Donald S. Kirkpatrick, Ph.D. - Publications

Affiliations: 
2003 University of Arizona, Tucson, AZ 
Area:
Toxicology

74/117 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Phu L, Rose CM, Tea JS, Wall CE, Verschueren E, Cheung TK, Kirkpatrick DS, Bingol B. Dynamic Regulation of Mitochondrial Import by the Ubiquitin System. Molecular Cell. 77: 1107-1123.e10. PMID 32142684 DOI: 10.1016/J.Molcel.2020.02.012  0.371
2020 Budayeva HG, Kirkpatrick DS. Monitoring protein communities and their responses to therapeutics. Nature Reviews. Drug Discovery. PMID 32139903 DOI: 10.1038/S41573-020-0063-Y  0.367
2020 Vogl AM, Phu L, Becerra R, Giusti SA, Verschueren E, Hinkle TB, Bordenave MD, Adrian M, Heidersbach A, Yankilevich P, Stefani FD, Wurst W, Hoogenraad CC, Kirkpatrick DS, Refojo D, et al. Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics. Nature Structural & Molecular Biology. PMID 32015554 DOI: 10.1038/S41594-019-0370-3  0.386
2020 Cho KF, Ma TP, Rose CM, Kirkpatrick DS, Yu K, Blake RA. Chaperone mediated detection of small molecule target binding in cells. Nature Communications. 11: 465. PMID 31974362 DOI: 10.1038/S41467-019-14033-0  0.359
2020 Reichermeier KM, Straube R, Reitsma JM, Sweredoski MJ, Rose CM, Moradian A, den Besten W, Hinkle T, Verschueren E, Petzold G, Thomä NH, Wertz IE, Deshaies RJ, Kirkpatrick DS. PIKES Analysis Reveals Response to Degraders and Key Regulatory Mechanisms of the CRL4 Network. Molecular Cell. PMID 31973889 DOI: 10.1016/J.Molcel.2019.12.013  0.377
2020 Berlin M, Cantley J, Wang J, Bookbinder M, Cadelina G, Chan E, Chen H, Chen X, Davenport K, Fernando T, Gordon D, Hamman B, Haskell R, Ishchenko A, Kirkpatrick DS, et al. Abstract 5687: Selective, chemically-induced degradation of BRM (SMARCA2) enables in vivo efficacy in BRG1 (SMARCA4)-deficient xenograft tumor models Cancer Research. 80: 5687-5687. DOI: 10.1158/1538-7445.Am2020-5687  0.301
2019 Wall CE, Rose CM, Adrian M, Zeng YJ, Kirkpatrick DS, Bingol B. PPEF2 Opposes PINK1-Mediated Mitochondrial Quality Control by Dephosphorylating Ubiquitin. Cell Reports. 29: 3280-3292.e7. PMID 31801089 DOI: 10.1016/J.Celrep.2019.10.130  0.361
2019 Abed M, Verschueren E, Budayeva H, Liu P, Kirkpatrick DS, Reja R, Kummerfeld SK, Webster JD, Gierke S, Reichelt M, Anderson KR, Newman RJ, Roose-Girma M, Modrusan Z, Pektas H, et al. The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification. Plos One. 14: e0214110. PMID 30951545 DOI: 10.1371/Journal.Pone.0214110  0.306
2018 Matsumoto ML, Castellanos ER, Zeng YJ, Kirkpatrick DS. Interpreting the Language of Polyubiquitin with Linkage-Specific Antibodies and Mass Spectrometry. Methods in Molecular Biology (Clifton, N.J.). 1844: 385-400. PMID 30242722 DOI: 10.1007/978-1-4939-8706-1_24  0.356
2018 Heger K, Wickliffe KE, Ndoja A, Zhang J, Murthy A, Dugger DL, Maltzman A, de Sousa E Melo F, Hung J, Zeng Y, Verschueren E, Kirkpatrick DS, Vucic D, Lee WP, Roose-Girma M, et al. OTULIN limits cell death and inflammation by deubiquitinating LUBAC. Nature. PMID 29950720 DOI: 10.1038/S41586-018-0256-2  0.372
2018 Goncharov T, Hedayati S, Mulvihill MM, Izrael-Tomasevic A, Zobel K, Jeet S, Fedorova AV, Eidenschenk C, deVoss J, Yu K, Shaw AS, Kirkpatrick DS, Fairbrother WJ, Deshayes K, Vucic D. Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling. Molecular Cell. 69: 551-565.e7. PMID 29452636 DOI: 10.1016/J.Molcel.2018.01.016  0.332
2018 Cho KF, Rose C, Ma T, Kirkpatrick D, Blake RA. Abstract 775: HIPStA, a high-throughput alternative to CETSA® Cancer Research. 78: 775-775. DOI: 10.1158/1538-7445.Am2018-775  0.336
2017 Whiteley AM, Prado MA, Peng I, Abbas AR, Haley B, Paulo JA, Reichelt M, Katakam A, Sagolla M, Modrusan Z, Lee DY, Roose-Girma M, Kirkpatrick DS, McKenzie BS, Gygi SP, et al. Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins. Elife. 6. PMID 28933694 DOI: 10.7554/Elife.26435  0.4
2017 Dogan T, Gnad F, Chan J, Phu L, Young A, Chen MJ, Doll S, Stokes MP, Belvin M, Friedman LS, Kirkpatrick DS, Hoeflich KP, Hatzivassiliou G. Role of the E3 ubiquitin ligase RNF157 as a novel downstream effector linking PI3K and MAPK signaling to the cell cycle. The Journal of Biological Chemistry. PMID 28655764 DOI: 10.1074/Jbc.M117.792754  0.362
