 10.1021/Bc990007+ |
0.357 |
|
| 1999 |
Dash PR, Read ML, Barrett LB, Wolfert MA, Seymour LW. Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery. Gene Therapy. 6: 643-50. PMID 10476224 DOI: 10.1038/Sj.Gt.3300843 |
0.364 |
|
| 1999 |
Soyez H, Seymour LW, Schacht E. Macromolecular derivatives of N,N-di-(2-chloroethyl)-4-phenylene diamine mustard. 2. In vitro cytotoxicity and in vivo anticancer efficacy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 57: 187-96. PMID 9971901 DOI: 10.1016/S0168-3659(98)00117-5 |
0.389 |
|
| 1999 |
Julyan PJ, Seymour LW, Ferry DR, Daryani S, Boivin CM, Doran J, David M, Anderson D, Christodoulou C, Young AM, Hesslewood S, Kerr DJ. Preliminary clinical study of the distribution of HPMA copolymers bearing doxorubicin and galactosamine. Journal of Controlled Release : Official Journal of the Controlled Release Society. 57: 281-90. PMID 9895415 DOI: 10.1016/S0168-3659(98)00124-2 |
0.336 |
|
| 1999 |
Carlisle RC, Read ML, Wolfert MA, Seymour LW. Self-assembling poly(L-lysine)/DNA complexes capable of integrin- mediated cellular uptake and gene expression Colloids and Surfaces B: Biointerfaces. 16: 261-272. DOI: 10.1016/S0927-7765(99)00077-6 |
0.388 |
|
| 1999 |
Ward CM, Fisher KD, Seymour LW. Turbidometric analysis of polyelectrolyte complexes formed between poly(L-lysine) and DNA Colloids and Surfaces B: Biointerfaces. 16: 253-260. DOI: 10.1016/S0927-7765(99)00076-4 |
0.369 |
|
| 1998 |
Baban DF, Seymour LW. Control of tumour vascular permeability. Advanced Drug Delivery Reviews. 34: 109-119. PMID 10837673 DOI: 10.1016/S0169-409X(98)00003-9 |
0.332 |
|
| 1998 |
Wolfert MA, Seymour LW. Chloroquine and amphipathic peptide helices show synergistic transfection in vitro. Gene Therapy. 5: 409-14. PMID 9614562 DOI: 10.1038/Sj.Gt.3300606 |
0.37 |
|
| 1998 |
Toncheva V, Wolfert MA, Dash PR, Oupicky D, Ulbrich K, Seymour LW, Schacht EH. Novel vectors for gene delivery formed by self-assembly of DNA with poly(L-lysine) grafted with hydrophilic polymers. Biochimica Et Biophysica Acta. 1380: 354-68. PMID 9555094 DOI: 10.1016/S0304-4165(98)00004-X |
0.401 |
|
| 1998 |
Hart SL, Arancibia-Cárcamo CV, Wolfert MA, Mailhos C, O'Reilly NJ, Ali RR, Coutelle C, George AJ, Harbottle RP, Knight AM, Larkin DF, Levinsky RJ, Seymour LW, Thrasher AJ, Kinnon C. Lipid-mediated enhancement of transfection by a nonviral integrin-targeting vector. Human Gene Therapy. 9: 575-85. PMID 9525318 DOI: 10.1089/Hum.1998.9.4-575 |
0.361 |
|
| 1998 |
Konak C, Mrkvickova L, Nazarova O, Ulbrich K, Seymour LW. Formation of DNA complexes with diblock copolymers of poly(N-(2-hydroxypropyl)methacrylamide) and polycations Supramolecular Science. 5: 67-74. DOI: 10.1016/S0968-5677(97)00069-2 |
0.311 |
|
| 1997 |
Nichifor M, Schacht EH, Seymour LW, Anderson D, Shoaibi M. Cytotoxicity and anticancer activity of macromolecular prodrugs of 5-fluorouracil Journal of Bioactive and Compatible Polymers. 12: 265-281. DOI: 10.1177/088391159701200401 |
0.376 |
|
| 1997 |
Nichifor M, Schacht EH, Seymour LW. Polymeric prodrugs of 5-fluorouracil Journal of Controlled Release. 48: 165-178. DOI: 10.1016/S0168-3659(97)00048-5 |
0.361 |
|
| 1997 |
Dash PR, Toncheva V, Schacht E, Seymour LW. Synthetic polymers for vectorial delivery of DNA: Characterisation of polymer-DNA complexes by photon correlation spectroscopy and stability to nuclease degradation and disruption by polyanions in vitro Journal of Controlled Release. 48: 269-276. DOI: 10.1016/S0168-3659(97)00043-6 |
0.389 |
|
| 1997 |
Lemmouchi Y, Schacht E, Dejardin S, Vandorpe J, Seymour L. Biodegradable polyphosphazenes for drug delivery Macromolecular Symposia. 123: 103-112. DOI: 10.1002/Masy.19971230111 |
0.333 |
|
| 1996 |
Nichifor M, Schacht EH, Seymour LW. Macromolecular prodrugs of 5-fluorouracil. 2: Enzymatic degradation Journal of Controlled Release. 39: 79-92. DOI: 10.1016/0168-3659(95)00141-7 |
0.342 |
|
| 1996 |
Steyger PS, Baban DF, Brereton M, Ulbrich K, Seymour LW. Intratumoural Journal of Controlled Release. 39: 35-46. DOI: 10.1016/0168-3659(95)00131-X |
0.595 |
|
| 1996 |
Soyez H, Schacht E, De Marre A, Seymour LW. Polymeric prodrugs of mitomycin C Macromolecular Symposia. 103: 163-176. DOI: 10.1002/Masy.19961030117 |
0.344 |
|
| 1995 |
Seymour LW, Miyamoto Y, Maeda H, Brereton M, Strohalm J, Ulbrich K, Duncan R. Influence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier. European Journal of Cancer (Oxford, England : 1990). 31: 766-70. PMID 7640051 DOI: 10.1016/0959-8049(94)00514-6 |
0.304 |
|
| 1995 |
De Marre A, Soyez H, Schacht E, Shoaibi MA, Seymour LW, Rihova B. Synthesis and evaluation of macromolecular prodrugs of mitomycin C Journal of Controlled Release. 36: 87-97. DOI: 10.1016/0168-3659(95)00058-G |
0.345 |
|
| 1995 |
Cremers HFM, Lens JP, Seymour LW, Feijen J. Biodegradable ion-exchange microspheres based on modified polylysines Journal of Controlled Release. 36: 167-179. DOI: 10.1016/0168-3659(95)00048-D |
0.358 |
|
| 1994 |
Seymour LW, Ulbrich K, Steyger PS, Brereton M, Subr V, Strohalm J, Duncan R. Tumour tropism and anti-cancer efficacy of polymer-based doxorubicin prodrugs in the treatment of subcutaneous murine B16F10 melanoma. British Journal of Cancer. 70: 636-41. PMID 7917909 DOI: 10.1038/Bjc.1994.363 |
0.596 |
|
| 1994 |
Marre AD, Seymour LW, Schacht E. Evaluation of the hydrolytic and enzymatic stability of macromolecular Mitomycin C derivatives Journal of Controlled Release. 31: 89-97. DOI: 10.1016/0168-3659(94)90254-2 |
0.313 |
|
| 1993 |
