| Year |
Citation |
Score |
| 2023 |
Wallabregue ALD, Bolland H, Faulkner S, Hammond EM, Conway SJ. Two Color Imaging of Different Hypoxia Levels in Cancer Cells. Journal of the American Chemical Society. 145: 2572-2583. PMID 36656915 DOI: 10.1021/jacs.2c12493 |
0.563 |
|
| 2022 |
Koyasu S, Horita S, Saito K, Kobayashi M, Ishikita H, Chow CC, Kambe G, Nishikawa S, Menju T, Morinibu A, Okochi Y, Tabuchi Y, Onodera Y, Takeda N, Date H, ... ... Hammond EM, et al. ZBTB2 links p53 deficiency to HIF-1-mediated hypoxia signaling to promote cancer aggressiveness. Embo Reports. e202154042. PMID 36341521 DOI: 10.15252/embr.202154042 |
0.399 |
|
| 2022 |
Sekirnik AR, Reynolds JK, See L, Bluck JP, Scorah AR, Tallant C, Lee B, Leszczynska KB, Grimley RL, Storer RI, Malattia M, Crespillo S, Caria S, Duclos S, Hammond EM, et al. Identification of Histone Peptide Binding Specificity and Small-Molecule Ligands for the TRIM33α and TRIM33β Bromodomains. Acs Chemical Biology. PMID 36098557 DOI: 10.1021/acschembio.2c00266 |
0.52 |
|
| 2021 |
Suwa T, Kobayashi M, Shirai Y, Nam JM, Tabuchi Y, Takeda N, Akamatsu S, Ogawa O, Mizowaki T, Hammond EM, Harada H. SPINK1 as a plasma marker for tumor hypoxia and a therapeutic target for radiosensitization. Jci Insight. 6. PMID 34747365 DOI: 10.1172/jci.insight.148135 |
0.396 |
|
| 2021 |
Troelsen KS, Calder EDD, Skwarska A, Sneddon D, Hammond EM, Conway SJ. Zap-Pano: a Photocaged pro-drug of the KDAC inhibitor panobinostat. Chemmedchem. PMID 34259396 DOI: 10.1002/cmdc.202100403 |
0.54 |
|
| 2021 |
Brand M, Clayton J, Moroglu M, Schiedel M, Picaud S, Bluck JP, Skwarska A, Bolland H, Chan AKN, Laurin CMC, Scorah AR, See L, Rooney TPC, Andrews KH, Fedorov O, ... ... Hammond EM, et al. Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain. Journal of Medicinal Chemistry. PMID 34255515 DOI: 10.1021/acs.jmedchem.1c00348 |
0.655 |
|
| 2021 |
Bader SB, Ma TS, Simpson CJ, Liang J, Maezono SEB, Olcina MM, Buffa FM, Hammond EM. Replication catastrophe induced by cyclic hypoxia leads to increased APOBEC3B activity. Nucleic Acids Research. PMID 34197599 DOI: 10.1093/nar/gkab551 |
0.688 |
|
| 2021 |
Ramachandran S, Ma TS, Griffin J, Ng N, Foskolou IP, Hwang MS, Victori P, Cheng WC, Buffa FM, Leszczynska KB, El-Khamisy SF, Gromak N, Hammond EM. Hypoxia-induced SETX links replication stress with the unfolded protein response. Nature Communications. 12: 3686. PMID 34140498 DOI: 10.1038/s41467-021-24066-z |
0.481 |
|
| 2021 |
Skwarska A, Calder EDD, Sneddon D, Bolland H, Odyniec ML, Mistry IN, Martin J, Folkes LK, Conway SJ, Hammond EM. Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor. Cell Chemical Biology. PMID 33910023 DOI: 10.1016/j.chembiol.2021.04.004 |
0.524 |
|
| 2020 |
Bowler E, Skwarska A, Wilson JD, Ramachandran S, Bolland H, Easton A, Ostheimer C, Hwang MS, Leszczynska KB, Conway SJ, Hammond EM. Pharmacological Inhibition of ATR Can Block Autophagy through an ATR-Independent Mechanism. Iscience. 23: 101668. PMID 33134898 DOI: 10.1016/j.isci.2020.101668 |
0.578 |
|
| 2018 |
Collins SL, Saha J, Bouchez LC, Hammond EM, Conway SJ. Hypoxia-activated small molecule-induced gene expression. Acs Chemical Biology. PMID 30451487 DOI: 10.1021/Acschembio.8B00858 |
