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Drew M. Pardoll - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Molecular Biology, Immunology, Cell Biology
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Year Citation  Score
2024 Pulliam T, Jani S, Jing L, Ryu H, Jojic A, Shasha C, Zhang J, Kulikauskas R, Church C, Garnett-Benson C, Gooley T, Chapuis A, Paulson K, Smith KN, Pardoll DM, et al. Circulating cancer-specific CD8 T cell frequency is associated with response to PD-1 blockade in Merkel cell carcinoma. Cell Reports. Medicine. 101412. PMID 38340723 DOI: 10.1016/j.xcrm.2024.101412  0.388
2024 Zheng Y, Lebid A, Chung L, Fu J, Wang X, Otrocol A, Zarif JC, Yu H, Llosa NJ, Pardoll DM. Targeting the activin receptor 1C on CD4+ T cells for cancer immunotherapy. Oncoimmunology. 13: 2297503. PMID 38235319 DOI: 10.1080/2162402X.2023.2297503  0.399
2023 Bergerud KMB, Berkseth M, Pardoll DM, Ganguly S, Kleinberg LR, Lawrence J, Odde DJ, Largaespada DA, Terezakis SA, Sloan L. Radiation Therapy and Myeloid-derived Suppressor Cells: Breaking Down Their Cancerous Partnership. International Journal of Radiation Oncology, Biology, Physics. PMID 38042450 DOI: 10.1016/j.ijrobp.2023.11.050  0.3
2023 Dykema AG, Zhang J, Cheung LS, Connor S, Zhang B, Zeng Z, Cherry CM, Li T, Caushi JX, Nishimoto M, Munoz AJ, Ji Z, Hou W, Zhan W, Singh D, ... ... Pardoll DM, et al. Lung tumor-infiltrating T have divergent transcriptional profiles and function linked to checkpoint blockade response. Science Immunology. 8: eadg1487. PMID 37713507 DOI: 10.1126/sciimmunol.adg1487  0.384
2023 Wright KM, DiNapoli SR, Miller MS, Aitana Azurmendi P, Zhao X, Yu Z, Chakrabarti M, Shi W, Douglass J, Hwang MS, Hsiue EH, Mog BJ, Pearlman AH, Paul S, Konig MF, ... Pardoll DM, et al. Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen. Nature Communications. 14: 5063. PMID 37604828 DOI: 10.1038/s41467-023-40821-w  0.616
2022 Schad SE, Chow A, Mangarin L, Pan H, Zhang J, Ceglia N, Caushi JX, Malandro N, Zappasodi R, Gigoux M, Hirschhorn D, Budhu S, Amisaki M, Arniella M, Redmond D, ... ... Pardoll D, et al. Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions. The Journal of Experimental Medicine. 219. PMID 35604411 DOI: 10.1084/jem.20212169  0.387
2022 Dykema AG, Zhang B, Woldemeskel BA, Garliss CC, Rashid R, Westlake T, Zhang L, Zhang J, Cheung LS, Caushi JX, Pardoll DM, Cox AL, Ji H, Smith KN, Blankson JN. SARS-CoV-2 vaccination diversifies the CD4+ spike-reactive T cell repertoire in patients with prior SARS-CoV-2 infection. Ebiomedicine. 80: 104048. PMID 35533495 DOI: 10.1016/j.ebiom.2022.104048  0.318
2022 Pearlman AH, Hwang MS, Konig MF, Hsiue EH, Douglass J, DiNapoli SR, Mog BJ, Bettegowda C, Pardoll DM, Gabelli SB, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Author Correction: Targeting public neoantigens for cancer immunotherapy. Nature Cancer. 2: 865-867. PMID 35122030 DOI: 10.1038/s43018-021-00246-0  0.614
2021 Pearlman AH, Hwang MS, Konig MF, Hsiue EH, Douglass J, DiNapoli SR, Mog BJ, Bettegowda C, Pardoll DM, Gabelli SB, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Targeting public neoantigens for cancer immunotherapy. Nature Cancer. 2: 487-497. PMID 34676374 DOI: 10.1038/s43018-021-00210-y  0.633
2021 Caushi JX, Zhang J, Ji Z, Vaghasia A, Zhang B, Hsiue EH, Mog BJ, Hou W, Justesen S, Blosser R, Tam A, Anagnostou V, Cottrell TR, Guo H, Chan HY, ... ... Pardoll DM, et al. Author Correction: Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers. Nature. PMID 34608287 DOI: 10.1038/s41586-021-03893-6  0.375
2021 Hwang MS, Miller MS, Thirawatananond P, Douglass J, Wright KM, Hsiue EH, Mog BJ, Aytenfisu TY, Murphy MB, Aitana Azurmendi P, Skora AD, Pearlman AH, Paul S, DiNapoli SR, Konig MF, ... ... Pardoll DM, et al. Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens. Nature Communications. 12: 5271. PMID 34489470 DOI: 10.1038/s41467-021-25605-4  0.683
2021 Caushi JX, Zhang J, Ji Z, Vaghasia A, Zhang B, Hsiue EH, Mog BJ, Hou W, Justesen S, Blosser R, Tam A, Anagnostou V, Cottrell TR, Guo H, Chan HY, ... ... Pardoll DM, et al. Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers. Nature. PMID 34290408 DOI: 10.1038/s41586-021-03752-4  0.526
2021 Dykema AG, Zhang B, Woldemeskel BA, Garliss CC, Cheung LS, Choudhury D, Zhang J, Aparicio L, Bom S, Rashid R, Caushi JX, Hsiue EH, Cascino K, Thompson EA, Kwaa AK, ... ... Pardoll DM, et al. Functional characterization of CD4+ T-cell receptors cross-reactive for SARS-CoV-2 and endemic coronaviruses. The Journal of Clinical Investigation. PMID 33830946 DOI: 10.1172/JCI146922  0.312
2021 Hwang MS, Mog BJ, Douglass J, Pearlman AH, Hsiue EH, Paul S, DiNapoli SR, Konig MF, Pardoll DM, Gabelli SB, Bettegowda C, Papadopoulos N, Vogelstein B, Zhou S, Kinzler KW. Targeting loss of heterozygosity for cancer-specific immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33731480 DOI: 10.1073/pnas.2022410118  0.688
2021 Paul S, Pearlman AH, Douglass J, Mog BJ, Hsiue EH, Hwang MS, DiNapoli SR, Konig MF, Brown PA, Wright KM, Sur S, Gabelli SB, Li Y, Ghiaur G, Pardoll D, et al. TCR beta chain-directed bispecific antibodies for the treatment of T-cell cancers. Science Translational Medicine. PMID 33649188 DOI: 10.1126/scitranslmed.abd3595  0.825
2021 Hsiue EH, Wright KM, Douglass J, Hwang MS, Mog BJ, Pearlman AH, Paul S, DiNapoli SR, Konig MF, Wang Q, Schaefer A, Miller MS, Skora AD, Azurmendi PA, Murphy MB, ... ... Pardoll DM, et al. Targeting a neoantigen derived from a common mutation. Science (New York, N.Y.). PMID 33649166 DOI: 10.1126/science.abc8697  0.678
2021 Douglass J, Hsiue EH, Mog BJ, Hwang MS, DiNapoli SR, Pearlman AH, Miller MS, Wright KM, Azurmendi PA, Wang Q, Paul S, Schaefer A, Skora AD, Molin MD, Konig MF, ... ... Pardoll DM, et al. Bispecific antibodies targeting mutant neoantigens. Science Immunology. 6. PMID 33649101 DOI: 10.1126/sciimmunol.abd5515  0.652
2020 Anagnostou V, Bruhm DC, Niknafs N, White JR, Shao XM, Sidhom JW, Stein J, Tsai HL, Wang H, Belcaid Z, Murray J, Balan A, Ferreira L, Ross-Macdonald P, Wind-Rotolo M, ... ... Pardoll DM, et al. Integrative Tumor and Immune Cell Multi-omic Analyses Predict Response to Immune Checkpoint Blockade in Melanoma. Cell Reports. Medicine. 1: 100139. PMID 33294860 DOI: 10.1016/j.xcrm.2020.100139  0.339
2020 Faust HJ, Zhang H, Han J, Wolf MT, Jeon OH, Sadtler K, Peña AN, Chung L, Maestas DR, Tam AJ, Pardoll DM, Campisi J, Housseau F, Zhou D, Bingham CO, et al. IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis. The Journal of Clinical Investigation. PMID 32955487 DOI: 10.1172/Jci134091  0.388
2020 Grasso CS, Tsoi J, Onyshchenko M, Abril-Rodriguez G, Ross-Macdonald P, Wind-Rotolo M, Champhekar A, Medina E, Torrejon DY, Shin DS, Tran P, Kim YJ, Puig-Saus C, Campbell K, Vega-Crespo A, ... ... Pardoll DM, et al. Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma. Cancer Cell. PMID 32916126 DOI: 10.1016/J.Ccell.2020.08.005  0.402
2020 Theodros D, Murter BM, Sidhom JW, Nirschl TR, Clark DJ, Chen L, Tam A, Blosser RL, Schwen ZR, Johnson MH, Pierorazio PM, Zhang H, Ganguly S, Pardoll DM, Zarif JC. High-Dimensional Cytometry (ExCYT) and Mass Spectrometry of myeloid infiltrate in clinically localized clear cell Renal Cell Carcinoma identifies novel potential myeloid targets for immunotherapy. Molecular & Cellular Proteomics : McP. PMID 32737216 DOI: 10.1074/Mcp.Ra120.002049  0.39
2020 Chen L, Oke T, Siegel N, Cojocaru G, Tam AJ, Blosser RL, Swailes J, Ligon JA, Lebid A, Morris C, Levin A, Rhee DS, Johnston FM, Greer JB, Meyer CF, ... ... Pardoll DM, et al. The Immunosuppressive Niche of Soft Tissue Sarcomas is Sustained by Tumor Associated Macrophages and Characterized by Intratumoral Tertiary Lymphoid Structures. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32332015 DOI: 10.1158/1078-0432.Ccr-19-3416  0.319
2020 Lebid A, Chung L, Pardoll DM, Pan F. YAP Attenuates CD8 T Cell-Mediated Anti-tumor Response. Frontiers in Immunology. 11: 580. PMID 32322254 DOI: 10.3389/Fimmu.2020.00580  0.494
2020 Chung L, Maestas DR, Lebid A, Mageau A, Rosson GD, Wu X, Wolf MT, Tam AJ, Vanderzee I, Wang X, Andorko JI, Zhang H, Narain R, Sadtler K, Fan H, ... ... Pardoll DM, et al. Interleukin 17 and senescent cells regulate the foreign body response to synthetic material implants in mice and humans. Science Translational Medicine. 12. PMID 32295900 DOI: 10.1126/Scitranslmed.Aax3799  0.375
2020 Lipson EJ, Naqvi FF, Loss MJ, Schollenberger MD, Pardoll DM, Moore J, Brennan DC. Kidney retransplantation after anti-programmed cell death-1 (PD-1)-related allograft rejection. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 32185872 DOI: 10.1111/Ajt.15856  0.364
2020 Topalian SL, Taube JM, Pardoll DM. Neoadjuvant checkpoint blockade for cancer immunotherapy. Science (New York, N.Y.). 367. PMID 32001626 DOI: 10.1126/Science.Aax0182  0.322
2020 Kumar R, Boyapati K, Thomas N, Topiwala D, Kanacharoen S, Owoyemi O, Coffey M, Carducci M, Markowski MC, Antonarakis ES, Pardoll D, Denmeade S, Kachhap SK. Abstract 2410: Supraphysiological androgens induce ferroptotic cell death in prostate cancer cells Cancer Research. 80: 2410-2410. DOI: 10.1158/1538-7445.Am2020-2410  0.385
2019 Zhang J, Ji Z, Caushi JX, El Asmar M, Anagnostou V, Cottrell TR, Chan HY, Suri P, Guo H, Merghoub T, Chaft JE, Reuss JE, Tam AJ, Blosser RL, Abu-Akeel M, ... ... Pardoll DM, et al. Compartmental analysis of T cell clonal dynamics as a function of pathologic response to neoadjuvant PD-1 blockade in resectable non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31754049 DOI: 10.1158/1078-0432.Ccr-19-2931  0.396
2019 Chen S, Crabill GA, Pritchard TS, McMiller TL, Wei P, Pardoll DM, Pan F, Topalian SL. Mechanisms regulating PD-L1 expression on tumor and immune cells. Journal For Immunotherapy of Cancer. 7: 305. PMID 31730010 DOI: 10.1186/S40425-019-0770-2  0.362
2019 Stein JE, Lipson EJ, Cottrell TR, Forde PM, Anders RA, Cimino-Mathews A, Thompson ED, Allaf ME, Yarchoan M, Feliciano J, Wang H, Jaffee EM, Pardoll DM, Topalian SL, Taube JM. Pan-Tumor Pathologic Scoring of Response to PD-(L)1 Blockade. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31672770 DOI: 10.1158/1078-0432.Ccr-19-2379  0.338
2019 Sommerfeld SD, Cherry C, Schwab RM, Chung L, Maestas DR, Laffont P, Stein JE, Tam A, Ganguly S, Housseau F, Taube JM, Pardoll DM, Cahan P, Elisseeff JH. Interleukin-36γ-producing macrophages drive IL-17-mediated fibrosis. Science Immunology. 4. PMID 31604843 DOI: 10.1126/Sciimmunol.Aax4783  0.372
2019 Sokol ES, Pavlick D, Frampton GM, Ross JS, Miller VA, Ali SM, Lotan TL, Pardoll DM, Chung JH, Antonarakis ES. Pan-Cancer Analysis of Loss-of-Function Alterations and Their Association with the Focal Tandem-Duplicator Phenotype. The Oncologist. PMID 31292271 DOI: 10.1634/Theoncologist.2019-0214  0.335
2019 Smith KN, Llosa NJ, Cottrell TR, Siegel N, Fan H, Suri P, Chan HY, Guo H, Oke T, Awan AH, Verde F, Danilova L, Anagnostou V, Tam AJ, Luber BS, ... ... Pardoll DM, et al. Correction to: persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1 (Journal for Immuno Therapy of Cancer (2019) 7 (40) DOI: 10.1186/s40425-018-0492-x) Journal For Immunotherapy of Cancer. 7: 7. PMID 30841906 DOI: 10.1186/S40425_019_0547_7  0.52
2019 Smith KN, Llosa NJ, Cottrell TR, Siegel N, Fan H, Suri P, Chan HY, Guo H, Oke T, Awan AH, Verde F, Danilova L, Anagnostou V, Tam AJ, Luber BS, ... ... Pardoll DM, et al. Correction to: persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1. Journal For Immunotherapy of Cancer. 7: 63. PMID 30841906 DOI: 10.1186/S40425-019-0547-7  0.452
2019 Smith KN, Llosa NJ, Cottrell TR, Siegel N, Fan H, Suri P, Chan HY, Guo H, Oke T, Awan AH, Verde F, Danilova L, Anagnostou V, Tam AJ, Luber BS, ... ... Pardoll DM, et al. Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1. Journal For Immunotherapy of Cancer. 7: 40. PMID 30744692 DOI: 10.1186/S40425-018-0492-X  0.452
2019 Cheung LS, Fu J, Kumar P, Kumar A, Urbanowski ME, Ihms EA, Parveen S, Bullen CK, Patrick GJ, Harrison R, Murphy JR, Pardoll DM, Bishai WR. Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti-PD-1 in melanoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 30718426 DOI: 10.1073/Pnas.1815087116  0.347
2019 Wolf MT, Ganguly S, Wang TL, Anderson CW, Sadtler K, Narain R, Cherry C, Parrillo AJ, Park BV, Wang G, Pan F, Sukumar S, Pardoll DM, Elisseeff JH. A biologic scaffold-associated type 2 immune microenvironment inhibits tumor formation and synergizes with checkpoint immunotherapy. Science Translational Medicine. 11. PMID 30700576 DOI: 10.1126/Scitranslmed.Aat7973  0.448
2019 Murter B, Pan X, Ophir E, Alteber Z, Azulay M, Sen R, Levy O, Dassa L, Vaknin I, Fridman-Kfir T, Salomon R, Ravet A, Tam A, Levin D, Vaknin Y, ... ... Pardoll D, et al. Mouse PVRIG Has CD8 T Cell-Specific Coinhibitory Functions and Dampens Antitumor Immunity. Cancer Immunology Research. PMID 30659055 DOI: 10.1158/2326-6066.CIR-18-0460  0.409
2019 Whelan S, Ophir E, Kotturi MF, Levy O, Ganguly S, Leung L, Vaknin I, Kumar S, Dassa L, Hansen K, Bernados D, Murter B, Soni A, Taube JM, Fader AN, ... ... Pardoll DM, et al. PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8 T-cell Function. Cancer Immunology Research. PMID 30659054 DOI: 10.1158/2326-6066.Cir-18-0442  0.633
2019 Mendonca J, Owoyemi O, Rosen M, Carducci M, Markowski M, Antonarakis E, Pardoll D, Denmeade S, Kachhap SK. Abstract 517: Supraphysiological androgens activate innate immune signaling in prostate cancer Immunology. DOI: 10.1158/1538-7445.Sabcs18-517  0.312
2019 Ligon JA, Oke TF, Choi W, Fong MH, Levin A, Rhee DS, Morris CD, Siegel N, Hsieu EH, Meyer CF, McConkey DJ, Anders RA, Pardoll DM, Llosa NJ. Abstract 4973: The immunosuppressive tumor microenvironment of metastatic osteosarcoma inhibits the cytotoxic effect of tumor-infiltrating lymphocytes Immunology. DOI: 10.1158/1538-7445.Sabcs18-4973  0.361
2019 Llosa N, Awan AH, Tam AJ, Fan H, Smith KN, Sears CL, Wang H, Pardoll DM, Anders RA, Housseau F. Abstract 2793: Mismatch repair proficient colorectal cancer and adaptive immunosuppression of endogenous anti-tumor immune response: Implications for immunotherapy Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2793  0.385
2019 Sloan L, Sen R, Doucet M, Blosser L, Shpitser I, Sherman E, San N, Cheng Z, Katulis L, Wemmer J, Kamson D, Jackson C, Hu C, McNutt T, Grossman S, ... ... Pardoll D, et al. RTHP-43 (LTBK-02). MULTI-TIME POINT EVALUATION OF PERIPHERAL BLOOD MYELOID-DERIVED SUPPRESSOR CELL AND LYMPHOCYTE POPULATIONS IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA RECEIVING ADJUVANT THERAPY Neuro-Oncology. 21: vi283-vi283. DOI: 10.1093/Neuonc/Noz219.1196  0.342
2019 Jackson C, Choi J, Zhang J, Piotrowski A, Walbert T, Desai A, Ahluwalia M, Nabors B, Ye X, Desideri S, Fisher J, Wen P, Grossman S, Smith K, Pardoll D, et al. IMMU-18. IMMUNOGENOMIC RESPONDER PHENOTYPE FROM A PHASE I TRIAL OF ANTI-LAG3 OR ANTI-CD137 ALONE AND IN COMBINATION WITH ANTI-PD-1 IN PATIENTS WITH RECURRENT GBM Neuro-Oncology. 21: vi122-vi123. DOI: 10.1093/Neuonc/Noz175.511  0.448
2019 Caushi J, Ji Z, Zhang J, Asmar ME, Anagnostou V, Cottrell T, Chan HY, Guo H, Merghoub T, Wolchok J, Naidoo J, Marrone K, Chaft J, Hellmann M, Gabrielson E, ... ... Pardoll D, et al. P2.04-24 Transcriptional Profiling of Neoantigen Specific T Cells in Resectable NSCLC Treated with Neoadjuvant Anti-PD-1 Journal of Thoracic Oncology. 14. DOI: 10.1016/J.Jtho.2019.08.1529  0.36
2018 Anagnostou V, Forde PM, White JR, Niknafs N, Hruban C, Naidoo J, Marrone KA, Sivakumar IKA, Bruhm DC, Rosner S, Phallen J, Leal A, Adleff V, Smith KN, Cottrell TR, ... ... Pardoll DM, et al. Dynamics of tumor and immune responses during immune checkpoint blockade in non-small cell lung cancer. Cancer Research. PMID 30541742 DOI: 10.1158/0008-5472.Can-18-1127  0.41
2018 Sadtler K, Wolf MT, Ganguly S, Moad CA, Chung L, Majumdar S, Housseau F, Pardoll DM, Elisseeff JH. Divergent immune responses to synthetic and biological scaffolds. Biomaterials. 192: 405-415. PMID 30500722 DOI: 10.1016/J.Biomaterials.2018.11.002  0.317
2018 Hung AL, Maxwell R, Theodros D, Belcaid Z, Mathios D, Luksik AS, Kim E, Wu A, Xia Y, Garzon-Muvdi T, Jackson C, Ye X, Tyler B, Selby M, Korman A, ... ... Pardoll DM, et al. TIGIT and PD-1 dual checkpoint blockade enhances antitumor immunity and survival in GBM. Oncoimmunology. 7: e1466769. PMID 30221069 DOI: 10.1080/2162402X.2018.1466769  0.358
