Andrew C. Larner - Publications

Affiliations: 
Cleveland State University, Cleveland, OH, United States 
Area:
Molecular Biology

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Grillo M, Palmer C, Holmes N, Sang F, Larner AC, Bhosale R, Shaw PE. Stat3 oxidation-dependent regulation of gene expression impacts on developmental processes and involves cooperation with Hif-1α. Plos One. 15: e0244255. PMID 33332446 DOI: 10.1371/journal.pone.0244255  0.393
2018 Cantwell MT, Farrar JS, Lownik JC, Meier JA, Hyun M, Raje V, Waters MR, Celi FS, Conrad DH, Harris TE, Larner AC. STAT3 suppresses Wnt/β-catenin signaling during the induction phase of primary Myf5+ brown adipogenesis. Cytokine. PMID 29934048 DOI: 10.1016/J.Cyto.2018.05.023  0.367
2018 Ziegler PK, Bollrath J, Pallangyo CK, Matsutani T, Canli Ö, De Oliveira T, Diamanti MA, Müller N, Gamrekelashvili J, Putoczki T, Horst D, Mankan AK, Öner MG, Müller S, Müller-Höcker J, ... ... Larner AC, et al. Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis. Cell. PMID 29909986 DOI: 10.1016/J.Cell.2018.05.028  0.348
2017 Meier JA, Hyun M, Cantwell M, Raza A, Mertens C, Raje V, Sisler J, Tracy E, Torres-Odio S, Gispert S, Shaw PE, Baumann H, Bandyopadhyay D, Takabe K, Larner AC. Stress-induced dynamic regulation of mitochondrial STAT3 and its association with cyclophilin D reduce mitochondrial ROS production. Science Signaling. 10. PMID 28351946 DOI: 10.1126/Scisignal.Aag2588  0.464
2016 Raje V, Derecka M, Cantwell M, Meier J, Szczepanek K, Sisler JD, Strobl B, Gamero A, Harris TE, Larner AC. Kinase inactive Tyrosine kinase (Tyk2) Supports Differentiation of Brown fat Cells. Endocrinology. en20152048. PMID 27802075 DOI: 10.1210/En.2015-2048  0.461
2015 Sisler JD, Morgan M, Raje V, Grande RC, Derecka M, Meier J, Cantwell M, Szczepanek K, Korzun WJ, Lesnefsky EJ, Harris TE, Croniger CM, Larner AC. The Signal Transducer and Activator of Transcription 1 (STAT1) Inhibits Mitochondrial Biogenesis in Liver and Fatty Acid Oxidation in Adipocytes. Plos One. 10: e0144444. PMID 26689548 DOI: 10.1371/Journal.Pone.0144444  0.479
2015 Szczepanek K, Xu A, Hu Y, Thompson J, He J, Larner AC, Salloum FN, Chen Q, Lesnefsky EJ. Cardioprotective function of mitochondrial-targeted and transcriptionally inactive STAT3 against ischemia and reperfusion injury. Basic Research in Cardiology. 110: 53. PMID 26358226 DOI: 10.1007/S00395-015-0509-2  0.439
2014 Meier JA, Larner AC. Toward a new STATe: the role of STATs in mitochondrial function. Seminars in Immunology. 26: 20-8. PMID 24434063 DOI: 10.1016/J.Smim.2013.12.005  0.497
2014 Meier J, Raza A, Yamada A, Dai Y, Chen S, Grant S, Takabe K, Larner A. 107 Cytokine. 70: 53. DOI: 10.1016/J.Cyto.2014.07.114  0.474
2013 Zhang Q, Raje V, Yakovlev VA, Yacoub A, Szczepanek K, Meier J, Derecka M, Chen Q, Hu Y, Sisler J, Hamed H, Lesnefsky EJ, Valerie K, Dent P, Larner AC. Mitochondrial localized Stat3 promotes breast cancer growth via phosphorylation of serine 727. The Journal of Biological Chemistry. 288: 31280-8. PMID 24019511 DOI: 10.1074/Jbc.M113.505057  0.49