0.565 |
|
| 2018 |
Carruthers RD, Ahmed SU, Ramachandran S, Strathdee K, Kurian KM, Hedley A, Gomez-Roman N, Kalna G, Neilson MP, Gilmour L, Stevenson KH, Hammond EM, Chalmers AJ. Replication stress drives constitutive activation of the DNA damage response and radioresistance in glioblastoma stem-like cells. Cancer Research. PMID 29976574 DOI: 10.1158/0008-5472.CAN-18-0569 |
0.424 |
|
| 2018 |
Jennings LE, Schiedel M, Hewings DS, Picaud S, Laurin CMC, Bruno PA, Bluck JP, Scorah AR, See L, Reynolds JK, Moroglu M, Mistry IN, Hicks A, Guzanov P, Clayton J, ... ... Hammond EM, et al. BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability. Bioorganic & Medicinal Chemistry. PMID 29776834 DOI: 10.1016/J.Bmc.2018.05.003 |
0.465 |
|
| 2018 |
Poujade FA, Mannion A, Brittain N, Theodosi A, Beeby E, Leszczynska KB, Hammond EM, Greenman J, Cawthorne C, Pires IM. WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer. British Journal of Cancer. PMID 29540773 DOI: 10.1038/s41416-018-0056-3 |
0.532 |
|
| 2017 |
Ng N, Purshouse K, Foskolou IP, Olcina MM, Hammond EM. Challenges to DNA replication in hypoxic conditions. The Febs Journal. PMID 29288533 DOI: 10.1111/febs.14377 |
0.688 |
|
| 2017 |
Mistry IN, Thomas M, Calder EDD, Conway SJ, Hammond EM. Clinical Advances of Hypoxia-Activated Prodrugs in Combination With Radiation Therapy. International Journal of Radiation Oncology, Biology, Physics. 98: 1183-1196. PMID 28721903 DOI: 10.1016/J.Ijrobp.2017.03.024 |
0.538 |
|
| 2017 |
Foskolou IP, Jorgensen C, Leszczynska KB, Olcina MM, Tarhonskaya H, Haisma B, D'Angiolella V, Myers WK, Domene C, Flashman E, Hammond EM. Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication. Molecular Cell. PMID 28416140 DOI: 10.1016/j.molcel.2017.03.005 |
0.773 |
|
| 2017 |
O'Connor LJ, Mistry IN, Collins SL, Folkes LK, Brown G, Conway SJ, Hammond EM. CYP450 Enzymes Effect Oxygen-Dependent Reduction of Azide-Based Fluorogenic Dyes. Acs Central Science. 3: 20-30. PMID 28149949 DOI: 10.1021/Acscentsci.6B00276 |
0.513 |
|
| 2016 |
Olcina MM, Giaccia AJ, Hammond EM. Isolation of Proteins on Nascent DNA in Hypoxia and Reoxygenation Conditions. Advances in Experimental Medicine and Biology. 899: 27-40. PMID 27325260 DOI: 10.1007/978-3-319-26666-4_3 |
0.77 |
|
| 2016 |
Foskolou IP, Biasoli D, Olcina MM, Hammond EM. Measuring DNA Replication in Hypoxic Conditions. Advances in Experimental Medicine and Biology. 899: 11-25. PMID 27325259 DOI: 10.1007/978-3-319-26666-4_2 |
0.751 |
|
| 2016 |
O'Connor LJ, Cazares-Körner C, Saha J, Evans CN, Stratford MR, Hammond EM, Conway SJ. Design, synthesis and evaluation of molecularly targeted hypoxia-activated prodrugs. Nature Protocols. 11: 781-94. PMID 27010756 DOI: 10.1038/Nprot.2016.034 |
0.51 |
|
| 2016 |
Leszczynska KB, Göttgens EL, Biasoli D, Olcina MM, Ient J, Anbalagan S, Bernhardt S, Giaccia AJ, Hammond EM. Mechanisms and consequences of ATMIN repression in hypoxic conditions: roles for p53 and HIF-1. Scientific Reports. 6: 21698. PMID 26875667 DOI: 10.1038/Srep21698 |
0.783 |
|
| 2015 |