2018 Ni X, Tao J, Barbi J, Chen Q, Park BV, Li Z, Zhang N, Lebid A, Ramaswamy A, Wei P, Zheng Y, Zhang X, Wu X, Vignali PDA, Yang C, ... ... Pardoll D, et al. YAP is essential for Treg mediated suppression of anti-tumor immunity. Cancer Discovery. PMID 29907586 DOI: 10.1158/2159-8290.Cd-17-1124  0.452
2018 Danilova L, Anagnostou V, Caushi JX, Sidhom JW, Guo H, Chan HY, Suri P, Tam AJ, Zhang J, El Asmar M, Marrone KA, Naidoo J, Brahmer JR, Forde PM, Baras AS, ... ... Pardoll D, et al. The Mutation-Associated Neoantigen Functional Expansion of Specific T cells (MANAFEST) assay: a sensitive platform for monitoring antitumor immunity. Cancer Immunology Research. PMID 29895573 DOI: 10.1158/2326-6066.Cir-18-0129  0.461
2018 Garzon-Muvdi T, Theodros D, Luksik AS, Maxwell R, Kim E, Jackson CM, Belcaid Z, Ganguly S, Tyler B, Brem H, Pardoll DM, Lim M. Dendritic cell activation enhances anti-PD-1 mediated immunotherapy against glioblastoma. Oncotarget. 9: 20681-20697. PMID 29755681 DOI: 10.18632/Oncotarget.25061  0.389
2018 Forde PM, Chaft JE, Smith KN, Anagnostou V, Cottrell TR, Hellmann MD, Zahurak M, Yang SC, Jones DR, Broderick S, Battafarano RJ, Velez MJ, Rekhtman N, Olah Z, Naidoo J, ... ... Pardoll DM, et al. Neoadjuvant PD-1 Blockade in Resectable Lung Cancer. The New England Journal of Medicine. PMID 29658848 DOI: 10.1056/Nejmoa1716078  0.395
2018 Zeng Q, Fu J, Korrer M, Gorbounov M, Murray PJ, Pardoll DM, Masica DL, Kim YJ. Caspase-1 from Human Myeloid Derived Suppressor Cells Can Promote T-cell independent Tumor Proliferation. Cancer Immunology Research. PMID 29653983 DOI: 10.1158/2326-6066.Cir-17-0543  0.436
2018 Francica BJ, Ghasemzadeh A, Desbien AL, Theodros D, Sivick KE, Reiner GL, Hix Glickman L, Marciscano AE, Sharabi AB, Leong ML, McWhirter SM, Dubensky TW, Pardoll DM, Drake CG. TNFalpha and radio-resistant stromal cells are essential for therapeutic efficacy of cyclic dinucleotide STING agonists in non-immunogenic tumors. Cancer Immunology Research. PMID 29472271 DOI: 10.1158/2326-6066.Cir-17-0263  0.436
2018 Cottrell TR, Stein JE, Chaft JE, Thompson ED, Rekhtman N, Anagnostou V, Smith KN, Duffield AS, Anders RA, Isbell JM, Jones DR, Cuda JD, Battafarano R, Yang SC, Illei PB, ... ... Pardoll DM, et al. Abstract LB-154: Pathologic features of response to neoadjuvant anti-PD-1 in resected non-small cell lung carcinoma (NSCLC): A proposal for quantitative immune-related pathologic response criteria (irPRC) Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-154  0.363
2018 Wu A, Cardarelli P, Oyasu M, Menezes D, Ponath P, Cogswell J, Maxwell R, Luksik A, Hung A, Kim E, Belcaid Z, Brem H, Pardoll D, Lim M. Abstract 1736: The combination of CXCR4 and checkpoint receptor inhibition improves survival in an orthotopic murine glioma model Cancer Research. 78: 1736-1736. DOI: 10.1158/1538-7445.Am2018-1736  0.415
2018 Domingue JC, Llosa N, White J, Drewes JL, Craig C, Tomkovich SE, Jobin C, Ding H, Tam A, Pardoll D, Housseau F, Sears CL. 151 - Colonic Bacteria and the Tumor Immune Microenvironment of Colorectal Cancer Patients Gastroenterology. 154. DOI: 10.1016/S0016-5085(18)30609-7  0.363
2018 Maxwell R, Luksik A, Garzon-Muvdi T, Hung AL, Kim ES, Wu A, Xia Y, Belcaid Z, Gorelick N, Theodros D, Jackson C, Ye X, Tran PT, Redmond KJ, Brem H, ... Pardoll DM, et al. Impact of Corticosteroids on the Efficacy of Anti-PD-1 Therapy for Tumors Located Within or Outside the Central Nervous System International Journal of Radiation Oncology Biology Physics. 102. DOI: 10.1016/J.Ijrobp.2018.07.035  0.307
2017 Duffield AS, Ascierto ML, Anders RA, Taube JM, Meeker AK, Chen S, McMiller TL, Phillips NA, Xu H, Ogurtsova A, Berger AE, Pardoll DM, Topalian SL, Ambinder RF. Th17 immune microenvironment in Epstein-Barr virus-negative Hodgkin lymphoma: implications for immunotherapy. Blood Advances. 1: 1324-1334. PMID 29296775 DOI: 10.1182/Bloodadvances.2017007260  0.316
2017 Wilson DR, Sen R, Sunshine JC, Pardoll DM, Green JJ, Kim YJ. Biodegradable STING agonist nanoparticles for enhanced cancer immunotherapy. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 29127039 DOI: 10.1016/J.Nano.2017.10.013  0.363
2017 Muroyama Y, Nirschl TR, Kochel CM, Lopez-Bujanda Z, Theodros D, Mao W, Carrera-Haro MA, Ghasemzadeh A, Marciscano AE, Velarde E, Tam AJ, Thoburn CJ, Uddin M, Meeker AK, Anders RA, ... Pardoll DM, et al. Stereotactic radiotherapy increases functionally suppressive regulatory T cells in the tumor microenvironment. Cancer Immunology Research. PMID 28970196 DOI: 10.1158/2326-6066.Cir-17-0040  0.452
2017 Le DT, Durham JN, Smith KN, Wang H, Bartlett BR, Aulakh LK, Lu S, Kemberling H, Wilt C, Luber BS, Wong F, Azad NS, Rucki AA, Laheru D, Donehower R, ... ... Pardoll DM, et al. Mismatch-repair deficiency predicts response of solid tumors to PD-1 blockade. Science (New York, N.Y.). PMID 28596308 DOI: 10.1126/Science.Aan6733  0.49
2017 Chiappinelli KB, Strissel PL, Desrichard A, Li H, Henke C, Akman B, Hein A, Rote NS, Cope LM, Snyder A, Makarov V, Budhu S, Slamon DJ, Wolchok JD, Pardoll DM, et al. Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses. Cell. 169: 361. PMID 28388418 DOI: 10.1016/J.Cell.2017.03.036  0.487
2017 Ascierto ML, Makohon-Moore A, Lipson EJ, Taube JM, McMiller TL, Berger AE, Fan J, Kaunitz G, Cottrell T, Kohutek Z, Favorov A, Makarov V, Riaz N, Chan TA, Cope L, ... ... Pardoll DM, et al. Transcriptional mechanisms of resistance to anti-PD-1 therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28193624 DOI: 10.1158/1078-0432.Ccr-17-0270  0.486
2017 Anagnostou V, Smith KN, Forde PM, Niknafs N, Bhattacharya R, White J, Adleff V, Phallen J, Wali N, Hruban C, Guthrie VB, Rodgers K, Naidoo J, Kang H, Sharfman W, ... ... Pardoll DM, et al. Abstract NG01: Evolution of neoantigen landscape during immune checkpoint blockade in non-small cell lung cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Ng01  0.337
2017 Fu J, Sen R, Masica DL, Karchin R, Pardoll D, Kim Y. Abstract 3843: Autologous resconstitution of human cancer and immune system in vivo Cancer Research. 77: 3843-3843. DOI: 10.1158/1538-7445.Am2017-3843  0.34
2016 Anagnostou V, Smith KN, Forde PM, Niknafs N, Bhattacharya R, White J, Zhang T, Adleff V, Phallen J, Wali N, Hruban C, Guthrie VB, Rodgers K, Naidoo J, Kang H, ... ... Pardoll DM, et al. Evolution of Neoantigen Landscape During Immune Checkpoint Blockade in Non-Small Cell Lung Cancer. Cancer Discovery. PMID 28031159 DOI: 10.1158/2159-8290.Cd-16-0828  0.462
2016 Fu J, Sen R, Masica DL, Karchin R, Pardoll D, Walter V, Hayes DN, Chung CH, Kim YJ. Autologous reconstitution of human cancer and immune system in vivo. Oncotarget. PMID 28008146 DOI: 10.18632/Oncotarget.14026  0.301
2016 Mathios D, Kim JE, Mangraviti A, Phallen J, Park CK, Jackson CM, Garzon-Muvdi T, Kim E, Theodros D, Polanczyk M, Martin AM, Suk I, Ye X, Tyler B, Bettegowda C, ... ... Pardoll DM, et al. Anti-PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM. Science Translational Medicine. 8: 370ra180. PMID 28003545 DOI: 10.1126/Scitranslmed.Aag2942  0.443
2016 Danilova L, Wang H, Sunshine J, Kaunitz GJ, Cottrell TR, Xu H, Esandrio J, Anders RA, Cope L, Pardoll DM, Drake CG, Taube JM. Association of PD-1/PD-L axis expression with cytolytic activity, mutational load, and prognosis in melanoma and other solid tumors. Proceedings of the National Academy of Sciences of the United States of America. PMID 27837027 DOI: 10.1073/Pnas.1607836113  0.309
2016 Sadtler K, Allen BW, Estrellas K, Housseau F, Pardoll DM, Elisseeff JH. The Scaffold Immune Microenvironment: Biomaterial-Mediated Immune Polarization in Traumatic and Non-Traumatic Applications. Tissue Engineering. Part A. PMID 27736323 DOI: 10.1089/Ten.Tea.2016.0304  0.38
2016 Park BV, Freeman ZT, Ghasemzadeh A, Chattergoon MA, Rutebemberwa A, Steigner J, Winter ME, Huynh TV, Sebald SM, Lee SJ, Pan F, Pardoll DM, Cox AL. TGF-β1-Mediated Smad3 Enhances PD-1 Expression on Antigen-Specific T Cells in Cancer. Cancer Discovery. PMID 27683557 DOI: 10.1158/2159-8290.Cd-15-1347  0.428
2016 Ascierto ML, McMiller TL, Berger AE, Danilova L, Anders RA, Netto GJ, Xu H, Pritchard TS, Fan J, Cheadle C, Cope L, Drake CG, Pardoll DM, Taube JM, Topalian SL. The Intratumoral Balance between Metabolic and Immunologic Gene Expression Is Associated with Anti-PD-1 Response in Patients with Renal Cell Carcinoma. Cancer Immunology Research. PMID 27491898 DOI: 10.1158/2326-6066.Cir-16-0072  0.362
2016 Yang HY, Barbi J, Wu CY, Zheng Y, Vignali PD, Wu X, Tao JH, Park BV, Bandara S, Novack L, Ni X, Yang X, Chang KY, Wu RC, Zhang J, ... ... Pardoll DM, et al. MicroRNA-17 Modulates Regulatory T Cell Function by Targeting Co-regulators of the Foxp3 Transcription Factor. Immunity. 45: 83-93. PMID 27438767 DOI: 10.1016/J.Immuni.2016.06.022  0.331
2016 Patel MA, Kim JE, Theodros D, Tam A, Velarde E, Kochel CM, Francica B, Nirschl TR, Ghasemzadeh A, Mathios D, Harris-Bookman S, Jackson CC, Jackson C, Ye X, Tran PT, ... ... Pardoll DM, et al. Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma. Journal For Immunotherapy of Cancer. 4: 28. PMID 27190629 DOI: 10.1186/S40425-016-0132-2  0.384
2016 Sadtler K, Estrellas K, Allen BW, Wolf MT, Fan H, Tam AJ, Patel CH, Luber BS, Wang H, Wagner KR, Powell JD, Housseau F, Pardoll DM, Elisseeff JH. Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells. Science (New York, N.Y.). 352: 366-70. PMID 27081073 DOI: 10.1126/Science.Aad9272  0.332
2016 Chiappinelli KB, Strissel PL, Desrichard A, Li H, Henke C, Akman B, Hein A, Rote NS, Cope LM, Snyder A, Makarov V, Budhu S, Slamon DJ, Wolchok JD, Pardoll DM, et al. Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses. Cell. 164: 1073. PMID 27064190 DOI: 10.1016/J.Cell.2015.10.020  0.487
2016 Lipson EJ, Bagnasco SM, Moore J, Jang S, Patel MJ, Zachary AA, Pardoll DM, Taube JM, Drake CG. Tumor Regression and Allograft Rejection after Administration of Anti-PD-1. The New England Journal of Medicine. 374: 896-898. PMID 26962927 DOI: 10.1056/Nejmc1509268  0.301
2016 Housseau F, Wu S, Wick EC, Fan H, Wu X, Llosa NJ, Smith KN, Tam A, Ganguly S, Wanyiri JW, Iyadorai T, Malik AA, Roslani AC, Vadivelu JS, Van Meerbeke S, ... ... Pardoll DM, et al. Redundant innate and adaptive sources of IL-17 production drive colon tumorigenesis. Cancer Research. PMID 26880802 DOI: 10.1158/0008-5472.Can-15-0749  0.404
2016 Forde PM, Smith K, Chaft JE, Hellmann MD, Merghoub T, Wolchok JD, Yang SC, Battafarano RJ, Gabrielson E, Georgiades C, Verde F, Rosner GL, Anagnostou V, Velculescu VE, Topalian SL, ... Pardoll DM, et al. Neoadjuvant anti-PD1, nivolumab, in early stage resectable non-small-cell lung cancer. Journal of Clinical Oncology. 34: e20005-e20005. DOI: 10.1200/Jco.2016.34.15_Suppl.E20005  0.318
2016 Llosa NJ, Housseau F, Wick E, Lizzy H, Cruise M, Anders R, Sears C, Pardoll DM, Fan H, Siegel N, Blosser L, Tam A, Wang H. Abstract A141: The vigorous immune microenvironment of microsatellite instable colon cancer isbalanced by multiple counter-inhibitory checkpoints Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A141  0.443
2016 Zeng Q, Qualliotine JR, Blosser L, Pardoll D, Kim YJ. Abstract 3250: Caspase-1 from MDSC promote MyD88 dependent carcinogenesis that is T-cell independent Cancer Research. 76: 3250-3250. DOI: 10.1158/1538-7445.Am2016-3250  0.495
2015 Pardoll D. Cancer and the Immune System: Basic Concepts and Targets for Intervention Seminars in Oncology. 42: 523-538. PMID 26320058 DOI: 10.1053/J.Seminoncol.2015.05.003  0.475
2015 Chiappinelli KB, Strissel PL, Desrichard A, Li H, Henke C, Akman B, Hein A, Rote NS, Cope LM, Snyder A, Makarov V, Buhu S, Slamon DJ, Wolchok JD, Pardoll DM, et al. Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses. Cell. 162: 974-86. PMID 26317466 DOI: 10.1016/J.Cell.2015.07.011  0.496
2015 Geis AL, Fan H, Wu X, Wu S, Huso DL, Wolfe JL, Sears CL, Pardoll DM, Housseau F. Regulatory T cell response to enterotoxigenic Bacteroides fragilis colonization triggers IL-17-dependent colon carcinogenesis. Cancer Discovery. PMID 26201900 DOI: 10.1158/2159-8290.Cd-15-0447  0.359
2015 Kim JE, Patel MA, Mangraviti A, Velarde E, Theodros D, Mathios D, Jackson CM, Tyler B, Ye X, Brem H, Pardoll D, Lim M. 143 The Combination of anti-TIM-3 and anti-PD-1 Checkpoint Inhibitors With Focused Radiation Resulted in a Synergistic Antitumor Immune Response in a Preclinical Glioma Model. Neurosurgery. 62: 212. PMID 26181989 DOI: 10.1227/01.Neu.0000467105.60300.04  0.316
2015 Mathios D, Park CK, Marcus WD, Alter S, Rhode PR, Jeng EK, Wong HC, Pardoll DM, Lim M. Therapeutic administration of IL-15 superagonist complex ALT-803 leads to long-term survival and durable antitumor immune response in a murine glioblastoma model. International Journal of Cancer. Journal International Du Cancer. PMID 26174883 DOI: 10.1002/Ijc.29686  0.438
2015 Lipson EJ, Sharfman WH, Chen S, McMiller TL, Pritchard TS, Salas JT, Sartorius-Mergenthaler S, Freed I, Ravi S, Wang H, Luber B, Sproul JD, Taube JM, Pardoll DM, Topalian SL. Safety and immunologic correlates of Melanoma GVAX, a GM-CSF secreting allogeneic melanoma cell vaccine administered in the adjuvant setting. Journal of Translational Medicine. 13: 214. PMID 26143264 DOI: 10.1186/S12967-015-0572-3  0.337
2015 Apetoh L, Smyth MJ, Drake CG, Abastado JP, Apte RN, Ayyoub M, Blay JY, Bonneville M, Butterfield LH, Caignard A, Castelli C, Cavallo F, Celis E, Chen L, Colombo MP, ... ... Pardoll DM, et al. Consensus nomenclature for CD8(+) T cell phenotypes in cancer. Oncoimmunology. 4: e998538. PMID 26137416 DOI: 10.1080/2162402X.2014.998538  0.379
2015 Barbi J, Pardoll DM, Pan F. Ubiquitin-dependent regulation of Foxp3 and Treg function. Immunological Reviews. 266: 27-45. PMID 26085205 DOI: 10.1111/Imr.12312  0.366
2015 Patel MA, Pardoll DM. Concepts of immunotherapy for glioma. Journal of Neuro-Oncology. 123: 323-30. PMID 26070552 DOI: 10.1007/S11060-015-1810-5  0.386
2015 Le DT, Uram JN, Wang H, Bartlett BR, Kemberling H, Eyring AD, Skora AD, Luber BS, Azad NS, Laheru D, Biedrzycki B, Donehower RC, Zaheer A, Fisher GA, Crocenzi TS, ... ... Pardoll DM, et al. PD-1 Blockade in Tumors with Mismatch-Repair Deficiency. The New England Journal of Medicine. 372: 2509-20. PMID 26028255 DOI: 10.1200/Jco.2015.33.18_Suppl.Lba100  0.444
2015 Mascanfroni ID, Takenaka MC, Yeste A, Patel B, Wu Y, Kenison JE, Siddiqui S, Basso AS, Otterbein LE, Pardoll DM, Pan F, Priel A, Clish CB, Robson SC, Quintana FJ. Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α. Nature Medicine. 21: 638-46. PMID 26005855 DOI: 10.1038/Nm.3868  0.376
2015 Noonan KA, Huff CA, Davis J, Lemas MV, Fiorino S, Bitzan J, Ferguson A, Emerling A, Luznik L, Matsui W, Powell J, Fuchs E, Rosner GL, Epstein C, Rudraraju L, ... ... Pardoll D, et al. Adoptive transfer of activated marrow-infiltrating lymphocytes induces measurable antitumor immunity in the bone marrow in multiple myeloma. Science Translational Medicine. 7: 288ra78. PMID 25995224 DOI: 10.1126/Scitranslmed.Aaa7014  0.448
2015 Taube JM, Young GD, McMiller TL, Chen S, Salas JT, Pritchard TS, Xu H, Meeker AK, Fan J, Cheadle C, Berger AE, Pardoll DM, Topalian SL. Differential expression of immune-regulatory genes associated with PD-L1 display in melanoma: implications for PD-1 pathway blockade. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 25944800 DOI: 10.1158/1078-0432.Ccr-15-0244  0.319
2015 Pardoll DM. Distinct mechanisms of tumor resistance to NK killing: of mice and men. Immunity. 42: 605-6. PMID 25902479 DOI: 10.1016/J.Immuni.2015.04.007  0.364
2015 Fu J, Kanne DB, Leong M, Glickman LH, McWhirter SM, Lemmens E, Mechette K, Leong JJ, Lauer P, Liu W, Sivick KE, Zeng Q, Soares KC, Zheng L, Portnoy DA, ... ... Pardoll DM, et al. STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade. Science Translational Medicine. 7: 283ra52. PMID 25877890 DOI: 10.1126/Scitranslmed.Aaa4306  0.481
2015 Llosa NJ, Cruise M, Tam A, Wicks EC, Hechenbleikner EM, Taube JM, Blosser RL, Fan H, Wang H, Luber BS, Zhang M, Papadopoulos N, Kinzler KW, Vogelstein B, Sears CL, ... ... Pardoll DM, et al. The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints. Cancer Discovery. 5: 43-51. PMID 25358689 DOI: 10.1158/2159-8290.Cd-14-0863  0.594