2013 Ross T, Szczepanek K, Bowler E, Hu Y, Larner A, Lesnefsky EJ, Chen Q. Reverse electron flow-mediated ROS generation in ischemia-damaged mitochondria: role of complex I inhibition vs. depolarization of inner mitochondrial membrane. Biochimica Et Biophysica Acta. 1830: 4537-42. PMID 23747300 DOI: 10.1016/J.Bbagen.2013.05.035  0.364
2013 Tammineni P, Anugula C, Mohammed F, Anjaneyulu M, Larner AC, Sepuri NB. The import of the transcription factor STAT3 into mitochondria depends on GRIM-19, a component of the electron transport chain. The Journal of Biological Chemistry. 288: 4723-32. PMID 23271731 DOI: 10.1074/Jbc.M112.378984  0.514
2013 Sisler J, Szelag M, Raje V, Derecka M, Szczepanek K, Lesnefsky E, Larner AC. 247 : Stat1 inhibits mitochondrial biogenesis Cytokine. 63: 301. DOI: 10.1016/J.Cyto.2013.06.250  0.415
2012 Derecka M, Gornicka A, Koralov SB, Szczepanek K, Morgan M, Raje V, Sisler J, Zhang Q, Otero D, Cichy J, Rajewsky K, Shimoda K, Poli V, Strobl B, Pellegrini S, ... ... Larner AC, et al. Tyk2 and Stat3 regulate brown adipose tissue differentiation and obesity. Cell Metabolism. 16: 814-24. PMID 23217260 DOI: 10.1016/J.Cmet.2012.11.005  0.355
2012 Szczepanek K, Lesnefsky EJ, Larner AC. Multi-tasking: nuclear transcription factors with novel roles in the mitochondria. Trends in Cell Biology. 22: 429-37. PMID 22705015 DOI: 10.1016/J.Tcb.2012.05.001  0.429
2012 Szczepanek K, Chen Q, Larner AC, Lesnefsky EJ. Cytoprotection by the modulation of mitochondrial electron transport chain: the emerging role of mitochondrial STAT3. Mitochondrion. 12: 180-9. PMID 21930250 DOI: 10.1016/J.Mito.2011.08.011  0.423
2011 Zhang Q, Sturgill JL, Kmieciak M, Szczepanek K, Derecka M, Koebel C, Graham LJ, Dai Y, Chen S, Grant S, Cichy J, Shimoda K, Gamero A, Manjili M, Bear H, ... ... Larner AC, et al. The role of Tyk2 in regulation of breast cancer growth. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 31: 671-7. PMID 21864028 DOI: 10.1089/Jir.2011.0023  0.482
2011 Szczepanek K, Chen Q, Derecka M, Salloum FN, Zhang Q, Szelag M, Cichy J, Kukreja RC, Dulak J, Lesnefsky EJ, Larner AC. Mitochondrial-targeted Signal transducer and activator of transcription 3 (STAT3) protects against ischemia-induced changes in the electron transport chain and the generation of reactive oxygen species. The Journal of Biological Chemistry. 286: 29610-20. PMID 21715323 DOI: 10.1074/Jbc.M111.226209  0.464
2010 Park MA, Mitchell C, Zhang G, Yacoub A, Allegood J, Häussinger D, Reinehr R, Larner A, Spiegel S, Fisher PB, Voelkel-Johnson C, Ogretmen B, Grant S, Dent P. Vorinostat and sorafenib increase CD95 activation in gastrointestinal tumor cells through a Ca(2+)-de novo ceramide-PP2A-reactive oxygen species-dependent signaling pathway. Cancer Research. 70: 6313-24. PMID 20631069 DOI: 10.1158/0008-5472.Can-10-0999  0.322
2010 Sisler JD, Szelag M, Potla R, Zhang Q, Szczepanek K, Derecka M, Wegrzyn J, Dulak J, Hamed H, Cichy J, Chen X, Baker DP, Dent P, Feldman GM, Shadel G, ... Larner AC, et al. PS1-58 The role of STAT1 in regulation of mitochondrial gene expression Cytokine. 52: 29-29. DOI: 10.1016/J.Cyto.2010.07.130  0.755