Leszczynska KB, Foskolou IP, Abraham AG, Anbalagan S, Tellier C, Haider S, Span PN, O'Neill EE, Buffa FM, Hammond EM. Hypoxia-induced p53 modulates both apoptosis and radiosensitivity via AKT. The Journal of Clinical Investigation. 125: 2385-98. PMID 25961455 DOI: 10.1172/JCI80402 |
0.319 |
|
| 2015 |
Pefani DE, Latusek R, Pires I, Grawenda AM, Yee KS, Hamilton G, van der Weyden L, Esashi F, Hammond EM, O'Neill E. RASSF1A-LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2. Nature Cell Biology. 17: 531. PMID 25812526 DOI: 10.1038/ncb3152 |
0.563 |
|
| 2014 |
Olcina MM, Grand RJ, Hammond EM. ATM activation in hypoxia - causes and consequences. Molecular & Cellular Oncology. 1: e29903. PMID 27308313 DOI: 10.4161/mco.29903 |
0.793 |
|
| 2014 |
Pefani DE, Latusek R, Pires I, Grawenda AM, Yee KS, Hamilton G, Van Der Weyden L, Esashi F, Hammond EM, O'Neill E. RASSF1A-LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2 Nature Cell Biology. 16: 962-971. PMID 25218637 DOI: 10.1038/ncb3035 |
0.61 |
|
| 2014 |
Pires IM, Blokland NJ, Broos AW, Poujade FA, Senra JM, Eccles SA, Span PN, Harvey AJ, Hammond EM. HIF-1α-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion. Cancer Biology & Therapy. 15: 1350-7. PMID 25019382 DOI: 10.4161/cbt.29822 |
0.567 |
|
| 2014 |
Koumenis C, Hammond E, Giaccia A. Tumor microenvironment and cellular stress: signaling, metabolism, imaging, and therapeutic targets. Preface. Advances in Experimental Medicine and Biology. 772: v-viii. PMID 24765667 DOI: 10.1007/978-1-4614-5915-6 |
0.48 |
|
| 2014 |
Olcina MM, Hammond EM. WIP1 and senescence: oxygen matters. Cell Cycle (Georgetown, Tex.). 13: 1062. PMID 24584094 DOI: 10.4161/cc.28385 |
0.688 |
|
| 2014 |
Scrace S, O'Neill E, Hammond EM, Pires IM. Use of the xCELLigence system for real-time analysis of changes in cellular motility and adhesion in physiological conditions. Methods in Molecular Biology (Clifton, N.J.). 1046: 295-306. PMID 23868595 DOI: 10.1007/978-1-62703-538-5_17 |
0.534 |
|
| 2014 |
Fokas E, Prevo R, Hammond EM, Brunner TB, McKenna WG, Muschel RJ. Targeting ATR in DNA damage response and cancer therapeutics. Cancer Treatment Reviews. 40: 109-17. PMID 23583268 DOI: 10.1016/j.ctrv.2013.03.002 |
0.412 |
|
| 2013 |
Olcina MM, Foskolou IP, Anbalagan S, Senra JM, Pires IM, Jiang Y, Ryan AJ, Hammond EM. Replication stress and chromatin context link ATM activation to a role in DNA replication Molecular Cell. 52: 758-766. PMID 24268576 DOI: 10.1016/j.molcel.2013.10.019 |
0.801 |
|
| 2013 |
Cazares-Körner C, Pires IM, Swallow ID, Grayer SC, O'Connor LJ, Olcina MM, Christlieb M, Conway SJ, Hammond EM. CH-01 is a hypoxia-activated prodrug that sensitizes cells to hypoxia/reoxygenation through inhibition of Chk1 and Aurora A. Acs Chemical Biology. 8: 1451-9. PMID 23597309 DOI: 10.1021/cb4001537 |
0.784 |
|
| 2013 |
Hewings DS, Fedorov O, Filippakopoulos P, Martin S, Picaud S, Tumber A, Wells C, Olcina MM, Freeman K, Gill A, Ritchie AJ, Sheppard DW, Russell AJ, Hammond EM, Knapp S, et al. Optimization of 3,5-dimethylisoxazole derivatives as potent bromodomain ligands. Journal of Medicinal Chemistry. 56: 3217-27. PMID 23517011 DOI: 10.1021/Jm301588R |
0.739 |
|
| 2012 |