2017 Zhang Z, Newton K, Kummerfeld SK, Webster J, Kirkpatrick DS, Phu L, Eastham-Anderson J, Liu J, Lee WP, Wu J, Li H, Junttila MR, Dixit VM. Transcription factor Etv5 is essential for the maintenance of alveolar type II cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28351980 DOI: 10.1073/Pnas.1621177114  0.317
2017 Whiteley AM, Prado MA, Peng I, Abbas AR, Haley B, Paulo JA, Reichelt M, Katakam A, Sagolla M, Modrusan Z, Lee DY, Roose-Girma M, Kirkpatrick DS, McKenzie BS, Gygi SP, et al. Author response: Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins Elife. DOI: 10.7554/Elife.26435.026  0.309
2017 Song KW, Edgar KA, Kirkpatrick DS, Phu L, Schmidt S, Nannini M, Hong R, Cheng E, Crocker L, Young A, Sampath D, Friedman L. Abstract 146: The PI3K inhibitor, taselisib, has a unique mechanism of action that leads to enhanced potency in PIK3CA mutant models Cancer Research. 77: 146-146. DOI: 10.1158/1538-7445.Am2017-146  0.36
2016 de Almagro MC, Goncharov T, Izrael-Tomasevic A, Duttler S, Kist M, Varfolomeev E, Wu X, Lee WP, Murray J, Webster JD, Yu K, Kirkpatrick DS, Newton K, Vucic D. Coordinated ubiquitination and phosphorylation of RIP1 regulates necroptotic cell death. Cell Death and Differentiation. PMID 27518435 DOI: 10.1038/Cdd.2016.78  0.378
2016 Baughman JM, Rose CM, Kolumam G, Webster JD, Wilkerson EM, Merrill AE, Rhoads TW, Noubade R, Katavolos P, Lesch J, Stapleton DS, Rabaglia ME, Schueler KL, Asuncion R, Domeyer M, ... ... Kirkpatrick DS, et al. NeuCode Proteomics Reveals Bap1 Regulation of Metabolism. Cell Reports. 16: 583-595. PMID 27373151 DOI: 10.1016/J.Celrep.2016.05.096  0.333
2016 Gnad F, Wallin J, Edgar K, Doll S, Arnott D, Robillard L, Kirkpatrick DS, Stokes MP, Vijapurkar U, Hatzivassiliou G, Friedman LS, Belvin M. Quantitative phosphoproteomic analysis of the PI3K-regulated signaling network. Proteomics. PMID 27282143 DOI: 10.1002/Pmic.201600118  0.367
2016 Friedman L, Edgar K, Song K, Schmidt S, Kirkpatrick D, Phu L, Nannini M, Hong R, Cheng E, Crocker L, Young A, Sampath D. Abstract S6-04: The PI3K inhibitor, taselisib, has enhanced potency in PIK3CA mutant models through a unique mechanism of action Cancer Research. 77: 370-370. DOI: 10.1158/1538-7445.Sabcs16-S6-04  0.325
2015 Vartanian S, Ma TP, Lee J, Haverty PM, Kirkpatrick DS, Yu K, Stokoe D. Application of mass spectrometry profiling to establish brusatol as an inhibitor of global protein synthesis. Molecular & Cellular Proteomics : McP. PMID 26711467 DOI: 10.1074/Mcp.M115.055509  0.398
2015 Yu K, Phu L, Varfolomeev E, Bustos D, Vucic D, Kirkpatrick DS. Immunoaffinity enrichment coupled to quantitative mass spectrometry reveals ubiquitin-mediated signaling events. Journal of Molecular Biology. 427: 2121-34. PMID 25861760 DOI: 10.1016/J.Jmb.2015.03.018  0.396
2015 Sodhi JK, Wong S, Kirkpatrick DS, Liu L, Khojasteh SC, Hop CE, Barr JT, Jones JP, Halladay JS. A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 908-15. PMID 25845827 DOI: 10.1124/Dmd.114.061804  0.318
2015 Cunningham CN, Baughman JM, Phu L, Tea JS, Yu C, Coons M, Kirkpatrick DS, Bingol B, Corn JE. USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria. Nature Cell Biology. 17: 160-9. PMID 25621951 DOI: 10.1038/Ncb3097  0.321
2015 Varfolomeev E, Izrael-Tomasevic A, Yu K, Bustos D, Goncharov T, Belmont LD, Masselot A, Bakalarski CE, Kirkpatrick DS, Vucic D. Ubiquitination profiling identifies sensitivity factors for IAP antagonist treatment. The Biochemical Journal. 466: 45-54. PMID 25423073 DOI: 10.1042/Bj20141195  0.404
2014 Dey A, Wu J, Kirkpatrick DS. Interrogation of in vivo protein-protein interactions using transgenic mouse models and stable isotope labeling. Methods in Molecular Biology (Clifton, N.J.). 1176: 179-90. PMID 25030928 DOI: 10.1007/978-1-4939-0992-6_15  0.372
2014 Krutauz D, Reis N, Nakasone MA, Siman P, Zhang D, Kirkpatrick DS, Gygi SP, Brik A, Fushman D, Glickman MH. Extended ubiquitin species are protein-based DUB inhibitors. Nature Chemical Biology. 10: 664-70. PMID 24997605 DOI: 10.1038/Nchembio.1574  0.391
2014 Bingol B, Tea JS, Phu L, Reichelt M, Bakalarski CE, Song Q, Foreman O, Kirkpatrick DS, Sheng M. The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy. Nature. 510: 370-5. PMID 24896179 DOI: 10.1038/Nature13418  0.305