Ulbrich K, Šubr V, Seymour LW, Duncan R. Novel biodegradable hydrogels prepared using the divinylic crosslinking agent N,O-dimethacryloylhydroxylamine. 1. Synthesis and characterisation of rates of gel degradation, and rate of release of model drugs, in vitro and in vivo Journal of Controlled Release. 24: 181-190. DOI: 10.1016/0168-3659(93)90177-7 |
0.33 |
|
| 1992 |
Duncan R, Seymour LW, O'Hare KB, Flanagan PA, Wedge S, Hume IC, Ulbrich K, Strohalm J, Subr V, Spreafico F, Grandi M, Ripamonti M, Farao M, Suarato A. Preclinical evaluation of polymer-bound doxorubicin Journal of Controlled Release. 19: 331-346. DOI: 10.1016/0168-3659(92)90088-9 |
0.382 |
|
| 1991 |
Yeung TK, Hopewell JW, Simmonds RH, Seymour LW, Duncan R, Bellini O, Grandi M, Spreafico F, Strohalm J, Ulbrich K. Reduced cardiotoxicity of doxorubicin given in the form of N-(2-hydroxypropyl)methacrylamide conjugates: and experimental study in the rat. Cancer Chemotherapy and Pharmacology. 29: 105-11. PMID 1760851 DOI: 10.1007/Bf00687318 |
0.345 |
|
| 1991 |
Seymour LW, Ulbrich K, Wedge SR, Hume IC, Strohalm J, Duncan R. N-(2-hydroxypropyl)methacrylamide copolymers targeted to the hepatocyte galactose-receptor: pharmacokinetics in DBA2 mice. British Journal of Cancer. 63: 859-66. PMID 1648946 DOI: 10.1038/Bjc.1991.190 |
0.357 |
|
| 1988 |
Duncan R, Seymour LW, Ulbrich K, Kopecek J. Soluble synthetic polymers for targeting and controlled release of anticancer agents, particularly anthracycline antibiotics Journal of Bioactive and Compatible Polymers. 3: 4-15. DOI: 10.1177/088391158800300102 |
0.328 |
|
| 1987 |
Seymour LW, Duncan R, Strohalm J, Kopecek J. Effect of molecular weight (Mw) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats. Journal of Biomedical Materials Research. 21: 1341-58. PMID 3680316 DOI: 10.1002/Jbm.820211106 |
0.313 |
|
| 1987 |
Seymour LW, Duncan R, Kopecková P, Kopecek J. Daunomycin- and adriamycin-N-(2-hydroxypropyl)methacrylamide copolymer conjugates; toxicity reduction by improved drug-delivery. Cancer Treatment Reviews. 14: 319-27. PMID 3326668 DOI: 10.1016/0305-7372(87)90024-7 |
0.318 |
|
| 1987 |
Seymour LW, Duncan R, Kopeckova P, Kopecek J. Potential of sugar residues attached to N-(2-hydroxypropyl)methacrylamide copolymers as targeting groups for the selective delivery of drugs Journal of Bioactive and Compatible Polymers. 2: 97-119. DOI: 10.1177/088391158700200201 |
0.366 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 1999 |
Barrett LB, Seymour LW, Fisher KD, Ying W, Dash PR, Berry M, Logan A, Gonzalez AM, Baird A. Gene delivery to the CNS using non-viral vectors Biochemical Society Transactions. 27. DOI: 10.1042/Bst027A138C |
0.3 |
|
| 2008 |
Stevenson M, Ramos-Perez V, Singh S, Soliman M, Preece JA, Briggs SS, Read ML, Seymour LW. Delivery of siRNA mediated by histidine-containing reducible polycations. Journal of Controlled Release : Official Journal of the Controlled Release Society. 130: 46-56. PMID 18571758 DOI: 10.1016/j.jconrel.2008.05.014 |
0.299 |
|
| 2006 |
Carlisle RC, Briggs SS, Hale AB, Green NK, Fisher KD, Etrych T, Ulbrich K, Mautner V, Seymour LW. Use of synthetic vectors for neutralising antibody resistant delivery of replicating adenovirus DNA. Gene Therapy. 13: 1579-86. PMID 16810196 DOI: 10.1038/Sj.Gt.3302814 |
0.298 |
|
| 2003 |
Maruta F, Parker AL, Fisher KD, Murray PG, Kerr DJ, Seymour LW. Use of a phage display library to identify oligopeptides binding to the lumenal surface of polarized endothelium by ex vivo perfusion of human umbilical veins. Journal of Drug Targeting. 11: 53-9. PMID 12852441 DOI: 10.1080/1061186031000086063 |
0.298 |
|
| 1998 |
Seymour LW, Olliff SP, Poole CJ, De Takats PG, Orme R, Ferry DR, Maeda H, Konno T, Kerr DJ. A novel dosage approach for evaluation of SMANCS [poly-(styrene-co-maleyl-half-n-butylate) - neocarzinostatin] in the treatment of primary hepatocellular carcinoma. International Journal of Oncology. 12: 1217-23. PMID 9592177 DOI: 10.3892/Ijo.12.6.1217 |
0.292 |
|
| 2012 |
Schacht E, Vandorpe J, Dejardin S, Lemmouchi Y, Seymour L. Biomedical applications of degradable polyphosphazenes. Biotechnology and Bioengineering. 52: 102-8. PMID 18629856 DOI: 10.1002/(Sici)1097-0290(19961005)52:1<102::Aid-Bit10>3.0.Co;2-Q |
0.292 |
|
| 1999 |
Barrett LB, Logan A, Berry M, Ying W, Gonzalez AM, Baird A, Seymour LW. Targeted transfection of neuronal cells using a poly(D-lysine)-cholera-toxin b chain conjugate. Biochemical Society Transactions. 27: 851-7. PMID 10830116 DOI: 10.1042/Bst0270851 |
0.291 |
|
| 2015 |
Jakeman PG, Hills TE, Fisher KD, Seymour LW. Macrophages and their interactions with oncolytic viruses. Current Opinion in Pharmacology. 24: 23-29. PMID 26164569 DOI: 10.1016/J.Coph.2015.06.007 |
0.29 |
|
| 2008 |
Bazan-Peregrino M, Carlisle RC, Hernandez-Alcoceba R, Iggo R, Homicsko K, Fisher KD, Halldén G, Mautner V, Shen Y, Seymour LW. Comparison of molecular strategies for breast cancer virotherapy using oncolytic adenovirus. Human Gene Therapy. 19: 873-86. PMID 18710328 DOI: 10.1089/Hum.2008.047 |
0.288 |
|
| 2012 |
Walls GV, Lemos MC, Javid M, Bazan-Peregrino M, Jeyabalan J, Reed AA, Harding B, Tyler DJ, Stuckey DJ, Piret S, Christie PT, Ansorge O, Clarke K, Seymour L, Thakker RV. MEN1 gene replacement therapy reduces proliferation rates in a mouse model of pituitary adenomas. Cancer Research. 72: 5060-8. PMID 22915754 DOI: 10.1158/0008-5472.Can-12-1821 |
0.284 |
|
| 1995 |