2009 Gough DJ, Corlett A, Schlessinger K, Wegrzyn J, Larner AC, Levy DE. Mitochondrial STAT3 supports Ras-dependent oncogenic transformation. Science (New York, N.Y.). 324: 1713-6. PMID 19556508 DOI: 10.1126/Science.1171721  0.442
2009 Wegrzyn J, Potla R, Chwae YJ, Sepuri NB, Zhang Q, Koeck T, Derecka M, Szczepanek K, Szelag M, Gornicka A, Moh A, Moghaddas S, Chen Q, Bobbili S, Cichy J, ... ... Larner AC, et al. Function of mitochondrial Stat3 in cellular respiration. Science (New York, N.Y.). 323: 793-7. PMID 19131594 DOI: 10.1126/Science.1164551  0.78
2009 Szelag M, Potla R, Sisler J, Hamed H, Dent P, Larner AC. STAT1 Expression represses the expression of mitochondrial encoded RNAS Cytokine. 48: 123-124. DOI: 10.1016/J.Cyto.2009.07.522  0.385
2006 Potla R, Koeck T, Wegrzyn J, Cherukuri S, Shimoda K, Baker DP, Wolfman J, Planchon SM, Esposito C, Hoit B, Dulak J, Wolfman A, Stuehr D, Larner AC. Tyk2 tyrosine kinase expression is required for the maintenance of mitochondrial respiration in primary pro-B lymphocytes Molecular and Cellular Biology. 26: 8562-8571. PMID 16982690 DOI: 10.1128/Mcb.00497-06  0.782
2006 Gamero AM, Potla R, Wegrzyn J, Szelag M, Edling AE, Shimoda K, Link DC, Dulak J, Baker DP, Tanabe Y, Grayson JM, Larner AC. Activation of Tyk2 and Stat3 is required for the apoptotic actions of interferon-beta in primary pro-B cells. The Journal of Biological Chemistry. 281: 16238-44. PMID 16601124 DOI: 10.1074/Jbc.M509516200  0.771
2006 Gamero AM, Potla R, Sakamoto S, Baker DP, Abraham R, Larner AC. Type I interferons activate apoptosis in a Jurkat cell variant by caspase-dependent and independent mechanisms. Cellular Signalling. 18: 1299-308. PMID 16337360 DOI: 10.1016/J.Cellsig.2005.10.008  0.759
2004 Sakamoto S, Potla R, Larner AC. Histone deacetylase activity is required to recruit RNA polymerase II to the promoters of selected interferon-stimulated early response genes. The Journal of Biological Chemistry. 279: 40362-7. PMID 15194680 DOI: 10.1074/Jbc.M406400200  0.767
2004 Gamero AM, Sakamoto S, Montenegro J, Larner AC. Identification of a novel conserved motif in the STAT family that is required for tyrosine phosphorylation. The Journal of Biological Chemistry. 279: 12379-85. PMID 14722125 DOI: 10.1074/Jbc.M310787200  0.592
2004 Sakamoto S, Qin J, Navarro A, Gamero A, Potla R, Yi T, Zhu W, Baker DP, Feldman G, Larner AC. Cells previously desensitized to type 1 interferons display different mechanisms of activation of stat-dependent gene expression from naïve cells. The Journal of Biological Chemistry. 279: 3245-53. PMID 14600148 DOI: 10.1074/Jbc.M309631200  0.794
2003 Navarro A, Frevel M, Gamero AM, Williams BR, Feldman G, Larner AC. Thrombomodulin RNA is destabilized through its 3'-untranslated element in cells exposed to IFN-gamma. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 23: 723-8. PMID 14769148 DOI: 10.1089/107999003772084833  0.425
2003 Navarro A, Anand-Apte B, Tanabe Y, Feldman G, Larner AC. A PI-3 kinase-dependent, Stat1-independent signaling pathway regulates interferon-stimulated monocyte adhesion. Journal of Leukocyte Biology. 73: 540-5. PMID 12660229 DOI: 10.1189/Jlb.1002508  0.532