2014 Anania VG, Pham VC, Huang X, Masselot A, Lill JR, Kirkpatrick DS. Peptide level immunoaffinity enrichment enhances ubiquitination site identification on individual proteins. Molecular & Cellular Proteomics : McP. 13: 145-56. PMID 24142993 DOI: 10.1074/Mcp.M113.031062  0.39
2013 Kirkpatrick DS, Bustos DJ, Dogan T, Chan J, Phu L, Young A, Friedman LS, Belvin M, Song Q, Bakalarski CE, Hoeflich KP. Phosphoproteomic characterization of DNA damage response in melanoma cells following MEK/PI3K dual inhibition. Proceedings of the National Academy of Sciences of the United States of America. 110: 19426-31. PMID 24218548 DOI: 10.1073/Pnas.1309473110  0.365
2013 Pozniak CD, Sengupta Ghosh A, Gogineni A, Hanson JE, Lee SH, Larson JL, Solanoy H, Bustos D, Li H, Ngu H, Jubb AM, Ayalon G, Wu J, Scearce-Levie K, Zhou Q, ... ... Kirkpatrick DS, et al. Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration. The Journal of Experimental Medicine. 210: 2553-67. PMID 24166713 DOI: 10.1084/Jem.20122832  0.336
2013 Huntwork-Rodriguez S, Wang B, Watkins T, Ghosh AS, Pozniak CD, Bustos D, Newton K, Kirkpatrick DS, Lewcock JW. JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis. The Journal of Cell Biology. 202: 747-63. PMID 23979718 DOI: 10.1083/Jcb.201303066  0.33
2013 Phillips AH, Zhang Y, Cunningham CN, Zhou L, Forrest WF, Liu PS, Steffek M, Lee J, Tam C, Helgason E, Murray JM, Kirkpatrick DS, Fairbrother WJ, Corn JE. Conformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signaling. Proceedings of the National Academy of Sciences of the United States of America. 110: 11379-84. PMID 23801757 DOI: 10.1073/Pnas.1302407110  0.347
2013 Goncharov T, Niessen K, de Almagro MC, Izrael-Tomasevic A, Fedorova AV, Varfolomeev E, Arnott D, Deshayes K, Kirkpatrick DS, Vucic D. OTUB1 modulates c-IAP1 stability to regulate signalling pathways. The Embo Journal. 32: 1103-14. PMID 23524849 DOI: 10.1038/Emboj.2013.62  0.375
2013 Anania VG, Bustos DJ, Lill JR, Kirkpatrick DS, Coscoy L. A Novel Peptide-Based SILAC Method to Identify the Posttranslational Modifications Provides Evidence for Unconventional Ubiquitination in the ER-Associated Degradation Pathway. International Journal of Proteomics. 2013: 857918. PMID 23431445 DOI: 10.1155/2013/857918  0.373
2013 Tran H, Bustos D, Yeh R, Rubinfeld B, Lam C, Shriver S, Zilberleyb I, Lee MW, Phu L, Sarkar AA, Zohn IE, Wertz IE, Kirkpatrick DS, Polakis P. HectD1 E3 ligase modifies adenomatous polyposis coli (APC) with polyubiquitin to promote the APC-axin interaction. The Journal of Biological Chemistry. 288: 3753-67. PMID 23277359 DOI: 10.1074/Jbc.M112.415240  0.34
2012 Dey A, Seshasayee D, Noubade R, French DM, Liu J, Chaurushiya MS, Kirkpatrick DS, Pham VC, Lill JR, Bakalarski CE, Wu J, Phu L, Katavolos P, LaFave LM, Abdel-Wahab O, et al. Loss of the tumor suppressor BAP1 causes myeloid transformation. Science (New York, N.Y.). 337: 1541-6. PMID 22878500 DOI: 10.1126/Science.1221711  0.309
2012 Bustos D, Bakalarski CE, Yang Y, Peng J, Kirkpatrick DS. Characterizing ubiquitination sites by peptide-based immunoaffinity enrichment. Molecular & Cellular Proteomics : McP. 11: 1529-40. PMID 22729469 DOI: 10.1074/Mcp.R112.019117  0.333
2012 Pham VC, Pitti R, Anania VG, Bakalarski CE, Bustos D, Jhunjhunwala S, Phung QT, Yu K, Forrest WF, Kirkpatrick DS, Ashkenazi A, Lill JR. Complementary proteomic tools for the dissection of apoptotic proteolysis events. Journal of Proteome Research. 11: 2947-54. PMID 22432722 DOI: 10.1021/Pr300035K  0.379
2012 Dimova NV, Hathaway NA, Lee BH, Kirkpatrick DS, Berkowitz ML, Gygi SP, Finley D, King RW. APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1. Nature Cell Biology. 14: 168-76. PMID 22286100 DOI: 10.1038/Ncb2425  0.344
2011 Dong KC, Helgason E, Yu C, Phu L, Arnott DP, Bosanac I, Compaan DM, Huang OW, Fedorova AV, Kirkpatrick DS, Hymowitz SG, Dueber EC. Preparation of distinct ubiquitin chain reagents of high purity and yield. Structure (London, England : 1993). 19: 1053-63. PMID 21827942 DOI: 10.1016/J.Str.2011.06.010  0.371