Liu B, Earl HM, Baban D, Shoaibi M, Fabra A, Kerr DJ, Seymour LW. Melanoma cell lines express VEGF receptor KDR and respond to exogenously added VEGF. Biochemical and Biophysical Research Communications. 217: 721-7. PMID 8554590 DOI: 10.1006/Bbrc.1995.2832 |
0.283 |
|
| 2009 |
Morrison J, Briggs SS, Green NK, Thoma C, Fisher KD, Kehoe S, Seymour LW. Cetuximab retargeting of adenovirus via the epidermal growth factor receptor for treatment of intraperitoneal ovarian cancer. Human Gene Therapy. 20: 239-51. PMID 19257852 DOI: 10.1089/Hum.2008.167 |
0.282 |
|
| 1996 |
Wolfert MA, Schacht EH, Toncheva V, Ulbrich K, Nazarova O, Seymour LW. Characterization of vectors for gene therapy formed by self-assembly of DNA with synthetic block co-polymers. Human Gene Therapy. 7: 2123-33. PMID 8934226 DOI: 10.1089/hum.1996.7.17-2123 |
0.281 |
|
| 1991 |
Vansteenkiste S, Schacht E, Duncan R, Seymour L, Pawluczyk I, Baldwin R. Fate of glycosylated dextrans after in vivo administration Journal of Controlled Release. 16: 91-99. DOI: 10.1016/0168-3659(91)90033-A |
0.279 |
|
| 2011 |
Bachtarzi H, Stevenson M, Å ubr V, Ulbrich K, Seymour LW, Fisher KD. Targeting adenovirus gene delivery to activated tumour-associated vasculature via endothelial selectins. Journal of Controlled Release : Official Journal of the Controlled Release Society. 150: 196-203. PMID 20965218 DOI: 10.1016/j.jconrel.2010.10.011 |
0.277 |
|
| 2020 |
Lynn GM, Sedlik C, Baharom F, Zhu Y, Ramirez-Valdez RA, Coble VL, Tobin K, Nichols SR, Itzkowitz Y, Zaidi N, Gammon JM, Blobel NJ, Denizeau J, de la Rochere P, Francica BJ, ... ... Seymour LW, et al. Peptide-TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens. Nature Biotechnology. PMID 31932728 DOI: 10.1038/S41587-019-0390-X |
0.277 |
|
| 2005 |
Zhou QH, Miller DL, Carlisle RC, Seymour LW, Oupicky D. Ultrasound-enhanced transfection activity of HPMA-stabilized DNA polyplexes with prolonged plasma circulation. Journal of Controlled Release : Official Journal of the Controlled Release Society. 106: 416-27. PMID 15967534 DOI: 10.1016/J.Jconrel.2005.05.002 |
0.273 |
|
| 2016 |
Seymour LW, Fisher KD. Under Pressure: Elevated Blood Pressure Enhances Targeting of Tumors by Oncolytic Viruses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 24: 204-5. PMID 26906615 DOI: 10.1038/Mt.2016.19 |
0.273 |
|
| 1996 |
Baban D, Murray J, Earl H, Kerr D, Seymour L. Quantitative analysis of vascular endothelial growth factor expression in chronic lymphocytic leukaemia. International Journal of Oncology. 8: 29-34. DOI: 10.3892/Ijo.8.1.29 |
0.271 |
|
| 1999 |
Ward CM, Fisher KD, Seymour LW. A sensitive assay system for the determination of poly(L-lysine) concentration using turbidometry Journal of Bioactive and Compatible Polymers. 14: 122-136. DOI: 10.1177/088391159901400202 |
0.267 |
|
| 2001 |
Mulholland PJ, Ferry DR, Anderson D, Hussain SA, Young AM, Cook JE, Hodgkin E, Seymour LW, Kerr DJ. Pre-clinical and clinical study of QC12, a water-soluble, pro-drug of quercetin. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 12: 245-8. PMID 11300332 DOI: 10.1023/A:1008372017097 |
0.267 |
|
| 2016 |
Francica JR, Lynn GM, Laga R, Joyce MG, Ruckwardt TJ, Moribito KM, Chen M, Chaudhuri R, Zhang B, Sastry M, Ko K, Choe M, Pechar M, Georgiev IS, Kueltzo LA, ... Seymour LW, et al. Thermo-Responsive Polymer Nanoparticles Co-Deliver RSV F Trimers with a TLR-7/8 Adjuvant. Bioconjugate Chemistry. PMID 27583777 DOI: 10.1021/Acs.Bioconjchem.6B00370 |
0.266 |
|
| 2007 |
Fisher KD, Green NK, Hale A, Subr V, Ulbrich K, Seymour LW. Passive tumour targeting of polymer-coated adenovirus for cancer gene therapy. Journal of Drug Targeting. 15: 546-51. PMID 17671901 DOI: 10.1080/10611860701501014 |
0.265 |
|
| 2020 |
O'Cathail SM, Davis S, Holmes J, Brown R, Fisher K, Seymour L, Adams R, Good J, Sebag-Montefiore D, Maughan T, Hawkins MA. A phase 1 trial of the safety, tolerability and biological effects of intravenous Enadenotucirev, a novel oncolytic virus, in combination with chemoradiotherapy in locally advanced rectal cancer (CEDAR). Radiation Oncology (London, England). 15: 151. PMID 32532291 DOI: 10.1186/S13014-020-01593-5 |
0.265 |
|
| 1999 |
Anderson D, Ferry DR, Knox RJ, Andrews SJ, Downes AJ, Kerr DJ, Seymour LW. High-performance liquid chromatographic method for sensitive determination of the alkylating agent CB1954 in human plasma. Journal of Chromatography. B, Biomedical Sciences and Applications. 731: 293-8. PMID 10510783 DOI: 10.1016/S0378-4347(99)00245-5 |
0.262 |
|
| 2005 |
Read ML, Logan A, Seymour LW. Barriers to Gene Delivery Using Synthetic Vectors. Advances in Genetics. 53: 19-46. PMID 16243059 DOI: 10.1016/S0065-2660(05)53002-5 |
0.261 |
|
| 2005 |
Read ML, Logan A, Seymour LW. Barriers to gene delivery using synthetic vectors. Advances in Genetics. 53: 19-46. PMID 16240989 |
0.261 |
|
| 2001 |
Berry M, Gonzalez AM, Clarke W, Greenlees L, Barrett L, Tsang W, Seymour L, Bonadio J, Logan A, Baird A. Sustained effects of gene-activated matrices after CNS injury. Molecular and Cellular Neurosciences. 17: 706-16. PMID 11312606 DOI: 10.1006/Mcne.2001.0975 |
0.26 |
|
| 2016 |
Hills T, Jakeman PG, Carlisle RC, Klenerman P, Seymour LW, Cawood R. A Rapid-Response Humoral Vaccine Platform Exploiting Pre-Existing Non-Cognate Populations of Anti-Vaccine or Anti-Viral CD4+ T Helper Cells to Confirm B Cell Activation. Plos One. 11: e0166383. PMID 27861512 DOI: 10.1371/Journal.Pone.0166383 |
0.254 |
|
| 2000 |
Pechar M, Ulbrich K, Subr V, Seymour LW, Schacht EH. Poly(ethylene glycol) multiblock copolymer as a carrier of anti-cancer drug doxorubicin. Bioconjugate Chemistry. 11: 131-9. PMID 10725088 DOI: 10.1021/bc990092l |