Anbalagan S, Pires IM, Blick C, Hill MA, Ferguson DJ, Chan DA, Hammond EM. Radiosensitization of renal cell carcinoma in vitro through the induction of autophagy. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 103: 388-93. PMID 22551566 DOI: 10.1016/j.radonc.2012.04.001 |
0.694 |
|
| 2011 |
Pires IM, Bencokova Z, McGurk C, Hammond EM. Exposure to acute hypoxia induces a transient DNA damage response which includes Chk1 and TLK1. Cell Cycle (Georgetown, Tex.). 9: 2502-7. PMID 20581459 DOI: 10.4161/cc.9.13.12059 |
0.532 |
|
| 2010 |
Chan N, Pires IM, Bencokova Z, Coackley C, Luoto KR, Bhogal N, Lakshman M, Gottipati P, Oliver FJ, Helleday T, Hammond EM, Bristow RG. Contextual synthetic lethality of cancer cell kill based on the tumor microenvironment. Cancer Research. 70: 8045-54. PMID 20924112 DOI: 10.1158/0008-5472.Can-10-2352 |
0.644 |
|
| 2010 |
Olcina M, Lecane PS, Hammond EM. Targeting hypoxic cells through the DNA damage response. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 5624-9. PMID 20876254 DOI: 10.1158/1078-0432.CCR-10-0286 |
0.688 |
|
| 2010 |
Pires IM, Bencokova Z, Milani M, Folkes LK, Li JL, Stratford MR, Harris AL, Hammond EM. Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability. Cancer Research. 70: 925-35. PMID 20103649 DOI: 10.1158/0008-5472.CAN-09-2715 |
0.661 |
|
| 2009 |
Rankin EB, Giaccia AJ, Hammond EM. Bringing H2AX into the angiogenesis family. Cancer Cell. 15: 459-61. PMID 19477424 DOI: 10.1016/J.Ccr.2009.05.004 |
0.523 |
|
| 2009 |
Bencokova Z, Kaufmann MR, Pires IM, Lecane PS, Giaccia AJ, Hammond EM. ATM activation and signaling under hypoxic conditions. Molecular and Cellular Biology. 29: 526-37. PMID 18981219 DOI: 10.1128/Mcb.01301-08 |
0.732 |
|
| 2007 |
Hammond EM, Kaufmann MR, Giaccia AJ. Oxygen sensing and the DNA-damage response. Current Opinion in Cell Biology. 19: 680-4. PMID 18023567 DOI: 10.1016/J.Ceb.2007.10.002 |
0.518 |
|
| 2006 |
Krieg AJ, Hammond EM, Giaccia AJ. Functional analysis of p53 binding under differential stresses. Molecular and Cellular Biology. 26: 7030-45. PMID 16980608 DOI: 10.1128/Mcb.00322-06 |
0.509 |
|
| 2006 |
Hammond EM, Giaccia AJ. Hypoxia-inducible factor-1 and p53: friends, acquaintances, or strangers? Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5007-9. PMID 16951213 DOI: 10.1158/1078-0432.Ccr-06-0613 |
0.436 |
|
| 2006 |
Freiberg RA, Krieg AJ, Giaccia AJ, Hammond EM. Checking in on hypoxia/reoxygenation. Cell Cycle (Georgetown, Tex.). 5: 1304-7. PMID 16760660 DOI: 10.4161/Cc.5.12.2811 |
0.772 |
|
| 2006 |
Hammond EM, Mandell DJ, Salim A, Krieg AJ, Johnson TM, Shirazi HA, Attardi LD, Giaccia AJ. Genome-wide analysis of p53 under hypoxic conditions Molecular and Cellular Biology. 26: 3492-3504. PMID 16611991 DOI: 10.1128/Mcb.26.9.3492-3504.2006 |
0.545 |
|
| 2006 |
Freiberg RA, Hammond EM, Dorie MJ, Welford SM, Giaccia AJ. DNA damage during reoxygenation elicits a Chk2-dependent checkpoint response. Molecular and Cellular Biology. 26: 1598-609. PMID 16478982 DOI: 10.1128/Mcb.26.5.1598-1609.2006 |
0.769 |
|
| 2006 |
Hammond EM, Freiberg RA, Giaccia AJ. The roles of Chk 1 and Chk 2 in hypoxia and reoxygenation. Cancer Letters. 238: 161-7. PMID 16085356 DOI: 10.1016/J.Canlet.2005.06.029 |