2002 Yu CY, Wang L, Khaletskiy A, Farrar WL, Larner A, Colburn NH, Li JJ. STAT3 activation is required for interleukin-6 induced transformation in tumor-promotion sensitive mouse skin epithelial cells. Oncogene. 21: 3949-60. PMID 12037677 DOI: 10.1038/Sj.Onc.1205499  0.519
2001 Dong F, Qiu Y, Yi T, Touw IP, Larner AC. The Carboxyl Terminus of the Granulocyte Colony- Stimulating Factor Receptor, Truncated in Patients with Severe Congenital Neutropenia/Acute Myeloid Leukemia, Is Required for SH2-Containing Phosphatase-1 Suppression of Stat Activation Journal of Immunology. 167: 6447-6452. PMID 11714811 DOI: 10.4049/Jimmunol.167.11.6447  0.43
2001 Dong F, Gutkind JS, Larner AC. Granulocyte colony-stimulating factor induces ERK5 activation, which is differentially regulated by protein-tyrosine kinases and protein kinase C. Regulation of cell proliferation and survival. Journal of Biological Chemistry. 276: 10811-10816. PMID 11278431 DOI: 10.1074/Jbc.M008748200  0.45
2001 Gamero AM, Larner AC. Vanadate Facilitates Interferon α-mediated Apoptosis That Is Dependent on the Jak/Stat Pathway Journal of Biological Chemistry. 276: 13547-13553. PMID 11278370 DOI: 10.1074/Jbc.M007948200  0.452
2000 Gamero AM, Larner AC. Signaling via the T cell antigen receptor induces phosphorylation of Stat1 on Serine 727 Journal of Biological Chemistry. 275: 16574-16578. PMID 10748192 DOI: 10.1074/Jbc.M910149199  0.463
2000 Wojnowski L, Stancato LF, Larner AC, Rapp UR, Zimmer A. Overlapping and specific functions of Braf and Craf-1 proto-oncogenes during mouse embryogenesis. Mechanisms of Development. 91: 97-104. PMID 10704835 DOI: 10.1016/S0925-4773(99)00276-2  0.413
2000 Dong F, Larner AC. Activation of Akt kinase by granulocyte colony-stimulating factor (G-CSF): evidence for the role of a tyrosine kinase activity distinct from the Janus kinases. Blood. 95: 1656-1662. DOI: 10.1182/Blood.V95.5.1656.005K29_1656_1662  0.463
1999 Yamashita H, Xu J, Erwin RA, Larner AC, Rui H. A lymphoma growth inhibitor blocks some but not all prolactin-stimulated signaling pathways. The Journal of Biological Chemistry. 274: 14699-705. PMID 10329665 DOI: 10.1074/Jbc.274.21.14699  0.436
1999 Ito S, Ansari P, Sakatsume M, Dickensheets H, Vazquez N, Donnelly RP, Larner AC, Finbloom DS. Interleukin-10 Inhibits Expression of Both Interferon – and Interferon γ– Induced Genes by Suppressing Tyrosine Phosphorylation of STAT1 Blood. 93: 1456-1463. DOI: 10.1182/Blood.V93.5.1456.404A34_1456_1463  0.492
1998 Wojnowski L, Stancato LF, Zimmer AM, Hahn H, Beck TW, Larner AC, Rapp UR, Zimmer A. Craf-1 protein kinase is essential for mouse development Mechanisms of Development. 76: 141-149. PMID 9767153 DOI: 10.1016/S0925-4773(98)00111-7  0.407
1998 Stancato LF, Yu CR, Petricoin EF, Larner AC. Activation of Raf-1 by interferon gamma and oncostatin M requires expression of the Stat1 transcription factor. The Journal of Biological Chemistry. 273: 18701-4. PMID 9668040 DOI: 10.1074/Jbc.273.30.18701  0.564