2015 Mathios D, Ruzevick J, Jackson CM, Xu H, Shah S, Taube JM, Burger PC, McCarthy EF, Quinones-Hinojosa A, Pardoll DM, Lim M. PD-1, PD-L1, PD-L2 expression in the chordoma microenvironment. Journal of Neuro-Oncology. 121: 251-9. PMID 25349132 DOI: 10.1007/S11060-014-1637-5  0.335
2015 Overacre AE, Kurtulus S, Sznol M, Pardoll DM, Anderson A, Vignali DAA. Combination immunotherapy: Where do we go from here? Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/S40425-015-0083-Z  0.371
2015 Zeng Q, Qualliotine J, Blosser R, Pardoll D, Kim Y. MDSCs enhance tumor cell proliferation in a caspase-1 related inflammasome cytokines dependent way Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P317  0.476
2015 Mathios D, Kim J, Phallen J, Mangraviti A, Park C, Theodros D, Jackson C, Garzon-Muvdi T, Kim E, Ye X, Tyler B, Brem H, Pardoll D, Lim M. Optimizing the delivery of chemotherapy in the setting of immunotherapy in a preclinical glioblastoma model Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P307  0.328
2015 Llosa NJ, Cruise M, Tam A, Wick E, Hechenbleikner E, Taube J, Blosser L, Fan H, Wang H, Zhang M, Luber B, Papadopoulos N, Kinzler K, Vogelstein B, Sears C, ... ... Pardoll D, et al. Abstract 451: The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints Cancer Research. 75: 451-451. DOI: 10.1158/1538-7445.Am2015-451  0.495
2015 Orberg ET, Fan H, Tam A, Wu S, Wu X, Ganguly S, Pardoll DM, Sears CL, Housseau F. 103 The myeloid immune signature of enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis European Journal of Cancer. 51. DOI: 10.1016/S0959-8049(16)30003-X  0.32
2014 Lipson EJ, Velculescu VE, Pritchard TS, Sausen M, Pardoll DM, Topalian SL, Diaz LA. Circulating tumor DNA analysis as a real-time method for monitoring tumor burden in melanoma patients undergoing treatment with immune checkpoint blockade. Journal For Immunotherapy of Cancer. 2: 42. PMID 25516806 DOI: 10.1186/S40425-014-0042-0  0.377
2014 Dejea CM, Wick EC, Hechenbleikner EM, White JR, Mark Welch JL, Rossetti BJ, Peterson SN, Snesrud EC, Borisy GG, Lazarev M, Stein E, Vadivelu J, Roslani AC, Malik AA, Wanyiri JW, ... ... Pardoll DM, et al. Microbiota organization is a distinct feature of proximal colorectal cancers. Proceedings of the National Academy of Sciences of the United States of America. 111: 18321-6. PMID 25489084 DOI: 10.1073/Pnas.1406199111  0.43
2014 Belcaid Z, Phallen JA, Zeng J, See AP, Mathios D, Gottschalk C, Nicholas S, Kellett M, Ruzevick J, Jackson C, Albesiano E, Durham NM, Ye X, Tran PT, Tyler B, ... ... Pardoll DM, et al. Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model. Plos One. 9: e101764. PMID 25013914 DOI: 10.1371/Journal.Pone.0101764  0.447
2014 Zheng L, Edil BH, Soares KC, El-Shami K, Uram JN, Judkins C, Zhang Z, Onners B, Laheru D, Pardoll D, Jaffee EM, Schulick RD. A safety and feasibility study of an allogeneic colon cancer cell vaccine administered with a granulocyte-macrophage colony stimulating factor-producing bystander cell line in patients with metastatic colorectal cancer. Annals of Surgical Oncology. 21: 3931-7. PMID 24943235 DOI: 10.1245/S10434-014-3844-X  0.392
2014 Fu J, Malm IJ, Kadayakkara DK, Levitsky H, Pardoll D, Kim YJ. Preclinical evidence that PD1 blockade cooperates with cancer vaccine TEGVAX to elicit regression of established tumors. Cancer Research. 74: 4042-52. PMID 24812273 DOI: 10.1158/0008-5472.Can-13-2685  0.461
2014 Pardoll D. Immunotherapy: It Takes a Village Science. 344: 149-149. PMID 24723594 DOI: 10.1126/Science.344.6180.149-A  0.461
2014 Barbi J, Pardoll D, Pan F. Treg functional stability and its responsiveness to the microenvironment. Immunological Reviews. 259: 115-39. PMID 24712463 DOI: 10.1111/Imr.12172  0.367
2014 Wick EC, Rabizadeh S, Albesiano E, Wu X, Wu S, Chan J, Rhee KJ, Ortega G, Huso DL, Pardoll D, Housseau F, Sears CL. Stat3 activation in murine colitis induced by enterotoxigenic Bacteroides fragilis. Inflammatory Bowel Diseases. 20: 821-34. PMID 24704822 DOI: 10.1097/Mib.0000000000000019  0.395
2014 Li H, Chiappinelli KB, Guzzetta AA, Easwaran H, Yen RW, Vatapalli R, Topper MJ, Luo J, Connolly RM, Azad NS, Stearns V, Pardoll DM, Davidson N, Jones PA, Slamon DJ, et al. Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers. Oncotarget. 5: 587-98. PMID 24583822 DOI: 10.18632/Oncotarget.1782  0.398
2014 Lipson EJ, Sharfman WH, Chen S, McMiller TL, Pritchard TS, Salas JT, Sartorius-Mergenthaler S, Ravi S, Wang H, Taube JM, Pardoll DM, Topalian SL. Safety and immunologic correlates of allogeneic melanoma GVAX (MelGVAX), a genetically engineered whole-cell melanoma vaccine. Journal of Clinical Oncology. 32. DOI: 10.1200/Jco.2014.32.15_Suppl.E20001  0.345
2014 Llosa NJ, Housseau F, Wick EC, Hechenbleikner L, Cruise M, Anders R, Sears C, Pardoll DM. Immune checkpoints expression in MSI versus MSS colorectal cancers and their potential therapeutic implications. Journal of Clinical Oncology. 32: 3620-3620. DOI: 10.1200/Jco.2014.32.15_Suppl.3620  0.306
2014 Fu J, Pardoll D, Kim YJ. Cyclic dinucleotides (CDNs) anti-tumors response by activating DC and NK cell crosstalk Journal For Immunotherapy of Cancer. 2. DOI: 10.1186/2051-1426-2-S3-P169  0.425
2014 Glickman LH, Kanne DB, McWhirter SM, Leong ML, Lemmens EE, Metchette K, Vance RE, Pardoll DM, Dubensky TW. Abstract 2566: Activation of tumor-initiated T cell priming and tumor destruction with potent STING-activating cyclic dinucleotide derivatives Cancer Research. 74: 2566-2566. DOI: 10.1158/1538-7445.Am2014-2566  0.462
2014 Mathios D, Phallen J, Park C, Jackson C, Nicholas S, Tyler B, Pardoll D, Brem H, Lim M. It-21Pd-1 Blockade Shows Synergistic Survival, Anti-Tumor Immune Response And Long-Term Memory With Interstitial But Not Systemic Chemotherapy: Study In A Murine Glioblastoma Model. Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou258.19  0.327
2013 Wada S, Harris TJ, Tryggestad E, Yoshimura K, Zeng J, Yen HR, Getnet D, Grosso JF, Bruno TC, De Marzo AM, Netto GJ, Pardoll DM, DeWeese TL, Wong J, Drake CG. Combined treatment effects of radiation and immunotherapy: studies in an autochthonous prostate cancer model. International Journal of Radiation Oncology, Biology, Physics. 87: 769-76. PMID 24064321 DOI: 10.1016/J.Ijrobp.2013.07.015  0.636
2013 Chen Z, Barbi J, Bu S, Yang HY, Li Z, Gao Y, Jinasena D, Fu J, Lin F, Chen C, Zhang J, Yu N, Li X, Shan Z, Nie J, ... ... Pardoll DM, et al. The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3. Immunity. 39: 272-85. PMID 23973223 DOI: 10.1016/J.Immuni.2013.08.006  0.445
2013 Sharma MD, Huang L, Choi JH, Lee EJ, Wilson JM, Lemos H, Pan F, Blazar BR, Pardoll DM, Mellor AL, Shi H, Munn DH. An inherently bifunctional subset of Foxp3+ T helper cells is controlled by the transcription factor eos. Immunity. 38: 998-1012. PMID 23684987 DOI: 10.1016/J.Immuni.2013.01.013  0.429
2013 Wada S, Jackson CM, Yoshimura K, Yen HR, Getnet D, Harris TJ, Goldberg MV, Bruno TC, Grosso JF, Durham N, Netto GJ, Pardoll DM, Drake CG. Sequencing CTLA-4 blockade with cell-based immunotherapy for prostate cancer. Journal of Translational Medicine. 11: 89. PMID 23557194 DOI: 10.1186/1479-5876-11-89  0.779
2013 Zeng J, See AP, Phallen J, Jackson CM, Belcaid Z, Ruzevick J, Durham N, Meyer C, Harris TJ, Albesiano E, Pradilla G, Ford E, Wong J, Hammers HJ, Mathios D, ... ... Pardoll D, et al. Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas. International Journal of Radiation Oncology, Biology, Physics. 86: 343-9. PMID 23462419 DOI: 10.1016/J.Ijrobp.2012.12.025  0.67
2013 Vasquez-Dunddel D, Pan F, Zeng Q, Gorbounov M, Albesiano E, Fu J, Blosser RL, Tam AJ, Bruno T, Zhang H, Pardoll D, Kim Y. STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients. The Journal of Clinical Investigation. 123: 1580-9. PMID 23454751 DOI: 10.1172/Jci60083  0.436
2013 Kang TH, Mao CP, Lee SY, Chen A, Lee JH, Kim TW, Alvarez RD, Roden RB, Pardoll D, Hung CF, Wu TC. Chemotherapy acts as an adjuvant to convert the tumor microenvironment into a highly permissive state for vaccination-induced antitumor immunity. Cancer Research. 73: 2493-504. PMID 23418322 DOI: 10.1158/0008-5472.CAN-12-4241  0.371
2013 Barbi J, Pardoll D, Pan F. Metabolic control of the Treg/Th17 axis. Immunological Reviews. 252: 52-77. PMID 23405895 DOI: 10.1111/Imr.12029  0.414
2013 Lyford-Pike S, Peng S, Young GD, Taube JM, Westra WH, Akpeng B, Bruno TC, Richmon JD, Wang H, Bishop JA, Chen L, Drake CG, Topalian SL, Pardoll DM, Pai SI. Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma. Cancer Research. 73: 1733-41. PMID 23288508 DOI: 10.1158/0008-5472.Can-12-2384  0.559
2013 McAllister F, Bailey JM, Alsina J, Nirschl C, Roeser J, Blake D, Lankapali R, Sears C, Jaffee EM, Kolls J, Drake CG, Pardoll DM, Leach SD. TH17 cells and early pancreatic tumorigenesis. Journal of Clinical Oncology. 31: 144-144. DOI: 10.1200/Jco.2013.31.4_Suppl.144  0.372
2012 Pardoll DM. Immunology beats cancer: a blueprint for successful translation. Nature Immunology. 13: 1129-32. PMID 23160205 DOI: 10.1038/Ni.2392  0.321
2012 See AP, Han JE, Phallen J, Binder Z, Gallia G, Pan F, Jinasena D, Jackson C, Belcaid Z, Jeong SJ, Gottschalk C, Zeng J, Ruzevick J, Nicholas S, Kim Y, ... ... Pardoll DM, et al. The role of STAT3 activation in modulating the immune microenvironment of GBM. Journal of Neuro-Oncology. 110: 359-68. PMID 23096132 DOI: 10.1007/S11060-012-0981-6  0.386
2012 Olino K, Edil BH, Meckel KF, Pan X, Thuluvath A, Pardoll DM, Schulick RD, Yoshimura K, Weber WP. Glycolipid antigens for treating hepatic colorectal cancer metastases and their effect on the therapeutic efficacy of live attenuated Listeria monocytogenes. Archives of Surgery (Chicago, Ill. : 1960). 147: 480-2. PMID 22785644 DOI: 10.1001/archsurg.2011.2206  0.334
2012 Pan F, Barbi J, Pardoll DM. Hypoxia-inducible factor 1: A link between metabolism and T cell differentiation and a potential therapeutic target. Oncoimmunology. 1: 510-515. PMID 22754770 DOI: 10.4161/Onci.19457  0.409
2012 Bettini ML, Pan F, Bettini M, Finkelstein D, Rehg JE, Floess S, Bell BD, Ziegler SF, Huehn J, Pardoll DM, Vignali DA. Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency. Immunity. 36: 717-30. PMID 22579476 DOI: 10.1016/J.Immuni.2012.03.020  0.382
2012 Pardoll D, Drake C. Immunotherapy earns its spot in the ranks of cancer therapy Journal of Experimental Medicine. 209: 201-209. PMID 22330682 DOI: 10.1084/Jem.20112275  0.393
2012 Topalian SL, Drake CG, Pardoll DM. Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity. Current Opinion in Immunology. 24: 207-12. PMID 22236695 DOI: 10.1016/J.Coi.2011.12.009  0.418
2012 Woo SR, Turnis ME, Goldberg MV, Bankoti J, Selby M, Nirschl CJ, Bettini ML, Gravano DM, Vogel P, Liu CL, Tangsombatvisit S, Grosso JF, Netto G, Smeltzer MP, Chaux A, ... ... Pardoll DM, et al. Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape. Cancer Research. 72: 917-27. PMID 22186141 DOI: 10.1158/0008-5472.Can-11-1620  0.808
2012 Olino K, Wada S, Edil BH, Pan X, Meckel K, Weber W, Slansky J, Tamada K, Lauer P, Brockstedt D, Pardoll D, Schulick R, Yoshimura K. Tumor-associated antigen expressing Listeria monocytogenes induces effective primary and memory T-cell responses against hepatic colorectal cancer metastases. Annals of Surgical Oncology. 19: S597-607. PMID 21979110 DOI: 10.1245/S10434-011-2037-0  0.304
2012 Bruno TC, Rothwell C, Grosso JF, Getnet D, Yen HR, Durham NM, Netto G, Pardoll DM, Drake CG. Anti-tumor effects of endogenous prostate cancer-specific CD8 T cells in a murine TCR transgenic model. The Prostate. 72: 514-22. PMID 21761425 DOI: 10.1002/Pros.21453  0.495
2011 Topalian SL, Weiner GJ, Pardoll DM. Cancer immunotherapy comes of age. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 4828-36. PMID 22042955 DOI: 10.1200/Jco.2011.38.0899  0.446
2011 Dang EV, Barbi J, Yang HY, Jinasena D, Yu H, Zheng Y, Bordman Z, Fu J, Kim Y, Yen HR, Luo W, Zeller K, Shimoda L, Topalian SL, Semenza GL, ... ... Pardoll DM, et al. Control of TH17/Treg balance by hypoxia-inducible factor 1 Cell. 146: 772-784. PMID 21871655 DOI: 10.1016/J.Cell.2011.07.033  0.405
2011 Davis MB, Vasquez-Dunddel D, Fu J, Albesiano E, Pardoll D, Kim YJ. Intratumoral administration of TLR4 agonist absorbed into a cellular vector improves antitumor responses. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3984-92. PMID 21543518 DOI: 10.1158/1078-0432.Ccr-10-3262  0.481
2011 Lee H, Deng J, Xin H, Liu Y, Pardoll D, Yu H. A requirement of STAT3 DNA binding precludes Th-1 immunostimulatory gene expression by NF-κB in tumors. Cancer Research. 71: 3772-80. PMID 21502401 DOI: 10.1158/0008-5472.Can-10-3304  0.359
2011 Sears CL, Pardoll DM. Perspective: alpha-bugs, their microbial partners, and the link to colon cancer. The Journal of Infectious Diseases. 203: 306-11. PMID 21208921 DOI: 10.1093/Jinfdis/Jiq061  0.301
2010 Wang L, Yi T, Zhang W, Pardoll DM, Yu H. IL-17 enhances tumor development in carcinogen-induced skin cancer. Cancer Research. 70: 10112-20. PMID 21159633 DOI: 10.1158/0008-5472.Can-10-0775  0.376
2010 Le DT, Pardoll DM, Jaffee EM. Cellular vaccine approaches. Cancer Journal (Sudbury, Mass.). 16: 304-10. PMID 20693840 DOI: 10.1097/Ppo.0B013E3181Eb33D7  0.465
2010 Albesiano E, Davis M, See AP, Han JE, Lim M, Pardoll DM, Kim Y. Immunologic consequences of signal transducers and activators of transcription 3 activation in human squamous cell carcinoma. Cancer Research. 70: 6467-76. PMID 20682796 DOI: 10.1158/0008-5472.Can-09-4058  0.424
2010 Nguyen LT, Radhakrishnan S, Ciric B, Tamada K, Shin T, Pardoll DM, Chen L, Rodriguez M, Pease LR. Cross-linking the B7 family molecule B7-DC directly activates immune functions of dendritic cells (The Journal of Experimental Medicine (November 18, 2002) 196, 10 (1393-1398)) Journal of Experimental Medicine. 207: 901. PMID 20368577 DOI: 10.1084/Jem.2002146632610R  0.343
2010 Getnet D, Grosso JF, Goldberg MV, Harris TJ, Yen HR, Bruno TC, Durham NM, Hipkiss EL, Pyle KJ, Wada S, Pan F, Pardoll DM, Drake CG. A role for the transcription factor Helios in human CD4(+)CD25(+) regulatory T cells. Molecular Immunology. 47: 1595-600. PMID 20226531 DOI: 10.1016/J.Molimm.2010.02.001  0.81
2010 Ishiwata K, Watanabe N, Guo M, Tomihara K, Brumlik MJ, Yagita H, Pardoll D, Chen L, Shin T. Costimulator B7-DC attenuates strong Th2 responses induced by Nippostrongylus brasiliensis. Journal of Immunology (Baltimore, Md. : 1950). 184: 2086-94. PMID 20065112 DOI: 10.4049/Jimmunol.0804051  0.355
2009 Brahmer JR, Topalian SL, Powderly J, Wollner I, Picus J, Drake CG, Stankevich E, Korman A, Pardoll D, Lowy I. Phase II experience with MDX-1106 (Ono-4538), an anti-PD-1 monoclonal antibody, in patients with selected refractory or relapsed malignancies. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 3018. PMID 27962055 DOI: 10.1200/Jco.2009.27.15_Suppl.3018  0.331
2009 Yen HR, Harris TJ, Wada S, Grosso JF, Getnet D, Goldberg MV, Liang KL, Bruno TC, Pyle KJ, Chan SL, Anders RA, Trimble CL, Adler AJ, Lin TY, Pardoll DM, et al. Tc17 CD8 T cells: functional plasticity and subset diversity. Journal of Immunology (Baltimore, Md. : 1950). 183: 7161-8. PMID 19917680 DOI: 10.4049/Jimmunol.0900368  0.803
2009 Kortylewski M, Swiderski P, Herrmann A, Wang L, Kowolik C, Kujawski M, Lee H, Scuto A, Liu Y, Yang C, Deng J, Soifer HS, Raubitschek A, Forman S, Rossi JJ, ... Pardoll DM, et al. In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses. Nature Biotechnology. 27: 925-32. PMID 19749770 DOI: 10.1038/Nbt.1564  0.43
2009 Wu S, Rhee KJ, Albesiano E, Rabizadeh S, Wu X, Yen HR, Huso DL, Brancati FL, Wick E, McAllister F, Housseau F, Pardoll DM, Sears CL. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nature Medicine. 15: 1016-22. PMID 19701202 DOI: 10.1038/Nm.2015  0.322
2009 Pan F, Yu H, Dang EV, Barbi J, Pan X, Grosso JF, Jinasena D, Sharma SM, McCadden EM, Getnet D, Drake CG, Liu JO, Ostrowski MC, Pardoll DM. Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells. Science (New York, N.Y.). 325: 1142-6. PMID 19696312 DOI: 10.1126/Science.1176077  0.409
2009 Pletneva M, Fan H, Park JJ, Radojcic V, Jie C, Yu Y, Chan C, Redwood A, Pardoll D, Housseau F. IFN-producing killer dendritic cells are antigen-presenting cells endowed with T-cell cross-priming capacity. Cancer Research. 69: 6607-14. PMID 19679552 DOI: 10.1158/0008-5472.Can-09-0508  0.793