0.254 |
|
| 2019 |
Francini N, Cochrane D, Illingworth S, Purdie L, Mantovani G, Fisher K, Seymour LW, Spain SG, Alexander C. Polyvalent diazonium polymers provide efficient protection of oncolytic adenovirus Enadenotucirev from neutralising antibodies while maintaining biological activity in vitro and in vivo. Bioconjugate Chemistry. PMID 30874432 DOI: 10.1021/acs.bioconjchem.9b00189 |
0.251 |
|
| 1988 |
Seymour LW. The specificity of recognition by isolated rat peritoneal macrophages of N-(2-hydroxypropyl)methacrylamide copolymers containing mannosamine European Journal of Medicinal Chemistry. 23: 353-358. DOI: 10.1016/0223-5234(88)90208-5 |
0.25 |
|
| 2014 |
Guinn BA, Braidwood L, Parker A, Peng KW, Seymour L. 8th international conference on oncolytic virus therapeutics. Human Gene Therapy. 25: 1062-84. PMID 25274574 DOI: 10.1089/Hum.2014.118 |
0.244 |
|
| 2010 |
Fisher KD, Seymour LW. HPMA copolymers for masking and retargeting of therapeutic viruses. Advanced Drug Delivery Reviews. 62: 240-5. PMID 20005911 DOI: 10.1016/j.addr.2009.12.003 |
0.24 |
|
| 2014 |
Kueberuwa G, Cawood R, Tedcastle A, Seymour LW. Tissue-specific attenuation of oncolytic sindbis virus without compromised genetic stability. Human Gene Therapy Methods. 25: 154-65. PMID 24568203 DOI: 10.1089/Hgtb.2013.202 |
0.24 |
|
| 2012 |
Soliman M, Nasanit R, Abulateefeh SR, Allen S, Davies MC, Briggs SS, Seymour LW, Preece JA, Grabowska AM, Watson SA, Alexander C. Multicomponent synthetic polymers with viral-mimetic chemistry for nucleic acid delivery. Molecular Pharmaceutics. 9: 1-13. PMID 22142438 DOI: 10.1021/mp200108q |
0.24 |
|
| 2002 |
Seymour LW. Delivering gene therapy. Journal of Drug Targeting. 10: 91. PMID 12074544 DOI: 10.1080/10611860290016676 |
0.239 |
|
| 2005 |
De Winne K, Seymour LW, Schacht EH. Synthesis and in vitro evaluation of macromolecular antitumour derivatives based on phenylenediamine mustard. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 24: 159-68. PMID 15661487 DOI: 10.1016/j.ejps.2004.09.006 |
0.234 |
|
| 2016 |
Lu W, Chen Q, Ying S, Xia X, Yu Z, Lui Y, Tranter G, Jin B, Song C, Seymour LW, Jiang S. Evolutionarily conserved primary TNF sequences relate to its primitive functions in cell death induction. Journal of Cell Science. 129: 108-20. PMID 26729029 DOI: 10.1242/Jcs.175463 |
0.233 |
|
| 2009 |
Liu WL, Stevenson M, Seymour LW, Fisher KD. Quantification of siRNA using competitive qPCR. Nucleic Acids Research. 37: e4. PMID 19004870 DOI: 10.1093/nar/gkn903 |
0.231 |
|
| 1997 |
Anderson D, Kerr DJ, Blesing C, Seymour LW. Simultaneous gas chromatographic-mass spectrophotometric determination of alpha-fluoro-beta-alanine and 5-fluorouracil in plasma. Journal of Chromatography. B, Biomedical Sciences and Applications. 688: 87-93. PMID 9029317 DOI: 10.1016/S0378-4347(97)88059-0 |
0.23 |
|
| 2009 |
Newman CM, Crosdale DJ, Fisher KD, Briggs SS, Norman KE, Seymour LW, Hellewell PG. P-selectin dependent targeting to inflamed endothelium of recombinant P-selectin glycoprotein ligand-1 immunoglobulin chimera-coated poly[N-(2-hydroxypropyl) methacrylamide]-DNA polyplexes in vivo visualised by intravital microscopy. The Journal of Gene Medicine. 11: 326-34. PMID 19219895 DOI: 10.1002/jgm.1294 |
0.229 |
|
| 2004 |
Green NK, Herbert CW, Hale SJ, Hale AB, Mautner V, Harkins R, Hermiston T, Ulbrich K, Fisher KD, Seymour LW. Extended plasma circulation time and decreased toxicity of polymer-coated adenovirus. Gene Therapy. 11: 1256-63. PMID 15215884 DOI: 10.1038/sj.gt.3302295 |
0.225 |
|
| 1990 |
Seymour LW, Ulbrich K, Strohalm J, Kopecek J, Duncan R. The pharmacokinetics of polymer-bound adriamycin. Biochemical Pharmacology. 39: 1125-31. PMID 2322298 DOI: 10.1016/0006-2952(90)90293-T |
0.225 |
|
| 2008 |
Green NK, Morrison J, Hale S, Briggs SS, Stevenson M, Subr V, Ulbrich K, Chandler L, Mautner V, Seymour LW, Fisher KD. Retargeting polymer-coated adenovirus to the FGF receptor allows productive infection and mediates efficacy in a peritoneal model of human ovarian cancer. The Journal of Gene Medicine. 10: 280-9. PMID 18214996 DOI: 10.1002/jgm.1121 |
0.223 |
|
| 2005 |
Read ML, Singh S, Ahmed Z, Stevenson M, Briggs SS, Oupicky D, Barrett LB, Spice R, Kendall M, Berry M, Preece JA, Logan A, Seymour LW. A versatile reducible polycation-based system for efficient delivery of a broad range of nucleic acids. Nucleic Acids Research. 33: e86. PMID 15914665 DOI: 10.1093/nar/gni085 |
0.223 |
|
| 2000 |
Oupický D, Howard KA, Konák C, Dash PR, Ulbrich K, Seymour LW. Steric stabilization of poly-L-Lysine/DNA complexes by the covalent attachment of semitelechelic poly[N-(2-hydroxypropyl)methacrylamide]. Bioconjugate Chemistry. 11: 492-501. PMID 10898570 DOI: 10.1021/bc990143e |
0.222 |
|
| 2012 |
Green NK, Hale A, Cawood R, Illingworth S, Herbert C, Hermiston T, Subr V, Ulbrich K, van Rooijen N, Seymour LW, Fisher KD. Tropism ablation and stealthing of oncolytic adenovirus enhances systemic delivery to tumors and improves virotherapy of cancer. Nanomedicine (London, England). 7: 1683-95. PMID 22709345 DOI: 10.2217/nnm.12.50 |
0.221 |
|
| 2007 |
Erban R, Chapman SJ, Fisher KD, Kevrekidis IG, Seymour LW. Dynamics of polydisperse irreversible adsorption: A pharmacological example Mathematical Models and Methods in Applied Sciences. 17: 759-781. DOI: 10.1142/S0218202507002091 |
0.217 |
|
| 1991 |