0.75 |
|
| 2005 |
Hammond EM, Giaccia AJ. The role of p53 in hypoxia-induced apoptosis. Biochemical and Biophysical Research Communications. 331: 718-25. PMID 15865928 DOI: 10.1016/J.Bbrc.2005.03.154 |
0.547 |
|
| 2005 |
Johnson TM, Hammond EM, Giaccia A, Attardi LD. The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality Nature Genetics. 37: 145-152. PMID 15654339 DOI: 10.1038/Ng1498 |
0.52 |
|
| 2004 |
Hammond EM, Dorie MJ, Giaccia AJ. Inhibition of ATR leads to increased sensitivity to hypoxia/reoxygenation. Cancer Research. 64: 6556-62. PMID 15374968 DOI: 10.1158/0008-5472.Can-04-1520 |
0.58 |
|
| 2004 |
Romero-Ramirez L, Cao H, Nelson D, Hammond E, Lee AH, Yoshida H, Mori K, Glimcher LH, Denko NC, Giaccia AJ, Le QT, Koong AC. XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. Cancer Research. 64: 5943-7. PMID 15342372 DOI: 10.1158/0008-5472.Can-04-1606 |
0.609 |
|
| 2004 |
Hammond EM, Giaccia AJ. The role of ATM and ATR in the cellular response to hypoxia and re-oxygenation. Dna Repair. 3: 1117-22. PMID 15279800 DOI: 10.1016/J.Dnarep.2004.03.035 |
0.59 |
|
| 2003 |
Hammond EM, Green SL, Giaccia AJ. Comparison of hypoxia-induced replication arrest with hydroxyurea and aphidicolin-induced arrest. Mutation Research. 532: 205-13. PMID 14643437 DOI: 10.1016/J.Mrfmmm.2003.08.017 |
0.722 |
|
| 2003 |
Hammond EM, Dorie MJ, Giaccia AJ. ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation. The Journal of Biological Chemistry. 278: 12207-13. PMID 12519769 DOI: 10.1074/Jbc.M212360200 |
0.586 |
|
| 2002 |
Hammond EM, Giaccia AJ. Antiangiogenic therapy and p53. Science (New York, N.Y.). 297: 471; discussion 471. PMID 12142499 DOI: 10.1126/Science.297.5581.471A |
0.383 |
|
| 2002 |
Hammond EM, Denko NC, Dorie MJ, Abraham RT, Giaccia AJ. Hypoxia links ATR and p53 through replication arrest. Molecular and Cellular Biology. 22: 1834-43. PMID 11865061 DOI: 10.1128/Mcb.22.6.1834-1843.2002 |
0.571 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2011 |
Thalhammer A, Bencokova Z, Poole R, Loenarz C, Adam J, O'Flaherty L, Schödel J, Mole D, Giaslakiotis K, Schofield CJ, Hammond EM, Ratcliffe PJ, Pollard PJ. Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α). Plos One. 6: e16210. PMID 21264265 DOI: 10.1371/Journal.Pone.0016210 |
0.29 |
|
| 2023 |
Rodriguez-Berriguete G, Ranzani M, Prevo R, Puliyadi R, Machado N, Bolland HR, Millar V, Ebner D, Boursier M, Cerutti A, Cicconi A, Galbiati A, Grande D, Grinkevich V, Majithiya J, ... ... Hammond EM, et al. Small-molecule Polθ inhibitors provide safe and effective tumor radiosensitization in preclinical models. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 36689546 DOI: 10.1158/1078-0432.CCR-22-2977 |
0.285 |
|
| 2017 |
Nakashima R, Goto Y, Koyasu S, Kobayashi M, Morinibu A, Yoshimura M, Hiraoka M, Hammond EM, Harada H. UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization. Scientific Reports. 7: 6879. PMID 28761052 DOI: 10.1038/s41598-017-06605-1 |
0.273 |
|
| 2015 |