2011 Callow MG, Tran H, Phu L, Lau T, Lee J, Sandoval WN, Liu PS, Bheddah S, Tao J, Lill JR, Hongo JA, Davis D, Kirkpatrick DS, Polakis P, Costa M. Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling. Plos One. 6: e22595. PMID 21799911 DOI: 10.1371/Journal.Pone.0022595  0.425
2011 Huang X, Summers MK, Pham V, Lill JR, Liu J, Lee G, Kirkpatrick DS, Jackson PK, Fang G, Dixit VM. Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry. Molecular Cell. 42: 511-23. PMID 21596315 DOI: 10.1016/J.Molcel.2011.03.027  0.325
2011 Ziv I, Matiuhin Y, Kirkpatrick DS, Erpapazoglou Z, Leon S, Pantazopoulou M, Kim W, Gygi SP, Haguenauer-Tsapis R, Reis N, Glickman MH, Kleifeld O. A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis. Molecular & Cellular Proteomics : McP. 10: M111.009753. PMID 21427232 DOI: 10.1074/Mcp.M111.009753  0.403
2011 Bosanac I, Phu L, Pan B, Zilberleyb I, Maurer B, Dixit VM, Hymowitz SG, Kirkpatrick DS. Modulation of K11-linkage formation by variable loop residues within UbcH5A. Journal of Molecular Biology. 408: 420-31. PMID 21396940 DOI: 10.1016/J.Jmb.2011.03.011  0.313
2011 Westlake CJ, Baye LM, Nachury MV, Wright KJ, Ervin KE, Phu L, Chalouni C, Beck JS, Kirkpatrick DS, Slusarski DC, Sheffield VC, Scheller RH, Jackson PK. Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome. Proceedings of the National Academy of Sciences of the United States of America. 108: 2759-64. PMID 21273506 DOI: 10.1073/Pnas.1018823108  0.317
2011 Chu CW, Hou F, Zhang J, Phu L, Loktev AV, Kirkpatrick DS, Jackson PK, Zhao Y, Zou H. A novel acetylation of β-tubulin by San modulates microtubule polymerization via down-regulating tubulin incorporation. Molecular Biology of the Cell. 22: 448-56. PMID 21177827 DOI: 10.1091/Mbc.E10-03-0203  0.306
2011 Phu L, Izrael-Tomasevic A, Matsumoto ML, Bustos D, Dynek JN, Fedorova AV, Bakalarski CE, Arnott D, Deshayes K, Dixit VM, Kelley RF, Vucic D, Kirkpatrick DS. Improved quantitative mass spectrometry methods for characterizing complex ubiquitin signals. Molecular & Cellular Proteomics : McP. 10: M110.003756. PMID 21048196 DOI: 10.1074/Mcp.M110.003756  0.36
2010 Dynek JN, Goncharov T, Dueber EC, Fedorova AV, Izrael-Tomasevic A, Phu L, Helgason E, Fairbrother WJ, Deshayes K, Kirkpatrick DS, Vucic D. c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling. The Embo Journal. 29: 4198-209. PMID 21113135 DOI: 10.1038/Emboj.2010.300  0.39
2010 Bosanac I, Wertz IE, Pan B, Yu C, Kusam S, Lam C, Phu L, Phung Q, Maurer B, Arnott D, Kirkpatrick DS, Dixit VM, Hymowitz SG. Ubiquitin binding to A20 ZnF4 is required for modulation of NF-κB signaling. Molecular Cell. 40: 548-57. PMID 21095585 DOI: 10.1016/J.Molcel.2010.10.009  0.319
2010 Matsumoto ML, Wickliffe KE, Dong KC, Yu C, Bosanac I, Bustos D, Phu L, Kirkpatrick DS, Hymowitz SG, Rape M, Kelley RF, Dixit VM. K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody. Molecular Cell. 39: 477-84. PMID 20655260 DOI: 10.1016/J.Molcel.2010.07.001  0.312
2010 Isasa M, Katz EJ, Kim W, Yugo V, González S, Kirkpatrick DS, Thomson TM, Finley D, Gygi SP, Crosas B. Monoubiquitination of RPN10 regulates substrate recruitment to the proteasome. Molecular Cell. 38: 733-45. PMID 20542005 DOI: 10.1016/J.Molcel.2010.05.001  0.39
2010 Ryu H, Al-Ani G, Deckert K, Kirkpatrick D, Gygi SP, Dasso M, Azuma Y. PIASy mediates SUMO-2/3 conjugation of poly(ADP-ribose) polymerase 1 (PARP1) on mitotic chromosomes. The Journal of Biological Chemistry. 285: 14415-23. PMID 20228053 DOI: 10.1074/Jbc.M109.074583  0.315
2009 Kirkpatrick DS, Dixit VM. GPS navigation of the protein-stability landscape. Nature Biotechnology. 27: 46-8. PMID 19131998 DOI: 10.1038/Nbt0109-46  0.328
2009 Blankenship JW, Varfolomeev E, Goncharov T, Fedorova AV, Kirkpatrick DS, Izrael-Tomasevic A, Phu L, Arnott D, Aghajan M, Zobel K, Bazan JF, Fairbrother WJ, Deshayes K, Vucic D. Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1). The Biochemical Journal. 417: 149-60. PMID 18939944 DOI: 10.1042/Bj20081885  0.311
2008 Matiuhin Y, Kirkpatrick DS, Ziv I, Kim W, Dakshinamurthy A, Kleifeld O, Gygi SP, Reis N, Glickman MH. Extraproteasomal Rpn10 restricts access of the polyubiquitin-binding protein Dsk2 to proteasome. Molecular Cell. 32: 415-25. PMID 18995839 DOI: 10.1016/J.Molcel.2008.10.011  0.403