2009 Pardoll D. Metastasis-Promoting Immunity: When T Cells Turn to the Dark Side Cancer Cell. 16: 81-82. PMID 19647215 DOI: 10.1016/J.Ccr.2009.07.007  0.479
2009 Grosso JF, Goldberg MV, Getnet D, Bruno TC, Yen HR, Pyle KJ, Hipkiss E, Vignali DA, Pardoll DM, Drake CG. Functionally distinct LAG-3 and PD-1 subsets on activated and chronically stimulated CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 6659-69. PMID 19454660 DOI: 10.4049/Jimmunol.0804211  0.802
2009 Wada S, Yoshimura K, Hipkiss EL, Harris TJ, Yen HR, Goldberg MV, Grosso JF, Getnet D, Demarzo AM, Netto GJ, Anders R, Pardoll DM, Drake CG. Cyclophosphamide augments antitumor immunity: studies in an autochthonous prostate cancer model. Cancer Research. 69: 4309-18. PMID 19435909 DOI: 10.1158/0008-5472.Can-08-4102  0.822
2009 Lee H, Herrmann A, Deng JH, Kujawski M, Niu G, Li Z, Forman S, Jove R, Pardoll DM, Yu H. Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors. Cancer Cell. 15: 283-93. PMID 19345327 DOI: 10.1016/J.Ccr.2009.02.015  0.305
2009 Getnet D, Maris CH, Hipkiss EL, Grosso JF, Harris TJ, Yen HR, Bruno TC, Wada S, Adler A, Georgantas RW, Jie C, Goldberg MV, Pardoll DM, Drake CG. Tumor recognition and self-recognition induce distinct transcriptional profiles in antigen-specific CD4 T cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 4675-85. PMID 19342643 DOI: 10.4049/Jimmunol.0803400  0.829
2009 Workman CJ, Wang Y, El Kasmi KC, Pardoll DM, Murray PJ, Drake CG, Vignali DA. LAG-3 regulates plasmacytoid dendritic cell homeostasis. Journal of Immunology (Baltimore, Md. : 1950). 182: 1885-91. PMID 19201841 DOI: 10.4049/Jimmunol.0800185  0.461
2009 Kortylewski M, Xin H, Kujawski M, Lee H, Liu Y, Harris T, Drake C, Pardoll D, Yu H. Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment. Cancer Cell. 15: 114-23. PMID 19185846 DOI: 10.1016/J.Ccr.2008.12.018  0.679
2009 Wang T, Jiang Q, Chan C, Gorski KS, McCadden E, Kardian D, Pardoll D, Whartenby KA. Inhibition of activation-induced death of dendritic cells and enhancement of vaccine efficacy via blockade of MINOR. Blood. 113: 2906-13. PMID 19164597 DOI: 10.1182/Blood-2008-08-176354  0.742
2009 Trimble CL, Peng S, Kos F, Gravitt P, Viscidi R, Sugar E, Pardoll D, Wu TC. A phase I trial of a human papillomavirus DNA vaccine for HPV16+ cervical intraepithelial neoplasia 2/3. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 361-7. PMID 19118066 DOI: 10.1158/1078-0432.Ccr-08-1725  0.3
2009 Wolfe JL, Wu S, Wu X, Rhee K, Huso DL, Housseau F, Pardoll DM, Sears CL. M1997 CD4+ Lymphocytes Regulate Colonic Tumor Formation in MIN Mice Colonized with Enterotoxigenic Bacteroides Fragilis (ETBF) Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)62131-4  0.353
2008 Brahmer JR, Topalian S, Wollner I, Powderly JD, Picus J, Drake C, Covino J, Korman A, Pardoll D, Lowy I. Safety and activity of MDX-1106 (ONO-4538), an anti-PD-1 monoclonal antibody, in patients with selected refractory or relapsed malignancies. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 3006. PMID 27947615 DOI: 10.1200/Jco.2008.26.15_Suppl.3006  0.326
2008 Rutebemberwa A, Ray SC, Astemborski J, Levine J, Liu L, Dowd KA, Clute S, Wang C, Korman A, Sette A, Sidney J, Pardoll DM, Cox AL. High-programmed death-1 levels on hepatitis C virus-specific T cells during acute infection are associated with viral persistence and require preservation of cognate antigen during chronic infection. Journal of Immunology (Baltimore, Md. : 1950). 181: 8215-25. PMID 19050238 DOI: 10.4049/Jimmunol.181.12.8215  0.322
2008 Harris TJ, Hipkiss EL, Borzillary S, Wada S, Grosso JF, Yen HR, Getnet D, Bruno TC, Goldberg MV, Pardoll DM, DeWeese TL, Drake CG. Radiotherapy augments the immune response to prostate cancer in a time-dependent manner. The Prostate. 68: 1319-29. PMID 18561247 DOI: 10.1002/Pros.20794  0.817
2008 Matsumoto K, Fukuyama S, Eguchi-Tsuda M, Nakano T, Matsumoto T, Matsumura M, Moriwaki A, Kan-o K, Wada Y, Yagita H, Shin T, Pardoll DM, Patcharee R, Azuma M, Nakanishi Y, et al. B7-DC induced by IL-13 works as a feedback regulator in the effector phase of allergic asthma. Biochemical and Biophysical Research Communications. 365: 170-5. PMID 17981145 DOI: 10.1016/J.Bbrc.2007.10.156  0.332
2008 Wu S, Wu X, Rhee K, Housseau F, Pardoll D, Huso D, Danaher S, Sears C. Enterotoxigenic Bacteroides fragilis colitis is regulated, in part, by CD4+ T lymphocytes: P-103. Inflammatory Bowel Diseases. 14. DOI: 10.1097/00054725-200801001-00136  0.373
2007 Pardoll DM. Building the bionic T cell. Nature Medicine. 13: 1411-3. PMID 18064030 DOI: 10.1038/Nm1207-1411  0.46
2007 Pentcheva-Hoang T, Chen L, Pardoll DM, Allison JP. Programmed death-1 concentration at the immunological synapse is determined by ligand affinity and availability. Proceedings of the National Academy of Sciences of the United States of America. 104: 17765-70. PMID 17968013 DOI: 10.1073/Pnas.0708767104  0.314
2007 Yoshimura K, Laird LS, Chia CY, Meckel KF, Slansky JE, Thompson JM, Jain A, Pardoll DM, Schulick RD. Live attenuated Listeria monocytogenes effectively treats hepatic colorectal cancer metastases and is strongly enhanced by depletion of regulatory T cells. Cancer Research. 67: 10058-66. PMID 17942940 DOI: 10.1158/0008-5472.Can-07-0573  0.475
2007 Grosso JF, Kelleher CC, Harris TJ, Maris CH, Hipkiss EL, De Marzo A, Anders R, Netto G, Getnet D, Bruno TC, Goldberg MV, Pardoll DM, Drake CG. LAG-3 regulates CD8+ T cell accumulation and effector function in murine self- and tumor-tolerance systems. The Journal of Clinical Investigation. 117: 3383-92. PMID 17932562 DOI: 10.1172/Jci31184  0.835
2007 Harris TJ, Grosso JF, Yen HR, Xin H, Kortylewski M, Albesiano E, Hipkiss EL, Getnet D, Goldberg MV, Maris CH, Housseau F, Yu H, Pardoll DM, Drake CG. Cutting edge: An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). 179: 4313-7. PMID 17878325 DOI: 10.4049/Jimmunol.179.7.4313  0.805
2007 Peng S, Trimble C, Wu L, Pardoll D, Roden R, Hung CF, Wu TC. HLA-DQB1*02–Restricted HPV-16 E7 Peptide–Specific CD4+ T-Cell Immune Responses Correlate with Regression of HPV-16–Associated High-Grade Squamous Intraepithelial Lesions Clinical Cancer Research. 13: 2479-2487. PMID 17438108 DOI: 10.1158/1078-0432.Ccr-06-2916  0.326
2007 Goldberg MV, Maris CH, Hipkiss EL, Flies AS, Zhen L, Tuder RM, Grosso JF, Harris TJ, Getnet D, Whartenby KA, Brockstedt DG, Dubensky TW, Chen L, Pardoll DM, Drake CG. Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells. Blood. 110: 186-92. PMID 17392506 DOI: 10.1182/Blood-2006-12-062422  0.811
2007 Lin KY, Lu D, Hung CF, Peng S, Huang L, Jie C, Murillo F, Rowley J, Tsai YC, He L, Kim DJ, Jaffee E, Pardoll D, Wu TC. Ectopic expression of vascular cell adhesion molecule-1 as a new mechanism for tumor immune evasion. Cancer Research. 67: 1832-41. PMID 17308126 DOI: 10.1158/0008-5472.Can-06-3014  0.762
2007 Tsushima F, Yao S, Shin T, Flies A, Flies S, Xu H, Tamada K, Pardoll DM, Chen L. Interaction between B7-H1 and PD-1 determines initiation and reversal of T-cell anergy. Blood. 110: 180-5. PMID 17289811 DOI: 10.1182/Blood-2006-11-060087  0.404
2007 Melero I, Hervas-Stubbs S, Glennie M, Pardoll DM, Chen L. Immunostimulatory monoclonal antibodies for cancer therapy. Nature Reviews. Cancer. 7: 95-106. PMID 17251916 DOI: 10.1038/Nrc2051  0.347
2007 Pan F, Sun L, Kardian DB, Whartenby KA, Pardoll DM, Liu JO. Feedback inhibition of calcineurin and Ras by a dual inhibitory protein Carabin. Nature. 445: 433-6. PMID 17230191 DOI: 10.1038/Nature05476  0.321
2006 Ravi R, Fuchs EJ, Jain A, Pham V, Yoshimura K, Prouser T, Jalla S, Zhou X, Garrett-Mayer E, Kaufmann SH, Schulick RD, Pardoll DM, Bedi A. Resistance of cancers to immunologic cytotoxicity and adoptive immunotherapy via X-linked inhibitor of apoptosis protein expression and coexisting defects in mitochondrial death signaling. Cancer Research. 66: 1730-9. PMID 16452233 DOI: 10.1158/0008-5472.Can-05-3377  0.303
2006 Chan CW, Crafton E, Fan HN, Flook J, Yoshimura K, Skarica M, Brockstedt D, Dubensky TW, Stins MF, Lanier LL, Pardoll DM, Housseau F. Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity. Nature Medicine. 12: 207-13. PMID 16444266 DOI: 10.1038/Nm1352  0.412
2006 Yoshimura K, Jain A, Allen HE, Laird LS, Chia CY, Ravi S, Brockstedt DG, Giedlin MA, Bahjat KS, Leong ML, Slansky JE, Cook DN, Dubensky TW, Pardoll DM, Schulick RD. Selective targeting of antitumor immune responses with engineered live-attenuated Listeria monocytogenes. Cancer Research. 66: 1096-104. PMID 16424046 DOI: 10.1158/0008-5472.Can-05-2307  0.464
2005 Kortylewski M, Kujawski M, Wang T, Wei S, Zhang S, Pilon-Thomas S, Niu G, Kay H, Mulé J, Kerr WG, Jove R, Pardoll D, Yu H. Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity. Nature Medicine. 11: 1314-21. PMID 16288283 DOI: 10.1038/Nm1325  0.454
2005 Laheru DA, Pardoll DM, Jaffee EM. Genes to vaccines for immunotherapy: how the molecular biology revolution has influenced cancer immunology. Molecular Cancer Therapeutics. 4: 1645-52. PMID 16275985 DOI: 10.1158/1535-7163.Mct-05-0151  0.434
2005 Whartenby KA, Calabresi PA, McCadden E, Nguyen B, Kardian D, Wang T, Mosse C, Pardoll DM, Small D. Inhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 16741-6. PMID 16272221 DOI: 10.1073/Pnas.0506088102  0.434
2005 Niu G, Wright KL, Ma Y, Wright GM, Huang M, Irby R, Briggs J, Karras J, Cress WD, Pardoll D, Jove R, Chen J, Yu H. Role of Stat3 in regulating p53 expression and function. Molecular and Cellular Biology. 25: 7432-40. PMID 16107692 DOI: 10.1128/Mcb.25.17.7432-7440.2005  0.324
2005 Cox AL, Mosbruger T, Lauer GM, Pardoll D, Thomas DL, Ray SC. Comprehensive analyses of CD8+ T cell responses during longitudinal study of acute human hepatitis C. Hepatology (Baltimore, Md.). 42: 104-12. PMID 15962289 DOI: 10.1002/Hep.20749  0.327
2005 Kim J, Myers AC, Chen L, Pardoll DM, Truong-Tran QA, Lane AP, McDyer JF, Fortuno L, Schleimer RP. Constitutive and inducible expression of b7 family of ligands by human airway epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 33: 280-9. PMID 15961727 DOI: 10.1165/Rcmb.2004-0129Oc  0.355
2005 Cox AL, Mosbruger T, Mao Q, Liu Z, Wang XH, Yang HC, Sidney J, Sette A, Pardoll D, Thomas DL, Ray SC. Cellular immune selection with hepatitis C virus persistence in humans. The Journal of Experimental Medicine. 201: 1741-52. PMID 15939790 DOI: 10.1084/Jem.20050121  0.383
2005 Shin T, Yoshimura K, Shin T, Crafton EB, Tsuchiya H, Housseau F, Koseki H, Schulick RD, Chen L, Pardoll DM. In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses. The Journal of Experimental Medicine. 201: 1531-41. PMID 15897272 DOI: 10.1084/Jem.20050072  0.449
2005 Burdelya L, Kujawski M, Niu G, Zhong B, Wang T, Zhang S, Kortylewski M, Shain K, Kay H, Djeu J, Dalton W, Pardoll D, Wei S, Yu H. Stat3 activity in melanoma cells affects migration of immune effector cells and nitric oxide-mediated antitumor effects. Journal of Immunology (Baltimore, Md. : 1950). 174: 3925-31. PMID 15778348 DOI: 10.4049/Jimmunol.174.7.3925  0.451
2005 Drake CG, Doody AD, Mihalyo MA, Huang CT, Kelleher E, Ravi S, Hipkiss EL, Flies DB, Kennedy EP, Long M, McGary PW, Coryell L, Nelson WG, Pardoll DM, Adler AJ. Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen. Cancer Cell. 7: 239-49. PMID 15766662 DOI: 10.1016/j.ccr.2005.01.027  0.597
2005 Zhou X, Jun DY, Thomas AM, Huang X, Huang LQ, Mautner J, Mo W, Robbins PF, Pardoll DM, Jaffee EM. Diverse CD8+ T-cell responses to renal cell carcinoma antigens in patients treated with an autologous granulocyte-macrophage colony-stimulating factor gene-transduced renal tumor cell vaccine. Cancer Research. 65: 1079-88. PMID 15705910  0.404
2005 Mautner J, Jaffee EM, Pardoll DM. Tumor-specific CD4+ T cells from a patient with renal cell carcinoma recognize diverse shared antigens. International Journal of Cancer. 115: 752-9. PMID 15704175 DOI: 10.1002/Ijc.20927  0.515
2005 Brockstedt DG, Hampl J, Bahjat K, Lutz E, Leong M, Liu W, Pardoll D, Giedlin M, Jaffee E, Dubensky T. Characterization of Mesothelin-Specific T Cell Responses in Healthy Individuals Journal of Immunotherapy. 28: 631. DOI: 10.1097/01.Cji.0000191007.62728.66  0.397
2005 Aalamian-Mattheis M, Wang J, Jalla S, Hipkiss E, Flies D, Harris T, Drake CG, Pardoll DM, Fuchs EJ. 245: Regression of Prostate Cancer in Animals Treated with Donor Lymphocyte Infusion (DLI) and a Cell Based Tumor Vaccine after Conditioning with a Single Dose of Cyclophosphamide Journal of Urology. 173: 67-67. DOI: 10.1016/S0022-5347(18)34510-5  0.694
2004 Ravi R, Jain AJ, Schulick RD, Pham V, Prouser TS, Allen H, Mayer EG, Yu H, Pardoll DM, Ashkenazi A, Bedi A. Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL. Cancer Research. 64: 9105-14. PMID 15604280 DOI: 10.1158/0008-5472.Can-04-2488  0.337
2004 Huang CT, Workman CJ, Flies D, Pan X, Marson AL, Zhou G, Hipkiss EL, Ravi S, Kowalski J, Levitsky HI, Powell JD, Pardoll DM, Drake CG, Vignali DA. Role of LAG-3 in regulatory T cells. Immunity. 21: 503-13. PMID 15485628 DOI: 10.1016/J.Immuni.2004.08.010  0.778
2004 Yang Y, Huang CT, Huang X, Pardoll DM. Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance. Nature Immunology. 5: 508-15. PMID 15064759 DOI: 10.1038/Ni1059  0.713
2004 Matsumoto K, Inoue H, Nakano T, Tsuda M, Yoshiura Y, Fukuyama S, Tsushima F, Hoshino T, Aizawa H, Akiba H, Pardoll D, Hara N, Yagita H, Azuma M, Nakanishi Y. B7-DC regulates asthmatic response by an IFN-gamma-dependent mechanism. Journal of Immunology (Baltimore, Md. : 1950). 172: 2530-41. PMID 14764726 DOI: 10.4049/Jimmunol.172.4.2530  0.389
2004 Wang T, Niu G, Kortylewski M, Burdelya L, Shain K, Zhang S, Bhattacharya R, Gabrilovich D, Heller R, Coppola D, Dalton W, Jove R, Pardoll D, Yu H. Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells. Nature Medicine. 10: 48-54. PMID 14702634 DOI: 10.1038/Nm976  0.351
2004 Trimble C, Lin CT, Hung CF, Pai S, Juang J, He L, Gillison M, Pardoll D, Wu L, Wu TC. Comparison of the CD8+ T cell responses and antitumor effects generated by DNA vaccine administered through gene gun, biojector, and syringe. Vaccine. 21: 4036-42. PMID 12922140 DOI: 10.1016/S0264-410X(03)00275-5  0.619
2004 Pardoll D, Allison J. Translation of cancer immunotherapies Nature Medicine. 10: 1155-1155. DOI: 10.1038/Nm1104-1155A  0.367
2004 Wang T, Niu G, Kortylewski M, Burdelya L, Shain K, Zhang S, Bhattacharya R, Gabrilovich D, Heller R, Coppola D, Dalton W, Jove R, Pardoll D, Yu H. Erratum: Corrigendum: Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells Nature Medicine. 10: 209-209. DOI: 10.1038/Nm0204-209B  0.334
2003 Gorski KS, Shin T, Crafton E, Otsuji M, Rattis FM, Huang X, Kelleher E, Francisco L, Pardoll D, Tsuchiya H. A set of genes selectively expressed in murine dendritic cells: utility of related cis-acting sequences for lentiviral gene transfer. Molecular Immunology. 40: 35-47. PMID 12909129 DOI: 10.1016/S0161-5890(03)00085-3  0.795
2003 Jain A, Slansky JE, Matey LC, Allen HE, Pardoll DM, Schulick RD. Synergistic effect of a granulocyte-macrophage colony-stimulating factor-transduced tumor vaccine and systemic interleukin-2 in the treatment of murine colorectal cancer hepatic metastases. Annals of Surgical Oncology. 10: 810-20. PMID 12900373 DOI: 10.1245/Aso.2003.10.006  0.378
2003 Youngnak P, Kozono Y, Kozono H, Iwai H, Otsuki N, Jin H, Omura K, Yagita H, Pardoll DM, Chen L, Azuma M. Differential binding properties of B7-H1 and B7-DC to programmed death-1. Biochemical and Biophysical Research Communications. 307: 672-7. PMID 12893276 DOI: 10.1016/S0006-291X(03)01257-9  0.314
2003 Zhou X, Cui Y, Huang X, Yu Z, Thomas AM, Ye Z, Pardoll DM, Jaffee EM, Cheng L. Lentivirus-mediated gene transfer and expression in established human tumor antigen-specific cytotoxic T cells and primary unstimulated T cells. Human Gene Therapy. 14: 1089-105. PMID 12885348 DOI: 10.1089/104303403322124800  0.344
2003 Shin T, Kennedy G, Gorski K, Tsuchiya H, Koseki H, Azuma M, Yagita H, Chen L, Powell J, Pardoll D, Housseau F. Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor. The Journal of Experimental Medicine. 198: 31-8. PMID 12847135 DOI: 10.1084/Jem.20030242  0.755
2003 Cui Y, Kelleher E, Straley E, Fuchs E, Gorski K, Levitsky H, Borrello I, Civin CI, Schoenberger SP, Cheng L, Pardoll DM, Whartenby KA. Immunotherapy of established tumors using bone marrow transplantation with antigen gene--modified hematopoietic stem cells. Nature Medicine. 9: 952-8. PMID 12778137 DOI: 10.1038/Nm882  0.818