1998 Wei S, Gamero AM, Liu JH, Daulton AA, Valkov NI, Trapani JA, Larner AC, Weber MJ, Djeu JY. Control of lytic function by mitogen-activated protein kinase/extracellular regulatory kinase 2 (ERK2) in a human natural killer cell line: identification of perforin and granzyme B mobilization by functional ERK2. The Journal of Experimental Medicine. 187: 1753-65. PMID 9607917 DOI: 10.1084/Jem.187.11.1753  0.458
1998 Sakatsume M, Stancato LF, David M, Silvennoinen O, Saharinen P, Pierce J, Larner AC, Finbloom DS. Interferonγ Activation of Raf-1 Is Jak1-dependent and p21ras-independent Journal of Biological Chemistry. 273: 3021-3026. PMID 9446616 DOI: 10.1074/Jbc.273.5.3021  0.508
1997 Stancato LF, Sakatsume M, David M, Dent P, Dong F, Petricoin EF, Krolewski JJ, Silvennoinen O, Saharinen P, Pierce J, Marshall CJ, Sturgill T, Finbloom DS, Larner AC. Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway. Molecular and Cellular Biology. 17: 3833-3840. PMID 9199317 DOI: 10.1128/Mcb.17.7.3833  0.573
1997 Kirken RA, Malabarba MG, Xu J, Liu X, Farrar WL, Hennighausen L, Larner AC, Grimley PM, Rui H. Prolactin stimulates serine/tyrosine phosphorylation and formation of heterocomplexes of multiple Stat5 isoforms in Nb2 lymphocytes. The Journal of Biological Chemistry. 272: 14098-103. PMID 9162035 DOI: 10.1074/Jbc.272.22.14098  0.562
1997 Hackett RH, Wang Y, Sweitzer S, Feldman G, Wood WI, Larner AC. Mapping of a Cytoplasmic Domain of the Human Growth Hormone Receptor That Regulates Rates of Inactivation of Jak2 and Stat Proteins Journal of Biological Chemistry. 272: 11128-11132. PMID 9111009 DOI: 10.1074/Jbc.272.17.11128  0.443
1997 Sharf R, Meraro D, Azriel A, Thornton AM, Ozato K, Petricoin EF, Larner AC, Schaper F, Hauser H, Levi BZ. Phosphorylation events modulate the ability of interferon consensus sequence binding protein to interact with interferon regulatory factors and to bind DNA. The Journal of Biological Chemistry. 272: 9785-92. PMID 9092512 DOI: 10.1074/Jbc.272.15.9785  0.493
1997 DaSilva L, Rui H, Erwin RA, Howard OM, Kirken RA, Malabarba MG, Hackett RH, Larner AC, Farrar WL. Prolactin recruits STAT1, STAT3 and STAT5 independent of conserved receptor tyrosines TYR402, TYR479, TYR515 and TYR580. Molecular and Cellular Endocrinology. 117: 131-40. PMID 8737372 DOI: 10.1016/0303-7207(95)03738-1  0.46
1996 Larner A, Reich NC. Interferon signal transduction Biotherapy. 8: 175-181. PMID 8813329 DOI: 10.1007/Bf01877202  0.484
1996 David M, Zhou G, Pine R, Dixon JE, Larner AC. The SH2 domain-containing tyrosine phosphatase PTP1D is required for interferon α/β-induced gene expression Journal of Biological Chemistry. 271: 15862-15865. PMID 8663536 DOI: 10.1074/Jbc.271.27.15862  0.483
1996 Stancato LF, David M, Carter-Su C, Larner AC, Pratt WB. Preassociation of STAT1 with STAT2 and STAT3 in separate signalling complexes prior to cytokine stimulation Journal of Biological Chemistry. 271: 4134-4137. PMID 8626752 DOI: 10.1074/Jbc.271.8.4134  0.52
1996 David M, Wong L, Flavell R, Thompson SA, Wells A, Larner AC, Johnson GR. STAT activation by epidermal growth factor (EGF) and amphiregulin. Requirement for the EGF receptor kinase but not for tyrosine phosphorylation sites or JAK1. The Journal of Biological Chemistry. 271: 9185-8. PMID 8621573 DOI: 10.1074/Jbc.271.16.9185  0.465