Anbalagan S, Biasoli D, Leszczynska KB, Mukherjee S, Hammond EM. In Vitro Radiosensitization of Esophageal Cancer Cells with the Aminopeptidase Inhibitor CHR-2797. Radiation Research. 184: 259-65. PMID 26291737 DOI: 10.1667/RR14150.1 |
0.265 |
|
| 2015 |
Ramachandran S, Ient J, Göttgens EL, Krieg AJ, Hammond EM. Epigenetic Therapy for Solid Tumors: Highlighting the Impact of Tumor Hypoxia. Genes. 6: 935-56. PMID 26426056 DOI: 10.3390/genes6040935 |
0.257 |
|
| 2017 |
Dobrynin G, McAllister TE, Leszczynska KB, Ramachandran S, Krieg AJ, Kawamura A, Hammond EM. KDM4A regulates HIF-1 levels through H3K9me3. Scientific Reports. 7: 11094. PMID 28894274 DOI: 10.1038/S41598-017-11658-3 |
0.239 |
|
| 2022 |
Celora GL, Bader SB, Hammond EM, Maini PK, Pitt-Francis JM, Byrne HM. DNA-structured mathematical model of cell-cycle progression in cyclic hypoxia. Journal of Theoretical Biology. 111104. PMID 35337794 DOI: 10.1016/j.jtbi.2022.111104 |
0.239 |
|
| 2003 |
Denko N, Wernke-Dollries K, Johnson AB, Hammond E, Chiang CM, Barton MC. Hypoxia actively represses transcription by inducing negative cofactor 2 (Dr1/DrAP1) and blocking preinitiation complex assembly. The Journal of Biological Chemistry. 278: 5744-9. PMID 12477712 DOI: 10.1074/Jbc.M212534200 |
0.239 |
|
| 2021 |
Martí JM, Garcia-Diaz A, Delgado-Bellido D, O'Valle F, González-Flores A, Carlevaris O, Rodríguez-Vargas JM, Amé JC, Dantzer F, King GL, Dziedzic K, Berra E, de Álava E, Amaral AT, Hammond EM, et al. Selective modulation by PARP-1 of HIF-1α-recruitment to chromatin during hypoxia is required for tumor adaptation to hypoxic conditions. Redox Biology. 41: 101885. PMID 33581682 DOI: 10.1016/j.redox.2021.101885 |
0.234 |
|
| 2016 |
Yeom CJ, Zeng L, Goto Y, Morinibu A, Zhu Y, Shinomiya K, Kobayashi M, Itasaka S, Yoshimura M, Hur CG, Kakeya H, Hammond EM, Hiraoka M, Harada H. LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis. Oncotarget. PMID 27589564 DOI: 10.18632/oncotarget.11670 |
0.226 |
|
| 2016 |
Ashton TM, Fokas E, Kunz-Schughart LA, Folkes LK, Anbalagan S, Huether M, Kelly CJ, Pirovano G, Buffa FM, Hammond EM, Stratford M, Muschel RJ, Higgins GS, McKenna WG. The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia. Nature Communications. 7: 12308. PMID 27453292 DOI: 10.1038/ncomms12308 |
0.225 |
|
| 2012 |
Phadwal K, Alegre-Abarrategui J, Watson AS, Pike L, Anbalagan S, Hammond EM, Wade-Martins R, McMichael A, Klenerman P, Simon AK. A novel method for autophagy detection in primary cells: Impaired levels of macroautophagy in immunosenescent T cells Autophagy. 8: 677-689. PMID 22302009 DOI: 10.4161/auto.18935 |
0.212 |
|
| 2017 |
Skwarska A, Ramachandran S, Dobrynin G, Leszczynska KB, Hammond EM. The imidazoacridinone C-1311 induces p53-dependent senescence or p53-independent apoptosis and sensitizes cancer cells to radiation. Oncotarget. PMID 28415717 DOI: 10.18632/oncotarget.16102 |
0.21 |
|
| 2014 |
Hammond EM, Muschel RJ. Radiation and ATM inhibition: the heart of the matter. The Journal of Clinical Investigation. 124: 3289-91. PMID 25036714 DOI: 10.1172/JCI77195 |
0.188 |
|
| 2016 |