2008 Sliter DA, Kubota K, Kirkpatrick DS, Alzayady KJ, Gygi SP, Wojcikiewicz RJ. Mass spectrometric analysis of type 1 inositol 1,4,5-trisphosphate receptor ubiquitination. The Journal of Biological Chemistry. 283: 35319-28. PMID 18955483 DOI: 10.1074/Jbc.M807288200  0.312
2008 Newton K, Matsumoto ML, Wertz IE, Kirkpatrick DS, Lill JR, Tan J, Dugger D, Gordon N, Sidhu SS, Fellouse FA, Komuves L, French DM, Ferrando RE, Lam C, Compaan D, et al. Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies. Cell. 134: 668-78. PMID 18724939 DOI: 10.1016/J.Cell.2008.07.039  0.366
2008 Wainszelbaum MJ, Charron AJ, Kong C, Kirkpatrick DS, Srikanth P, Barbieri MA, Gygi SP, Stahl PD. The hominoid-specific oncogene TBC1D3 activates Ras and modulates epidermal growth factor receptor signaling and trafficking. The Journal of Biological Chemistry. 283: 13233-42. PMID 18319245 DOI: 10.1074/Jbc.M800234200  0.321
2008 Tan JM, Wong ES, Kirkpatrick DS, Pletnikova O, Ko HS, Tay SP, Ho MW, Troncoso J, Gygi SP, Lee MK, Dawson VL, Dawson TM, Lim KL. Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases. Human Molecular Genetics. 17: 431-9. PMID 17981811 DOI: 10.1093/Hmg/Ddm320  0.36
2007 Ménétret JF, Schaletzky J, Clemons WM, Osborne AR, Skånland SS, Denison C, Gygi SP, Kirkpatrick DS, Park E, Ludtke SJ, Rapoport TA, Akey CW. Ribosome binding of a single copy of the SecY complex: implications for protein translocation. Molecular Cell. 28: 1083-92. PMID 18158904 DOI: 10.1016/J.Molcel.2007.10.034  0.301
2007 Kleijnen MF, Kirkpatrick DS, Gygi SP. The ubiquitin-proteasome system regulates membrane fusion of yeast vacuoles. The Embo Journal. 26: 275-87. PMID 17183369 DOI: 10.1038/Sj.Emboj.7601486  0.331
2006 Crosas B, Hanna J, Kirkpatrick DS, Zhang DP, Tone Y, Hathaway NA, Buecker C, Leggett DS, Schmidt M, King RW, Gygi SP, Finley D. Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities. Cell. 127: 1401-13. PMID 17190603 DOI: 10.1016/J.Cell.2006.09.051  0.37
2006 Kirkpatrick DS, Hathaway NA, Hanna J, Elsasser S, Rush J, Finley D, King RW, Gygi SP. Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology. Nature Cell Biology. 8: 700-10. PMID 16799550 DOI: 10.1038/Ncb1436  0.387
2006 Huang F, Kirkpatrick D, Jiang X, Gygi S, Sorkin A. Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain. Molecular Cell. 21: 737-48. PMID 16543144 DOI: 10.1016/J.Molcel.2006.02.018  0.312
2005 Kirkpatrick DS, Denison C, Gygi SP. Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomics. Nature Cell Biology. 7: 750-7. PMID 16056266 DOI: 10.1038/Ncb0805-750  0.374
2005 Kirkpatrick DS, Weldon SF, Tsaprailis G, Liebler DC, Gandolfi AJ. Proteomic identification of ubiquitinated proteins from human cells expressing His-tagged ubiquitin. Proteomics. 5: 2104-11. PMID 15852347 DOI: 10.1002/Pmic.200401089  0.553
2005 Kirkpatrick DS, Gerber SA, Gygi SP. The absolute quantification strategy: a general procedure for the quantification of proteins and post-translational modifications. Methods (San Diego, Calif.). 35: 265-73. PMID 15722223 DOI: 10.1016/J.Ymeth.2004.08.018  0.346
2005 Denison C, Kirkpatrick DS, Gygi SP. Proteomic insights into ubiquitin and ubiquitin-like proteins. Current Opinion in Chemical Biology. 9: 69-75. PMID 15701456 DOI: 10.1016/J.Cbpa.2004.10.010  0.387
2004 Tanny JC, Kirkpatrick DS, Gerber SA, Gygi SP, Moazed D. Budding yeast silencing complexes and regulation of Sir2 activity by protein-protein interactions. Molecular and Cellular Biology. 24: 6931-46. PMID 15282295 DOI: 10.1128/Mcb.24.16.6931-6946.2004  0.347
2003 Catania JM, Parrish AR, Kirkpatrick DS, Chitkara M, Bowden GT, Henderson CJ, Wolf CR, Clark AJ, Brendel K, Fisher RL, Gandolfi AJ. Precision-cut tissue slices from transgenic mice as an in vitro toxicology system. Toxicology in Vitro : An International Journal Published in Association With Bibra. 17: 201-5. PMID 12650674 DOI: 10.1016/S0887-2333(03)00004-3  0.691
2003 Kirkpatrick DS, Dale KV, Catania JM, Gandolfi AJ. Low-level arsenite causes accumulation of ubiquitinated proteins in rabbit renal cortical slices and HEK293 cells. Toxicology and Applied Pharmacology. 186: 101-9. PMID 12639501 DOI: 10.1016/S0041-008X(02)00019-4  0.721