Seymour LW, Flanagan PA, al-Shamkhani A, Subr V, Ulbrich K, Cassidy J, Duncan R. Synthetic polymers conjugated to monoclonal antibodies: vehicles for tumour-targeted drug delivery. Selective Cancer Therapeutics. 7: 59-73. PMID 1754729 |
0.216 |
|
| 1995 |
Gore ME, Earl HM, Cassidy J, Tattersall M, Mansi J, Seymour L, Azab M. A phase II study of Tomudex in relapsed epithelial ovarian cancer. Annals of Oncology. 6: 724-725. PMID 8664196 DOI: 10.1093/Oxfordjournals.Annonc.A059291 |
0.216 |
|
| 2004 |
Carlisle RC, Etrych T, Briggs SS, Preece JA, Ulbrich K, Seymour LW. Polymer-coated polyethylenimine/DNA complexes designed for triggered activation by intracellular reduction. The Journal of Gene Medicine. 6: 337-44. PMID 15026995 DOI: 10.1002/jgm.525 |
0.211 |
|
| 2008 |
Carlisle RC, Benjamin R, Briggs SS, Sumner-Jones S, McIntosh J, Gill D, Hyde S, Nathwani A, Subr V, Ulbrich K, Seymour LW, Fisher KD. Coating of adeno-associated virus with reactive polymers can ablate virus tropism, enable retargeting and provide resistance to neutralising antisera. The Journal of Gene Medicine. 10: 400-11. PMID 18220318 DOI: 10.1002/jgm.1161 |
0.21 |
|
| 1992 |
Maeda H, Seymour LW, Miyamoto Y. Conjugates of anticancer agents and polymers: advantages of macromolecular therapeutics in vivo. Bioconjugate Chemistry. 3: 351-62. PMID 1420435 |
0.21 |
|
| 1994 |
Seymour LW. Soluble polymers for lectin-mediated drug targeting Advanced Drug Delivery Reviews. 14: 89-111. DOI: 10.1016/0169-409X(94)90007-8 |
0.209 |
|
| 2010 |
Willemsen RA, Pechar M, Carlisle RC, Schooten E, Pola R, Thompson AJ, Seymour LW, Ulbrich K. Multi-component polymeric system for tumour cell-specific gene delivery using a universal bungarotoxin linker. Pharmaceutical Research. 27: 2274-82. PMID 20300804 DOI: 10.1007/s11095-010-0088-8 |
0.208 |
|
| 2009 |
Sims K, Ahmed Z, Read ML, Cooper-Charles L, Gonzalez AM, Fisher KD, Berry M, Seymour LW, Logan A. In vitro evaluation of a 'stealth' adenoviral vector for targeted gene delivery to adult mammalian neurones. The Journal of Gene Medicine. 11: 335-44. PMID 19248141 DOI: 10.1002/jgm.1306 |
0.207 |
|
| 2011 |
Seki T, Carroll F, Illingworth S, Green N, Cawood R, Bachtarzi H, Subr V, Fisher KD, Seymour LW. Tumour necrosis factor-alpha increases extravasation of virus particles into tumour tissue by activating the Rho A/Rho kinase pathway. Journal of Controlled Release : Official Journal of the Controlled Release Society. 156: 381-9. PMID 21884739 DOI: 10.1016/j.jconrel.2011.08.022 |
0.207 |
|
| 2021 |
Wan PK, Ryan AJ, Seymour LW. Beyond cancer cells: Targeting the tumour microenvironment with gene therapy and armed oncolytic virus. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 33845199 DOI: 10.1016/j.ymthe.2021.04.015 |
0.205 |
|
| 1994 |
Cremers HFM, Seymour LW, Lam K, Los G, van Vugt M, Kwon G, Bae YH, Kim SW, Feijen J. Adriamycin-loaded albumin-heparin conjugate microspheres for intraperitoneal chemotherapy International Journal of Pharmaceutics. 110: 117-125. DOI: 10.1016/0378-5173(94)90149-X |
0.205 |
|
| 2012 |
Tedcastle A, Cawood R, Di Y, Fisher KD, Seymour LW. Virotherapy--cancer targeted pharmacology. Drug Discovery Today. 17: 215-20. PMID 22198165 DOI: 10.1016/j.drudis.2011.12.011 |
0.201 |
|
| 2006 |
Lyons M, Onion D, Green NK, Aslan K, Rajaratnam R, Bazan-Peregrino M, Phipps S, Hale S, Mautner V, Seymour LW, Fisher KD. Adenovirus type 5 interactions with human blood cells may compromise systemic delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 118-28. PMID 16580883 DOI: 10.1016/j.ymthe.2006.01.003 |
0.2 |
|
| 2009 |
Liu WL, Owen DP, Fisher KD, Seymour LW, Stevenson M. Establishment of a positive-readout reporter system for siRNAs. Journal of Rnai and Gene Silencing : An International Journal of Rna and Gene Targeting Research. 5: 331-8. PMID 19771230 |
0.199 |
|
| 2023 |
Su W, Seymour LW, Cawood R. AAV production in stable packaging cells requires expression of adenovirus 22/33K protein to allow episomal amplification of integrated rep/cap genes. Scientific Reports. 13: 21670. PMID 38066084 DOI: 10.1038/s41598-023-48901-z |
0.197 |
|
| 2006 |
Farrow PJ, Barrett LB, Stevenson M, Fisher KD, Finn J, Spice R, Allan MA, Berry M, Logan A, Seymour LW, Read ML. Cytoplasmic expression systems triggered by mRNA yield increased gene expression in post-mitotic neurons. Nucleic Acids Research. 34: e80. PMID 16835307 DOI: 10.1093/nar/gkl442 |
0.197 |
|
| 2013 |
Stevenson M, Carlisle R, Davies B, Preece C, Hammett M, Liu WL, Fisher KD, Ryan A, Scrable H, Seymour LW. Development of a Positive-readout Mouse Model of siRNA Pharmacodynamics. Molecular Therapy. Nucleic Acids. 2: e133. PMID 24253258 DOI: 10.1038/Mtna.2013.63 |
0.194 |
|
| 2012 |
Laga R, Carlisle R, Tangney M, Ulbrich K, Seymour LW. Polymer coatings for delivery of nucleic acid therapeutics. Journal of Controlled Release : Official Journal of the Controlled Release Society. 161: 537-53. PMID 22366547 DOI: 10.1016/j.jconrel.2012.02.013 |
0.193 |
|
| 1991 |
Seymour LW, Duncan R, Chytrý V, Strohalm J, Ulbrich K, Kopeček J. Intraperitoneal and subcutaneous retention of a soluble polymeric drug-carrier bearing galactose Journal of Controlled Release. 16: 255-262. DOI: 10.1016/0168-3659(91)90001-T |
0.19 |
|
| 2020 |
Wallis J, Katti P, Martin AM, Hills T, Seymour LW, Shenton DP, Carlisle RC. A liposome-based cancer vaccine for a rapid and high-titre anti-ErbB-2 antibody response. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 152: 105456. PMID 32653563 DOI: 10.1016/j.ejps.2020.105456 |
0.189 |
|
| 2017 |
