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Douglas B. Stairs, Ph.D. - Publications

Affiliations: 
2004 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Cell Biology, Genetics
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Chalmers FE, Mogre S, Rimal B, Son J, Patterson AD, Stairs DB, Glick AB. The unfolded protein response gene Ire1α is required for tissue renewal and normal differentiation in the mouse tongue and esophagus. Developmental Biology. 492: 59-70. PMID 36179879 DOI: 10.1016/j.ydbio.2022.09.009  0.305
2020 Chalmers FE, Stairs DB, Glick AB. Abstract 5839: The unfolded protein response gene Ire1α is required for tissue renewal and normal differentiation in the mouse tongue and esophagus Cancer Research. 80: 5839-5839. DOI: 10.1158/1538-7445.Am2020-5839  0.382
2018 Lehman HL, Kidacki M, Warrick JI, Stairs DB. NFkB hyperactivation causes invasion of esophageal squamous cell carcinoma with EGFR overexpression and p120-catenin down-regulation. Oncotarget. 9: 11180-11196. PMID 29541406 DOI: 10.18632/Oncotarget.24358  0.376
2017 Kidacki M, Lehman HL, Green MV, Warrick JI, Stairs DB. p120-Catenin Downregulation and PIK3CA Mutations Cooperate to Induce Invasion through MMP1 in HNSCC. Molecular Cancer Research : McR. PMID 28637905 DOI: 10.1158/1541-7786.Mcr-17-0108  0.314
2016 Karagoz K, Lehman HL, Stairs DB, Sinha R, Arga KY. Proteomic and Metabolic Signatures of Esophageal Squamous Cell Carcinoma. Current Cancer Drug Targets. PMID 26845434 DOI: 10.2174/1568009616666160203113721  0.38
2015 Lehman HL, Yang X, Welsh PA, Stairs DB. p120-catenin down-regulation and epidermal growth factor receptor overexpression results in a transformed epithelium that mimics esophageal squamous cell carcinoma. The American Journal of Pathology. 185: 240-51. PMID 25529795 DOI: 10.1016/J.Ajpath.2014.09.008  0.353
2014 Vega ME, Giroux V, Natsuizaka M, Liu M, Klein-Szanto AJ, Stairs DB, Nakagawa H, Wang KK, Wang TC, Lynch JP, Rustgi AK. Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4. Cell Cycle (Georgetown, Tex.). 13: 3857-66. PMID 25558829 DOI: 10.4161/15384101.2014.972875  0.35
2012 Chen CC, Stairs DB, Boxer RB, Belka GK, Horseman ND, Alvarez JV, Chodosh LA. Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways. Genes & Development. 26: 2154-68. PMID 23028142 DOI: 10.1101/Gad.197343.112  0.751
2011 Kong J, Crissey MA, Stairs DB, Sepulveda AR, Lynch JP. Cox2 and β-catenin/T-cell factor signaling intestinalize human esophageal keratinocytes when cultured under organotypic conditions. Neoplasia (New York, N.Y.). 13: 792-805. PMID 21969813 DOI: 10.1593/Neo.11788  0.375
2011 Stairs DB, Bayne LJ, Rhoades B, Vega ME, Waldron TJ, Kalabis J, Klein-Szanto A, Lee JS, Katz JP, Diehl JA, Reynolds AB, Vonderheide RH, Rustgi AK. Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene. Cancer Cell. 19: 470-83. PMID 21481789 DOI: 10.1016/J.Ccr.2011.02.007  0.315
2011 Natsuizaka M, Ohashi S, Naganuma S, Kalman RA, Ohyama A, Rhoades B, Vega ME, Stairs DB, Klein-Szanto AJ, Diehl JA, Basu D, Herlyn M, Pear WS, Nakagawa H. Abstract 5194: Notch regulates squamous differentiation, cell plasticity and tumor heterogeneity in esophageal carcinoma Cancer Research. 71: 5194-5194. DOI: 10.1158/1538-7445.Am2011-5194  0.407
2011 Stairs DB, Bayne LJ, Rhoades B, Vega ME, Nakagawa H, Klein-Szanto AJ, Katz JP, Reynolds AB, Vonderheide RH, Rustgi AK. Loss of P120-Catenin Results in Esophageal Tumorigenesis, Involving the Recruitment of Immature Myeloid Cells to the Tumor Microenvironment Gastroenterology. 140: S-182. DOI: 10.1016/S0016-5085(11)60735-X  0.302
2010 Chen CC, Boxer RB, Stairs DB, Portocarrero CP, Horton RH, Alvarez JV, Birnbaum MJ, Chodosh LA. Akt is required for Stat5 activation and mammary differentiation. Breast Cancer Research : Bcr. 12: R72. PMID 20849614 DOI: 10.1186/Bcr2640  0.748
2010 Kong J, Stairs DB, Lynch JP. Modelling Barrett's oesophagus. Biochemical Society Transactions. 38: 321-6. PMID 20298176 DOI: 10.1042/Bst0380321  0.337