2003 Kirkpatrick D, Dale K, Catania J, Gandolfi A. Erratum to “low-level arsenite causes accumulation of ubiquitinated proteins in rabbit renal cortical slices and hek923 cells” [toxicol. appl. pharmacol. 186 (2003) 101–109]☆ Toxicology and Applied Pharmacology. 193: 393. DOI: 10.1016/J.Taap.2003.08.007  0.709
Low-probability matches (unlikely to be authored by this person)
2012 Matsumoto ML, Dong KC, Yu C, Phu L, Gao X, Hannoush RN, Hymowitz SG, Kirkpatrick DS, Dixit VM, Kelley RF. Engineering and structural characterization of a linear polyubiquitin-specific antibody. Journal of Molecular Biology. 418: 134-44. PMID 22227388 DOI: 10.1016/J.Jmb.2011.12.053  0.295
2020 Ndoja A, Reja R, Lee SH, Webster JD, Ngu H, Rose CM, Kirkpatrick DS, Modrusan Z, Chen YJ, Dugger DL, Gandham V, Xie L, Newton K, Dixit VM. Ubiquitin Ligase COP1 Suppresses Neuroinflammation by Degrading c/EBPβ in Microglia. Cell. PMID 32795415 DOI: 10.1016/J.Cell.2020.07.011  0.295
2019 Fleck D, Phu L, Verschueren E, Hinkle T, Reichelt M, Bhangale T, Haley B, Wang Y, Graham R, Kirkpatrick DS, Sheng M, Bingol B. PTCD1 is required for mitochondrial oxidative-phosphorylation: possible genetic association with Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30948477 DOI: 10.1523/Jneurosci.0116-19.2019  0.286
2018 Samie M, Lim J, Verschueren E, Baughman JM, Peng I, Wong A, Kwon Y, Senbabaoglu Y, Hackney JA, Keir M, Mckenzie B, Kirkpatrick DS, van Lookeren Campagne M, Murthy A. Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling. Nature Immunology. PMID 29358708 DOI: 10.1038/S41590-017-0042-6  0.286
2013 Wilson CR, Nicholes K, Bustos D, Lin E, Shi L, Kirkpatrick D, Settleman J. Abstract 4462: Resistance to selective kinase inhibitors upon epithelial to mesenchymal transition. Cancer Research. 73: 4462-4462. DOI: 10.1158/1538-7445.Am2013-4462  0.283
2014 Wilson C, Nicholes K, Bustos D, Lin E, Song Q, Stephan JP, Kirkpatrick DS, Settleman J. Overcoming EMT-associated resistance to anti-cancer drugs via Src/FAK pathway inhibition. Oncotarget. 5: 7328-41. PMID 25193862 DOI: 10.18632/Oncotarget.2397  0.281
2010 Ryu H, Furuta M, Kirkpatrick D, Gygi SP, Azuma Y. PIASy-dependent SUMOylation regulates DNA topoisomerase IIalpha activity. The Journal of Cell Biology. 191: 783-94. PMID 21079245 DOI: 10.1083/Jcb.201004033  0.279
2016 Bakalarski CE, Kirkpatrick DS. A Biologist's Field Guide to Multiplexed Quantitative Proteomics. Molecular & Cellular Proteomics : McP. PMID 26873251 DOI: 10.1074/Mcp.O115.056986  0.271
2015 Rutz S, Kayagaki N, Phung QT, Eidenschenk C, Noubade R, Wang X, Lesch J, Lu R, Newton K, Huang OW, Cochran AG, Vasser M, Fauber BP, DeVoss J, Webster J, ... ... Kirkpatrick DS, et al. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature. 518: 417-21. PMID 25470037 DOI: 10.1038/Nature13979  0.268
2015 Zuchero YJ, Chen X, Bien-Ly N, Bumbaca D, Tong RK, Gao X, Zhang S, Hoyte K, Luk W, Huntley MA, Phu L, Tan C, Kallop D, Weimer RM, Lu Y, ... Kirkpatrick DS, et al. Discovery of Novel Blood-Brain Barrier Targets to Enhance Brain Uptake of Therapeutic Antibodies. Neuron. PMID 26687840 DOI: 10.1016/J.Neuron.2015.11.024  0.263
2018 Sengupta-Ghosh A, Dominguez SL, Xie L, Barck KH, Jiang Z, Earr T, Imperio J, Phu L, Budayeva HG, Kirkpatrick DS, Cai H, Eastham-Anderson J, Ngu H, Foreman O, Hedehus M, et al. Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1 mouse model of ALS. Neurobiology of Disease. 124: 340-352. PMID 30528255 DOI: 10.1016/J.Nbd.2018.12.002  0.262
2018 Rose CM, Erickson BK, Schweppe DK, Viner R, Choi J, Rogers J, Bomgarden R, Gygi SP, Kirkpatrick DS. TomahaqCompanion: A tool for the creation and analysis of isobaric label based multiplexed targeted assays. Journal of Proteome Research. PMID 30501201 DOI: 10.1021/Acs.Jproteome.8B00767  0.262
1973 Kirkpatrick DS, Bishop SH. Phosphonoprotein. Characterization of aminophosphonic acid rich glycoproteins from sea anemones Biochemistry. 12: 2829-2840. PMID 4146291 DOI: 10.1021/Bi00739A009  0.257
2020 Suryamohan K, Krishnankutty SP, Guillory J, Jevit M, Schröder MS, Wu M, Kuriakose B, Mathew OK, Perumal RC, Koludarov I, Goldstein LD, Senger K, Dixon MD, Velayutham D, Vargas D, ... ... Kirkpatrick DS, et al. The Indian cobra reference genome and transcriptome enables comprehensive identification of venom toxins. Nature Genetics. PMID 31907489 DOI: 10.1038/S41588-019-0559-8  0.256