Duffy MR, Fisher KD, Seymour LW. Making oncolytic virotherapy a clinical reality: the European contribution. Human Gene Therapy. PMID 28793793 DOI: 10.1089/hum.2017.112 |
0.187 |
|
| 2011 |
Bachtarzi H, Stevenson M, Subr V, Seymour LW, Fisher KD. E-selectin is a viable route of infection for polymer-coated adenovirus retargeting in TNF-α-activated human umbilical vein endothelial cells. Journal of Drug Targeting. 19: 690-700. PMID 21309681 DOI: 10.3109/1061186X.2010.547585 |
0.182 |
|
| 2022 |
Su W, Patrício MI, Duffy MR, Krakowiak JM, Seymour LW, Cawood R. Self-attenuating adenovirus enables production of recombinant adeno-associated virus for high manufacturing yield without contamination. Nature Communications. 13: 1182. PMID 35256603 DOI: 10.1038/s41467-022-28738-2 |
0.179 |
|
| 2007 |
Maruta F, Akita N, Nakayama J, Miyagawa S, Ismail T, Rowlands DC, Kerr DJ, Fisher KD, Seymour LW, Parker AL. Bacteriophage biopanning in human tumour biopsies to identify cancer-specific targeting ligands. Journal of Drug Targeting. 15: 311-9. PMID 17487700 DOI: 10.1080/10611860701195510 |
0.175 |
|
| 2013 |
Carlisle R, Choi J, Bazan-Peregrino M, Laga R, Subr V, Kostka L, Ulbrich K, Coussios CC, Seymour LW. Enhanced tumor uptake and penetration of virotherapy using polymer stealthing and focused ultrasound. Journal of the National Cancer Institute. 105: 1701-10. PMID 24168971 DOI: 10.1093/jnci/djt305 |
0.17 |
|
| 2008 |
Nasanit R, Iqbal P, Soliman M, Spencer N, Allen S, Davies MC, Briggs SS, Seymour LW, Preece JA, Alexander C. Combination dual responsive polypeptide vectors for enhanced gene delivery. Molecular Biosystems. 4: 741-5. PMID 18563248 DOI: 10.1039/b803262a |
0.169 |
|
| 2004 |
Bremner KH, Seymour LW, Logan A, Read ML. Factors influencing the ability of nuclear localization sequence peptides to enhance nonviral gene delivery. Bioconjugate Chemistry. 15: 152-61. PMID 14733595 DOI: 10.1021/bc034140k |
0.166 |
|
| 2019 |
Wahlich J, Desai A, Greco F, Hill K, Jones AT, Mrsny RJ, Pasut G, Perrie Y, Seib FP, Seymour LW, Uchegbu IF. Nanomedicines for the Delivery of Biologics. Pharmaceutics. 11. PMID 31058802 DOI: 10.3390/Pharmaceutics11050210 |
0.166 |
|
| 2000 |
Atuah KN, Seymour LW, Alpar HO. Stearylamine and polyethylenimine improve encapsulation of plasmid DNA into microspheres Journal of Pharmacy and Pharmacology. 52: 87. |
0.163 |
|
| 2023 |
Wan PK, Fernandes RA, Seymour LW. Oncolytic viruses and antibodies: are they more successful when delivered separately or when engineered as a single agent? Journal For Immunotherapy of Cancer. 11. PMID 37541690 DOI: 10.1136/jitc-2022-006518 |
0.163 |
|
| 2021 |
Morotti M, Albukhari A, Alsaadi A, Artibani M, Brenton JD, Curbishley SM, Dong T, Dustin ML, Hu Z, McGranahan N, Miller ML, Santana-Gonzalez L, Seymour LW, Shi T, Van Loo P, et al. Promises and challenges of adoptive T-cell therapies for solid tumours. British Journal of Cancer. PMID 33782566 DOI: 10.1038/s41416-021-01353-6 |
0.162 |
|
| 2012 |
Bazan-Peregrino M, Arvanitis CD, Rifai B, Seymour LW, Coussios CC. Ultrasound-induced cavitation enhances the delivery and therapeutic efficacy of an oncolytic virus in an in vitro model. Journal of Controlled Release : Official Journal of the Controlled Release Society. 157: 235-42. PMID 21982902 DOI: 10.1016/j.jconrel.2011.09.086 |
0.161 |
|
| 2003 |
Parker AL, Newman C, Briggs S, Seymour L, Sheridan PJ. Nonviral gene delivery: techniques and implications for molecular medicine. Expert Reviews in Molecular Medicine. 5: 1-15. PMID 14585173 DOI: 10.1017/S1462399403006562 |
0.159 |
|
| 2001 |
Pouton CW, Seymour LW. Key issues in non-viral gene delivery. Advanced Drug Delivery Reviews. 46: 187-203. PMID 11259840 DOI: 10.1016/S0169-409X(00)00133-2 |
0.159 |
|
| 1998 |
Pouton CW, Seymour LW. Key issues in non-viral gene delivery. Advanced Drug Delivery Reviews. 34: 3-19. PMID 10837667 |
0.159 |
|
| 2019 |
Lynn GM, Chytil P, Francica JR, Lagova A, Kueberuwa G, Ishizuka AS, Zaidi N, Ramirez-Valdez RA, Blobel NJ, Baharom F, Leal J, Wang AQ, Gerner MY, Etrych T, Ulbrich K, ... Seymour LW, et al. Impact of polymer-TLR-7/8 agonist (adjuvant) morphology on the potency and mechanism of CD8 T cell induction. Biomacromolecules. PMID 30608149 DOI: 10.1021/Acs.Biomac.8B01473 |
0.159 |
|
| 2002 |
Green NK, Seymour LW. Adenoviral vectors: systemic delivery and tumor targeting. Cancer Gene Therapy. 9: 1036-42. PMID 12522442 DOI: 10.1038/sj.cgt.7700541 |
0.158 |
|
| 1992 |
Seymour LW. Passive tumor targeting of soluble macromolecules and drug conjugates. Critical Reviews in Therapeutic Drug Carrier Systems. 9: 135-87. PMID 1386002 |
0.156 |
|
| 2008 |
Seymour LW. Cancer gene therapy: The challenge of delivery Biochemist. 30: 4-6. |
0.153 |
|
| 1996 |
Wolfert MA, Seymour LW. Atomic force microscopic analysis of the influence of the molecular weight of poly(L)lysine on the size of polyelectrolyte complexes formed with DNA. Gene Therapy. 3: 269-73. PMID 8646559 |
0.153 |
|
| 2009 |
Subr V, Kostka L, Selby-Milic T, Fisher K, Ulbrich K, Seymour LW, Carlisle RC. Coating of adenovirus type 5 with polymers containing quaternary amines prevents binding to blood components. Journal of Controlled Release : Official Journal of the Controlled Release Society. 135: 152-8. PMID 19166885 DOI: 10.1016/j.jconrel.2008.12.009 |
0.151 |
|
| 2002 |
Parker AL, Seymour LW. Targeting of polyelectrolyte RNA complexes to cell surface integrins as an efficient cytoplasmic transfection mechanism Journal of Bioactive and Compatible Polymers. 17: 229-238. |
0.149 |
|
| 2008 |