2003 Huang CT, Huso DL, Lu Z, Wang T, Zhou G, Kennedy EP, Drake CG, Morgan DJ, Sherman LA, Higgins AD, Pardoll DM, Adler AJ. CD4+ T cells pass through an effector phase during the process of in vivo tolerance induction. Journal of Immunology (Baltimore, Md. : 1950). 170: 3945-53. PMID 12682221 DOI: 10.4049/Jimmunol.170.8.3945  0.684
2003 Pardoll D. Does the Immune System See Tumors as Foreign or Self Annual Review of Immunology. 21: 807-839. PMID 12615893 DOI: 10.1146/Annurev.Immunol.21.120601.141135  0.419
2003 Radhakrishnan S, Nguyen LT, Ciric B, Ure DR, Zhou B, Tamada K, Dong H, Tseng SY, Shin T, Pardoll DM, Chen L, Kyle RA, Rodriguez M, Pease LR. Naturally occurring human IgM antibody that binds B7-DC and potentiates T cell stimulation by dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 1830-8. PMID 12574348  0.804
2003 Luznik L, Slansky JE, Jalla S, Borrello I, Levitsky HI, Pardoll DM, Fuchs EJ. Successful therapy of metastatic cancer using tumor vaccines in mixed allogeneic bone marrow chimeras. Blood. 101: 1645-52. PMID 12406877 DOI: 10.1182/Blood-2002-07-2233  0.667
2002 Pardoll D. T cells take aim at cancer Proceedings of the National Academy of Sciences of the United States of America. 99: 15840-15842. PMID 12461164 DOI: 10.1073/Pnas.262669499  0.506
2002 Pardoll DM. Tumor reactive T cells get a boost. Nature Biotechnology. 20: 1207-8. PMID 12454671 DOI: 10.1038/Nbt1202-1207  0.449
2002 Nguyen LT, Radhakrishnan S, Ciric B, Tamada K, Shin T, Pardoll DM, Chen L, Rodriguez M, Pease LR. Cross-linking the B7 family molecule B7-DC directly activates immune functions of dendritic cells. The Journal of Experimental Medicine. 196: 1393-8. PMID 12438431 DOI: 10.1084/Jem.20021466  0.408
2002 Yamazaki T, Akiba H, Iwai H, Matsuda H, Aoki M, Tanno Y, Shin T, Tsuchiya H, Pardoll DM, Okumura K, Azuma M, Yagita H. Expression of Programmed Death 1 Ligands by Murine T Cells and APC Journal of Immunology. 169: 5538-5545. PMID 12421930 DOI: 10.4049/Jimmunol.169.10.5538  0.432
2002 Whartenby KA, Straley EE, Kim H, Racke F, Tanavde V, Gorski KS, Cheng L, Pardoll DM, Civin CI. Transduction of donor hematopoietic stem-progenitor cells with Fas ligand enhanced short-term engraftment in a murine model of allogeneic bone marrow transplantation. Blood. 100: 3147-54. PMID 12384412 DOI: 10.1182/Blood-2002-01-0118  0.745
2002 Wang XY, Li Y, Manjili MH, Repasky EA, Pardoll DM, Subjeck JR. Hsp110 over-expression increases the immunogenicity of the murine CT26 colon tumor. Cancer Immunology, Immunotherapy : Cii. 51: 311-9. PMID 12111119 DOI: 10.1007/S00262-002-0287-1  0.429
2002 Pardoll DM. Spinning molecular immunology into successful immunotherapy. Nature Reviews Immunology. 2: 227-238. PMID 12001994 DOI: 10.1038/Nri774  0.367
2002 Wilcox RA, Chapoval AI, Gorski KS, Otsuji M, Shin T, Flies DB, Tamada K, Mittler RS, Tsuchiya H, Pardoll DM, Chen L. Cutting edge: Expression of functional CD137 receptor by dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 168: 4262-7. PMID 11970964 DOI: 10.4049/Jimmunol.168.9.4262  0.76
2002 Housseau F, Langer DA, Oberholtzer SD, Moorthy A, Levitsky HI, Pardoll DM, Topalian SL. Tumor-specific CD8+ T lymphocytes derived from the peripheral blood of prostate cancer patients by in vitro stimulation with autologous tumor cell lines. International Journal of Cancer. Journal International Du Cancer. 98: 57-62. PMID 11857386 DOI: 10.1002/Ijc.10154  0.695
2001 Pardoll DM. Immunology. Stress, NK receptors, and immune surveillance. Science. 294: 534-536. PMID 11567108 DOI: 10.1126/Science.1066284  0.428
2001 O'Herrin SM, Slansky JE, Tang Q, Markiewicz MA, Gajewski TF, Pardoll DM, Schneck JP, Bluestone JA. Antigen-specific blockade of T cells in vivo using dimeric MHC peptide Journal of Immunology. 167: 2555-2560. PMID 11509595 DOI: 10.4049/Jimmunol.167.5.2555  0.442
2001 Golgher D, Korangy F, Gao B, Gorski K, Jaffee E, Edidin M, Pardoll DM, Elliott T. An immunodominant MHC class II-restricted tumor antigen is conformation dependent and binds to the endoplasmic reticulum chaperone, calreticulin Journal of Immunology. 167: 147-155. PMID 11418643 DOI: 10.4049/Jimmunol.167.1.147  0.758
2001 Hamad ARA, Srikrishnan A, Mirmonsef P, Broeren CPM, June CH, Pardoll D, Schneck JP. Lack of coreceptor allows survival of chronically stimulated double-negative α/β T cells: Implications for autoimmunity Journal of Experimental Medicine. 193: 1113-1121. PMID 11369783 DOI: 10.1084/Jem.193.10.1113  0.441
2001 Tseng SY, Otsuji M, Gorski K, Huang X, Slansky JE, Pai SI, Shalabi A, Shin T, Pardoll DM, Tsuchiya H. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. The Journal of Experimental Medicine. 193: 839-46. PMID 11283156 DOI: 10.1084/Jem.193.7.839  0.813
2000 Slansky JE, Rattis FM, Boyd LF, Fahmy T, Jaffee EM, Schneck JP, Margulies DH, Pardoll DM. Enhanced antigen-specific antitumor immunity with altered peptide ligands that stabilize the MHC-peptide-TCR complex Immunity. 13: 529-538. PMID 11070171 DOI: 10.1016/S1074-7613(00)00052-2  0.449
2000 Chen CH, Suh KW, Ji H, Choti MA, Pardoll DM, Wu TC. Antigen-specific immunotherapy for human papillomavirus 16 E7-expressing tumors grown in the liver Journal of Hepatology. 33: 91-98. PMID 10905591 DOI: 10.1016/S0168-8278(00)80164-6  0.416
2000 Wang TL, Ling M, Shih IM, Pham T, Pai SI, Lu Z, Kurman RJ, Pardoll DM, Wu TC. Intramuscular administration of E7-transfected dendritic cells generates the most potent E7-specific anti-tumor immunity. Gene Therapy. 7: 726-33. PMID 10822298 DOI: 10.1038/sj.gt.3301160  0.824
2000 Pardoll DM. Therapeutic Vaccination for Cancer Clinical Immunology. 95. PMID 10729237 DOI: 10.1006/Clim.1999.4819  0.315
2000 DiMeco F, Rhines LD, Hanes J, Tyler BM, Brat D, Torchiana E, Guarnieri M, Colombo MP, Pardoll DM, Finocchiaro G, Brem H, Olivi A. Paracrine delivery of IL-12 against intracranial 9L gliosarcoma in rats. Journal of Neurosurgery. 92: 419-27. PMID 10701528 DOI: 10.3171/Jns.2000.92.3.0419  0.307
2000 Lu Z, Yuan L, Zhou X, Sotomayor E, Levitsky HI, Pardoll DM. CD40-independent pathways of T cell help for priming of CD8(+) cytotoxic T lymphocytes. The Journal of Experimental Medicine. 191: 541-50. PMID 10662799 DOI: 10.1084/Jem.191.3.541  0.808
2000 Adler AJ, Huang CT, Yochum GS, Marsh DW, Pardoll DM. In vivo CD4+ T cell tolerance induction versus priming is independent of the rate and number of cell divisions. Journal of Immunology (Baltimore, Md. : 1950). 164: 649-55. PMID 10623806 DOI: 10.4049/Jimmunol.164.2.649  0.688
1999 Suh KW, Piantadosi S, Yazdi HA, Pardoll DM, Brem H, Choti MA. Treatment of liver metastases from colon carcinoma with autologous tumor vaccine expressing granulocyte-macrophage colony-stimulating factor Journal of Surgical Oncology. 72: 218-224. PMID 10589037 DOI: 10.1002/(Sici)1096-9098(199912)72:4<218::Aid-Jso7>3.0.Co;2-N  0.403
1999 Ji H, Wang TL, Chen CH, Pai SI, Hung CF, Lin KY, Kurman RJ, Pardoll DM, Wu TC. Targeting human papillomavirus type 16 E7 to the endosomal/lysosomal compartment enhances the antitumor immunity of DNA vaccines against murine human papillomavirus type 16 E7-expressing tumors. Human Gene Therapy. 10: 2727-40. PMID 10584920 DOI: 10.1089/10430349950016474  0.786
1999 Pardoll DM. Inducing autoimmune disease to treat cancer Proceedings of the National Academy of Sciences of the United States of America. 96: 5340-5342. PMID 10318881 DOI: 10.1073/Pnas.96.10.5340  0.462
1998 Hamad AR, O'Herrin SM, Lebowitz MS, Srikrishnan A, Bieler J, Schneck J, Pardoll D. Potent T cell activation with dimeric peptide-major histocompatibility complex class II ligand: the role of CD4 coreceptor. The Journal of Experimental Medicine. 188: 1633-40. PMID 9802975 DOI: 10.1084/Jem.188.9.1633  0.429
1998 Pardoll DM, Topalian SL. The role of CD4+ T cell responses in antitumor immunity Current Opinion in Immunology. 10: 588-594. PMID 9794842 DOI: 10.1016/S0952-7915(98)80228-8  0.532
1998 Jaffee EM, Abrams R, Cameron J, Donehower R, Duerr M, Gossett J, Greten TF, Grochow L, Hruban R, Kern S, Lillemoe KD, O'Reilly S, Pardoll D, Pitt HA, Sauter P, et al. A Phase I Clinical Trial of Lethally Irradiated Allogeneic Pancreatic Tumor Cells Transfected with the GM-CSF Gene for the Treatment of Pancreatic Adenocarcinoma. The Johns Hopkins Oncology Center, Baltimore, Maryland Human Gene Therapy. 9: 1951-1971. PMID 9741433 DOI: 10.1089/Hum.1998.9.13-1951  0.317
1998 Ji H, Chang EY, Lin KY, Kurman RJ, Pardoll DM, Wu TC. Antigen-specific immunotherapy for murine lung metastatic tumors expressing human papillomavirus type 16 E7 oncoprotein. International Journal of Cancer. 78: 41-5. PMID 9724092 DOI: 10.1002/(SICI)1097-0215(19980925)78:1<41::AID-IJC8>3.0.CO;2-X  0.731
1998 Greten TF, Slansky JE, Kubota R, Soldan SS, Jaffee EM, Leist TP, Pardoll DM, Jacobson S, Schneck JP. Direct visualization of antigen-specific T cells: HTLV-1 TAX11-19- specific CD8+ T cells are activated in peripheral blood and accumulate in cerebrospinal fluid from HAM/TSP patients Proceedings of the National Academy of Sciences of the United States of America. 95: 7568-7573. PMID 9636190 DOI: 10.1073/Pnas.95.13.7568  0.423
1998 Adler AJ, Marsh DW, Yochum GS, Guzzo JL, Nigam A, Nelson WG, Pardoll DM. CD4+ T cell tolerance to parenchymal self-antigens requires presentation by bone marrow-derived antigen-presenting cells Journal of Experimental Medicine. 187: 1555-1564. PMID 9584134 DOI: 10.1084/Jem.187.10.1555  0.466
1998 Thomas MC, Greten TF, Pardoll DM, Jaffee EM. Enhanced tumor protection by granulocyte-macrophage colony-stimulating factor expression at the site of an allogeneic vaccine. Human Gene Therapy. 9: 835-43. PMID 9581906 DOI: 10.1089/Hum.1998.9.6-835  0.463
1998 Nigam A, Yacavone RF, Zahurak ML, Johns CM, Pardoll DM, Piantadosi S, Levitsky HI, Nelson WG. Immunomodulatory properties of antineoplastic drugs administered in conjunction with GM-CSF-secreting cancer cell vaccines. International Journal of Oncology. 12: 161-70. PMID 9454900 DOI: 10.3892/Ijo.12.1.161  0.658
1998 Staveley-O'Carroll K, Sotomayor E, Montgomery J, Borrello I, Hwang L, Fein S, Pardoll D, Levitsky H. Induction of antigen-specific T cell anergy: An early event in the course of tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 95: 1178-83. PMID 9448305 DOI: 10.1073/Pnas.95.3.1178  0.729
1997 Jaffee EM, Pardoll DM. Considerations for the clinical development of cytokine gene-transduced tumor cell vaccines. Methods (San Diego, Calif.). 12: 143-53. PMID 9184378 DOI: 10.1006/Meth.1997.0463  0.406
1997 Pardoll D. Maturation of cancer vaccines. A meeting report on 'Cancer Vaccines 1996,' sponsored by the Cancer Research Institute, held October 7-9, 1996. Biochimica Et Biophysica Acta. 1332. PMID 9141467 DOI: 10.1016/S0304-419X(97)00005-X  0.308
1996 Huang AY, Gulden PH, Woods AS, Thomas MC, Tong CD, Wang W, Engelhard VH, Pasternack G, Cotter R, Hunt D, Pardoll DM, Jaffee EM. The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product. Proceedings of the National Academy of Sciences of the United States of America. 93: 9730-5. PMID 8790399 DOI: 10.1073/Pnas.93.18.9730  0.8
1996 Fort MM, Pardoll DM. Can bone marrow-derived thymic stromal cells mediate the positive selection of class I-restricted T cells? Cellular Immunology. 171: 74-9. PMID 8660840 DOI: 10.1006/Cimm.1996.0175  0.43
1996 Huang AY, Bruce AT, Pardoll DM, Levitsky HI. Does B7-1 expression confer antigen-presenting cell capacity to tumors in vivo? The Journal of Experimental Medicine. 183: 769-76. PMID 8642281 DOI: 10.1084/Jem.183.3.769  0.702
1996 Huang AY, Bruce AT, Pardoll DM, Levitsky HI. In vivo cross-priming of MHC class I-restricted antigens requires the TAP transporter. Immunity. 4: 349-55. PMID 8612129 DOI: 10.1016/S1074-7613(00)80248-4  0.632
1996 Lin KY, Guarnieri FG, Staveley-O'Carroll KF, Levitsky HI, August JT, Pardoll DM, Wu TC. Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen. Cancer Research. 56: 21-6. PMID 8548765  0.817
1995 Wu TC, Guarnieri FG, Staveley-O'Carroll KF, Viscidi RP, Levitsky HI, Hedrick L, Cho KR, August JT, Pardoll DM. Engineering an intracellular pathway for major histocompatibility complex class II presentation of antigens. Proceedings of the National Academy of Sciences of the United States of America. 92: 11671-5. PMID 8524826 DOI: 10.1073/Pnas.92.25.11671  0.768
1995 Pardoll DM, Beckerleg AM. Exposing the immunology of naked DNA vaccines. Immunity. 3: 165-9. PMID 7648389 DOI: 10.1016/1074-7613(95)90085-3  0.748
1995 Pardoll DM. Paracrine Cytokine Adjuvants in Cancer Immunotherapy Annual Review of Immunology. 13: 399-415. PMID 7612229 DOI: 10.1146/Annurev.Iy.13.040195.002151  0.48
1995 Pan ZK, Ikonomidis G, Lazenby A, Pardoll D, Paterson Y. A recombinant Listeria monocytogenes vaccine expressing a model tumour antigen protects mice against lethal tumour cell challenge and causes regression of established tumours Nature Medicine. 1: 471-477. PMID 7585097 DOI: 10.1038/Nm0595-471  0.417
1994 Golumbek P, Levitsky H, Jaffee L, Pardoll DM. The antitumor immune response as a problem of self-nonself discrimination: implications for immunotherapy. Immunologic Research. 12: 183-92. PMID 8254226 DOI: 10.1007/Bf02918303  0.712
1994 Levitsky HI, Lazenby A, Hayashi RJ, Pardoll DM. In vivo priming of two distinct antitumor effector populations: the role of MHC class I expression. The Journal of Experimental Medicine. 179: 1215-24. PMID 7908321 DOI: 10.1084/Jem.179.4.1215  0.72
1993 Pardoll DM. New strategies for enhancing the immunogenicity of tumors. Current Opinion in Immunology. 5: 719-725. PMID 7694593 DOI: 10.1016/0952-7915(93)90127-E  0.466
1993 Pardoll DM. Genetically Engineered Tumor Vaccines Annals of the New York Academy of Sciences. 690: 301-310. PMID 7690216 DOI: 10.1111/J.1749-6632.1993.Tb44018.X  0.315
1993 Golumbek PT, Hamzeh FM, Jaffee EM, Levitsky H, Lietman PS, Pardoll DM. Herpes simplex-1 virus thymidine kinase gene is unable to completely eliminate live, nonimmunogenic tumor cell vaccines. Journal of Immunotherapy : Official Journal of the Society For Biological Therapy. 12: 224-30. PMID 1335754 DOI: 10.1097/00002371-199211000-00002  0.689
1992 Carrera AC, Baker C, Roberts TM, Pardoll DM. Tyrosine kinase triggering in thymocytes undergoing positive selection. European Journal of Immunology. 22: 2289-94. PMID 1516620 DOI: 10.1002/Eji.1830220917  0.376
1992 Pardoll D. Immunotherapy with cytokine gene-transduced tumor cells: the next wave in gene therapy for cancer. Current Opinion in Oncology. 4: 1124-1129. PMID 1457527 DOI: 10.1097/00001622-199212000-00018  0.413
1992 Pardoll D. New strategies for active immunotherapy with genetically engineered tumor cells. Current Opinion in Immunology. 4: 619-623. PMID 1418729 DOI: 10.1016/0952-7915(92)90037-F  0.452
1992 Heuze F, Pardoll D, Diez E, Ezine S, Jotereau F. Molecular analysis of a pro-T cell clone transformed by Abelson-murine leukemia virus, displaying progressive gamma delta T cell receptor gene rearrangement and surface expression. European Journal of Immunology. 22: 2077-84. PMID 1322302 DOI: 10.1002/Eji.1830220818  0.414
1992 Pardoll D, Golumbek P, Jaffee L, Levitsky H, Dranoff G, Mulligan R. MOLECULAR ENGINEERING OF THE ANTITUMOR IMMUNE RESPONSE Journal of Immunotherapy. 11: 137. DOI: 10.1097/00002371-199202000-00044  0.607
1990 Saito T, Pardoll DM, Fowlkes BJ, Ohno H. A murine thymocyte clone expressing gamma delta T cell receptor mediates natural killer-like cytolytic function and TH1-like lymphokine production. Cellular Immunology. 131: 284-301. PMID 2146987 DOI: 10.1016/0008-8749(90)90255-P  0.441
1989 Janis EM, Kaufmann SH, Schwartz RH, Pardoll DM. Activation of gamma delta T cells in the primary immune response to Mycobacterium tuberculosis. Science (New York, N.Y.). 244: 713-6. PMID 2524098 DOI: 10.1126/Science.2524098  0.435
1989 Fowlkes BJ, Pardoll DM. Molecular and cellular events of T cell development Advances in Immunology. 44: 207-264. PMID 2493727 DOI: 10.1016/S0065-2776(08)60643-4  0.339
1988 Koning F, Kruisbeek AM, Maloy WL, Marusic-Galesic S, Pardoll DM, Shevach EM, Stingl G, Valas R, Yokoyama WM, Coligan JE. T cell receptor gamma/delta chain diversity. The Journal of Experimental Medicine. 167: 676-81. PMID 3258012 DOI: 10.1084/Jem.167.2.676  0.501