2010 Rustgi AK, Stairs DB, Grugan KD, Wong GS, Vega ME, Kalabis J, Nakagawa H, Gimotty PA, Klein-Szanto AJ, Diehl JA, Herlyn M. Abstract CN04-03: Esophageal cancer and the tumor microenvironment Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-Cn04-03  0.342
2010 Ohashi S, Natsuizaka M, Kalman RA, Yang Y, Stairs D, Katz JP, Pear WS, Klein-Szanto AJ, Nakagawa H. 185 NOTCH3 Activation at the Onset of Esophageal Squamous Epithelial Differentiation Gastroenterology. 138: S-34. DOI: 10.1016/S0016-5085(10)60156-4  0.349
2010 Nakagawa M, Ohashi S, Natsuizaka M, Vega ME, Stairs D, Klein-Szanto AJ, Diehl JA, Pear WS, Nakagawa H, Rustgi AK. 184 Cyclin D1 and EGFR Promote Invasive Growth of Human Esophageal Epithelial Cells in Concert With Impaired Notch Signaling Gastroenterology. 138: S-34. DOI: 10.1016/S0016-5085(10)60155-2  0.316
2009 Bass AJ, Watanabe H, Mermel CH, Yu S, Perner S, Verhaak RG, Kim SY, Wardwell L, Tamayo P, Gat-Viks I, Ramos AH, Woo MS, Weir BA, Getz G, Beroukhim R, ... ... Stairs DB, et al. SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nature Genetics. 41: 1238-42. PMID 19801978 DOI: 10.1038/Ng.465  0.356
2009 Ohashi S, Nakagawa M, Natsuizaka M, Stairs DB, Grugan KD, Kalabis J, Wong G, Yang Y, Klein-Szanto AJ, Herlyn M, Pear WS, Katz JP, Nakagawa H. 540 Epithelial Reconstitution Reveals Regulation of Differentiation and Cell Fate Decisions Through a Novel Interplay Between the Notch Signaling and Essential Cancer Genes in Esophageal Carcinogenesis Gastroenterology. 136: A-83. DOI: 10.1016/S0016-5085(09)60375-9  0.347
2008 Yang Y, Stairs DB, Michaylira CZ, Lee JJ, Kalabis J, Grugan KD, Andl CD, Budo D, Pear WS, Katz JP, Rustgi AK, Nakagawa H. M2010 Notch Signaling Regulates Esophageal Epithelial Homeostasis and Tumor Progression Gastroenterology. 134: A-450. DOI: 10.1016/S0016-5085(08)62103-4  0.313
2007 Okawa T, Michaylira CZ, Kalabis J, Stairs DB, Nakagawa H, Andl CD, Johnstone CN, Klein-Szanto AJ, El-Deiry WS, Cukierman E, Herlyn M, Rustgi AK. The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation. Genes & Development. 21: 2788-803. PMID 17974918 DOI: 10.1101/Gad.1544507  0.393
2007 Takaoka M, Kim SH, Okawa T, Michaylira CZ, Stairs DB, Johnstone CN, Andl CD, Rhoades B, Lee JJ, Klein-Szanto AJ, El-Deiry WS, Nakagawa H. IGFBP-3 regulates esophageal tumor growth through IGF-dependent and independent mechanisms. Cancer Biology & Therapy. 6: 534-40. PMID 17457048 DOI: 10.4161/Cbt.6.4.3832  0.362
2007 Sarkisian CJ, Keister BA, Stairs DB, Boxer RB, Moody SE, Chodosh LA. Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis. Nature Cell Biology. 9: 493-505. PMID 17450133 DOI: 10.1038/Ncb1567  0.587
2006 Boxer RB, Stairs DB, Dugan KD, Notarfrancesco KL, Portocarrero CP, Keister BA, Belka GK, Cho H, Rathmell JC, Thompson CB, Birnbaum MJ, Chodosh LA. Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation. Cell Metabolism. 4: 475-90. PMID 17141631 DOI: 10.1016/J.Cmet.2006.10.011  0.724
2005 Stairs DB, Notarfrancesco KL, Chodosh LA. The serine/threonine kinase, Krct, affects endbud morphogenesis during murine mammary gland development. Transgenic Research. 14: 919-40. PMID 16315096 DOI: 10.1007/S11248-005-1806-6  0.614
2000 Chodosh LA, Gardner HP, Rajan JV, Stairs DB, Marquis ST, Leder PA. Protein kinase expression during murine mammary development. Developmental Biology. 219: 259-76. PMID 10694421 DOI: 10.1006/Dbio.2000.9614  0.607
1999 Chodosh LA, D'Cruz CM, Gardner HP, Ha SI, Marquis ST, Rajan JV, Stairs DB, Wang JY, Wang M. Mammary gland development, reproductive history, and breast cancer risk. Cancer Research. 59: 1765-1771s; discussi. PMID 10197594  0.701
1998 Stairs DB, Perry Gardner H, Ha SI, Copeland NG, Gilbert DJ, Jenkins NA, Chodosh LA. Cloning and characterization of Krct, a member of a novel subfamily of serine/threonine kinases. Human Molecular Genetics. 7: 2157-66. PMID 9817935 DOI: 10.1093/Hmg/7.13.2157  0.607
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