2012 Sheng Z, Zhang S, Bustos D, Kleinheinz T, Le Pichon CE, Dominguez SL, Solanoy HO, Drummond J, Zhang X, Ding X, Cai F, Song Q, Li X, Yue Z, van der Brug MP, ... ... Kirkpatrick DS, et al. Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutations. Science Translational Medicine. 4: 164ra161. PMID 23241745 DOI: 10.1126/Scitranslmed.3004485  0.245
2019 Sengupta-Ghosh A, Dominguez SL, Xie L, Barck KH, Jiang Z, Earr T, Imperio J, Phu L, Budayeva HG, Kirkpatrick DS, Cai H, He D, Eastham-Anderson J, Ngu H, Foreman O, et al. Corrigendum to "Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS" Neurobiology of Disease 124 (2019) 340-352. Neurobiology of Disease. 104558. PMID 31471201 DOI: 10.1016/J.Nbd.2019.104558  0.245
2020 Vogl AM, Phu L, Becerra R, Giusti SA, Verschueren E, Hinkle TB, Bordenave MD, Adrian M, Heidersbach A, Yankilevich P, Stefani FD, Wurst W, Hoogenraad CC, Kirkpatrick DS, Refojo D, et al. Publisher Correction: Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics. Nature Structural & Molecular Biology. PMID 32103165 DOI: 10.1038/S41594-020-0395-7  0.241
2006 Hanna J, Hathaway NA, Tone Y, Crosas B, Elsasser S, Kirkpatrick DS, Leggett DS, Gygi SP, King RW, Finley D. Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation. Cell. 127: 99-111. PMID 17018280 DOI: 10.1016/J.Cell.2006.07.038  0.236
2023 Rosenberg SC, Shanahan F, Yamazoe S, Kschonsak M, Zeng YJ, Lee J, Plise E, Yen I, Rose CM, Quinn JG, Gazzard LJ, Walters BT, Kirkpatrick DS, Staben ST, Foster SA, et al. Ternary complex dissociation kinetics contribute to mutant-selective EGFR degradation. Cell Chemical Biology. PMID 36773603 DOI: 10.1016/j.chembiol.2023.01.007  0.232
2005 Finley D, Crosas B, Schmidt M, Hanna J, Kirkpatrick D, Elsasser S, Walz T, Gygi S. The Proteasome and its Associated Proteins Gbm Annual Spring Meeting Mosbach 2005. 2005. DOI: 10.1240/sav_gbm_2005_m_001027  0.23
2005 Finley D, Crosas B, Hanna J, Kirkpatrick D, Zhang D, Elsasser S, Gygi S. The proteasome and its associated proteins Gbm Annual Fall Meeting Berlin/Potsdam 2005. 2005. DOI: 10.1240/sav_gbm_2005_h_001468  0.23
2024 Li J, Purser N, Liwocha J, Scott DC, Byers HA, Steigenberger B, Hill S, Tripathi-Giesgen I, Hinkle T, Hansen FM, Prabu JR, Radhakrishnan SK, Kirkpatrick DS, Reichermeier KM, Schulman BA, et al. Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting. Molecular Cell. PMID 38382526 DOI: 10.1016/j.molcel.2024.01.022  0.217
2021 Song KW, Edgar KA, Hanan EJ, Hafner M, Oeh J, Merchant M, Sampath D, Nannini MA, Hong R, Phu L, Forrest WF, Stawiski E, Schmidt S, Endres N, Guan J, ... ... Kirkpatrick DS, et al. RTK-dependent inducible degradation of mutant PI3Kα drives GDC-0077 (Inavolisib) efficacy. Cancer Discovery. PMID 34544753 DOI: 10.1158/2159-8290.CD-21-0072  0.205
2023 Ma TP, Izrael-Tomasevic A, Mroue R, Budayeva H, Malhotra S, Raisner R, Evangelista M, Rose CM, Kirkpatrick DS, Yu K. AzidoTMT Enables Direct Enrichment and Highly Multiplexed Quantitation of Proteome-Wide Functional Residues. Journal of Proteome Research. PMID 37285454 DOI: 10.1021/acs.jproteome.2c00703  0.203
2022 Venkatanarayan A, Liang J, Yen I, Shanahan F, Haley B, Phu L, Verschueren E, Hinkle TB, Kan D, Segal E, Long JE, Lima T, Liau NPD, Sudhamsu J, Li J, ... ... Kirkpatrick DS, et al. CRAF dimerization with ARAF regulates KRAS-driven tumor growth. Cell Reports. 38: 110351. PMID 35139374 DOI: 10.1016/j.celrep.2022.110351  0.193
1968 Peck EJ, Kirkpatrick DS, Ray WJ. Thermodynamics of phosphate transfer in the phosphoglucomutase system. Biochemistry. 7: 152-162. PMID 4320436 DOI: 10.1021/Bi00841A020  0.186
2022 Budayeva HG, Sengupta-Ghosh A, Phu L, Moffat JG, Ayalon G, Kirkpatrick DS. Phosphoproteome Profiling of the Receptor Tyrosine Kinase MuSK Identifies Tyrosine Phosphorylation of Rab GTPases. Molecular & Cellular Proteomics : McP. 100221. PMID 35227894 DOI: 10.1016/j.mcpro.2022.100221  0.155
1972 Bishop SH, Barnes LB, Kirkpatrick DS. Adenosine deaminase from Metridium senile (L.), a sea anemone Comparative Biochemistry and Physiology -- Part B: Biochemistry And. 43: 949-963. PMID 4145714 DOI: 10.1016/0305-0491(72)90239-8  0.153