1987 Bluestone JA, Pardoll D, Sharrow SO, Fowlkes BJ. Characterization of murine thymocytes with CDS-associated T-cell receptor structures Nature. 326: 82-84. PMID 3102972 DOI: 10.1038/326082A0  0.431
1986 Lew AM, Pardoll DM, Maloy WL, Fowlkes BJ, Kruisbeek A, Cheng SF, Germain RN, Bluestone JA, Schwartz RH, Coligan JE. Characterization of T cell receptor gamma chain expression in a subset of murine thymocytes Science. 234: 1401-1405. PMID 3787252 DOI: 10.1126/Science.3787252  0.388
1980 Vogelstein B, Pardoll DM, Coffey DS. Supercoiled loops and eukaryotic DNA replication Cell. 22: 79-85. PMID 7428042 DOI: 10.1016/0092-8674(80)90156-7  0.413
1980 Pardoll DM, Vogelstein B, Coffey DS. A fixed site of DNA replication in eucaryotic cells Cell. 19: 527-536. PMID 7357619 DOI: 10.1016/0092-8674(80)90527-9  0.422
1979 Shaper JH, Pardoll DM, Kaufmann SH, Barrack ER, Vogelstein B, Coffey DS. The relationship of the nuclear matrix to cellular structure and function Advances in Enzyme Regulation. 17: 213-220,IN3-IN6,221-. DOI: 10.1016/0065-2571(79)90015-3  0.389
Low-probability matches (unlikely to be authored by this person)
2018 Maxwell R, Luksik AS, Garzon-Muvdi T, Hung AL, Kim ES, Wu A, Xia Y, Belcaid Z, Gorelick N, Choi J, Theodros D, Jackson CM, Mathios D, Ye X, Tran PT, ... ... Pardoll DM, et al. Contrasting impact of corticosteroids on anti-PD-1 immunotherapy efficacy for tumor histologies located within or outside the central nervous system. Oncoimmunology. 7: e1500108. PMID 30524891 DOI: 10.1080/2162402X.2018.1500108  0.298
2018 Antonarakis ES, Shaukat F, Isaacsson Velho P, Kaur H, Shenderov E, Pardoll DM, Lotan TL. Clinical Features and Therapeutic Outcomes in Men with Advanced Prostate Cancer and DNA Mismatch Repair Gene Mutations. European Urology. PMID 30337059 DOI: 10.1016/J.Eururo.2018.10.009  0.298
2007 Hege KM, Jooss K, Pardoll D. GM-CSF gene-modifed cancer cell immunotherapies: of mice and men. International Reviews of Immunology. 25: 321-52. PMID 17169779 DOI: 10.1080/08830180600992498  0.298
2009 Wu S, Rhee K, Rabizadeh S, Albesiano E, Yen H, Wu X, Huso DL, Housseau F, Pardoll DM, Sears CL. M1999 Enterotoxigenic Bacteroides Fragilis Colonic Infection Promotes Colon Tumorigenesis in APCMIN/+ Mice via Activation of TH17 T Cell Responses Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)62133-8  0.297
2001 Hanes J, Sills A, Zhao Z, Suh KW, Tyler B, DiMeco F, Brat DJ, Choti MA, Leong KW, Pardoll DM, Brem H. Controlled local delivery of interleukin-2 by biodegradable polymers protects animals from experimental brain tumors and liver tumors. Pharmaceutical Research. 18: 899-906. PMID 11496947 DOI: 10.1023/A:1010963307097  0.297
2022 Harbison RA, Pandey R, Considine M, Leone RD, Murray-Stewart T, Erbe R, Mandal R, Burns M, Casero RA, Seiwert T, Fakhry C, Pardoll D, Fertig E, Powell JD. Interrogation of T Cell-Enriched Tumors Reveals Prognostic and Immunotherapeutic Implications of Polyamine Metabolism. Cancer Research Communications. 2: 639-652. PMID 36052016 DOI: 10.1158/2767-9764.crc-22-0061  0.296
2022 Sidhom JW, Oliveira G, Ross-MacDonald P, Wind-Rotolo M, Wu CJ, Pardoll DM, Baras AS. Deep learning reveals predictive sequence concepts within immune repertoires to immunotherapy. Science Advances. 8: eabq5089. PMID 36112691 DOI: 10.1126/sciadv.abq5089  0.296
2023 Jackson C, Cherry C, Bom S, Dykema AG, Thompson E, Zheng M, Ji Z, Hou W, Li R, Zhang H, Choi J, Rodriguez F, Weingart J, Yegnasubramanian S, Lim M, ... ... Pardoll D, et al. Distinct Myeloid Derived Suppressor Cell Populations Promote Tumor Aggression in Glioblastoma. Biorxiv : the Preprint Server For Biology. PMID 37034584 DOI: 10.1101/2023.03.26.534192  0.296
2008 Jordan KR, McMahan RH, Oh JZ, Pipeling MR, Pardoll DM, Kedl RM, Kappler JW, Slansky JE. Baculovirus-infected insect cells expressing peptide-MHC complexes elicit protective antitumor immunity. Journal of Immunology (Baltimore, Md. : 1950). 180: 188-97. PMID 18097019 DOI: 10.4049/Jimmunol.180.1.188  0.295
2002 Drake CG, Pardoll DM. Tumor immunology--towards a paradigm of reciprocal research. Seminars in Cancer Biology. 12: 73-80. PMID 11926415 DOI: 10.1006/scbi.2001.0403  0.295
2019 Mathios D, Hwang T, Xia Y, Phallen J, Rui Y, See AP, Maxwell R, Belcaid Z, Casaos J, Burger PC, McDonald KL, Gallia GL, Cope L, Kai M, Brem H, ... Pardoll DM, et al. Genome-wide investigation of intragenic DNA methylation identifies ZMIZ1 gene as a prognostic marker in glioblastoma and multiple cancer types. International Journal of Cancer. PMID 31373686 DOI: 10.1002/Ijc.32587  0.294
2024 Yu H, Nishio H, Barbi J, Mitchell-Flack M, Vignali PDA, Zheng Y, Lebid A, Chang KY, Fu J, Higgins M, Huang CT, Zhang X, Li Z, Blosser L, Tam A, ... ... Pardoll DM, et al. Neurotrophic factor Neuritin modulates T cell electrical and metabolic state for the balance of tolerance and immunity. Biorxiv : the Preprint Server For Biology. PMID 38352414 DOI: 10.1101/2024.01.31.578284  0.294
2012 Tomihara K, Shin T, Hurez VJ, Yagita H, Pardoll DM, Zhang B, Curiel TJ, Shin T. Aging-associated B7-DC+ B cells enhance anti-tumor immunity via Th1 and Th17 induction. Aging Cell. 11: 128-38. PMID 22044484 DOI: 10.1111/J.1474-9726.2011.00764.X  0.292
2008 Wölfl M, Rutebemberwa A, Mosbruger T, Mao Q, Li HM, Netski D, Ray SC, Pardoll D, Sidney J, Sette A, Allen T, Kuntzen T, Kavanagh DG, Kuball J, Greenberg PD, et al. Hepatitis C virus immune escape via exploitation of a hole in the T cell repertoire. Journal of Immunology (Baltimore, Md. : 1950). 181: 6435-46. PMID 18941234 DOI: 10.4049/Jimmunol.181.9.6435  0.29
2023 Topalian SL, Sznol M, McDermott DF, Kluger HM, Carvajal RD, Sharfman WH, Brahmer JR, Lawrence DP, Atkins MB, Powderly JD, Leming PD, Lipson EJ, Puzanov I, Smith DC, Taube JM, ... ... Pardoll DM, et al. Survival, Durable Tumor Remission, and Long-Term Safety in Patients With Advanced Melanoma Receiving Nivolumab. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 41: 943-954. PMID 36750016 DOI: 10.1200/JCO.22.02272  0.29
2014 Topalian SL, Sznol M, McDermott DF, Kluger HM, Carvajal RD, Sharfman WH, Brahmer JR, Lawrence DP, Atkins MB, Powderly JD, Leming PD, Lipson EJ, Puzanov I, Smith DC, Taube JM, ... ... Pardoll DM, et al. Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 1020-30. PMID 24590637 DOI: 10.1200/JCO.2013.53.0105  0.29
2015 Rodi? N, Anders RA, Eshleman JR, Lin MT, Xu H, Kim JH, Beierl K, Chen S, Luber BS, Wang H, Topalian SL, Pardoll DM, Taube JM. PD-L1 expression in melanocytic lesions does not correlate with the BRAF V600E mutation. Cancer Immunology Research. 3: 110-5. PMID 25370533 DOI: 10.1158/2326-6066.Cir-14-0145  0.289
2002 Cui Y, Golob J, Kelleher E, Ye Z, Pardoll D, Cheng L. Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells. Blood. 99: 399-408. PMID 11781219 DOI: 10.1182/Blood.V99.2.399  0.288
2023 Topalian SL, Forde PM, Emens LA, Yarchoan M, Smith KN, Pardoll DM. Neoadjuvant immune checkpoint blockade: A window of opportunity to advance cancer immunotherapy. Cancer Cell. PMID 37595586 DOI: 10.1016/j.ccell.2023.07.011  0.287
2015 Jackson CM, Kochel CM, Nirschl CJ, Durham NM, Ruzevick J, Alme A, Francica BJ, Elias J, Daniels A, Dubensky TW, Lauer P, Brockstedt D, Baxi EG, Calabresi PA, Taube JM, ... ... Pardoll DM, et al. Systemic Tolerance Mediated by Melanoma Brain Tumors is Reversible by Radiotherapy and Vaccination. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26490306 DOI: 10.1158/1078-0432.Ccr-15-1516  0.285
2003 Lesniak MS, Tyler BM, Pardoll DM, Brem H. Gene therapy for experimental brain tumors using a xenogenic cell line engineered to secrete hIL-2. Journal of Neuro-Oncology. 64: 155-60. PMID 12952296 DOI: 10.1007/BF02700030  0.285
2016 Topalian SL, Taube JM, Anders RA, Pardoll DM. Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy. Nature Reviews. Cancer. PMID 27079802 DOI: 10.1038/nrc.2016.36  0.284
1998 Hanes J, Tyler BM, Suh KW, DiMeco F, Brat D, Choti M, Pardoll D, Brem H. Synthetic Cytokine Delivery Systems for Cancer Immunotherapy Neurosurgery. 43: 715-716. DOI: 10.1097/00006123-199809000-00361  0.284
2015 Beachley VZ, Wolf MT, Sadtler K, Manda SS, Jacobs H, Blatchley MR, Bader JS, Pandey A, Pardoll D, Elisseeff JH. Tissue matrix arrays for high-throughput screening and systems analysis of cell function. Nature Methods. PMID 26480475 DOI: 10.1038/Nmeth.3619  0.282
2012 Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nature Reviews. Cancer. 12: 252-64. PMID 22437870 DOI: 10.1038/nrc3239  0.282
2016 Kim JE, Patel MA, Mangraviti A, Kim ES, Theodros D, Velarde E, Liu A, Sankey E, Tam A, Xu H, Mathios D, Jackson CM, Harris-Bookman S, Garzon-Muvdi T, Sheu M, ... ... Pardoll DM, et al. Combination therapy with anti-PD-1, anti-TIM-3, and focal radiation results in regression of murine gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27358487 DOI: 10.1158/1078-0432.Ccr-15-1535  0.282
2016 Patel MA, Kim JE, Theodros D, Tam A, Velarde E, Kochel CM, Francica B, Nirschl TR, Ghasemzadeh A, Mathios D, Harris-Bookman S, Jackson CC, Jackson C, Ye X, Tran PT, ... ... Pardoll DM, et al. Erratum to: Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma. Journal For Immunotherapy of Cancer. 4: 74. PMID 27822377 DOI: 10.1186/S40425-016-0181-6  0.281
2011 Zeng J, See AP, Phallen J, Belcaid Z, Durham N, Ford E, Tran PT, Pardoll D, Drake CG, Lim M. Combining Anti-PD-1 (B7-H1) Immunotherapy with Stereotactic Radiosurgery in a Mouse Orthotopic Glioblastoma Model International Journal of Radiation Oncology Biology Physics. 81. DOI: 10.1016/J.Ijrobp.2011.06.167  0.281
2017 Smith K, Anagnostou V, Forde P, Brahmer J, Velculescu V, Pardoll D. OA20.02 Neoantigen Targeting in NSCLC Patients with Complete Response to Anti-PD-1 Immunotherapy Journal of Thoracic Oncology. 12. DOI: 10.1016/J.Jtho.2016.11.344  0.281
2003 Nimmerjahn F, Milosevic S, Behrends U, Jaffee EM, Pardoll DM, Bornkamm GW, Mautner J. Major histocompatibility complex class II-restricted presentation of a cytosolic antigen by autophagy. European Journal of Immunology. 33: 1250-9. PMID 12731050 DOI: 10.1002/Eji.200323730  0.28
2016 Sadtler K, Singh A, Wolf MT, Wang X, Pardoll DM, Elisseeff JH. Design, clinical translation and immunological response of biomaterials in regenerative medicine Nature Reviews Materials. 1. DOI: 10.1038/Natrevmats.2016.40  0.279
2008 Trimble C, Thoburn C, Kos F, Peng S, Viscidi R, Gravitt P, Roden R, Wu T, Pardoll D, Sugar E, Jungbluth A. Su.98. Mechanisms of Immune Privilege in High Grade Cervical Dysplasia Clinical Immunology. 127: S156. DOI: 10.1016/J.Clim.2008.03.449  0.279
2018 Chung L, Orberg ET, Geis AL, Chan JL, Fu K, DeStefano Shields CE, Dejea CM, Fathi P, Chen J, Finard BB, Tam AJ, McAllister F, Fan H, Wu X, Ganguly S, ... ... Pardoll DM, et al. Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells. Cell Host & Microbe. 23: 421. PMID 29544099 DOI: 10.1016/J.Chom.2018.02.004  0.278
2002 Clatterbuck RE, Oshiro EM, Hoffman PA, Dietsch GN, Pardoll DM, Tamargo RJ. Inhibition of vasospasm with lymphocyte function-associated antigen-1 monoclonal antibody in a femoral artery model in rats. Journal of Neurosurgery. 97: 676-82. PMID 12296653 DOI: 10.3171/Jns.2002.97.3.0676  0.278
2019 Sloan L, Sen R, Doucet M, Blosser L, Shpitser I, Cheng Z, Katulis L, Wemmer J, Jackson C, Hu C, McNutt T, Grossman S, Holdhoff M, Lim M, Redmond K, ... ... Pardoll D, et al. The Immunodynamics of Myeloid-Derived Suppressor Cell and Monocyte Populations in the Peripheral Blood in Patients with Newly Diagnosed Glioblastoma Undergoing Adjuvant Temozolomide and Radiation Therapy International Journal of Radiation Oncology*Biology*Physics. 105: E650-E651. DOI: 10.1016/J.Ijrobp.2019.06.1029  0.277
2018 Sears CL, Pardoll DM. The intestinal microbiome influences checkpoint blockade. Nature Medicine. 24: 254-255. PMID 29509750 DOI: 10.1038/Nm.4511  0.276
1987 Pardoll DM, Fowlkes BJ, Lechler RI, Germain RN, Schwartz RH. Early genetic events in T cell development analyzed by in situ hybridization Journal of Experimental Medicine. 165: 1624-1638. PMID 2884272 DOI: 10.1084/Jem.165.6.1624  0.276
2007 Yu H, Kortylewski M, Pardoll D. Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nature Reviews. Immunology. 7: 41-51. PMID 17186030 DOI: 10.1038/nri1995  0.274
2011 Humphrey RW, Brockway-Lunardi LM, Bonk DT, Dohoney KM, Doroshow JH, Meech SJ, Ratain MJ, Topalian SL, Pardoll DM. Opportunities and challenges in the development of experimental drug combinations for cancer. Journal of the National Cancer Institute. 103: 1222-6. PMID 21765011 DOI: 10.1093/Jnci/Djr246  0.273
2003 Couch M, Saunders JK, O'Malley BW, Pardoll D, Jaffee E. Genetically engineered tumor cell vaccine in a head and neck cancer model. The Laryngoscope. 113: 552-6. PMID 12616213 DOI: 10.1097/00005537-200303000-00029  0.272
2021 Cheung LS, Chen L, Oke TF, Schaffer TB, Boudadi K, Ngo JT, Gross JM, Kemberling H, Diaz LA, Lipson E, Sidhom JW, Taube J, Anders R, Pardoll DM, Le DT, et al. Anti-PD-1 elicits regression of undifferentiated pleomorphic sarcomas with UV-mutation signatures. Journal For Immunotherapy of Cancer. 9. PMID 34103354 DOI: 10.1136/jitc-2021-002345  0.27
2021 Kumar R, Mendonca J, Owoyemi O, Boyapati K, Thomas N, Kanacharoen S, Coffey M, Topiwala D, Gomes C, Ozbek B, Jones T, Rosen M, Dong L, Wiens S, Brennen WN, ... ... Pardoll DM, et al. Supraphysiological testosterone induces ferroptosis and activates immune pathways through nucleophagy in prostate cancer. Cancer Research. PMID 34645612 DOI: 10.1158/0008-5472.CAN-20-3607  0.27
2020 Peloza KE, Gills JJ, Shaikh FY, White JR, Glass S, Lansiquot C, Stevens C, Assan W, Sharfman WH, Le DT, Naidoo J, Lipson EJ, Pardoll DM, Sears CL. Abstract B13: Development of a low-cost method for collecting fecal samples in clinical trials Cancer Research. 80. DOI: 10.1158/1538-7445.Mvc2020-B13  0.269
2014 Chattergoon MA, Latanich R, Quinn J, Winter ME, Buckheit RW, Blankson JN, Pardoll D, Cox AL. HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon. Plos Pathogens. 10: e1004082. PMID 24788318 DOI: 10.1371/Journal.Ppat.1004082  0.268
2005 YOSHIMURA K, JAIN A, KATO Y, LAIRD L, PARDOLL D, SCHULICK R. A B16 melanoma cell line that exclusively metastasizes to the liver Journal of Gastrointestinal Surgery. 9: 582-583. DOI: 10.1016/J.Gassur.2005.01.174  0.267
2016 Nanda VGY, Peng W, Hwu P, Davies MA, Ciliberto G, Fattore L, Malpicci D, Aurisicchio L, Ascierto PA, Croce CM, Mancini R, Spranger S, Gajewski TF, Wang Y, Ferrone S, ... ... Pardoll DM, et al. Melanoma and Immunotherapy Bridge 2015 : Naples, Italy. 1-5 December 2015 Journal of Translational Medicine. 14: 65-65. PMID 27461275 DOI: 10.1186/S12967-016-0791-2  0.265
2023 Niknafs N, Balan A, Cherry C, Hummelink K, Monkhorst K, Shao XM, Belcaid Z, Marrone KA, Murray J, Smith KN, Levy B, Feliciano J, Hann CL, Lam V, Pardoll DM, et al. Persistent mutation burden drives sustained anti-tumor immune responses. Nature Medicine. PMID 36702947 DOI: 10.1038/s41591-022-02163-w  0.265
2024 Chen S, McMiller TL, Soni A, Succaria F, Sidhom JW, Cappelli LC, Casciola-Rosen LA, Morales IR, Sankaran P, Berger AE, Deutsch JS, Zhu QC, Anders RA, Hooper JE, Pardoll DM, et al. Comparing anti-tumor and anti-self immunity in a patient with melanoma receiving immune checkpoint blockade. Journal of Translational Medicine. 22: 241. PMID 38443917 DOI: 10.1186/s12967-024-04973-7  0.263
2023 Maestas DR, Chung L, Han J, Wang X, Sommerfeld SD, Kelly SH, Moore E, Nguyen HH, Mejías JC, Peña AN, Zhang H, Hooks JST, Chin AF, Andorko JI, Berlinicke CA, ... ... Pardoll DM, et al. Helminth egg derivatives as proregenerative immunotherapies. Proceedings of the National Academy of Sciences of the United States of America. 120: e2211703120. PMID 36780522 DOI: 10.1073/pnas.2211703120  0.263
1991 Yeager AM, Shinn C, Pardoll DM. Lymphoid reconstitution after transplantation of congenic hematopoietic cells in busulfan-treated mice. Blood. 78: 3312-3316. DOI: 10.1182/Blood.V78.12.3312.Bloodjournal78123312  0.263
2023 Ben-Akiva E, Karlsson J, Hemmati S, Yu H, Tzeng SY, Pardoll DM, Green JJ. Biodegradable lipophilic polymeric mRNA nanoparticles for ligand-free targeting of splenic dendritic cells for cancer vaccination. Proceedings of the National Academy of Sciences of the United States of America. 120: e2301606120. PMID 37339211 DOI: 10.1073/pnas.2301606120  0.26