1996 David M, Petricoin E, Larner AC. Activation of Protein Kinase A Inhibits Interferon Induction of the Jak/Stat Pathway in U266 Cells Journal of Biological Chemistry. 271: 4585-4588. PMID 8617715 DOI: 10.1074/Jbc.271.9.4585  0.571
1995 Finbloom DS, Larner AC. Regulation of the Jak/STAT signalling pathway. Cellular Signalling. 7: 739-745. PMID 8593242 DOI: 10.1016/0898-6568(95)02004-7  0.368
1995 David M, Chen HE, Goelz S, Larner AC, Neel BG. Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1 Molecular and Cellular Biology. 15: 7050-7058. PMID 8524272 DOI: 10.1128/Mcb.15.12.7050  0.538
1995 Hackett RH, Wang Y, Larner AC. Mapping of the Cytoplasmic Domain of the Human Growth Hormone Receptor Required for the Activation of Jak2 and Stat Proteins Journal of Biological Chemistry. 270: 21326-21330. PMID 7673169 DOI: 10.1074/Jbc.270.36.21326  0.451
1995 Bacon CM, Petricoin EF, Ortaldo JR, Rees RC, Larner AC, Johnston JA, O'Shea JJ. Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 92: 7307-11. PMID 7638186 DOI: 10.1073/Pnas.92.16.7307  0.482
1995 Sweitzer SM, Calvo S, Kraus MH, Finbloom DS, Larner AC. Characterization of a Stat-like DNA Binding Activity in Drosophila melanogaster Journal of Biological Chemistry. 270: 16510-16513. PMID 7622453 DOI: 10.1074/Jbc.270.28.16510  0.487
1995 Sakatsume M, Igarashi K, Winestock KD, Garotta G, Larner AC, Finbloom DS. The Jak kinases differentially associate with the alpha and beta (accessory factor) chains of the interferon gamma receptor to form a functional receptor unit capable of activating STAT transcription factors. Journal of Biological Chemistry. 270: 17528-17534. PMID 7615558 DOI: 10.1074/Jbc.270.29.17528  0.476
1995 David M, Petricoin E, Benjamin C, Pine R, Weber MJ, Larner AC. Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins. Science (New York, N.Y.). 269: 1721-3. PMID 7569900 DOI: 10.1126/Science.7569900  0.504
1995 Finbloom DS, Larner AC. Induction of early response genes by interferons, interleukins, and growth factors by the tyrosine phosphorylation of latent transcription factors : implications for chronic inflammatory diseases Arthritis & Rheumatism. 38: 877-889. PMID 7541992 DOI: 10.1002/Art.1780380702  0.388
1995 Yu CL, Meyer DJ, Campbell GS, Larner AC, Carter-Su C, Schwartz J, Jove R. Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science (New York, N.Y.). 269: 81-3. PMID 7541555 DOI: 10.1126/Science.7541555  0.515
1995 Larner AC, Finbloom DS. Protein tyrosine phosphorylation as a mechanism which regulates cytokine activation of early response genes. Biochimica Et Biophysica Acta. 1266: 278-287. PMID 7539296 DOI: 10.1016/0167-4889(95)00015-K  0.523
1994 Petricoin E, David M, Fang H, Grimley P, Larner AC, Pol SV. Human cancer cell lines express a negative transcriptional regulator of the interferon regulatory factor family of DNA binding proteins. Molecular and Cellular Biology. 14: 1477-1486. PMID 8289823 DOI: 10.1128/Mcb.14.2.1477  0.465