2021 Davies CW, Vidal SE, Phu L, Sudhamsu J, Hinkle TB, Chan Rosenberg S, Schumacher FR, Zeng YJ, Schwerdtfeger C, Peterson AS, Lill JR, Rose CM, Shaw AS, Wertz IE, Kirkpatrick DS, et al. Antibody toolkit reveals N-terminally ubiquitinated substrates of UBE2W. Nature Communications. 12: 4608. PMID 34326324 DOI: 10.1038/s41467-021-24669-6  0.149
2021 Maculins T, Verschueren E, Hinkle T, Choi M, Chang P, Chalouni C, Rao S, Kwon Y, Lim J, Katakam AK, Kunz RC, Erickson BK, Huang T, Tsai TH, Vitek O, ... ... Kirkpatrick DS, et al. Multiplexed proteomics of autophagy-deficient murine macrophages reveals enhanced antimicrobial immunity via the oxidative stress response. Elife. 10. PMID 34085925 DOI: 10.7554/eLife.62320  0.138
2023 Chen JK, Merrick KA, Kong YW, Izrael-Tomasevic A, Eng G, Handly ED, Patterson JC, Cannell IG, Suarez-Lopez L, Hosios AM, Dinh A, Kirkpatrick DS, Yu K, Rose CM, Hernandez JM, et al. An RNA Damage Response Network Mediates the Lethality of 5-FU in Clinically Relevant Tumor Types. Biorxiv : the Preprint Server For Biology. PMID 37162991 DOI: 10.1101/2023.04.28.538590  0.133
2023 Guidi R, Wedeles C, Xu D, Kolmus K, Headland SE, Teng G, Guillory J, Zeng YJ, Cheung TK, Chaudhuri S, Modrusan Z, Liang Y, Horswell S, Haley B, Rutz S, ... ... Kirkpatrick DS, et al. Argonaute3-SF3B3 complex controls pre-mRNA splicing to restrain type 2 immunity. Cell Reports. 42: 113515. PMID 38096048 DOI: 10.1016/j.celrep.2023.113515  0.128
2021 Stark K, Goncharov T, Varfolomeev E, Xie L, Ngu H, Peng I, Anderson KR, Verschueren E, Choi M, Kirkpatrick DS, Easton A, Webster JD, McKenzie BS, Vucic D, Bingol B. Genetic inactivation of RIP1 kinase activity in rats protects against ischemic brain injury. Cell Death & Disease. 12: 379. PMID 33828080 DOI: 10.1038/s41419-021-03651-6  0.12
1978 McGinness JE, Proctor PH, Demopoulos HB, Hokanson JA, Kirkpatrick DS. Amelioration of cis-platinum nephrotoxicity by orgotein (superoxide dismutase). Physiological Chemistry and Physics. 10: 267-77. PMID 733940  0.094
1980 Moorhead LC, Redburn DA, Kirkpatrick DS, Kretzer F. Bacterial Collagenase: Proposed Adjunct to Vitrectomy With Membranectomy Archives of Ophthalmology. 98: 1829-1839. PMID 6252879 DOI: 10.1001/archopht.1980.01020040681018  0.09
2013 Pozniak CD, Sengupta Ghosh A, Gogineni A, Hanson JE, Lee S, Larson JL, Solanoy H, Bustos D, Li H, Ngu H, Jubb AM, Ayalon G, Wu J, Scearce-Levie K, Zhou Q, ... ... Kirkpatrick DS, et al. Dual leucine zipper kinase is required for excitotoxicity induced neuronal degeneration The Journal of Cell Biology. 203: 2033OIA132. DOI: 10.1083/jcb.2033OIA132  0.088
1977 Hurley JC, Bunde TA, Dell JC, Kirkpatrick DS, Bishop SH. Phosphonoglycoprotein from Metridium senile-heterogeneity of glycoproteins containing aminoethylphosphonic acid Comparative Biochemistry and Physiology -- Part B: Biochemistry And. 58: 253-259. PMID 45526 DOI: 10.1016/0305-0491(77)90199-7  0.075
1974 Mailman ML, Kirkpatrick DS, Dresden MH. A partial characterization of collagens from Notophthalmus viridescens and Rana catesbiana. Comparative Biochemistry and Physiology. B, Comparative Biochemistry. 47: 617-30. PMID 4548869 DOI: 10.1016/0305-0491(74)90010-8  0.052
1979 McGinness JE, Crippa PR, Kirkpatrick DS, Proctor PH. Reversible and irreversible changes in hydrogen ion titration curves of melanins Physiological Chemistry and Physics. 11: 217-223. PMID 43543  0.051
1971 Kirkpatrick DS, Bishop SH. Simplified wet ash procedure for total phosphorus analysis of organophosphonates in biological samples Analytical Chemistry. 43: 1707-1709. PMID 5130420  0.026
1966 Ray WJ, Roscelli GA, Kirkpatrick DS. The addition and release of magnesium in the phosphoglucomutase reaction. I. Evidence for a random order of addition Journal of Biological Chemistry. 241: 2603-2610. PMID 5911633  0.019
1976 Venkataraman L, Garza HM, Kirkpatrick DS. Fluorescamine as an external membrane marker - erythrocytes and frog rod outer segments Biophysical Journal. 16.  0.011
1978 Kirkpatrick DS, McGinness JE, Moorhead WD, Corry PM, Proctor PH. High-frequency dielectric spectroscopy of concentrated membrane suspensions Biophysical Journal. 24: 243-245. PMID 708826  0.01
Hide low-probability matches.