2002 Greten TF, Korangy F, Neumann G, Wedemeyer H, Schlote K, Heller A, Scheffer S, Pardoll DM, Garbe AI, Schneck JP, Manns MP. Peptide-beta2-microglobulin-MHC fusion molecules bind antigen-specific T cells and can be used for multivalent MHC-Ig complexes. Journal of Immunological Methods. 271: 125-35. PMID 12445736 DOI: 10.1016/S0022-1759(02)00346-0  0.258
2015 Topalian SL, Drake CG, Pardoll DM. Immune checkpoint blockade: a common denominator approach to cancer therapy. Cancer Cell. 27: 450-61. PMID 25858804 DOI: 10.1016/j.ccell.2015.03.001  0.256
2012 Taube JM, Anders RA, Young GD, Xu H, Sharma R, McMiller TL, Chen S, Klein AP, Pardoll DM, Topalian SL, Chen L. Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape. Science Translational Medicine. 4: 127ra37. PMID 22461641 DOI: 10.1126/Scitranslmed.3003689  0.255
2017 Cho SY, Lipson EJ, Im HJ, Rowe SP, Mena E, Blackford A, Chirindel A, Pardoll DM, Topalian SL, Wahl RL. Prediction of Response to Immune Checkpoint Inhibitor Therapy Using Early Time-Point FDG-PET/CT Imaging in Patients with Advanced Melanoma. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 28360208 DOI: 10.2967/Jnumed.116.188839  0.255
2008 Trimble C, Peng S, Roden R, Gravitt P, Pardoll D, Sugar E, Thoburn C, Wu T. OR.52. Phase I Evaluation of Therapeutic, E7-targeted DNA Vaccination in Women with HPV16+ High Grade Cervical Dysplasia (CIN2/3) Clinical Immunology. 127: S22. DOI: 10.1016/J.Clim.2008.03.058  0.253
2019 Wu A, Maxwell R, Xia Y, Cardarelli P, Oyasu M, Belcaid Z, Kim E, Hung A, Luksik AS, Garzon-Muvdi T, Jackson CM, Mathios D, Theodros D, Cogswell J, Brem H, ... Pardoll DM, et al. Combination anti-CXCR4 and anti-PD-1 immunotherapy provides survival benefit in glioblastoma through immune cell modulation of tumor microenvironment. Journal of Neuro-Oncology. PMID 31025274 DOI: 10.1007/S11060-019-03172-5  0.252
2008 Rhee K, Wu S, Rabizadeh S, Wu X, Housseau F, Pardoll DM, Karim BO, Sears C. S1722 Enterotoxigenic Bacteroides Fragilis Induce E-Cadherin Shedding and TH17 Response in C57BL/6 Mice Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)61193-2  0.252
2018 Harris-Bookman S, Mathios D, Martin AM, Xia Y, Kim E, Xu H, Belcaid Z, Polanczyk M, Barberi T, Theodros D, Kim J, Taube JM, Burger PC, Selby M, Taitt C, ... ... Pardoll DM, et al. Expression of LAG-3 and efficacy of combination treatment with anti-LAG-3 and anti-PD-1 monoclonal antibodies in glioblastoma. International Journal of Cancer. PMID 30248181 DOI: 10.1002/Ijc.31661  0.252
2016 Nghiem PT, Bhatia S, Lipson EJ, Kudchadkar RR, Miller NJ, Annamalai L, Berry S, Chartash EK, Daud A, Fling SP, Friedlander PA, Kluger HM, Kohrt HE, Lundgren L, Margolin K, ... ... Pardoll DM, et al. PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma. The New England Journal of Medicine. PMID 27093365 DOI: 10.1056/NEJMoa1603702  0.251
2006 Drake CG, Jaffee E, Pardoll DM. Mechanisms of immune evasion by tumors. Advances in Immunology. 90: 51-81. PMID 16730261 DOI: 10.1016/S0065-2776(06)90002-9  0.25
2015 Boleij A, Hechenbleikner EM, Goodwin AC, Badani R, Stein EM, Lazarev MG, Ellis B, Carroll KC, Albesiano E, Wick EC, Platz EA, Pardoll DM, Sears CL. The Bacteroides fragilis toxin gene is prevalent in the colon mucosa of colorectal cancer patients. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 60: 208-15. PMID 25305284 DOI: 10.1093/Cid/Ciu787  0.25
1997 Oshiro EM, Hoffman PA, Dietsch GN, Watts MC, Pardoll DM, Tamargo RJ. Inhibition of experimental vasospasm with anti-intercellular adhesion molecule-1 monoclonal antibody in rats Stroke. 28: 2031-2038. PMID 9341715 DOI: 10.1161/01.Str.28.10.2031  0.249
2023 Han J, Cherry C, Mejias JC, Krishnan K, Ruta A, Maestas DR, Peña AN, Nguyen HH, Nagaraj S, Yang B, Gray-Gaillard E, Rutkowski N, Browne M, Tam AJ, Fertig EJ, ... ... Pardoll DM, et al. Age-associated Senescent - T Cell Signaling Promotes Type 3 Immunity that Inhibits the Biomaterial Regenerative Response. Advanced Materials (Deerfield Beach, Fla.). e2310476. PMID 38087458 DOI: 10.1002/adma.202310476  0.249
2013 Brahmer JR, Pardoll DM. Immune checkpoint inhibitors: making immunotherapy a reality for the treatment of lung cancer. Cancer Immunology Research. 1: 85-91. PMID 24777499 DOI: 10.1158/2326-6066.CIR-13-0078  0.247
2022 Shaikh FY, Gills JJ, Mohammad F, White JR, Stevens CM, Ding H, Fu J, Tam A, Blosser RL, Domingue JC, Larman TC, Chaft JE, Spicer JD, Reuss JE, Naidoo J, ... ... Pardoll DM, et al. Murine fecal microbiota transfer models selectively colonize human microbes and reveal transcriptional programs associated with response to neoadjuvant checkpoint inhibitors. Cancer Immunology, Immunotherapy : Cii. PMID 35217892 DOI: 10.1007/s00262-022-03169-6  0.245
2012 Wick EC, LeBlanc RE, Ortega G, Robinson C, Platz E, Pardoll DM, Iacobuzio-Donahue C, Sears CL. Shift from pStat6 to pStat3 predominance is associated with inflammatory bowel disease-associated dysplasia. Inflammatory Bowel Diseases. 18: 1267-74. PMID 22021169 DOI: 10.1002/Ibd.21908  0.244
2023 Brahmer JR, Drake CG, Wollner I, Powderly JD, Picus J, Sharfman WH, Stankevich E, Pons A, Salay TM, McMiller TL, Gilson MM, Wang C, Selby M, Taube JM, Anders R, ... ... Pardoll DM, et al. Phase I Study of Single-Agent Anti-Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 41: 715-723. PMID 36706735 DOI: 10.1200/JCO.22.02270  0.244
2010 Brahmer JR, Drake CG, Wollner I, Powderly JD, Picus J, Sharfman WH, Stankevich E, Pons A, Salay TM, McMiller TL, Gilson MM, Wang C, Selby M, Taube JM, Anders R, ... ... Pardoll DM, et al. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates Journal of Clinical Oncology. 28: 3167-3175. PMID 20516446 DOI: 10.1200/Jco.2009.26.7609  0.244
2021 Alteber Z, Kotturi MF, Whelan S, Ganguly S, Weyl E, Pardoll DM, Hunter J, Ophir E. Therapeutic Targeting of Checkpoint Receptors within the DNAM-1 Axis. Cancer Discovery. PMID 33687987 DOI: 10.1158/2159-8290.CD-20-1248  0.242
2013 Wrangle J, Wang W, Koch A, Easwaran H, Mohammad HP, Vendetti F, Vancriekinge W, Demeyer T, Du Z, Parsana P, Rodgers K, Yen RW, Zahnow CA, Taube JM, Brahmer JR, ... ... Pardoll D, et al. Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine. Oncotarget. 4: 2067-79. PMID 24162015 DOI: 10.18632/Oncotarget.1542  0.242
2020 Anagnostou V, Niknafs N, Marrone K, Bruhm DC, White JR, Naidoo J, Hummelink K, Monkhorst K, Lalezari F, Lanis M, Rosner S, Reuss JE, Smith KN, Adleff V, Rodgers K, ... ... Pardoll DM, et al. Multimodal genomic features predict outcome of immune checkpoint blockade in non-small-cell lung cancer. Nature Cancer. 1: 99-111. PMID 32984843 DOI: 10.1038/s43018-019-0008-8  0.239
2005 Lesniak MS, Kelleher E, Pardoll D, Cui Y. Targeted gene therapy to antigen-presenting cells in the central nervous system using hematopoietic stem cells. Neurological Research. 27: 820-6. PMID 16354542 DOI: 10.1179/016164105X49454  0.239
2012 Brahmer JR, Hodi FS, McDermott DF, Smith DC, Gettinger SN, Taube JM, Drake CG, Pardoll DM, Antonia S, Spigel DR, Atkins MB, Lawrence DP, McDonald D, Jure-Kunkel M, Korman A, et al. Anti-PD-1 (BMS-936558, MDX-1106) in patients with advanced solid tumors: Clinical activity, safety, and a potential biomarker for response. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: CRA2509. PMID 28140805 DOI: 10.1200/jco.2012.30.18_suppl.cra2509  0.235
2022 VanDyke D, Iglesias M, Tomala J, Young A, Smith J, Perry JA, Gebara E, Cross AR, Cheung LS, Dykema AG, Orcutt-Jahns BT, Henclová T, Golias J, Balolong J, Tomasovic LM, ... ... Pardoll DM, et al. Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection. Cell Reports. 41: 111478. PMID 36261022 DOI: 10.1016/j.celrep.2022.111478  0.234
2012 Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, Powderly JD, Carvajal RD, Sosman JA, Atkins MB, Leming PD, Spigel DR, Antonia SJ, Horn L, Drake CG, ... Pardoll DM, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer New England Journal of Medicine. 366: 2443-2454. PMID 22658127 DOI: 10.1056/Nejmoa1200690  0.233
2019 Sidhom JW, Theodros D, Murter B, Zarif JC, Ganguly S, Pardoll DM, Baras A. ExCYT: A Graphical User Interface for Streamlining Analysis of High-Dimensional Cytometry Data. Journal of Visualized Experiments : Jove. PMID 30735162 DOI: 10.3791/57473  0.232
2023 Shenderov E, De Marzo AM, Lotan TL, Wang H, Chan S, Lim SJ, Ji H, Allaf ME, Chapman C, Moore PA, Chen F, Sorg K, White AM, Church SE, Hudson B, ... ... Pardoll DM, et al. Neoadjuvant enoblituzumab in localized prostate cancer: a single-arm, phase 2 trial. Nature Medicine. PMID 37012549 DOI: 10.1038/s41591-023-02284-w  0.232
2020 Ben-Akiva E, Meyer RA, Yu H, Smith JT, Pardoll DM, Green JJ. Biomimetic anisotropic polymeric nanoparticles coated with red blood cell membranes for enhanced circulation and toxin removal. Science Advances. 6: eaay9035. PMID 32490199 DOI: 10.1126/Sciadv.Aay9035  0.232
2019 Zhang J, Haines C, Watson AJM, Hart AR, Platt MJ, Pardoll DM, Cosgrove SE, Gebo KA, Sears CL. Oral antibiotic use and risk of colorectal cancer in the United Kingdom, 1989-2012: a matched case-control study. Gut. PMID 31427405 DOI: 10.1136/Gutjnl-2019-318593  0.23
2021 Berry S, Giraldo NA, Green BF, Cottrell TR, Stein JE, Engle EL, Xu H, Ogurtsova A, Roberts C, Wang D, Nguyen P, Zhu Q, Soto-Diaz S, Loyola J, Sander IB, ... ... Pardoll DM, et al. Analysis of multispectral imaging with the AstroPath platform informs efficacy of PD-1 blockade. Science (New York, N.Y.). 372. PMID 34112666 DOI: 10.1126/science.aba2609  0.23
2004 Lesniak MS, Gabikian P, Tyler BM, Pardoll DM, Brem H. Dexamethasone mediated inhibition of local IL-2 immunotherapy is dose dependent in experimental brain tumors. Journal of Neuro-Oncology. 70: 23-8. PMID 15527103 DOI: 10.1023/B:Neon.0000040821.50347.C5  0.229
2019 Berry S, Giraldo N, Nguyen P, Green B, Xu H, Ogurtsova A, Soni A, Succaria F, Wang D, Roberts C, Stein J, Engle E, Pardoll D, Anders R, Cottrell T, et al. Correction to: 33rd Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2018). Journal For Immunotherapy of Cancer. 7: 46. PMID 30760319 DOI: 10.1186/S40425-019-0519-Y  0.228
2021 Shaikh FY, White JR, Gills JJ, Hakozaki T, Richard C, Routy B, Okuma Y, Usyk M, Pandey A, Weber JS, Ahn J, Lipson EJ, Naidoo J, Pardoll DM, Sears CL. A uniform computational approach improved on existing pipelines to reveal microbiome biomarkers of non-response to immune checkpoint inhibitors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33593881 DOI: 10.1158/1078-0432.CCR-20-4834  0.227
2009 Yu H, Pardoll D, Jove R. STATs in cancer inflammation and immunity: a leading role for STAT3. Nature Reviews. Cancer. 9: 798-809. PMID 19851315 DOI: 10.1038/nrc2734  0.226
2012 Brahmer JR, Tykodi SS, Chow LQ, Hwu WJ, Topalian SL, Hwu P, Drake CG, Camacho LH, Kauh J, Odunsi K, Pitot HC, Hamid O, Bhatia S, Martins R, Eaton K, ... ... Pardoll DM, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. The New England Journal of Medicine. 366: 2455-65. PMID 22658128 DOI: 10.1056/Nejmoa1200694  0.225
2008 Rabizadeh S, Wu S, Albesiano E, Wu X, Mirviss L, Rhee K, Yen H, Pardoll DM, Sears C. W1187 STAT3 Is Activated Throughout the Gastrointestinal Tract in Enterotoxigenic Bacteroides Fragilis Induced Colitis Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)63039-5  0.225
2003 Couch M, Saunders JK, O'Malley BW, Pardoll D, Jaffee E. Spatial distribution of tumor vaccine improves efficacy. The Laryngoscope. 113: 1401-5. PMID 12897566 DOI: 10.1097/00005537-200308000-00026  0.225
2019 El Asmar M, Tsai HL, Fakhry C, Maroun CA, Mandal R, Pardoll DM, Wang H. The prognostic impact of pathologic lymph nodes in HPV-positive oropharyngeal cancers. Oral Oncology. 89: 23-29. PMID 30732954 DOI: 10.1016/J.Oraloncology.2018.12.005  0.223
2021 Ligon JA, Choi W, Cojocaru G, Fu W, Hsiue EH, Oke TF, Siegel N, Fong MH, Ladle B, Pratilas CA, Morris CD, Levin A, Rhee DS, Meyer CF, Tam AJ, ... ... Pardoll DM, et al. Pathways of immune exclusion in metastatic osteosarcoma are associated with inferior patient outcomes. Journal For Immunotherapy of Cancer. 9. PMID 34021032 DOI: 10.1136/jitc-2020-001772  0.22
2008 Rabizadeh S, Albesiano E, Mirviss L, Pardoll D, Sears C. Stat3 activation in enterotoxigenic Bacteroides fragilis induced intestinal inflammation: P-098. Inflammatory Bowel Diseases. 14. DOI: 10.1097/00054725-200801001-00131  0.217
2023 Um PK, Praharaj M, Lombardo KA, Yoshida T, Matoso A, Baras AS, Zhao L, Srikrishna G, Huang J, Prasad P, Kates M, McConkey D, Pardoll DM, Bishai WR, Bivalacqua TJ. Improved bladder cancer antitumor efficacy with a recombinant BCG that releases a STING agonist. Biorxiv : the Preprint Server For Biology. PMID 38168333 DOI: 10.1101/2023.12.15.571740  0.215
2020 Markowski MC, Shenderov E, Eisenberger MA, Kachhap S, Pardoll DM, Denmeade SR, Antonarakis ES. Extreme responses to immune checkpoint blockade following bipolar androgen therapy and enzalutamide in patients with metastatic castration resistant prostate cancer. The Prostate. PMID 31972048 DOI: 10.1002/Pros.23955  0.212
2015 McDermott DF, Drake CG, Sznol M, Choueiri TK, Powderly JD, Smith DC, Brahmer JR, Carvajal RD, Hammers HJ, Puzanov I, Hodi FS, Kluger HM, Topalian SL, Pardoll DM, Wigginton JM, et al. Survival, Durable Response, and Long-Term Safety in Patients With Previously Treated Advanced Renal Cell Carcinoma Receiving Nivolumab. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 2013-20. PMID 25800770 DOI: 10.1200/JCO.2014.58.1041  0.211
2016 Mathios D, Ruzevick J, Jackson CM, Xu H, Shah SR, Taube JM, Burger PC, McCarthy EF, Quinones-Hinojosa A, Pardoll DM, Lim M. Erratum to: PD-1, PD-L1, PD-L2 expression in the chordoma microenvironment. Journal of Neuro-Oncology. PMID 27161248 DOI: 10.1007/S11060-016-2130-0  0.21
2022 Singh AK, Praharaj M, Lombardo KA, Yoshida T, Matoso A, Baras AS, Zhao L, Srikrishna G, Huang J, Prasad P, Powell JD, Kates M, McConkey D, Pardoll DM, Bishai WR, et al. Re-engineered BCG overexpressing cyclic di-AMP augments trained immunity and exhibits improved efficacy against bladder cancer. Nature Communications. 13: 878. PMID 35169141 DOI: 10.1038/s41467-022-28509-z  0.21
2005 Trimble CL, Piantadosi S, Gravitt P, Ronnett B, Pizer E, Elko A, Wilgus B, Yutzy W, Daniel R, Shah K, Peng S, Hung C, Roden R, Wu TC, Pardoll D. Spontaneous regression of high-grade cervical dysplasia: effects of human papillomavirus type and HLA phenotype. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 4717-23. PMID 16000566 DOI: 10.1158/1078-0432.Ccr-04-2599  0.208
2013 Lipson EJ, Sharfman WH, Drake CG, Wollner I, Taube JM, Anders RA, Xu H, Yao S, Pons A, Chen L, Pardoll DM, Brahmer JR, Topalian SL. Durable cancer regression off-treatment and effective reinduction therapy with an anti-PD-1 antibody. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 462-8. PMID 23169436 DOI: 10.1158/1078-0432.Ccr-12-2625  0.205
2010 Wick EC, Ortega G, Iacobuzio-Donahue CA, Pardoll DM, Sears CL. W1809 Activated STAT3 is a Marker of Neoplastic Transformation in IBD Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)63429-4  0.204
2021 Forde PM, Anagnostou V, Sun Z, Dahlberg SE, Kindler HL, Niknafs N, Purcell T, Santana-Davila R, Dudek AZ, Borghaei H, Lanis M, Belcaid Z, Smith KN, Balan A, White JR, ... ... Pardoll DM, et al. Durvalumab with platinum-pemetrexed for unresectable pleural mesothelioma: survival, genomic and immunologic analyses from the phase 2 PrE0505 trial. Nature Medicine. PMID 34750557 DOI: 10.1038/s41591-021-01541-0  0.203
2015 Gettinger SN, Horn L, Gandhi L, Spigel DR, Antonia SJ, Rizvi NA, Powderly JD, Heist RS, Carvajal RD, Jackman DM, Sequist LV, Smith DC, Leming P, Carbone DP, Pinder-Schenck MC, ... ... Pardoll DM, et al. Overall Survival and Long-Term Safety of Nivolumab (Anti-Programmed Death 1 Antibody, BMS-936558, ONO-4538) in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 2004-12. PMID 25897158 DOI: 10.1200/JCO.2014.58.3708  0.2
2006 Anand S, Wang P, Yoshimura K, Choi IH, Hilliard A, Chen YH, Wang CR, Schulick R, Flies AS, Flies DB, Zhu G, Xu Y, Pardoll DM, Chen L, Tamada K. Essential role of TNF family molecule LIGHT as a cytokine in the pathogenesis of hepatitis. The Journal of Clinical Investigation. 116: 1045-51. PMID 16557300 DOI: 10.1172/Jci27083  0.2
2011 Wu S, Onwueme K, Wu X, Ortega G, Franco-Mora A, Housseau F, Pardoll DM, Sears CL. Virulence of Enterotoxigenic Bacteroides Fragilis (ETBF) Strains is B. Fragilis Toxin (BFT) Isoform Dependent Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)62753-4  0.198