Chen HH, Cawood R, Seymour LW. Toward more effective gene delivery. Genome Biology. 9: 301. PMID 18226177 DOI: 10.1186/gb-2008-9-1-301 |
0.147 |
|
| 2020 |
Baugh R, Khalique H, Seymour LW. Convergent Evolution by Cancer and Viruses in Evading the NKG2D Immune Response. Cancers. 12. PMID 33352921 DOI: 10.3390/cancers12123827 |
0.147 |
|
| 2020 |
Baugh R, Khalique H, Seymour LW. Convergent Evolution by Cancer and Viruses in Evading the NKG2D Immune Response. Cancers. 12. PMID 33352921 DOI: 10.3390/cancers12123827 |
0.147 |
|
| 2012 |
Cawood R, Hills T, Wong SL, Alamoudi AA, Beadle S, Fisher KD, Seymour LW. Recombinant viral vaccines for cancer. Trends in Molecular Medicine. 18: 564-74. PMID 22917663 DOI: 10.1016/j.molmed.2012.07.007 |
0.145 |
|
| 2021 |
Pilger D, Seymour LW, Jackson SP. Interfaces between cellular responses to DNA damage and cancer immunotherapy. Genes & Development. PMID 33888558 DOI: 10.1101/gad.348314.121 |
0.144 |
|
| 2013 |
Bazan-Peregrino M, Rifai B, Carlisle RC, Choi J, Arvanitis CD, Seymour LW, Coussios CC. Cavitation-enhanced delivery of a replicating oncolytic adenovirus to tumors using focused ultrasound. Journal of Controlled Release : Official Journal of the Controlled Release Society. 169: 40-7. PMID 23562636 DOI: 10.1016/j.jconrel.2013.03.017 |
0.143 |
|
| 1994 |
Seymour LW, Duncan R, Duffy J, Ng SY, Heller J. Poly (ortho ester) matrices for controlled release of the antitumour agent 5-fluorouracil Journal of Controlled Release. 31: 201-206. DOI: 10.1016/0168-3659(94)00046-8 |
0.143 |
|
| 2006 |
Akita N, Maruta F, Seymour LW, Kerr DJ, Parker AL, Asai T, Oku N, Nakayama J, Miyagawa S. Identification of oligopeptides binding to peritoneal tumors of gastric cancer. Cancer Science. 97: 1075-81. PMID 16984380 DOI: 10.1111/j.1349-7006.2006.00291.x |
0.143 |
|
| 2022 |
Lee SY, George J, Nagel D, Ye H, Seymour L. Optogenetically Engineered Neurons Differentiated from Human SH-SY5Y Cells Survived and Expressed ChR2 in 3D Hydrogel. Biomedicines. 10. PMID 35884839 DOI: 10.3390/biomedicines10071534 |
0.141 |
|
| 2011 |
Arvanitis CD, Bazan-Peregrino M, Rifai B, Seymour LW, Coussios CC. Cavitation-enhanced extravasation for drug delivery. Ultrasound in Medicine & Biology. 37: 1838-52. PMID 21963037 DOI: 10.1016/j.ultrasmedbio.2011.08.004 |
0.135 |
|
| 2009 |
Carlisle RC, Di Y, Cerny AM, Sonnen AF, Sim RB, Green NK, Subr V, Ulbrich K, Gilbert RJ, Fisher KD, Finberg RW, Seymour LW. Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1. Blood. 113: 1909-18. PMID 19131551 DOI: 10.1182/Blood-2008-09-178459 |
0.133 |
|
| 2009 |
Seymour LW, Ferry DR, Kerr DJ, Rea D, Whitlock M, Poyner R, Boivin C, Hesslewood S, Twelves C, Blackie R, Schatzlein A, Jodrell D, Bissett D, Calvert H, Lind M, et al. Phase II studies of polymer-doxorubicin (PK1, FCE28068) in the treatment of breast, lung and colorectal cancer. International Journal of Oncology. 34: 1629-36. PMID 19424581 DOI: 10.3892/ijo_00000293 |
0.13 |
|
| 2013 |
Carlisle R, Seymour LW, Coussios CC. Targeting of liposomes via PSGL1 for enhanced tumor accumulation. Pharmaceutical Research. 30: 352-61. PMID 22992830 DOI: 10.1007/s11095-012-0875-5 |
0.128 |
|
| 2009 |
Cawood R, Chen HH, Carroll F, Bazan-Peregrino M, van Rooijen N, Seymour LW. Use of tissue-specific microRNA to control pathology of wild-type adenovirus without attenuation of its ability to kill cancer cells. Plos Pathogens. 5: e1000440. PMID 19461878 DOI: 10.1371/journal.ppat.1000440 |
0.126 |
|
| 2009 |
El-Sherbini YM, Stevenson MM, Seymour LW, Wade-Martins R. Quantitative characterization of cell transduction by HSV-1 amplicons using flow cytometry and real-time PCR. Journal of Virological Methods. 159: 160-6. PMID 19490970 DOI: 10.1016/j.jviromet.2009.03.018 |
0.125 |
|
| 2018 |
Lee SY, George JH, Nagel DA, Ye H, Kueberuwa G, Seymour LW. Optogenetic control of iPS cell-derived neurons in 2D and 3D culture systems using channelrhodopsin-2 expressed by the SYN1 and CaMKII promoters. Journal of Tissue Engineering and Regenerative Medicine. PMID 30550638 DOI: 10.1002/term.2786 |
0.123 |
|
| 2003 |
Seymour LW, Fisher KD, Green NK, Hale SJ, Lyons M, Mautner V, Nicum S, Onion D, Oupicky D, Stevenson M, Ulbrich K. Adenovirus retargeting and systemic delivery. Ernst Schering Research Foundation Workshop. 107-14. PMID 12894454 DOI: 10.1007/978-3-662-05352-2_8 |
0.123 |
|
| 2002 |
Fisher KD, Hermiston T, Seymour LW. Gene transfer and cell-based therapies Current Opinion in Molecular Therapeutics. 4: 289. |
0.123 |
|
| 2021 |
Khalique H, Baugh R, Dyer A, Scott EM, Frost S, Larkin S, Lei-Rossmann J, Seymour LW. Oncolytic herpesvirus expressing PD-L1 BiTE for cancer therapy: exploiting tumor immune suppression as an opportunity for targeted immunotherapy. Journal For Immunotherapy of Cancer. 9. PMID 33820820 DOI: 10.1136/jitc-2020-001292 |
0.122 |
|
| 2011 |
Chen HH, Cawood R, El-Sherbini Y, Purdie L, Bazan-Peregrino M, Seymour LW, Carlisle RC. Active adenoviral vascular penetration by targeted formation of heterocellular endothelial-epithelial syncytia. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 67-75. PMID 20877345 DOI: 10.1038/mt.2010.209 |
0.121 |
|
| 2013 |
Thoma C, Bachy V, Seaton P, Green NK, Greaves DR, Klavinskis L, Seymour LW, Morrison J. Adenovirus serotype 11 causes less long-term intraperitoneal inflammation than serotype 5: implications for ovarian cancer therapy. Virology. 447: 74-83. PMID 24210101 DOI: 10.1016/j.virol.2013.08.032 |
0.121 |
|
| 1996 |