1994 David M, Petricoin EF, Igarashi K-, Feldman GM, Finbloom DS, Larner AC. Prolactin activates the interferon-regulated p91 transcription factor and the Jak2 kinase by tyrosine phosphorylation Proceedings of the National Academy of Sciences of the United States of America. 91: 7174-7178. PMID 7518927 DOI: 10.1073/Pnas.91.15.7174  0.558
1993 Larner AC, David M, Feldman GM, Igarashi K, Hackett RH, Webb DSA, Sweitzer SM, Petricoin EF, Finbloom DS. Tyrosine phosphorylation of DNA binding proteins by multiple cytokines Science. 261: 1730-1733. PMID 8378773 DOI: 10.1126/Science.8378773  0.467
1993 Igarashi K-, David M, Larner AC, Finbloom DS. In vitro activation of a transcription factor by gamma interferon requires a membrane-associated tyrosine kinase and is mimicked by vanadate. Molecular and Cellular Biology. 13: 3984-3989. PMID 8321205 DOI: 10.1128/Mcb.13.7.3984  0.462
1993 David M, Grimley PM, Finbloom DS, Larner AC. A nuclear tyrosine phosphatase downregulates interferon-induced gene expression. Molecular and Cellular Biology. 13: 7515-7521. PMID 8246969 DOI: 10.1128/Mcb.13.12.7515  0.533
1993 Igarashi K, David M, Finbloom DS, Larner AC. In vitro activation of the transcription factor gamma interferon activation factor by gamma interferon: evidence for a tyrosine phosphatase/kinase signaling cascade. Molecular and Cellular Biology. 13: 1634-1640. PMID 7680098 DOI: 10.1128/Mcb.13.3.1634  0.495
1992 Nakagawa Y, Petricoin EF, Akai H, Grimley PM, Rupp B, Larner AC. Interferon-alpha-induced gene expression: evidence for a selective effect of ouabain on activation of the ISGF3 transcription complex. Virology. 190: 210-220. PMID 1529530 DOI: 10.1016/0042-6822(92)91207-B  0.513
1992 David M, Larner AC. Activation of transcription factors by interferon-alpha in a cell-free system. Science. 257: 813-815. PMID 1496402 DOI: 10.1126/Science.1496402  0.426
1992 Petricoin EF, Hackett RH, Akai H, Igarashi K, Finbloom DS, Larner AC. Modulation of interferon signaling in human fibroblasts by phorbol esters. Molecular and Cellular Biology. 12: 4486-4495. PMID 1406637 DOI: 10.1128/Mcb.12.10.4486  0.458
1988 Sato T, Larner J, Larner AC. Selective transcription of an insulin-regulated gene in nuclear extracts of rat hepatoma cells. Biochemical and Biophysical Research Communications. 153: 116-127. PMID 3288202 DOI: 10.1016/S0006-291X(88)81197-5  0.35
1988 Sato T, Ye T, Larner A, Larner J. Contrasting interactions between phorbol ester and insulin on the regulation of glycogen synthase activity and p33 mRNA accumulation in rat hepatoma cells Archives of Biochemistry and Biophysics. 260: 377-387. PMID 3124751 DOI: 10.1016/0003-9861(88)90461-4  0.357
1988 Sato T, Palasi CV, Huang L, Tang G, Larner AC, Larner J. Insulin and a putative insulin metabolic mediator fraction from liver and muscle stimulate p33 Messenger ribonucleic acid accumulation by apparently different mechanisms Endocrinology. 123: 1559-1564. PMID 3042371 DOI: 10.1210/Endo-123-3-1559  0.311
1988 Akai H, Larner AC. Mapping of a DNA sequence that down-regulates the expression of an interferon-induced gene. Biochemical and Biophysical Research Communications. 156: 701-705. PMID 2461196 DOI: 10.1016/S0006-291X(88)80899-4  0.478
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