2019 Llosa NJ, Luber B, Siegel N, Awan AH, Oke T, Zhu Q, Bartlett BR, Aulakh LK, Thompson ED, Jaffee EM, Durham JN, Sears CL, Le DT, Diaz LA, Pardoll DM, et al. IMMUNOPATHOLOGIC STRATIFICATION OF COLORECTAL CANCER FOR CHECKPOINT BLOCKADE IMMUNOTHERAPY. Cancer Immunology Research. PMID 31439614 DOI: 10.1158/2326-6066.Cir-18-0927  0.197
2018 Chan JL, Wu S, Geis AL, Chan GV, Gomes TA, Beck SE, Wu X, Fan H, Tam A, Ding H, Pardoll D, Housseau F, Sears CL. 1058 - The Probiotic Potential of Non-Toxigenic Bacteroides Fragilis to Prevent Colitis and Tumorigenesis Gastroenterology. 154. DOI: 10.1016/S0016-5085(18)31073-4  0.196
2021 Sidhom JW, Larman HB, Pardoll DM, Baras AS. DeepTCR is a deep learning framework for revealing sequence concepts within T-cell repertoires. Nature Communications. 12: 1605. PMID 33707415 DOI: 10.1038/s41467-021-21879-w  0.194
2014 Taube JM, Klein A, Brahmer JR, Xu H, Pan X, Kim JH, Chen L, Pardoll DM, Topalian SL, Anders RA. Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 5064-74. PMID 24714771 DOI: 10.1158/1078-0432.Ccr-13-3271  0.194
2019 Llosa NJ, Luber B, Tam AJ, Smith KN, Siegel N, Awan AH, Fan H, Oke T, Zhang J, Domingue J, Engle EL, Roberts CA, Bartlett BR, Aulakh LK, Thompson ED, ... ... Pardoll DM, et al. INTRATUMORAL ADAPTIVE IMMUNOSUPPRESSION AND TYPE 17 IMMUNITY IN MISMATCH REPAIR PROFICIENT COLORECTAL TUMORS. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31061070 DOI: 10.1158/1078-0432.CCR-19-0114  0.193
2012 Fujita M, Zhang R, Nakata S, Kuzushima K, Wainwright DA, Balyasnikova IV, Auffinger B, Ahmed AU, Han Y, Lesniak MS, Knight A, Arnouk H, Gillespie GY, Britt W, Su Y, ... ... Pardoll DM, et al. LAB-IMMUNOLOGY RESEARCH Neuro-Oncology. 14: vi38-vi42. DOI: 10.1093/Neuonc/Nos223  0.193
2009 Wang L, Yi T, Kortylewski M, Pardoll DM, Zeng D, Yu H. IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. The Journal of Experimental Medicine. 206: 1457-64. PMID 19564351 DOI: 10.1084/jem.20090207  0.191
2018 Chung L, Orberg ET, Geis AL, Chan JL, Fu K, Shields CED, Dejea CM, Fathi P, Chen J, Finard BB, Tam AJ, McAllister FM, Fan H, Wu X, Ganguly S, ... ... Pardoll DM, et al. Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells. Cell Host & Microbe. PMID 29398651 DOI: 10.1016/j.chom.2018.01.007  0.187
2017 Payne RM, Anderson A, Parrillo A, Sadtler K, Wu I, Aston J, Steiner A, Cooney CM, Cooney DS, Byrne P, Pardoll D, Elisseeff J. Abstract 77: A Phase I Open-Label Study Evaluating the Safety of Acellular Adipose Tissue (AAT), a Novel Soft Tissue Reconstruction Solution, in Healthy Volunteers Plastic and Reconstructive Surgery. Global Open. 5: 58-59. DOI: 10.1097/01.Gox.0000516597.56514.17  0.186
2020 Sena LA, Fountain J, Isaacsson Velho P, Lim SJ, Wang H, Nizialek E, Rathi N, Nussenzveig R, Maughan BL, Velez MG, Ashkar R, Larson AC, Pritchard CC, Adra N, Bryce AH, ... ... Pardoll DM, et al. Tumor frameshift mutation proportion predicts response to immunotherapy in mismatch repair-deficient prostate cancer. The Oncologist. PMID 33215787 DOI: 10.1002/onco.13601  0.183
2018 Martin AM, Nirschl CJ, Polanczyk MJ, Bell WR, Nirschl TR, Harris-Bookman S, Phallen J, Hicks J, Martinez D, Ogurtsova A, Xu H, Sullivan LM, Meeker AK, Raabe EH, Cohen KJ, ... ... Pardoll DM, et al. PD-L1 expression in medulloblastoma: an evaluation by subgroup. Oncotarget. 9: 19177-19191. PMID 29721192 DOI: 10.18632/Oncotarget.24951  0.179
2020 Lu Z, Zou J, Li S, Topper MJ, Tao Y, Zhang H, Jiao X, Xie W, Kong X, Vaz M, Li H, Cai Y, Xia L, Huang P, Rodgers K, ... ... Pardoll DM, et al. Epigenetic therapy inhibits metastases by disrupting premetastatic niches. Nature. PMID 32103175 DOI: 10.1038/S41586-020-2054-X  0.177
2002 Sotomayor MG, Yu H, Antonia S, Sotomayor EM, Pardoll DM. Advances in gene therapy for malignant melanoma. Cancer Control : Journal of the Moffitt Cancer Center. 9: 39-48. PMID 11907465 DOI: 10.1177/107327480200900106  0.175
2023 Cherry C, Andorko JI, Krishnan K, Mejías JC, Nguyen HH, Stivers KB, Gray-Gaillard EF, Ruta A, Han J, Hamada N, Hamada M, Sturmlechner I, Trewartha S, Michel JH, Davenport Huyer L, ... ... Pardoll DM, et al. Transfer learning in a biomaterial fibrosis model identifies in vivo senescence heterogeneity and contributions to vascularization and matrix production across species and diverse pathologies. Geroscience. PMID 37079217 DOI: 10.1007/s11357-023-00785-7  0.175
2021 Sidhom JW, Larman HB, Pardoll DM, Baras AS. Author Correction: DeepTCR is a deep learning framework for revealing sequence concepts within T-cell repertoires. Nature Communications. 12: 2309. PMID 33850137 DOI: 10.1038/s41467-021-22667-2  0.175
2002 Borrello I, Pardoll D. GM-CSF-based cellular vaccines: a review of the clinical experience. Cytokine & Growth Factor Reviews. 13: 185-93. PMID 11900993 DOI: 10.1016/s1359-6101(01)00034-x  0.175
2021 Amin N, Maroun CA, El Asmar M, Alkhatib HH, Guller M, Herberg ME, Zhu G, Seiwert TY, Pardoll D, Eisele DW, Fakhry C, Gourin CG, Mandal R. Neoadjuvant immunotherapy prior to surgery for mucosal head and neck squamous cell carcinoma: Systematic review. Head & Neck. PMID 34825751 DOI: 10.1002/hed.26935  0.17
2022 Alkhatib HH, Maroun CA, Amin N, Zhu G, Guller M, Herberg ME, Wu ES, Seiwert TY, Rooper LM, Eisele DW, Fakhry C, Pardoll D, Mandal R. Tumor Histological Grade and Immunotherapy Response in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma. Jama Otolaryngology-- Head & Neck Surgery. 148: 540-546. PMID 35482301 DOI: 10.1001/jamaoto.2022.0640  0.167
2014 McAllister F, Bailey JM, Alsina J, Nirschl CJ, Sharma R, Fan H, Rattigan Y, Roeser JC, Lankapalli RH, Zhang H, Jaffee EM, Drake CG, Housseau F, Maitra A, Kolls JK, ... ... Pardoll DM, et al. Oncogenic Kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasia. Cancer Cell. 25: 621-37. PMID 24823639 DOI: 10.1016/J.Ccr.2014.03.014  0.165
2019 Lu S, Stein JE, Rimm DL, Wang DW, Bell JM, Johnson DB, Sosman JA, Schalper KA, Anders RA, Wang H, Hoyt C, Pardoll DM, Danilova L, Taube JM. Comparison of Biomarker Modalities for Predicting Response to PD-1/PD-L1 Checkpoint Blockade: A Systematic Review and Meta-analysis. Jama Oncology. PMID 31318407 DOI: 10.1001/jamaoncol.2019.1549  0.165
2020 Grasso CS, Tsoi J, Onyshchenko M, Abril-Rodriguez G, Ross-Macdonald P, Wind-Rotolo M, Champhekar A, Medina E, Torrejon DY, Shin DS, Tran P, Kim YJ, Puig-Saus C, Campbell K, Vega-Crespo A, ... ... Pardoll DM, et al. Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma. Cancer Cell. PMID 33306984 DOI: 10.1016/j.ccell.2020.11.015  0.163
2019 Naidoo J, Zhang J, Lipson EJ, Forde PM, Suresh K, Moseley KF, Mehta S, Kwatra SG, Parian AM, Kim AK, Probasco JC, Rouf R, Thorne JE, Shanbhag S, Riemer J, ... ... Pardoll DM, et al. A Multidisciplinary Toxicity Team for Cancer Immunotherapy-Related Adverse Events. Journal of the National Comprehensive Cancer Network : Jnccn. 17: 712-720. PMID 31200355 DOI: 10.6004/jnccn.2018.7268  0.162
2020 Reuss JE, Anagnostou V, Cottrell TR, Smith KN, Verde F, Zahurak M, Lanis M, Murray JC, Chan HY, McCarthy C, Wang D, White JR, Yang S, Battafarano R, Broderick S, ... ... Pardoll DM, et al. Neoadjuvant nivolumab plus ipilimumab in resectable non-small cell lung cancer. Journal For Immunotherapy of Cancer. 8. PMID 32929052 DOI: 10.1136/jitc-2020-001282  0.162
2023 Rosner S, Reuss JE, Zahurak M, Zhang J, Zeng Z, Taube J, Anagnostou V, Smith KN, Riemer J, Illei PB, Broderick SR, Jones DR, Topalian SL, Pardoll DM, Brahmer JR, et al. Five-Year Clinical Outcomes after Neoadjuvant Nivolumab in Resectable Non-Small Cell Lung Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 29: 705-710. PMID 36794455 DOI: 10.1158/1078-0432.CCR-22-2994  0.161
2023 Rosner S, Reuss JE, Zahurak M, Zhang J, Zeng Z, Taube J, Anagnostou V, Smith KN, Riemer J, Illei PB, Broderick SR, Jones DR, Topalian SL, Pardoll DM, Brahmer JR, et al. Five-Year Clinical Outcomes after Neoadjuvant Nivolumab in Resectable Non-Small Cell Lung Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. OF1-OF6. PMID 36789526 DOI: 10.1158/1078-0432.CCR-22-2994  0.161
2016 Shin DS, Zaretsky JM, Escuin-Ordinas H, Garcia-Diaz A, Hu-Lieskovan S, Kalbasi A, Grasso CS, Hugo W, Sandoval S, Torrejon DY, Palaskas N, Abril Rodriguez G, Parisi G, Azhdam A, Chmielowski B, ... ... Pardoll DM, et al. Primary Resistance to PD-1 Blockade Mediated by JAK½ Mutations. Cancer Discovery. PMID 27903500 DOI: 10.1158/2159-8290.CD-16-1223  0.158
2018 Chan JL, Wu S, Geis AL, Chan GV, Gomes TAM, Beck SE, Wu X, Fan H, Tam AJ, Chung L, Ding H, Wang H, Pardoll DM, Housseau F, Sears CL. Non-toxigenic Bacteroides fragilis (NTBF) administration reduces bacteria-driven chronic colitis and tumor development independent of polysaccharide A. Mucosal Immunology. PMID 30279518 DOI: 10.1038/s41385-018-0085-5  0.155
2015 Malm IJ, Bruno TC, Fu J, Zeng Q, Taube JM, Westra W, Pardoll D, Drake CG, Kim YJ. Expression profile and in vitro blockade of programmed death-1 in human papillomavirus-negative head and neck squamous cell carcinoma. Head & Neck. 37: 1088-95. PMID 24710745 DOI: 10.1002/hed.23706  0.154
2002 Niu G, Wright KL, Huang M, Song L, Haura E, Turkson J, Zhang S, Wang T, Sinibaldi D, Coppola D, Heller R, Ellis LM, Karras J, Bromberg J, Pardoll D, et al. Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis. Oncogene. 21: 2000-8. PMID 11960372 DOI: 10.1038/Sj.Onc.1205260  0.153
2019 Tomkovich S, Dejea CM, Winglee K, Drewes JL, Chung L, Housseau F, Pope JL, Gauthier J, Sun X, Mühlbauer M, Liu X, Fathi P, Anders RA, Besharati S, Perez-Chanona E, ... ... Pardoll DM, et al. Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic. The Journal of Clinical Investigation. 130. PMID 30855275 DOI: 10.1172/JCI124196  0.145
2010 Noonan K, Marchionni L, Anderson J, Pardoll D, Roodman GD, Borrello I. A novel role of IL-17-producing lymphocytes in mediating lytic bone disease in multiple myeloma. Blood. 116: 3554-63. PMID 20664052 DOI: 10.1182/Blood-2010-05-283895  0.145
2004 Pardoll D, Allison JP. Cancer immunotherapy: breaking the barriers to harvest the crop Nature Medicine. 10: 887-892. PMID 15340404 DOI: 10.1038/Nm0904-887  0.144
2023 Guller M, Cooper DJ, Alkhatib H, Suru A, Blancaflor A, Maroun CA, Tham T, Allen H, Mazzara E, Thomas J, Amin N, Wu E, Eisele DW, Fakhry C, Pardoll D, et al. Impact of comorbidities on outcomes in patients with advanced head and neck cancer undergoing immunotherapy. Head & Neck. PMID 37682116 DOI: 10.1002/hed.27502  0.143
2018 Dejea CM, Fathi P, Craig JM, Boleij A, Taddese R, Geis AL, Wu X, DeStefano Shields CE, Hechenbleikner EM, Huso DL, Anders RA, Giardiello FM, Wick EC, Wang H, Wu S, ... Pardoll DM, et al. Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria. Science (New York, N.Y.). 359: 592-597. PMID 29420293 DOI: 10.1126/science.aah3648  0.139
2023 Alkhatib HH, Maroun CA, Guller M, Cooper DJ, Wu ES, Eisele DW, Fakhry C, Pardoll D, Seiwert TY, Zhu G, Mandal R. Allergy History and Immunotherapy Response in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. PMID 38123496 DOI: 10.1002/ohn.582  0.133
2021 Zhu G, Amin N, Herberg ME, Maroun CA, Wang H, Guller M, Gourin CG, Rooper LM, Vosler PS, Tan M, D'Souza G, Koch WM, Eisele DW, Seiwert TY, Fakhry C, ... Pardoll DM, et al. Association of Tumor Site With the Prognosis and Immunogenomic Landscape of Human Papillomavirus-Related Head and Neck and Cervical Cancers. Jama Otolaryngology-- Head & Neck Surgery. PMID 34792560 DOI: 10.1001/jamaoto.2021.3228  0.122
2021 Shenderov E, Boudadi K, Fu W, Wang H, Sullivan R, Jordan A, Dowling D, Harb R, Schonhoft J, Jendrisak A, Carducci MA, Eisenberger MA, Eshleman JR, Luo J, Drake CG, ... Pardoll DM, et al. Nivolumab plus ipilimumab, with or without enzalutamide, in AR-V7-expressing metastatic castration-resistant prostate cancer: A phase-2 nonrandomized clinical trial. The Prostate. PMID 33636027 DOI: 10.1002/pros.24110  0.122
2024 Nichakawade TD, Ge J, Mog BJ, Lee BS, Pearlman AH, Hwang MS, DiNapoli SR, Wyhs N, Marcou N, Glavaris S, Konig MF, Gabelli SB, Watson E, Sterling C, Wagner-Johnston N, ... ... Pardoll DM, et al. TRBC1-targeting antibody-drug conjugates for the treatment of T cell cancers. Nature. PMID 38538786 DOI: 10.1038/s41586-024-07233-2  0.12
2024 Kelly RJ, Landon BV, Zaidi AH, Singh D, Canzoniero JV, Balan A, Hales RK, Voong KR, Battafarano RJ, Jobe BA, Yang SC, Broderick S, Ha J, Marrone KA, Pereira G, ... ... Pardoll DM, et al. Neoadjuvant nivolumab or nivolumab plus LAG-3 inhibitor relatlimab in resectable esophageal/gastroesophageal junction cancer: a phase Ib trial and ctDNA analyses. Nature Medicine. PMID 38504015 DOI: 10.1038/s41591-024-02877-z  0.12
2018 Forde PM, Chaft JE, Pardoll DM. Neoadjuvant PD-1 Blockade in Resectable Lung Cancer. The New England Journal of Medicine. 379: e14. PMID 30157404 DOI: 10.1056/NEJMc1808251#SA3  0.119
2009 Yoshimura K, Meckel KF, Laird LS, Chia CY, Park JJ, Olino KL, Tsunedomi R, Harada T, Iizuka N, Hazama S, Kato Y, Keller JW, Thompson JM, Chang F, Romer LH, ... ... Pardoll DM, et al. Integrin alpha2 mediates selective metastasis to the liver. Cancer Research. 69: 7320-8. PMID 19738067 DOI: 10.1158/0008-5472.Can-09-0315  0.116
2019 Shenderov E, Isaacsson Velho P, Awan AH, Wang H, Mirkheshti N, Lotan TL, Carducci MA, Pardoll DM, Eisenberger MA, Antonarakis ES. Genomic and clinical characterization of pulmonary-only metastatic prostate cancer: A unique molecular subtype. The Prostate. PMID 31389628 DOI: 10.1002/pros.23881  0.115
2023 Hahn NM, O'Donnell MA, Efstathiou JA, Zahurak M, Rosner GL, Smith J, Kates MR, Bivalacqua TJ, Tran PT, Song DY, Baras AS, Matoso A, Choi W, Smith KN, Pardoll DM, et al. A Phase 1 Trial of Durvalumab in Combination with Bacillus Calmette-Guerin (BCG) or External Beam Radiation Therapy in Patients with BCG-unresponsive Non-muscle-Invasive Bladder Cancer: The Hoosier Cancer Research Network GU16-243 ADAPT-BLADDER Study. European Urology. PMID 36717286 DOI: 10.1016/j.eururo.2023.01.017  0.108
2011 Pardoll D. Timeline: a decade of advances in immunotherapy. Nature Medicine. 17: 296. PMID 21383743 DOI: 10.1038/nm0311-296  0.106
2015 Johnson CH, Dejea CM, Edler D, Hoang LT, Santidrian AF, Felding BH, Ivanisevic J, Cho K, Wick EC, Hechenbleikner EM, Uritboonthai W, Goetz L, Casero RA, Pardoll DM, White JR, et al. Metabolism links bacterial biofilms and colon carcinogenesis. Cell Metabolism. 21: 891-7. PMID 25959674 DOI: 10.1016/J.Cmet.2015.04.011  0.101
2013 Sawyers CL, Abate-Shen C, Anderson KC, Barker A, Baselga J, Berger NA, Foti M, Jemal A, Lawrence TS, Li CI, Mardis ER, Neumann PJ, Pardoll DM, Prendergast GC, et al. AACR Cancer Progress Report 2013. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: S4-98. PMID 24045178 DOI: 10.1158/1078-0432.Ccr-13-2107  0.09
2020 Windon MJ, D'Souza G, Waterboer T, Rooper L, Westra WH, Troy T, Pardoll D, Tan M, Yavvari S, Kiess AP, Miles B, Mydlarz WK, Ha PK, Bender N, Eisele DW, et al. Risk factors for human papillomavirus-positive nonoropharyngeal squamous cell carcinoma. Head & Neck. PMID 32101350 DOI: 10.1002/hed.26116  0.088
2021 Guller M, Herberg M, Amin N, Alkhatib H, Maroun C, Wu E, Allen H, Zheng Y, Gourin C, Vosler P, Tan M, Koch W, Eisele D, Seiwert T, Fakhry C, ... Pardoll D, et al. Nutritional Status as a Predictive Biomarker for Immunotherapy Outcomes in Advanced Head and Neck Cancer. Cancers. 13. PMID 34830929 DOI: 10.3390/cancers13225772  0.082
2020 Maroun CA, Zhu G, Fakhry C, Gourin CG, Seiwert TY, Vosler PS, Tan M, Koch W, Eisele DW, Pardoll DM, Mandal R. An Immunogenomic Investigation of Oral Cavity Squamous Cell Carcinoma in Patients Aged 45 Years and Younger. The Laryngoscope. PMID 32297993 DOI: 10.1002/lary.28674  0.078
2020 Jackson CM, Choi J, Routkevitch D, Pant A, Saleh L, Ye X, Caplan JM, Huang J, McDougall CG, Pardoll DM, Brem H, Tamargo RJ, Lim M. PD-1+ Monocytes Mediate Cerebral Vasospasm Following Subarachnoid Hemorrhage. Neurosurgery. PMID 33370819 DOI: 10.1093/neuros/nyaa495  0.065
2022 Mattox AK, D'Souza G, Khan Z, Allen H, Henson S, Siewert TY, Koch W, Pardoll DM, Fakhry C. Comparison of next generation sequencing, droplet digital PCR, and quantitative real-time PCR for the earlier detection and quantification of HPV in HPV-positive oropharyngeal cancer. Oral Oncology. 128: 105805. PMID 35334415 DOI: 10.1016/j.oraloncology.2022.105805  0.054
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