Seymour LW, Soyez H, De Marre A, Shoaibi MA, Schacht EH. Polymeric prodrugs of mitomycin C designed for tumour tropism and sustained activation. Anti-Cancer Drug Design. 11: 351-65. PMID 8765529 |
0.12 |
|
| 2008 |
Seymour LW, Cawood R, Fisher KD. Cellular carriers or free viruses? Current Opinion in Molecular Therapeutics. 10: 321-2. PMID 18683095 |
0.114 |
|
| 2010 |
Xu X, Cowley S, Flaim CJ, James W, Seymour LW, Cui Z. Enhancement of cell recovery for dissociated human embryonic stem cells after cryopreservation. Biotechnology Progress. 26: 781-8. PMID 20014103 DOI: 10.1002/Btpr.358 |
0.111 |
|
| 2011 |
Cawood R, Wong SL, Di Y, Baban DF, Seymour LW. MicroRNA controlled adenovirus mediates anti-cancer efficacy without affecting endogenous microRNA activity. Plos One. 6: e16152. PMID 21264344 DOI: 10.1371/journal.pone.0016152 |
0.111 |
|
| 2010 |
Soliman M, Nasanit R, Allen S, Davies MC, Briggs SS, Seymour LW, Preece JA, Alexander C. Interaction of reducible polypeptide gene delivery vectors with supported lipid bilayers: Pore formation and structure-function relationships Soft Matter. 6: 2517-2524. DOI: 10.1039/b927204f |
0.111 |
|
| 2003 |
Kerr DJ, Seymour LW, Maruta F. Gene therapy for colorectal cancer. Expert Opinion On Biological Therapy. 3: 779-88. PMID 12880378 DOI: 10.1517/14712598.3.5.779 |
0.11 |
|
| 2010 |
Xu X, Cowley S, Flaim CJ, James W, Seymour L, Cui Z. The roles of apoptotic pathways in the low recovery rate after cryopreservation of dissociated human embryonic stem cells. Biotechnology Progress. 26: 827-37. PMID 20077485 DOI: 10.1002/Btpr.368 |
0.107 |
|
| 2005 |
Pearce OM, Fisher KD, Humphries J, Seymour LW, Smith A, Davis BG. Glycoviruses: chemical glycosylation retargets adenoviral gene transfer. Angewandte Chemie (International Ed. in English). 44: 1057-61. PMID 15688429 DOI: 10.1002/Anie.200461832 |
0.107 |
|
| 2001 |
Bremner KH, Seymour LW, Pouton CW. Harnessing nuclear localization pathways for transgene delivery. Current Opinion in Molecular Therapeutics. 3: 170-7. PMID 11338930 |
0.1 |
|
| 2021 |
Fisher K, Hazini A, Seymour LW. Tackling HLA Deficiencies Head on with Oncolytic Viruses. Cancers. 13. PMID 33578735 DOI: 10.3390/cancers13040719 |
0.1 |
|
| 1996 |
Seymour LW, Shoaibi MA, Martin A, Ahmed A, Elvin P, Kerr DJ, Wakelam MJ. Vascular endothelial growth factor stimulates protein kinase C-dependent phospholipase D activity in endothelial cells. Laboratory Investigation; a Journal of Technical Methods and Pathology. 75: 427-37. PMID 8804365 |
0.098 |
|
| 1995 |
Anderson DA, Vansteenkiste S, Schacht EH, Sen SK, Seymour LW. In vitro binding specificity of glycosylated dextrans to the asialoglycoprotein receptor of primary hepatocytes European Journal of Pharmaceutical Sciences. 3: 339-345. DOI: 10.1016/0928-0987(95)00022-4 |
0.095 |
|
| 2006 |
Seymour LW. The future of gene therapy in the UK. Trends in Biotechnology. 24: 347-9. PMID 16782218 DOI: 10.1016/j.tibtech.2006.06.002 |
0.088 |
|
| 1995 |
Liu B, Anderson D, Ferry DR, Seymour LW, de Takats PG, Kerr DJ. Determination of quercetin in human plasma using reversed-phase high-performance liquid chromatography. Journal of Chromatography. B, Biomedical Applications. 666: 149-55. PMID 7655613 DOI: 10.1016/0378-4347(94)00549-K |
0.083 |
|
| 2003 |
Read ML, Stevenson M, Farrow PJ, Barrett LB, Seymour LW. RNA-based therapeutic strategies for cancer Expert Opinion On Therapeutic Patents. 13: 627-638. DOI: 10.1517/13543776.13.5.627 |
0.082 |
|
| 2012 |
Seymour LW, Thrasher AJ. Gene therapy matures in the clinic. Nature Biotechnology. 30: 588-93. PMID 22781675 DOI: 10.1038/nbt.2290 |
0.082 |
|
| 2009 |
Seymour LW, Fisher KD. Preclinical screening of gene therapy in human tissues. Human Gene Therapy. 20: 291-2. PMID 19348049 DOI: 10.1089/hum.2009.1309 |
0.079 |
|
| 2009 |
Liu WL, Green N, Seymour LW, Stevenson M. Paclitaxel combined with siRNA targeting HPV16 oncogenes improves cytotoxicity for cervical carcinoma. Cancer Gene Therapy. 16: 764-75. PMID 19363466 DOI: 10.1038/cgt.2009.24 |
0.07 |
|
| 2006 |
Shimizu A, Maruta F, Akita N, Miwa S, Seymour LW, Kerr DJ, Parker AL, Miyagawa S. Identification of an oligopeptide binding to hepatocellular carcinoma. Oncology. 71: 136-45. PMID 17341891 DOI: 10.1159/000100479 |
0.069 |
|
| 2010 |
Kueberuwa G, Cawood R, Seymour LW. Blood compatibility of enveloped viruses. Current Opinion in Molecular Therapeutics. 12: 412-20. PMID 20677092 |
0.067 |
|
| 2015 |
Jakeman PG, Hills TE, Fisher KD, Seymour LW. Macrophages and their interactions with oncolytic viruses Current Opinion in Pharmacology. 24: 23-29. DOI: 10.1016/j.coph.2015.06.007 |
0.056 |
|
| 2011 |
Seymour LW. Oncolytic virotherapy: combining first-rate science with an unmet clinical need. Human Gene Therapy. 22: 387-8. PMID 21486159 DOI: 10.1089/hum.2011.3220 |
0.041 |
|
| 2011 |
Seymour LW, Fisher KD. Adenovirus: teaching an old dog new tricks. Human Gene Therapy. 22: 1041-2. PMID 21932993 DOI: 10.1089/hum.2011.2517 |
0.036 |
|
| 2003 |
Read ML, Farrow PJ, Seymour LW. Emerging developments in RNA therapeutics. Expert Opinion On Therapeutic Targets. 7: 299-303. PMID 12667105 DOI: 10.1517/14728222.7.2.299 |
0.036 |
|
| 1903 |
Seymour LW. THE ABORTIVE TREATMENT OF SMALL-POX The Lancet. 161: 1127-1128. |
0.023 |
|
| 2003 |
Seymour LW. Trial and error. Lancet. 361: 1568. PMID 12737907 DOI: 10.1016/S0140-6736(03)13210-2 |
0.016 |
|
| 1998 |
Pouton C, Seymour LW. Preface Advanced Drug Delivery Reviews. 34: 1-2. DOI: 10.1016/S0169-409X(98)00080-5 |
0.01 |
|
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