Jiang Y, Verbiest T, Devery AM, Bokobza SM, Weber AM, Leszczynska KB, Hammond EM, Ryan AJ. Hypoxia Potentiates the Radiation-Sensitizing Effect of Olaparib in Human Non-Small Cell Lung Cancer Xenografts by Contextual Synthetic Lethality. International Journal of Radiation Oncology, Biology, Physics. PMID 27020103 DOI: 10.1016/j.ijrobp.2016.01.035 |
0.171 |
|
| 2021 |
Wing PA, Liu PJ, Harris JM, Magri A, Michler T, Zhuang X, Borrmann H, Minisini R, Frampton NR, Wettengel JM, Mailly L, D'Arienzo V, Riedl T, Nobre L, Weekes MP, ... ... Hammond EM, et al. Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter. Journal of Hepatology. PMID 33516779 DOI: 10.1016/j.jhep.2020.12.034 |
0.17 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Hammond EM, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.169 |
|
| 2017 |
Groselj B, Ruan JL, Scott H, Gorrill J, Nicholson J, Kelly J, Anbalagan S, Thompson J, Stratford MR, Jevons SJ, Hammond EM, Scudamore CL, Kerr M, Kiltie AE. Radiosensitisation in vivo by histone deacetylase inhibition with no increase in early normal tissue radiation toxicity. Molecular Cancer Therapeutics. PMID 28839000 DOI: 10.1158/1535-7163.MCT-17-0011 |
0.159 |
|
| 2016 |
Leszczynska KB, Dobrynin G, Leslie RE, Ient J, Boumelha AJ, Senra JM, Hawkins MA, Maughan T, Mukherjee S, Hammond EM. Preclinical testing of an Atr inhibitor demonstrates improved response to standard therapies for esophageal cancer. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. PMID 27839769 DOI: 10.1016/j.radonc.2016.10.023 |
0.132 |
|
| 2020 |
Göttgens EL, Bussink J, Ansems M, Hammond EM, Span PN. AKT inhibition as a strategy for targeting hypoxic HPV-positive HNSCC. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 149: 1-7. PMID 32361013 DOI: 10.1016/j.radonc.2020.04.048 |
0.127 |
|
| 2022 |
Worth KR, Papandreou I, Hammond EM. How the histological structure of some lung cancers shaped almost 70 years of radiobiology. British Journal of Cancer. 128: 407-412. PMID 36344595 DOI: 10.1038/s41416-022-02041-9 |
0.12 |
|
| 2022 |
Higgins GS, Hammond EM. Elucidating the role of transiently hypoxic tumour cells on radiation resistance. British Journal of Cancer. 126: 971-972. PMID 35197582 DOI: 10.1038/s41416-022-01741-6 |
0.12 |
|
| 2021 |
Bolland H, Ma TS, Ramlee S, Ramadan K, Hammond EM. Links between the unfolded protein response and the DNA damage response in hypoxia: a systematic review. Biochemical Society Transactions. PMID 34003246 DOI: 10.1042/BST20200861 |
0.12 |
|
| 2020 |
Bader SB, Dewhirst MW, Hammond EM. Cyclic Hypoxia: An Update on Its Characteristics, Methods to Measure It and Biological Implications in Cancer. Cancers. 13. PMID 33374581 DOI: 10.3390/cancers13010023 |
0.12 |
|
| 2020 |
Niemira M, Borowa-Mazgaj B, Bader SB, Moszyńska A, Ratajewski M, Karaś K, Kwaśniewski M, Krętowski A, Mazerska Z, Hammond EM, Skwarska A. Anticancer Imidazoacridinone C-1311 is Effective in Androgen-Dependent and Androgen-Independent Prostate Cancer Cells. Biomedicines. 8. PMID 32825120 DOI: 10.3390/biomedicines8090292 |
0.12 |
|
| 2019 |
Wilson JD, Hammond EM, Higgins GS, Petersson K. Ultra-High Dose Rate (FLASH) Radiotherapy: Silver Bullet or Fool's Gold? Frontiers in Oncology. 9: 1563. PMID 32010633 DOI: 10.3389/fonc.2019.01563 |
0.12 |
|
| 2017 |
Foskolou IP, Hammond EM. RRM2B: An oxygen-requiring protein with a role in hypoxia. Molecular & Cellular Oncology. 4: e1335272. PMID 29057303 DOI: 10.1080/23723556.2017.1335272 |
0.12 |
|
| 2016 |
Sayal KK, Higgins GS, Hammond EM. Uncovering the influence of the FGFR1 pathway on glioblastoma radiosensitivity. Annals of Translational Medicine. 4: 538. PMID 28149899 DOI: 10.21037/atm.2016.11.65 |
0.12 |
|
| 2014 |
Carrera S, Senra J, Acosta MI, Althubiti M, Hammond EM, de Verdier PJ, Macip S. The role of the HIF-1α transcription factor in increased cell division at physiological oxygen tensions. Plos One. 9: e97938. PMID 24835245 DOI: 10.1371/journal.pone.0097938 |
0.12 |
|
| 2019 |
Göttgens EL, Bussink J, Leszczynska KB, Peters H, Span PN, Hammond EM. Inhibition of CD4/CDK6 enhances radiosensitivity of HPV negative head and neck squamous cell carcinomas. International Journal of Radiation Oncology, Biology, Physics. PMID 31271827 DOI: 10.1016/j.ijrobp.2019.06.2531 |
0.115 |
|
| 2020 |
Muschel RJ, Hammond EM, Dewhirst MW. A New Assay to Measure Intestinal Crypt Survival after Irradiation: Challenges and Opportunities. Cancer Research. 80: 927-928. PMID 32122905 DOI: 10.1158/0008-5472.CAN-19-4045 |
0.104 |
|
| 2018 |
Göttgens EL, Ostheimer C, Bussink J, Span PN, Hammond E. HPV, hypoxia and radiation response in head and neck cancer. The British Journal of Radiology. 20180047. PMID 29493265 DOI: 10.1259/bjr.20180047 |
0.095 |
|
| 2022 |
Bolland HR, Hammond EM, Sedgwick AC. A fluorescent probe strategy for the detection and discrimination of hydrogen peroxide and peroxynitrite in cells. Chemical Communications (Cambridge, England). 58: 10699-10702. PMID 36069107 DOI: 10.1039/d2cc03406a |
0.083 |
|
| 2015 |
Goto Y, Zeng L, Yeom CJ, Zhu Y, Morinibu A, Shinomiya K, Kobayashi M, Hirota K, Itasaka S, Yoshimura M, Tanimoto K, Torii M, Sowa T, Menju T, Sonobe M, ... ... Hammond EM, et al. UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α. Nature Communications. 6: 6153. PMID 25615526 DOI: 10.1038/ncomms7153 |
0.078 |
|
| 2002 |
Clark K, Hammond E, Rabbitts P. Temporal and spatial expression of two isoforms of the Dutt1/Robo1 gene in mouse development. Febs Letters. 523: 12-6. PMID 12123796 DOI: 10.1016/s0014-5793(02)02904-6 |
0.077 |
|
| 2020 |
Williams K, Jeggo PA, Hammond EM, West C, Badie C, Anderson RM. Meeting report of the 16th international congress of radiation research and the 12th international symposium on chromosomal aberrations. Journal of Radiological Protection : Official Journal of the Society For Radiological Protection. 40: 361-365. PMID 32084014 DOI: 10.1088/1361-6498/Ab52De |
0.076 |
|
| 2019 |
Williams KJ, Hammond EM, West C, Anderson RM, Badie C, Jeggo PA. Meeting Report on ICRR2019, the 16 International Congress on Radiation Research. International Journal of Radiation Biology. 1-12. PMID 31702416 DOI: 10.1080/09553002.2020.1688886 |
0.064 |
|
| 2020 |
Wilson JD, Hammond EM, Higgins GS, Petersson K. Corrigendum: Ultra-High Dose Rate (FLASH) Radiotherapy: Silver Bullet or Fool's Gold? Frontiers in Oncology. 10: 210. PMID 32161721 DOI: 10.3389/fonc.2020.00210 |
0.048 |
|
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